Incidental Mutation 'IGL03032:Cyp2b9'
ID408504
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Cyp2b9
Ensembl Gene ENSMUSG00000040660
Gene Namecytochrome P450, family 2, subfamily b, polypeptide 9
Synonyms16\alphaoh-a, phenobarbitol inducible, type a, Cyp2b
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.108) question?
Stock #IGL03032
Quality Score
Status
Chromosome7
Chromosomal Location26173411-26210661 bp(+) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) T to C at 26198600 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000080846 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000082214]
Predicted Effect probably benign
Transcript: ENSMUST00000082214
SMART Domains Protein: ENSMUSP00000080846
Gene: ENSMUSG00000040660

DomainStartEndE-ValueType
signal peptide 1 24 N/A INTRINSIC
Pfam:p450 31 488 1.7e-146 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 37 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
2310003L06Rik A T 5: 87,971,915 Y177F possibly damaging Het
Als2 C A 1: 59,216,030 probably benign Het
Arhgap44 A G 11: 65,024,212 L410P probably damaging Het
Atp13a2 C T 4: 141,000,355 A481V possibly damaging Het
Bod1l C A 5: 41,831,584 L393F probably benign Het
Cflar T A 1: 58,741,020 I258N probably damaging Het
Col24a1 T C 3: 145,538,703 probably null Het
Csmd2 A T 4: 128,519,041 N2542I probably benign Het
Dip2c A T 13: 9,551,778 I258F probably damaging Het
Dock7 A G 4: 98,966,348 S1560P probably benign Het
Drc7 C T 8: 95,076,247 probably benign Het
Gm3667 T A 14: 6,872,191 S203C probably null Het
Gramd2 A G 9: 59,712,127 E190G probably benign Het
Gstm4 T C 3: 108,043,947 D8G probably damaging Het
Heatr5b A T 17: 78,760,499 M1820K probably benign Het
Irs4 A G X: 141,722,798 Y801H unknown Het
Loxhd1 C T 18: 77,286,473 T80I possibly damaging Het
Lrrc40 G A 3: 158,041,665 probably benign Het
Mapk8ip1 T G 2: 92,386,613 K446Q probably damaging Het
Mettl21e C A 1: 44,210,159 probably null Het
Mmp8 T A 9: 7,558,529 probably benign Het
Muc19 A T 15: 91,910,539 noncoding transcript Het
Nipsnap3b T A 4: 53,015,016 V21E possibly damaging Het
Olfr1040 A G 2: 86,146,699 F12L probably damaging Het
Olfr1354 A T 10: 78,917,637 I266F probably benign Het
Olfr344 C A 2: 36,568,704 Y35* probably null Het
Parp12 G A 6: 39,087,586 probably null Het
Pramef17 C A 4: 143,993,245 L183F probably damaging Het
Rgsl1 T A 1: 153,826,202 T169S possibly damaging Het
Rnf38 T C 4: 44,152,529 R12G probably damaging Het
Slc9c1 T C 16: 45,543,261 probably benign Het
Slpi T C 2: 164,355,447 probably benign Het
Snx17 G A 5: 31,196,011 V165I probably benign Het
Tnfaip3 A G 10: 19,004,609 V570A probably benign Het
Vmn1r63 A G 7: 5,803,351 M94T probably benign Het
Vmn2r95 A G 17: 18,452,313 I771V probably benign Het
Wiz A G 17: 32,356,558 V868A probably benign Het
Other mutations in Cyp2b9
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00901:Cyp2b9 APN 7 26198505 missense probably damaging 0.99
IGL01133:Cyp2b9 APN 7 26210235 missense probably damaging 1.00
IGL01331:Cyp2b9 APN 7 26187715 missense probably damaging 0.99
IGL02281:Cyp2b9 APN 7 26201104 missense probably damaging 0.99
IGL02502:Cyp2b9 APN 7 26187814 critical splice donor site probably null
IGL02713:Cyp2b9 APN 7 26173520 missense probably benign 0.12
IGL03307:Cyp2b9 APN 7 26199051 missense probably benign 0.00
R0010:Cyp2b9 UTSW 7 26186753 splice site probably benign
R0025:Cyp2b9 UTSW 7 26200813 missense probably benign 0.09
R0040:Cyp2b9 UTSW 7 26173474 missense possibly damaging 0.68
R0184:Cyp2b9 UTSW 7 26187007 nonsense probably null
R0370:Cyp2b9 UTSW 7 26210106 missense probably damaging 1.00
R1595:Cyp2b9 UTSW 7 26200907 missense possibly damaging 0.72
R1751:Cyp2b9 UTSW 7 26186675 missense probably benign 0.05
R1835:Cyp2b9 UTSW 7 26200783 missense probably benign
R1879:Cyp2b9 UTSW 7 26198569 missense probably damaging 0.99
R2256:Cyp2b9 UTSW 7 26173605 critical splice donor site probably null
R2257:Cyp2b9 UTSW 7 26173605 critical splice donor site probably null
R2418:Cyp2b9 UTSW 7 26186707 missense probably benign 0.00
R3420:Cyp2b9 UTSW 7 26210103 missense probably damaging 1.00
R4088:Cyp2b9 UTSW 7 26173456 missense probably damaging 0.99
R4412:Cyp2b9 UTSW 7 26198443 missense probably damaging 1.00
R4495:Cyp2b9 UTSW 7 26200755 missense probably benign 0.00
R4615:Cyp2b9 UTSW 7 26201125 missense probably damaging 1.00
R5375:Cyp2b9 UTSW 7 26187742 missense probably damaging 1.00
R5426:Cyp2b9 UTSW 7 26187655 missense probably benign
R5862:Cyp2b9 UTSW 7 26187807 missense probably benign 0.01
R6237:Cyp2b9 UTSW 7 26173574 missense probably benign 0.02
R6445:Cyp2b9 UTSW 7 26186987 missense probably benign 0.13
R6992:Cyp2b9 UTSW 7 26201139 missense probably benign 0.00
R7515:Cyp2b9 UTSW 7 26199171 missense probably damaging 1.00
R7654:Cyp2b9 UTSW 7 26186942 missense possibly damaging 0.72
R7816:Cyp2b9 UTSW 7 26201092 missense probably benign 0.01
R7850:Cyp2b9 UTSW 7 26186686 nonsense probably null
R7933:Cyp2b9 UTSW 7 26186686 nonsense probably null
Z1177:Cyp2b9 UTSW 7 26201163 missense probably benign 0.31
Posted On2016-08-02