Incidental Mutation 'R1760:Znfx1'
| ID |
192671 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Znfx1
|
| Ensembl Gene |
ENSMUSG00000039501 |
| Gene Name |
zinc finger, NFX1-type containing 1 |
| Synonyms |
|
| MMRRC Submission |
039792-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1760 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
166877713-166904935 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 166881786 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Methionine to Leucine
at position 1068
(M1068L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000049404
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000018143]
[ENSMUST00000048988]
[ENSMUST00000067584]
[ENSMUST00000128676]
[ENSMUST00000155281]
|
| AlphaFold |
Q8R151 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000018143
|
| SMART Domains |
Protein: ENSMUSP00000018143
Gene: ENSMUSG00000017999
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
20 |
33 |
N/A |
INTRINSIC |
|
coiled coil region
|
78 |
106 |
N/A |
INTRINSIC |
|
low complexity region
|
133 |
148 |
N/A |
INTRINSIC |
|
low complexity region
|
157 |
166 |
N/A |
INTRINSIC |
|
DEXDc
|
203 |
404 |
2.24e-56 |
SMART |
|
HELICc
|
443 |
524 |
1.71e-29 |
SMART |
|
coiled coil region
|
577 |
613 |
N/A |
INTRINSIC |
|
low complexity region
|
622 |
629 |
N/A |
INTRINSIC |
|
low complexity region
|
644 |
657 |
N/A |
INTRINSIC |
|
low complexity region
|
679 |
692 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000048988
AA Change: M1068L
PolyPhen 2
Score 0.964 (Sensitivity: 0.78; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000049404
Gene: ENSMUSG00000039501
AA Change: M1068L
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:AAA_11
|
590 |
855 |
2.2e-17 |
PFAM |
|
Pfam:AAA_19
|
597 |
684 |
1.7e-10 |
PFAM |
|
Pfam:AAA_11
|
829 |
1033 |
1.4e-18 |
PFAM |
|
Pfam:AAA_12
|
1044 |
1228 |
3.7e-42 |
PFAM |
|
internal_repeat_2
|
1281 |
1374 |
1.33e-7 |
PROSPERO |
|
internal_repeat_1
|
1292 |
1410 |
1.32e-16 |
PROSPERO |
|
low complexity region
|
1422 |
1433 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
1434 |
1547 |
1.32e-16 |
PROSPERO |
|
internal_repeat_2
|
1453 |
1555 |
1.33e-7 |
PROSPERO |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000067584
AA Change: M204L
PolyPhen 2
Score 0.960 (Sensitivity: 0.78; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000072867
Gene: ENSMUSG00000039501
AA Change: M204L
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:AAA_11
|
8 |
170 |
1.2e-17 |
PFAM |
|
Pfam:AAA_12
|
180 |
364 |
7.4e-42 |
PFAM |
|
internal_repeat_2
|
417 |
510 |
1.08e-6 |
PROSPERO |
|
internal_repeat_1
|
428 |
546 |
1.81e-14 |
PROSPERO |
|
low complexity region
|
558 |
569 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
570 |
683 |
1.81e-14 |
PROSPERO |
|
internal_repeat_2
|
589 |
691 |
1.08e-6 |
PROSPERO |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000127468
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000128676
|
| SMART Domains |
Protein: ENSMUSP00000121598
Gene: ENSMUSG00000039501
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:AAA_11
|
590 |
837 |
1.8e-17 |
PFAM |
|
Pfam:AAA_19
|
597 |
684 |
3.4e-11 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000155281
|
| SMART Domains |
Protein: ENSMUSP00000121750
Gene: ENSMUSG00000039501
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:AAA_11
|
590 |
854 |
1.7e-17 |
PFAM |
|
Pfam:AAA_19
|
597 |
684 |
3.6e-11 |
PFAM |
|
| Meta Mutation Damage Score |
0.8162 |
| Coding Region Coverage |
- 1x: 97.5%
- 3x: 96.9%
- 10x: 95.3%
- 20x: 92.6%
|
| Validation Efficiency |
97% (95/98) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 92 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca2 |
T |
C |
2: 25,333,055 (GRCm39) |
S1585P |
probably benign |
Het |
| Abhd16b |
T |
C |
2: 181,135,197 (GRCm39) |
F33S |
probably damaging |
Het |
| Adgra2 |
G |
A |
8: 27,609,795 (GRCm39) |
R856Q |
probably damaging |
Het |
| Aff3 |
A |
T |
1: 38,368,945 (GRCm39) |
|
probably benign |
Het |
| Anxa2 |
A |
T |
9: 69,397,049 (GRCm39) |
Y251F |
probably benign |
Het |
| Arid1b |
A |
G |
17: 5,392,088 (GRCm39) |
T1873A |
probably damaging |
Het |
| Baz1b |
C |
A |
5: 135,271,378 (GRCm39) |
D1320E |
probably benign |
Het |
| Bbs1 |
A |
T |
19: 4,944,350 (GRCm39) |
S426R |
probably benign |
Het |
| Bid |
A |
G |
6: 120,877,209 (GRCm39) |
V44A |
possibly damaging |
Het |
| Ccdc60 |
T |
A |
5: 116,310,532 (GRCm39) |
M177L |
probably damaging |
Het |
| Cdh23 |
G |
A |
10: 60,161,855 (GRCm39) |
T1997M |
probably damaging |
Het |
| Cdh5 |
T |
A |
8: 104,854,801 (GRCm39) |
M243K |
probably benign |
Het |
| Clpb |
T |
A |
7: 101,435,905 (GRCm39) |
V578E |
possibly damaging |
Het |
| Cngb1 |
C |
A |
8: 96,026,328 (GRCm39) |
C151F |
probably benign |
Het |
| Cntnap5b |
T |
C |
1: 99,700,535 (GRCm39) |
S16P |
probably benign |
Het |
| Cr1l |
T |
A |
1: 194,797,123 (GRCm39) |
M305L |
probably benign |
Het |
| Ctnnal1 |
A |
T |
4: 56,838,988 (GRCm39) |
M235K |
probably damaging |
Het |
| Ddx55 |
A |
T |
5: 124,706,176 (GRCm39) |
R534W |
probably damaging |
Het |
| Dip2b |
T |
A |
15: 100,109,910 (GRCm39) |
L1465Q |
probably damaging |
Het |
| Dnah9 |
G |
T |
11: 65,872,048 (GRCm39) |
D2727E |
probably benign |
Het |
| Dph3b-ps |
A |
C |
13: 106,683,497 (GRCm39) |
|
noncoding transcript |
Het |
| Dst |
T |
A |
1: 34,267,684 (GRCm39) |
L2702Q |
probably damaging |
Het |
| Efnb2 |
T |
C |
8: 8,673,184 (GRCm39) |
T158A |
possibly damaging |
Het |
| Exosc10 |
A |
T |
4: 148,662,926 (GRCm39) |
K712* |
probably null |
Het |
| Fgr |
T |
C |
4: 132,725,653 (GRCm39) |
V354A |
possibly damaging |
Het |
| Fsip2 |
A |
G |
2: 82,830,185 (GRCm39) |
D6893G |
possibly damaging |
Het |
| Fsip2 |
G |
A |
2: 82,815,240 (GRCm39) |
V3658M |
probably benign |
Het |
| Fsip2 |
A |
T |
2: 82,818,055 (GRCm39) |
H4596L |
possibly damaging |
Het |
| Gm1527 |
G |
A |
3: 28,949,699 (GRCm39) |
|
probably benign |
Het |
| Gm5150 |
G |
T |
3: 16,060,468 (GRCm39) |
Q7K |
probably benign |
Het |
| Gpr155 |
C |
T |
2: 73,212,279 (GRCm39) |
V115M |
probably damaging |
Het |
| Gpr75 |
T |
C |
11: 30,841,527 (GRCm39) |
L144P |
probably damaging |
Het |
| Gsn |
T |
A |
2: 35,174,835 (GRCm39) |
Y127N |
probably damaging |
Het |
| Hk1 |
A |
G |
10: 62,117,678 (GRCm39) |
L615S |
probably damaging |
Het |
| Igsf9b |
A |
G |
9: 27,229,123 (GRCm39) |
T194A |
possibly damaging |
Het |
| Il17rd |
C |
T |
14: 26,813,763 (GRCm39) |
Q46* |
probably null |
Het |
| Jak1 |
T |
A |
4: 101,020,126 (GRCm39) |
M678L |
probably benign |
Het |
| Kif6 |
T |
C |
17: 49,922,311 (GRCm39) |
V16A |
probably benign |
Het |
| Kpna3 |
T |
C |
14: 61,607,990 (GRCm39) |
E405G |
probably benign |
Het |
| Lmtk2 |
C |
A |
5: 144,110,993 (GRCm39) |
T571K |
probably damaging |
Het |
| Mucl2 |
T |
C |
15: 103,927,838 (GRCm39) |
T40A |
possibly damaging |
Het |
| Myh11 |
G |
A |
16: 14,051,559 (GRCm39) |
|
probably benign |
Het |
| Myh7 |
C |
T |
14: 55,210,170 (GRCm39) |
R1845Q |
probably damaging |
Het |
| Myo1f |
T |
A |
17: 33,805,172 (GRCm39) |
L480Q |
probably benign |
Het |
| Nek9 |
T |
G |
12: 85,352,364 (GRCm39) |
D833A |
possibly damaging |
Het |
| Nek9 |
T |
C |
12: 85,357,184 (GRCm39) |
E660G |
probably benign |
Het |
| Or10z1 |
C |
T |
1: 174,077,926 (GRCm39) |
C189Y |
probably damaging |
Het |
| Or2a12 |
A |
G |
6: 42,904,431 (GRCm39) |
I89V |
possibly damaging |
Het |
| Or2t45 |
A |
G |
11: 58,669,195 (GRCm39) |
M81V |
possibly damaging |
Het |
| Or5h18 |
T |
C |
16: 58,847,350 (GRCm39) |
R307G |
probably benign |
Het |
| Or6c65 |
T |
A |
10: 129,603,417 (GRCm39) |
D17E |
probably benign |
Het |
| Or6f2 |
G |
A |
7: 139,756,188 (GRCm39) |
V52M |
probably damaging |
Het |
| Or7s1a-ps1 |
T |
A |
9: 18,843,791 (GRCm39) |
|
probably benign |
Het |
| Otud3 |
G |
T |
4: 138,623,092 (GRCm39) |
T383K |
possibly damaging |
Het |
| Pkp4 |
T |
C |
2: 59,142,185 (GRCm39) |
L496P |
probably damaging |
Het |
| Pla2g4e |
C |
A |
2: 120,000,527 (GRCm39) |
A737S |
possibly damaging |
Het |
| Pla2g4f |
T |
C |
2: 120,144,547 (GRCm39) |
|
probably benign |
Het |
| Plxnd1 |
A |
T |
6: 115,944,740 (GRCm39) |
V1018E |
possibly damaging |
Het |
| Ppp1r21 |
T |
G |
17: 88,869,653 (GRCm39) |
V402G |
possibly damaging |
Het |
| Prkcq |
T |
G |
2: 11,304,881 (GRCm39) |
M690R |
probably damaging |
Het |
| Ptpra |
T |
C |
2: 130,391,747 (GRCm39) |
I719T |
probably damaging |
Het |
| Rab3ip |
C |
T |
10: 116,773,415 (GRCm39) |
D133N |
probably damaging |
Het |
| Relch |
T |
G |
1: 105,647,169 (GRCm39) |
|
probably benign |
Het |
| Rsbn1 |
T |
A |
3: 103,867,347 (GRCm39) |
Y563N |
probably damaging |
Het |
| Rtf1 |
A |
C |
2: 119,558,889 (GRCm39) |
D530A |
probably benign |
Het |
| Rybp |
G |
T |
6: 100,209,224 (GRCm39) |
S199R |
probably benign |
Het |
| Sema5a |
T |
G |
15: 32,641,252 (GRCm39) |
C689G |
probably damaging |
Het |
| Senp6 |
T |
A |
9: 80,025,911 (GRCm39) |
V314E |
probably benign |
Het |
| Setd1a |
T |
A |
7: 127,385,062 (GRCm39) |
C47S |
possibly damaging |
Het |
| Slamf1 |
C |
A |
1: 171,604,734 (GRCm39) |
T168K |
probably benign |
Het |
| Slc12a5 |
T |
C |
2: 164,838,048 (GRCm39) |
S937P |
probably damaging |
Het |
| Slc38a11 |
C |
T |
2: 65,185,663 (GRCm39) |
|
probably null |
Het |
| Slc6a2 |
C |
T |
8: 93,687,846 (GRCm39) |
|
probably benign |
Het |
| Snw1 |
A |
T |
12: 87,511,459 (GRCm39) |
F64Y |
probably benign |
Het |
| Spata9 |
A |
C |
13: 76,146,643 (GRCm39) |
I172L |
probably benign |
Het |
| Sphkap |
T |
C |
1: 83,255,265 (GRCm39) |
H828R |
probably benign |
Het |
| Spmip6 |
T |
A |
4: 41,507,330 (GRCm39) |
|
probably null |
Het |
| Tmem94 |
A |
T |
11: 115,687,580 (GRCm39) |
K1146N |
probably damaging |
Het |
| Trdn |
A |
G |
10: 33,109,883 (GRCm39) |
T294A |
possibly damaging |
Het |
| Tsc22d1 |
T |
C |
14: 76,654,388 (GRCm39) |
V289A |
possibly damaging |
Het |
| Tti1 |
C |
A |
2: 157,834,955 (GRCm39) |
V1002L |
possibly damaging |
Het |
| Tubgcp4 |
T |
A |
2: 121,019,952 (GRCm39) |
|
probably null |
Het |
| Ush2a |
G |
A |
1: 188,643,180 (GRCm39) |
E4181K |
possibly damaging |
Het |
| Uvrag |
A |
G |
7: 98,537,555 (GRCm39) |
S547P |
probably benign |
Het |
| Vav3 |
T |
C |
3: 109,248,443 (GRCm39) |
V30A |
possibly damaging |
Het |
| Vegfa |
A |
G |
17: 46,336,395 (GRCm39) |
Y242H |
probably damaging |
Het |
| Vmn2r75 |
G |
T |
7: 85,798,019 (GRCm39) |
T598K |
probably damaging |
Het |
| Vps13b |
C |
T |
15: 35,884,765 (GRCm39) |
S3146L |
possibly damaging |
Het |
| Vrk3 |
A |
G |
7: 44,417,895 (GRCm39) |
Y310C |
probably damaging |
Het |
| Zfhx4 |
A |
G |
3: 5,447,676 (GRCm39) |
K1100R |
probably benign |
Het |
| Zfp748 |
T |
A |
13: 67,693,540 (GRCm39) |
|
probably null |
Het |
| Zfp760 |
A |
T |
17: 21,941,311 (GRCm39) |
D162V |
probably damaging |
Het |
|
| Other mutations in Znfx1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00324:Znfx1
|
APN |
2 |
166,878,649 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
IGL00492:Znfx1
|
APN |
2 |
166,878,843 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01285:Znfx1
|
APN |
2 |
166,880,615 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
IGL01343:Znfx1
|
APN |
2 |
166,879,283 (GRCm39) |
missense |
probably benign |
0.16 |
|
IGL01767:Znfx1
|
APN |
2 |
166,897,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01983:Znfx1
|
APN |
2 |
166,898,270 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02006:Znfx1
|
APN |
2 |
166,897,683 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02254:Znfx1
|
APN |
2 |
166,897,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02421:Znfx1
|
APN |
2 |
166,902,000 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02496:Znfx1
|
APN |
2 |
166,889,550 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
IGL02525:Znfx1
|
APN |
2 |
166,879,457 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02528:Znfx1
|
APN |
2 |
166,892,324 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL02537:Znfx1
|
APN |
2 |
166,898,087 (GRCm39) |
missense |
probably benign |
0.37 |
|
IGL03065:Znfx1
|
APN |
2 |
166,897,685 (GRCm39) |
missense |
probably benign |
0.00 |
|
raywing
|
UTSW |
2 |
166,879,738 (GRCm39) |
missense |
probably damaging |
1.00 |
|
sharkfin
|
UTSW |
2 |
166,898,237 (GRCm39) |
missense |
probably benign |
0.03 |
|
skate
|
UTSW |
2 |
166,880,137 (GRCm39) |
missense |
probably benign |
0.06 |
|
R0127:Znfx1
|
UTSW |
2 |
166,886,130 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R0331:Znfx1
|
UTSW |
2 |
166,888,898 (GRCm39) |
missense |
probably benign |
0.11 |
|
R0488:Znfx1
|
UTSW |
2 |
166,884,483 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R0497:Znfx1
|
UTSW |
2 |
166,897,331 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0537:Znfx1
|
UTSW |
2 |
166,883,621 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0542:Znfx1
|
UTSW |
2 |
166,897,575 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0650:Znfx1
|
UTSW |
2 |
166,889,574 (GRCm39) |
nonsense |
probably null |
|
|
R0655:Znfx1
|
UTSW |
2 |
166,898,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1104:Znfx1
|
UTSW |
2 |
166,897,560 (GRCm39) |
nonsense |
probably null |
|
|
R1470:Znfx1
|
UTSW |
2 |
166,884,507 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R1470:Znfx1
|
UTSW |
2 |
166,884,507 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R1512:Znfx1
|
UTSW |
2 |
166,898,237 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1533:Znfx1
|
UTSW |
2 |
166,898,708 (GRCm39) |
missense |
probably benign |
0.10 |
|
R1541:Znfx1
|
UTSW |
2 |
166,898,110 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1642:Znfx1
|
UTSW |
2 |
166,880,930 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1720:Znfx1
|
UTSW |
2 |
166,885,986 (GRCm39) |
nonsense |
probably null |
|
|
R1865:Znfx1
|
UTSW |
2 |
166,880,729 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1959:Znfx1
|
UTSW |
2 |
166,892,270 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2088:Znfx1
|
UTSW |
2 |
166,897,730 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4581:Znfx1
|
UTSW |
2 |
166,892,236 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4622:Znfx1
|
UTSW |
2 |
166,883,673 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R4649:Znfx1
|
UTSW |
2 |
166,898,276 (GRCm39) |
missense |
probably benign |
0.08 |
|
R4685:Znfx1
|
UTSW |
2 |
166,880,950 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4798:Znfx1
|
UTSW |
2 |
166,880,489 (GRCm39) |
splice site |
probably null |
|
|
R4827:Znfx1
|
UTSW |
2 |
166,886,151 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R4870:Znfx1
|
UTSW |
2 |
166,897,189 (GRCm39) |
missense |
probably benign |
|
|
R4910:Znfx1
|
UTSW |
2 |
166,879,402 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4910:Znfx1
|
UTSW |
2 |
166,878,724 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5022:Znfx1
|
UTSW |
2 |
166,881,746 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5023:Znfx1
|
UTSW |
2 |
166,881,746 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5057:Znfx1
|
UTSW |
2 |
166,881,746 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5061:Znfx1
|
UTSW |
2 |
166,907,318 (GRCm39) |
unclassified |
probably benign |
|
|
R5119:Znfx1
|
UTSW |
2 |
166,907,307 (GRCm39) |
unclassified |
probably benign |
|
|
R5125:Znfx1
|
UTSW |
2 |
166,888,859 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R5896:Znfx1
|
UTSW |
2 |
166,880,920 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6107:Znfx1
|
UTSW |
2 |
166,879,001 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R6112:Znfx1
|
UTSW |
2 |
166,880,126 (GRCm39) |
missense |
probably benign |
|
|
R6158:Znfx1
|
UTSW |
2 |
166,898,646 (GRCm39) |
missense |
probably benign |
0.19 |
|
R6281:Znfx1
|
UTSW |
2 |
166,897,805 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6464:Znfx1
|
UTSW |
2 |
166,888,842 (GRCm39) |
missense |
probably benign |
0.34 |
|
R6749:Znfx1
|
UTSW |
2 |
166,898,519 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6888:Znfx1
|
UTSW |
2 |
166,880,860 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R6973:Znfx1
|
UTSW |
2 |
166,898,681 (GRCm39) |
missense |
probably benign |
0.18 |
|
R7017:Znfx1
|
UTSW |
2 |
166,890,454 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7138:Znfx1
|
UTSW |
2 |
166,898,697 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7192:Znfx1
|
UTSW |
2 |
166,884,110 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7426:Znfx1
|
UTSW |
2 |
166,890,475 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7431:Znfx1
|
UTSW |
2 |
166,897,712 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7473:Znfx1
|
UTSW |
2 |
166,880,744 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7593:Znfx1
|
UTSW |
2 |
166,898,145 (GRCm39) |
missense |
probably benign |
0.28 |
|
R7732:Znfx1
|
UTSW |
2 |
166,884,589 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R7835:Znfx1
|
UTSW |
2 |
166,881,747 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7993:Znfx1
|
UTSW |
2 |
166,897,857 (GRCm39) |
nonsense |
probably null |
|
|
R8154:Znfx1
|
UTSW |
2 |
166,897,157 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8351:Znfx1
|
UTSW |
2 |
166,897,575 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8790:Znfx1
|
UTSW |
2 |
166,892,500 (GRCm39) |
intron |
probably benign |
|
|
R8953:Znfx1
|
UTSW |
2 |
166,897,421 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9005:Znfx1
|
UTSW |
2 |
166,880,656 (GRCm39) |
missense |
|
|
|
R9131:Znfx1
|
UTSW |
2 |
166,892,298 (GRCm39) |
missense |
probably benign |
|
|
R9163:Znfx1
|
UTSW |
2 |
166,898,261 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9169:Znfx1
|
UTSW |
2 |
166,897,185 (GRCm39) |
missense |
probably benign |
|
|
R9181:Znfx1
|
UTSW |
2 |
166,880,137 (GRCm39) |
missense |
probably benign |
0.06 |
|
R9181:Znfx1
|
UTSW |
2 |
166,879,738 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9300:Znfx1
|
UTSW |
2 |
166,897,860 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9448:Znfx1
|
UTSW |
2 |
166,888,844 (GRCm39) |
missense |
probably benign |
0.04 |
|
R9569:Znfx1
|
UTSW |
2 |
166,897,875 (GRCm39) |
missense |
|
|
|
X0064:Znfx1
|
UTSW |
2 |
166,897,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGCACCAGCATCTCTTGCTGAC -3'
(R):5'- CTGCTCTTCCAGATGAAGCCTCTTG -3'
Sequencing Primer
(F):5'- caagtggcaagacagattgac -3'
(R):5'- CTCCAGAAAATGGCCCTTTG -3'
|
| Posted On |
2014-05-23 |
Incidental Mutation