Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02579:Vmn2r76'

299303

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn2r76

Ensembl Gene

ENSMUSG00000091239

Gene Name

vomeronasal 2, receptor 76

Synonyms

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.166) question?

Stock #

IGL02579

Quality Score

Status

Chromosome

Chromosomal Location

85874414-85895409 bp(-) (GRCm39)

Type of Mutation

nonsense

DNA Base Change (assembly)

T to A at 85877961 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Lysine to Stop codon at position 479 (K479*)

Ref Sequence

ENSEMBL: ENSMUSP00000127309 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000165771]

AlphaFold

E9Q3F5

Predicted Effect

probably null
Transcript: ENSMUST00000165771
AA Change: K479*

SMART Domains

Protein: ENSMUSP00000127309
Gene: ENSMUSG00000091239
AA Change: K479*

Domain	Start	End	E-Value	Type
signal peptide	1	21	N/A	INTRINSIC
Pfam:ANF_receptor	78	470	1.2e-29	PFAM
low complexity region	476	489	N/A	INTRINSIC
Pfam:NCD3G	513	565	3.7e-22	PFAM
Pfam:7tm_3	598	833	1.4e-52	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 23 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcb4	A	G	5: 9,005,537 (GRCm39)	E1140G	probably damaging	Het
Alcam	T	C	16: 52,091,135 (GRCm39)	E461G	probably damaging	Het
Bahcc1	A	G	11: 120,176,175 (GRCm39)		probably benign	Het
Calhm6	C	A	10: 34,003,423 (GRCm39)	M161I	probably benign	Het
Dnmt1	A	G	9: 20,829,416 (GRCm39)	M729T	possibly damaging	Het
Enpep	G	A	3: 129,077,739 (GRCm39)	T626M	probably benign	Het
Gje1	A	T	10: 14,592,492 (GRCm39)	C97S	probably benign	Het
Igkv4-58	T	A	6: 69,477,385 (GRCm39)	I71F	probably damaging	Het
Itfg1	G	A	8: 86,507,194 (GRCm39)	T222M	possibly damaging	Het
Mon1b	G	T	8: 114,365,455 (GRCm39)	R261L	possibly damaging	Het
Mtmr6	T	A	14: 60,519,378 (GRCm39)		probably benign	Het
Nwd1	A	T	8: 73,434,155 (GRCm39)	I1251F	probably damaging	Het
Or5b101	T	C	19: 13,004,892 (GRCm39)	D267G	probably damaging	Het
Pip5k1c	C	A	10: 81,153,155 (GRCm39)		probably null	Het
Pold1	T	C	7: 44,192,703 (GRCm39)	E53G	probably damaging	Het
Prkdc	A	T	16: 15,488,465 (GRCm39)	D529V	possibly damaging	Het
Rgl2	A	G	17: 34,156,134 (GRCm39)	T741A	probably benign	Het
Tex44	A	G	1: 86,354,169 (GRCm39)	N26S	probably benign	Het
Traf5	G	T	1: 191,731,848 (GRCm39)	P28Q	probably damaging	Het
Ttn	A	G	2: 76,589,433 (GRCm39)	Y21274H	probably damaging	Het
Zfp322a	A	T	13: 23,541,613 (GRCm39)	V43E	probably damaging	Het
Zfp385c	C	A	11: 100,521,605 (GRCm39)	G152C	probably damaging	Het
Zfpm2	A	T	15: 40,962,868 (GRCm39)	N177Y	possibly damaging	Het

Other mutations in Vmn2r76

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00969:Vmn2r76	APN	7	85,877,925 (GRCm39)	missense	probably benign
IGL01374:Vmn2r76	APN	7	85,874,857 (GRCm39)	missense	probably benign	0.02
IGL01419:Vmn2r76	APN	7	85,874,910 (GRCm39)	missense	probably benign	0.32
IGL01627:Vmn2r76	APN	7	85,874,871 (GRCm39)	missense	probably damaging	1.00
IGL01730:Vmn2r76	APN	7	85,879,406 (GRCm39)	missense	probably benign	0.02
IGL01957:Vmn2r76	APN	7	85,877,925 (GRCm39)	missense	probably benign
IGL02214:Vmn2r76	APN	7	85,879,138 (GRCm39)	missense	probably benign	0.07
IGL02489:Vmn2r76	APN	7	85,878,071 (GRCm39)	missense	probably benign	0.41
IGL02543:Vmn2r76	APN	7	85,879,356 (GRCm39)	missense	probably benign	0.06
IGL02598:Vmn2r76	APN	7	85,877,879 (GRCm39)	missense	probably benign	0.05
IGL02720:Vmn2r76	APN	7	85,874,914 (GRCm39)	missense	probably benign	0.35
IGL02745:Vmn2r76	APN	7	85,879,495 (GRCm39)	missense	probably benign	0.06
IGL03393:Vmn2r76	APN	7	85,879,034 (GRCm39)	missense	probably benign	0.01
R0483:Vmn2r76	UTSW	7	85,874,959 (GRCm39)	missense	probably damaging	1.00
R0513:Vmn2r76	UTSW	7	85,877,987 (GRCm39)	missense	probably benign	0.01
R0528:Vmn2r76	UTSW	7	85,879,506 (GRCm39)	missense	possibly damaging	0.80
R0601:Vmn2r76	UTSW	7	85,875,323 (GRCm39)	critical splice acceptor site	probably null
R0662:Vmn2r76	UTSW	7	85,879,578 (GRCm39)	missense	probably benign	0.39
R0883:Vmn2r76	UTSW	7	85,877,904 (GRCm39)	missense	probably benign	0.00
R1532:Vmn2r76	UTSW	7	85,879,454 (GRCm39)	missense	probably benign	0.02
R1694:Vmn2r76	UTSW	7	85,879,356 (GRCm39)	missense	probably benign	0.06
R1696:Vmn2r76	UTSW	7	85,880,464 (GRCm39)	missense	possibly damaging	0.56
R2135:Vmn2r76	UTSW	7	85,880,219 (GRCm39)	missense	probably benign	0.02
R2151:Vmn2r76	UTSW	7	85,879,692 (GRCm39)	missense	probably benign
R2181:Vmn2r76	UTSW	7	85,874,743 (GRCm39)	missense	probably benign	0.00
R2268:Vmn2r76	UTSW	7	85,879,707 (GRCm39)	missense	probably benign	0.03
R2877:Vmn2r76	UTSW	7	85,875,201 (GRCm39)	missense	probably benign	0.00
R3155:Vmn2r76	UTSW	7	85,874,959 (GRCm39)	missense	probably damaging	1.00
R3746:Vmn2r76	UTSW	7	85,874,763 (GRCm39)	missense	probably benign	0.11
R3799:Vmn2r76	UTSW	7	85,875,244 (GRCm39)	missense	probably benign	0.00
R3825:Vmn2r76	UTSW	7	85,880,415 (GRCm39)	missense	probably benign	0.10
R4058:Vmn2r76	UTSW	7	85,879,508 (GRCm39)	missense	probably benign	0.00
R4237:Vmn2r76	UTSW	7	85,879,740 (GRCm39)	missense	probably benign	0.00
R4404:Vmn2r76	UTSW	7	85,877,511 (GRCm39)	missense	probably benign	0.16
R4796:Vmn2r76	UTSW	7	85,879,652 (GRCm39)	missense	possibly damaging	0.95
R4838:Vmn2r76	UTSW	7	85,874,733 (GRCm39)	missense	probably damaging	1.00
R5175:Vmn2r76	UTSW	7	85,877,915 (GRCm39)	missense	probably benign	0.00
R5268:Vmn2r76	UTSW	7	85,875,267 (GRCm39)	missense	probably damaging	1.00
R5381:Vmn2r76	UTSW	7	85,874,496 (GRCm39)	missense	probably damaging	1.00
R5531:Vmn2r76	UTSW	7	85,874,657 (GRCm39)	missense	probably damaging	1.00
R5566:Vmn2r76	UTSW	7	85,875,286 (GRCm39)	missense	probably damaging	1.00
R5646:Vmn2r76	UTSW	7	85,875,261 (GRCm39)	missense	probably damaging	0.98
R5664:Vmn2r76	UTSW	7	85,895,202 (GRCm39)	critical splice donor site	probably null
R5818:Vmn2r76	UTSW	7	85,879,142 (GRCm39)	missense	probably benign	0.00
R6093:Vmn2r76	UTSW	7	85,877,469 (GRCm39)	nonsense	probably null
R6651:Vmn2r76	UTSW	7	85,878,059 (GRCm39)	missense	possibly damaging	0.64
R6741:Vmn2r76	UTSW	7	85,879,560 (GRCm39)	missense	probably benign
R6750:Vmn2r76	UTSW	7	85,875,114 (GRCm39)	missense	probably damaging	1.00
R7082:Vmn2r76	UTSW	7	85,874,440 (GRCm39)	missense	probably benign	0.01
R7136:Vmn2r76	UTSW	7	85,877,975 (GRCm39)	missense	probably benign	0.06
R7524:Vmn2r76	UTSW	7	85,879,374 (GRCm39)	missense	probably benign	0.00
R7524:Vmn2r76	UTSW	7	85,874,577 (GRCm39)	missense	probably benign	0.22
R7611:Vmn2r76	UTSW	7	85,879,388 (GRCm39)	missense	probably benign	0.04
R7833:Vmn2r76	UTSW	7	85,877,892 (GRCm39)	missense	probably benign
R8002:Vmn2r76	UTSW	7	85,879,271 (GRCm39)	missense	probably benign	0.05
R8021:Vmn2r76	UTSW	7	85,874,958 (GRCm39)	missense	probably damaging	1.00
R8023:Vmn2r76	UTSW	7	85,879,028 (GRCm39)	missense	probably benign	0.00
R8250:Vmn2r76	UTSW	7	85,875,231 (GRCm39)	missense	possibly damaging	0.82
R8428:Vmn2r76	UTSW	7	85,874,479 (GRCm39)	missense	possibly damaging	0.63
R8874:Vmn2r76	UTSW	7	85,877,999 (GRCm39)	missense	probably damaging	1.00
R9139:Vmn2r76	UTSW	7	85,879,170 (GRCm39)	missense	probably benign	0.02
R9357:Vmn2r76	UTSW	7	85,880,428 (GRCm39)	missense	probably benign	0.43
Z1176:Vmn2r76	UTSW	7	85,895,271 (GRCm39)	missense	probably benign	0.39

Posted On

2015-04-16