Incidental Mutation 'R8878:Iqgap3'
| ID |
676679 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Iqgap3
|
| Ensembl Gene |
ENSMUSG00000028068 |
| Gene Name |
IQ motif containing GTPase activating protein 3 |
| Synonyms |
|
| MMRRC Submission |
068746-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.314)
|
| Stock # |
R8878 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
3 |
| Chromosomal Location |
87989309-88028355 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 88020532 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Isoleucine
at position 1290
(T1290I)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000071715
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000071812]
[ENSMUST00000194440]
[ENSMUST00000195465]
|
| AlphaFold |
F8VQ29 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000071812
AA Change: T1290I
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000071715
Gene: ENSMUSG00000028068
AA Change: T1290I
| Domain | Start | End | E-Value | Type |
|---|
|
CH
|
36 |
145 |
1.72e-14 |
SMART |
|
internal_repeat_2
|
197 |
249 |
1.75e-5 |
PROSPERO |
|
internal_repeat_1
|
209 |
418 |
1.31e-14 |
PROSPERO |
|
low complexity region
|
419 |
438 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
446 |
651 |
1.31e-14 |
PROSPERO |
|
internal_repeat_2
|
600 |
652 |
1.75e-5 |
PROSPERO |
|
IQ
|
730 |
752 |
1.18e1 |
SMART |
|
IQ
|
760 |
782 |
3.76e-6 |
SMART |
|
IQ
|
790 |
812 |
3.08e-2 |
SMART |
|
IQ
|
820 |
842 |
1.72e0 |
SMART |
|
RasGAP
|
977 |
1330 |
1.74e-57 |
SMART |
|
Blast:RasGAP
|
1338 |
1422 |
1e-9 |
BLAST |
|
Pfam:RasGAP_C
|
1434 |
1555 |
2e-36 |
PFAM |
|
low complexity region
|
1591 |
1602 |
N/A |
INTRINSIC |
|
low complexity region
|
1615 |
1630 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000194440
AA Change: T392I
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000142035
Gene: ENSMUSG00000028068
AA Change: T392I
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:RasGAP
|
1 |
67 |
3e-30 |
BLAST |
|
RasGAP
|
79 |
432 |
1e-59 |
SMART |
|
Blast:RasGAP
|
440 |
524 |
5e-10 |
BLAST |
|
Pfam:RasGAP_C
|
535 |
660 |
5.7e-30 |
PFAM |
|
low complexity region
|
693 |
704 |
N/A |
INTRINSIC |
|
low complexity region
|
717 |
732 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000195465
|
| SMART Domains |
Protein: ENSMUSP00000142013
Gene: ENSMUSG00000028068
| Domain | Start | End | E-Value | Type |
|---|
|
CH
|
36 |
145 |
8.5e-17 |
SMART |
|
internal_repeat_1
|
209 |
379 |
1.33e-7 |
PROSPERO |
|
low complexity region
|
419 |
438 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
446 |
612 |
1.33e-7 |
PROSPERO |
|
| Meta Mutation Damage Score |
0.6329 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 98.9%
|
| Validation Efficiency |
99% (73/74) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 75 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acss2 |
C |
A |
2: 155,398,324 (GRCm39) |
H348Q |
probably benign |
Het |
| Ago1 |
T |
A |
4: 126,357,516 (GRCm39) |
Y53F |
probably benign |
Het |
| Arrdc5 |
A |
G |
17: 56,601,342 (GRCm39) |
L261P |
probably benign |
Het |
| Asb2 |
C |
A |
12: 103,290,138 (GRCm39) |
W551L |
possibly damaging |
Het |
| Atl2 |
T |
C |
17: 80,160,232 (GRCm39) |
I452V |
probably benign |
Het |
| Atxn7l3 |
T |
C |
11: 102,183,545 (GRCm39) |
S203G |
probably benign |
Het |
| Bche |
A |
G |
3: 73,608,506 (GRCm39) |
F307L |
probably benign |
Het |
| C6 |
T |
C |
15: 4,826,454 (GRCm39) |
V679A |
probably benign |
Het |
| Cd163 |
A |
T |
6: 124,297,469 (GRCm39) |
N872Y |
probably damaging |
Het |
| Cdkal1 |
C |
A |
13: 29,658,607 (GRCm39) |
V380F |
probably damaging |
Het |
| Ceacam11 |
A |
T |
7: 17,709,536 (GRCm39) |
I245L |
probably benign |
Het |
| Ceacam16 |
G |
T |
7: 19,592,656 (GRCm39) |
T84K |
possibly damaging |
Het |
| Ceacam2 |
T |
A |
7: 25,227,351 (GRCm39) |
Q172L |
probably benign |
Het |
| Chga |
T |
G |
12: 102,527,720 (GRCm39) |
S125A |
possibly damaging |
Het |
| Col9a1 |
T |
C |
1: 24,236,048 (GRCm39) |
|
probably null |
Het |
| Crybg3 |
C |
A |
16: 59,380,547 (GRCm39) |
A236S |
probably benign |
Het |
| Csmd1 |
A |
G |
8: 15,960,528 (GRCm39) |
Y3296H |
probably damaging |
Het |
| Cyp2j8 |
C |
A |
4: 96,358,807 (GRCm39) |
V371L |
possibly damaging |
Het |
| Des |
C |
A |
1: 75,337,137 (GRCm39) |
L26M |
unknown |
Het |
| Edc3 |
A |
G |
9: 57,623,484 (GRCm39) |
S140G |
possibly damaging |
Het |
| Fam161a |
C |
T |
11: 22,970,092 (GRCm39) |
T90I |
probably benign |
Het |
| Fancm |
T |
C |
12: 65,173,522 (GRCm39) |
Y1945H |
probably damaging |
Het |
| Fbn2 |
C |
T |
18: 58,257,318 (GRCm39) |
V350I |
probably benign |
Het |
| Git2 |
A |
G |
5: 114,899,649 (GRCm39) |
C235R |
possibly damaging |
Het |
| Gk2 |
T |
C |
5: 97,604,341 (GRCm39) |
K166E |
probably benign |
Het |
| Gm12258 |
G |
A |
11: 58,750,112 (GRCm39) |
R429H |
unknown |
Het |
| Gm7247 |
T |
G |
14: 51,666,210 (GRCm39) |
|
probably benign |
Het |
| Gmppa |
A |
G |
1: 75,414,932 (GRCm39) |
Y59C |
probably damaging |
Het |
| Has1 |
G |
T |
17: 18,070,321 (GRCm39) |
A200E |
possibly damaging |
Het |
| Hbs1l |
T |
C |
10: 21,234,711 (GRCm39) |
I588T |
possibly damaging |
Het |
| Helz2 |
A |
G |
2: 180,874,560 (GRCm39) |
V1978A |
possibly damaging |
Het |
| Hoxb9 |
T |
C |
11: 96,165,557 (GRCm39) |
Y209H |
probably damaging |
Het |
| Hps5 |
T |
C |
7: 46,421,345 (GRCm39) |
D706G |
probably benign |
Het |
| Hydin |
T |
C |
8: 111,035,720 (GRCm39) |
V137A |
probably benign |
Het |
| Ifngr2 |
T |
C |
16: 91,359,847 (GRCm39) |
I318T |
probably benign |
Het |
| Jrk |
A |
T |
15: 74,578,988 (GRCm39) |
V99E |
probably benign |
Het |
| Kalrn |
G |
A |
16: 34,025,696 (GRCm39) |
T931M |
probably damaging |
Het |
| Kalrn |
G |
A |
16: 34,018,830 (GRCm39) |
P1311S |
probably benign |
Het |
| Kirrel3 |
A |
G |
9: 34,850,561 (GRCm39) |
|
probably benign |
Het |
| Klk1b9 |
T |
C |
7: 43,443,782 (GRCm39) |
F99L |
possibly damaging |
Het |
| Lamb3 |
T |
C |
1: 193,013,124 (GRCm39) |
C450R |
probably damaging |
Het |
| Lyst |
T |
A |
13: 13,815,661 (GRCm39) |
S1182T |
probably benign |
Het |
| Map1a |
T |
C |
2: 121,138,125 (GRCm39) |
V2933A |
probably damaging |
Het |
| Map2k5 |
A |
T |
9: 63,250,667 (GRCm39) |
|
probably null |
Het |
| Mcm6 |
A |
G |
1: 128,283,248 (GRCm39) |
|
probably null |
Het |
| Mmp17 |
G |
A |
5: 129,683,378 (GRCm39) |
V505M |
probably damaging |
Het |
| Mpped2 |
A |
G |
2: 106,575,065 (GRCm39) |
D50G |
probably damaging |
Het |
| Mtf1 |
T |
A |
4: 124,715,023 (GRCm39) |
L216* |
probably null |
Het |
| Niban2 |
A |
T |
2: 32,811,105 (GRCm39) |
M372L |
probably benign |
Het |
| Obscn |
T |
C |
11: 58,890,638 (GRCm39) |
E7298G |
unknown |
Het |
| Or52ab7 |
A |
T |
7: 102,978,212 (GRCm39) |
H173L |
possibly damaging |
Het |
| Or56a3 |
T |
C |
7: 104,735,763 (GRCm39) |
L280P |
probably damaging |
Het |
| Or6c205 |
T |
C |
10: 129,086,883 (GRCm39) |
L160P |
probably benign |
Het |
| Or7d9 |
A |
G |
9: 20,197,358 (GRCm39) |
D129G |
probably damaging |
Het |
| Otulinl |
T |
A |
15: 27,664,884 (GRCm39) |
H24L |
probably benign |
Het |
| Pax2 |
G |
A |
19: 44,777,215 (GRCm39) |
|
probably null |
Het |
| Pcnt |
T |
A |
10: 76,244,675 (GRCm39) |
E1135V |
probably damaging |
Het |
| Pgap3 |
A |
T |
11: 98,281,924 (GRCm39) |
V129D |
probably benign |
Het |
| Polq |
A |
G |
16: 36,860,869 (GRCm39) |
N497S |
probably benign |
Het |
| Ppfia4 |
T |
C |
1: 134,227,122 (GRCm39) |
T1138A |
|
Het |
| Prickle4 |
A |
G |
17: 48,001,587 (GRCm39) |
L32P |
|
Het |
| Prl2c2 |
C |
T |
13: 13,171,896 (GRCm39) |
G158R |
probably damaging |
Het |
| Psd3 |
A |
G |
8: 68,210,750 (GRCm39) |
I752T |
probably benign |
Het |
| Sag |
A |
T |
1: 87,756,158 (GRCm39) |
Y255F |
probably benign |
Het |
| Scn7a |
A |
T |
2: 66,506,199 (GRCm39) |
D1563E |
probably damaging |
Het |
| Secisbp2 |
A |
G |
13: 51,837,404 (GRCm39) |
N855S |
probably benign |
Het |
| Setd2 |
T |
C |
9: 110,421,467 (GRCm39) |
V2011A |
probably benign |
Het |
| Slc30a6 |
T |
C |
17: 74,730,112 (GRCm39) |
V334A |
probably damaging |
Het |
| Spen |
A |
G |
4: 141,204,520 (GRCm39) |
V1369A |
unknown |
Het |
| Stac2 |
T |
C |
11: 97,932,373 (GRCm39) |
T207A |
probably benign |
Het |
| Syne2 |
T |
C |
12: 75,952,067 (GRCm39) |
V445A |
probably benign |
Het |
| Tas2r131 |
C |
A |
6: 132,934,467 (GRCm39) |
W114L |
probably damaging |
Het |
| Tgfbrap1 |
G |
A |
1: 43,088,959 (GRCm39) |
R815* |
probably null |
Het |
| Trpv2 |
A |
T |
11: 62,481,112 (GRCm39) |
I404L |
probably benign |
Het |
| Zfp236 |
G |
A |
18: 82,617,122 (GRCm39) |
T1791M |
probably damaging |
Het |
|
| Other mutations in Iqgap3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01016:Iqgap3
|
APN |
3 |
88,014,867 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01062:Iqgap3
|
APN |
3 |
88,017,429 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01517:Iqgap3
|
APN |
3 |
88,016,703 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL01530:Iqgap3
|
APN |
3 |
88,019,610 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL01658:Iqgap3
|
APN |
3 |
88,023,278 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL02027:Iqgap3
|
APN |
3 |
87,994,649 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
IGL02352:Iqgap3
|
APN |
3 |
88,009,267 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02359:Iqgap3
|
APN |
3 |
88,009,267 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02522:Iqgap3
|
APN |
3 |
88,015,705 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL02717:Iqgap3
|
APN |
3 |
88,005,666 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02971:Iqgap3
|
APN |
3 |
87,997,611 (GRCm39) |
missense |
probably benign |
0.30 |
|
IGL03079:Iqgap3
|
APN |
3 |
88,020,477 (GRCm39) |
missense |
probably benign |
|
|
IGL03240:Iqgap3
|
APN |
3 |
88,022,281 (GRCm39) |
missense |
probably benign |
0.00 |
|
adjutant
|
UTSW |
3 |
88,008,834 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
Booster
|
UTSW |
3 |
88,020,435 (GRCm39) |
missense |
probably damaging |
0.99 |
|
peso_ligero
|
UTSW |
3 |
88,020,078 (GRCm39) |
frame shift |
probably null |
|
|
R0048:Iqgap3
|
UTSW |
3 |
88,023,256 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0048:Iqgap3
|
UTSW |
3 |
88,023,256 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0285:Iqgap3
|
UTSW |
3 |
88,004,297 (GRCm39) |
missense |
probably benign |
0.11 |
|
R0442:Iqgap3
|
UTSW |
3 |
88,023,266 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0490:Iqgap3
|
UTSW |
3 |
88,021,363 (GRCm39) |
splice site |
probably benign |
|
|
R0569:Iqgap3
|
UTSW |
3 |
87,998,032 (GRCm39) |
splice site |
probably benign |
|
|
R0747:Iqgap3
|
UTSW |
3 |
88,014,810 (GRCm39) |
splice site |
probably benign |
|
|
R0843:Iqgap3
|
UTSW |
3 |
88,015,738 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1260:Iqgap3
|
UTSW |
3 |
88,021,330 (GRCm39) |
missense |
probably benign |
|
|
R1465:Iqgap3
|
UTSW |
3 |
87,994,616 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1465:Iqgap3
|
UTSW |
3 |
87,994,616 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1544:Iqgap3
|
UTSW |
3 |
88,006,200 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1662:Iqgap3
|
UTSW |
3 |
88,005,708 (GRCm39) |
missense |
probably benign |
0.33 |
|
R1686:Iqgap3
|
UTSW |
3 |
88,015,663 (GRCm39) |
splice site |
probably benign |
|
|
R1748:Iqgap3
|
UTSW |
3 |
88,021,287 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1836:Iqgap3
|
UTSW |
3 |
88,015,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1972:Iqgap3
|
UTSW |
3 |
87,991,235 (GRCm39) |
splice site |
probably null |
|
|
R1973:Iqgap3
|
UTSW |
3 |
87,991,235 (GRCm39) |
splice site |
probably null |
|
|
R2051:Iqgap3
|
UTSW |
3 |
88,027,474 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2314:Iqgap3
|
UTSW |
3 |
88,023,338 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2352:Iqgap3
|
UTSW |
3 |
88,011,815 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R2857:Iqgap3
|
UTSW |
3 |
88,014,903 (GRCm39) |
nonsense |
probably null |
|
|
R2859:Iqgap3
|
UTSW |
3 |
88,014,903 (GRCm39) |
nonsense |
probably null |
|
|
R3435:Iqgap3
|
UTSW |
3 |
88,001,911 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3522:Iqgap3
|
UTSW |
3 |
87,998,089 (GRCm39) |
missense |
probably null |
0.90 |
|
R4281:Iqgap3
|
UTSW |
3 |
88,006,167 (GRCm39) |
missense |
probably benign |
0.19 |
|
R4283:Iqgap3
|
UTSW |
3 |
88,006,167 (GRCm39) |
missense |
probably benign |
0.19 |
|
R4397:Iqgap3
|
UTSW |
3 |
88,011,665 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4414:Iqgap3
|
UTSW |
3 |
88,004,293 (GRCm39) |
missense |
probably benign |
|
|
R4660:Iqgap3
|
UTSW |
3 |
88,027,483 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4872:Iqgap3
|
UTSW |
3 |
88,020,435 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4883:Iqgap3
|
UTSW |
3 |
88,014,842 (GRCm39) |
missense |
probably benign |
|
|
R4915:Iqgap3
|
UTSW |
3 |
88,008,834 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R5050:Iqgap3
|
UTSW |
3 |
87,997,493 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5130:Iqgap3
|
UTSW |
3 |
88,016,161 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5151:Iqgap3
|
UTSW |
3 |
88,025,067 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R5645:Iqgap3
|
UTSW |
3 |
88,025,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5706:Iqgap3
|
UTSW |
3 |
88,023,215 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5748:Iqgap3
|
UTSW |
3 |
88,016,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5880:Iqgap3
|
UTSW |
3 |
88,024,509 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R5982:Iqgap3
|
UTSW |
3 |
87,998,899 (GRCm39) |
nonsense |
probably null |
|
|
R6006:Iqgap3
|
UTSW |
3 |
87,998,854 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6026:Iqgap3
|
UTSW |
3 |
87,997,478 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6188:Iqgap3
|
UTSW |
3 |
88,006,200 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6211:Iqgap3
|
UTSW |
3 |
87,998,822 (GRCm39) |
missense |
probably benign |
|
|
R6291:Iqgap3
|
UTSW |
3 |
87,997,037 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6344:Iqgap3
|
UTSW |
3 |
87,989,401 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6854:Iqgap3
|
UTSW |
3 |
88,004,258 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6875:Iqgap3
|
UTSW |
3 |
88,020,078 (GRCm39) |
frame shift |
probably null |
|
|
R6877:Iqgap3
|
UTSW |
3 |
88,020,078 (GRCm39) |
frame shift |
probably null |
|
|
R6958:Iqgap3
|
UTSW |
3 |
88,020,673 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7008:Iqgap3
|
UTSW |
3 |
88,020,078 (GRCm39) |
frame shift |
probably null |
|
|
R7050:Iqgap3
|
UTSW |
3 |
88,006,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7144:Iqgap3
|
UTSW |
3 |
88,024,217 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7170:Iqgap3
|
UTSW |
3 |
88,009,370 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7288:Iqgap3
|
UTSW |
3 |
88,016,142 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7952:Iqgap3
|
UTSW |
3 |
88,005,677 (GRCm39) |
missense |
probably benign |
|
|
R8008:Iqgap3
|
UTSW |
3 |
88,016,770 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8049:Iqgap3
|
UTSW |
3 |
88,011,609 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8176:Iqgap3
|
UTSW |
3 |
88,001,957 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8190:Iqgap3
|
UTSW |
3 |
87,998,086 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8772:Iqgap3
|
UTSW |
3 |
87,997,144 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8893:Iqgap3
|
UTSW |
3 |
87,997,193 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9072:Iqgap3
|
UTSW |
3 |
88,016,773 (GRCm39) |
missense |
|
|
|
R9072:Iqgap3
|
UTSW |
3 |
87,998,883 (GRCm39) |
missense |
probably benign |
|
|
R9073:Iqgap3
|
UTSW |
3 |
88,016,773 (GRCm39) |
missense |
|
|
|
R9337:Iqgap3
|
UTSW |
3 |
88,023,425 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9489:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9492:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9593:Iqgap3
|
UTSW |
3 |
88,011,657 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9655:Iqgap3
|
UTSW |
3 |
88,016,728 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9708:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9709:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9752:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9753:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9765:Iqgap3
|
UTSW |
3 |
88,017,361 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R9771:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9772:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Iqgap3
|
UTSW |
3 |
87,996,278 (GRCm39) |
critical splice donor site |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- AGAACTGACCTGATGTGGGTGG -3'
(R):5'- TCTTCTAGGAGCTGGTGCAG -3'
Sequencing Primer
(F):5'- TGGTGGCCATCCCCATG -3'
(R):5'- AGCTGGTGCAGTGGGTC -3'
|
| Posted On |
2021-07-15 |
Incidental Mutation