Incidental Mutation 'R1528:Nckap5'
| ID |
166321 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Nckap5
|
| Ensembl Gene |
ENSMUSG00000049690 |
| Gene Name |
NCK-associated protein 5 |
| Synonyms |
LOC380609, D130011D22Rik, E030049G20Rik |
| MMRRC Submission |
039568-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1528 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
1 |
| Chromosomal Location |
125841373-126758529 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 125952659 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Isoleucine
at position 1234
(V1234I)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000062229
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000057846]
[ENSMUST00000094609]
[ENSMUST00000094610]
[ENSMUST00000112583]
[ENSMUST00000161954]
[ENSMUST00000162877]
|
| AlphaFold |
E9QAE1 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000057846
AA Change: V1234I
PolyPhen 2
Score 0.678 (Sensitivity: 0.86; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000062229
Gene: ENSMUSG00000049690
AA Change: V1234I
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
25 |
N/A |
INTRINSIC |
|
coiled coil region
|
108 |
186 |
N/A |
INTRINSIC |
|
low complexity region
|
321 |
332 |
N/A |
INTRINSIC |
|
low complexity region
|
755 |
771 |
N/A |
INTRINSIC |
|
low complexity region
|
950 |
971 |
N/A |
INTRINSIC |
|
low complexity region
|
1070 |
1085 |
N/A |
INTRINSIC |
|
low complexity region
|
1181 |
1200 |
N/A |
INTRINSIC |
|
Pfam:NCKAP5
|
1298 |
1602 |
1.8e-120 |
PFAM |
|
low complexity region
|
1728 |
1742 |
N/A |
INTRINSIC |
|
low complexity region
|
1757 |
1771 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000094609
|
| SMART Domains |
Protein: ENSMUSP00000092192
Gene: ENSMUSG00000049690
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
70 |
93 |
N/A |
INTRINSIC |
|
Pfam:NCKAP5
|
113 |
364 |
3.6e-36 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000094610
|
| SMART Domains |
Protein: ENSMUSP00000092193
Gene: ENSMUSG00000049690
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:NCKAP5
|
1 |
101 |
8.8e-42 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000112583
AA Change: V1366I
PolyPhen 2
Score 0.022 (Sensitivity: 0.95; Specificity: 0.81)
|
| SMART Domains |
Protein: ENSMUSP00000108202
Gene: ENSMUSG00000049690
AA Change: V1366I
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
70 |
93 |
N/A |
INTRINSIC |
|
coiled coil region
|
176 |
254 |
N/A |
INTRINSIC |
|
low complexity region
|
301 |
324 |
N/A |
INTRINSIC |
|
low complexity region
|
453 |
464 |
N/A |
INTRINSIC |
|
low complexity region
|
887 |
903 |
N/A |
INTRINSIC |
|
low complexity region
|
1082 |
1103 |
N/A |
INTRINSIC |
|
low complexity region
|
1202 |
1217 |
N/A |
INTRINSIC |
|
low complexity region
|
1313 |
1332 |
N/A |
INTRINSIC |
|
Pfam:NCKAP5
|
1431 |
1733 |
5.3e-119 |
PFAM |
|
low complexity region
|
1860 |
1874 |
N/A |
INTRINSIC |
|
low complexity region
|
1889 |
1903 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000159934
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000161954
AA Change: V1298I
PolyPhen 2
Score 0.022 (Sensitivity: 0.95; Specificity: 0.81)
|
| SMART Domains |
Protein: ENSMUSP00000125624
Gene: ENSMUSG00000049690
AA Change: V1298I
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
25 |
N/A |
INTRINSIC |
|
coiled coil region
|
108 |
186 |
N/A |
INTRINSIC |
|
low complexity region
|
233 |
256 |
N/A |
INTRINSIC |
|
low complexity region
|
385 |
396 |
N/A |
INTRINSIC |
|
low complexity region
|
819 |
835 |
N/A |
INTRINSIC |
|
low complexity region
|
1014 |
1035 |
N/A |
INTRINSIC |
|
low complexity region
|
1134 |
1149 |
N/A |
INTRINSIC |
|
low complexity region
|
1245 |
1264 |
N/A |
INTRINSIC |
|
Pfam:NCKAP5
|
1362 |
1666 |
2.1e-120 |
PFAM |
|
low complexity region
|
1792 |
1806 |
N/A |
INTRINSIC |
|
low complexity region
|
1821 |
1835 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000162877
|
| SMART Domains |
Protein: ENSMUSP00000124748
Gene: ENSMUSG00000049690
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:NCKAP5
|
9 |
296 |
6e-36 |
PFAM |
|
| Coding Region Coverage |
- 1x: 99.4%
- 3x: 98.7%
- 10x: 97.3%
- 20x: 95.4%
|
| Validation Efficiency |
|
| Allele List at MGI |
All alleles(1) : Gene trapped(1) |
| Other mutations in this stock |
Total: 83 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2610008E11Rik |
T |
A |
10: 78,903,530 (GRCm39) |
Q262L |
possibly damaging |
Het |
| Abcg4 |
T |
C |
9: 44,186,020 (GRCm39) |
Y617C |
probably damaging |
Het |
| Amph |
G |
A |
13: 19,326,198 (GRCm39) |
V643M |
probably damaging |
Het |
| Ano1 |
T |
G |
7: 144,149,303 (GRCm39) |
S853R |
probably damaging |
Het |
| Ap4e1 |
T |
A |
2: 126,853,743 (GRCm39) |
S60R |
possibly damaging |
Het |
| Atp4b |
C |
A |
8: 13,439,693 (GRCm39) |
K176N |
possibly damaging |
Het |
| Atxn2 |
A |
T |
5: 121,940,171 (GRCm39) |
D982V |
probably damaging |
Het |
| Atxn2 |
T |
C |
5: 121,951,593 (GRCm39) |
F646S |
probably damaging |
Het |
| Bcl2l13 |
T |
C |
6: 120,847,755 (GRCm39) |
C136R |
possibly damaging |
Het |
| Bltp1 |
C |
T |
3: 37,106,684 (GRCm39) |
H5005Y |
unknown |
Het |
| Cacna1i |
A |
G |
15: 80,275,975 (GRCm39) |
|
probably null |
Het |
| Ccdc122 |
T |
A |
14: 77,305,379 (GRCm39) |
V11D |
possibly damaging |
Het |
| Cdnf |
A |
G |
2: 3,522,078 (GRCm39) |
D90G |
probably damaging |
Het |
| Cep104 |
T |
G |
4: 154,078,965 (GRCm39) |
V323G |
probably benign |
Het |
| Chmp6 |
A |
G |
11: 119,807,541 (GRCm39) |
D128G |
probably benign |
Het |
| Clec18a |
A |
T |
8: 111,805,498 (GRCm39) |
M201K |
probably benign |
Het |
| Col11a1 |
A |
T |
3: 114,010,644 (GRCm39) |
|
probably benign |
Het |
| Col6a4 |
A |
T |
9: 105,952,419 (GRCm39) |
M493K |
probably damaging |
Het |
| Crygd |
A |
C |
1: 65,102,216 (GRCm39) |
|
probably null |
Het |
| Dennd1c |
T |
C |
17: 57,373,935 (GRCm39) |
T543A |
probably benign |
Het |
| Erbb4 |
A |
T |
1: 68,117,741 (GRCm39) |
C891* |
probably null |
Het |
| Ercc5 |
A |
T |
1: 44,217,401 (GRCm39) |
K915* |
probably null |
Het |
| Ercc6 |
A |
T |
14: 32,240,979 (GRCm39) |
N168Y |
probably damaging |
Het |
| Esrp2 |
G |
T |
8: 106,863,384 (GRCm39) |
P6T |
unknown |
Het |
| Exoc1 |
A |
G |
5: 76,697,411 (GRCm39) |
K396R |
possibly damaging |
Het |
| Fat3 |
T |
A |
9: 15,836,387 (GRCm39) |
Y4039F |
probably benign |
Het |
| Fcsk |
A |
T |
8: 111,609,873 (GRCm39) |
L1047Q |
probably damaging |
Het |
| Fgf7 |
T |
A |
2: 125,877,738 (GRCm39) |
M35K |
probably damaging |
Het |
| Fras1 |
G |
A |
5: 96,784,678 (GRCm39) |
G887D |
probably damaging |
Het |
| Gbp4 |
A |
T |
5: 105,269,658 (GRCm39) |
|
probably null |
Het |
| Homez |
A |
T |
14: 55,095,162 (GRCm39) |
M182K |
probably benign |
Het |
| Hrnr |
G |
A |
3: 93,230,101 (GRCm39) |
S113N |
possibly damaging |
Het |
| Ifit3b |
T |
G |
19: 34,589,072 (GRCm39) |
S83A |
probably benign |
Het |
| Ildr2 |
A |
G |
1: 166,098,064 (GRCm39) |
|
probably null |
Het |
| Klhdc1 |
A |
T |
12: 69,309,972 (GRCm39) |
R291S |
probably benign |
Het |
| Krt77 |
T |
A |
15: 101,769,523 (GRCm39) |
I413F |
probably damaging |
Het |
| Lipn |
A |
G |
19: 34,046,070 (GRCm39) |
I14M |
probably damaging |
Het |
| Macf1 |
T |
G |
4: 123,369,807 (GRCm39) |
R86S |
probably benign |
Het |
| Mroh8 |
C |
A |
2: 157,071,975 (GRCm39) |
G510V |
probably damaging |
Het |
| Mycbp2 |
A |
T |
14: 103,470,033 (GRCm39) |
D1255E |
possibly damaging |
Het |
| Nlrp9c |
T |
C |
7: 26,081,723 (GRCm39) |
K668E |
probably damaging |
Het |
| Nod2 |
T |
C |
8: 89,391,217 (GRCm39) |
M508T |
possibly damaging |
Het |
| Npffr1 |
A |
G |
10: 61,450,016 (GRCm39) |
M97V |
possibly damaging |
Het |
| Nsd3 |
G |
A |
8: 26,188,795 (GRCm39) |
V43M |
probably damaging |
Het |
| Nubp2 |
A |
G |
17: 25,103,388 (GRCm39) |
V163A |
probably damaging |
Het |
| Oas1e |
A |
T |
5: 120,926,054 (GRCm39) |
F338Y |
probably damaging |
Het |
| Oat |
C |
A |
7: 132,165,998 (GRCm39) |
G196C |
probably damaging |
Het |
| Or4a69 |
C |
T |
2: 89,312,897 (GRCm39) |
G194D |
probably damaging |
Het |
| Or52e8b |
A |
T |
7: 104,673,971 (GRCm39) |
L72Q |
probably damaging |
Het |
| Or7a41 |
T |
C |
10: 78,871,398 (GRCm39) |
L256P |
probably damaging |
Het |
| P2ry13 |
T |
C |
3: 59,117,710 (GRCm39) |
T23A |
probably benign |
Het |
| Phf8-ps |
A |
G |
17: 33,286,215 (GRCm39) |
S196P |
probably damaging |
Het |
| Pja2 |
C |
A |
17: 64,616,217 (GRCm39) |
S226I |
possibly damaging |
Het |
| Pkhd1l1 |
T |
C |
15: 44,390,120 (GRCm39) |
V1412A |
probably damaging |
Het |
| Plekhs1 |
T |
C |
19: 56,468,427 (GRCm39) |
S332P |
probably damaging |
Het |
| Polr3e |
T |
A |
7: 120,539,820 (GRCm39) |
N522K |
probably damaging |
Het |
| Prdm10 |
A |
G |
9: 31,268,582 (GRCm39) |
T844A |
probably damaging |
Het |
| Ripk1 |
C |
T |
13: 34,212,130 (GRCm39) |
P480L |
probably benign |
Het |
| Rnf139 |
T |
C |
15: 58,771,064 (GRCm39) |
V363A |
probably damaging |
Het |
| Rnf19a |
A |
T |
15: 36,265,801 (GRCm39) |
S99T |
possibly damaging |
Het |
| Rnf224 |
G |
A |
2: 25,126,110 (GRCm39) |
T81I |
probably benign |
Het |
| Rpgrip1 |
T |
C |
14: 52,349,681 (GRCm39) |
L23S |
probably benign |
Het |
| Setd5 |
T |
A |
6: 113,098,699 (GRCm39) |
F758L |
probably damaging |
Het |
| Smlr1 |
C |
A |
10: 25,411,976 (GRCm39) |
V4L |
possibly damaging |
Het |
| Snx1 |
T |
C |
9: 66,016,825 (GRCm39) |
D34G |
probably damaging |
Het |
| Spaca5 |
A |
T |
X: 20,942,892 (GRCm39) |
T92S |
probably benign |
Het |
| Speer4f2 |
A |
G |
5: 17,581,540 (GRCm39) |
T161A |
|
Het |
| Swi5 |
C |
A |
2: 32,170,716 (GRCm39) |
|
probably null |
Het |
| Syne2 |
T |
A |
12: 76,012,874 (GRCm39) |
D2689E |
probably benign |
Het |
| Tcof1 |
T |
A |
18: 60,948,071 (GRCm39) |
K1299* |
probably null |
Het |
| Tmprss11e |
G |
A |
5: 86,872,069 (GRCm39) |
T49I |
probably damaging |
Het |
| Tmx3 |
T |
A |
18: 90,555,210 (GRCm39) |
V309D |
possibly damaging |
Het |
| Trim30b |
C |
G |
7: 104,006,506 (GRCm39) |
V117L |
possibly damaging |
Het |
| Tsen2 |
C |
A |
6: 115,536,989 (GRCm39) |
H248Q |
probably benign |
Het |
| Ttn |
T |
C |
2: 76,567,412 (GRCm39) |
Y19500C |
probably damaging |
Het |
| Tubgcp2 |
A |
G |
7: 139,613,696 (GRCm39) |
|
probably benign |
Het |
| Vwf |
A |
C |
6: 125,585,254 (GRCm39) |
D712A |
possibly damaging |
Het |
| Wfdc2 |
A |
G |
2: 164,407,828 (GRCm39) |
K166E |
probably damaging |
Het |
| Xrcc2 |
T |
C |
5: 25,897,292 (GRCm39) |
D219G |
probably benign |
Het |
| Zc3h6 |
C |
T |
2: 128,858,989 (GRCm39) |
P1007S |
probably benign |
Het |
| Zdhhc17 |
A |
T |
10: 110,784,050 (GRCm39) |
|
probably null |
Het |
| Zfp369 |
T |
A |
13: 65,439,979 (GRCm39) |
I221N |
probably damaging |
Het |
| Zfp655 |
A |
T |
5: 145,181,411 (GRCm39) |
N423I |
probably damaging |
Het |
|
| Other mutations in Nckap5 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00833:Nckap5
|
APN |
1 |
125,954,889 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00956:Nckap5
|
APN |
1 |
125,952,755 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01414:Nckap5
|
APN |
1 |
126,456,450 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01482:Nckap5
|
APN |
1 |
125,950,897 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01508:Nckap5
|
APN |
1 |
125,953,309 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02071:Nckap5
|
APN |
1 |
125,909,305 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02129:Nckap5
|
APN |
1 |
125,955,432 (GRCm39) |
nonsense |
probably null |
|
|
IGL02821:Nckap5
|
APN |
1 |
125,955,553 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03174:Nckap5
|
APN |
1 |
125,909,383 (GRCm39) |
missense |
probably damaging |
1.00 |
|
F5493:Nckap5
|
UTSW |
1 |
125,953,564 (GRCm39) |
missense |
probably benign |
|
|
G5030:Nckap5
|
UTSW |
1 |
125,953,591 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0033:Nckap5
|
UTSW |
1 |
125,867,979 (GRCm39) |
intron |
probably benign |
|
|
R0164:Nckap5
|
UTSW |
1 |
125,952,144 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R0164:Nckap5
|
UTSW |
1 |
125,952,144 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R0349:Nckap5
|
UTSW |
1 |
125,954,171 (GRCm39) |
missense |
probably benign |
|
|
R0482:Nckap5
|
UTSW |
1 |
125,954,102 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0508:Nckap5
|
UTSW |
1 |
125,909,121 (GRCm39) |
splice site |
probably null |
|
|
R0541:Nckap5
|
UTSW |
1 |
126,623,459 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R0609:Nckap5
|
UTSW |
1 |
125,955,025 (GRCm39) |
nonsense |
probably null |
|
|
R0701:Nckap5
|
UTSW |
1 |
125,953,094 (GRCm39) |
missense |
probably benign |
0.06 |
|
R0782:Nckap5
|
UTSW |
1 |
125,909,278 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1389:Nckap5
|
UTSW |
1 |
125,954,447 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1401:Nckap5
|
UTSW |
1 |
125,942,398 (GRCm39) |
splice site |
probably benign |
|
|
R1436:Nckap5
|
UTSW |
1 |
125,953,798 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R1506:Nckap5
|
UTSW |
1 |
125,953,650 (GRCm39) |
nonsense |
probably null |
|
|
R1942:Nckap5
|
UTSW |
1 |
125,952,039 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1968:Nckap5
|
UTSW |
1 |
125,942,367 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2055:Nckap5
|
UTSW |
1 |
125,954,635 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2105:Nckap5
|
UTSW |
1 |
125,954,255 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2214:Nckap5
|
UTSW |
1 |
125,953,487 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R2311:Nckap5
|
UTSW |
1 |
126,456,489 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2403:Nckap5
|
UTSW |
1 |
125,955,146 (GRCm39) |
missense |
probably benign |
0.18 |
|
R2430:Nckap5
|
UTSW |
1 |
125,842,494 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2914:Nckap5
|
UTSW |
1 |
125,954,274 (GRCm39) |
splice site |
probably null |
|
|
R3782:Nckap5
|
UTSW |
1 |
125,952,811 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4133:Nckap5
|
UTSW |
1 |
126,150,443 (GRCm39) |
missense |
probably benign |
0.13 |
|
R4249:Nckap5
|
UTSW |
1 |
125,955,376 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4448:Nckap5
|
UTSW |
1 |
125,953,463 (GRCm39) |
nonsense |
probably null |
|
|
R4456:Nckap5
|
UTSW |
1 |
125,842,472 (GRCm39) |
unclassified |
probably benign |
|
|
R4682:Nckap5
|
UTSW |
1 |
126,030,279 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4817:Nckap5
|
UTSW |
1 |
125,954,952 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R4907:Nckap5
|
UTSW |
1 |
125,953,889 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4908:Nckap5
|
UTSW |
1 |
125,955,324 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4924:Nckap5
|
UTSW |
1 |
125,954,765 (GRCm39) |
nonsense |
probably null |
|
|
R4926:Nckap5
|
UTSW |
1 |
126,456,378 (GRCm39) |
intron |
probably benign |
|
|
R5032:Nckap5
|
UTSW |
1 |
125,904,786 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R5133:Nckap5
|
UTSW |
1 |
125,961,697 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5197:Nckap5
|
UTSW |
1 |
126,150,410 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R5238:Nckap5
|
UTSW |
1 |
125,955,461 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5257:Nckap5
|
UTSW |
1 |
125,952,245 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5277:Nckap5
|
UTSW |
1 |
125,954,277 (GRCm39) |
nonsense |
probably null |
|
|
R5512:Nckap5
|
UTSW |
1 |
125,955,481 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R5700:Nckap5
|
UTSW |
1 |
125,904,662 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5789:Nckap5
|
UTSW |
1 |
125,955,439 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6029:Nckap5
|
UTSW |
1 |
125,953,523 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6249:Nckap5
|
UTSW |
1 |
125,952,667 (GRCm39) |
missense |
probably benign |
|
|
R6292:Nckap5
|
UTSW |
1 |
125,842,752 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6521:Nckap5
|
UTSW |
1 |
126,309,909 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6875:Nckap5
|
UTSW |
1 |
125,950,931 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7017:Nckap5
|
UTSW |
1 |
126,030,398 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7018:Nckap5
|
UTSW |
1 |
125,952,785 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7054:Nckap5
|
UTSW |
1 |
126,186,449 (GRCm39) |
splice site |
probably null |
|
|
R7204:Nckap5
|
UTSW |
1 |
125,954,104 (GRCm39) |
missense |
probably benign |
|
|
R7336:Nckap5
|
UTSW |
1 |
125,953,786 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7544:Nckap5
|
UTSW |
1 |
125,953,948 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7590:Nckap5
|
UTSW |
1 |
125,954,270 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7684:Nckap5
|
UTSW |
1 |
125,954,594 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7749:Nckap5
|
UTSW |
1 |
125,952,383 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7773:Nckap5
|
UTSW |
1 |
125,954,581 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7813:Nckap5
|
UTSW |
1 |
125,953,163 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7970:Nckap5
|
UTSW |
1 |
125,952,758 (GRCm39) |
nonsense |
probably null |
|
|
R7992:Nckap5
|
UTSW |
1 |
125,954,547 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8278:Nckap5
|
UTSW |
1 |
125,955,509 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8373:Nckap5
|
UTSW |
1 |
125,954,032 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8414:Nckap5
|
UTSW |
1 |
125,942,357 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8755:Nckap5
|
UTSW |
1 |
125,954,279 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8845:Nckap5
|
UTSW |
1 |
125,909,423 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R9016:Nckap5
|
UTSW |
1 |
126,623,491 (GRCm39) |
start codon destroyed |
probably null |
0.01 |
|
R9209:Nckap5
|
UTSW |
1 |
125,867,928 (GRCm39) |
missense |
unknown |
|
|
R9214:Nckap5
|
UTSW |
1 |
125,942,376 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9300:Nckap5
|
UTSW |
1 |
125,909,423 (GRCm39) |
nonsense |
probably null |
|
|
R9464:Nckap5
|
UTSW |
1 |
125,952,494 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9572:Nckap5
|
UTSW |
1 |
125,955,454 (GRCm39) |
missense |
probably benign |
0.41 |
|
R9721:Nckap5
|
UTSW |
1 |
125,955,017 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9748:Nckap5
|
UTSW |
1 |
125,953,939 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Nckap5
|
UTSW |
1 |
125,952,569 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
Z1176:Nckap5
|
UTSW |
1 |
126,456,418 (GRCm39) |
critical splice donor site |
probably null |
|
|
Z1177:Nckap5
|
UTSW |
1 |
126,150,396 (GRCm39) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CGACACTAGTCCCAGTTGAAGAAGC -3'
(R):5'- TCAATGGAAGGGTCCCCAAGCAAG -3'
Sequencing Primer
(F):5'- TCCCAGTTGAAGAAGCATCTG -3'
(R):5'- TAATCTGCCCAATGCTGGAAG -3'
|
| Posted On |
2014-04-13 |
Incidental Mutation