Incidental Mutation 'R1677:Ncoa6'
| ID |
188156 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ncoa6
|
| Ensembl Gene |
ENSMUSG00000038369 |
| Gene Name |
nuclear receptor coactivator 6 |
| Synonyms |
ASC-2, RAP250, NRC, AIB3, ASC2, PRIP |
| MMRRC Submission |
039713-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R1677 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
155232585-155315741 bp(-) (GRCm39) |
| Type of Mutation |
unclassified |
| DNA Base Change (assembly) |
T to C
at 155244584 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000118113
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000043126]
[ENSMUST00000109670]
[ENSMUST00000123293]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000043126
|
| SMART Domains |
Protein: ENSMUSP00000045386
Gene: ENSMUSG00000038369
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Nucleic_acid_bd
|
47 |
190 |
3.3e-55 |
PFAM |
|
coiled coil region
|
256 |
296 |
N/A |
INTRINSIC |
|
low complexity region
|
375 |
383 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
450 |
597 |
3.31e-5 |
PROSPERO |
|
low complexity region
|
615 |
630 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
636 |
793 |
3.31e-5 |
PROSPERO |
|
low complexity region
|
844 |
860 |
N/A |
INTRINSIC |
|
low complexity region
|
909 |
931 |
N/A |
INTRINSIC |
|
low complexity region
|
986 |
998 |
N/A |
INTRINSIC |
|
low complexity region
|
1002 |
1046 |
N/A |
INTRINSIC |
|
low complexity region
|
1126 |
1139 |
N/A |
INTRINSIC |
|
low complexity region
|
1258 |
1273 |
N/A |
INTRINSIC |
|
low complexity region
|
1328 |
1351 |
N/A |
INTRINSIC |
|
low complexity region
|
1543 |
1564 |
N/A |
INTRINSIC |
|
low complexity region
|
1578 |
1599 |
N/A |
INTRINSIC |
|
low complexity region
|
1607 |
1618 |
N/A |
INTRINSIC |
|
low complexity region
|
1808 |
1825 |
N/A |
INTRINSIC |
|
low complexity region
|
1894 |
1908 |
N/A |
INTRINSIC |
|
low complexity region
|
2043 |
2053 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000109670
|
| SMART Domains |
Protein: ENSMUSP00000105295
Gene: ENSMUSG00000038369
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Nucleic_acid_bd
|
45 |
195 |
3.6e-60 |
PFAM |
|
coiled coil region
|
256 |
296 |
N/A |
INTRINSIC |
|
low complexity region
|
375 |
383 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
450 |
597 |
3.31e-5 |
PROSPERO |
|
low complexity region
|
615 |
630 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
636 |
793 |
3.31e-5 |
PROSPERO |
|
low complexity region
|
844 |
860 |
N/A |
INTRINSIC |
|
low complexity region
|
909 |
931 |
N/A |
INTRINSIC |
|
low complexity region
|
986 |
998 |
N/A |
INTRINSIC |
|
low complexity region
|
1002 |
1046 |
N/A |
INTRINSIC |
|
low complexity region
|
1126 |
1139 |
N/A |
INTRINSIC |
|
low complexity region
|
1258 |
1273 |
N/A |
INTRINSIC |
|
low complexity region
|
1328 |
1351 |
N/A |
INTRINSIC |
|
low complexity region
|
1543 |
1564 |
N/A |
INTRINSIC |
|
low complexity region
|
1578 |
1599 |
N/A |
INTRINSIC |
|
low complexity region
|
1607 |
1618 |
N/A |
INTRINSIC |
|
low complexity region
|
1808 |
1825 |
N/A |
INTRINSIC |
|
low complexity region
|
1894 |
1908 |
N/A |
INTRINSIC |
|
low complexity region
|
2043 |
2053 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000123293
|
| SMART Domains |
Protein: ENSMUSP00000118113
Gene: ENSMUSG00000038369
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Nucleic_acid_bd
|
45 |
195 |
2.4e-60 |
PFAM |
|
coiled coil region
|
256 |
296 |
N/A |
INTRINSIC |
|
low complexity region
|
375 |
383 |
N/A |
INTRINSIC |
|
low complexity region
|
564 |
573 |
N/A |
INTRINSIC |
|
low complexity region
|
615 |
630 |
N/A |
INTRINSIC |
|
low complexity region
|
844 |
860 |
N/A |
INTRINSIC |
|
low complexity region
|
909 |
931 |
N/A |
INTRINSIC |
|
low complexity region
|
986 |
998 |
N/A |
INTRINSIC |
|
low complexity region
|
1002 |
1046 |
N/A |
INTRINSIC |
|
low complexity region
|
1126 |
1139 |
N/A |
INTRINSIC |
|
low complexity region
|
1258 |
1273 |
N/A |
INTRINSIC |
|
low complexity region
|
1328 |
1351 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000146942
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.3%
- 10x: 96.3%
- 20x: 92.6%
|
| Validation Efficiency |
100% (95/95) |
| MGI Phenotype |
PHENOTYPE: Homozygotes for targeted null mutations exhibit retarded embryonic growth and defects of the placenta, heart, liver, and nervous system. Mutants die around midgestation. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 90 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700093K21Rik |
A |
T |
11: 23,467,357 (GRCm39) |
M92K |
probably benign |
Het |
| 4931406C07Rik |
T |
C |
9: 15,212,660 (GRCm39) |
|
probably null |
Het |
| A430005L14Rik |
G |
A |
4: 154,045,357 (GRCm39) |
V129M |
probably damaging |
Het |
| Actg2 |
T |
C |
6: 83,499,801 (GRCm39) |
T150A |
possibly damaging |
Het |
| Actn1 |
A |
T |
12: 80,306,806 (GRCm39) |
D20E |
probably benign |
Het |
| Alcam |
C |
T |
16: 52,091,136 (GRCm39) |
E461K |
probably damaging |
Het |
| Anapc1 |
G |
A |
2: 128,518,128 (GRCm39) |
P242L |
probably benign |
Het |
| Ankrd49 |
A |
T |
9: 14,692,674 (GRCm39) |
D163E |
probably benign |
Het |
| Atp8b5 |
G |
A |
4: 43,372,903 (GRCm39) |
R1149Q |
possibly damaging |
Het |
| Cacnb3 |
G |
T |
15: 98,540,455 (GRCm39) |
V328F |
probably damaging |
Het |
| Camk4 |
T |
C |
18: 33,309,275 (GRCm39) |
I226T |
probably damaging |
Het |
| Ccdc148 |
T |
C |
2: 58,892,176 (GRCm39) |
D172G |
probably damaging |
Het |
| Cdh12 |
A |
G |
15: 21,520,491 (GRCm39) |
I319V |
probably damaging |
Het |
| Cenpc1 |
T |
C |
5: 86,209,857 (GRCm39) |
|
probably benign |
Het |
| Cfap69 |
A |
C |
5: 5,632,457 (GRCm39) |
N15K |
probably damaging |
Het |
| Ckap2l |
A |
C |
2: 129,127,087 (GRCm39) |
S364A |
possibly damaging |
Het |
| Clic6 |
G |
A |
16: 92,324,972 (GRCm39) |
G36R |
probably damaging |
Het |
| Col6a3 |
T |
C |
1: 90,749,583 (GRCm39) |
Y417C |
probably benign |
Het |
| Cstf3 |
T |
A |
2: 104,494,623 (GRCm39) |
|
probably benign |
Het |
| Cyp4f39 |
G |
A |
17: 32,711,304 (GRCm39) |
A484T |
probably benign |
Het |
| Dnah3 |
T |
C |
7: 119,527,963 (GRCm39) |
N3829D |
probably damaging |
Het |
| Dntt |
C |
A |
19: 41,017,923 (GRCm39) |
P16T |
probably benign |
Het |
| Dym |
T |
A |
18: 75,258,583 (GRCm39) |
I447N |
probably damaging |
Het |
| Elmo1 |
T |
C |
13: 20,773,841 (GRCm39) |
V617A |
probably benign |
Het |
| Elovl7 |
G |
A |
13: 108,419,160 (GRCm39) |
G264D |
probably damaging |
Het |
| Epha7 |
T |
A |
4: 28,947,571 (GRCm39) |
Y610* |
probably null |
Het |
| Fn1 |
T |
C |
1: 71,636,814 (GRCm39) |
I178V |
probably benign |
Het |
| Fndc9 |
T |
C |
11: 46,129,152 (GRCm39) |
Y224H |
probably benign |
Het |
| Gad1 |
T |
C |
2: 70,404,521 (GRCm39) |
V137A |
probably damaging |
Het |
| Gapvd1 |
A |
G |
2: 34,590,773 (GRCm39) |
|
probably null |
Het |
| Gbp11 |
C |
T |
5: 105,475,277 (GRCm39) |
C357Y |
probably damaging |
Het |
| Gcc1 |
G |
A |
6: 28,419,163 (GRCm39) |
A390V |
probably benign |
Het |
| Gm6811 |
A |
G |
17: 21,314,185 (GRCm39) |
|
noncoding transcript |
Het |
| Htt |
A |
T |
5: 34,985,918 (GRCm39) |
D1063V |
probably damaging |
Het |
| Igfn1 |
C |
T |
1: 135,898,839 (GRCm39) |
A576T |
probably damaging |
Het |
| Il12rb2 |
T |
C |
6: 67,280,485 (GRCm39) |
Y240C |
probably damaging |
Het |
| Itga3 |
T |
C |
11: 94,946,585 (GRCm39) |
D747G |
probably damaging |
Het |
| Kcnip2 |
A |
C |
19: 45,782,979 (GRCm39) |
D134E |
probably damaging |
Het |
| Kif2b |
C |
A |
11: 91,466,798 (GRCm39) |
R495I |
probably damaging |
Het |
| Lef1 |
T |
C |
3: 130,993,938 (GRCm39) |
|
probably benign |
Het |
| Lias |
C |
T |
5: 65,548,981 (GRCm39) |
R4C |
probably damaging |
Het |
| Lpcat2 |
T |
C |
8: 93,591,560 (GRCm39) |
V68A |
probably benign |
Het |
| Lrrc37 |
A |
T |
11: 103,505,768 (GRCm39) |
S2067T |
probably benign |
Het |
| Lrrc8e |
A |
T |
8: 4,284,190 (GRCm39) |
K138N |
probably damaging |
Het |
| Map4k5 |
G |
A |
12: 69,852,082 (GRCm39) |
H767Y |
probably benign |
Het |
| Mga |
C |
A |
2: 119,791,333 (GRCm39) |
T2406K |
possibly damaging |
Het |
| Mtx1 |
A |
T |
3: 89,116,648 (GRCm39) |
S418T |
probably benign |
Het |
| Myh7 |
C |
T |
14: 55,224,973 (GRCm39) |
M531I |
probably benign |
Het |
| Myorg |
C |
T |
4: 41,497,947 (GRCm39) |
R561H |
probably benign |
Het |
| Ncaph2 |
T |
A |
15: 89,255,427 (GRCm39) |
M555K |
probably damaging |
Het |
| Nckap1 |
C |
T |
2: 80,348,286 (GRCm39) |
S889N |
probably benign |
Het |
| Nrp2 |
A |
G |
1: 62,822,479 (GRCm39) |
S691G |
probably benign |
Het |
| Odad2 |
T |
C |
18: 7,222,554 (GRCm39) |
T572A |
probably benign |
Het |
| Odf2l |
A |
T |
3: 144,845,543 (GRCm39) |
|
probably null |
Het |
| Or5aq6 |
T |
A |
2: 86,923,081 (GRCm39) |
H220L |
probably benign |
Het |
| Pcdh20 |
A |
G |
14: 88,705,410 (GRCm39) |
V630A |
probably damaging |
Het |
| Pebp4 |
T |
C |
14: 70,285,923 (GRCm39) |
|
probably null |
Het |
| Ppfia3 |
T |
A |
7: 45,006,090 (GRCm39) |
M301L |
probably benign |
Het |
| Ppp1r21 |
C |
A |
17: 88,858,097 (GRCm39) |
Q203K |
probably benign |
Het |
| Prr23a1 |
T |
C |
9: 98,725,406 (GRCm39) |
V256A |
probably benign |
Het |
| Rbfox1 |
A |
G |
16: 7,110,091 (GRCm39) |
R150G |
possibly damaging |
Het |
| Rnps1-ps |
A |
T |
6: 7,982,943 (GRCm39) |
|
noncoding transcript |
Het |
| Robo3 |
T |
C |
9: 37,329,005 (GRCm39) |
R1238G |
possibly damaging |
Het |
| Rp9 |
T |
G |
9: 22,365,097 (GRCm39) |
Q35P |
probably damaging |
Het |
| Rsrc1 |
C |
A |
3: 67,262,808 (GRCm39) |
A254E |
probably damaging |
Het |
| Shtn1 |
T |
A |
19: 58,998,222 (GRCm39) |
K390N |
probably damaging |
Het |
| Sidt2 |
C |
T |
9: 45,864,517 (GRCm39) |
V71I |
probably benign |
Het |
| Sirt7 |
A |
G |
11: 120,515,365 (GRCm39) |
V97A |
possibly damaging |
Het |
| Slc14a2 |
A |
G |
18: 78,206,419 (GRCm39) |
S466P |
probably benign |
Het |
| Slc2a10 |
T |
A |
2: 165,357,361 (GRCm39) |
D340E |
probably benign |
Het |
| Slc36a2 |
A |
C |
11: 55,075,735 (GRCm39) |
N17K |
probably benign |
Het |
| Slc4a10 |
A |
C |
2: 62,155,071 (GRCm39) |
N1086T |
probably benign |
Het |
| Sptb |
T |
C |
12: 76,676,423 (GRCm39) |
D177G |
probably damaging |
Het |
| Srpk2 |
A |
T |
5: 23,730,748 (GRCm39) |
|
probably null |
Het |
| Sucla2 |
T |
G |
14: 73,830,121 (GRCm39) |
V386G |
probably damaging |
Het |
| Susd1 |
G |
T |
4: 59,424,089 (GRCm39) |
N45K |
possibly damaging |
Het |
| Tbxas1 |
T |
C |
6: 38,994,822 (GRCm39) |
|
probably benign |
Het |
| Topors |
C |
T |
4: 40,261,776 (GRCm39) |
E503K |
probably damaging |
Het |
| Trpv5 |
T |
C |
6: 41,634,731 (GRCm39) |
R533G |
probably benign |
Het |
| Tshr |
A |
G |
12: 91,504,115 (GRCm39) |
H351R |
possibly damaging |
Het |
| Ube2f |
G |
A |
1: 91,203,037 (GRCm39) |
V94M |
probably damaging |
Het |
| Ugdh |
A |
G |
5: 65,580,521 (GRCm39) |
S216P |
probably damaging |
Het |
| Unc45b |
T |
A |
11: 82,802,531 (GRCm39) |
|
probably null |
Het |
| Vmn1r226 |
A |
G |
17: 20,908,335 (GRCm39) |
E189G |
probably damaging |
Het |
| Xrcc6 |
T |
G |
15: 81,913,900 (GRCm39) |
D75E |
probably benign |
Het |
| Ypel1 |
A |
G |
16: 16,921,474 (GRCm39) |
L70P |
probably damaging |
Het |
| Zcwpw1 |
A |
T |
5: 137,795,022 (GRCm39) |
R73W |
probably damaging |
Het |
| Zfp219 |
T |
C |
14: 52,246,512 (GRCm39) |
E160G |
probably damaging |
Het |
| Zfp804b |
G |
T |
5: 7,229,533 (GRCm39) |
|
probably benign |
Het |
| Zscan22 |
C |
A |
7: 12,640,730 (GRCm39) |
P325T |
probably damaging |
Het |
|
| Other mutations in Ncoa6 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00484:Ncoa6
|
APN |
2 |
155,248,128 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00849:Ncoa6
|
APN |
2 |
155,263,608 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL00933:Ncoa6
|
APN |
2 |
155,257,317 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00981:Ncoa6
|
APN |
2 |
155,248,099 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01420:Ncoa6
|
APN |
2 |
155,249,507 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02160:Ncoa6
|
APN |
2 |
155,263,003 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
IGL03049:Ncoa6
|
APN |
2 |
155,260,934 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03194:Ncoa6
|
APN |
2 |
155,257,788 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL03269:Ncoa6
|
APN |
2 |
155,248,409 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL03299:Ncoa6
|
APN |
2 |
155,249,207 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL03306:Ncoa6
|
APN |
2 |
155,247,427 (GRCm39) |
missense |
probably benign |
0.30 |
|
alcoa
|
UTSW |
2 |
155,244,584 (GRCm39) |
unclassified |
probably benign |
|
|
Aluminum
|
UTSW |
2 |
155,241,613 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
balboa
|
UTSW |
2 |
155,248,869 (GRCm39) |
missense |
probably benign |
0.05 |
|
mauna_loa
|
UTSW |
2 |
155,257,147 (GRCm39) |
missense |
probably damaging |
0.99 |
|
PIT4466001:Ncoa6
|
UTSW |
2 |
155,247,577 (GRCm39) |
missense |
probably benign |
|
|
R0011:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0014:Ncoa6
|
UTSW |
2 |
155,279,963 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0079:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0080:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0081:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0164:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0166:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0172:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0173:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0245:Ncoa6
|
UTSW |
2 |
155,233,131 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0284:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0285:Ncoa6
|
UTSW |
2 |
155,257,621 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0285:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0288:Ncoa6
|
UTSW |
2 |
155,250,211 (GRCm39) |
frame shift |
probably null |
|
|
R0539:Ncoa6
|
UTSW |
2 |
155,257,617 (GRCm39) |
missense |
probably benign |
0.08 |
|
R0652:Ncoa6
|
UTSW |
2 |
155,233,131 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0781:Ncoa6
|
UTSW |
2 |
155,253,440 (GRCm39) |
splice site |
probably benign |
|
|
R1053:Ncoa6
|
UTSW |
2 |
155,275,960 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1110:Ncoa6
|
UTSW |
2 |
155,253,440 (GRCm39) |
splice site |
probably benign |
|
|
R1420:Ncoa6
|
UTSW |
2 |
155,263,073 (GRCm39) |
nonsense |
probably null |
|
|
R1521:Ncoa6
|
UTSW |
2 |
155,257,142 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R1541:Ncoa6
|
UTSW |
2 |
155,257,224 (GRCm39) |
missense |
probably benign |
0.35 |
|
R1858:Ncoa6
|
UTSW |
2 |
155,263,559 (GRCm39) |
missense |
probably benign |
0.13 |
|
R1954:Ncoa6
|
UTSW |
2 |
155,248,741 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1955:Ncoa6
|
UTSW |
2 |
155,248,741 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R2040:Ncoa6
|
UTSW |
2 |
155,248,000 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2087:Ncoa6
|
UTSW |
2 |
155,248,079 (GRCm39) |
nonsense |
probably null |
|
|
R2159:Ncoa6
|
UTSW |
2 |
155,249,633 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2278:Ncoa6
|
UTSW |
2 |
155,249,570 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R2696:Ncoa6
|
UTSW |
2 |
155,279,935 (GRCm39) |
missense |
probably benign |
0.45 |
|
R2891:Ncoa6
|
UTSW |
2 |
155,279,881 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R3618:Ncoa6
|
UTSW |
2 |
155,249,709 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R3747:Ncoa6
|
UTSW |
2 |
155,253,561 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3778:Ncoa6
|
UTSW |
2 |
155,263,115 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3784:Ncoa6
|
UTSW |
2 |
155,249,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3802:Ncoa6
|
UTSW |
2 |
155,247,484 (GRCm39) |
missense |
probably benign |
|
|
R3820:Ncoa6
|
UTSW |
2 |
155,248,858 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3821:Ncoa6
|
UTSW |
2 |
155,248,858 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3822:Ncoa6
|
UTSW |
2 |
155,248,858 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3870:Ncoa6
|
UTSW |
2 |
155,257,477 (GRCm39) |
splice site |
probably null |
|
|
R4037:Ncoa6
|
UTSW |
2 |
155,249,290 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4488:Ncoa6
|
UTSW |
2 |
155,249,396 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4719:Ncoa6
|
UTSW |
2 |
155,233,081 (GRCm39) |
unclassified |
probably benign |
|
|
R4732:Ncoa6
|
UTSW |
2 |
155,263,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4733:Ncoa6
|
UTSW |
2 |
155,263,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4829:Ncoa6
|
UTSW |
2 |
155,257,147 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4835:Ncoa6
|
UTSW |
2 |
155,249,053 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R4883:Ncoa6
|
UTSW |
2 |
155,248,687 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4967:Ncoa6
|
UTSW |
2 |
155,263,252 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R5021:Ncoa6
|
UTSW |
2 |
155,248,869 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5234:Ncoa6
|
UTSW |
2 |
155,279,933 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5356:Ncoa6
|
UTSW |
2 |
155,263,112 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5358:Ncoa6
|
UTSW |
2 |
155,248,907 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5375:Ncoa6
|
UTSW |
2 |
155,275,915 (GRCm39) |
missense |
probably benign |
0.16 |
|
R5412:Ncoa6
|
UTSW |
2 |
155,249,701 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5579:Ncoa6
|
UTSW |
2 |
155,248,597 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5618:Ncoa6
|
UTSW |
2 |
155,279,817 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R5641:Ncoa6
|
UTSW |
2 |
155,263,756 (GRCm39) |
missense |
probably benign |
0.22 |
|
R5757:Ncoa6
|
UTSW |
2 |
155,253,528 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5761:Ncoa6
|
UTSW |
2 |
155,250,061 (GRCm39) |
missense |
probably benign |
0.11 |
|
R5778:Ncoa6
|
UTSW |
2 |
155,248,688 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5852:Ncoa6
|
UTSW |
2 |
155,247,419 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R5940:Ncoa6
|
UTSW |
2 |
155,257,785 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6155:Ncoa6
|
UTSW |
2 |
155,249,368 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6374:Ncoa6
|
UTSW |
2 |
155,263,076 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6389:Ncoa6
|
UTSW |
2 |
155,237,736 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6669:Ncoa6
|
UTSW |
2 |
155,241,613 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7097:Ncoa6
|
UTSW |
2 |
155,279,983 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7385:Ncoa6
|
UTSW |
2 |
155,249,721 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7963:Ncoa6
|
UTSW |
2 |
155,247,916 (GRCm39) |
missense |
probably benign |
0.30 |
|
R8356:Ncoa6
|
UTSW |
2 |
155,248,172 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R8698:Ncoa6
|
UTSW |
2 |
155,257,041 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8859:Ncoa6
|
UTSW |
2 |
155,248,388 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R8870:Ncoa6
|
UTSW |
2 |
155,263,078 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9041:Ncoa6
|
UTSW |
2 |
155,257,450 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9062:Ncoa6
|
UTSW |
2 |
155,263,348 (GRCm39) |
missense |
probably benign |
0.42 |
|
R9088:Ncoa6
|
UTSW |
2 |
155,249,726 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9225:Ncoa6
|
UTSW |
2 |
155,249,441 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9445:Ncoa6
|
UTSW |
2 |
155,250,063 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9497:Ncoa6
|
UTSW |
2 |
155,248,238 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9514:Ncoa6
|
UTSW |
2 |
155,248,133 (GRCm39) |
missense |
probably benign |
0.19 |
|
R9656:Ncoa6
|
UTSW |
2 |
155,274,846 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9720:Ncoa6
|
UTSW |
2 |
155,250,304 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9732:Ncoa6
|
UTSW |
2 |
155,244,636 (GRCm39) |
missense |
probably damaging |
0.99 |
|
RF033:Ncoa6
|
UTSW |
2 |
155,263,651 (GRCm39) |
small deletion |
probably benign |
|
|
RF040:Ncoa6
|
UTSW |
2 |
155,263,651 (GRCm39) |
small deletion |
probably benign |
|
|
RF048:Ncoa6
|
UTSW |
2 |
155,263,632 (GRCm39) |
small deletion |
probably benign |
|
|
X0017:Ncoa6
|
UTSW |
2 |
155,248,460 (GRCm39) |
missense |
probably benign |
0.05 |
|
Z1176:Ncoa6
|
UTSW |
2 |
155,263,222 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1177:Ncoa6
|
UTSW |
2 |
155,263,138 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Ncoa6
|
UTSW |
2 |
155,248,062 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGCGAACTACTTAGCAGCCAGC -3'
(R):5'- AGCTTCAAGCCTGCAAGCATGG -3'
Sequencing Primer
(F):5'- TGAGCACAGAGATACCTTTCTTG -3'
(R):5'- TGCAAGCATGGCCTTCTAAG -3'
|
| Posted On |
2014-05-09 |
Incidental Mutation