Incidental Mutation 'R8963:Aatk'
| ID |
682508 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Aatk
|
| Ensembl Gene |
ENSMUSG00000025375 |
| Gene Name |
apoptosis-associated tyrosine kinase |
| Synonyms |
AATYK1 |
| MMRRC Submission |
068797-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.135)
|
| Stock # |
R8963 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
11 |
| Chromosomal Location |
119898139-119937993 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 119902963 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Alanine
at position 421
(T421A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000099309
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000064307]
[ENSMUST00000103019]
[ENSMUST00000103020]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000064307
AA Change: T478A
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000067181
Gene: ENSMUSG00000025375
AA Change: T478A
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
low complexity region
|
30 |
49 |
N/A |
INTRINSIC |
|
Pfam:Pkinase_Tyr
|
135 |
405 |
3.9e-63 |
PFAM |
|
Pfam:Pkinase
|
136 |
404 |
2.6e-33 |
PFAM |
|
low complexity region
|
425 |
457 |
N/A |
INTRINSIC |
|
low complexity region
|
502 |
514 |
N/A |
INTRINSIC |
|
low complexity region
|
615 |
624 |
N/A |
INTRINSIC |
|
low complexity region
|
647 |
666 |
N/A |
INTRINSIC |
|
low complexity region
|
684 |
695 |
N/A |
INTRINSIC |
|
low complexity region
|
808 |
819 |
N/A |
INTRINSIC |
|
low complexity region
|
913 |
927 |
N/A |
INTRINSIC |
|
low complexity region
|
934 |
943 |
N/A |
INTRINSIC |
|
low complexity region
|
985 |
1004 |
N/A |
INTRINSIC |
|
low complexity region
|
1063 |
1082 |
N/A |
INTRINSIC |
|
low complexity region
|
1085 |
1096 |
N/A |
INTRINSIC |
|
low complexity region
|
1160 |
1174 |
N/A |
INTRINSIC |
|
low complexity region
|
1179 |
1204 |
N/A |
INTRINSIC |
|
low complexity region
|
1319 |
1333 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000103019
AA Change: T421A
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000099308
Gene: ENSMUSG00000025375
AA Change: T421A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Pkinase
|
78 |
347 |
3e-36 |
PFAM |
|
Pfam:Pkinase_Tyr
|
78 |
348 |
1.9e-62 |
PFAM |
|
low complexity region
|
368 |
400 |
N/A |
INTRINSIC |
|
low complexity region
|
445 |
457 |
N/A |
INTRINSIC |
|
low complexity region
|
558 |
567 |
N/A |
INTRINSIC |
|
low complexity region
|
590 |
609 |
N/A |
INTRINSIC |
|
low complexity region
|
627 |
638 |
N/A |
INTRINSIC |
|
low complexity region
|
751 |
762 |
N/A |
INTRINSIC |
|
low complexity region
|
856 |
870 |
N/A |
INTRINSIC |
|
low complexity region
|
877 |
886 |
N/A |
INTRINSIC |
|
low complexity region
|
928 |
947 |
N/A |
INTRINSIC |
|
low complexity region
|
1006 |
1025 |
N/A |
INTRINSIC |
|
low complexity region
|
1028 |
1039 |
N/A |
INTRINSIC |
|
low complexity region
|
1103 |
1117 |
N/A |
INTRINSIC |
|
low complexity region
|
1122 |
1147 |
N/A |
INTRINSIC |
|
low complexity region
|
1262 |
1276 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000103020
AA Change: T421A
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000099309
Gene: ENSMUSG00000025375
AA Change: T421A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Pkinase
|
78 |
347 |
3e-36 |
PFAM |
|
Pfam:Pkinase_Tyr
|
78 |
348 |
1.9e-62 |
PFAM |
|
low complexity region
|
368 |
400 |
N/A |
INTRINSIC |
|
low complexity region
|
445 |
457 |
N/A |
INTRINSIC |
|
low complexity region
|
558 |
567 |
N/A |
INTRINSIC |
|
low complexity region
|
590 |
609 |
N/A |
INTRINSIC |
|
low complexity region
|
627 |
638 |
N/A |
INTRINSIC |
|
low complexity region
|
751 |
762 |
N/A |
INTRINSIC |
|
low complexity region
|
856 |
870 |
N/A |
INTRINSIC |
|
low complexity region
|
877 |
886 |
N/A |
INTRINSIC |
|
low complexity region
|
928 |
947 |
N/A |
INTRINSIC |
|
low complexity region
|
1006 |
1025 |
N/A |
INTRINSIC |
|
low complexity region
|
1028 |
1039 |
N/A |
INTRINSIC |
|
low complexity region
|
1103 |
1117 |
N/A |
INTRINSIC |
|
low complexity region
|
1122 |
1147 |
N/A |
INTRINSIC |
|
low complexity region
|
1262 |
1276 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.5%
- 20x: 98.4%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased brain size, longer axons and fewer neurites. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 78 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adamts12 |
T |
C |
15: 11,317,443 (GRCm39) |
|
probably null |
Het |
| Adgrv1 |
A |
T |
13: 81,567,588 (GRCm39) |
V5195E |
probably benign |
Het |
| Adora2b |
C |
T |
11: 62,139,983 (GRCm39) |
A19V |
possibly damaging |
Het |
| Ankrd28 |
A |
G |
14: 31,477,698 (GRCm39) |
C115R |
probably benign |
Het |
| Ankrd35 |
T |
A |
3: 96,587,003 (GRCm39) |
L106* |
probably null |
Het |
| Ankrd44 |
G |
A |
1: 54,801,538 (GRCm39) |
A263V |
probably damaging |
Het |
| Apol7b |
T |
C |
15: 77,308,120 (GRCm39) |
K125R |
possibly damaging |
Het |
| Cacna1c |
A |
T |
6: 118,719,232 (GRCm39) |
L245* |
probably null |
Het |
| Cbll1 |
A |
T |
12: 31,538,199 (GRCm39) |
H185Q |
probably damaging |
Het |
| Ccdc150 |
A |
C |
1: 54,311,641 (GRCm39) |
N209T |
probably benign |
Het |
| Ccdc88a |
T |
A |
11: 29,448,416 (GRCm39) |
N1465K |
possibly damaging |
Het |
| Cfap54 |
C |
A |
10: 92,864,562 (GRCm39) |
G124* |
probably null |
Het |
| Chml |
A |
T |
1: 175,514,601 (GRCm39) |
L440H |
probably damaging |
Het |
| Chrnd |
A |
T |
1: 87,122,603 (GRCm39) |
Q128L |
probably damaging |
Het |
| Clvs2 |
A |
T |
10: 33,498,677 (GRCm39) |
D84E |
probably benign |
Het |
| Ctif |
CGGGGCACACTTTGCTCTTACCTCCCGGAGGCACGTGTAGATGGGGCACACTTTGCTCTTACCTCCCGGAGGCACGTGTAGATGGGGCACAC |
CGGGGCACACTTTGCTCTTACCTCCCGGAGGCACGTGTAGATGGGGCACAC |
18: 75,604,874 (GRCm39) |
|
probably benign |
Het |
| Cyp2c40 |
T |
A |
19: 39,755,926 (GRCm39) |
I463F |
possibly damaging |
Het |
| Cyp51 |
C |
A |
5: 4,136,519 (GRCm39) |
R425L |
probably damaging |
Het |
| Daam1 |
A |
G |
12: 71,992,018 (GRCm39) |
T279A |
unknown |
Het |
| Ebf2 |
G |
T |
14: 67,665,554 (GRCm39) |
V571F |
probably benign |
Het |
| Elapor2 |
T |
A |
5: 9,487,792 (GRCm39) |
N559K |
probably damaging |
Het |
| Elavl4 |
A |
T |
4: 110,063,776 (GRCm39) |
I275N |
probably damaging |
Het |
| F11r |
A |
G |
1: 171,288,505 (GRCm39) |
Q116R |
probably benign |
Het |
| Foxred2 |
T |
A |
15: 77,829,805 (GRCm39) |
D580V |
probably benign |
Het |
| Gatad1 |
A |
C |
5: 3,691,544 (GRCm39) |
L4R |
probably damaging |
Het |
| Gcn1 |
T |
A |
5: 115,727,153 (GRCm39) |
M670K |
probably benign |
Het |
| Greb1 |
A |
T |
12: 16,774,885 (GRCm39) |
F171I |
probably damaging |
Het |
| Grin2b |
A |
G |
6: 136,021,007 (GRCm39) |
V98A |
probably damaging |
Het |
| Helz2 |
A |
T |
2: 180,871,407 (GRCm39) |
V2735E |
probably damaging |
Het |
| Hrct1 |
A |
T |
4: 43,727,564 (GRCm39) |
|
probably benign |
Het |
| Ighv1-11 |
C |
T |
12: 114,575,864 (GRCm39) |
R117K |
probably damaging |
Het |
| Igkv12-46 |
A |
T |
6: 69,741,754 (GRCm39) |
S34T |
probably damaging |
Het |
| Il27ra |
T |
A |
8: 84,767,711 (GRCm39) |
N71Y |
probably damaging |
Het |
| Iqca1 |
G |
T |
1: 90,067,649 (GRCm39) |
H201N |
probably benign |
Het |
| Itgb1bp1 |
C |
T |
12: 21,324,864 (GRCm39) |
R64Q |
probably damaging |
Het |
| Katnb1 |
T |
C |
8: 95,809,519 (GRCm39) |
L13S |
probably damaging |
Het |
| Kif26b |
G |
A |
1: 178,743,714 (GRCm39) |
R1270Q |
probably benign |
Het |
| Klhdc2 |
A |
T |
12: 69,347,065 (GRCm39) |
R77* |
probably null |
Het |
| Klra10 |
A |
T |
6: 130,249,617 (GRCm39) |
|
probably null |
Het |
| Large1 |
A |
T |
8: 73,542,612 (GRCm39) |
I704N |
probably damaging |
Het |
| Lrp1b |
G |
A |
2: 40,888,196 (GRCm39) |
H2241Y |
probably benign |
Het |
| Lrpap1 |
T |
A |
5: 35,255,001 (GRCm39) |
M212L |
probably benign |
Het |
| Mab21l1 |
A |
G |
3: 55,690,348 (GRCm39) |
|
probably benign |
Het |
| Map4k4 |
A |
T |
1: 40,039,740 (GRCm39) |
Q44L |
probably damaging |
Het |
| Map7d1 |
A |
G |
4: 126,130,475 (GRCm39) |
S412P |
probably damaging |
Het |
| Me1 |
A |
T |
9: 86,480,844 (GRCm39) |
F354I |
probably damaging |
Het |
| Nlrp1b |
A |
G |
11: 71,108,658 (GRCm39) |
V281A |
probably damaging |
Het |
| Nrip2 |
A |
G |
6: 128,385,288 (GRCm39) |
T240A |
possibly damaging |
Het |
| Nsmaf |
A |
G |
4: 6,428,471 (GRCm39) |
V203A |
probably damaging |
Het |
| Or12e8 |
T |
A |
2: 87,187,950 (GRCm39) |
I54K |
possibly damaging |
Het |
| Or4g17 |
A |
T |
2: 111,209,645 (GRCm39) |
Q100L |
probably damaging |
Het |
| Or4n5 |
A |
T |
14: 50,132,509 (GRCm39) |
M250K |
probably benign |
Het |
| Or8g2 |
A |
G |
9: 39,821,495 (GRCm39) |
Y132C |
probably damaging |
Het |
| P4ha2 |
T |
C |
11: 54,004,995 (GRCm39) |
F124L |
probably benign |
Het |
| Pcdha9 |
A |
T |
18: 37,131,750 (GRCm39) |
D273V |
probably benign |
Het |
| Pkd1l3 |
GACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCA |
GACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCAACAAACATGACATCAGACACACCTGCATCCAGCAGCCCA |
8: 110,350,827 (GRCm39) |
|
probably benign |
Het |
| Plxnd1 |
G |
T |
6: 115,949,506 (GRCm39) |
S760* |
probably null |
Het |
| Polr1b |
A |
G |
2: 128,957,576 (GRCm39) |
T544A |
probably benign |
Het |
| Polr2g |
T |
C |
19: 8,771,513 (GRCm39) |
D153G |
probably damaging |
Het |
| Pramel12 |
T |
C |
4: 143,144,229 (GRCm39) |
Y192H |
probably benign |
Het |
| Rad51ap2 |
A |
C |
12: 11,506,255 (GRCm39) |
E59A |
possibly damaging |
Het |
| Rrm1 |
A |
T |
7: 102,105,739 (GRCm39) |
Y285F |
probably benign |
Het |
| Ryr3 |
A |
G |
2: 112,667,015 (GRCm39) |
|
probably null |
Het |
| Scaf4 |
GGCTGCTGCTGCTGCTGCTGCTGCTG |
GGCTGCTGCTGCTGCTGCTGCTG |
16: 90,026,745 (GRCm39) |
|
probably benign |
Het |
| Sftpd |
A |
G |
14: 40,905,001 (GRCm39) |
V30A |
probably benign |
Het |
| Sirt6 |
A |
G |
10: 81,462,378 (GRCm39) |
V7A |
probably benign |
Het |
| Ska1 |
C |
T |
18: 74,330,639 (GRCm39) |
V188M |
probably damaging |
Het |
| Skint8 |
G |
A |
4: 111,794,241 (GRCm39) |
M210I |
probably benign |
Het |
| Slc6a11 |
A |
G |
6: 114,202,782 (GRCm39) |
|
probably null |
Het |
| Slc6a2 |
A |
T |
8: 93,715,702 (GRCm39) |
H280L |
probably benign |
Het |
| Sptan1 |
T |
C |
2: 29,873,744 (GRCm39) |
V208A |
possibly damaging |
Het |
| Taf6l |
T |
A |
19: 8,752,135 (GRCm39) |
T518S |
probably benign |
Het |
| Thoc2l |
T |
C |
5: 104,665,652 (GRCm39) |
V58A |
probably benign |
Het |
| Tsc22d1 |
T |
C |
14: 76,656,266 (GRCm39) |
M59T |
probably benign |
Het |
| Unc5cl |
A |
G |
17: 48,769,361 (GRCm39) |
T282A |
probably benign |
Het |
| Vav3 |
A |
G |
3: 109,590,229 (GRCm39) |
K260E |
probably damaging |
Het |
| Vmn2r53 |
A |
G |
7: 12,315,926 (GRCm39) |
V631A |
probably damaging |
Het |
| Zfp938 |
A |
T |
10: 82,061,287 (GRCm39) |
F444L |
possibly damaging |
Het |
|
| Other mutations in Aatk |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00497:Aatk
|
APN |
11 |
119,901,012 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL00953:Aatk
|
APN |
11 |
119,902,047 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01019:Aatk
|
APN |
11 |
119,903,101 (GRCm39) |
missense |
probably benign |
|
|
IGL01758:Aatk
|
APN |
11 |
119,901,645 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
IGL02377:Aatk
|
APN |
11 |
119,937,689 (GRCm39) |
utr 5 prime |
probably benign |
|
|
IGL02902:Aatk
|
APN |
11 |
119,902,603 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03067:Aatk
|
APN |
11 |
119,900,909 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03116:Aatk
|
APN |
11 |
119,907,577 (GRCm39) |
missense |
probably benign |
0.14 |
|
IGL03279:Aatk
|
APN |
11 |
119,904,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03405:Aatk
|
APN |
11 |
119,907,229 (GRCm39) |
missense |
probably benign |
0.02 |
|
PIT4366001:Aatk
|
UTSW |
11 |
119,901,786 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
PIT4802001:Aatk
|
UTSW |
11 |
119,902,172 (GRCm39) |
missense |
probably benign |
|
|
R0101:Aatk
|
UTSW |
11 |
119,901,739 (GRCm39) |
missense |
probably benign |
0.19 |
|
R0497:Aatk
|
UTSW |
11 |
119,909,606 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0535:Aatk
|
UTSW |
11 |
119,901,019 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0638:Aatk
|
UTSW |
11 |
119,900,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0939:Aatk
|
UTSW |
11 |
119,902,969 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1475:Aatk
|
UTSW |
11 |
119,901,714 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1840:Aatk
|
UTSW |
11 |
119,904,558 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1865:Aatk
|
UTSW |
11 |
119,901,048 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1982:Aatk
|
UTSW |
11 |
119,904,340 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2027:Aatk
|
UTSW |
11 |
119,900,143 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2115:Aatk
|
UTSW |
11 |
119,900,562 (GRCm39) |
missense |
probably benign |
|
|
R2220:Aatk
|
UTSW |
11 |
119,903,003 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2264:Aatk
|
UTSW |
11 |
119,901,100 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2504:Aatk
|
UTSW |
11 |
119,909,681 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3872:Aatk
|
UTSW |
11 |
119,901,045 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R4551:Aatk
|
UTSW |
11 |
119,902,395 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4657:Aatk
|
UTSW |
11 |
119,904,304 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R4744:Aatk
|
UTSW |
11 |
119,906,948 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R4924:Aatk
|
UTSW |
11 |
119,902,351 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5063:Aatk
|
UTSW |
11 |
119,901,315 (GRCm39) |
missense |
probably benign |
0.07 |
|
R5223:Aatk
|
UTSW |
11 |
119,904,278 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5243:Aatk
|
UTSW |
11 |
119,907,594 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5376:Aatk
|
UTSW |
11 |
119,902,860 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5442:Aatk
|
UTSW |
11 |
119,909,594 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5550:Aatk
|
UTSW |
11 |
119,900,129 (GRCm39) |
missense |
probably benign |
0.42 |
|
R5678:Aatk
|
UTSW |
11 |
119,900,980 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5932:Aatk
|
UTSW |
11 |
119,912,359 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6026:Aatk
|
UTSW |
11 |
119,903,190 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R6129:Aatk
|
UTSW |
11 |
119,912,359 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6409:Aatk
|
UTSW |
11 |
119,902,558 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6477:Aatk
|
UTSW |
11 |
119,909,696 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6478:Aatk
|
UTSW |
11 |
119,901,817 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6749:Aatk
|
UTSW |
11 |
119,901,600 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R6753:Aatk
|
UTSW |
11 |
119,900,977 (GRCm39) |
missense |
probably benign |
|
|
R6787:Aatk
|
UTSW |
11 |
119,901,508 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6852:Aatk
|
UTSW |
11 |
119,901,294 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7114:Aatk
|
UTSW |
11 |
119,900,445 (GRCm39) |
missense |
probably benign |
|
|
R7557:Aatk
|
UTSW |
11 |
119,900,256 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R7818:Aatk
|
UTSW |
11 |
119,912,281 (GRCm39) |
missense |
probably benign |
|
|
R7954:Aatk
|
UTSW |
11 |
119,903,169 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R8176:Aatk
|
UTSW |
11 |
119,907,241 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8420:Aatk
|
UTSW |
11 |
119,937,746 (GRCm39) |
missense |
unknown |
|
|
R9090:Aatk
|
UTSW |
11 |
119,901,940 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9167:Aatk
|
UTSW |
11 |
119,901,952 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9271:Aatk
|
UTSW |
11 |
119,901,940 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9357:Aatk
|
UTSW |
11 |
119,901,696 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9373:Aatk
|
UTSW |
11 |
119,906,343 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9420:Aatk
|
UTSW |
11 |
119,912,277 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9423:Aatk
|
UTSW |
11 |
119,901,520 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9476:Aatk
|
UTSW |
11 |
119,901,094 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9510:Aatk
|
UTSW |
11 |
119,901,094 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9519:Aatk
|
UTSW |
11 |
119,912,309 (GRCm39) |
start gained |
probably benign |
|
|
R9605:Aatk
|
UTSW |
11 |
119,902,209 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R9649:Aatk
|
UTSW |
11 |
119,901,733 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9766:Aatk
|
UTSW |
11 |
119,902,565 (GRCm39) |
missense |
probably benign |
0.00 |
|
X0064:Aatk
|
UTSW |
11 |
119,902,002 (GRCm39) |
splice site |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- AAGTACTCGCTACCCACTGAGG -3'
(R):5'- TCCTACTTGTGTGCTAAGGGC -3'
Sequencing Primer
(F):5'- GGGCTGTGGGCACTGAG -3'
(R):5'- CCACAGAATTGGAGGAGGAGTTTG -3'
|
| Posted On |
2021-08-31 |
Incidental Mutation