Incidental Mutation 'R0164:Nckap5'
| ID |
24017 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Nckap5
|
| Ensembl Gene |
ENSMUSG00000049690 |
| Gene Name |
NCK-associated protein 5 |
| Synonyms |
E030049G20Rik, LOC380609, D130011D22Rik |
| MMRRC Submission |
038440-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R0164 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
(trace)
|
| Chromosome |
1 |
| Chromosomal Location |
125913620-126830799 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 126024407 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glutamic Acid
at position 1405
(D1405E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000062229
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000057846]
[ENSMUST00000094609]
[ENSMUST00000094610]
[ENSMUST00000112583]
[ENSMUST00000161954]
[ENSMUST00000162877]
|
| AlphaFold |
E9QAE1 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000057846
AA Change: D1405E
PolyPhen 2
Score 0.837 (Sensitivity: 0.84; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000062229
Gene: ENSMUSG00000049690
AA Change: D1405E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
25 |
N/A |
INTRINSIC |
|
coiled coil region
|
108 |
186 |
N/A |
INTRINSIC |
|
low complexity region
|
321 |
332 |
N/A |
INTRINSIC |
|
low complexity region
|
755 |
771 |
N/A |
INTRINSIC |
|
low complexity region
|
950 |
971 |
N/A |
INTRINSIC |
|
low complexity region
|
1070 |
1085 |
N/A |
INTRINSIC |
|
low complexity region
|
1181 |
1200 |
N/A |
INTRINSIC |
|
Pfam:NCKAP5
|
1298 |
1602 |
1.8e-120 |
PFAM |
|
low complexity region
|
1728 |
1742 |
N/A |
INTRINSIC |
|
low complexity region
|
1757 |
1771 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000094609
|
| SMART Domains |
Protein: ENSMUSP00000092192
Gene: ENSMUSG00000049690
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
70 |
93 |
N/A |
INTRINSIC |
|
Pfam:NCKAP5
|
113 |
364 |
3.6e-36 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000094610
|
| SMART Domains |
Protein: ENSMUSP00000092193
Gene: ENSMUSG00000049690
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:NCKAP5
|
1 |
101 |
8.8e-42 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000112583
AA Change: D1537E
PolyPhen 2
Score 0.417 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000108202
Gene: ENSMUSG00000049690
AA Change: D1537E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
70 |
93 |
N/A |
INTRINSIC |
|
coiled coil region
|
176 |
254 |
N/A |
INTRINSIC |
|
low complexity region
|
301 |
324 |
N/A |
INTRINSIC |
|
low complexity region
|
453 |
464 |
N/A |
INTRINSIC |
|
low complexity region
|
887 |
903 |
N/A |
INTRINSIC |
|
low complexity region
|
1082 |
1103 |
N/A |
INTRINSIC |
|
low complexity region
|
1202 |
1217 |
N/A |
INTRINSIC |
|
low complexity region
|
1313 |
1332 |
N/A |
INTRINSIC |
|
Pfam:NCKAP5
|
1431 |
1733 |
5.3e-119 |
PFAM |
|
low complexity region
|
1860 |
1874 |
N/A |
INTRINSIC |
|
low complexity region
|
1889 |
1903 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000159934
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000161954
AA Change: D1469E
PolyPhen 2
Score 0.417 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000125624
Gene: ENSMUSG00000049690
AA Change: D1469E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
25 |
N/A |
INTRINSIC |
|
coiled coil region
|
108 |
186 |
N/A |
INTRINSIC |
|
low complexity region
|
233 |
256 |
N/A |
INTRINSIC |
|
low complexity region
|
385 |
396 |
N/A |
INTRINSIC |
|
low complexity region
|
819 |
835 |
N/A |
INTRINSIC |
|
low complexity region
|
1014 |
1035 |
N/A |
INTRINSIC |
|
low complexity region
|
1134 |
1149 |
N/A |
INTRINSIC |
|
low complexity region
|
1245 |
1264 |
N/A |
INTRINSIC |
|
Pfam:NCKAP5
|
1362 |
1666 |
2.1e-120 |
PFAM |
|
low complexity region
|
1792 |
1806 |
N/A |
INTRINSIC |
|
low complexity region
|
1821 |
1835 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000162877
|
| SMART Domains |
Protein: ENSMUSP00000124748
Gene: ENSMUSG00000049690
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:NCKAP5
|
9 |
296 |
6e-36 |
PFAM |
|
| Meta Mutation Damage Score |
0.1795 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.7%
- 20x: 94.0%
|
| Validation Efficiency |
98% (85/87) |
| Allele List at MGI |
All alleles(1) : Gene trapped(1) |
| Other mutations in this stock |
Total: 89 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2010315B03Rik |
T |
C |
9: 124,295,159 (GRCm38) |
|
probably benign |
Het |
| 4732465J04Rik |
GATCTATCTATCTATCTATCTATCTATCTATCTATCTATC |
GATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATC |
10: 95,794,578 (GRCm38) |
|
probably null |
Het |
| 4930522L14Rik |
T |
C |
5: 109,736,847 (GRCm38) |
K382E |
probably damaging |
Het |
| Adck1 |
A |
G |
12: 88,455,510 (GRCm38) |
E297G |
probably damaging |
Het |
| Ahrr |
G |
A |
13: 74,283,024 (GRCm38) |
|
probably benign |
Het |
| Aldh3a2 |
C |
T |
11: 61,248,888 (GRCm38) |
V473I |
probably benign |
Het |
| Arfgef3 |
A |
T |
10: 18,647,915 (GRCm38) |
I369K |
possibly damaging |
Het |
| Atl2 |
A |
G |
17: 79,853,831 (GRCm38) |
|
probably benign |
Het |
| Atp1b3 |
T |
C |
9: 96,338,709 (GRCm38) |
I178V |
possibly damaging |
Het |
| Axdnd1 |
T |
C |
1: 156,378,386 (GRCm38) |
E520G |
possibly damaging |
Het |
| Bahcc1 |
A |
T |
11: 120,285,074 (GRCm38) |
|
probably benign |
Het |
| BB019430 |
A |
T |
10: 58,704,271 (GRCm38) |
|
noncoding transcript |
Het |
| BC028528 |
A |
T |
3: 95,887,334 (GRCm38) |
|
probably benign |
Het |
| Btbd1 |
T |
A |
7: 81,801,003 (GRCm38) |
Q343L |
probably benign |
Het |
| Catsper1 |
A |
G |
19: 5,339,475 (GRCm38) |
T473A |
possibly damaging |
Het |
| Ccn4 |
T |
C |
15: 66,919,210 (GRCm38) |
L287P |
probably damaging |
Het |
| Chmp6 |
G |
A |
11: 119,915,523 (GRCm38) |
|
probably null |
Het |
| Cstdc7 |
T |
A |
18: 42,173,543 (GRCm38) |
D58E |
probably damaging |
Het |
| D130040H23Rik |
T |
C |
8: 69,302,543 (GRCm38) |
V200A |
possibly damaging |
Het |
| D830013O20Rik |
C |
T |
12: 73,364,331 (GRCm38) |
|
noncoding transcript |
Het |
| Dcaf1 |
T |
A |
9: 106,844,145 (GRCm38) |
S379T |
possibly damaging |
Het |
| Dcaf4 |
G |
A |
12: 83,535,988 (GRCm38) |
|
probably benign |
Het |
| Dhx58 |
T |
C |
11: 100,695,324 (GRCm38) |
I624V |
probably benign |
Het |
| Disp3 |
T |
C |
4: 148,254,251 (GRCm38) |
E821G |
probably damaging |
Het |
| Dlc1 |
T |
A |
8: 36,599,440 (GRCm38) |
E464V |
probably damaging |
Het |
| Dnah10 |
G |
A |
5: 124,783,834 (GRCm38) |
V2151I |
probably damaging |
Het |
| Dnah6 |
C |
T |
6: 73,188,535 (GRCm38) |
|
probably benign |
Het |
| Dnah8 |
G |
A |
17: 30,748,665 (GRCm38) |
G2617D |
probably benign |
Het |
| Dnah9 |
C |
A |
11: 65,918,804 (GRCm38) |
E872* |
probably null |
Het |
| Dock9 |
T |
C |
14: 121,597,665 (GRCm38) |
Y99C |
probably damaging |
Het |
| Dpy19l3 |
T |
A |
7: 35,716,646 (GRCm38) |
I310F |
probably damaging |
Het |
| Fggy |
A |
T |
4: 95,837,654 (GRCm38) |
I137F |
probably damaging |
Het |
| Gli2 |
A |
G |
1: 118,890,283 (GRCm38) |
|
probably benign |
Het |
| Gm14421 |
A |
T |
2: 177,056,722 (GRCm38) |
|
noncoding transcript |
Het |
| Grin2a |
A |
G |
16: 9,994,821 (GRCm38) |
|
probably null |
Het |
| Grin2b |
A |
G |
6: 135,778,648 (GRCm38) |
|
probably benign |
Het |
| Incenp |
A |
G |
19: 9,894,879 (GRCm38) |
S72P |
probably benign |
Het |
| Ipo11 |
A |
G |
13: 106,910,194 (GRCm38) |
|
probably benign |
Het |
| Klc3 |
T |
A |
7: 19,394,926 (GRCm38) |
N469Y |
possibly damaging |
Het |
| Lrrc42 |
A |
G |
4: 107,247,505 (GRCm38) |
S88P |
probably benign |
Het |
| Lrrc49 |
G |
A |
9: 60,680,600 (GRCm38) |
T93I |
probably benign |
Het |
| Ltn1 |
G |
A |
16: 87,405,519 (GRCm38) |
|
probably benign |
Het |
| Mlycd |
A |
T |
8: 119,407,641 (GRCm38) |
Q294L |
probably damaging |
Het |
| Mmrn1 |
T |
A |
6: 60,975,815 (GRCm38) |
|
probably benign |
Het |
| Mrpl22 |
T |
A |
11: 58,171,821 (GRCm38) |
I19N |
probably benign |
Het |
| Msh3 |
T |
A |
13: 92,349,209 (GRCm38) |
K202N |
probably damaging |
Het |
| N4bp2 |
T |
C |
5: 65,803,573 (GRCm38) |
|
probably benign |
Het |
| Ncam1 |
C |
T |
9: 49,568,409 (GRCm38) |
D90N |
probably damaging |
Het |
| Ncoa2 |
A |
G |
1: 13,186,731 (GRCm38) |
|
probably null |
Het |
| Ncoa6 |
TGC |
TGCGC |
2: 155,408,291 (GRCm38) |
|
probably null |
Het |
| Nlrp1b |
A |
T |
11: 71,164,099 (GRCm38) |
W844R |
probably damaging |
Het |
| Nmnat1 |
G |
T |
4: 149,469,150 (GRCm38) |
N168K |
possibly damaging |
Het |
| Or5b96 |
A |
G |
19: 12,890,445 (GRCm38) |
L44P |
probably damaging |
Het |
| Ost4 |
T |
C |
5: 30,907,459 (GRCm38) |
H26R |
probably damaging |
Het |
| Otog |
G |
A |
7: 46,304,231 (GRCm38) |
V2638M |
probably damaging |
Het |
| Otogl |
A |
T |
10: 107,874,530 (GRCm38) |
I566N |
probably damaging |
Het |
| Pcyt1a |
T |
C |
16: 32,470,186 (GRCm38) |
S282P |
probably damaging |
Het |
| Prkcg |
G |
A |
7: 3,329,119 (GRCm38) |
E581K |
probably damaging |
Het |
| Ralgps2 |
A |
G |
1: 156,887,089 (GRCm38) |
|
probably null |
Het |
| Rnf157 |
A |
G |
11: 116,354,810 (GRCm38) |
|
probably benign |
Het |
| Scmh1 |
T |
C |
4: 120,529,865 (GRCm38) |
|
probably benign |
Het |
| Sgo2b |
T |
C |
8: 63,938,383 (GRCm38) |
H150R |
possibly damaging |
Het |
| Sh2b3 |
T |
G |
5: 121,829,037 (GRCm38) |
T5P |
probably damaging |
Het |
| Skint6 |
A |
T |
4: 112,991,236 (GRCm38) |
|
probably benign |
Het |
| Slfn10-ps |
T |
C |
11: 83,035,302 (GRCm38) |
|
noncoding transcript |
Het |
| Sspo |
T |
A |
6: 48,494,194 (GRCm38) |
|
probably benign |
Het |
| Tcp1 |
T |
A |
17: 12,922,747 (GRCm38) |
|
probably benign |
Het |
| Tdp2 |
A |
G |
13: 24,838,239 (GRCm38) |
M214V |
probably damaging |
Het |
| Tenm4 |
T |
G |
7: 96,729,340 (GRCm38) |
|
probably benign |
Het |
| Tmem144 |
G |
A |
3: 79,839,273 (GRCm38) |
|
probably benign |
Het |
| Tmem204 |
A |
G |
17: 25,058,350 (GRCm38) |
I187T |
probably damaging |
Het |
| Tmem208 |
T |
G |
8: 105,334,694 (GRCm38) |
D117E |
probably benign |
Het |
| Tnks1bp1 |
C |
T |
2: 85,059,221 (GRCm38) |
P631S |
possibly damaging |
Het |
| Tomm70a |
T |
C |
16: 57,147,821 (GRCm38) |
V517A |
probably damaging |
Het |
| Ttc7 |
T |
C |
17: 87,379,895 (GRCm38) |
V801A |
probably damaging |
Het |
| Txndc5 |
A |
T |
13: 38,507,953 (GRCm38) |
C146S |
probably damaging |
Het |
| Ubac2 |
A |
G |
14: 122,008,917 (GRCm38) |
|
probably benign |
Het |
| Ube4b |
G |
T |
4: 149,360,324 (GRCm38) |
T493K |
probably damaging |
Het |
| Ufl1 |
A |
T |
4: 25,256,008 (GRCm38) |
Y504N |
probably benign |
Het |
| Ugt1a6a |
T |
C |
1: 88,139,270 (GRCm38) |
V266A |
possibly damaging |
Het |
| Ugt1a6b |
T |
A |
1: 88,107,467 (GRCm38) |
C176S |
probably damaging |
Het |
| Ulk3 |
T |
A |
9: 57,590,686 (GRCm38) |
I90N |
probably damaging |
Het |
| Unc13c |
T |
C |
9: 73,694,892 (GRCm38) |
I1357M |
probably benign |
Het |
| Vmn1r28 |
G |
A |
6: 58,265,717 (GRCm38) |
A182T |
probably benign |
Het |
| Vmn2r114 |
A |
G |
17: 23,309,826 (GRCm38) |
|
probably null |
Het |
| Vmn2r91 |
A |
C |
17: 18,106,137 (GRCm38) |
N228T |
probably benign |
Het |
| Wdr43 |
T |
G |
17: 71,631,997 (GRCm38) |
|
probably benign |
Het |
| Zbtb6 |
G |
T |
2: 37,429,588 (GRCm38) |
Y109* |
probably null |
Het |
| Zfp980 |
A |
G |
4: 145,701,997 (GRCm38) |
D432G |
probably benign |
Het |
|
| Other mutations in Nckap5 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00833:Nckap5
|
APN |
1 |
126,027,152 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL00956:Nckap5
|
APN |
1 |
126,025,018 (GRCm38) |
missense |
probably damaging |
0.98 |
|
IGL01414:Nckap5
|
APN |
1 |
126,528,713 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01482:Nckap5
|
APN |
1 |
126,023,160 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01508:Nckap5
|
APN |
1 |
126,025,572 (GRCm38) |
missense |
probably damaging |
0.96 |
|
IGL02071:Nckap5
|
APN |
1 |
125,981,568 (GRCm38) |
missense |
probably damaging |
0.97 |
|
IGL02129:Nckap5
|
APN |
1 |
126,027,695 (GRCm38) |
nonsense |
probably null |
|
|
IGL02821:Nckap5
|
APN |
1 |
126,027,816 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03174:Nckap5
|
APN |
1 |
125,981,646 (GRCm38) |
missense |
probably damaging |
1.00 |
|
F5493:Nckap5
|
UTSW |
1 |
126,025,827 (GRCm38) |
missense |
probably benign |
|
|
G5030:Nckap5
|
UTSW |
1 |
126,025,854 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R0033:Nckap5
|
UTSW |
1 |
125,940,242 (GRCm38) |
intron |
probably benign |
|
|
R0164:Nckap5
|
UTSW |
1 |
126,024,407 (GRCm38) |
missense |
possibly damaging |
0.84 |
|
R0349:Nckap5
|
UTSW |
1 |
126,026,434 (GRCm38) |
missense |
probably benign |
|
|
R0482:Nckap5
|
UTSW |
1 |
126,026,365 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R0508:Nckap5
|
UTSW |
1 |
125,981,384 (GRCm38) |
splice site |
probably null |
|
|
R0541:Nckap5
|
UTSW |
1 |
126,695,722 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R0609:Nckap5
|
UTSW |
1 |
126,027,288 (GRCm38) |
nonsense |
probably null |
|
|
R0701:Nckap5
|
UTSW |
1 |
126,025,357 (GRCm38) |
missense |
probably benign |
0.06 |
|
R0782:Nckap5
|
UTSW |
1 |
125,981,541 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1389:Nckap5
|
UTSW |
1 |
126,026,710 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R1401:Nckap5
|
UTSW |
1 |
126,014,661 (GRCm38) |
splice site |
probably benign |
|
|
R1436:Nckap5
|
UTSW |
1 |
126,026,061 (GRCm38) |
missense |
possibly damaging |
0.96 |
|
R1506:Nckap5
|
UTSW |
1 |
126,025,913 (GRCm38) |
nonsense |
probably null |
|
|
R1528:Nckap5
|
UTSW |
1 |
126,024,922 (GRCm38) |
missense |
possibly damaging |
0.68 |
|
R1942:Nckap5
|
UTSW |
1 |
126,024,302 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1968:Nckap5
|
UTSW |
1 |
126,014,630 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R2055:Nckap5
|
UTSW |
1 |
126,026,898 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2105:Nckap5
|
UTSW |
1 |
126,026,518 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2214:Nckap5
|
UTSW |
1 |
126,025,750 (GRCm38) |
missense |
possibly damaging |
0.77 |
|
R2311:Nckap5
|
UTSW |
1 |
126,528,752 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R2403:Nckap5
|
UTSW |
1 |
126,027,409 (GRCm38) |
missense |
probably benign |
0.18 |
|
R2430:Nckap5
|
UTSW |
1 |
125,914,757 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R2914:Nckap5
|
UTSW |
1 |
126,026,537 (GRCm38) |
splice site |
probably null |
|
|
R3782:Nckap5
|
UTSW |
1 |
126,025,074 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R4133:Nckap5
|
UTSW |
1 |
126,222,706 (GRCm38) |
missense |
probably benign |
0.13 |
|
R4249:Nckap5
|
UTSW |
1 |
126,027,639 (GRCm38) |
missense |
probably benign |
0.01 |
|
R4448:Nckap5
|
UTSW |
1 |
126,025,726 (GRCm38) |
nonsense |
probably null |
|
|
R4456:Nckap5
|
UTSW |
1 |
125,914,735 (GRCm38) |
unclassified |
probably benign |
|
|
R4682:Nckap5
|
UTSW |
1 |
126,102,542 (GRCm38) |
critical splice donor site |
probably null |
|
|
R4817:Nckap5
|
UTSW |
1 |
126,027,215 (GRCm38) |
missense |
possibly damaging |
0.68 |
|
R4907:Nckap5
|
UTSW |
1 |
126,026,152 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R4908:Nckap5
|
UTSW |
1 |
126,027,587 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4924:Nckap5
|
UTSW |
1 |
126,027,028 (GRCm38) |
nonsense |
probably null |
|
|
R4926:Nckap5
|
UTSW |
1 |
126,528,641 (GRCm38) |
intron |
probably benign |
|
|
R5032:Nckap5
|
UTSW |
1 |
125,977,049 (GRCm38) |
missense |
possibly damaging |
0.62 |
|
R5133:Nckap5
|
UTSW |
1 |
126,033,960 (GRCm38) |
missense |
probably benign |
0.01 |
|
R5197:Nckap5
|
UTSW |
1 |
126,222,673 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
R5238:Nckap5
|
UTSW |
1 |
126,027,724 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R5257:Nckap5
|
UTSW |
1 |
126,024,508 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R5277:Nckap5
|
UTSW |
1 |
126,026,540 (GRCm38) |
nonsense |
probably null |
|
|
R5512:Nckap5
|
UTSW |
1 |
126,027,744 (GRCm38) |
missense |
possibly damaging |
0.63 |
|
R5700:Nckap5
|
UTSW |
1 |
125,976,925 (GRCm38) |
critical splice donor site |
probably null |
|
|
R5789:Nckap5
|
UTSW |
1 |
126,027,702 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6029:Nckap5
|
UTSW |
1 |
126,025,786 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R6249:Nckap5
|
UTSW |
1 |
126,024,930 (GRCm38) |
missense |
probably benign |
|
|
R6292:Nckap5
|
UTSW |
1 |
125,915,015 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R6521:Nckap5
|
UTSW |
1 |
126,382,172 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6875:Nckap5
|
UTSW |
1 |
126,023,194 (GRCm38) |
missense |
probably benign |
0.03 |
|
R7017:Nckap5
|
UTSW |
1 |
126,102,661 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7018:Nckap5
|
UTSW |
1 |
126,025,048 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7054:Nckap5
|
UTSW |
1 |
126,258,712 (GRCm38) |
splice site |
probably null |
|
|
R7204:Nckap5
|
UTSW |
1 |
126,026,367 (GRCm38) |
missense |
probably benign |
|
|
R7336:Nckap5
|
UTSW |
1 |
126,026,049 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7544:Nckap5
|
UTSW |
1 |
126,026,211 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R7590:Nckap5
|
UTSW |
1 |
126,026,533 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7684:Nckap5
|
UTSW |
1 |
126,026,857 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7749:Nckap5
|
UTSW |
1 |
126,024,646 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7773:Nckap5
|
UTSW |
1 |
126,026,844 (GRCm38) |
missense |
probably benign |
0.00 |
|
R7813:Nckap5
|
UTSW |
1 |
126,025,426 (GRCm38) |
missense |
probably benign |
0.10 |
|
R7970:Nckap5
|
UTSW |
1 |
126,025,021 (GRCm38) |
nonsense |
probably null |
|
|
R7992:Nckap5
|
UTSW |
1 |
126,026,810 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8278:Nckap5
|
UTSW |
1 |
126,027,772 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8373:Nckap5
|
UTSW |
1 |
126,026,295 (GRCm38) |
missense |
probably benign |
0.02 |
|
R8414:Nckap5
|
UTSW |
1 |
126,014,620 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8755:Nckap5
|
UTSW |
1 |
126,026,542 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R8845:Nckap5
|
UTSW |
1 |
125,981,686 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
R9016:Nckap5
|
UTSW |
1 |
126,695,754 (GRCm38) |
start codon destroyed |
probably null |
0.01 |
|
R9209:Nckap5
|
UTSW |
1 |
125,940,191 (GRCm38) |
missense |
unknown |
|
|
R9214:Nckap5
|
UTSW |
1 |
126,014,639 (GRCm38) |
missense |
probably benign |
0.01 |
|
R9300:Nckap5
|
UTSW |
1 |
125,981,686 (GRCm38) |
nonsense |
probably null |
|
|
R9464:Nckap5
|
UTSW |
1 |
126,024,757 (GRCm38) |
missense |
probably benign |
0.00 |
|
R9572:Nckap5
|
UTSW |
1 |
126,027,717 (GRCm38) |
missense |
probably benign |
0.41 |
|
R9721:Nckap5
|
UTSW |
1 |
126,027,280 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R9748:Nckap5
|
UTSW |
1 |
126,026,202 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1088:Nckap5
|
UTSW |
1 |
126,024,832 (GRCm38) |
missense |
possibly damaging |
0.76 |
|
Z1176:Nckap5
|
UTSW |
1 |
126,528,681 (GRCm38) |
critical splice donor site |
probably null |
|
|
Z1177:Nckap5
|
UTSW |
1 |
126,222,659 (GRCm38) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CAGCGCGATCAATGAAATCGGC -3'
(R):5'- TCCAGCTCTCAGTAGCAGGAGAATG -3'
Sequencing Primer
(F):5'- AGGAAGTAAACAGCTCTCCTTG -3'
(R):5'- CTCAGTAGCAGGAGAATGGAAGC -3'
|
| Posted On |
2013-04-16 |
Incidental Mutation