Incidental Mutation 'IGL01548:Tle1'
| ID |
93175 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Tle1
|
| Ensembl Gene |
ENSMUSG00000008305 |
| Gene Name |
transducin-like enhancer of split 1 |
| Synonyms |
C230057C06Rik, Estm14, Grg1, Tle4l |
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.575)
|
| Stock # |
IGL01548
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
4 |
| Chromosomal Location |
72035379-72119156 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 72088955 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Proline
at position 96
(L96P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000102960
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000030095]
[ENSMUST00000072695]
[ENSMUST00000074216]
[ENSMUST00000102848]
[ENSMUST00000107337]
[ENSMUST00000137075]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000030095
AA Change: L96P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000030095
Gene: ENSMUSG00000008305
AA Change: L96P
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TLE_N
|
1 |
143 |
9.1e-77 |
PFAM |
|
low complexity region
|
155 |
183 |
N/A |
INTRINSIC |
|
low complexity region
|
240 |
255 |
N/A |
INTRINSIC |
|
low complexity region
|
265 |
276 |
N/A |
INTRINSIC |
|
low complexity region
|
292 |
314 |
N/A |
INTRINSIC |
|
low complexity region
|
411 |
422 |
N/A |
INTRINSIC |
|
WD40
|
484 |
521 |
4.18e-2 |
SMART |
|
WD40
|
527 |
568 |
1.03e-1 |
SMART |
|
WD40
|
573 |
612 |
9.38e-5 |
SMART |
|
WD40
|
615 |
654 |
1.14e-8 |
SMART |
|
WD40
|
657 |
695 |
3.07e1 |
SMART |
|
WD40
|
697 |
736 |
8.96e-2 |
SMART |
|
WD40
|
737 |
777 |
4.14e-1 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000072695
AA Change: L96P
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000072481
Gene: ENSMUSG00000008305
AA Change: L96P
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TLE_N
|
1 |
136 |
2.6e-78 |
PFAM |
|
low complexity region
|
145 |
173 |
N/A |
INTRINSIC |
|
low complexity region
|
230 |
245 |
N/A |
INTRINSIC |
|
low complexity region
|
255 |
266 |
N/A |
INTRINSIC |
|
low complexity region
|
282 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
401 |
412 |
N/A |
INTRINSIC |
|
WD40
|
474 |
511 |
4.18e-2 |
SMART |
|
WD40
|
517 |
558 |
1.03e-1 |
SMART |
|
WD40
|
563 |
602 |
9.38e-5 |
SMART |
|
WD40
|
605 |
644 |
1.14e-8 |
SMART |
|
WD40
|
647 |
685 |
3.07e1 |
SMART |
|
WD40
|
687 |
726 |
8.96e-2 |
SMART |
|
WD40
|
727 |
767 |
4.14e-1 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000074216
AA Change: L96P
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000073839
Gene: ENSMUSG00000008305
AA Change: L96P
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TLE_N
|
1 |
136 |
1.3e-78 |
PFAM |
|
low complexity region
|
145 |
173 |
N/A |
INTRINSIC |
|
low complexity region
|
230 |
245 |
N/A |
INTRINSIC |
|
low complexity region
|
255 |
266 |
N/A |
INTRINSIC |
|
low complexity region
|
282 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
401 |
412 |
N/A |
INTRINSIC |
|
WD40
|
474 |
511 |
4.18e-2 |
SMART |
|
WD40
|
517 |
558 |
1.03e-1 |
SMART |
|
WD40
|
563 |
602 |
9.38e-5 |
SMART |
|
WD40
|
605 |
644 |
1.14e-8 |
SMART |
|
WD40
|
647 |
685 |
3.07e1 |
SMART |
|
WD40
|
687 |
726 |
8.96e-2 |
SMART |
|
WD40
|
727 |
767 |
4.14e-1 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000102848
AA Change: L104P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000099912
Gene: ENSMUSG00000008305
AA Change: L104P
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TLE_N
|
1 |
144 |
1.3e-76 |
PFAM |
|
low complexity region
|
153 |
181 |
N/A |
INTRINSIC |
|
low complexity region
|
238 |
253 |
N/A |
INTRINSIC |
|
low complexity region
|
263 |
274 |
N/A |
INTRINSIC |
|
low complexity region
|
290 |
312 |
N/A |
INTRINSIC |
|
low complexity region
|
408 |
419 |
N/A |
INTRINSIC |
|
WD40
|
481 |
518 |
4.18e-2 |
SMART |
|
WD40
|
524 |
565 |
1.03e-1 |
SMART |
|
WD40
|
570 |
609 |
9.38e-5 |
SMART |
|
WD40
|
612 |
651 |
1.14e-8 |
SMART |
|
WD40
|
654 |
692 |
3.07e1 |
SMART |
|
WD40
|
694 |
733 |
8.96e-2 |
SMART |
|
WD40
|
734 |
774 |
4.14e-1 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000107337
AA Change: L96P
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000102960
Gene: ENSMUSG00000008305
AA Change: L96P
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TLE_N
|
1 |
136 |
7.2e-80 |
PFAM |
|
low complexity region
|
145 |
173 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000132550
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000134225
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000137075
AA Change: L118P
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000118683
Gene: ENSMUSG00000008305
AA Change: L118P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
5 |
17 |
N/A |
INTRINSIC |
|
Pfam:TLE_N
|
22 |
158 |
4.2e-77 |
PFAM |
|
low complexity region
|
167 |
195 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000142137
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 76 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acot3 |
C |
T |
12: 84,103,863 (GRCm39) |
T224I |
probably benign |
Het |
| Adamts18 |
C |
T |
8: 114,490,931 (GRCm39) |
G512E |
probably damaging |
Het |
| Atp4b |
A |
G |
8: 13,439,679 (GRCm39) |
I181T |
probably damaging |
Het |
| Bcl11a |
A |
G |
11: 24,113,346 (GRCm39) |
I230V |
probably benign |
Het |
| Cenpj |
C |
A |
14: 56,769,776 (GRCm39) |
V1138L |
probably benign |
Het |
| Cep78 |
A |
G |
19: 15,958,564 (GRCm39) |
|
probably benign |
Het |
| Clec2j |
T |
A |
6: 128,632,941 (GRCm39) |
|
noncoding transcript |
Het |
| Col5a3 |
T |
C |
9: 20,714,296 (GRCm39) |
|
probably benign |
Het |
| Cpne6 |
A |
T |
14: 55,750,183 (GRCm39) |
T105S |
probably damaging |
Het |
| Csmd1 |
A |
T |
8: 16,338,660 (GRCm39) |
Y482* |
probably null |
Het |
| Ctrl |
C |
A |
8: 106,659,890 (GRCm39) |
|
probably benign |
Het |
| Dhcr24 |
T |
A |
4: 106,431,068 (GRCm39) |
C252* |
probably null |
Het |
| Dnaaf9 |
T |
C |
2: 130,656,179 (GRCm39) |
N110D |
probably damaging |
Het |
| Dnah17 |
G |
A |
11: 117,989,438 (GRCm39) |
P1261S |
probably benign |
Het |
| Dnai2 |
T |
C |
11: 114,643,768 (GRCm39) |
L466P |
probably damaging |
Het |
| Dync2h1 |
A |
T |
9: 7,071,922 (GRCm39) |
F3036Y |
probably damaging |
Het |
| Eef1akmt2 |
A |
C |
7: 132,433,134 (GRCm39) |
S191A |
probably damaging |
Het |
| Fat4 |
G |
A |
3: 39,063,406 (GRCm39) |
C4454Y |
probably damaging |
Het |
| Fat4 |
T |
C |
3: 38,941,907 (GRCm39) |
S267P |
probably damaging |
Het |
| Frrs1 |
T |
C |
3: 116,678,834 (GRCm39) |
C219R |
probably damaging |
Het |
| Gabra6 |
T |
A |
11: 42,207,850 (GRCm39) |
Q207L |
probably damaging |
Het |
| Gm19668 |
A |
T |
10: 77,634,242 (GRCm39) |
C242* |
probably null |
Het |
| Gm2840 |
G |
A |
5: 96,322,136 (GRCm39) |
|
noncoding transcript |
Het |
| Gmcl1p1 |
G |
A |
X: 3,078,226 (GRCm39) |
G423S |
probably benign |
Het |
| Golim4 |
C |
T |
3: 75,815,432 (GRCm39) |
|
probably null |
Het |
| Gucy1b1 |
G |
T |
3: 81,942,169 (GRCm39) |
T530K |
probably damaging |
Het |
| Hacl1 |
A |
T |
14: 31,362,553 (GRCm39) |
D31E |
possibly damaging |
Het |
| Hectd4 |
A |
G |
5: 121,502,723 (GRCm39) |
T4276A |
possibly damaging |
Het |
| Henmt1 |
T |
C |
3: 108,850,095 (GRCm39) |
I26T |
probably damaging |
Het |
| Hspa1l |
G |
A |
17: 35,197,367 (GRCm39) |
A469T |
probably damaging |
Het |
| Htra3 |
T |
A |
5: 35,821,420 (GRCm39) |
|
probably null |
Het |
| Lrrc28 |
C |
A |
7: 67,278,042 (GRCm39) |
|
probably null |
Het |
| Mfhas1 |
T |
C |
8: 36,057,613 (GRCm39) |
L696P |
probably damaging |
Het |
| Mios |
A |
G |
6: 8,234,252 (GRCm39) |
K808E |
possibly damaging |
Het |
| Mtnr1b |
A |
G |
9: 15,774,496 (GRCm39) |
Y188H |
probably damaging |
Het |
| Myom1 |
A |
G |
17: 71,408,215 (GRCm39) |
|
probably benign |
Het |
| Naca |
A |
T |
10: 127,876,773 (GRCm39) |
|
probably benign |
Het |
| Nckap1l |
T |
A |
15: 103,371,147 (GRCm39) |
V213D |
probably benign |
Het |
| Ndufa6 |
C |
T |
15: 82,238,282 (GRCm39) |
V50M |
possibly damaging |
Het |
| Or4c35 |
T |
A |
2: 89,808,883 (GRCm39) |
F254I |
possibly damaging |
Het |
| Or5b111 |
A |
G |
19: 13,291,350 (GRCm39) |
F100L |
possibly damaging |
Het |
| Or5g23 |
A |
G |
2: 85,439,105 (GRCm39) |
W50R |
probably benign |
Het |
| Or8b56 |
A |
G |
9: 38,739,646 (GRCm39) |
T220A |
probably benign |
Het |
| Or8k53 |
T |
A |
2: 86,178,077 (GRCm39) |
Y11F |
possibly damaging |
Het |
| Osbpl1a |
T |
C |
18: 12,896,632 (GRCm39) |
Y311C |
probably damaging |
Het |
| Parp11 |
A |
C |
6: 127,468,562 (GRCm39) |
Y204S |
probably damaging |
Het |
| Pla2g4a |
A |
G |
1: 149,808,407 (GRCm39) |
|
probably null |
Het |
| Plec |
T |
C |
15: 76,073,458 (GRCm39) |
R519G |
probably benign |
Het |
| Ppp2r5c |
T |
A |
12: 110,534,261 (GRCm39) |
Y375N |
probably benign |
Het |
| Prss35 |
C |
A |
9: 86,637,327 (GRCm39) |
S32R |
probably benign |
Het |
| Prss57 |
C |
T |
10: 79,621,581 (GRCm39) |
|
probably benign |
Het |
| Ptprc |
A |
C |
1: 138,027,219 (GRCm39) |
|
probably null |
Het |
| Rims1 |
A |
G |
1: 22,577,683 (GRCm39) |
C188R |
probably damaging |
Het |
| Ripk4 |
G |
T |
16: 97,552,696 (GRCm39) |
Y144* |
probably null |
Het |
| Rpgrip1 |
A |
T |
14: 52,363,728 (GRCm39) |
|
probably benign |
Het |
| Rps6ka4 |
A |
G |
19: 6,809,691 (GRCm39) |
V378A |
probably benign |
Het |
| Rtf1 |
A |
G |
2: 119,542,589 (GRCm39) |
K298E |
probably benign |
Het |
| Sdk1 |
T |
C |
5: 142,071,520 (GRCm39) |
F1237L |
possibly damaging |
Het |
| Slc40a1 |
T |
C |
1: 45,948,652 (GRCm39) |
K543E |
probably benign |
Het |
| Slco1a8 |
A |
G |
6: 141,938,238 (GRCm39) |
I227T |
possibly damaging |
Het |
| Sorcs3 |
A |
T |
19: 48,782,607 (GRCm39) |
I1041F |
possibly damaging |
Het |
| Spata31e4 |
A |
G |
13: 50,854,414 (GRCm39) |
T91A |
probably benign |
Het |
| Spata31f3 |
T |
C |
4: 42,868,564 (GRCm39) |
E353G |
probably benign |
Het |
| Taok3 |
T |
C |
5: 117,410,262 (GRCm39) |
M818T |
probably benign |
Het |
| Tas2r119 |
T |
A |
15: 32,178,123 (GRCm39) |
F230I |
probably damaging |
Het |
| Tbc1d8 |
T |
C |
1: 39,420,385 (GRCm39) |
D716G |
probably damaging |
Het |
| Tfg |
A |
G |
16: 56,521,465 (GRCm39) |
S58P |
probably damaging |
Het |
| Thnsl1 |
A |
G |
2: 21,217,943 (GRCm39) |
I45V |
probably damaging |
Het |
| Tmem260 |
A |
C |
14: 48,717,782 (GRCm39) |
S276R |
possibly damaging |
Het |
| Utp20 |
A |
G |
10: 88,600,643 (GRCm39) |
S24P |
probably damaging |
Het |
| Vcam1 |
T |
C |
3: 115,909,600 (GRCm39) |
I576V |
probably benign |
Het |
| Vmn1r27 |
G |
T |
6: 58,192,538 (GRCm39) |
N105K |
probably benign |
Het |
| Vmn2r12 |
A |
C |
5: 109,240,893 (GRCm39) |
Y73* |
probably null |
Het |
| Vmn2r86 |
T |
C |
10: 130,282,151 (GRCm39) |
I822V |
probably benign |
Het |
| Wdr6 |
C |
T |
9: 108,452,096 (GRCm39) |
V596I |
possibly damaging |
Het |
| Zfp946 |
A |
T |
17: 22,673,643 (GRCm39) |
K132N |
possibly damaging |
Het |
|
| Other mutations in Tle1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00420:Tle1
|
APN |
4 |
72,087,355 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL00972:Tle1
|
APN |
4 |
72,040,637 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01737:Tle1
|
APN |
4 |
72,116,058 (GRCm39) |
splice site |
probably benign |
|
|
IGL01798:Tle1
|
APN |
4 |
72,055,385 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01943:Tle1
|
APN |
4 |
72,040,639 (GRCm39) |
missense |
probably damaging |
1.00 |
|
BB006:Tle1
|
UTSW |
4 |
72,118,239 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
BB016:Tle1
|
UTSW |
4 |
72,118,239 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
PIT4515001:Tle1
|
UTSW |
4 |
72,117,556 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R0140:Tle1
|
UTSW |
4 |
72,038,422 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0544:Tle1
|
UTSW |
4 |
72,043,227 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0603:Tle1
|
UTSW |
4 |
72,036,584 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0729:Tle1
|
UTSW |
4 |
72,044,679 (GRCm39) |
splice site |
probably benign |
|
|
R0786:Tle1
|
UTSW |
4 |
72,117,598 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0939:Tle1
|
UTSW |
4 |
72,036,771 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1297:Tle1
|
UTSW |
4 |
72,043,075 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1465:Tle1
|
UTSW |
4 |
72,058,068 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1465:Tle1
|
UTSW |
4 |
72,058,068 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1512:Tle1
|
UTSW |
4 |
72,059,495 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1967:Tle1
|
UTSW |
4 |
72,038,463 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2218:Tle1
|
UTSW |
4 |
72,117,556 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R3713:Tle1
|
UTSW |
4 |
72,044,659 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R4367:Tle1
|
UTSW |
4 |
72,036,400 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R4379:Tle1
|
UTSW |
4 |
72,036,400 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R4380:Tle1
|
UTSW |
4 |
72,036,400 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R4655:Tle1
|
UTSW |
4 |
72,063,581 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R4662:Tle1
|
UTSW |
4 |
72,055,335 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4731:Tle1
|
UTSW |
4 |
72,043,256 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R4732:Tle1
|
UTSW |
4 |
72,043,256 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R4733:Tle1
|
UTSW |
4 |
72,043,256 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R4812:Tle1
|
UTSW |
4 |
72,063,591 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5066:Tle1
|
UTSW |
4 |
72,076,504 (GRCm39) |
missense |
probably benign |
0.24 |
|
R5288:Tle1
|
UTSW |
4 |
72,060,081 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5386:Tle1
|
UTSW |
4 |
72,060,081 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5405:Tle1
|
UTSW |
4 |
72,057,208 (GRCm39) |
intron |
probably benign |
|
|
R5579:Tle1
|
UTSW |
4 |
72,058,045 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5590:Tle1
|
UTSW |
4 |
72,043,208 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R5762:Tle1
|
UTSW |
4 |
72,038,372 (GRCm39) |
splice site |
probably null |
|
|
R6617:Tle1
|
UTSW |
4 |
72,059,517 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6750:Tle1
|
UTSW |
4 |
72,040,687 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7077:Tle1
|
UTSW |
4 |
72,076,612 (GRCm39) |
missense |
probably benign |
0.25 |
|
R7153:Tle1
|
UTSW |
4 |
72,057,298 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7156:Tle1
|
UTSW |
4 |
72,088,953 (GRCm39) |
missense |
probably benign |
0.15 |
|
R7266:Tle1
|
UTSW |
4 |
72,057,924 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7316:Tle1
|
UTSW |
4 |
72,036,529 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7478:Tle1
|
UTSW |
4 |
72,055,349 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7523:Tle1
|
UTSW |
4 |
72,063,655 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7736:Tle1
|
UTSW |
4 |
72,117,571 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7862:Tle1
|
UTSW |
4 |
72,117,552 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7863:Tle1
|
UTSW |
4 |
72,059,529 (GRCm39) |
missense |
probably null |
0.68 |
|
R7929:Tle1
|
UTSW |
4 |
72,118,239 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R8074:Tle1
|
UTSW |
4 |
72,057,216 (GRCm39) |
frame shift |
probably null |
|
|
R8233:Tle1
|
UTSW |
4 |
72,043,181 (GRCm39) |
missense |
probably benign |
0.11 |
|
R8315:Tle1
|
UTSW |
4 |
72,044,428 (GRCm39) |
nonsense |
probably null |
|
|
R8350:Tle1
|
UTSW |
4 |
72,057,203 (GRCm39) |
intron |
probably benign |
|
|
R8494:Tle1
|
UTSW |
4 |
72,043,241 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8512:Tle1
|
UTSW |
4 |
72,040,670 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R8919:Tle1
|
UTSW |
4 |
72,076,525 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9171:Tle1
|
UTSW |
4 |
72,043,232 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R9192:Tle1
|
UTSW |
4 |
72,036,753 (GRCm39) |
missense |
probably benign |
0.12 |
|
R9391:Tle1
|
UTSW |
4 |
72,116,159 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9452:Tle1
|
UTSW |
4 |
72,040,596 (GRCm39) |
missense |
probably benign |
0.41 |
|
R9481:Tle1
|
UTSW |
4 |
72,044,504 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9497:Tle1
|
UTSW |
4 |
72,071,135 (GRCm39) |
critical splice acceptor site |
probably benign |
|
|
| Posted On |
2013-12-09 |
Incidental Mutation