Incidental Mutation 'R4604:Ckap5'
| ID |
345842 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ckap5
|
| Ensembl Gene |
ENSMUSG00000040549 |
| Gene Name |
cytoskeleton associated protein 5 |
| Synonyms |
D730027C18Rik, 4930432B04Rik, 3110043H24Rik |
| MMRRC Submission |
041816-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R4604 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
91357107-91451009 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 91408476 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Aspartic acid
at position 890
(E890D)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000046263
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000046769]
[ENSMUST00000099716]
[ENSMUST00000111337]
[ENSMUST00000111338]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000046769
AA Change: E890D
PolyPhen 2
Score 0.003 (Sensitivity: 0.98; Specificity: 0.44)
|
| SMART Domains |
Protein: ENSMUSP00000046263
Gene: ENSMUSG00000040549
AA Change: E890D
| Domain | Start | End | E-Value | Type |
|---|
|
TOG
|
1 |
227 |
9.27e-53 |
SMART |
|
low complexity region
|
234 |
261 |
N/A |
INTRINSIC |
|
TOG
|
269 |
506 |
1.36e-77 |
SMART |
|
low complexity region
|
537 |
551 |
N/A |
INTRINSIC |
|
TOG
|
586 |
818 |
1.29e-69 |
SMART |
|
low complexity region
|
833 |
845 |
N/A |
INTRINSIC |
|
TOG
|
850 |
1082 |
3.27e-71 |
SMART |
|
TOG
|
1191 |
1429 |
3.32e-63 |
SMART |
|
low complexity region
|
1685 |
1698 |
N/A |
INTRINSIC |
|
low complexity region
|
1759 |
1771 |
N/A |
INTRINSIC |
|
low complexity region
|
1981 |
1994 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000099716
AA Change: E890D
PolyPhen 2
Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)
|
| SMART Domains |
Protein: ENSMUSP00000097303
Gene: ENSMUSG00000040549
AA Change: E890D
| Domain | Start | End | E-Value | Type |
|---|
|
TOG
|
1 |
227 |
9.27e-53 |
SMART |
|
low complexity region
|
234 |
261 |
N/A |
INTRINSIC |
|
TOG
|
269 |
506 |
1.36e-77 |
SMART |
|
low complexity region
|
537 |
551 |
N/A |
INTRINSIC |
|
TOG
|
586 |
818 |
1.29e-69 |
SMART |
|
low complexity region
|
833 |
845 |
N/A |
INTRINSIC |
|
TOG
|
850 |
1082 |
3.27e-71 |
SMART |
|
TOG
|
1191 |
1429 |
3.32e-63 |
SMART |
|
low complexity region
|
1685 |
1698 |
N/A |
INTRINSIC |
|
low complexity region
|
1759 |
1771 |
N/A |
INTRINSIC |
|
low complexity region
|
1909 |
1921 |
N/A |
INTRINSIC |
|
low complexity region
|
2002 |
2015 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000111337
AA Change: E890D
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000106969
Gene: ENSMUSG00000040549
AA Change: E890D
| Domain | Start | End | E-Value | Type |
|---|
|
TOG
|
1 |
227 |
9.27e-53 |
SMART |
|
low complexity region
|
234 |
261 |
N/A |
INTRINSIC |
|
TOG
|
269 |
506 |
1.36e-77 |
SMART |
|
low complexity region
|
537 |
551 |
N/A |
INTRINSIC |
|
TOG
|
586 |
818 |
1.29e-69 |
SMART |
|
low complexity region
|
833 |
845 |
N/A |
INTRINSIC |
|
TOG
|
850 |
1082 |
3.27e-71 |
SMART |
|
TOG
|
1191 |
1429 |
3.32e-63 |
SMART |
|
low complexity region
|
1625 |
1638 |
N/A |
INTRINSIC |
|
low complexity region
|
1699 |
1711 |
N/A |
INTRINSIC |
|
low complexity region
|
1849 |
1861 |
N/A |
INTRINSIC |
|
low complexity region
|
1942 |
1955 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000111338
AA Change: E890D
PolyPhen 2
Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)
|
| SMART Domains |
Protein: ENSMUSP00000106970
Gene: ENSMUSG00000040549
AA Change: E890D
| Domain | Start | End | E-Value | Type |
|---|
|
TOG
|
1 |
227 |
9.27e-53 |
SMART |
|
low complexity region
|
234 |
261 |
N/A |
INTRINSIC |
|
TOG
|
269 |
506 |
1.36e-77 |
SMART |
|
low complexity region
|
537 |
551 |
N/A |
INTRINSIC |
|
TOG
|
586 |
818 |
1.29e-69 |
SMART |
|
low complexity region
|
833 |
845 |
N/A |
INTRINSIC |
|
TOG
|
850 |
1082 |
3.27e-71 |
SMART |
|
TOG
|
1191 |
1429 |
3.32e-63 |
SMART |
|
low complexity region
|
1685 |
1698 |
N/A |
INTRINSIC |
|
low complexity region
|
1759 |
1771 |
N/A |
INTRINSIC |
|
low complexity region
|
1909 |
1921 |
N/A |
INTRINSIC |
|
low complexity region
|
2002 |
2015 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.2%
- 20x: 95.1%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a cytoskeleton-associated protein which belongs to the TOG/XMAP215 family. The N-terminal half of this protein contains a microtubule-binding domain and the C-terminal half contains a KXGS motif for binding tubulin dimers. This protein has two distinct roles in spindle formation; it protects kinetochore microtubules from depolymerization and plays an essential role in centrosomal microtubule assembly. This protein may be necessary for the proper interaction of microtubules with the cell cortex for directional cell movement. It also plays a role in translation of the myelin basic protein (MBP) mRNA by interacting with heterogeneous nuclear ribonucleoprotein (hnRNP) A2, which associates with MBP. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
PHENOTYPE: Mice homozygous for a transgenic gene disruption exhibit decreased body size and cleft palate. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 106 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930518I15Rik |
C |
T |
2: 156,699,074 (GRCm39) |
|
probably benign |
Het |
| Abcb6 |
G |
A |
1: 75,156,521 (GRCm39) |
T81I |
probably benign |
Het |
| Acp6 |
A |
G |
3: 97,083,075 (GRCm39) |
K362R |
probably benign |
Het |
| Adam26a |
A |
G |
8: 44,023,088 (GRCm39) |
M134T |
probably benign |
Het |
| Ankrd27 |
C |
T |
7: 35,327,915 (GRCm39) |
P812S |
probably damaging |
Het |
| Arl6ip1 |
AAAATAAATAAATAAATAAATAAATA |
AAAATAAATAAATAAATAAATAAATAAATA |
7: 117,721,122 (GRCm39) |
|
probably benign |
Het |
| Atp2a1 |
G |
A |
7: 126,047,795 (GRCm39) |
R672C |
probably damaging |
Het |
| Atxn2 |
G |
T |
5: 121,919,406 (GRCm39) |
W371C |
probably damaging |
Het |
| B3gnt2 |
T |
TTCACAAA |
11: 22,786,426 (GRCm39) |
|
probably null |
Het |
| Btnl6 |
T |
A |
17: 34,727,435 (GRCm39) |
D365V |
possibly damaging |
Het |
| Ccdc80 |
T |
A |
16: 44,915,928 (GRCm39) |
L228Q |
probably damaging |
Het |
| Cdc42bpa |
A |
G |
1: 179,936,759 (GRCm39) |
H718R |
probably benign |
Het |
| Cdh18 |
A |
G |
15: 23,474,454 (GRCm39) |
K775E |
probably benign |
Het |
| Cdh23 |
T |
G |
10: 60,173,445 (GRCm39) |
N1679T |
possibly damaging |
Het |
| Cep192 |
T |
A |
18: 67,948,993 (GRCm39) |
D271E |
possibly damaging |
Het |
| Cfap70 |
G |
T |
14: 20,493,729 (GRCm39) |
T124K |
probably benign |
Het |
| Col22a1 |
G |
T |
15: 71,824,188 (GRCm39) |
P569T |
probably benign |
Het |
| Colq |
A |
T |
14: 31,267,060 (GRCm39) |
L150Q |
possibly damaging |
Het |
| Csf1 |
T |
C |
3: 107,664,278 (GRCm39) |
|
probably null |
Het |
| Csmd3 |
A |
T |
15: 47,868,211 (GRCm39) |
S770T |
possibly damaging |
Het |
| Cul9 |
C |
A |
17: 46,841,072 (GRCm39) |
V733L |
probably damaging |
Het |
| Cyp2c55 |
A |
G |
19: 39,019,830 (GRCm39) |
D256G |
possibly damaging |
Het |
| Dclk3 |
A |
T |
9: 111,298,253 (GRCm39) |
D599V |
probably damaging |
Het |
| Defb26 |
T |
A |
2: 152,350,104 (GRCm39) |
I59F |
possibly damaging |
Het |
| Dnah6 |
A |
G |
6: 73,106,643 (GRCm39) |
V1646A |
possibly damaging |
Het |
| Dnm2 |
T |
C |
9: 21,415,960 (GRCm39) |
|
probably null |
Het |
| Dock6 |
A |
G |
9: 21,713,836 (GRCm39) |
L1867P |
probably damaging |
Het |
| Dock9 |
G |
T |
14: 121,905,871 (GRCm39) |
T93K |
probably damaging |
Het |
| Dync2h1 |
T |
C |
9: 7,140,995 (GRCm39) |
H1344R |
probably benign |
Het |
| Enam |
A |
C |
5: 88,652,142 (GRCm39) |
Q1217P |
possibly damaging |
Het |
| Fbf1 |
A |
T |
11: 116,049,748 (GRCm39) |
D91E |
possibly damaging |
Het |
| Fbxo7 |
T |
G |
10: 85,882,666 (GRCm39) |
W393G |
probably damaging |
Het |
| Gab2 |
A |
G |
7: 96,953,420 (GRCm39) |
T599A |
probably damaging |
Het |
| Gfy |
T |
A |
7: 44,826,612 (GRCm39) |
I409F |
possibly damaging |
Het |
| Gm19345 |
T |
A |
7: 19,591,433 (GRCm39) |
|
probably null |
Het |
| Gm4787 |
A |
G |
12: 81,425,987 (GRCm39) |
M57T |
probably benign |
Het |
| Gper1 |
A |
G |
5: 139,412,480 (GRCm39) |
E275G |
probably damaging |
Het |
| Grik4 |
T |
C |
9: 42,435,882 (GRCm39) |
E803G |
probably damaging |
Het |
| Gstm3 |
G |
A |
3: 107,875,513 (GRCm39) |
P39L |
possibly damaging |
Het |
| Hax1 |
A |
T |
3: 89,904,767 (GRCm39) |
V142D |
probably damaging |
Het |
| Hcn3 |
A |
T |
3: 89,057,747 (GRCm39) |
I383N |
probably damaging |
Het |
| Hdac10 |
C |
A |
15: 89,009,600 (GRCm39) |
|
probably null |
Het |
| Hipk3 |
A |
C |
2: 104,269,674 (GRCm39) |
M505R |
probably damaging |
Het |
| Hivep1 |
C |
T |
13: 42,313,225 (GRCm39) |
P1822S |
probably benign |
Het |
| Hsd17b13 |
G |
T |
5: 104,104,124 (GRCm39) |
H281N |
unknown |
Het |
| Ilrun |
T |
C |
17: 28,039,289 (GRCm39) |
D7G |
probably damaging |
Het |
| Irak2 |
T |
A |
6: 113,649,848 (GRCm39) |
I222N |
probably damaging |
Het |
| Kalrn |
G |
A |
16: 34,334,296 (GRCm39) |
L7F |
possibly damaging |
Het |
| Kcnma1 |
A |
G |
14: 23,359,106 (GRCm39) |
|
probably null |
Het |
| Kcnn3 |
G |
T |
3: 89,427,727 (GRCm39) |
|
probably benign |
Het |
| Lamb1 |
A |
C |
12: 31,328,775 (GRCm39) |
D218A |
probably damaging |
Het |
| Lrrtm1 |
A |
T |
6: 77,221,127 (GRCm39) |
N195Y |
probably damaging |
Het |
| Ltf |
A |
T |
9: 110,851,409 (GRCm39) |
N72I |
probably damaging |
Het |
| Mcm4 |
A |
G |
16: 15,447,527 (GRCm39) |
I479T |
probably damaging |
Het |
| Mfhas1 |
T |
C |
8: 36,055,764 (GRCm39) |
S80P |
probably benign |
Het |
| Mknk1 |
A |
G |
4: 115,735,224 (GRCm39) |
E364G |
probably damaging |
Het |
| Msh4 |
C |
T |
3: 153,577,920 (GRCm39) |
C458Y |
probably damaging |
Het |
| Mtrr |
A |
T |
13: 68,712,631 (GRCm39) |
|
probably null |
Het |
| Myo1a |
T |
C |
10: 127,547,007 (GRCm39) |
W356R |
probably damaging |
Het |
| Nbea |
A |
G |
3: 55,631,069 (GRCm39) |
V2186A |
probably benign |
Het |
| Nfe2l3 |
T |
C |
6: 51,427,992 (GRCm39) |
S185P |
probably damaging |
Het |
| Nhsl1 |
A |
C |
10: 18,407,158 (GRCm39) |
K1397Q |
probably damaging |
Het |
| Nmbr |
C |
T |
10: 14,645,908 (GRCm39) |
R261W |
probably damaging |
Het |
| Npy2r |
A |
G |
3: 82,448,365 (GRCm39) |
S137P |
probably damaging |
Het |
| Obscn |
C |
T |
11: 58,971,031 (GRCm39) |
G2494D |
probably damaging |
Het |
| Obscn |
T |
C |
11: 59,013,572 (GRCm39) |
K1092E |
probably damaging |
Het |
| Oosp2 |
A |
C |
19: 11,627,047 (GRCm39) |
I92S |
probably benign |
Het |
| Or5ar1 |
C |
T |
2: 85,671,526 (GRCm39) |
C203Y |
probably damaging |
Het |
| Pcdh9 |
T |
C |
14: 94,124,616 (GRCm39) |
D518G |
probably damaging |
Het |
| Pde11a |
G |
T |
2: 76,168,137 (GRCm39) |
T272K |
possibly damaging |
Het |
| Plekha2 |
T |
A |
8: 25,549,851 (GRCm39) |
Q162L |
probably null |
Het |
| Prkag2 |
T |
A |
5: 25,083,732 (GRCm39) |
I84F |
probably damaging |
Het |
| Prm2 |
G |
T |
16: 10,609,613 (GRCm39) |
|
probably benign |
Het |
| Prpf40a |
A |
T |
2: 53,032,035 (GRCm39) |
C800S |
probably damaging |
Het |
| Prr5l |
A |
T |
2: 101,559,793 (GRCm39) |
C158S |
probably benign |
Het |
| Prrt3 |
C |
A |
6: 113,475,198 (GRCm39) |
C8F |
possibly damaging |
Het |
| Psg25 |
T |
C |
7: 18,263,728 (GRCm39) |
T32A |
probably benign |
Het |
| Ruvbl1 |
T |
C |
6: 88,462,887 (GRCm39) |
V337A |
probably benign |
Het |
| Sall1 |
T |
A |
8: 89,756,969 (GRCm39) |
Q1045L |
probably damaging |
Het |
| Sec22c |
T |
C |
9: 121,524,708 (GRCm39) |
Y25C |
probably damaging |
Het |
| Serpina3i |
A |
T |
12: 104,234,036 (GRCm39) |
T335S |
possibly damaging |
Het |
| Setd1b |
TCCACCACCACCACCACCACCACCA |
TCCACCACCACCACCACCACCA |
5: 123,290,137 (GRCm39) |
|
probably benign |
Het |
| Slc12a8 |
T |
A |
16: 33,428,529 (GRCm39) |
I279N |
probably damaging |
Het |
| Slc15a1 |
G |
A |
14: 121,727,319 (GRCm39) |
T83I |
probably damaging |
Het |
| Slc22a3 |
A |
G |
17: 12,678,658 (GRCm39) |
F222S |
probably benign |
Het |
| Sorcs3 |
A |
T |
19: 48,682,353 (GRCm39) |
T463S |
probably benign |
Het |
| Spsb4 |
C |
A |
9: 96,877,931 (GRCm39) |
A131S |
probably benign |
Het |
| Sting1 |
T |
A |
18: 35,871,743 (GRCm39) |
I170F |
probably damaging |
Het |
| Syne2 |
A |
G |
12: 76,014,484 (GRCm39) |
E3225G |
probably damaging |
Het |
| Tchp |
G |
A |
5: 114,857,634 (GRCm39) |
|
probably null |
Het |
| Tekt4 |
T |
A |
17: 25,690,749 (GRCm39) |
D18E |
probably benign |
Het |
| Timm50 |
A |
G |
7: 28,010,443 (GRCm39) |
V37A |
probably benign |
Het |
| Tlx2 |
A |
C |
6: 83,045,741 (GRCm39) |
*285G |
probably null |
Het |
| Tshz1 |
C |
A |
18: 84,031,499 (GRCm39) |
D970Y |
probably damaging |
Het |
| Ttn |
A |
T |
2: 76,700,805 (GRCm39) |
V50E |
probably damaging |
Het |
| Txndc17 |
T |
A |
11: 72,100,274 (GRCm39) |
S113T |
probably benign |
Het |
| Tyk2 |
T |
C |
9: 21,019,305 (GRCm39) |
Y1039C |
probably damaging |
Het |
| Ubqln3 |
A |
G |
7: 103,791,698 (GRCm39) |
S131P |
probably benign |
Het |
| Uncx |
A |
T |
5: 139,529,837 (GRCm39) |
H30L |
possibly damaging |
Het |
| Usp25 |
T |
A |
16: 76,912,303 (GRCm39) |
D1007E |
probably damaging |
Het |
| Usp47 |
T |
C |
7: 111,701,038 (GRCm39) |
V1083A |
probably damaging |
Het |
| Wdr24 |
T |
A |
17: 26,047,479 (GRCm39) |
H765Q |
probably damaging |
Het |
| Wrnip1 |
A |
G |
13: 32,986,330 (GRCm39) |
D37G |
probably damaging |
Het |
| Xpo6 |
T |
C |
7: 125,712,924 (GRCm39) |
T686A |
possibly damaging |
Het |
| Zfp941 |
G |
A |
7: 140,392,124 (GRCm39) |
R412C |
probably damaging |
Het |
| Znrf2 |
T |
A |
6: 54,855,425 (GRCm39) |
C71* |
probably null |
Het |
|
| Other mutations in Ckap5 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00508:Ckap5
|
APN |
2 |
91,436,601 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00566:Ckap5
|
APN |
2 |
91,398,972 (GRCm39) |
splice site |
probably benign |
|
|
IGL00585:Ckap5
|
APN |
2 |
91,450,170 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00910:Ckap5
|
APN |
2 |
91,406,395 (GRCm39) |
missense |
probably benign |
0.32 |
|
IGL01309:Ckap5
|
APN |
2 |
91,400,529 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01411:Ckap5
|
APN |
2 |
91,431,356 (GRCm39) |
missense |
probably benign |
0.26 |
|
IGL01654:Ckap5
|
APN |
2 |
91,407,954 (GRCm39) |
missense |
probably benign |
0.26 |
|
IGL01684:Ckap5
|
APN |
2 |
91,385,699 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL02031:Ckap5
|
APN |
2 |
91,443,117 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
IGL02057:Ckap5
|
APN |
2 |
91,431,052 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL02101:Ckap5
|
APN |
2 |
91,402,885 (GRCm39) |
splice site |
probably benign |
|
|
IGL02250:Ckap5
|
APN |
2 |
91,379,246 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02556:Ckap5
|
APN |
2 |
91,425,186 (GRCm39) |
splice site |
probably benign |
|
|
IGL02620:Ckap5
|
APN |
2 |
91,436,714 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02627:Ckap5
|
APN |
2 |
91,406,366 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02693:Ckap5
|
APN |
2 |
91,400,556 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02808:Ckap5
|
APN |
2 |
91,426,859 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03086:Ckap5
|
APN |
2 |
91,400,621 (GRCm39) |
splice site |
probably benign |
|
|
Elephantine
|
UTSW |
2 |
91,406,614 (GRCm39) |
missense |
probably damaging |
1.00 |
|
hardiness
|
UTSW |
2 |
91,445,445 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
total
|
UTSW |
2 |
91,400,597 (GRCm39) |
missense |
probably damaging |
0.99 |
|
K7371:Ckap5
|
UTSW |
2 |
91,425,868 (GRCm39) |
splice site |
probably benign |
|
|
R0106:Ckap5
|
UTSW |
2 |
91,446,185 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0106:Ckap5
|
UTSW |
2 |
91,408,550 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0114:Ckap5
|
UTSW |
2 |
91,450,457 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0464:Ckap5
|
UTSW |
2 |
91,409,858 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0633:Ckap5
|
UTSW |
2 |
91,381,088 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0723:Ckap5
|
UTSW |
2 |
91,385,676 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1037:Ckap5
|
UTSW |
2 |
91,380,974 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1139:Ckap5
|
UTSW |
2 |
91,411,488 (GRCm39) |
missense |
probably benign |
0.11 |
|
R1161:Ckap5
|
UTSW |
2 |
91,429,720 (GRCm39) |
missense |
probably null |
1.00 |
|
R1183:Ckap5
|
UTSW |
2 |
91,416,611 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1660:Ckap5
|
UTSW |
2 |
91,393,303 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1850:Ckap5
|
UTSW |
2 |
91,426,058 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1951:Ckap5
|
UTSW |
2 |
91,386,837 (GRCm39) |
splice site |
probably benign |
|
|
R1968:Ckap5
|
UTSW |
2 |
91,416,688 (GRCm39) |
missense |
probably benign |
0.10 |
|
R2004:Ckap5
|
UTSW |
2 |
91,437,891 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R2143:Ckap5
|
UTSW |
2 |
91,396,090 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2391:Ckap5
|
UTSW |
2 |
91,416,214 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R2435:Ckap5
|
UTSW |
2 |
91,411,490 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2438:Ckap5
|
UTSW |
2 |
91,425,753 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R2680:Ckap5
|
UTSW |
2 |
91,419,043 (GRCm39) |
missense |
probably benign |
|
|
R2698:Ckap5
|
UTSW |
2 |
91,408,426 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3420:Ckap5
|
UTSW |
2 |
91,400,597 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3422:Ckap5
|
UTSW |
2 |
91,400,597 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3696:Ckap5
|
UTSW |
2 |
91,450,511 (GRCm39) |
missense |
probably benign |
0.15 |
|
R3698:Ckap5
|
UTSW |
2 |
91,450,511 (GRCm39) |
missense |
probably benign |
0.15 |
|
R3877:Ckap5
|
UTSW |
2 |
91,445,495 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R4453:Ckap5
|
UTSW |
2 |
91,379,190 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4605:Ckap5
|
UTSW |
2 |
91,406,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4849:Ckap5
|
UTSW |
2 |
91,445,616 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5267:Ckap5
|
UTSW |
2 |
91,422,097 (GRCm39) |
missense |
probably null |
1.00 |
|
R5367:Ckap5
|
UTSW |
2 |
91,445,486 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R5481:Ckap5
|
UTSW |
2 |
91,402,792 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R5546:Ckap5
|
UTSW |
2 |
91,425,161 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5704:Ckap5
|
UTSW |
2 |
91,406,548 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5786:Ckap5
|
UTSW |
2 |
91,446,641 (GRCm39) |
splice site |
probably null |
|
|
R5793:Ckap5
|
UTSW |
2 |
91,450,180 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R5824:Ckap5
|
UTSW |
2 |
91,389,481 (GRCm39) |
missense |
probably benign |
0.34 |
|
R5841:Ckap5
|
UTSW |
2 |
91,431,027 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5875:Ckap5
|
UTSW |
2 |
91,391,206 (GRCm39) |
missense |
probably benign |
|
|
R5935:Ckap5
|
UTSW |
2 |
91,445,445 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R6008:Ckap5
|
UTSW |
2 |
91,393,334 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6174:Ckap5
|
UTSW |
2 |
91,398,564 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6343:Ckap5
|
UTSW |
2 |
91,426,819 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6624:Ckap5
|
UTSW |
2 |
91,407,996 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6786:Ckap5
|
UTSW |
2 |
91,387,920 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6793:Ckap5
|
UTSW |
2 |
91,399,054 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6841:Ckap5
|
UTSW |
2 |
91,400,597 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6972:Ckap5
|
UTSW |
2 |
91,436,658 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7044:Ckap5
|
UTSW |
2 |
91,407,946 (GRCm39) |
missense |
probably benign |
|
|
R7111:Ckap5
|
UTSW |
2 |
91,437,917 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7790:Ckap5
|
UTSW |
2 |
91,389,455 (GRCm39) |
missense |
probably benign |
|
|
R7809:Ckap5
|
UTSW |
2 |
91,436,702 (GRCm39) |
missense |
probably benign |
0.28 |
|
R7921:Ckap5
|
UTSW |
2 |
91,379,285 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8125:Ckap5
|
UTSW |
2 |
91,406,614 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8331:Ckap5
|
UTSW |
2 |
91,406,545 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8342:Ckap5
|
UTSW |
2 |
91,436,707 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R8511:Ckap5
|
UTSW |
2 |
91,445,492 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8708:Ckap5
|
UTSW |
2 |
91,425,823 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8946:Ckap5
|
UTSW |
2 |
91,409,861 (GRCm39) |
missense |
probably benign |
0.44 |
|
R8982:Ckap5
|
UTSW |
2 |
91,437,923 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R9113:Ckap5
|
UTSW |
2 |
91,426,144 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9161:Ckap5
|
UTSW |
2 |
91,445,653 (GRCm39) |
missense |
probably benign |
|
|
R9238:Ckap5
|
UTSW |
2 |
91,399,027 (GRCm39) |
missense |
probably null |
0.10 |
|
R9339:Ckap5
|
UTSW |
2 |
91,396,100 (GRCm39) |
missense |
probably benign |
|
|
R9571:Ckap5
|
UTSW |
2 |
91,387,953 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9718:Ckap5
|
UTSW |
2 |
91,379,177 (GRCm39) |
missense |
probably benign |
0.10 |
|
X0010:Ckap5
|
UTSW |
2 |
91,426,854 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
Z1177:Ckap5
|
UTSW |
2 |
91,416,143 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGATCAGGTAGGTTTTATCCTGAGA -3'
(R):5'- CCCTCAAAGCCCTGACATTT -3'
Sequencing Primer
(F):5'- ATAGTATAGGCTGGCCTTGAACCC -3'
(R):5'- CCTCAAAGCCCTGACATTTATAAATC -3'
|
| Posted On |
2015-09-25 |
Incidental Mutation