Incidental Mutation 'R1759:N4bp2'
| ID |
195174 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
N4bp2
|
| Ensembl Gene |
ENSMUSG00000037795 |
| Gene Name |
NEDD4 binding protein 2 |
| Synonyms |
LOC333789, B3bp, LOC386488 |
| MMRRC Submission |
039791-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.190)
|
| Stock # |
R1759 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
5 |
| Chromosomal Location |
65920864-65987451 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 65983956 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Glycine
at position 1667
(E1667G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000143807
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000087264]
[ENSMUST00000201489]
|
| AlphaFold |
F8VQG7 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000087264
AA Change: E1667G
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000084519
Gene: ENSMUSG00000037795
AA Change: E1667G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
109 |
130 |
N/A |
INTRINSIC |
|
low complexity region
|
271 |
283 |
N/A |
INTRINSIC |
|
Pfam:AAA_33
|
365 |
499 |
1.1e-15 |
PFAM |
|
low complexity region
|
533 |
546 |
N/A |
INTRINSIC |
|
low complexity region
|
619 |
629 |
N/A |
INTRINSIC |
|
low complexity region
|
681 |
692 |
N/A |
INTRINSIC |
|
low complexity region
|
847 |
864 |
N/A |
INTRINSIC |
|
low complexity region
|
1079 |
1090 |
N/A |
INTRINSIC |
|
Blast:CUE
|
1430 |
1472 |
1e-9 |
BLAST |
|
low complexity region
|
1496 |
1511 |
N/A |
INTRINSIC |
|
DUF1771
|
1526 |
1591 |
1.88e-21 |
SMART |
|
SMR
|
1596 |
1678 |
1.09e-14 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000113738
AA Change: E1667G
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000109367
Gene: ENSMUSG00000037795
AA Change: E1667G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
109 |
130 |
N/A |
INTRINSIC |
|
low complexity region
|
271 |
283 |
N/A |
INTRINSIC |
|
Pfam:AAA_33
|
365 |
499 |
1e-14 |
PFAM |
|
low complexity region
|
533 |
546 |
N/A |
INTRINSIC |
|
low complexity region
|
619 |
629 |
N/A |
INTRINSIC |
|
low complexity region
|
681 |
692 |
N/A |
INTRINSIC |
|
low complexity region
|
847 |
864 |
N/A |
INTRINSIC |
|
low complexity region
|
1079 |
1090 |
N/A |
INTRINSIC |
|
Blast:CUE
|
1430 |
1472 |
1e-9 |
BLAST |
|
low complexity region
|
1496 |
1511 |
N/A |
INTRINSIC |
|
DUF1771
|
1526 |
1591 |
1.88e-21 |
SMART |
|
SMR
|
1596 |
1678 |
1.09e-14 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000201044
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000201489
AA Change: E1667G
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000143807
Gene: ENSMUSG00000037795
AA Change: E1667G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
109 |
130 |
N/A |
INTRINSIC |
|
low complexity region
|
271 |
283 |
N/A |
INTRINSIC |
|
Pfam:AAA_33
|
365 |
499 |
1e-14 |
PFAM |
|
low complexity region
|
533 |
546 |
N/A |
INTRINSIC |
|
low complexity region
|
619 |
629 |
N/A |
INTRINSIC |
|
low complexity region
|
681 |
692 |
N/A |
INTRINSIC |
|
low complexity region
|
847 |
864 |
N/A |
INTRINSIC |
|
low complexity region
|
1079 |
1090 |
N/A |
INTRINSIC |
|
Blast:CUE
|
1430 |
1472 |
1e-9 |
BLAST |
|
low complexity region
|
1496 |
1511 |
N/A |
INTRINSIC |
|
DUF1771
|
1526 |
1591 |
1.88e-21 |
SMART |
|
SMR
|
1596 |
1678 |
1.09e-14 |
SMART |
|
| Coding Region Coverage |
- 1x: 97.5%
- 3x: 96.9%
- 10x: 95.4%
- 20x: 92.5%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein containing a polynucleotide kinase domain (PNK) near the N-terminal region, and a Small MutS Related (Smr) domain near the C-terminal region. The encoded protein can bind to both B-cell leukemia/lymphoma 3 (BCL-3) and neural precursor cell expressed, developmentally downregulated 4, (Nedd4) proteins. This protein binds and hydrolyzes ATP, may function as a 5'-polynucleotide kinase, and has the capacity to be a ubiquitylation substrate. This protein may play a role in transcription-coupled DNA repair or genetic recombination. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]
|
| Allele List at MGI |
All alleles(9) : Targeted, other(2) Gene trapped(7)
|
| Other mutations in this stock |
Total: 87 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 9330159F19Rik |
A |
T |
10: 29,094,272 (GRCm39) |
M53L |
possibly damaging |
Het |
| Abca5 |
T |
C |
11: 110,184,674 (GRCm39) |
D944G |
probably benign |
Het |
| Ankdd1b |
T |
C |
13: 96,556,211 (GRCm39) |
Y433C |
probably damaging |
Het |
| Aox3 |
A |
G |
1: 58,209,805 (GRCm39) |
|
probably null |
Het |
| Ap1g1 |
G |
A |
8: 110,559,853 (GRCm39) |
G260E |
probably damaging |
Het |
| Arsi |
G |
A |
18: 61,049,723 (GRCm39) |
G202E |
probably benign |
Het |
| Atp13a4 |
T |
A |
16: 29,275,429 (GRCm39) |
T352S |
probably damaging |
Het |
| Ccdc33 |
T |
A |
9: 58,024,729 (GRCm39) |
N166Y |
possibly damaging |
Het |
| Ces2h |
T |
A |
8: 105,743,243 (GRCm39) |
D159E |
probably damaging |
Het |
| Chd1 |
T |
A |
17: 17,607,533 (GRCm39) |
D360E |
probably benign |
Het |
| Col16a1 |
G |
T |
4: 129,978,062 (GRCm39) |
G781V |
probably damaging |
Het |
| Col6a5 |
T |
A |
9: 105,808,045 (GRCm39) |
E1001V |
unknown |
Het |
| Cracdl |
A |
T |
1: 37,664,791 (GRCm39) |
I369N |
probably benign |
Het |
| Cyp3a59 |
T |
G |
5: 146,035,060 (GRCm39) |
M246R |
probably benign |
Het |
| Dcn |
T |
C |
10: 97,349,517 (GRCm39) |
V263A |
probably benign |
Het |
| Dnttip2 |
A |
G |
3: 122,069,798 (GRCm39) |
N338D |
probably benign |
Het |
| Entpd1 |
G |
T |
19: 40,600,968 (GRCm39) |
|
probably null |
Het |
| Epb41l1 |
A |
G |
2: 156,363,894 (GRCm39) |
D801G |
probably benign |
Het |
| Fam186a |
T |
A |
15: 99,864,762 (GRCm39) |
K23* |
probably null |
Het |
| Gbe1 |
T |
C |
16: 70,284,929 (GRCm39) |
M417T |
probably benign |
Het |
| Gmnc |
T |
A |
16: 26,784,497 (GRCm39) |
S3C |
possibly damaging |
Het |
| Gpr156 |
T |
C |
16: 37,768,583 (GRCm39) |
S35P |
probably damaging |
Het |
| Grid1 |
T |
C |
14: 35,167,988 (GRCm39) |
M504T |
possibly damaging |
Het |
| Gsdma3 |
T |
C |
11: 98,526,071 (GRCm39) |
V265A |
possibly damaging |
Het |
| Hsd3b3 |
A |
T |
3: 98,649,399 (GRCm39) |
I308N |
probably damaging |
Het |
| Inpp4b |
A |
G |
8: 82,494,732 (GRCm39) |
D49G |
probably benign |
Het |
| Ipmk |
C |
A |
10: 71,217,133 (GRCm39) |
Q227K |
probably damaging |
Het |
| Kalrn |
T |
A |
16: 34,181,320 (GRCm39) |
D88V |
probably damaging |
Het |
| Kansl1l |
C |
T |
1: 66,841,047 (GRCm39) |
M84I |
probably damaging |
Het |
| Kcnab2 |
T |
G |
4: 152,477,509 (GRCm39) |
K363Q |
probably damaging |
Het |
| Kdm7a |
C |
A |
6: 39,124,633 (GRCm39) |
|
probably null |
Het |
| Kiss1r |
T |
C |
10: 79,757,612 (GRCm39) |
L322P |
probably damaging |
Het |
| Lce1e |
A |
T |
3: 92,615,178 (GRCm39) |
C56* |
probably null |
Het |
| Lrpprc |
T |
C |
17: 85,047,509 (GRCm39) |
K908E |
probably damaging |
Het |
| Mak |
C |
A |
13: 41,210,110 (GRCm39) |
W42L |
probably damaging |
Het |
| Map3k21 |
A |
G |
8: 126,671,519 (GRCm39) |
T936A |
probably benign |
Het |
| Marchf7 |
C |
T |
2: 60,064,888 (GRCm39) |
S388F |
probably damaging |
Het |
| Matcap1 |
A |
T |
8: 106,012,182 (GRCm39) |
S88R |
probably damaging |
Het |
| Mgat2 |
A |
T |
12: 69,232,301 (GRCm39) |
I292F |
probably benign |
Het |
| Myh3 |
C |
A |
11: 66,987,717 (GRCm39) |
R1397S |
probably damaging |
Het |
| Myo5a |
A |
G |
9: 75,089,275 (GRCm39) |
D1135G |
possibly damaging |
Het |
| Nbr1 |
A |
G |
11: 101,450,369 (GRCm39) |
T43A |
probably damaging |
Het |
| Nip7 |
A |
G |
8: 107,784,767 (GRCm39) |
N124S |
probably benign |
Het |
| Or3a1 |
G |
A |
11: 74,225,808 (GRCm39) |
S83F |
possibly damaging |
Het |
| Or51l14 |
T |
C |
7: 103,101,356 (GRCm39) |
S271P |
probably benign |
Het |
| Or6c75 |
T |
A |
10: 129,336,775 (GRCm39) |
S7R |
probably benign |
Het |
| Or7g25 |
C |
T |
9: 19,160,384 (GRCm39) |
V104I |
probably benign |
Het |
| Or8b55 |
T |
C |
9: 38,727,194 (GRCm39) |
Y132H |
probably damaging |
Het |
| Otoa |
T |
C |
7: 120,733,326 (GRCm39) |
L731P |
probably damaging |
Het |
| Pcnx2 |
G |
A |
8: 126,500,717 (GRCm39) |
P1458S |
probably damaging |
Het |
| Pfpl |
A |
G |
19: 12,407,224 (GRCm39) |
T492A |
probably damaging |
Het |
| Pgm1 |
A |
G |
4: 99,824,305 (GRCm39) |
D326G |
probably damaging |
Het |
| Plekhh1 |
T |
A |
12: 79,119,535 (GRCm39) |
Y953N |
probably damaging |
Het |
| Pnkd |
G |
A |
1: 74,387,922 (GRCm39) |
A195T |
probably damaging |
Het |
| Ppib |
C |
T |
9: 65,968,764 (GRCm39) |
Q51* |
probably null |
Het |
| Ppip5k1 |
G |
T |
2: 121,181,067 (GRCm39) |
T13K |
probably benign |
Het |
| Psmg2 |
A |
T |
18: 67,781,246 (GRCm39) |
S113C |
probably benign |
Het |
| Rapgef2 |
A |
G |
3: 78,974,038 (GRCm39) |
M1584T |
possibly damaging |
Het |
| Rbm12b1 |
A |
C |
4: 12,145,424 (GRCm39) |
R465S |
probably damaging |
Het |
| Reln |
A |
G |
5: 22,215,287 (GRCm39) |
Y1055H |
probably damaging |
Het |
| Ros1 |
A |
T |
10: 51,996,922 (GRCm39) |
I1250K |
probably damaging |
Het |
| Samd9l |
C |
A |
6: 3,373,401 (GRCm39) |
V1287F |
probably damaging |
Het |
| Sgce |
A |
T |
6: 4,689,765 (GRCm39) |
I356N |
probably damaging |
Het |
| Sh3tc1 |
C |
T |
5: 35,863,248 (GRCm39) |
E980K |
possibly damaging |
Het |
| Sil1 |
T |
C |
18: 35,551,151 (GRCm39) |
E68G |
possibly damaging |
Het |
| Slc18a1 |
A |
G |
8: 69,518,237 (GRCm39) |
I259T |
possibly damaging |
Het |
| Slc6a20b |
A |
C |
9: 123,438,062 (GRCm39) |
|
probably null |
Het |
| Smg7 |
G |
T |
1: 152,724,597 (GRCm39) |
T536K |
probably benign |
Het |
| Smyd4 |
A |
G |
11: 75,273,192 (GRCm39) |
Y84C |
probably damaging |
Het |
| Snrnp40 |
C |
G |
4: 130,271,836 (GRCm39) |
|
probably null |
Het |
| Sorbs2 |
A |
T |
8: 46,216,056 (GRCm39) |
*50C |
probably null |
Het |
| Speg |
A |
T |
1: 75,377,806 (GRCm39) |
M855L |
possibly damaging |
Het |
| Srrt |
G |
T |
5: 137,301,212 (GRCm39) |
H71Q |
probably damaging |
Het |
| St6galnac5 |
A |
G |
3: 152,552,130 (GRCm39) |
S146P |
probably damaging |
Het |
| Syne1 |
T |
A |
10: 5,299,369 (GRCm39) |
Q962L |
probably damaging |
Het |
| Tiam2 |
A |
G |
17: 3,566,278 (GRCm39) |
H1441R |
probably damaging |
Het |
| Tmem45a |
C |
T |
16: 56,642,765 (GRCm39) |
M135I |
probably benign |
Het |
| Tpr |
A |
T |
1: 150,305,275 (GRCm39) |
E1521D |
probably benign |
Het |
| Uba3 |
C |
T |
6: 97,173,865 (GRCm39) |
G107R |
probably damaging |
Het |
| Unc45b |
G |
T |
11: 82,820,325 (GRCm39) |
V590F |
probably benign |
Het |
| Vmn1r14 |
A |
T |
6: 57,211,297 (GRCm39) |
T292S |
probably benign |
Het |
| Vmn2r102 |
T |
A |
17: 19,914,755 (GRCm39) |
N773K |
probably damaging |
Het |
| Vps13d |
A |
T |
4: 144,882,427 (GRCm39) |
D1055E |
probably benign |
Het |
| Wfs1 |
G |
C |
5: 37,124,359 (GRCm39) |
A844G |
probably damaging |
Het |
| Zfp398 |
A |
G |
6: 47,836,412 (GRCm39) |
T71A |
possibly damaging |
Het |
| Zfp507 |
C |
A |
7: 35,475,403 (GRCm39) |
A145S |
probably damaging |
Het |
| Zfp971 |
A |
T |
2: 177,675,722 (GRCm39) |
E440D |
probably damaging |
Het |
|
| Other mutations in N4bp2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00484:N4bp2
|
APN |
5 |
65,964,867 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01503:N4bp2
|
APN |
5 |
65,960,890 (GRCm39) |
nonsense |
probably null |
0.00 |
|
IGL01621:N4bp2
|
APN |
5 |
65,948,267 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02109:N4bp2
|
APN |
5 |
65,955,477 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02286:N4bp2
|
APN |
5 |
65,960,895 (GRCm39) |
missense |
probably damaging |
1.00 |
|
1mM(1):N4bp2
|
UTSW |
5 |
65,965,020 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03046:N4bp2
|
UTSW |
5 |
65,948,303 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0164:N4bp2
|
UTSW |
5 |
65,960,916 (GRCm39) |
splice site |
probably benign |
|
|
R0285:N4bp2
|
UTSW |
5 |
65,963,902 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0366:N4bp2
|
UTSW |
5 |
65,963,739 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R0548:N4bp2
|
UTSW |
5 |
65,965,496 (GRCm39) |
missense |
probably benign |
0.39 |
|
R0551:N4bp2
|
UTSW |
5 |
65,977,684 (GRCm39) |
splice site |
probably null |
|
|
R0671:N4bp2
|
UTSW |
5 |
65,964,780 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1136:N4bp2
|
UTSW |
5 |
65,965,815 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1515:N4bp2
|
UTSW |
5 |
65,947,841 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1597:N4bp2
|
UTSW |
5 |
65,964,483 (GRCm39) |
missense |
probably benign |
0.45 |
|
R1628:N4bp2
|
UTSW |
5 |
65,960,915 (GRCm39) |
splice site |
probably null |
|
|
R1722:N4bp2
|
UTSW |
5 |
65,964,225 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1735:N4bp2
|
UTSW |
5 |
65,965,659 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1745:N4bp2
|
UTSW |
5 |
65,948,165 (GRCm39) |
missense |
probably benign |
0.12 |
|
R1799:N4bp2
|
UTSW |
5 |
65,964,168 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R1846:N4bp2
|
UTSW |
5 |
65,965,862 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1872:N4bp2
|
UTSW |
5 |
65,951,861 (GRCm39) |
splice site |
probably benign |
|
|
R2042:N4bp2
|
UTSW |
5 |
65,983,964 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2082:N4bp2
|
UTSW |
5 |
65,964,908 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2101:N4bp2
|
UTSW |
5 |
65,948,224 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2147:N4bp2
|
UTSW |
5 |
65,966,543 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2251:N4bp2
|
UTSW |
5 |
65,964,071 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2507:N4bp2
|
UTSW |
5 |
65,947,404 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2508:N4bp2
|
UTSW |
5 |
65,947,404 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2919:N4bp2
|
UTSW |
5 |
65,964,441 (GRCm39) |
missense |
probably benign |
0.22 |
|
R3086:N4bp2
|
UTSW |
5 |
65,948,396 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4092:N4bp2
|
UTSW |
5 |
65,947,799 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4177:N4bp2
|
UTSW |
5 |
65,955,513 (GRCm39) |
splice site |
probably null |
|
|
R4718:N4bp2
|
UTSW |
5 |
65,960,806 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4859:N4bp2
|
UTSW |
5 |
65,982,641 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4863:N4bp2
|
UTSW |
5 |
65,965,473 (GRCm39) |
missense |
probably benign |
0.22 |
|
R4915:N4bp2
|
UTSW |
5 |
65,960,847 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4949:N4bp2
|
UTSW |
5 |
65,979,142 (GRCm39) |
splice site |
probably null |
|
|
R4978:N4bp2
|
UTSW |
5 |
65,947,583 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5029:N4bp2
|
UTSW |
5 |
65,972,123 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5079:N4bp2
|
UTSW |
5 |
65,969,320 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5097:N4bp2
|
UTSW |
5 |
65,974,561 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5158:N4bp2
|
UTSW |
5 |
65,965,805 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5228:N4bp2
|
UTSW |
5 |
65,964,861 (GRCm39) |
missense |
probably benign |
|
|
R5322:N4bp2
|
UTSW |
5 |
65,947,800 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R5554:N4bp2
|
UTSW |
5 |
65,965,457 (GRCm39) |
missense |
probably benign |
0.44 |
|
R5731:N4bp2
|
UTSW |
5 |
65,966,500 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5840:N4bp2
|
UTSW |
5 |
65,965,437 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6393:N4bp2
|
UTSW |
5 |
65,948,344 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R6767:N4bp2
|
UTSW |
5 |
65,974,530 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7103:N4bp2
|
UTSW |
5 |
65,964,189 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7112:N4bp2
|
UTSW |
5 |
65,948,050 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R7171:N4bp2
|
UTSW |
5 |
65,965,365 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7177:N4bp2
|
UTSW |
5 |
65,964,891 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7240:N4bp2
|
UTSW |
5 |
65,951,888 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7353:N4bp2
|
UTSW |
5 |
65,963,714 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7450:N4bp2
|
UTSW |
5 |
65,982,643 (GRCm39) |
nonsense |
probably null |
|
|
R7560:N4bp2
|
UTSW |
5 |
65,948,458 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7698:N4bp2
|
UTSW |
5 |
65,965,500 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7743:N4bp2
|
UTSW |
5 |
65,965,802 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7871:N4bp2
|
UTSW |
5 |
65,964,446 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7981:N4bp2
|
UTSW |
5 |
65,969,485 (GRCm39) |
missense |
probably benign |
0.41 |
|
R8065:N4bp2
|
UTSW |
5 |
65,964,639 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8067:N4bp2
|
UTSW |
5 |
65,964,639 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8164:N4bp2
|
UTSW |
5 |
65,966,566 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8166:N4bp2
|
UTSW |
5 |
65,977,655 (GRCm39) |
missense |
probably benign |
0.39 |
|
R8331:N4bp2
|
UTSW |
5 |
65,964,943 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8559:N4bp2
|
UTSW |
5 |
65,982,628 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R8806:N4bp2
|
UTSW |
5 |
65,965,551 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R9287:N4bp2
|
UTSW |
5 |
65,960,855 (GRCm39) |
missense |
probably benign |
0.38 |
|
R9369:N4bp2
|
UTSW |
5 |
65,964,259 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9460:N4bp2
|
UTSW |
5 |
65,963,886 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9462:N4bp2
|
UTSW |
5 |
65,947,898 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9605:N4bp2
|
UTSW |
5 |
65,963,879 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9641:N4bp2
|
UTSW |
5 |
65,948,035 (GRCm39) |
missense |
probably benign |
0.15 |
|
Z1177:N4bp2
|
UTSW |
5 |
65,964,980 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GAAGCCTTTTACAAGCCTTTTGGGG -3'
(R):5'- TCAACAAGTAACGGACTGGCATTTGAT -3'
Sequencing Primer
(F):5'- ATCTCTGATACAGCAGAGTCTTC -3'
(R):5'- ACAAACAACTTTCCTTGGATTCTG -3'
|
| Posted On |
2014-05-23 |
Incidental Mutation