Incidental Mutation 'R9278:Phldb2'
| ID |
703467 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Phldb2
|
| Ensembl Gene |
ENSMUSG00000033149 |
| Gene Name |
pleckstrin homology like domain, family B, member 2 |
| Synonyms |
LL5b, C820004H04Rik, LL5beta |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R9278 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
16 |
| Chromosomal Location |
45566606-45773961 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to A
at 45646308 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Isoleucine
at position 46
(S46I)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000075672
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000036355]
[ENSMUST00000076333]
[ENSMUST00000134802]
[ENSMUST00000136405]
|
| AlphaFold |
Q8K1N2 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000036355
AA Change: S46I
PolyPhen 2
Score 0.967 (Sensitivity: 0.77; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000046496
Gene: ENSMUSG00000033149
AA Change: S46I
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
267 |
283 |
N/A |
INTRINSIC |
|
low complexity region
|
426 |
447 |
N/A |
INTRINSIC |
|
coiled coil region
|
580 |
692 |
N/A |
INTRINSIC |
|
coiled coil region
|
724 |
800 |
N/A |
INTRINSIC |
|
coiled coil region
|
1027 |
1097 |
N/A |
INTRINSIC |
|
PH
|
1140 |
1244 |
6.45e-17 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000076333
AA Change: S46I
PolyPhen 2
Score 0.989 (Sensitivity: 0.72; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000075672
Gene: ENSMUSG00000033149
AA Change: S46I
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
267 |
283 |
N/A |
INTRINSIC |
|
low complexity region
|
426 |
447 |
N/A |
INTRINSIC |
|
coiled coil region
|
580 |
692 |
N/A |
INTRINSIC |
|
coiled coil region
|
724 |
800 |
N/A |
INTRINSIC |
|
low complexity region
|
901 |
913 |
N/A |
INTRINSIC |
|
coiled coil region
|
1080 |
1150 |
N/A |
INTRINSIC |
|
PH
|
1193 |
1297 |
6.45e-17 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000134802
AA Change: S91I
PolyPhen 2
Score 0.989 (Sensitivity: 0.72; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000123284
Gene: ENSMUSG00000033149
AA Change: S91I
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
20 |
28 |
N/A |
INTRINSIC |
|
low complexity region
|
312 |
328 |
N/A |
INTRINSIC |
|
low complexity region
|
471 |
492 |
N/A |
INTRINSIC |
|
coiled coil region
|
625 |
737 |
N/A |
INTRINSIC |
|
coiled coil region
|
769 |
845 |
N/A |
INTRINSIC |
|
coiled coil region
|
1072 |
1131 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000136405
AA Change: S87I
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000121800
Gene: ENSMUSG00000033149
AA Change: S87I
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
16 |
24 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.1130 |
| Coding Region Coverage |
- 1x: 93.4%
- 3x: 93.4%
- 10x: 93.2%
- 20x: 92.9%
|
| Validation Efficiency |
97% (77/79) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 79 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Afdn |
T |
A |
17: 14,024,270 (GRCm39) |
C59S |
probably damaging |
Het |
| Aicda |
C |
T |
6: 122,538,854 (GRCm39) |
A161V |
possibly damaging |
Het |
| Ankrd12 |
C |
T |
17: 66,344,599 (GRCm39) |
E91K |
possibly damaging |
Het |
| Arpc2 |
C |
A |
1: 74,276,041 (GRCm39) |
F19L |
probably benign |
Het |
| Aspa |
T |
C |
11: 73,215,280 (GRCm39) |
K12E |
possibly damaging |
Het |
| Chd8 |
G |
A |
14: 52,472,627 (GRCm39) |
P392L |
probably benign |
Het |
| Cldn10 |
C |
T |
14: 119,111,647 (GRCm39) |
R206W |
probably damaging |
Het |
| Clec4b2 |
T |
A |
6: 123,181,224 (GRCm39) |
M203K |
probably damaging |
Het |
| Clec4d |
G |
T |
6: 123,251,651 (GRCm39) |
E178* |
probably null |
Het |
| Clec4d |
T |
C |
6: 123,251,649 (GRCm39) |
M177T |
probably benign |
Het |
| Cmpk2 |
A |
T |
12: 26,519,568 (GRCm39) |
Y73F |
probably benign |
Het |
| Col1a1 |
T |
A |
11: 94,838,103 (GRCm39) |
V845D |
unknown |
Het |
| Cyp2c67 |
C |
T |
19: 39,597,699 (GRCm39) |
R433Q |
probably damaging |
Het |
| Dda1 |
A |
T |
8: 71,927,130 (GRCm39) |
|
probably null |
Het |
| Ddx60 |
A |
T |
8: 62,431,012 (GRCm39) |
Y849F |
possibly damaging |
Het |
| Dnm2 |
C |
T |
9: 21,416,977 (GRCm39) |
R837W |
possibly damaging |
Het |
| Dtwd1 |
C |
T |
2: 126,006,728 (GRCm39) |
T250I |
probably damaging |
Het |
| Efcab6 |
A |
G |
15: 83,777,094 (GRCm39) |
V1114A |
probably damaging |
Het |
| Fat4 |
A |
G |
3: 38,945,171 (GRCm39) |
T1355A |
probably benign |
Het |
| Fbxo40 |
T |
G |
16: 36,789,940 (GRCm39) |
D390A |
possibly damaging |
Het |
| Gnaz |
T |
A |
10: 74,827,437 (GRCm39) |
L63Q |
probably benign |
Het |
| H6pd |
T |
A |
4: 150,080,307 (GRCm39) |
K179N |
probably damaging |
Het |
| Hmgb2 |
A |
G |
8: 57,965,786 (GRCm39) |
|
probably benign |
Het |
| Hps5 |
A |
G |
7: 46,440,397 (GRCm39) |
F18L |
probably benign |
Het |
| Hyal5 |
A |
G |
6: 24,876,694 (GRCm39) |
E189G |
probably benign |
Het |
| Ifnar1 |
T |
A |
16: 91,302,013 (GRCm39) |
I496N |
probably damaging |
Het |
| Ift70a2 |
T |
C |
2: 75,807,375 (GRCm39) |
D379G |
probably damaging |
Het |
| Igf2r |
C |
A |
17: 12,914,240 (GRCm39) |
C1743F |
probably damaging |
Het |
| Igfn1 |
C |
A |
1: 135,901,185 (GRCm39) |
R431L |
probably damaging |
Het |
| Itch |
A |
G |
2: 155,045,217 (GRCm39) |
Q507R |
probably benign |
Het |
| Kbtbd2 |
C |
A |
6: 56,757,331 (GRCm39) |
R135L |
probably damaging |
Het |
| Kcnn2 |
T |
C |
18: 45,725,446 (GRCm39) |
I314T |
probably damaging |
Het |
| Lix1 |
A |
G |
17: 17,623,211 (GRCm39) |
D2G |
probably damaging |
Het |
| Lrp1b |
T |
C |
2: 40,487,076 (GRCm39) |
Y4557C |
|
Het |
| Ltbp2 |
G |
A |
12: 84,837,864 (GRCm39) |
P1192L |
probably benign |
Het |
| Mcam |
G |
T |
9: 44,046,473 (GRCm39) |
|
probably benign |
Het |
| Med19 |
G |
T |
2: 84,508,975 (GRCm39) |
G63C |
probably damaging |
Het |
| Mfsd4b1 |
C |
T |
10: 39,883,330 (GRCm39) |
R40H |
probably damaging |
Het |
| Neb |
C |
T |
2: 52,146,190 (GRCm39) |
R2929H |
probably damaging |
Het |
| Nlrc5 |
A |
G |
8: 95,237,908 (GRCm39) |
D1434G |
probably benign |
Het |
| Nlrp14 |
A |
T |
7: 106,797,049 (GRCm39) |
N972I |
probably damaging |
Het |
| Or13a18 |
T |
C |
7: 140,190,936 (GRCm39) |
Y278H |
probably damaging |
Het |
| Or14j7 |
A |
T |
17: 38,235,275 (GRCm39) |
M273L |
probably benign |
Het |
| Or2h15 |
A |
T |
17: 38,441,693 (GRCm39) |
L130Q |
probably damaging |
Het |
| Or4a74 |
A |
C |
2: 89,439,948 (GRCm39) |
F166C |
probably damaging |
Het |
| Or8g29-ps1 |
A |
G |
9: 39,200,781 (GRCm39) |
V135A |
probably benign |
Het |
| Otop1 |
T |
C |
5: 38,460,158 (GRCm39) |
V575A |
probably damaging |
Het |
| Pcdhb4 |
A |
G |
18: 37,441,925 (GRCm39) |
S412G |
possibly damaging |
Het |
| Pcsk4 |
T |
C |
10: 80,161,224 (GRCm39) |
D230G |
probably damaging |
Het |
| Pik3ca |
A |
T |
3: 32,508,587 (GRCm39) |
N785I |
probably damaging |
Het |
| Polr2b |
A |
G |
5: 77,471,485 (GRCm39) |
R274G |
probably damaging |
Het |
| Prkdc |
G |
A |
16: 15,634,523 (GRCm39) |
|
probably null |
Het |
| Prune2 |
C |
T |
19: 17,101,144 (GRCm39) |
T2216I |
probably benign |
Het |
| Psma3 |
A |
T |
12: 71,041,156 (GRCm39) |
D252V |
probably benign |
Het |
| Rnf213 |
T |
C |
11: 119,326,768 (GRCm39) |
V1586A |
|
Het |
| Ryr2 |
T |
C |
13: 11,897,976 (GRCm39) |
T140A |
probably benign |
Het |
| Slc25a48 |
A |
G |
13: 56,611,552 (GRCm39) |
I220V |
probably benign |
Het |
| Slc2a1 |
A |
T |
4: 118,990,607 (GRCm39) |
E246D |
probably benign |
Het |
| Slc45a4 |
A |
G |
15: 73,458,206 (GRCm39) |
Y448H |
probably benign |
Het |
| Sorl1 |
C |
T |
9: 41,957,857 (GRCm39) |
V596I |
probably benign |
Het |
| Spag6 |
A |
C |
2: 18,703,985 (GRCm39) |
E11A |
probably benign |
Het |
| Spef2 |
A |
G |
15: 9,727,495 (GRCm39) |
|
probably null |
Het |
| Spon1 |
T |
C |
7: 113,628,188 (GRCm39) |
S315P |
probably damaging |
Het |
| Stard3 |
G |
A |
11: 98,262,931 (GRCm39) |
|
probably benign |
Het |
| Sv2c |
A |
G |
13: 96,112,589 (GRCm39) |
M636T |
probably damaging |
Het |
| Syt17 |
T |
A |
7: 118,033,480 (GRCm39) |
D172V |
probably damaging |
Het |
| Tcf4 |
A |
G |
18: 69,766,652 (GRCm39) |
Y206C |
probably damaging |
Het |
| Tead2 |
G |
T |
7: 44,880,776 (GRCm39) |
S318I |
probably benign |
Het |
| Tom1 |
A |
T |
8: 75,783,883 (GRCm39) |
D289V |
probably damaging |
Het |
| Tonsl |
A |
G |
15: 76,520,971 (GRCm39) |
|
probably benign |
Het |
| Tsen15 |
T |
C |
1: 152,259,098 (GRCm39) |
I87V |
probably damaging |
Het |
| Usp15 |
A |
G |
10: 123,007,112 (GRCm39) |
F123S |
probably damaging |
Het |
| Vmn1r220 |
A |
T |
13: 23,368,258 (GRCm39) |
I146N |
possibly damaging |
Het |
| Vmn2r108 |
A |
T |
17: 20,692,561 (GRCm39) |
N98K |
probably benign |
Het |
| Vmn2r71 |
T |
A |
7: 85,269,788 (GRCm39) |
M433K |
probably benign |
Het |
| Vmn2r97 |
A |
T |
17: 19,134,762 (GRCm39) |
H60L |
probably benign |
Het |
| Wbp4 |
A |
G |
14: 79,699,486 (GRCm39) |
V336A |
probably benign |
Het |
| Zfp663 |
T |
C |
2: 165,202,010 (GRCm39) |
|
probably null |
Het |
| Zpld2 |
A |
G |
4: 133,922,770 (GRCm39) |
L521P |
probably damaging |
Het |
|
| Other mutations in Phldb2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00321:Phldb2
|
APN |
16 |
45,592,617 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00485:Phldb2
|
APN |
16 |
45,577,551 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
IGL00544:Phldb2
|
APN |
16 |
45,645,674 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00547:Phldb2
|
APN |
16 |
45,645,898 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00835:Phldb2
|
APN |
16 |
45,571,819 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00987:Phldb2
|
APN |
16 |
45,583,465 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
IGL01102:Phldb2
|
APN |
16 |
45,645,423 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01530:Phldb2
|
APN |
16 |
45,623,092 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01549:Phldb2
|
APN |
16 |
45,594,681 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01712:Phldb2
|
APN |
16 |
45,571,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01755:Phldb2
|
APN |
16 |
45,645,945 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01823:Phldb2
|
APN |
16 |
45,645,507 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02353:Phldb2
|
APN |
16 |
45,569,142 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02360:Phldb2
|
APN |
16 |
45,569,142 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02716:Phldb2
|
APN |
16 |
45,621,953 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0139:Phldb2
|
UTSW |
16 |
45,591,029 (GRCm39) |
splice site |
probably benign |
|
|
R0312:Phldb2
|
UTSW |
16 |
45,609,410 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0379:Phldb2
|
UTSW |
16 |
45,601,814 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0535:Phldb2
|
UTSW |
16 |
45,577,490 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1387:Phldb2
|
UTSW |
16 |
45,646,357 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R1444:Phldb2
|
UTSW |
16 |
45,577,616 (GRCm39) |
splice site |
probably benign |
|
|
R1487:Phldb2
|
UTSW |
16 |
45,609,387 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1501:Phldb2
|
UTSW |
16 |
45,598,146 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1605:Phldb2
|
UTSW |
16 |
45,591,142 (GRCm39) |
splice site |
probably benign |
|
|
R1716:Phldb2
|
UTSW |
16 |
45,595,413 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1732:Phldb2
|
UTSW |
16 |
45,577,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1779:Phldb2
|
UTSW |
16 |
45,621,988 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1824:Phldb2
|
UTSW |
16 |
45,646,374 (GRCm39) |
missense |
probably benign |
0.14 |
|
R2001:Phldb2
|
UTSW |
16 |
45,594,558 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R2066:Phldb2
|
UTSW |
16 |
45,591,121 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2122:Phldb2
|
UTSW |
16 |
45,583,304 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2448:Phldb2
|
UTSW |
16 |
45,645,726 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2932:Phldb2
|
UTSW |
16 |
45,569,148 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R3076:Phldb2
|
UTSW |
16 |
45,645,373 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3078:Phldb2
|
UTSW |
16 |
45,645,373 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3779:Phldb2
|
UTSW |
16 |
45,569,118 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3914:Phldb2
|
UTSW |
16 |
45,577,526 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4536:Phldb2
|
UTSW |
16 |
45,591,044 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4568:Phldb2
|
UTSW |
16 |
45,598,081 (GRCm39) |
nonsense |
probably null |
|
|
R4798:Phldb2
|
UTSW |
16 |
45,646,237 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4853:Phldb2
|
UTSW |
16 |
45,623,079 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4906:Phldb2
|
UTSW |
16 |
45,571,758 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4984:Phldb2
|
UTSW |
16 |
45,645,996 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5078:Phldb2
|
UTSW |
16 |
45,598,105 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R5137:Phldb2
|
UTSW |
16 |
45,628,621 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R5237:Phldb2
|
UTSW |
16 |
45,568,249 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5410:Phldb2
|
UTSW |
16 |
45,645,975 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R5825:Phldb2
|
UTSW |
16 |
45,583,460 (GRCm39) |
missense |
probably benign |
0.11 |
|
R5874:Phldb2
|
UTSW |
16 |
45,621,988 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5907:Phldb2
|
UTSW |
16 |
45,645,551 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6332:Phldb2
|
UTSW |
16 |
45,594,609 (GRCm39) |
missense |
probably benign |
|
|
R6354:Phldb2
|
UTSW |
16 |
45,645,477 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6355:Phldb2
|
UTSW |
16 |
45,645,701 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6383:Phldb2
|
UTSW |
16 |
45,569,113 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6463:Phldb2
|
UTSW |
16 |
45,595,356 (GRCm39) |
missense |
probably benign |
0.37 |
|
R6513:Phldb2
|
UTSW |
16 |
45,568,240 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R6593:Phldb2
|
UTSW |
16 |
45,645,790 (GRCm39) |
nonsense |
probably null |
|
|
R6756:Phldb2
|
UTSW |
16 |
45,628,683 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6810:Phldb2
|
UTSW |
16 |
45,569,088 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6897:Phldb2
|
UTSW |
16 |
45,598,138 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7010:Phldb2
|
UTSW |
16 |
45,571,868 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7142:Phldb2
|
UTSW |
16 |
45,577,539 (GRCm39) |
nonsense |
probably null |
|
|
R7149:Phldb2
|
UTSW |
16 |
45,571,895 (GRCm39) |
nonsense |
probably null |
|
|
R7249:Phldb2
|
UTSW |
16 |
45,621,977 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7300:Phldb2
|
UTSW |
16 |
45,645,925 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7328:Phldb2
|
UTSW |
16 |
45,578,572 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7515:Phldb2
|
UTSW |
16 |
45,594,603 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7840:Phldb2
|
UTSW |
16 |
45,571,727 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7988:Phldb2
|
UTSW |
16 |
45,645,934 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8159:Phldb2
|
UTSW |
16 |
45,680,747 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8353:Phldb2
|
UTSW |
16 |
45,645,385 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8453:Phldb2
|
UTSW |
16 |
45,645,385 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8969:Phldb2
|
UTSW |
16 |
45,592,496 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9058:Phldb2
|
UTSW |
16 |
45,592,604 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R9106:Phldb2
|
UTSW |
16 |
45,680,757 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9324:Phldb2
|
UTSW |
16 |
45,595,437 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9563:Phldb2
|
UTSW |
16 |
45,645,247 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9626:Phldb2
|
UTSW |
16 |
45,592,547 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R9712:Phldb2
|
UTSW |
16 |
45,595,340 (GRCm39) |
missense |
probably benign |
0.27 |
|
R9718:Phldb2
|
UTSW |
16 |
45,601,756 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
RF008:Phldb2
|
UTSW |
16 |
45,583,337 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Phldb2
|
UTSW |
16 |
45,773,871 (GRCm39) |
unclassified |
probably benign |
|
|
Z1176:Phldb2
|
UTSW |
16 |
45,646,190 (GRCm39) |
missense |
probably benign |
0.04 |
|
Z1176:Phldb2
|
UTSW |
16 |
45,646,189 (GRCm39) |
missense |
probably benign |
0.43 |
|
Z1190:Phldb2
|
UTSW |
16 |
45,645,697 (GRCm39) |
missense |
probably damaging |
0.96 |
|
| Predicted Primers |
PCR Primer
(F):5'- CTTTCCCAAGAGGATAGCCG -3'
(R):5'- GGTACACTTTCACGTGTGTTTAAAC -3'
Sequencing Primer
(F):5'- CCAAGAGGATAGCCGCCAAG -3'
(R):5'- CGTGTGTTTAAACTAAAACTTTCTCC -3'
|
| Posted On |
2022-03-25 |
Incidental Mutation