Incidental Mutation 'R6478:Aatk'
| ID |
516926 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Aatk
|
| Ensembl Gene |
ENSMUSG00000025375 |
| Gene Name |
apoptosis-associated tyrosine kinase |
| Synonyms |
AATYK1 |
| MMRRC Submission |
044610-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.135)
|
| Stock # |
R6478 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
11 |
| Chromosomal Location |
119898139-119937993 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 119901817 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Cysteine
at position 803
(S803C)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000099309
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000026436]
[ENSMUST00000064307]
[ENSMUST00000103019]
[ENSMUST00000103020]
[ENSMUST00000106233]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000026436
|
| SMART Domains |
Protein: ENSMUSP00000026436
Gene: ENSMUSG00000025372
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:IMD
|
17 |
237 |
6e-101 |
PFAM |
|
PDB:4JS0|B
|
261 |
292 |
2e-13 |
PDB |
|
low complexity region
|
321 |
335 |
N/A |
INTRINSIC |
|
SH3
|
378 |
437 |
9.77e-11 |
SMART |
|
low complexity region
|
459 |
471 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000064307
AA Change: S860C
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000067181
Gene: ENSMUSG00000025375
AA Change: S860C
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
low complexity region
|
30 |
49 |
N/A |
INTRINSIC |
|
Pfam:Pkinase_Tyr
|
135 |
405 |
3.9e-63 |
PFAM |
|
Pfam:Pkinase
|
136 |
404 |
2.6e-33 |
PFAM |
|
low complexity region
|
425 |
457 |
N/A |
INTRINSIC |
|
low complexity region
|
502 |
514 |
N/A |
INTRINSIC |
|
low complexity region
|
615 |
624 |
N/A |
INTRINSIC |
|
low complexity region
|
647 |
666 |
N/A |
INTRINSIC |
|
low complexity region
|
684 |
695 |
N/A |
INTRINSIC |
|
low complexity region
|
808 |
819 |
N/A |
INTRINSIC |
|
low complexity region
|
913 |
927 |
N/A |
INTRINSIC |
|
low complexity region
|
934 |
943 |
N/A |
INTRINSIC |
|
low complexity region
|
985 |
1004 |
N/A |
INTRINSIC |
|
low complexity region
|
1063 |
1082 |
N/A |
INTRINSIC |
|
low complexity region
|
1085 |
1096 |
N/A |
INTRINSIC |
|
low complexity region
|
1160 |
1174 |
N/A |
INTRINSIC |
|
low complexity region
|
1179 |
1204 |
N/A |
INTRINSIC |
|
low complexity region
|
1319 |
1333 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000083666
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000103019
AA Change: S803C
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000099308
Gene: ENSMUSG00000025375
AA Change: S803C
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Pkinase
|
78 |
347 |
3e-36 |
PFAM |
|
Pfam:Pkinase_Tyr
|
78 |
348 |
1.9e-62 |
PFAM |
|
low complexity region
|
368 |
400 |
N/A |
INTRINSIC |
|
low complexity region
|
445 |
457 |
N/A |
INTRINSIC |
|
low complexity region
|
558 |
567 |
N/A |
INTRINSIC |
|
low complexity region
|
590 |
609 |
N/A |
INTRINSIC |
|
low complexity region
|
627 |
638 |
N/A |
INTRINSIC |
|
low complexity region
|
751 |
762 |
N/A |
INTRINSIC |
|
low complexity region
|
856 |
870 |
N/A |
INTRINSIC |
|
low complexity region
|
877 |
886 |
N/A |
INTRINSIC |
|
low complexity region
|
928 |
947 |
N/A |
INTRINSIC |
|
low complexity region
|
1006 |
1025 |
N/A |
INTRINSIC |
|
low complexity region
|
1028 |
1039 |
N/A |
INTRINSIC |
|
low complexity region
|
1103 |
1117 |
N/A |
INTRINSIC |
|
low complexity region
|
1122 |
1147 |
N/A |
INTRINSIC |
|
low complexity region
|
1262 |
1276 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000103020
AA Change: S803C
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000099309
Gene: ENSMUSG00000025375
AA Change: S803C
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Pkinase
|
78 |
347 |
3e-36 |
PFAM |
|
Pfam:Pkinase_Tyr
|
78 |
348 |
1.9e-62 |
PFAM |
|
low complexity region
|
368 |
400 |
N/A |
INTRINSIC |
|
low complexity region
|
445 |
457 |
N/A |
INTRINSIC |
|
low complexity region
|
558 |
567 |
N/A |
INTRINSIC |
|
low complexity region
|
590 |
609 |
N/A |
INTRINSIC |
|
low complexity region
|
627 |
638 |
N/A |
INTRINSIC |
|
low complexity region
|
751 |
762 |
N/A |
INTRINSIC |
|
low complexity region
|
856 |
870 |
N/A |
INTRINSIC |
|
low complexity region
|
877 |
886 |
N/A |
INTRINSIC |
|
low complexity region
|
928 |
947 |
N/A |
INTRINSIC |
|
low complexity region
|
1006 |
1025 |
N/A |
INTRINSIC |
|
low complexity region
|
1028 |
1039 |
N/A |
INTRINSIC |
|
low complexity region
|
1103 |
1117 |
N/A |
INTRINSIC |
|
low complexity region
|
1122 |
1147 |
N/A |
INTRINSIC |
|
low complexity region
|
1262 |
1276 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000106233
|
| SMART Domains |
Protein: ENSMUSP00000101840
Gene: ENSMUSG00000025372
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:IMD
|
17 |
237 |
1.6e-98 |
PFAM |
|
PDB:4JS0|B
|
261 |
292 |
8e-14 |
PDB |
|
low complexity region
|
321 |
335 |
N/A |
INTRINSIC |
|
SH3
|
378 |
437 |
9.77e-11 |
SMART |
|
low complexity region
|
459 |
471 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000128836
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000136386
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000132575
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000142959
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000150730
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000198674
|
| Meta Mutation Damage Score |
0.0634 |
| Coding Region Coverage |
- 1x: 99.9%
- 3x: 99.6%
- 10x: 97.8%
- 20x: 93.3%
|
| Validation Efficiency |
95% (75/79) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased brain size, longer axons and fewer neurites. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 78 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcc9 |
C |
T |
6: 142,625,034 (GRCm39) |
A454T |
probably damaging |
Het |
| Abr |
T |
C |
11: 76,343,158 (GRCm39) |
E565G |
probably damaging |
Het |
| Adam33 |
C |
A |
2: 130,893,266 (GRCm39) |
R753L |
probably benign |
Het |
| Adgre1 |
A |
G |
17: 57,708,955 (GRCm39) |
T49A |
possibly damaging |
Het |
| Ankra2 |
A |
T |
13: 98,404,950 (GRCm39) |
H153L |
probably damaging |
Het |
| Ankrd26 |
T |
G |
6: 118,488,599 (GRCm39) |
E1353D |
probably benign |
Het |
| Ankrd52 |
T |
G |
10: 128,215,200 (GRCm39) |
|
probably null |
Het |
| Arhgef10l |
T |
A |
4: 140,270,068 (GRCm39) |
T619S |
possibly damaging |
Het |
| Armh4 |
A |
G |
14: 50,010,789 (GRCm39) |
V306A |
possibly damaging |
Het |
| Asgr1 |
T |
C |
11: 69,947,720 (GRCm39) |
V130A |
possibly damaging |
Het |
| Atg10 |
C |
A |
13: 91,085,466 (GRCm39) |
C161F |
probably damaging |
Het |
| Atm |
A |
T |
9: 53,401,554 (GRCm39) |
N1438K |
probably damaging |
Het |
| BC107364 |
T |
A |
3: 96,343,322 (GRCm39) |
|
probably null |
Het |
| Bcar3 |
G |
T |
3: 122,220,225 (GRCm39) |
A41S |
probably benign |
Het |
| Btbd6 |
A |
G |
12: 112,940,932 (GRCm39) |
|
probably benign |
Het |
| Cchcr1 |
A |
G |
17: 35,835,600 (GRCm39) |
T318A |
possibly damaging |
Het |
| Celsr1 |
A |
T |
15: 85,809,719 (GRCm39) |
I2221N |
probably damaging |
Het |
| Cept1 |
C |
T |
3: 106,440,761 (GRCm39) |
W48* |
probably null |
Het |
| Cfap161 |
T |
A |
7: 83,442,484 (GRCm39) |
I85L |
probably benign |
Het |
| Clasp1 |
A |
T |
1: 118,439,910 (GRCm39) |
R640* |
probably null |
Het |
| Col5a1 |
T |
A |
2: 27,842,448 (GRCm39) |
I441N |
unknown |
Het |
| Col9a1 |
C |
A |
1: 24,224,486 (GRCm39) |
L223I |
unknown |
Het |
| Dnah2 |
T |
C |
11: 69,406,836 (GRCm39) |
D223G |
probably benign |
Het |
| Dnah8 |
G |
A |
17: 30,967,542 (GRCm39) |
D2585N |
probably benign |
Het |
| Dpy19l1 |
A |
T |
9: 24,361,992 (GRCm39) |
M129K |
possibly damaging |
Het |
| Ecpas |
A |
T |
4: 58,810,785 (GRCm39) |
I1524N |
probably damaging |
Het |
| Fcgbpl1 |
C |
G |
7: 27,854,798 (GRCm39) |
P1808R |
probably damaging |
Het |
| Fcrl1 |
C |
A |
3: 87,296,946 (GRCm39) |
H318Q |
probably benign |
Het |
| Fer1l5 |
A |
G |
1: 36,441,612 (GRCm39) |
N609S |
probably damaging |
Het |
| Fkbp4 |
C |
T |
6: 128,410,194 (GRCm39) |
E256K |
probably damaging |
Het |
| Fsip2 |
A |
G |
2: 82,820,430 (GRCm39) |
T5388A |
possibly damaging |
Het |
| Glrx |
G |
A |
13: 75,995,418 (GRCm39) |
|
probably null |
Het |
| Gm7356 |
A |
T |
17: 14,221,726 (GRCm39) |
M101K |
probably damaging |
Het |
| Gstp2 |
A |
T |
19: 4,090,499 (GRCm39) |
I162N |
probably benign |
Het |
| Hectd3 |
A |
C |
4: 116,856,783 (GRCm39) |
K443N |
probably damaging |
Het |
| Hmcn1 |
T |
A |
1: 150,540,535 (GRCm39) |
R2925W |
probably damaging |
Het |
| Hspa1a |
G |
T |
17: 35,189,282 (GRCm39) |
N540K |
probably damaging |
Het |
| Ints6 |
A |
T |
14: 62,938,235 (GRCm39) |
M649K |
probably benign |
Het |
| Katnb1 |
T |
C |
8: 95,822,084 (GRCm39) |
V270A |
possibly damaging |
Het |
| Kctd3 |
A |
G |
1: 188,704,561 (GRCm39) |
S737P |
probably benign |
Het |
| Klra10 |
T |
C |
6: 130,249,507 (GRCm39) |
|
probably null |
Het |
| Lmtk3 |
A |
G |
7: 45,448,013 (GRCm39) |
D1353G |
unknown |
Het |
| Lrrk1 |
A |
G |
7: 65,912,481 (GRCm39) |
V1693A |
probably damaging |
Het |
| Mpnd |
A |
T |
17: 56,316,575 (GRCm39) |
I85F |
probably damaging |
Het |
| Myo3b |
A |
G |
2: 70,179,304 (GRCm39) |
T1173A |
probably benign |
Het |
| Myof |
G |
A |
19: 37,892,279 (GRCm39) |
P1158L |
probably damaging |
Het |
| Naip2 |
A |
C |
13: 100,298,549 (GRCm39) |
S496A |
probably benign |
Het |
| Ncor2 |
A |
G |
5: 125,187,069 (GRCm39) |
|
probably benign |
Het |
| Npepps |
C |
T |
11: 97,149,099 (GRCm39) |
|
probably null |
Het |
| Opn5 |
T |
A |
17: 42,891,640 (GRCm39) |
I266F |
probably benign |
Het |
| Or4a74 |
T |
G |
2: 89,439,790 (GRCm39) |
I219L |
probably damaging |
Het |
| P2rx4 |
A |
G |
5: 122,845,763 (GRCm39) |
D16G |
probably damaging |
Het |
| Padi2 |
G |
T |
4: 140,644,948 (GRCm39) |
V61L |
probably benign |
Het |
| Pkd1l1 |
G |
A |
11: 8,813,911 (GRCm39) |
T1480I |
probably benign |
Het |
| Plcb1 |
T |
C |
2: 135,177,371 (GRCm39) |
S568P |
probably damaging |
Het |
| Rassf10 |
A |
G |
7: 112,554,914 (GRCm39) |
E505G |
probably damaging |
Het |
| Rcan2 |
A |
G |
17: 44,147,225 (GRCm39) |
E21G |
probably benign |
Het |
| Rhob |
G |
T |
12: 8,549,585 (GRCm39) |
C16* |
probably null |
Het |
| Ryr3 |
T |
C |
2: 112,490,413 (GRCm39) |
N3807S |
probably damaging |
Het |
| Sass6 |
T |
A |
3: 116,415,046 (GRCm39) |
N519K |
probably benign |
Het |
| Slco1a8 |
A |
T |
6: 141,939,368 (GRCm39) |
N208K |
possibly damaging |
Het |
| Smad9 |
A |
T |
3: 54,689,864 (GRCm39) |
D28V |
probably damaging |
Het |
| Spmip8 |
A |
T |
8: 96,047,894 (GRCm39) |
|
probably null |
Het |
| Tex14 |
G |
T |
11: 87,405,199 (GRCm39) |
G704C |
probably benign |
Het |
| Tmc3 |
A |
G |
7: 83,271,524 (GRCm39) |
N892S |
probably benign |
Het |
| Tnfaip2 |
T |
A |
12: 111,412,097 (GRCm39) |
L166Q |
probably damaging |
Het |
| Triml2 |
A |
G |
8: 43,638,165 (GRCm39) |
|
probably null |
Het |
| Trio |
A |
G |
15: 27,856,193 (GRCm39) |
V666A |
probably benign |
Het |
| Tshz2 |
G |
T |
2: 169,726,584 (GRCm39) |
L393F |
probably damaging |
Het |
| Ttn |
T |
G |
2: 76,672,115 (GRCm39) |
|
probably benign |
Het |
| Tubb5 |
A |
G |
17: 36,146,734 (GRCm39) |
Y159H |
probably damaging |
Het |
| Umodl1 |
A |
G |
17: 31,178,129 (GRCm39) |
Y35C |
probably damaging |
Het |
| Utp4 |
T |
C |
8: 107,631,078 (GRCm39) |
|
probably null |
Het |
| Vmn1r60 |
A |
T |
7: 5,547,864 (GRCm39) |
C79S |
probably damaging |
Het |
| Wnt5b |
T |
C |
6: 119,410,751 (GRCm39) |
T230A |
probably damaging |
Het |
| Zfp618 |
A |
T |
4: 63,050,943 (GRCm39) |
I575F |
probably damaging |
Het |
| Zmym6 |
G |
T |
4: 127,017,176 (GRCm39) |
V894L |
possibly damaging |
Het |
| Zpbp |
T |
C |
11: 11,412,318 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Aatk |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00497:Aatk
|
APN |
11 |
119,901,012 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL00953:Aatk
|
APN |
11 |
119,902,047 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01019:Aatk
|
APN |
11 |
119,903,101 (GRCm39) |
missense |
probably benign |
|
|
IGL01758:Aatk
|
APN |
11 |
119,901,645 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
IGL02377:Aatk
|
APN |
11 |
119,937,689 (GRCm39) |
utr 5 prime |
probably benign |
|
|
IGL02902:Aatk
|
APN |
11 |
119,902,603 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03067:Aatk
|
APN |
11 |
119,900,909 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03116:Aatk
|
APN |
11 |
119,907,577 (GRCm39) |
missense |
probably benign |
0.14 |
|
IGL03279:Aatk
|
APN |
11 |
119,904,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03405:Aatk
|
APN |
11 |
119,907,229 (GRCm39) |
missense |
probably benign |
0.02 |
|
PIT4366001:Aatk
|
UTSW |
11 |
119,901,786 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
PIT4802001:Aatk
|
UTSW |
11 |
119,902,172 (GRCm39) |
missense |
probably benign |
|
|
R0101:Aatk
|
UTSW |
11 |
119,901,739 (GRCm39) |
missense |
probably benign |
0.19 |
|
R0497:Aatk
|
UTSW |
11 |
119,909,606 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0535:Aatk
|
UTSW |
11 |
119,901,019 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0638:Aatk
|
UTSW |
11 |
119,900,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0939:Aatk
|
UTSW |
11 |
119,902,969 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1475:Aatk
|
UTSW |
11 |
119,901,714 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1840:Aatk
|
UTSW |
11 |
119,904,558 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1865:Aatk
|
UTSW |
11 |
119,901,048 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1982:Aatk
|
UTSW |
11 |
119,904,340 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2027:Aatk
|
UTSW |
11 |
119,900,143 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2115:Aatk
|
UTSW |
11 |
119,900,562 (GRCm39) |
missense |
probably benign |
|
|
R2220:Aatk
|
UTSW |
11 |
119,903,003 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2264:Aatk
|
UTSW |
11 |
119,901,100 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2504:Aatk
|
UTSW |
11 |
119,909,681 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3872:Aatk
|
UTSW |
11 |
119,901,045 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R4551:Aatk
|
UTSW |
11 |
119,902,395 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4657:Aatk
|
UTSW |
11 |
119,904,304 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R4744:Aatk
|
UTSW |
11 |
119,906,948 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R4924:Aatk
|
UTSW |
11 |
119,902,351 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5063:Aatk
|
UTSW |
11 |
119,901,315 (GRCm39) |
missense |
probably benign |
0.07 |
|
R5223:Aatk
|
UTSW |
11 |
119,904,278 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5243:Aatk
|
UTSW |
11 |
119,907,594 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5376:Aatk
|
UTSW |
11 |
119,902,860 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5442:Aatk
|
UTSW |
11 |
119,909,594 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5550:Aatk
|
UTSW |
11 |
119,900,129 (GRCm39) |
missense |
probably benign |
0.42 |
|
R5678:Aatk
|
UTSW |
11 |
119,900,980 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5932:Aatk
|
UTSW |
11 |
119,912,359 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6026:Aatk
|
UTSW |
11 |
119,903,190 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R6129:Aatk
|
UTSW |
11 |
119,912,359 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6409:Aatk
|
UTSW |
11 |
119,902,558 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6477:Aatk
|
UTSW |
11 |
119,909,696 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6749:Aatk
|
UTSW |
11 |
119,901,600 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R6753:Aatk
|
UTSW |
11 |
119,900,977 (GRCm39) |
missense |
probably benign |
|
|
R6787:Aatk
|
UTSW |
11 |
119,901,508 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6852:Aatk
|
UTSW |
11 |
119,901,294 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7114:Aatk
|
UTSW |
11 |
119,900,445 (GRCm39) |
missense |
probably benign |
|
|
R7557:Aatk
|
UTSW |
11 |
119,900,256 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R7818:Aatk
|
UTSW |
11 |
119,912,281 (GRCm39) |
missense |
probably benign |
|
|
R7954:Aatk
|
UTSW |
11 |
119,903,169 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R8176:Aatk
|
UTSW |
11 |
119,907,241 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8420:Aatk
|
UTSW |
11 |
119,937,746 (GRCm39) |
missense |
unknown |
|
|
R8963:Aatk
|
UTSW |
11 |
119,902,963 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9090:Aatk
|
UTSW |
11 |
119,901,940 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9167:Aatk
|
UTSW |
11 |
119,901,952 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9271:Aatk
|
UTSW |
11 |
119,901,940 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9357:Aatk
|
UTSW |
11 |
119,901,696 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9373:Aatk
|
UTSW |
11 |
119,906,343 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9420:Aatk
|
UTSW |
11 |
119,912,277 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9423:Aatk
|
UTSW |
11 |
119,901,520 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9476:Aatk
|
UTSW |
11 |
119,901,094 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9510:Aatk
|
UTSW |
11 |
119,901,094 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9519:Aatk
|
UTSW |
11 |
119,912,309 (GRCm39) |
start gained |
probably benign |
|
|
R9605:Aatk
|
UTSW |
11 |
119,902,209 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R9649:Aatk
|
UTSW |
11 |
119,901,733 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9766:Aatk
|
UTSW |
11 |
119,902,565 (GRCm39) |
missense |
probably benign |
0.00 |
|
X0064:Aatk
|
UTSW |
11 |
119,902,002 (GRCm39) |
splice site |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- ACGGTATGTCCAGAGAGTCC -3'
(R):5'- GAGAACCCCATTGTGGAACC -3'
Sequencing Primer
(F):5'- TATGTCCAGAGAGTCCAGGGAGTC -3'
(R):5'- TTGTGGAACCCAAACTTGCC -3'
|
| Posted On |
2018-05-21 |
Incidental Mutation