Incidental Mutation 'R1460:Abi3bp'
| ID |
162101 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Abi3bp
|
| Ensembl Gene |
ENSMUSG00000035258 |
| Gene Name |
ABI family member 3 binding protein |
| Synonyms |
D930038M13Rik, TARSH, 5033411B22Rik, eratin |
| MMRRC Submission |
039515-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.090)
|
| Stock # |
R1460 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
16 |
| Chromosomal Location |
56298241-56510498 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 56382780 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 130
(V130A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000156155
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000048471]
[ENSMUST00000096012]
[ENSMUST00000096013]
[ENSMUST00000171000]
[ENSMUST00000231781]
[ENSMUST00000231832]
[ENSMUST00000231870]
|
| AlphaFold |
A0A338P6S8 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000048471
AA Change: V130A
PolyPhen 2
Score 0.624 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000036257
Gene: ENSMUSG00000035258
AA Change: V130A
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
21 |
N/A |
INTRINSIC |
|
FN3
|
114 |
203 |
3.08e-2 |
SMART |
|
low complexity region
|
433 |
446 |
N/A |
INTRINSIC |
|
low complexity region
|
516 |
528 |
N/A |
INTRINSIC |
|
low complexity region
|
579 |
591 |
N/A |
INTRINSIC |
|
low complexity region
|
734 |
747 |
N/A |
INTRINSIC |
|
low complexity region
|
751 |
764 |
N/A |
INTRINSIC |
|
FN3
|
941 |
1024 |
6.29e-8 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000096012
AA Change: V130A
PolyPhen 2
Score 0.859 (Sensitivity: 0.83; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000093711
Gene: ENSMUSG00000035258
AA Change: V130A
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
21 |
N/A |
INTRINSIC |
|
FN3
|
114 |
203 |
3.08e-2 |
SMART |
|
low complexity region
|
433 |
446 |
N/A |
INTRINSIC |
|
low complexity region
|
634 |
647 |
N/A |
INTRINSIC |
|
low complexity region
|
651 |
664 |
N/A |
INTRINSIC |
|
FN3
|
841 |
924 |
6.29e-8 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000096013
AA Change: V130A
PolyPhen 2
Score 0.973 (Sensitivity: 0.76; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000093712
Gene: ENSMUSG00000035258
AA Change: V130A
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
21 |
N/A |
INTRINSIC |
|
FN3
|
114 |
203 |
3.08e-2 |
SMART |
|
low complexity region
|
433 |
446 |
N/A |
INTRINSIC |
|
low complexity region
|
670 |
683 |
N/A |
INTRINSIC |
|
low complexity region
|
687 |
700 |
N/A |
INTRINSIC |
|
FN3
|
877 |
960 |
6.29e-8 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000171000
AA Change: V130A
PolyPhen 2
Score 0.964 (Sensitivity: 0.78; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000128818
Gene: ENSMUSG00000035258
AA Change: V130A
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
21 |
N/A |
INTRINSIC |
|
FN3
|
114 |
203 |
3.08e-2 |
SMART |
|
low complexity region
|
464 |
477 |
N/A |
INTRINSIC |
|
low complexity region
|
481 |
494 |
N/A |
INTRINSIC |
|
FN3
|
671 |
754 |
6.29e-8 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000231337
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000231781
AA Change: V130A
PolyPhen 2
Score 0.992 (Sensitivity: 0.70; Specificity: 0.97)
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000231832
AA Change: V130A
PolyPhen 2
Score 0.993 (Sensitivity: 0.70; Specificity: 0.97)
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000231870
AA Change: V130A
PolyPhen 2
Score 0.810 (Sensitivity: 0.84; Specificity: 0.93)
|
| Meta Mutation Damage Score |
0.1367 |
| Coding Region Coverage |
- 1x: 98.9%
- 3x: 98.0%
- 10x: 95.2%
- 20x: 89.1%
|
| Validation Efficiency |
94% (93/99) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 96 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930522H14Rik |
A |
T |
4: 109,388,407 (GRCm39) |
|
probably null |
Het |
| Abcb11 |
A |
G |
2: 69,087,718 (GRCm39) |
|
probably benign |
Het |
| Adamts4 |
A |
G |
1: 171,084,009 (GRCm39) |
|
probably benign |
Het |
| Adgrd1 |
A |
G |
5: 129,199,627 (GRCm39) |
T155A |
possibly damaging |
Het |
| Ano3 |
A |
T |
2: 110,513,103 (GRCm39) |
S631T |
probably damaging |
Het |
| Ass1 |
G |
A |
2: 31,404,753 (GRCm39) |
V345I |
probably benign |
Het |
| Atg7 |
G |
A |
6: 114,680,325 (GRCm39) |
A384T |
probably damaging |
Het |
| Atp6v0a1 |
T |
A |
11: 100,924,824 (GRCm39) |
I303N |
probably damaging |
Het |
| B3gntl1 |
T |
G |
11: 121,530,624 (GRCm39) |
Y149S |
probably damaging |
Het |
| Btnl2 |
A |
G |
17: 34,585,424 (GRCm39) |
D475G |
probably benign |
Het |
| Cdcp1 |
A |
T |
9: 123,009,092 (GRCm39) |
S529T |
possibly damaging |
Het |
| Cenpt |
A |
G |
8: 106,575,520 (GRCm39) |
L194P |
probably damaging |
Het |
| Cfhr4 |
T |
A |
1: 139,625,934 (GRCm39) |
I788F |
probably damaging |
Het |
| Chmp4b |
A |
G |
2: 154,534,515 (GRCm39) |
D177G |
possibly damaging |
Het |
| Chmp7 |
C |
T |
14: 69,956,899 (GRCm39) |
M336I |
probably benign |
Het |
| Cish |
G |
T |
9: 107,177,596 (GRCm39) |
E91* |
probably null |
Het |
| Col22a1 |
T |
C |
15: 71,693,780 (GRCm39) |
D740G |
unknown |
Het |
| Cplane2 |
T |
C |
4: 140,945,523 (GRCm39) |
F125L |
probably damaging |
Het |
| Crocc |
G |
A |
4: 140,756,551 (GRCm39) |
Q1025* |
probably null |
Het |
| Ctrc |
C |
A |
4: 141,566,120 (GRCm39) |
|
probably benign |
Het |
| Cyb5r2 |
T |
A |
7: 107,356,450 (GRCm39) |
D7V |
probably benign |
Het |
| Dhx29 |
T |
C |
13: 113,101,744 (GRCm39) |
|
probably benign |
Het |
| Dhx9 |
A |
C |
1: 153,341,426 (GRCm39) |
D607E |
probably benign |
Het |
| Dnajb7 |
C |
T |
15: 81,291,888 (GRCm39) |
G150R |
probably benign |
Het |
| Dnase1l3 |
T |
A |
14: 7,974,050 (GRCm38) |
T214S |
probably benign |
Het |
| Dpm1 |
A |
T |
2: 168,052,549 (GRCm39) |
I229N |
probably damaging |
Het |
| Dstn |
T |
C |
2: 143,780,408 (GRCm39) |
V36A |
possibly damaging |
Het |
| Entpd1 |
T |
C |
19: 40,714,632 (GRCm39) |
V247A |
probably damaging |
Het |
| Ephb3 |
C |
A |
16: 21,037,672 (GRCm39) |
H277Q |
probably benign |
Het |
| Etl4 |
A |
T |
2: 20,793,288 (GRCm39) |
N671I |
probably damaging |
Het |
| Fabp3 |
C |
T |
4: 130,206,180 (GRCm39) |
T57I |
probably benign |
Het |
| Fancd2os |
G |
A |
6: 113,574,973 (GRCm39) |
T11I |
probably damaging |
Het |
| Fcrlb |
G |
T |
1: 170,739,853 (GRCm39) |
|
probably benign |
Het |
| Fhip1a |
T |
C |
3: 85,638,183 (GRCm39) |
I39V |
probably damaging |
Het |
| Gm9991 |
T |
C |
1: 90,606,780 (GRCm39) |
|
noncoding transcript |
Het |
| Gstk1 |
C |
T |
6: 42,223,529 (GRCm39) |
R40W |
probably damaging |
Het |
| Gstt1 |
C |
T |
10: 75,620,004 (GRCm39) |
V190M |
probably damaging |
Het |
| Hectd2 |
G |
A |
19: 36,592,908 (GRCm39) |
W691* |
probably null |
Het |
| Hecw2 |
T |
C |
1: 53,852,404 (GRCm39) |
T1572A |
probably damaging |
Het |
| Hoxa5 |
T |
C |
6: 52,180,928 (GRCm39) |
T135A |
probably benign |
Het |
| Igfl3 |
T |
A |
7: 17,913,880 (GRCm39) |
C77S |
possibly damaging |
Het |
| Itgb4 |
A |
G |
11: 115,874,990 (GRCm39) |
D449G |
probably damaging |
Het |
| Larp1b |
T |
C |
3: 40,916,653 (GRCm39) |
V11A |
probably benign |
Het |
| Lhx9 |
A |
G |
1: 138,766,447 (GRCm39) |
|
probably benign |
Het |
| Lig3 |
G |
T |
11: 82,686,624 (GRCm39) |
|
probably benign |
Het |
| Lipo4 |
A |
C |
19: 33,476,718 (GRCm39) |
F343L |
probably benign |
Het |
| Lyn |
T |
A |
4: 3,789,908 (GRCm39) |
Y480* |
probably null |
Het |
| Mib2 |
C |
T |
4: 155,743,917 (GRCm39) |
G42S |
probably damaging |
Het |
| Mill1 |
C |
A |
7: 17,996,595 (GRCm39) |
A137D |
probably damaging |
Het |
| Mmut |
T |
C |
17: 41,248,266 (GRCm39) |
Y98H |
probably damaging |
Het |
| Morc2a |
A |
T |
11: 3,633,794 (GRCm39) |
R635S |
probably benign |
Het |
| Mpped2 |
A |
G |
2: 106,575,237 (GRCm39) |
|
probably benign |
Het |
| Mug2 |
T |
C |
6: 122,017,492 (GRCm39) |
|
probably benign |
Het |
| Mynn |
C |
A |
3: 30,657,853 (GRCm39) |
S57Y |
probably damaging |
Het |
| Myo3b |
G |
A |
2: 70,062,798 (GRCm39) |
E333K |
probably benign |
Het |
| Myt1 |
A |
T |
2: 181,444,725 (GRCm39) |
I514F |
probably damaging |
Het |
| Nlrp4f |
A |
G |
13: 65,338,082 (GRCm39) |
C708R |
probably benign |
Het |
| Nod2 |
A |
G |
8: 89,390,440 (GRCm39) |
E249G |
probably damaging |
Het |
| Npy2r |
T |
C |
3: 82,448,251 (GRCm39) |
I175V |
probably benign |
Het |
| Obscn |
A |
T |
11: 58,946,792 (GRCm39) |
V4114D |
probably damaging |
Het |
| Or1l8 |
A |
T |
2: 36,817,820 (GRCm39) |
M102K |
probably damaging |
Het |
| Or2y12 |
T |
A |
11: 49,426,504 (GRCm39) |
M164K |
possibly damaging |
Het |
| Or4a76 |
A |
G |
2: 89,460,282 (GRCm39) |
|
probably null |
Het |
| Or52e7 |
T |
A |
7: 104,684,915 (GRCm39) |
I170N |
possibly damaging |
Het |
| Or8g33 |
A |
G |
9: 39,337,503 (GRCm39) |
M288T |
probably benign |
Het |
| Pbxip1 |
T |
A |
3: 89,352,921 (GRCm39) |
I196N |
probably damaging |
Het |
| Piezo1 |
G |
A |
8: 123,228,890 (GRCm39) |
T209M |
possibly damaging |
Het |
| Polr1a |
T |
C |
6: 71,918,368 (GRCm39) |
M642T |
probably damaging |
Het |
| Prdm4 |
T |
C |
10: 85,743,686 (GRCm39) |
M190V |
probably benign |
Het |
| Psmd7 |
G |
A |
8: 108,307,691 (GRCm39) |
S264L |
possibly damaging |
Het |
| Qrich1 |
T |
G |
9: 108,410,846 (GRCm39) |
|
probably benign |
Het |
| Rapgef4 |
G |
T |
2: 71,861,520 (GRCm39) |
|
probably null |
Het |
| Rfx5 |
T |
C |
3: 94,863,636 (GRCm39) |
I95T |
probably damaging |
Het |
| Rgr |
G |
A |
14: 36,767,683 (GRCm39) |
R113C |
probably damaging |
Het |
| Rnf20 |
T |
C |
4: 49,645,873 (GRCm39) |
|
probably benign |
Het |
| Rps3a1 |
G |
A |
3: 86,045,369 (GRCm39) |
A241V |
probably benign |
Het |
| Rttn |
A |
T |
18: 89,127,481 (GRCm39) |
|
probably benign |
Het |
| Scn2a |
A |
G |
2: 65,532,187 (GRCm39) |
T600A |
probably damaging |
Het |
| Scyl2 |
T |
C |
10: 89,493,751 (GRCm39) |
D339G |
possibly damaging |
Het |
| Sipa1 |
T |
A |
19: 5,701,475 (GRCm39) |
H1029L |
probably benign |
Het |
| Slc49a4 |
T |
C |
16: 35,539,736 (GRCm39) |
T362A |
probably benign |
Het |
| Snrnp48 |
A |
G |
13: 38,395,081 (GRCm39) |
T124A |
probably benign |
Het |
| Sptbn1 |
A |
T |
11: 30,088,637 (GRCm39) |
M875K |
possibly damaging |
Het |
| Supt6 |
A |
G |
11: 78,113,024 (GRCm39) |
V973A |
possibly damaging |
Het |
| Supv3l1 |
T |
C |
10: 62,279,162 (GRCm39) |
|
probably benign |
Het |
| Svep1 |
G |
T |
4: 58,068,740 (GRCm39) |
N3015K |
possibly damaging |
Het |
| Tgfb3 |
A |
G |
12: 86,105,841 (GRCm39) |
|
probably benign |
Het |
| Trerf1 |
A |
G |
17: 47,628,771 (GRCm39) |
|
noncoding transcript |
Het |
| Trim24 |
T |
A |
6: 37,941,761 (GRCm39) |
F904I |
probably damaging |
Het |
| Trim30d |
T |
A |
7: 104,121,311 (GRCm39) |
Y328F |
probably benign |
Het |
| Ttn |
T |
C |
2: 76,698,717 (GRCm39) |
E6G |
probably damaging |
Het |
| Ube2m |
T |
C |
7: 12,769,762 (GRCm39) |
|
probably benign |
Het |
| Vmn2r-ps158 |
A |
T |
7: 42,672,639 (GRCm39) |
R91S |
probably benign |
Het |
| Wdr90 |
A |
T |
17: 26,079,422 (GRCm39) |
S237R |
possibly damaging |
Het |
| Zfp735 |
A |
T |
11: 73,603,159 (GRCm39) |
H701L |
possibly damaging |
Het |
| Zp1 |
T |
C |
19: 10,896,242 (GRCm39) |
D161G |
probably benign |
Het |
|
| Other mutations in Abi3bp |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00780:Abi3bp
|
APN |
16 |
56,423,168 (GRCm39) |
missense |
probably null |
0.99 |
|
IGL01580:Abi3bp
|
APN |
16 |
56,495,573 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01633:Abi3bp
|
APN |
16 |
56,498,163 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01783:Abi3bp
|
APN |
16 |
56,353,332 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01866:Abi3bp
|
APN |
16 |
56,492,336 (GRCm39) |
missense |
probably benign |
0.19 |
|
IGL02022:Abi3bp
|
APN |
16 |
56,412,999 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02086:Abi3bp
|
APN |
16 |
56,462,930 (GRCm39) |
splice site |
probably benign |
|
|
IGL02122:Abi3bp
|
APN |
16 |
56,507,491 (GRCm39) |
splice site |
probably benign |
|
|
IGL02155:Abi3bp
|
APN |
16 |
56,408,327 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02351:Abi3bp
|
APN |
16 |
56,474,418 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL02358:Abi3bp
|
APN |
16 |
56,474,418 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL02418:Abi3bp
|
APN |
16 |
56,424,479 (GRCm39) |
splice site |
probably benign |
|
|
IGL02559:Abi3bp
|
APN |
16 |
56,507,433 (GRCm39) |
nonsense |
probably null |
|
|
IGL02617:Abi3bp
|
APN |
16 |
56,394,807 (GRCm39) |
nonsense |
probably null |
|
|
IGL02810:Abi3bp
|
APN |
16 |
56,498,138 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03057:Abi3bp
|
APN |
16 |
56,488,754 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL03174:Abi3bp
|
APN |
16 |
56,435,110 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R0389:Abi3bp
|
UTSW |
16 |
56,491,670 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R0485:Abi3bp
|
UTSW |
16 |
56,424,375 (GRCm39) |
splice site |
probably null |
|
|
R0557:Abi3bp
|
UTSW |
16 |
56,488,750 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0616:Abi3bp
|
UTSW |
16 |
56,474,433 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0685:Abi3bp
|
UTSW |
16 |
56,353,316 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0783:Abi3bp
|
UTSW |
16 |
56,415,601 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0828:Abi3bp
|
UTSW |
16 |
56,498,193 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0841:Abi3bp
|
UTSW |
16 |
56,488,639 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1078:Abi3bp
|
UTSW |
16 |
56,474,444 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1101:Abi3bp
|
UTSW |
16 |
56,426,521 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1116:Abi3bp
|
UTSW |
16 |
56,506,792 (GRCm39) |
splice site |
probably benign |
|
|
R1145:Abi3bp
|
UTSW |
16 |
56,488,639 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1145:Abi3bp
|
UTSW |
16 |
56,488,639 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1317:Abi3bp
|
UTSW |
16 |
56,488,672 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R1384:Abi3bp
|
UTSW |
16 |
56,394,862 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1730:Abi3bp
|
UTSW |
16 |
56,488,642 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R1761:Abi3bp
|
UTSW |
16 |
56,488,672 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R1830:Abi3bp
|
UTSW |
16 |
56,408,348 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1873:Abi3bp
|
UTSW |
16 |
56,394,862 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1875:Abi3bp
|
UTSW |
16 |
56,394,862 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1996:Abi3bp
|
UTSW |
16 |
56,491,720 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R2018:Abi3bp
|
UTSW |
16 |
56,498,159 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2019:Abi3bp
|
UTSW |
16 |
56,498,159 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2035:Abi3bp
|
UTSW |
16 |
56,480,581 (GRCm39) |
missense |
probably benign |
0.21 |
|
R2118:Abi3bp
|
UTSW |
16 |
56,298,227 (GRCm39) |
unclassified |
probably benign |
|
|
R2202:Abi3bp
|
UTSW |
16 |
56,471,088 (GRCm39) |
nonsense |
probably null |
|
|
R2202:Abi3bp
|
UTSW |
16 |
56,433,566 (GRCm39) |
missense |
probably benign |
0.06 |
|
R2203:Abi3bp
|
UTSW |
16 |
56,433,566 (GRCm39) |
missense |
probably benign |
0.06 |
|
R3030:Abi3bp
|
UTSW |
16 |
56,477,682 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R3952:Abi3bp
|
UTSW |
16 |
56,424,401 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R4176:Abi3bp
|
UTSW |
16 |
56,472,563 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4296:Abi3bp
|
UTSW |
16 |
56,488,673 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4301:Abi3bp
|
UTSW |
16 |
56,377,266 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4354:Abi3bp
|
UTSW |
16 |
56,353,314 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4417:Abi3bp
|
UTSW |
16 |
56,474,398 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4716:Abi3bp
|
UTSW |
16 |
56,471,088 (GRCm39) |
nonsense |
probably null |
|
|
R4808:Abi3bp
|
UTSW |
16 |
56,414,879 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4814:Abi3bp
|
UTSW |
16 |
56,471,116 (GRCm39) |
missense |
probably benign |
0.06 |
|
R5016:Abi3bp
|
UTSW |
16 |
56,491,631 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5290:Abi3bp
|
UTSW |
16 |
56,462,838 (GRCm39) |
splice site |
probably null |
|
|
R5891:Abi3bp
|
UTSW |
16 |
56,426,496 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5897:Abi3bp
|
UTSW |
16 |
56,425,032 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R6146:Abi3bp
|
UTSW |
16 |
56,491,628 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6267:Abi3bp
|
UTSW |
16 |
56,414,860 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6905:Abi3bp
|
UTSW |
16 |
56,394,880 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6908:Abi3bp
|
UTSW |
16 |
56,477,668 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6917:Abi3bp
|
UTSW |
16 |
56,437,684 (GRCm39) |
splice site |
probably null |
|
|
R7071:Abi3bp
|
UTSW |
16 |
56,449,503 (GRCm39) |
nonsense |
probably null |
|
|
R7194:Abi3bp
|
UTSW |
16 |
56,382,734 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7476:Abi3bp
|
UTSW |
16 |
56,435,109 (GRCm39) |
nonsense |
probably null |
|
|
R7554:Abi3bp
|
UTSW |
16 |
56,438,575 (GRCm39) |
splice site |
probably null |
|
|
R7571:Abi3bp
|
UTSW |
16 |
56,451,345 (GRCm39) |
splice site |
probably null |
|
|
R7661:Abi3bp
|
UTSW |
16 |
56,453,263 (GRCm39) |
splice site |
probably null |
|
|
R7662:Abi3bp
|
UTSW |
16 |
56,437,686 (GRCm39) |
splice site |
probably null |
|
|
R7910:Abi3bp
|
UTSW |
16 |
56,498,105 (GRCm39) |
nonsense |
probably null |
|
|
R8121:Abi3bp
|
UTSW |
16 |
56,452,241 (GRCm39) |
missense |
unknown |
|
|
R8781:Abi3bp
|
UTSW |
16 |
56,426,512 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8790:Abi3bp
|
UTSW |
16 |
56,495,437 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8828:Abi3bp
|
UTSW |
16 |
56,507,455 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9094:Abi3bp
|
UTSW |
16 |
56,456,590 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9135:Abi3bp
|
UTSW |
16 |
56,417,173 (GRCm39) |
missense |
probably benign |
0.21 |
|
R9282:Abi3bp
|
UTSW |
16 |
56,440,867 (GRCm39) |
missense |
unknown |
|
|
R9363:Abi3bp
|
UTSW |
16 |
56,438,575 (GRCm39) |
splice site |
probably null |
|
|
R9464:Abi3bp
|
UTSW |
16 |
56,409,046 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R9506:Abi3bp
|
UTSW |
16 |
56,437,773 (GRCm39) |
missense |
unknown |
|
|
RF008:Abi3bp
|
UTSW |
16 |
56,447,952 (GRCm39) |
intron |
probably benign |
|
|
RF016:Abi3bp
|
UTSW |
16 |
56,447,950 (GRCm39) |
frame shift |
probably null |
|
|
RF052:Abi3bp
|
UTSW |
16 |
56,447,948 (GRCm39) |
intron |
probably benign |
|
|
RF061:Abi3bp
|
UTSW |
16 |
56,447,950 (GRCm39) |
frame shift |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CATCATTTGAAAGGCACtgtactggc -3'
(R):5'- AGGGTCCAAAGTTTGTGCATTTTCCTA -3'
Sequencing Primer
(F):5'- gagcaagccaggggaag -3'
(R):5'- TATGCACATGTCACTACATCAAAAG -3'
|
| Posted On |
2014-03-14 |
Incidental Mutation