Mutagenetix > Incidental Mutation

Incidental Mutation 'R5925:Unc79'

461804

Institutional Source

Beutler Lab

Gene Symbol

Unc79

Ensembl Gene

ENSMUSG00000021198

Gene Name

unc-79 homolog

Synonyms

9030205A07Rik, Mlca3

MMRRC Submission

044120-MU

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

R5925 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

102915118-103150324 bp(+) (GRCm39)

Type of Mutation

splice site (5 bp from exon)

DNA Base Change (assembly)

G to C at 103091989 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000136332 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000085079] [ENSMUST00000101099] [ENSMUST00000178076] [ENSMUST00000179002]

AlphaFold

Q0KK59

Predicted Effect

probably null
Transcript: ENSMUST00000085079

SMART Domains

Protein: ENSMUSP00000082156
Gene: ENSMUSG00000021198

Domain	Start	End	E-Value	Type
Pfam:UNC-79	1	469	3.1e-223	PFAM
low complexity region	732	737	N/A	INTRINSIC
low complexity region	846	862	N/A	INTRINSIC
low complexity region	968	977	N/A	INTRINSIC
low complexity region	1114	1125	N/A	INTRINSIC
low complexity region	1313	1325	N/A	INTRINSIC
low complexity region	1428	1440	N/A	INTRINSIC
low complexity region	1471	1476	N/A	INTRINSIC
low complexity region	1477	1489	N/A	INTRINSIC
low complexity region	1490	1504	N/A	INTRINSIC
low complexity region	1541	1556	N/A	INTRINSIC
low complexity region	1861	1870	N/A	INTRINSIC
low complexity region	2237	2246	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000101099

SMART Domains

Protein: ENSMUSP00000098659
Gene: ENSMUSG00000021198

Domain	Start	End	E-Value	Type
Pfam:UNC-79	113	646	1.2e-226	PFAM
low complexity region	909	914	N/A	INTRINSIC
low complexity region	1023	1039	N/A	INTRINSIC
low complexity region	1145	1154	N/A	INTRINSIC
low complexity region	1291	1302	N/A	INTRINSIC
low complexity region	1490	1502	N/A	INTRINSIC
low complexity region	1605	1617	N/A	INTRINSIC
low complexity region	1648	1653	N/A	INTRINSIC
low complexity region	1654	1666	N/A	INTRINSIC
low complexity region	1667	1681	N/A	INTRINSIC
low complexity region	1718	1733	N/A	INTRINSIC
low complexity region	1999	2008	N/A	INTRINSIC
low complexity region	2375	2384	N/A	INTRINSIC

Predicted Effect

probably null
Transcript: ENSMUST00000178076

SMART Domains

Protein: ENSMUSP00000136888
Gene: ENSMUSG00000021198

Domain	Start	End	E-Value	Type
Pfam:UNC-79	1	450	4.2e-213	PFAM
low complexity region	713	718	N/A	INTRINSIC
low complexity region	827	843	N/A	INTRINSIC
low complexity region	949	958	N/A	INTRINSIC
low complexity region	1117	1128	N/A	INTRINSIC
low complexity region	1316	1328	N/A	INTRINSIC
low complexity region	1431	1443	N/A	INTRINSIC
low complexity region	1474	1479	N/A	INTRINSIC
low complexity region	1480	1492	N/A	INTRINSIC
low complexity region	1493	1507	N/A	INTRINSIC
low complexity region	1544	1559	N/A	INTRINSIC
low complexity region	1864	1873	N/A	INTRINSIC
low complexity region	2240	2249	N/A	INTRINSIC

Predicted Effect

probably null
Transcript: ENSMUST00000179002

SMART Domains

Protein: ENSMUSP00000136332
Gene: ENSMUSG00000021198

Domain	Start	End	E-Value	Type
Pfam:UNC-79	60	593	1.3e-226	PFAM
low complexity region	856	861	N/A	INTRINSIC
low complexity region	970	986	N/A	INTRINSIC
low complexity region	1092	1101	N/A	INTRINSIC
low complexity region	1260	1271	N/A	INTRINSIC
low complexity region	1509	1521	N/A	INTRINSIC
low complexity region	1624	1636	N/A	INTRINSIC
low complexity region	1667	1672	N/A	INTRINSIC
low complexity region	1673	1685	N/A	INTRINSIC
low complexity region	1686	1700	N/A	INTRINSIC
low complexity region	1737	1752	N/A	INTRINSIC
low complexity region	2057	2066	N/A	INTRINSIC
low complexity region	2433	2442	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000183635

Coding Region Coverage

1x: 99.8%
3x: 99.4%
10x: 97.4%
20x: 91.8%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The NALCN channel is responsible for Na(+) leak currents. The protein encoded by this gene, along with UNC80, is an accessory subunit of the NALCN channel that contributes to the Ca(2+) sensitivity of the channel. [provided by RefSeq, Sep 2016]
PHENOTYPE: Homozygous mutation results in lethality within the first week after birth, mostly at P0 or P1. Pups fail to nurse and have no milk in stomachs resulting in weakness, inactivity and no weight gain. [provided by MGI curators]

Allele List at MGI

All alleles(2) : Targeted, knock-out(1) Chemically induced(1)

Other mutations in this stock

Total: 43 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
9130230L23Rik	C	T	5: 66,147,735 (GRCm39)	W16*	probably null	Het
Abca8a	T	C	11: 109,948,049 (GRCm39)	D985G	probably damaging	Het
Afp	T	A	5: 90,645,147 (GRCm39)	C188S	probably damaging	Het
Ank2	A	C	3: 126,726,612 (GRCm39)	L894R	probably benign	Het
Antxr1	A	G	6: 87,289,344 (GRCm39)	I60T	probably damaging	Het
Bltp2	T	C	11: 78,175,064 (GRCm39)	V1733A	probably benign	Het
Ccdc187	A	G	2: 26,183,593 (GRCm39)	S136P	probably benign	Het
Cep95	T	C	11: 106,703,227 (GRCm39)	S393P	probably benign	Het
Cyfip2	T	C	11: 46,098,263 (GRCm39)	Y1053C	probably damaging	Het
Diaph1	A	G	18: 38,024,988 (GRCm39)	V491A	unknown	Het
Dync2i1	A	T	12: 116,197,014 (GRCm39)	F448I	possibly damaging	Het
Ehf	T	C	2: 103,097,338 (GRCm39)		probably null	Het
Eif2b5	C	T	16: 20,326,874 (GRCm39)	H99Y	probably benign	Het
Exosc10	C	A	4: 148,657,819 (GRCm39)	T655K	probably benign	Het
Flg	A	T	3: 93,186,706 (GRCm39)	I53F	probably damaging	Het
Hc	T	A	2: 34,920,462 (GRCm39)	D628V	possibly damaging	Het
Lmo4	A	T	3: 143,900,252 (GRCm39)	N83K	probably benign	Het
Lrp4	A	T	2: 91,342,029 (GRCm39)	T1881S	probably benign	Het
Malt1	T	A	18: 65,564,439 (GRCm39)	L66Q	possibly damaging	Het
Map3k3	T	C	11: 106,040,376 (GRCm39)	S314P	probably benign	Het
Mpzl3	G	T	9: 44,973,412 (GRCm39)	K50N	probably damaging	Het
Nbeal2	G	T	9: 110,458,948 (GRCm39)	Q1992K	probably benign	Het
Nlrp14	T	A	7: 106,785,860 (GRCm39)	N645K	probably benign	Het
Or2g1	T	C	17: 38,106,482 (GRCm39)	I49T	probably benign	Het
Or6c76b	A	G	10: 129,692,744 (GRCm39)	D119G	probably damaging	Het
Pcdha1	T	A	18: 37,063,724 (GRCm39)	D129E	probably damaging	Het
Prb1a	A	G	6: 132,187,475 (GRCm39)	L2P	unknown	Het
Rhbdf1	A	G	11: 32,162,906 (GRCm39)	Y454H	probably benign	Het
Satb2	C	T	1: 56,836,097 (GRCm39)	A565T	possibly damaging	Het
Sh3pxd2a	A	T	19: 47,256,051 (GRCm39)	L889Q	probably damaging	Het
Sis	T	C	3: 72,828,713 (GRCm39)		probably null	Het
Slc35e2	T	C	4: 155,696,084 (GRCm39)	V157A	probably damaging	Het
Slc35f3	T	C	8: 127,115,946 (GRCm39)	V291A	probably benign	Het
Snph	T	C	2: 151,436,151 (GRCm39)	D190G	probably damaging	Het
Tpd52l1	T	C	10: 31,208,943 (GRCm39)	H170R	probably benign	Het
Trav18	A	G	14: 54,069,152 (GRCm39)	T65A	probably benign	Het
Trip12	G	A	1: 84,726,974 (GRCm39)	Q9*	probably null	Het
Ttn	C	T	2: 76,632,592 (GRCm39)	C12408Y	probably damaging	Het
Ttn	T	C	2: 76,639,355 (GRCm39)	D13806G	probably damaging	Het
Vmn2r81	T	C	10: 79,083,637 (GRCm39)	S4P	probably damaging	Het
Zfp37	G	A	4: 62,109,450 (GRCm39)	T576I	possibly damaging	Het
Zfp39	A	T	11: 58,782,099 (GRCm39)	L221Q	possibly damaging	Het
Zgrf1	A	G	3: 127,366,853 (GRCm39)	H744R	possibly damaging	Het

Other mutations in Unc79

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00718:Unc79	APN	12	103,135,906 (GRCm39)	missense	possibly damaging	0.68
IGL00835:Unc79	APN	12	103,108,149 (GRCm39)	splice site	probably benign
IGL00917:Unc79	APN	12	103,054,766 (GRCm39)	missense	possibly damaging	0.53
IGL01012:Unc79	APN	12	103,078,714 (GRCm39)	missense	probably damaging	1.00
IGL01121:Unc79	APN	12	103,131,890 (GRCm39)	missense	probably damaging	0.99
IGL01303:Unc79	APN	12	103,128,126 (GRCm39)	missense	possibly damaging	0.94
IGL01305:Unc79	APN	12	102,968,130 (GRCm39)	missense	probably damaging	0.99
IGL01315:Unc79	APN	12	103,054,780 (GRCm39)	missense	possibly damaging	0.66
IGL01388:Unc79	APN	12	103,136,018 (GRCm39)	splice site	probably benign
IGL01415:Unc79	APN	12	103,074,944 (GRCm39)	missense	probably damaging	1.00
IGL01447:Unc79	APN	12	103,045,177 (GRCm39)	missense	probably damaging	1.00
IGL01655:Unc79	APN	12	103,134,546 (GRCm39)	missense	probably benign	0.00
IGL01662:Unc79	APN	12	103,115,279 (GRCm39)	missense	possibly damaging	0.92
IGL01728:Unc79	APN	12	103,131,943 (GRCm39)	missense	probably damaging	0.98
IGL01767:Unc79	APN	12	103,108,256 (GRCm39)	missense	probably damaging	1.00
IGL02080:Unc79	APN	12	102,968,234 (GRCm39)	missense	probably damaging	1.00
IGL02115:Unc79	APN	12	102,964,933 (GRCm39)	missense	probably damaging	1.00
IGL02176:Unc79	APN	12	102,965,006 (GRCm39)	splice site	probably null
IGL02186:Unc79	APN	12	102,977,542 (GRCm39)	missense	probably benign	0.04
IGL02205:Unc79	APN	12	103,045,260 (GRCm39)	missense	probably damaging	1.00
IGL02337:Unc79	APN	12	103,122,705 (GRCm39)	splice site	probably benign
IGL02498:Unc79	APN	12	103,137,837 (GRCm39)	missense	probably damaging	0.99
IGL02508:Unc79	APN	12	103,078,535 (GRCm39)	missense	probably damaging	0.97
IGL02508:Unc79	APN	12	103,078,277 (GRCm39)	splice site	probably benign
IGL02557:Unc79	APN	12	103,148,418 (GRCm39)	splice site	probably benign
IGL02589:Unc79	APN	12	103,139,755 (GRCm39)	missense	probably damaging	1.00
IGL02611:Unc79	APN	12	103,131,967 (GRCm39)	missense	probably damaging	0.97
IGL02728:Unc79	APN	12	103,088,688 (GRCm39)	missense	possibly damaging	0.53
IGL02827:Unc79	APN	12	103,041,105 (GRCm39)	missense	possibly damaging	0.88
IGL03028:Unc79	APN	12	103,139,785 (GRCm39)	missense	possibly damaging	0.83
IGL03144:Unc79	APN	12	103,008,401 (GRCm39)	missense	probably damaging	1.00
IGL03229:Unc79	APN	12	103,100,798 (GRCm39)	missense	probably damaging	0.99
IGL03269:Unc79	APN	12	103,054,936 (GRCm39)	missense	probably damaging	1.00
IGL03325:Unc79	APN	12	103,135,869 (GRCm39)	missense	probably damaging	0.98
pencil-thin	UTSW	12	103,075,040 (GRCm39)	splice site	probably null
sweetpea	UTSW	12	103,025,777 (GRCm39)	missense	probably damaging	1.00
3-1:Unc79	UTSW	12	103,039,009 (GRCm39)	nonsense	probably null
ANU22:Unc79	UTSW	12	102,968,130 (GRCm39)	missense	probably damaging	0.99
R0046:Unc79	UTSW	12	103,091,940 (GRCm39)	missense	probably damaging	0.99
R0046:Unc79	UTSW	12	103,091,940 (GRCm39)	missense	probably damaging	0.99
R0067:Unc79	UTSW	12	103,025,777 (GRCm39)	missense	probably damaging	1.00
R0067:Unc79	UTSW	12	103,025,777 (GRCm39)	missense	probably damaging	1.00
R0107:Unc79	UTSW	12	103,100,784 (GRCm39)	missense	possibly damaging	0.70
R0110:Unc79	UTSW	12	103,045,329 (GRCm39)	critical splice donor site	probably null
R0128:Unc79	UTSW	12	103,054,693 (GRCm39)	splice site	probably benign
R0166:Unc79	UTSW	12	103,122,812 (GRCm39)	missense	probably damaging	1.00
R0208:Unc79	UTSW	12	103,058,286 (GRCm39)	missense	probably benign	0.00
R0211:Unc79	UTSW	12	103,039,051 (GRCm39)	missense	probably benign	0.01
R0211:Unc79	UTSW	12	103,039,051 (GRCm39)	missense	probably benign	0.01
R0218:Unc79	UTSW	12	103,075,040 (GRCm39)	splice site	probably null
R0244:Unc79	UTSW	12	103,079,150 (GRCm39)	missense	probably damaging	1.00
R0305:Unc79	UTSW	12	103,079,459 (GRCm39)	missense	probably benign	0.18
R0310:Unc79	UTSW	12	103,027,666 (GRCm39)	missense	probably damaging	1.00
R0325:Unc79	UTSW	12	103,137,903 (GRCm39)	missense	probably damaging	0.98
R0369:Unc79	UTSW	12	103,055,031 (GRCm39)	critical splice donor site	probably null
R0450:Unc79	UTSW	12	103,045,329 (GRCm39)	critical splice donor site	probably null
R0503:Unc79	UTSW	12	103,045,127 (GRCm39)	missense	probably benign	0.01
R0542:Unc79	UTSW	12	103,060,437 (GRCm39)	splice site	probably benign
R0845:Unc79	UTSW	12	103,139,703 (GRCm39)	splice site	probably benign
R0893:Unc79	UTSW	12	102,957,687 (GRCm39)	missense	probably damaging	1.00
R1078:Unc79	UTSW	12	103,041,112 (GRCm39)	missense	probably benign	0.03
R1148:Unc79	UTSW	12	103,078,926 (GRCm39)	missense	probably damaging	1.00
R1148:Unc79	UTSW	12	103,078,926 (GRCm39)	missense	probably damaging	1.00
R1159:Unc79	UTSW	12	103,013,311 (GRCm39)	splice site	probably benign
R1191:Unc79	UTSW	12	103,013,271 (GRCm39)	nonsense	probably null
R1307:Unc79	UTSW	12	103,036,335 (GRCm39)	missense	probably damaging	1.00
R1368:Unc79	UTSW	12	103,122,772 (GRCm39)	missense	probably damaging	1.00
R1476:Unc79	UTSW	12	103,149,784 (GRCm39)	missense	probably damaging	1.00
R1650:Unc79	UTSW	12	103,079,052 (GRCm39)	missense	possibly damaging	0.85
R1777:Unc79	UTSW	12	103,078,714 (GRCm39)	missense	probably damaging	1.00
R1796:Unc79	UTSW	12	103,109,005 (GRCm39)	missense	probably damaging	0.99
R1824:Unc79	UTSW	12	103,025,579 (GRCm39)	missense	probably damaging	1.00
R1830:Unc79	UTSW	12	103,100,737 (GRCm39)	missense	probably damaging	1.00
R1927:Unc79	UTSW	12	103,135,951 (GRCm39)	missense	probably damaging	1.00
R1958:Unc79	UTSW	12	103,041,178 (GRCm39)	missense	probably benign	0.19
R1958:Unc79	UTSW	12	102,957,621 (GRCm39)	missense	probably damaging	1.00
R1980:Unc79	UTSW	12	102,977,538 (GRCm39)	nonsense	probably null
R2019:Unc79	UTSW	12	103,137,830 (GRCm39)	critical splice acceptor site	probably null
R2290:Unc79	UTSW	12	103,112,625 (GRCm39)	missense	probably damaging	1.00
R2939:Unc79	UTSW	12	102,957,684 (GRCm39)	missense	probably damaging	1.00
R2962:Unc79	UTSW	12	103,061,378 (GRCm39)	missense	possibly damaging	0.72
R3176:Unc79	UTSW	12	103,079,476 (GRCm39)	missense	probably damaging	1.00
R3276:Unc79	UTSW	12	103,079,476 (GRCm39)	missense	probably damaging	1.00
R3683:Unc79	UTSW	12	103,041,062 (GRCm39)	missense	probably benign	0.00
R3684:Unc79	UTSW	12	103,041,062 (GRCm39)	missense	probably benign	0.00
R3686:Unc79	UTSW	12	103,054,920 (GRCm39)	missense	probably damaging	1.00
R3760:Unc79	UTSW	12	103,058,964 (GRCm39)	missense	probably damaging	1.00
R4031:Unc79	UTSW	12	103,039,018 (GRCm39)	missense	possibly damaging	0.46
R4039:Unc79	UTSW	12	103,041,208 (GRCm39)	missense	possibly damaging	0.88
R4110:Unc79	UTSW	12	103,025,629 (GRCm39)	missense	probably damaging	1.00
R4113:Unc79	UTSW	12	103,025,629 (GRCm39)	missense	probably damaging	1.00
R4159:Unc79	UTSW	12	103,036,512 (GRCm39)	intron	probably benign
R4273:Unc79	UTSW	12	103,088,612 (GRCm39)	missense	probably damaging	0.99
R4292:Unc79	UTSW	12	103,149,703 (GRCm39)	missense	probably damaging	0.99
R4334:Unc79	UTSW	12	103,045,233 (GRCm39)	missense	probably benign
R4513:Unc79	UTSW	12	102,988,019 (GRCm39)	missense	probably damaging	1.00
R4562:Unc79	UTSW	12	102,957,720 (GRCm39)	missense	probably damaging	1.00
R4576:Unc79	UTSW	12	102,968,062 (GRCm39)	splice site	probably benign
R4645:Unc79	UTSW	12	103,079,081 (GRCm39)	missense	probably benign
R4758:Unc79	UTSW	12	103,128,080 (GRCm39)	nonsense	probably null
R4787:Unc79	UTSW	12	103,013,257 (GRCm39)	missense	probably damaging	1.00
R4852:Unc79	UTSW	12	103,139,725 (GRCm39)	missense	probably damaging	0.98
R4883:Unc79	UTSW	12	103,060,592 (GRCm39)	missense	probably damaging	0.99
R4898:Unc79	UTSW	12	103,128,079 (GRCm39)	missense	probably damaging	0.99
R4979:Unc79	UTSW	12	103,078,691 (GRCm39)	missense	probably benign
R5044:Unc79	UTSW	12	103,078,962 (GRCm39)	missense	probably benign	0.32
R5053:Unc79	UTSW	12	103,071,007 (GRCm39)	missense	probably damaging	1.00
R5061:Unc79	UTSW	12	103,134,700 (GRCm39)	missense	possibly damaging	0.94
R5075:Unc79	UTSW	12	103,041,213 (GRCm39)	missense	possibly damaging	0.63
R5101:Unc79	UTSW	12	103,078,769 (GRCm39)	missense	probably damaging	1.00
R5236:Unc79	UTSW	12	103,060,654 (GRCm39)	critical splice donor site	probably null
R5240:Unc79	UTSW	12	103,037,010 (GRCm39)	missense	probably damaging	0.99
R5383:Unc79	UTSW	12	103,070,886 (GRCm39)	missense	possibly damaging	0.53
R5461:Unc79	UTSW	12	103,078,397 (GRCm39)	missense	probably damaging	1.00
R5535:Unc79	UTSW	12	103,135,962 (GRCm39)	missense	possibly damaging	0.84
R5609:Unc79	UTSW	12	103,094,527 (GRCm39)	missense	probably benign
R5639:Unc79	UTSW	12	103,137,831 (GRCm39)	missense	probably damaging	1.00
R5704:Unc79	UTSW	12	102,968,202 (GRCm39)	missense	probably damaging	1.00
R5923:Unc79	UTSW	12	103,078,727 (GRCm39)	missense	probably damaging	1.00
R5975:Unc79	UTSW	12	103,091,885 (GRCm39)	missense	possibly damaging	0.53
R6047:Unc79	UTSW	12	103,027,717 (GRCm39)	missense	probably damaging	1.00
R6156:Unc79	UTSW	12	103,027,717 (GRCm39)	missense	probably damaging	1.00
R6175:Unc79	UTSW	12	103,149,708 (GRCm39)	missense	probably damaging	0.98
R6292:Unc79	UTSW	12	103,108,991 (GRCm39)	missense	possibly damaging	0.88
R6313:Unc79	UTSW	12	103,078,878 (GRCm39)	missense	probably damaging	1.00
R6391:Unc79	UTSW	12	102,987,269 (GRCm39)	missense	probably damaging	1.00
R6405:Unc79	UTSW	12	103,134,595 (GRCm39)	missense	probably damaging	0.97
R6416:Unc79	UTSW	12	103,097,905 (GRCm39)	missense	possibly damaging	0.86
R6467:Unc79	UTSW	12	103,139,771 (GRCm39)	missense	probably damaging	1.00
R6573:Unc79	UTSW	12	103,027,647 (GRCm39)	missense	probably damaging	1.00
R6614:Unc79	UTSW	12	102,957,689 (GRCm39)	missense	probably damaging	1.00
R6654:Unc79	UTSW	12	103,045,308 (GRCm39)	missense	probably damaging	1.00
R6654:Unc79	UTSW	12	103,045,307 (GRCm39)	missense	probably damaging	0.99
R6700:Unc79	UTSW	12	103,091,962 (GRCm39)	missense	possibly damaging	0.92
R6724:Unc79	UTSW	12	103,071,120 (GRCm39)	missense	probably damaging	1.00
R6819:Unc79	UTSW	12	103,108,267 (GRCm39)	missense	probably benign	0.12
R6869:Unc79	UTSW	12	103,079,331 (GRCm39)	missense	probably benign	0.33
R6879:Unc79	UTSW	12	103,115,046 (GRCm39)	splice site	probably null
R6942:Unc79	UTSW	12	103,088,704 (GRCm39)	critical splice donor site	probably null
R6961:Unc79	UTSW	12	103,079,174 (GRCm39)	missense	probably damaging	1.00
R6973:Unc79	UTSW	12	102,964,699 (GRCm39)	missense	possibly damaging	0.86
R6980:Unc79	UTSW	12	103,025,759 (GRCm39)	missense	probably damaging	1.00
R7124:Unc79	UTSW	12	103,027,652 (GRCm39)	missense	probably damaging	0.99
R7144:Unc79	UTSW	12	103,108,885 (GRCm39)	missense	probably benign	0.06
R7197:Unc79	UTSW	12	103,078,765 (GRCm39)	missense	probably benign
R7209:Unc79	UTSW	12	103,091,883 (GRCm39)	missense	probably benign
R7232:Unc79	UTSW	12	103,100,734 (GRCm39)	missense	possibly damaging	0.49
R7304:Unc79	UTSW	12	103,029,449 (GRCm39)	missense	probably damaging	1.00
R7354:Unc79	UTSW	12	103,108,961 (GRCm39)	missense	possibly damaging	0.79
R7384:Unc79	UTSW	12	103,137,837 (GRCm39)	missense	probably benign	0.11
R7400:Unc79	UTSW	12	103,070,889 (GRCm39)	missense	probably damaging	1.00
R7417:Unc79	UTSW	12	103,055,017 (GRCm39)	missense	possibly damaging	0.85
R7470:Unc79	UTSW	12	103,061,235 (GRCm39)	missense	probably damaging	1.00
R7842:Unc79	UTSW	12	103,058,313 (GRCm39)	missense	probably damaging	1.00
R8037:Unc79	UTSW	12	103,016,178 (GRCm39)	missense	probably damaging	1.00
R8041:Unc79	UTSW	12	103,054,726 (GRCm39)	missense	probably benign	0.06
R8146:Unc79	UTSW	12	103,036,416 (GRCm39)	missense	probably damaging	0.98
R8276:Unc79	UTSW	12	102,968,122 (GRCm39)	missense	possibly damaging	0.94
R8427:Unc79	UTSW	12	103,045,297 (GRCm39)	missense	probably benign	0.24
R8501:Unc79	UTSW	12	103,058,897 (GRCm39)	missense	probably damaging	1.00
R8510:Unc79	UTSW	12	103,070,898 (GRCm39)	missense	probably damaging	1.00
R8531:Unc79	UTSW	12	103,013,922 (GRCm39)	missense	probably damaging	1.00
R8531:Unc79	UTSW	12	103,049,855 (GRCm39)	missense	probably benign	0.13
R8795:Unc79	UTSW	12	103,074,513 (GRCm39)	missense	probably damaging	1.00
R9017:Unc79	UTSW	12	103,074,874 (GRCm39)	critical splice acceptor site	probably null
R9121:Unc79	UTSW	12	102,968,095 (GRCm39)	missense	probably damaging	1.00
R9196:Unc79	UTSW	12	103,078,613 (GRCm39)	missense	probably benign
R9443:Unc79	UTSW	12	103,037,035 (GRCm39)	missense	probably damaging	1.00
R9548:Unc79	UTSW	12	102,977,495 (GRCm39)	missense	probably damaging	1.00
R9600:Unc79	UTSW	12	103,135,972 (GRCm39)	missense	probably benign	0.07
R9767:Unc79	UTSW	12	103,079,234 (GRCm39)	missense	probably benign
R9787:Unc79	UTSW	12	103,112,620 (GRCm39)	missense	probably benign	0.00
RF010:Unc79	UTSW	12	103,079,046 (GRCm39)	missense	probably benign	0.17
X0017:Unc79	UTSW	12	103,074,520 (GRCm39)	missense	probably damaging	0.99
X0028:Unc79	UTSW	12	102,957,662 (GRCm39)	missense	probably damaging	1.00
Z1088:Unc79	UTSW	12	102,987,271 (GRCm39)	missense	probably damaging	1.00
Z1176:Unc79	UTSW	12	103,108,312 (GRCm39)	missense	probably benign	0.03
Z1176:Unc79	UTSW	12	103,054,937 (GRCm39)	missense	probably damaging	1.00
Z1177:Unc79	UTSW	12	103,131,948 (GRCm39)	missense	probably benign

Predicted Primers

PCR Primer
(F):5'- GATGTGTAGAGCCTTGTCCG -3'
(R):5'- TAGACAGGAACCAGCCTAGGTG -3'

Sequencing Primer
(F):5'- GTAGAGCCTTGTCCGTAGTAACC -3'
(R):5'- TTTAACCAAAGAACACAAAAAGTGG -3'

Posted On

2017-02-28