Incidental Mutation 'R1528:Cacna1i'
| ID |
166403 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Cacna1i
|
| Ensembl Gene |
ENSMUSG00000022416 |
| Gene Name |
calcium channel, voltage-dependent, alpha 1I subunit |
| Synonyms |
|
| MMRRC Submission |
039568-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1528 (G1)
|
| Quality Score |
223 |
|
Status
|
Not validated
|
| Chromosome |
15 |
| Chromosomal Location |
80171439-80282480 bp(+) (GRCm39) |
| Type of Mutation |
splice site (4 bp from exon) |
| DNA Base Change (assembly) |
A to G
at 80275975 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000125063
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000160424]
[ENSMUST00000162155]
|
| AlphaFold |
E9Q7P2 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000160175
|
| SMART Domains |
Protein: ENSMUSP00000123881
Gene: ENSMUSG00000022416
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
7 |
23 |
N/A |
INTRINSIC |
|
low complexity region
|
93 |
104 |
N/A |
INTRINSIC |
|
low complexity region
|
127 |
143 |
N/A |
INTRINSIC |
|
low complexity region
|
212 |
223 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000160175
|
| SMART Domains |
Protein: ENSMUSP00000123881
Gene: ENSMUSG00000022416
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
7 |
23 |
N/A |
INTRINSIC |
|
low complexity region
|
93 |
104 |
N/A |
INTRINSIC |
|
low complexity region
|
127 |
143 |
N/A |
INTRINSIC |
|
low complexity region
|
212 |
223 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000160424
|
| SMART Domains |
Protein: ENSMUSP00000125063
Gene: ENSMUSG00000022416
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
16 |
N/A |
INTRINSIC |
|
low complexity region
|
24 |
40 |
N/A |
INTRINSIC |
|
Pfam:Ion_trans
|
76 |
407 |
1.4e-79 |
PFAM |
|
low complexity region
|
464 |
482 |
N/A |
INTRINSIC |
|
low complexity region
|
531 |
554 |
N/A |
INTRINSIC |
|
Pfam:Ion_trans
|
597 |
830 |
7.4e-58 |
PFAM |
|
low complexity region
|
870 |
892 |
N/A |
INTRINSIC |
|
low complexity region
|
919 |
940 |
N/A |
INTRINSIC |
|
low complexity region
|
984 |
1015 |
N/A |
INTRINSIC |
|
low complexity region
|
1069 |
1080 |
N/A |
INTRINSIC |
|
Pfam:Ion_trans
|
1128 |
1401 |
7.8e-65 |
PFAM |
|
Pfam:Ion_trans
|
1445 |
1700 |
9.4e-58 |
PFAM |
|
Pfam:PKD_channel
|
1538 |
1694 |
1.4e-10 |
PFAM |
|
low complexity region
|
1718 |
1739 |
N/A |
INTRINSIC |
|
low complexity region
|
1744 |
1760 |
N/A |
INTRINSIC |
|
low complexity region
|
1837 |
1853 |
N/A |
INTRINSIC |
|
low complexity region
|
1922 |
1933 |
N/A |
INTRINSIC |
|
low complexity region
|
1990 |
2005 |
N/A |
INTRINSIC |
|
low complexity region
|
2041 |
2058 |
N/A |
INTRINSIC |
|
low complexity region
|
2087 |
2097 |
N/A |
INTRINSIC |
|
low complexity region
|
2103 |
2126 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000161863
|
| SMART Domains |
Protein: ENSMUSP00000124367
Gene: ENSMUSG00000022416
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
7 |
23 |
N/A |
INTRINSIC |
|
low complexity region
|
80 |
91 |
N/A |
INTRINSIC |
|
low complexity region
|
114 |
130 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000162025
|
| SMART Domains |
Protein: ENSMUSP00000125530
Gene: ENSMUSG00000022416
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
7 |
23 |
N/A |
INTRINSIC |
|
low complexity region
|
87 |
103 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000162155
|
| SMART Domains |
Protein: ENSMUSP00000125229
Gene: ENSMUSG00000022416
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
16 |
N/A |
INTRINSIC |
|
low complexity region
|
24 |
40 |
N/A |
INTRINSIC |
|
Pfam:Ion_trans
|
115 |
395 |
1.9e-66 |
PFAM |
|
low complexity region
|
464 |
482 |
N/A |
INTRINSIC |
|
low complexity region
|
531 |
554 |
N/A |
INTRINSIC |
|
Pfam:Ion_trans
|
632 |
819 |
2.4e-45 |
PFAM |
|
low complexity region
|
870 |
892 |
N/A |
INTRINSIC |
|
low complexity region
|
919 |
940 |
N/A |
INTRINSIC |
|
low complexity region
|
984 |
1015 |
N/A |
INTRINSIC |
|
low complexity region
|
1069 |
1080 |
N/A |
INTRINSIC |
|
Pfam:Ion_trans
|
1165 |
1389 |
6.2e-55 |
PFAM |
|
coiled coil region
|
1394 |
1426 |
N/A |
INTRINSIC |
|
Pfam:Ion_trans
|
1480 |
1688 |
1.9e-47 |
PFAM |
|
Pfam:PKD_channel
|
1538 |
1694 |
4.8e-10 |
PFAM |
|
low complexity region
|
1718 |
1739 |
N/A |
INTRINSIC |
|
low complexity region
|
1744 |
1760 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000162913
|
| SMART Domains |
Protein: ENSMUSP00000125617
Gene: ENSMUSG00000022416
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
7 |
23 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.4%
- 3x: 98.7%
- 10x: 97.3%
- 20x: 95.4%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes the pore-forming alpha subunit of a voltage gated calcium channel. The encoded protein is a member of a subfamily of calcium channels referred to as is a low voltage-activated, T-type, calcium channel. The channel encoded by this protein is characterized by a slower activation and inactivation compared to other T-type calcium channels. This protein may be involved in calcium signaling in neurons. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 83 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2610008E11Rik |
T |
A |
10: 78,903,530 (GRCm39) |
Q262L |
possibly damaging |
Het |
| Abcg4 |
T |
C |
9: 44,186,020 (GRCm39) |
Y617C |
probably damaging |
Het |
| Amph |
G |
A |
13: 19,326,198 (GRCm39) |
V643M |
probably damaging |
Het |
| Ano1 |
T |
G |
7: 144,149,303 (GRCm39) |
S853R |
probably damaging |
Het |
| Ap4e1 |
T |
A |
2: 126,853,743 (GRCm39) |
S60R |
possibly damaging |
Het |
| Atp4b |
C |
A |
8: 13,439,693 (GRCm39) |
K176N |
possibly damaging |
Het |
| Atxn2 |
A |
T |
5: 121,940,171 (GRCm39) |
D982V |
probably damaging |
Het |
| Atxn2 |
T |
C |
5: 121,951,593 (GRCm39) |
F646S |
probably damaging |
Het |
| Bcl2l13 |
T |
C |
6: 120,847,755 (GRCm39) |
C136R |
possibly damaging |
Het |
| Bltp1 |
C |
T |
3: 37,106,684 (GRCm39) |
H5005Y |
unknown |
Het |
| Ccdc122 |
T |
A |
14: 77,305,379 (GRCm39) |
V11D |
possibly damaging |
Het |
| Cdnf |
A |
G |
2: 3,522,078 (GRCm39) |
D90G |
probably damaging |
Het |
| Cep104 |
T |
G |
4: 154,078,965 (GRCm39) |
V323G |
probably benign |
Het |
| Chmp6 |
A |
G |
11: 119,807,541 (GRCm39) |
D128G |
probably benign |
Het |
| Clec18a |
A |
T |
8: 111,805,498 (GRCm39) |
M201K |
probably benign |
Het |
| Col11a1 |
A |
T |
3: 114,010,644 (GRCm39) |
|
probably benign |
Het |
| Col6a4 |
A |
T |
9: 105,952,419 (GRCm39) |
M493K |
probably damaging |
Het |
| Crygd |
A |
C |
1: 65,102,216 (GRCm39) |
|
probably null |
Het |
| Dennd1c |
T |
C |
17: 57,373,935 (GRCm39) |
T543A |
probably benign |
Het |
| Erbb4 |
A |
T |
1: 68,117,741 (GRCm39) |
C891* |
probably null |
Het |
| Ercc5 |
A |
T |
1: 44,217,401 (GRCm39) |
K915* |
probably null |
Het |
| Ercc6 |
A |
T |
14: 32,240,979 (GRCm39) |
N168Y |
probably damaging |
Het |
| Esrp2 |
G |
T |
8: 106,863,384 (GRCm39) |
P6T |
unknown |
Het |
| Exoc1 |
A |
G |
5: 76,697,411 (GRCm39) |
K396R |
possibly damaging |
Het |
| Fat3 |
T |
A |
9: 15,836,387 (GRCm39) |
Y4039F |
probably benign |
Het |
| Fcsk |
A |
T |
8: 111,609,873 (GRCm39) |
L1047Q |
probably damaging |
Het |
| Fgf7 |
T |
A |
2: 125,877,738 (GRCm39) |
M35K |
probably damaging |
Het |
| Fras1 |
G |
A |
5: 96,784,678 (GRCm39) |
G887D |
probably damaging |
Het |
| Gbp4 |
A |
T |
5: 105,269,658 (GRCm39) |
|
probably null |
Het |
| Homez |
A |
T |
14: 55,095,162 (GRCm39) |
M182K |
probably benign |
Het |
| Hrnr |
G |
A |
3: 93,230,101 (GRCm39) |
S113N |
possibly damaging |
Het |
| Ifit3b |
T |
G |
19: 34,589,072 (GRCm39) |
S83A |
probably benign |
Het |
| Ildr2 |
A |
G |
1: 166,098,064 (GRCm39) |
|
probably null |
Het |
| Klhdc1 |
A |
T |
12: 69,309,972 (GRCm39) |
R291S |
probably benign |
Het |
| Krt77 |
T |
A |
15: 101,769,523 (GRCm39) |
I413F |
probably damaging |
Het |
| Lipn |
A |
G |
19: 34,046,070 (GRCm39) |
I14M |
probably damaging |
Het |
| Macf1 |
T |
G |
4: 123,369,807 (GRCm39) |
R86S |
probably benign |
Het |
| Mroh8 |
C |
A |
2: 157,071,975 (GRCm39) |
G510V |
probably damaging |
Het |
| Mycbp2 |
A |
T |
14: 103,470,033 (GRCm39) |
D1255E |
possibly damaging |
Het |
| Nckap5 |
C |
T |
1: 125,952,659 (GRCm39) |
V1234I |
possibly damaging |
Het |
| Nlrp9c |
T |
C |
7: 26,081,723 (GRCm39) |
K668E |
probably damaging |
Het |
| Nod2 |
T |
C |
8: 89,391,217 (GRCm39) |
M508T |
possibly damaging |
Het |
| Npffr1 |
A |
G |
10: 61,450,016 (GRCm39) |
M97V |
possibly damaging |
Het |
| Nsd3 |
G |
A |
8: 26,188,795 (GRCm39) |
V43M |
probably damaging |
Het |
| Nubp2 |
A |
G |
17: 25,103,388 (GRCm39) |
V163A |
probably damaging |
Het |
| Oas1e |
A |
T |
5: 120,926,054 (GRCm39) |
F338Y |
probably damaging |
Het |
| Oat |
C |
A |
7: 132,165,998 (GRCm39) |
G196C |
probably damaging |
Het |
| Or4a69 |
C |
T |
2: 89,312,897 (GRCm39) |
G194D |
probably damaging |
Het |
| Or52e8b |
A |
T |
7: 104,673,971 (GRCm39) |
L72Q |
probably damaging |
Het |
| Or7a41 |
T |
C |
10: 78,871,398 (GRCm39) |
L256P |
probably damaging |
Het |
| P2ry13 |
T |
C |
3: 59,117,710 (GRCm39) |
T23A |
probably benign |
Het |
| Phf8-ps |
A |
G |
17: 33,286,215 (GRCm39) |
S196P |
probably damaging |
Het |
| Pja2 |
C |
A |
17: 64,616,217 (GRCm39) |
S226I |
possibly damaging |
Het |
| Pkhd1l1 |
T |
C |
15: 44,390,120 (GRCm39) |
V1412A |
probably damaging |
Het |
| Plekhs1 |
T |
C |
19: 56,468,427 (GRCm39) |
S332P |
probably damaging |
Het |
| Polr3e |
T |
A |
7: 120,539,820 (GRCm39) |
N522K |
probably damaging |
Het |
| Prdm10 |
A |
G |
9: 31,268,582 (GRCm39) |
T844A |
probably damaging |
Het |
| Ripk1 |
C |
T |
13: 34,212,130 (GRCm39) |
P480L |
probably benign |
Het |
| Rnf139 |
T |
C |
15: 58,771,064 (GRCm39) |
V363A |
probably damaging |
Het |
| Rnf19a |
A |
T |
15: 36,265,801 (GRCm39) |
S99T |
possibly damaging |
Het |
| Rnf224 |
G |
A |
2: 25,126,110 (GRCm39) |
T81I |
probably benign |
Het |
| Rpgrip1 |
T |
C |
14: 52,349,681 (GRCm39) |
L23S |
probably benign |
Het |
| Setd5 |
T |
A |
6: 113,098,699 (GRCm39) |
F758L |
probably damaging |
Het |
| Smlr1 |
C |
A |
10: 25,411,976 (GRCm39) |
V4L |
possibly damaging |
Het |
| Snx1 |
T |
C |
9: 66,016,825 (GRCm39) |
D34G |
probably damaging |
Het |
| Spaca5 |
A |
T |
X: 20,942,892 (GRCm39) |
T92S |
probably benign |
Het |
| Speer4f2 |
A |
G |
5: 17,581,540 (GRCm39) |
T161A |
|
Het |
| Swi5 |
C |
A |
2: 32,170,716 (GRCm39) |
|
probably null |
Het |
| Syne2 |
T |
A |
12: 76,012,874 (GRCm39) |
D2689E |
probably benign |
Het |
| Tcof1 |
T |
A |
18: 60,948,071 (GRCm39) |
K1299* |
probably null |
Het |
| Tmprss11e |
G |
A |
5: 86,872,069 (GRCm39) |
T49I |
probably damaging |
Het |
| Tmx3 |
T |
A |
18: 90,555,210 (GRCm39) |
V309D |
possibly damaging |
Het |
| Trim30b |
C |
G |
7: 104,006,506 (GRCm39) |
V117L |
possibly damaging |
Het |
| Tsen2 |
C |
A |
6: 115,536,989 (GRCm39) |
H248Q |
probably benign |
Het |
| Ttn |
T |
C |
2: 76,567,412 (GRCm39) |
Y19500C |
probably damaging |
Het |
| Tubgcp2 |
A |
G |
7: 139,613,696 (GRCm39) |
|
probably benign |
Het |
| Vwf |
A |
C |
6: 125,585,254 (GRCm39) |
D712A |
possibly damaging |
Het |
| Wfdc2 |
A |
G |
2: 164,407,828 (GRCm39) |
K166E |
probably damaging |
Het |
| Xrcc2 |
T |
C |
5: 25,897,292 (GRCm39) |
D219G |
probably benign |
Het |
| Zc3h6 |
C |
T |
2: 128,858,989 (GRCm39) |
P1007S |
probably benign |
Het |
| Zdhhc17 |
A |
T |
10: 110,784,050 (GRCm39) |
|
probably null |
Het |
| Zfp369 |
T |
A |
13: 65,439,979 (GRCm39) |
I221N |
probably damaging |
Het |
| Zfp655 |
A |
T |
5: 145,181,411 (GRCm39) |
N423I |
probably damaging |
Het |
|
| Other mutations in Cacna1i |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00421:Cacna1i
|
APN |
15 |
80,266,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00976:Cacna1i
|
APN |
15 |
80,239,846 (GRCm39) |
missense |
probably benign |
|
|
IGL01338:Cacna1i
|
APN |
15 |
80,232,581 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01589:Cacna1i
|
APN |
15 |
80,271,960 (GRCm39) |
splice site |
probably benign |
|
|
IGL01669:Cacna1i
|
APN |
15 |
80,275,958 (GRCm39) |
missense |
probably benign |
|
|
IGL01807:Cacna1i
|
APN |
15 |
80,258,348 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01911:Cacna1i
|
APN |
15 |
80,275,933 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL01973:Cacna1i
|
APN |
15 |
80,266,234 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02205:Cacna1i
|
APN |
15 |
80,257,152 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL02519:Cacna1i
|
APN |
15 |
80,246,075 (GRCm39) |
nonsense |
probably null |
|
|
IGL02648:Cacna1i
|
APN |
15 |
80,182,839 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL03033:Cacna1i
|
APN |
15 |
80,246,440 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL03214:Cacna1i
|
APN |
15 |
80,239,917 (GRCm39) |
missense |
probably benign |
0.30 |
|
R0067:Cacna1i
|
UTSW |
15 |
80,265,373 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0067:Cacna1i
|
UTSW |
15 |
80,265,373 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0295:Cacna1i
|
UTSW |
15 |
80,240,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0345:Cacna1i
|
UTSW |
15 |
80,256,663 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0415:Cacna1i
|
UTSW |
15 |
80,253,031 (GRCm39) |
splice site |
probably benign |
|
|
R0637:Cacna1i
|
UTSW |
15 |
80,256,855 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0638:Cacna1i
|
UTSW |
15 |
80,265,281 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0840:Cacna1i
|
UTSW |
15 |
80,243,150 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R1463:Cacna1i
|
UTSW |
15 |
80,263,255 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R1563:Cacna1i
|
UTSW |
15 |
80,205,389 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1563:Cacna1i
|
UTSW |
15 |
80,274,056 (GRCm39) |
splice site |
probably benign |
|
|
R1573:Cacna1i
|
UTSW |
15 |
80,277,869 (GRCm39) |
splice site |
probably null |
|
|
R1654:Cacna1i
|
UTSW |
15 |
80,273,411 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1754:Cacna1i
|
UTSW |
15 |
80,255,730 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1794:Cacna1i
|
UTSW |
15 |
80,273,323 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1824:Cacna1i
|
UTSW |
15 |
80,260,990 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R1863:Cacna1i
|
UTSW |
15 |
80,243,132 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1885:Cacna1i
|
UTSW |
15 |
80,243,145 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1886:Cacna1i
|
UTSW |
15 |
80,243,145 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1899:Cacna1i
|
UTSW |
15 |
80,275,843 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R1907:Cacna1i
|
UTSW |
15 |
80,259,465 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1943:Cacna1i
|
UTSW |
15 |
80,279,245 (GRCm39) |
missense |
probably benign |
|
|
R2162:Cacna1i
|
UTSW |
15 |
80,240,388 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2888:Cacna1i
|
UTSW |
15 |
80,258,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3701:Cacna1i
|
UTSW |
15 |
80,265,272 (GRCm39) |
splice site |
probably benign |
|
|
R3702:Cacna1i
|
UTSW |
15 |
80,265,272 (GRCm39) |
splice site |
probably benign |
|
|
R3832:Cacna1i
|
UTSW |
15 |
80,240,388 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4852:Cacna1i
|
UTSW |
15 |
80,272,680 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4857:Cacna1i
|
UTSW |
15 |
80,253,863 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4950:Cacna1i
|
UTSW |
15 |
80,252,872 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4980:Cacna1i
|
UTSW |
15 |
80,232,650 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5217:Cacna1i
|
UTSW |
15 |
80,275,041 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5437:Cacna1i
|
UTSW |
15 |
80,255,730 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5519:Cacna1i
|
UTSW |
15 |
80,255,700 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5642:Cacna1i
|
UTSW |
15 |
80,279,279 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R6217:Cacna1i
|
UTSW |
15 |
80,273,333 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6225:Cacna1i
|
UTSW |
15 |
80,205,427 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6251:Cacna1i
|
UTSW |
15 |
80,220,883 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6463:Cacna1i
|
UTSW |
15 |
80,239,959 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6490:Cacna1i
|
UTSW |
15 |
80,262,448 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6613:Cacna1i
|
UTSW |
15 |
80,205,460 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6884:Cacna1i
|
UTSW |
15 |
80,259,010 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6904:Cacna1i
|
UTSW |
15 |
80,259,002 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7017:Cacna1i
|
UTSW |
15 |
80,264,671 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7155:Cacna1i
|
UTSW |
15 |
80,279,439 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7274:Cacna1i
|
UTSW |
15 |
80,261,023 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7323:Cacna1i
|
UTSW |
15 |
80,275,854 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R7335:Cacna1i
|
UTSW |
15 |
80,259,776 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7571:Cacna1i
|
UTSW |
15 |
80,259,537 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7768:Cacna1i
|
UTSW |
15 |
80,265,389 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7820:Cacna1i
|
UTSW |
15 |
80,256,573 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7987:Cacna1i
|
UTSW |
15 |
80,204,553 (GRCm39) |
splice site |
probably null |
|
|
R8150:Cacna1i
|
UTSW |
15 |
80,259,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8206:Cacna1i
|
UTSW |
15 |
80,274,016 (GRCm39) |
splice site |
probably null |
|
|
R8270:Cacna1i
|
UTSW |
15 |
80,257,835 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8382:Cacna1i
|
UTSW |
15 |
80,261,017 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8501:Cacna1i
|
UTSW |
15 |
80,266,247 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8518:Cacna1i
|
UTSW |
15 |
80,243,095 (GRCm39) |
nonsense |
probably null |
|
|
R8552:Cacna1i
|
UTSW |
15 |
80,204,598 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R8679:Cacna1i
|
UTSW |
15 |
80,260,011 (GRCm39) |
intron |
probably benign |
|
|
R8696:Cacna1i
|
UTSW |
15 |
80,266,175 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8887:Cacna1i
|
UTSW |
15 |
80,258,894 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9274:Cacna1i
|
UTSW |
15 |
80,254,354 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9379:Cacna1i
|
UTSW |
15 |
80,259,495 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9508:Cacna1i
|
UTSW |
15 |
80,279,372 (GRCm39) |
missense |
probably benign |
0.06 |
|
R9518:Cacna1i
|
UTSW |
15 |
80,271,978 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9674:Cacna1i
|
UTSW |
15 |
80,264,629 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9747:Cacna1i
|
UTSW |
15 |
80,246,318 (GRCm39) |
missense |
probably benign |
0.11 |
|
R9769:Cacna1i
|
UTSW |
15 |
80,253,793 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0022:Cacna1i
|
UTSW |
15 |
80,246,163 (GRCm39) |
missense |
probably damaging |
0.99 |
|
X0024:Cacna1i
|
UTSW |
15 |
80,246,340 (GRCm39) |
missense |
probably benign |
0.03 |
|
X0058:Cacna1i
|
UTSW |
15 |
80,263,303 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Cacna1i
|
UTSW |
15 |
80,273,584 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
Z1177:Cacna1i
|
UTSW |
15 |
80,265,380 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGTGCTCACCACACTGAGTTAGCC -3'
(R):5'- TCTCCGATTAGACTCCACCCAAAGG -3'
Sequencing Primer
(F):5'- ggtggaggaggtaagagaaag -3'
(R):5'- TCTGCTTGACACTAAGAGCTG -3'
|
| Posted On |
2014-04-13 |
Incidental Mutation