Incidental Mutation 'IGL02614:Gm1110'
ID300600
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm1110
Ensembl Gene ENSMUSG00000079644
Gene Namepredicted gene 1110
SynonymsLOC382064
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.069) question?
Stock #IGL02614
Quality Score
Status
Chromosome9
Chromosomal Location26879567-26923111 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to G at 26920714 bp
ZygosityHeterozygous
Amino Acid Change Valine to Alanine at position 47 (V47A)
Ref Sequence ENSEMBL: ENSMUSP00000110916 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000115261]
Predicted Effect probably benign
Transcript: ENSMUST00000115261
AA Change: V47A

PolyPhen 2 Score 0.106 (Sensitivity: 0.93; Specificity: 0.86)
SMART Domains Protein: ENSMUSP00000110916
Gene: ENSMUSG00000079644
AA Change: V47A

DomainStartEndE-ValueType
signal peptide 1 24 N/A INTRINSIC
Pfam:Glyco_hydro_35 55 368 2e-93 PFAM
Pfam:Glyco_hydro_42 70 229 1e-12 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000214461
Predicted Effect noncoding transcript
Transcript: ENSMUST00000217197
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 35 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Aasdh A T 5: 76,896,368 probably benign Het
Acadsb A G 7: 131,424,628 T67A probably benign Het
Aff2 A G X: 69,864,087 D1225G possibly damaging Het
Atp2a2 T C 5: 122,489,303 D133G probably benign Het
Cacul1 A T 19: 60,563,223 M187K possibly damaging Het
Ccdc129 A T 6: 55,968,277 D661V probably damaging Het
Celf4 A G 18: 25,504,150 Y263H probably damaging Het
Cmbl G T 15: 31,589,684 V187F probably damaging Het
Epha1 T C 6: 42,360,557 N896S probably benign Het
Fbxo27 G A 7: 28,696,776 probably null Het
Galnt16 T C 12: 80,576,563 S166P probably damaging Het
Gmnn A G 13: 24,760,154 probably benign Het
Gpbp1 T C 13: 111,436,473 I382V probably benign Het
Gpr87 C A 3: 59,179,317 V256L probably damaging Het
Il4ra C A 7: 125,575,790 S390* probably null Het
Lrrc47 T C 4: 154,018,935 probably null Het
Lrriq4 A T 3: 30,655,639 L362F probably damaging Het
Lrrtm4 A T 6: 80,021,844 N79Y probably benign Het
Nr1i2 T A 16: 38,253,756 H165L probably damaging Het
Olfr1511 T C 14: 52,390,170 E201G probably damaging Het
Phf11a T A 14: 59,279,368 T214S possibly damaging Het
Prr14l A T 5: 32,830,543 I536K possibly damaging Het
Rpn1 T A 6: 88,102,105 I510N probably benign Het
Sall4 A T 2: 168,755,885 L20Q probably null Het
Sema3f T C 9: 107,682,511 E759G probably benign Het
Slc5a1 T C 5: 33,154,601 S446P probably benign Het
Srrm1 G A 4: 135,325,104 P658L unknown Het
Tcn2 C A 11: 3,926,158 S90I possibly damaging Het
Ttn T C 2: 76,711,987 T31806A possibly damaging Het
Ubr1 T C 2: 120,870,979 probably benign Het
Vac14 T G 8: 110,635,118 L214R probably damaging Het
Vmn2r58 T C 7: 41,837,129 K781E probably damaging Het
Vmn2r92 T C 17: 18,167,241 probably benign Het
Zfp518a G A 19: 40,914,617 G997R probably damaging Het
Zfp609 G A 9: 65,702,790 P964S probably damaging Het
Other mutations in Gm1110
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00591:Gm1110 APN 9 26880874 nonsense probably null
IGL01089:Gm1110 APN 9 26881860 missense probably benign
IGL01631:Gm1110 APN 9 26897916 critical splice donor site probably null
IGL02008:Gm1110 APN 9 26883230 missense probably benign 0.09
IGL02331:Gm1110 APN 9 26913287 critical splice donor site probably null
IGL02335:Gm1110 APN 9 26881763 missense probably benign 0.00
IGL02550:Gm1110 APN 9 26881834 missense probably benign 0.09
IGL03409:Gm1110 APN 9 26896620 missense probably benign 0.21
PIT4458001:Gm1110 UTSW 9 26880828 missense probably benign 0.00
R0189:Gm1110 UTSW 9 26883218 missense probably null 0.99
R0271:Gm1110 UTSW 9 26920666 missense probably damaging 1.00
R1034:Gm1110 UTSW 9 26921350 missense probably damaging 1.00
R1229:Gm1110 UTSW 9 26881806 missense probably benign
R1355:Gm1110 UTSW 9 26883761 missense probably benign 0.01
R1566:Gm1110 UTSW 9 26880870 missense probably damaging 1.00
R1574:Gm1110 UTSW 9 26881126 splice site probably benign
R1916:Gm1110 UTSW 9 26889638 missense probably damaging 1.00
R2011:Gm1110 UTSW 9 26894258 missense probably benign 0.01
R2214:Gm1110 UTSW 9 26902490 missense probably benign 0.37
R2567:Gm1110 UTSW 9 26920696 missense probably benign
R2967:Gm1110 UTSW 9 26881043 missense probably benign 0.05
R4271:Gm1110 UTSW 9 26895648 critical splice donor site probably null
R4683:Gm1110 UTSW 9 26920594 missense probably damaging 0.99
R4945:Gm1110 UTSW 9 26920595 missense possibly damaging 0.46
R5015:Gm1110 UTSW 9 26881866 missense probably benign 0.01
R5089:Gm1110 UTSW 9 26882387 missense probably damaging 0.96
R5225:Gm1110 UTSW 9 26902478 missense probably damaging 1.00
R5239:Gm1110 UTSW 9 26893570 missense probably benign 0.00
R5395:Gm1110 UTSW 9 26889632 missense probably benign
R5783:Gm1110 UTSW 9 26882336 missense probably benign
R6045:Gm1110 UTSW 9 26883209 critical splice donor site probably null
R6245:Gm1110 UTSW 9 26920747 missense probably benign 0.04
R6357:Gm1110 UTSW 9 26914128 splice site probably null
R6863:Gm1110 UTSW 9 26881064 missense probably damaging 1.00
R7336:Gm1110 UTSW 9 26914357 missense probably damaging 0.99
R7454:Gm1110 UTSW 9 26920649 missense probably benign
R7555:Gm1110 UTSW 9 26893628 missense probably benign 0.05
R7579:Gm1110 UTSW 9 26883826 missense possibly damaging 0.93
R7990:Gm1110 UTSW 9 26880841 missense possibly damaging 0.66
R8062:Gm1110 UTSW 9 26881821 missense probably damaging 0.99
R8108:Gm1110 UTSW 9 26920661 missense probably damaging 1.00
R8323:Gm1110 UTSW 9 26902423 critical splice donor site probably null
R8354:Gm1110 UTSW 9 26883280 missense probably benign 0.01
R8354:Gm1110 UTSW 9 26883281 missense probably benign 0.00
R8454:Gm1110 UTSW 9 26883280 missense probably benign 0.01
R8454:Gm1110 UTSW 9 26883281 missense probably benign 0.00
RF002:Gm1110 UTSW 9 26920640 missense probably damaging 1.00
X0063:Gm1110 UTSW 9 26894280 missense probably benign 0.01
Z1088:Gm1110 UTSW 9 26913310 missense probably benign 0.01
Posted On2015-04-16