Incidental Mutation 'R4841:Adamts6'
| ID |
371858 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Adamts6
|
| Ensembl Gene |
ENSMUSG00000046169 |
| Gene Name |
ADAM metallopeptidase with thrombospondin type 1 motif 6 |
| Synonyms |
b2b2029Clo, b2b2182Clo, b2b2187.1Clo, b2b1879.1Clo, A930019D11Rik, ADAM-TS6, b2b2228Clo |
| MMRRC Submission |
042454-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.831)
|
| Stock # |
R4841 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
13 |
| Chromosomal Location |
104424343-104633203 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 104449295 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 39
(D39G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000153194
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000065766]
[ENSMUST00000223562]
[ENSMUST00000224208]
[ENSMUST00000224303]
[ENSMUST00000224504]
[ENSMUST00000224742]
[ENSMUST00000224784]
|
| AlphaFold |
D3Z1A5 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000065766
AA Change: D235G
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000064570
Gene: ENSMUSG00000046169
AA Change: D235G
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
17 |
N/A |
INTRINSIC |
|
Pfam:Pep_M12B_propep
|
43 |
191 |
4.2e-40 |
PFAM |
|
Pfam:Reprolysin_5
|
248 |
443 |
3.8e-17 |
PFAM |
|
Pfam:Reprolysin_4
|
248 |
464 |
4.9e-12 |
PFAM |
|
Pfam:Reprolysin
|
250 |
468 |
1.6e-27 |
PFAM |
|
Pfam:Reprolysin_2
|
268 |
458 |
5.6e-15 |
PFAM |
|
Pfam:Reprolysin_3
|
272 |
414 |
2.6e-14 |
PFAM |
|
TSP1
|
561 |
613 |
3.98e-13 |
SMART |
|
Pfam:ADAM_spacer1
|
717 |
829 |
2.9e-41 |
PFAM |
|
TSP1
|
843 |
900 |
2.49e-5 |
SMART |
|
TSP1
|
902 |
960 |
2.87e-5 |
SMART |
|
TSP1
|
963 |
1018 |
1.36e-1 |
SMART |
|
TSP1
|
1021 |
1069 |
2.36e-6 |
SMART |
|
Pfam:PLAC
|
1083 |
1115 |
3.9e-12 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000223562
AA Change: D235G
PolyPhen 2
Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000224208
AA Change: D235G
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000224303
AA Change: D235G
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000224504
AA Change: D39G
PolyPhen 2
Score 0.004 (Sensitivity: 0.98; Specificity: 0.59)
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000224742
AA Change: D235G
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000224784
AA Change: D235G
PolyPhen 2
Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.5%
- 20x: 92.9%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. Expression of this gene may be regulated by the cytokine TNF-alpha. [provided by RefSeq, Mar 2016]
PHENOTYPE: Mice homozygous for induced mutations exhibit cardiovascular defects including double outlet right ventricle, ventricular septal defects and biventricular hypertrophy, and hydrops, thymus hypoplasia short snout and cleft palate. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(1) : Targeted(1)
|
| Other mutations in this stock |
Total: 89 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1600012H06Rik |
A |
T |
17: 15,164,001 (GRCm39) |
I43L |
possibly damaging |
Het |
| 4933427I04Rik |
T |
A |
4: 123,754,170 (GRCm39) |
M28K |
probably benign |
Het |
| A2m |
A |
T |
6: 121,623,803 (GRCm39) |
I390F |
probably benign |
Het |
| Abcc8 |
T |
C |
7: 45,800,252 (GRCm39) |
K510R |
probably damaging |
Het |
| Adgrl3 |
T |
C |
5: 81,942,118 (GRCm39) |
S1326P |
possibly damaging |
Het |
| Adgrv1 |
A |
G |
13: 81,651,120 (GRCm39) |
|
probably null |
Het |
| Ap3b2 |
G |
A |
7: 81,127,678 (GRCm39) |
A166V |
probably damaging |
Het |
| Bbox1 |
T |
A |
2: 110,134,084 (GRCm39) |
|
probably null |
Het |
| Bckdk |
A |
G |
7: 127,504,633 (GRCm39) |
|
probably null |
Het |
| Cand1 |
C |
A |
10: 119,049,451 (GRCm39) |
|
probably null |
Het |
| Capn5 |
T |
C |
7: 97,780,879 (GRCm39) |
|
probably null |
Het |
| Ccdc121rt2 |
A |
T |
5: 112,598,106 (GRCm39) |
K218* |
probably null |
Het |
| Cd209c |
G |
T |
8: 3,995,905 (GRCm39) |
R2S |
probably benign |
Het |
| Ces1g |
C |
T |
8: 94,060,323 (GRCm39) |
E99K |
probably benign |
Het |
| Cnmd |
A |
G |
14: 79,887,762 (GRCm39) |
I153T |
possibly damaging |
Het |
| Cntrob |
C |
G |
11: 69,206,220 (GRCm39) |
L315F |
possibly damaging |
Het |
| Cspg4b |
G |
A |
13: 113,502,724 (GRCm39) |
G143D |
probably benign |
Het |
| Ctdp1 |
A |
G |
18: 80,451,941 (GRCm39) |
S145P |
unknown |
Het |
| Dmrt2 |
G |
A |
19: 25,655,031 (GRCm39) |
G210D |
probably damaging |
Het |
| Dnajc16 |
A |
G |
4: 141,501,936 (GRCm39) |
F298S |
probably damaging |
Het |
| Dock5 |
T |
C |
14: 68,055,012 (GRCm39) |
D618G |
probably damaging |
Het |
| Drc3 |
G |
A |
11: 60,261,361 (GRCm39) |
A171T |
probably benign |
Het |
| Dspp |
A |
T |
5: 104,325,052 (GRCm39) |
S472C |
unknown |
Het |
| Dspp |
G |
T |
5: 104,325,053 (GRCm39) |
S472I |
unknown |
Het |
| Ecel1 |
A |
T |
1: 87,081,023 (GRCm39) |
N322K |
probably damaging |
Het |
| Eftud2 |
A |
G |
11: 102,745,640 (GRCm39) |
F362L |
probably damaging |
Het |
| Egfr |
C |
T |
11: 16,861,607 (GRCm39) |
H1129Y |
probably benign |
Het |
| Erich3 |
T |
A |
3: 154,410,480 (GRCm39) |
F112I |
possibly damaging |
Het |
| Fam107b |
T |
C |
2: 3,779,580 (GRCm39) |
L261S |
probably damaging |
Het |
| Fancd2 |
T |
C |
6: 113,539,391 (GRCm39) |
S239P |
probably damaging |
Het |
| Fbp2 |
C |
A |
13: 63,002,727 (GRCm39) |
Q108H |
probably benign |
Het |
| Fcgbpl1 |
T |
A |
7: 27,850,147 (GRCm39) |
C1198S |
probably damaging |
Het |
| Gask1b |
G |
A |
3: 79,843,912 (GRCm39) |
R377H |
probably damaging |
Het |
| Gipr |
C |
T |
7: 18,896,601 (GRCm39) |
R165H |
probably damaging |
Het |
| Gje1 |
C |
T |
10: 14,593,082 (GRCm39) |
G45R |
probably null |
Het |
| Gpat2 |
C |
G |
2: 127,275,887 (GRCm39) |
T555S |
probably benign |
Het |
| Grik3 |
C |
A |
4: 125,584,969 (GRCm39) |
N612K |
probably damaging |
Het |
| Iqcb1 |
A |
G |
16: 36,655,952 (GRCm39) |
E113G |
probably benign |
Het |
| Kat8 |
A |
G |
7: 127,524,366 (GRCm39) |
I415V |
probably benign |
Het |
| Kcnk10 |
A |
T |
12: 98,401,175 (GRCm39) |
M486K |
probably benign |
Het |
| Kif21b |
C |
A |
1: 136,072,958 (GRCm39) |
H119N |
probably damaging |
Het |
| Leng9 |
T |
C |
7: 4,152,385 (GRCm39) |
D97G |
probably damaging |
Het |
| Lrguk |
T |
C |
6: 34,069,802 (GRCm39) |
V559A |
probably damaging |
Het |
| Lrp1 |
G |
T |
10: 127,419,805 (GRCm39) |
R935S |
probably damaging |
Het |
| Lrrcc1 |
C |
A |
3: 14,627,571 (GRCm39) |
D503E |
probably benign |
Het |
| Mybph |
A |
T |
1: 134,126,233 (GRCm39) |
E349V |
probably damaging |
Het |
| Myzap |
A |
G |
9: 71,456,037 (GRCm39) |
S328P |
probably damaging |
Het |
| Nbeal1 |
T |
C |
1: 60,292,534 (GRCm39) |
L1062P |
probably damaging |
Het |
| Nepro |
G |
A |
16: 44,555,160 (GRCm39) |
S412N |
probably null |
Het |
| Nudt5 |
T |
C |
2: 5,869,239 (GRCm39) |
V155A |
probably benign |
Het |
| Or13a25 |
A |
T |
7: 140,247,502 (GRCm39) |
I94F |
probably damaging |
Het |
| Or4k51 |
C |
G |
2: 111,584,679 (GRCm39) |
F28L |
probably benign |
Het |
| Or5ae2 |
G |
T |
7: 84,506,328 (GRCm39) |
L250F |
probably damaging |
Het |
| Or6ae1 |
A |
G |
7: 139,742,602 (GRCm39) |
L87P |
possibly damaging |
Het |
| Osbpl3 |
T |
A |
6: 50,286,356 (GRCm39) |
N623I |
probably damaging |
Het |
| Pde4dip |
T |
A |
3: 97,700,844 (GRCm39) |
H220L |
probably damaging |
Het |
| Pde9a |
T |
A |
17: 31,662,135 (GRCm39) |
|
probably null |
Het |
| Pex16 |
T |
G |
2: 92,209,544 (GRCm39) |
|
probably null |
Het |
| Pnpla7 |
A |
G |
2: 24,870,064 (GRCm39) |
T15A |
probably benign |
Het |
| Polq |
G |
T |
16: 36,869,145 (GRCm39) |
|
probably null |
Het |
| Ppfia2 |
C |
T |
10: 106,690,818 (GRCm39) |
T553I |
probably benign |
Het |
| Rreb1 |
G |
A |
13: 38,100,502 (GRCm39) |
C211Y |
probably benign |
Het |
| Rundc3b |
A |
G |
5: 8,578,742 (GRCm39) |
L222P |
probably damaging |
Het |
| Ryr3 |
T |
C |
2: 112,478,718 (GRCm39) |
N4405S |
probably damaging |
Het |
| Sardh |
A |
G |
2: 27,081,967 (GRCm39) |
V853A |
probably benign |
Het |
| Scfd1 |
T |
C |
12: 51,436,109 (GRCm39) |
V86A |
probably damaging |
Het |
| Scube3 |
G |
A |
17: 28,383,097 (GRCm39) |
C425Y |
probably damaging |
Het |
| Sfta2 |
T |
C |
17: 35,960,773 (GRCm39) |
|
probably benign |
Het |
| Sh3d19 |
T |
C |
3: 86,031,049 (GRCm39) |
Y738H |
probably damaging |
Het |
| Shc2 |
T |
C |
10: 79,458,295 (GRCm39) |
R463G |
probably damaging |
Het |
| Slc4a10 |
T |
C |
2: 62,087,939 (GRCm39) |
V414A |
possibly damaging |
Het |
| Slc9a3 |
G |
T |
13: 74,313,956 (GRCm39) |
D755Y |
probably damaging |
Het |
| Snrpb2 |
C |
A |
2: 142,910,237 (GRCm39) |
F98L |
possibly damaging |
Het |
| Socs7 |
T |
A |
11: 97,267,829 (GRCm39) |
I320N |
possibly damaging |
Het |
| Speer2 |
A |
T |
16: 69,654,988 (GRCm39) |
M159K |
probably benign |
Het |
| Sppl2c |
A |
C |
11: 104,078,478 (GRCm39) |
H426P |
probably benign |
Het |
| Stxbp5 |
C |
A |
10: 9,638,635 (GRCm39) |
V1055L |
probably benign |
Het |
| Synpo |
A |
T |
18: 60,736,684 (GRCm39) |
S421T |
probably damaging |
Het |
| Taf6l |
A |
G |
19: 8,759,770 (GRCm39) |
V135A |
possibly damaging |
Het |
| Tafa5 |
C |
T |
15: 87,509,637 (GRCm39) |
|
probably benign |
Het |
| Trim58 |
G |
A |
11: 58,542,150 (GRCm39) |
G370E |
probably damaging |
Het |
| Tshz2 |
T |
A |
2: 169,728,167 (GRCm39) |
I452N |
probably damaging |
Het |
| Ttc41 |
C |
T |
10: 86,566,989 (GRCm39) |
R552C |
probably benign |
Het |
| Vit |
T |
C |
17: 78,909,308 (GRCm39) |
S252P |
probably benign |
Het |
| Vmn1r173 |
A |
T |
7: 23,402,361 (GRCm39) |
I199F |
probably damaging |
Het |
| Vmn2r114 |
T |
A |
17: 23,529,336 (GRCm39) |
R255S |
probably benign |
Het |
| Vmn2r17 |
A |
G |
5: 109,582,246 (GRCm39) |
N545S |
probably damaging |
Het |
| Zbtb44 |
T |
G |
9: 30,964,701 (GRCm39) |
V37G |
probably damaging |
Het |
| Zfp865 |
A |
G |
7: 5,034,640 (GRCm39) |
Y875C |
probably damaging |
Het |
|
| Other mutations in Adamts6 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00228:Adamts6
|
APN |
13 |
104,566,298 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
IGL00583:Adamts6
|
APN |
13 |
104,433,726 (GRCm39) |
nonsense |
probably null |
|
|
IGL01305:Adamts6
|
APN |
13 |
104,526,590 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01448:Adamts6
|
APN |
13 |
104,433,672 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01517:Adamts6
|
APN |
13 |
104,526,700 (GRCm39) |
splice site |
probably benign |
|
|
IGL01678:Adamts6
|
APN |
13 |
104,450,196 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01737:Adamts6
|
APN |
13 |
104,526,643 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02152:Adamts6
|
APN |
13 |
104,450,168 (GRCm39) |
missense |
probably null |
1.00 |
|
IGL02217:Adamts6
|
APN |
13 |
104,598,873 (GRCm39) |
splice site |
probably benign |
|
|
IGL02828:Adamts6
|
APN |
13 |
104,433,978 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03067:Adamts6
|
APN |
13 |
104,433,783 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03081:Adamts6
|
APN |
13 |
104,581,464 (GRCm39) |
utr 3 prime |
probably benign |
|
|
IGL03159:Adamts6
|
APN |
13 |
104,580,723 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03411:Adamts6
|
APN |
13 |
104,450,842 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
De_vito
|
UTSW |
13 |
104,483,900 (GRCm39) |
critical splice donor site |
probably null |
|
|
festinator
|
UTSW |
13 |
104,616,043 (GRCm39) |
missense |
probably damaging |
1.00 |
|
ANU22:Adamts6
|
UTSW |
13 |
104,526,590 (GRCm39) |
missense |
probably damaging |
1.00 |
|
P0007:Adamts6
|
UTSW |
13 |
104,433,999 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R0362:Adamts6
|
UTSW |
13 |
104,526,584 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0504:Adamts6
|
UTSW |
13 |
104,563,438 (GRCm39) |
splice site |
probably benign |
|
|
R0549:Adamts6
|
UTSW |
13 |
104,433,763 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R0566:Adamts6
|
UTSW |
13 |
104,581,435 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0703:Adamts6
|
UTSW |
13 |
104,489,355 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0799:Adamts6
|
UTSW |
13 |
104,450,779 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0838:Adamts6
|
UTSW |
13 |
104,550,297 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R1500:Adamts6
|
UTSW |
13 |
104,449,389 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1502:Adamts6
|
UTSW |
13 |
104,630,145 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1547:Adamts6
|
UTSW |
13 |
104,581,383 (GRCm39) |
missense |
probably benign |
0.26 |
|
R1619:Adamts6
|
UTSW |
13 |
104,449,285 (GRCm39) |
missense |
probably benign |
0.14 |
|
R1727:Adamts6
|
UTSW |
13 |
104,565,472 (GRCm39) |
splice site |
probably benign |
|
|
R1967:Adamts6
|
UTSW |
13 |
104,563,459 (GRCm39) |
nonsense |
probably null |
|
|
R2013:Adamts6
|
UTSW |
13 |
104,450,812 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2079:Adamts6
|
UTSW |
13 |
104,598,746 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2432:Adamts6
|
UTSW |
13 |
104,563,485 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3118:Adamts6
|
UTSW |
13 |
104,450,787 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R4125:Adamts6
|
UTSW |
13 |
104,449,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4274:Adamts6
|
UTSW |
13 |
104,450,787 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R4795:Adamts6
|
UTSW |
13 |
104,580,636 (GRCm39) |
nonsense |
probably null |
|
|
R4976:Adamts6
|
UTSW |
13 |
104,433,998 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5085:Adamts6
|
UTSW |
13 |
104,443,751 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5234:Adamts6
|
UTSW |
13 |
104,630,130 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5403:Adamts6
|
UTSW |
13 |
104,489,323 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R5753:Adamts6
|
UTSW |
13 |
104,483,858 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6027:Adamts6
|
UTSW |
13 |
104,616,043 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6187:Adamts6
|
UTSW |
13 |
104,433,933 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6229:Adamts6
|
UTSW |
13 |
104,483,900 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6243:Adamts6
|
UTSW |
13 |
104,450,809 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6257:Adamts6
|
UTSW |
13 |
104,598,790 (GRCm39) |
missense |
probably benign |
|
|
R6743:Adamts6
|
UTSW |
13 |
104,565,436 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6775:Adamts6
|
UTSW |
13 |
104,450,160 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7113:Adamts6
|
UTSW |
13 |
104,449,267 (GRCm39) |
missense |
probably benign |
|
|
R7351:Adamts6
|
UTSW |
13 |
104,526,620 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R7520:Adamts6
|
UTSW |
13 |
104,433,694 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7866:Adamts6
|
UTSW |
13 |
104,550,257 (GRCm39) |
nonsense |
probably null |
|
|
R8274:Adamts6
|
UTSW |
13 |
104,450,181 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8348:Adamts6
|
UTSW |
13 |
104,616,027 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8448:Adamts6
|
UTSW |
13 |
104,616,027 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8686:Adamts6
|
UTSW |
13 |
104,450,207 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8691:Adamts6
|
UTSW |
13 |
104,450,839 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8962:Adamts6
|
UTSW |
13 |
104,433,899 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8978:Adamts6
|
UTSW |
13 |
104,512,247 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9075:Adamts6
|
UTSW |
13 |
104,598,793 (GRCm39) |
missense |
probably benign |
|
|
R9080:Adamts6
|
UTSW |
13 |
104,449,427 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9152:Adamts6
|
UTSW |
13 |
104,613,275 (GRCm39) |
missense |
probably benign |
0.06 |
|
R9213:Adamts6
|
UTSW |
13 |
104,581,440 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9536:Adamts6
|
UTSW |
13 |
104,489,313 (GRCm39) |
missense |
probably benign |
0.07 |
|
R9674:Adamts6
|
UTSW |
13 |
104,563,448 (GRCm39) |
missense |
probably benign |
0.17 |
|
X0065:Adamts6
|
UTSW |
13 |
104,630,136 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATGAGGAATAGATACTGCAGACTCAC -3'
(R):5'- TTGTAGACTCAATCCCAAGCAG -3'
Sequencing Primer
(F):5'- CAGACTCACTGTTTTCAATCATCATG -3'
(R):5'- CTACCTTAATATAAAACACAG -3'
|
| Posted On |
2016-03-01 |
Incidental Mutation