Incidental Mutation 'R4967:Iqgap2'
| ID |
384143 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Iqgap2
|
| Ensembl Gene |
ENSMUSG00000021676 |
| Gene Name |
IQ motif containing GTPase activating protein 2 |
| Synonyms |
4933417J23Rik |
| MMRRC Submission |
042563-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4967 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
13 |
| Chromosomal Location |
95763685-96028788 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 95766514 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glutamic Acid
at position 1496
(D1496E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000067685
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000068603]
|
| AlphaFold |
Q3UQ44 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000068603
AA Change: D1496E
PolyPhen 2
Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)
|
| SMART Domains |
Protein: ENSMUSP00000067685
Gene: ENSMUSG00000021676
AA Change: D1496E
| Domain | Start | End | E-Value | Type |
|---|
|
CH
|
43 |
152 |
3.32e-16 |
SMART |
|
coiled coil region
|
253 |
276 |
N/A |
INTRINSIC |
|
low complexity region
|
469 |
480 |
N/A |
INTRINSIC |
|
IQ
|
689 |
711 |
1.38e-4 |
SMART |
|
IQ
|
719 |
741 |
7.36e0 |
SMART |
|
IQ
|
749 |
771 |
2.43e1 |
SMART |
|
coiled coil region
|
799 |
828 |
N/A |
INTRINSIC |
|
RasGAP
|
905 |
1258 |
2.6e-120 |
SMART |
|
Pfam:RasGAP_C
|
1367 |
1498 |
3.2e-40 |
PFAM |
|
| Meta Mutation Damage Score |
0.1315 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.5%
- 10x: 96.7%
- 20x: 93.7%
|
| Validation Efficiency |
100% (102/102) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the IQGAP family. The protein contains three IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a null mutation display reduced survival with increased incidence of hepatocellular carcinomas, increased hepatocyte apoptosis, and hepatocyte mitochondrial abnormalities. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 93 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930447C04Rik |
A |
T |
12: 72,956,502 (GRCm39) |
Y199* |
probably null |
Het |
| Adhfe1 |
A |
T |
1: 9,637,029 (GRCm39) |
I394F |
probably benign |
Het |
| Arhgap26 |
G |
T |
18: 39,379,893 (GRCm39) |
R485L |
probably damaging |
Het |
| Atat1 |
T |
A |
17: 36,212,467 (GRCm39) |
N231I |
probably damaging |
Het |
| B4galnt2 |
T |
C |
11: 95,760,100 (GRCm39) |
N309S |
probably benign |
Het |
| Bank1 |
A |
T |
3: 135,772,134 (GRCm39) |
F499I |
probably damaging |
Het |
| Bcl9l |
A |
G |
9: 44,416,365 (GRCm39) |
D146G |
possibly damaging |
Het |
| Bglap3 |
A |
T |
3: 88,283,671 (GRCm39) |
|
probably benign |
Het |
| Bscl2 |
C |
A |
19: 8,825,344 (GRCm39) |
T376K |
probably benign |
Het |
| Cercam |
A |
T |
2: 29,761,033 (GRCm39) |
|
probably null |
Het |
| Clec4f |
C |
T |
6: 83,633,012 (GRCm39) |
M1I |
probably null |
Het |
| Clec4n |
A |
T |
6: 123,209,066 (GRCm39) |
I14F |
probably benign |
Het |
| Cmya5 |
T |
C |
13: 93,227,093 (GRCm39) |
E2665G |
probably damaging |
Het |
| Cog4 |
T |
A |
8: 111,578,915 (GRCm39) |
|
probably null |
Het |
| Cubn |
A |
G |
2: 13,352,856 (GRCm39) |
F1961L |
probably benign |
Het |
| Cyp4a29 |
A |
T |
4: 115,104,196 (GRCm39) |
H88L |
probably benign |
Het |
| Dhdh |
A |
G |
7: 45,128,530 (GRCm39) |
L216P |
probably damaging |
Het |
| Dpp6 |
T |
C |
5: 27,871,509 (GRCm39) |
F544S |
probably damaging |
Het |
| Dthd1 |
C |
T |
5: 63,045,549 (GRCm39) |
T771I |
probably benign |
Het |
| Emc10 |
A |
G |
7: 44,142,612 (GRCm39) |
|
probably null |
Het |
| Fgg |
A |
T |
3: 82,920,072 (GRCm39) |
T284S |
probably benign |
Het |
| Gask1a |
C |
T |
9: 121,794,784 (GRCm39) |
R313W |
probably damaging |
Het |
| Gm3002 |
T |
A |
14: 3,824,737 (GRCm38) |
N24K |
probably damaging |
Het |
| Gm8674 |
G |
A |
13: 50,056,034 (GRCm39) |
|
noncoding transcript |
Het |
| Gpr63 |
G |
A |
4: 25,008,368 (GRCm39) |
W364* |
probably null |
Het |
| Hcn4 |
C |
G |
9: 58,767,111 (GRCm39) |
P891A |
unknown |
Het |
| Hcrtr1 |
A |
T |
4: 130,024,792 (GRCm39) |
F365I |
possibly damaging |
Het |
| Hmcn2 |
A |
G |
2: 31,244,176 (GRCm39) |
|
probably null |
Het |
| Hoxc5 |
T |
A |
15: 102,923,786 (GRCm39) |
L194H |
probably damaging |
Het |
| Ifna11 |
A |
G |
4: 88,738,287 (GRCm39) |
N31S |
probably null |
Het |
| Ikbke |
GCC |
G |
1: 131,203,004 (GRCm39) |
|
probably null |
Het |
| Kif28 |
G |
T |
1: 179,536,007 (GRCm39) |
Q556K |
probably damaging |
Het |
| Klhl42 |
C |
T |
6: 147,009,502 (GRCm39) |
T447I |
possibly damaging |
Het |
| Lrp1b |
A |
C |
2: 41,678,986 (GRCm39) |
D35E |
probably damaging |
Het |
| Lsm14b |
A |
G |
2: 179,675,692 (GRCm39) |
|
probably benign |
Het |
| Map3k1 |
T |
C |
13: 111,909,272 (GRCm39) |
E226G |
probably damaging |
Het |
| Map3k14 |
T |
A |
11: 103,130,357 (GRCm39) |
N187Y |
probably benign |
Het |
| Mcm6 |
A |
T |
1: 128,263,586 (GRCm39) |
V645E |
probably damaging |
Het |
| Mdh1b |
G |
T |
1: 63,759,022 (GRCm39) |
P190Q |
probably damaging |
Het |
| Meiob |
T |
G |
17: 25,037,353 (GRCm39) |
L77R |
probably damaging |
Het |
| Mrgpra3 |
A |
T |
7: 47,239,267 (GRCm39) |
F220I |
probably benign |
Het |
| Mrtfa |
C |
A |
15: 80,929,476 (GRCm39) |
|
probably benign |
Het |
| Mtor |
T |
A |
4: 148,575,817 (GRCm39) |
S1324T |
possibly damaging |
Het |
| Myot |
T |
A |
18: 44,487,995 (GRCm39) |
D437E |
possibly damaging |
Het |
| Ncoa6 |
G |
T |
2: 155,263,252 (GRCm39) |
T394K |
possibly damaging |
Het |
| Nf1 |
T |
A |
11: 79,456,379 (GRCm39) |
|
probably null |
Het |
| Nup210 |
T |
A |
6: 91,013,451 (GRCm39) |
T1190S |
possibly damaging |
Het |
| Odf1 |
T |
A |
15: 38,226,652 (GRCm39) |
I184N |
probably damaging |
Het |
| Or10d1 |
C |
T |
9: 39,484,054 (GRCm39) |
C167Y |
probably damaging |
Het |
| Or13d1 |
T |
C |
4: 52,970,960 (GRCm39) |
V113A |
possibly damaging |
Het |
| Or1n1b |
A |
G |
2: 36,780,719 (GRCm39) |
I47T |
probably damaging |
Het |
| Or5k15 |
G |
T |
16: 58,709,957 (GRCm39) |
Q209K |
possibly damaging |
Het |
| Padi1 |
A |
G |
4: 140,572,901 (GRCm39) |
V21A |
probably benign |
Het |
| Pdzrn3 |
C |
T |
6: 101,128,551 (GRCm39) |
R705H |
probably damaging |
Het |
| Pik3cb |
T |
C |
9: 98,987,685 (GRCm39) |
I18V |
probably benign |
Het |
| Pmpca |
T |
C |
2: 26,280,320 (GRCm39) |
S117P |
probably damaging |
Het |
| Poteg |
T |
A |
8: 27,985,009 (GRCm39) |
|
probably benign |
Het |
| Pramel32 |
T |
C |
4: 88,547,432 (GRCm39) |
T80A |
probably damaging |
Het |
| Rab30 |
G |
A |
7: 92,478,771 (GRCm39) |
R72H |
probably damaging |
Het |
| Ramp2 |
T |
A |
11: 101,138,383 (GRCm39) |
|
probably null |
Het |
| Rbks |
G |
A |
5: 31,781,876 (GRCm39) |
T308I |
probably damaging |
Het |
| Rnf112 |
A |
G |
11: 61,343,752 (GRCm39) |
|
probably benign |
Het |
| Rnf38 |
G |
A |
4: 44,152,460 (GRCm39) |
P3S |
probably damaging |
Het |
| Sec16a |
A |
G |
2: 26,302,883 (GRCm39) |
S2344P |
probably benign |
Het |
| Slc16a8 |
C |
T |
15: 79,137,084 (GRCm39) |
V109M |
possibly damaging |
Het |
| Slc28a1 |
A |
T |
7: 80,791,757 (GRCm39) |
T308S |
possibly damaging |
Het |
| Slc39a3 |
T |
C |
10: 80,867,453 (GRCm39) |
T98A |
possibly damaging |
Het |
| Smarcc2 |
T |
C |
10: 128,319,049 (GRCm39) |
F731L |
probably damaging |
Het |
| Smc4 |
A |
G |
3: 68,925,572 (GRCm39) |
|
probably benign |
Het |
| Sparcl1 |
T |
G |
5: 104,240,776 (GRCm39) |
D216A |
probably damaging |
Het |
| Speg |
G |
A |
1: 75,364,513 (GRCm39) |
R192H |
probably damaging |
Het |
| Sspo |
T |
C |
6: 48,441,539 (GRCm39) |
L1892P |
probably damaging |
Het |
| Styxl2 |
A |
T |
1: 165,954,675 (GRCm39) |
V25E |
probably damaging |
Het |
| Tacc2 |
A |
G |
7: 130,225,678 (GRCm39) |
N807D |
probably damaging |
Het |
| Teddm1a |
A |
T |
1: 153,767,979 (GRCm39) |
K148* |
probably null |
Het |
| Tex15 |
T |
A |
8: 34,064,498 (GRCm39) |
D1309E |
probably benign |
Het |
| Thbs1 |
A |
T |
2: 117,945,259 (GRCm39) |
E277D |
probably benign |
Het |
| Ticrr |
G |
A |
7: 79,310,158 (GRCm39) |
R24Q |
probably damaging |
Het |
| Tigd4 |
A |
G |
3: 84,502,460 (GRCm39) |
E459G |
probably benign |
Het |
| Tln2 |
C |
A |
9: 67,262,407 (GRCm39) |
A615S |
probably damaging |
Het |
| Tmprss5 |
T |
C |
9: 49,026,817 (GRCm39) |
V410A |
probably damaging |
Het |
| Tnrc6a |
G |
T |
7: 122,789,095 (GRCm39) |
W1638L |
probably damaging |
Het |
| Tpr |
A |
G |
1: 150,285,810 (GRCm39) |
D424G |
probably damaging |
Het |
| Trim34a |
A |
T |
7: 103,910,271 (GRCm39) |
K358* |
probably null |
Het |
| Tssk5 |
T |
A |
15: 76,258,856 (GRCm39) |
D10V |
possibly damaging |
Het |
| Usp35 |
A |
C |
7: 96,962,782 (GRCm39) |
L470R |
probably damaging |
Het |
| Usp42 |
T |
C |
5: 143,701,119 (GRCm39) |
D968G |
possibly damaging |
Het |
| Utrn |
A |
G |
10: 12,331,164 (GRCm39) |
V2924A |
probably damaging |
Het |
| Wdtc1 |
C |
A |
4: 133,021,654 (GRCm39) |
A627S |
probably damaging |
Het |
| Xrra1 |
A |
G |
7: 99,555,730 (GRCm39) |
T366A |
probably damaging |
Het |
| Zfp712 |
T |
A |
13: 67,188,773 (GRCm39) |
K585* |
probably null |
Het |
| Zfp97 |
T |
A |
17: 17,365,393 (GRCm39) |
N297K |
probably damaging |
Het |
| Zfp97 |
G |
T |
17: 17,364,938 (GRCm39) |
E146* |
probably null |
Het |
|
| Other mutations in Iqgap2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00799:Iqgap2
|
APN |
13 |
95,794,452 (GRCm39) |
splice site |
probably benign |
|
|
IGL01968:Iqgap2
|
APN |
13 |
95,772,090 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
IGL02049:Iqgap2
|
APN |
13 |
95,811,913 (GRCm39) |
splice site |
probably benign |
|
|
IGL02195:Iqgap2
|
APN |
13 |
95,798,242 (GRCm39) |
splice site |
probably benign |
|
|
IGL02387:Iqgap2
|
APN |
13 |
95,826,209 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02634:Iqgap2
|
APN |
13 |
95,764,622 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02666:Iqgap2
|
APN |
13 |
95,764,564 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02685:Iqgap2
|
APN |
13 |
95,807,912 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02927:Iqgap2
|
APN |
13 |
95,861,184 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
IGL02943:Iqgap2
|
APN |
13 |
95,798,243 (GRCm39) |
splice site |
probably benign |
|
|
IGL03167:Iqgap2
|
APN |
13 |
95,821,406 (GRCm39) |
missense |
probably benign |
0.34 |
|
IGL03169:Iqgap2
|
APN |
13 |
95,867,785 (GRCm39) |
splice site |
probably null |
|
|
IGL03293:Iqgap2
|
APN |
13 |
95,867,942 (GRCm39) |
missense |
probably damaging |
1.00 |
|
G1Funyon:Iqgap2
|
UTSW |
13 |
95,818,659 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0257:Iqgap2
|
UTSW |
13 |
95,861,052 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0335:Iqgap2
|
UTSW |
13 |
95,772,141 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0360:Iqgap2
|
UTSW |
13 |
95,867,783 (GRCm39) |
splice site |
probably benign |
|
|
R0364:Iqgap2
|
UTSW |
13 |
95,867,783 (GRCm39) |
splice site |
probably benign |
|
|
R0419:Iqgap2
|
UTSW |
13 |
95,826,207 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1229:Iqgap2
|
UTSW |
13 |
95,768,673 (GRCm39) |
missense |
probably benign |
0.32 |
|
R1290:Iqgap2
|
UTSW |
13 |
95,805,021 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1397:Iqgap2
|
UTSW |
13 |
95,768,673 (GRCm39) |
missense |
probably benign |
0.32 |
|
R1498:Iqgap2
|
UTSW |
13 |
95,783,313 (GRCm39) |
missense |
probably benign |
|
|
R1513:Iqgap2
|
UTSW |
13 |
95,766,518 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1630:Iqgap2
|
UTSW |
13 |
95,826,293 (GRCm39) |
missense |
probably benign |
|
|
R2088:Iqgap2
|
UTSW |
13 |
96,028,171 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2928:Iqgap2
|
UTSW |
13 |
95,818,744 (GRCm39) |
missense |
probably benign |
|
|
R3026:Iqgap2
|
UTSW |
13 |
95,809,564 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R3720:Iqgap2
|
UTSW |
13 |
95,805,036 (GRCm39) |
splice site |
probably null |
|
|
R3846:Iqgap2
|
UTSW |
13 |
95,810,186 (GRCm39) |
splice site |
probably benign |
|
|
R4056:Iqgap2
|
UTSW |
13 |
95,886,541 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4077:Iqgap2
|
UTSW |
13 |
95,794,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4353:Iqgap2
|
UTSW |
13 |
95,807,904 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4517:Iqgap2
|
UTSW |
13 |
95,800,569 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4628:Iqgap2
|
UTSW |
13 |
95,899,837 (GRCm39) |
missense |
probably benign |
0.17 |
|
R4686:Iqgap2
|
UTSW |
13 |
95,858,117 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4724:Iqgap2
|
UTSW |
13 |
95,772,005 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R4826:Iqgap2
|
UTSW |
13 |
95,899,783 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4847:Iqgap2
|
UTSW |
13 |
95,810,251 (GRCm39) |
missense |
probably benign |
0.19 |
|
R4973:Iqgap2
|
UTSW |
13 |
95,794,305 (GRCm39) |
splice site |
probably null |
|
|
R5010:Iqgap2
|
UTSW |
13 |
95,810,251 (GRCm39) |
missense |
probably benign |
0.19 |
|
R5086:Iqgap2
|
UTSW |
13 |
95,772,088 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5496:Iqgap2
|
UTSW |
13 |
95,766,561 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5512:Iqgap2
|
UTSW |
13 |
95,811,884 (GRCm39) |
nonsense |
probably null |
|
|
R5629:Iqgap2
|
UTSW |
13 |
95,768,682 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5824:Iqgap2
|
UTSW |
13 |
95,811,880 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5830:Iqgap2
|
UTSW |
13 |
95,811,880 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5831:Iqgap2
|
UTSW |
13 |
95,811,880 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5832:Iqgap2
|
UTSW |
13 |
95,811,880 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5833:Iqgap2
|
UTSW |
13 |
95,811,880 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5834:Iqgap2
|
UTSW |
13 |
95,811,880 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5852:Iqgap2
|
UTSW |
13 |
95,811,880 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5888:Iqgap2
|
UTSW |
13 |
95,772,118 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5889:Iqgap2
|
UTSW |
13 |
95,768,550 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6093:Iqgap2
|
UTSW |
13 |
95,765,471 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6141:Iqgap2
|
UTSW |
13 |
95,858,194 (GRCm39) |
splice site |
probably null |
|
|
R6404:Iqgap2
|
UTSW |
13 |
95,865,985 (GRCm39) |
missense |
probably benign |
0.28 |
|
R6434:Iqgap2
|
UTSW |
13 |
95,819,441 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R6648:Iqgap2
|
UTSW |
13 |
95,818,719 (GRCm39) |
missense |
probably benign |
0.27 |
|
R6658:Iqgap2
|
UTSW |
13 |
95,796,840 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6903:Iqgap2
|
UTSW |
13 |
95,797,565 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7223:Iqgap2
|
UTSW |
13 |
95,765,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7327:Iqgap2
|
UTSW |
13 |
95,772,163 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7371:Iqgap2
|
UTSW |
13 |
95,836,846 (GRCm39) |
splice site |
probably null |
|
|
R7378:Iqgap2
|
UTSW |
13 |
95,869,398 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7441:Iqgap2
|
UTSW |
13 |
95,764,584 (GRCm39) |
missense |
probably benign |
0.23 |
|
R7575:Iqgap2
|
UTSW |
13 |
95,798,131 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7671:Iqgap2
|
UTSW |
13 |
95,764,627 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7713:Iqgap2
|
UTSW |
13 |
95,867,952 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7806:Iqgap2
|
UTSW |
13 |
95,818,765 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7893:Iqgap2
|
UTSW |
13 |
95,826,217 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8052:Iqgap2
|
UTSW |
13 |
95,794,387 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8121:Iqgap2
|
UTSW |
13 |
95,861,076 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8261:Iqgap2
|
UTSW |
13 |
95,772,078 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8301:Iqgap2
|
UTSW |
13 |
95,818,659 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8369:Iqgap2
|
UTSW |
13 |
95,798,111 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8485:Iqgap2
|
UTSW |
13 |
95,796,659 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8709:Iqgap2
|
UTSW |
13 |
95,796,713 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8710:Iqgap2
|
UTSW |
13 |
95,796,756 (GRCm39) |
missense |
probably benign |
0.24 |
|
R8737:Iqgap2
|
UTSW |
13 |
95,802,258 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8845:Iqgap2
|
UTSW |
13 |
95,794,392 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R8902:Iqgap2
|
UTSW |
13 |
95,818,711 (GRCm39) |
missense |
probably benign |
0.16 |
|
R8957:Iqgap2
|
UTSW |
13 |
95,772,154 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9153:Iqgap2
|
UTSW |
13 |
95,844,547 (GRCm39) |
missense |
probably benign |
|
|
R9259:Iqgap2
|
UTSW |
13 |
95,766,561 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9290:Iqgap2
|
UTSW |
13 |
95,886,523 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9414:Iqgap2
|
UTSW |
13 |
95,783,349 (GRCm39) |
missense |
|
|
|
R9432:Iqgap2
|
UTSW |
13 |
95,774,261 (GRCm39) |
missense |
probably benign |
|
|
R9747:Iqgap2
|
UTSW |
13 |
95,821,505 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0066:Iqgap2
|
UTSW |
13 |
95,807,891 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1176:Iqgap2
|
UTSW |
13 |
95,867,951 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
| Predicted Primers |
PCR Primer
(F):5'- GGACACATAACTTCTGGGTACAC -3'
(R):5'- GCGCTGTCAGGAACATCTTG -3'
Sequencing Primer
(F):5'- CAGTGCCTGATGCTGAAGGTC -3'
(R):5'- TCAGGAACATCTTGACAACAGG -3'
|
| Posted On |
2016-04-27 |
Incidental Mutation