Incidental Mutation 'R1748:Iqgap3'
| ID |
194103 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Iqgap3
|
| Ensembl Gene |
ENSMUSG00000028068 |
| Gene Name |
IQ motif containing GTPase activating protein 3 |
| Synonyms |
|
| MMRRC Submission |
039780-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.314)
|
| Stock # |
R1748 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
3 |
| Chromosomal Location |
87989309-88028355 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 88021287 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Alanine
at position 448
(T448A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000142035
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000071812]
[ENSMUST00000194440]
|
| AlphaFold |
F8VQ29 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000071812
AA Change: T1346A
PolyPhen 2
Score 0.860 (Sensitivity: 0.83; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000071715
Gene: ENSMUSG00000028068
AA Change: T1346A
| Domain | Start | End | E-Value | Type |
|---|
|
CH
|
36 |
145 |
1.72e-14 |
SMART |
|
internal_repeat_2
|
197 |
249 |
1.75e-5 |
PROSPERO |
|
internal_repeat_1
|
209 |
418 |
1.31e-14 |
PROSPERO |
|
low complexity region
|
419 |
438 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
446 |
651 |
1.31e-14 |
PROSPERO |
|
internal_repeat_2
|
600 |
652 |
1.75e-5 |
PROSPERO |
|
IQ
|
730 |
752 |
1.18e1 |
SMART |
|
IQ
|
760 |
782 |
3.76e-6 |
SMART |
|
IQ
|
790 |
812 |
3.08e-2 |
SMART |
|
IQ
|
820 |
842 |
1.72e0 |
SMART |
|
RasGAP
|
977 |
1330 |
1.74e-57 |
SMART |
|
Blast:RasGAP
|
1338 |
1422 |
1e-9 |
BLAST |
|
Pfam:RasGAP_C
|
1434 |
1555 |
2e-36 |
PFAM |
|
low complexity region
|
1591 |
1602 |
N/A |
INTRINSIC |
|
low complexity region
|
1615 |
1630 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000194440
AA Change: T448A
PolyPhen 2
Score 0.916 (Sensitivity: 0.81; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000142035
Gene: ENSMUSG00000028068
AA Change: T448A
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:RasGAP
|
1 |
67 |
3e-30 |
BLAST |
|
RasGAP
|
79 |
432 |
1e-59 |
SMART |
|
Blast:RasGAP
|
440 |
524 |
5e-10 |
BLAST |
|
Pfam:RasGAP_C
|
535 |
660 |
5.7e-30 |
PFAM |
|
low complexity region
|
693 |
704 |
N/A |
INTRINSIC |
|
low complexity region
|
717 |
732 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000194772
|
| Coding Region Coverage |
- 1x: 97.5%
- 3x: 96.9%
- 10x: 95.4%
- 20x: 92.8%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 76 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcc5 |
G |
T |
16: 20,152,338 (GRCm39) |
Q1403K |
probably benign |
Het |
| Adamts12 |
G |
A |
15: 11,241,548 (GRCm39) |
M373I |
probably damaging |
Het |
| Agrp |
G |
T |
8: 106,293,467 (GRCm39) |
T106K |
probably damaging |
Het |
| Aire |
T |
C |
10: 77,879,314 (GRCm39) |
H15R |
probably damaging |
Het |
| Aldh3b2 |
T |
C |
19: 4,027,572 (GRCm39) |
F38L |
probably damaging |
Het |
| Alk |
A |
C |
17: 72,910,416 (GRCm39) |
C97G |
probably benign |
Het |
| Ano8 |
T |
C |
8: 71,931,602 (GRCm39) |
|
probably benign |
Het |
| Anpep |
C |
T |
7: 79,488,004 (GRCm39) |
E518K |
probably benign |
Het |
| Arsk |
T |
A |
13: 76,210,529 (GRCm39) |
H506L |
probably benign |
Het |
| Asgr2 |
G |
T |
11: 69,987,658 (GRCm39) |
R52L |
probably damaging |
Het |
| Atp2a1 |
A |
G |
7: 126,058,780 (GRCm39) |
I145T |
possibly damaging |
Het |
| Atrnl1 |
A |
G |
19: 57,703,134 (GRCm39) |
T1051A |
probably damaging |
Het |
| Cacna1e |
A |
T |
1: 154,362,315 (GRCm39) |
V424D |
possibly damaging |
Het |
| Capn3 |
T |
C |
2: 120,327,494 (GRCm39) |
V574A |
probably benign |
Het |
| Capzb |
C |
A |
4: 138,984,679 (GRCm39) |
D67E |
probably damaging |
Het |
| Ccdc68 |
A |
T |
18: 70,089,062 (GRCm39) |
T202S |
probably benign |
Het |
| Ccser2 |
T |
C |
14: 36,618,270 (GRCm39) |
K123R |
probably damaging |
Het |
| Ccser2 |
T |
A |
14: 36,618,271 (GRCm39) |
K123* |
probably null |
Het |
| Ces2h |
T |
C |
8: 105,744,473 (GRCm39) |
I316T |
probably benign |
Het |
| Chd3 |
T |
G |
11: 69,255,523 (GRCm39) |
K122Q |
possibly damaging |
Het |
| Col12a1 |
T |
C |
9: 79,580,279 (GRCm39) |
T1533A |
probably benign |
Het |
| Cr2 |
T |
A |
1: 194,838,213 (GRCm39) |
K1084* |
probably null |
Het |
| Ddx28 |
A |
G |
8: 106,737,314 (GRCm39) |
L248P |
probably benign |
Het |
| Depdc5 |
A |
G |
5: 33,075,286 (GRCm39) |
E488G |
probably benign |
Het |
| Dld |
T |
C |
12: 31,384,745 (GRCm39) |
T305A |
probably benign |
Het |
| Dok5 |
T |
A |
2: 170,683,373 (GRCm39) |
F211L |
probably damaging |
Het |
| Duox2 |
T |
C |
2: 122,117,532 (GRCm39) |
D934G |
probably benign |
Het |
| Eif3a |
G |
A |
19: 60,755,236 (GRCm39) |
T982I |
unknown |
Het |
| Erbb2 |
G |
T |
11: 98,326,161 (GRCm39) |
R979L |
probably benign |
Het |
| Espl1 |
G |
T |
15: 102,206,964 (GRCm39) |
V143L |
possibly damaging |
Het |
| Fanci |
T |
C |
7: 79,080,236 (GRCm39) |
L598P |
probably damaging |
Het |
| Fat2 |
T |
A |
11: 55,147,473 (GRCm39) |
E3923V |
probably damaging |
Het |
| Fhod3 |
A |
T |
18: 24,903,550 (GRCm39) |
K95* |
probably null |
Het |
| Gpr108 |
G |
T |
17: 57,543,217 (GRCm39) |
T484K |
probably damaging |
Het |
| Hao1 |
T |
A |
2: 134,340,238 (GRCm39) |
N351I |
possibly damaging |
Het |
| Hepacam |
A |
T |
9: 37,295,189 (GRCm39) |
N308I |
possibly damaging |
Het |
| Herc2 |
T |
C |
7: 55,798,571 (GRCm39) |
|
probably null |
Het |
| Hltf |
T |
C |
3: 20,130,685 (GRCm39) |
I301T |
probably benign |
Het |
| Igsf10 |
A |
T |
3: 59,226,514 (GRCm39) |
N2386K |
probably damaging |
Het |
| Ikbke |
G |
T |
1: 131,186,937 (GRCm39) |
T585K |
probably benign |
Het |
| Kl |
T |
C |
5: 150,904,450 (GRCm39) |
S401P |
possibly damaging |
Het |
| Lama4 |
T |
C |
10: 38,941,615 (GRCm39) |
V684A |
probably benign |
Het |
| Lgals8 |
A |
T |
13: 12,469,824 (GRCm39) |
F45Y |
probably damaging |
Het |
| Lgalsl |
G |
A |
11: 20,776,491 (GRCm39) |
R134C |
probably benign |
Het |
| Lmcd1 |
T |
C |
6: 112,306,875 (GRCm39) |
V349A |
probably benign |
Het |
| Lrp1b |
T |
A |
2: 41,618,718 (GRCm39) |
N119Y |
possibly damaging |
Het |
| Lrrc73 |
T |
A |
17: 46,566,621 (GRCm39) |
I157N |
probably damaging |
Het |
| Map3k8 |
A |
G |
18: 4,334,766 (GRCm39) |
Y293H |
probably damaging |
Het |
| Mybphl |
A |
T |
3: 108,282,400 (GRCm39) |
|
probably null |
Het |
| Naa12 |
T |
C |
18: 80,255,161 (GRCm39) |
S152P |
probably benign |
Het |
| Ndrg1 |
A |
G |
15: 66,802,930 (GRCm39) |
M140T |
possibly damaging |
Het |
| Or2n1e |
T |
A |
17: 38,585,997 (GRCm39) |
C112S |
possibly damaging |
Het |
| Or8b38 |
A |
G |
9: 37,972,796 (GRCm39) |
Y60C |
probably damaging |
Het |
| Pbx2 |
T |
C |
17: 34,812,951 (GRCm39) |
S76P |
possibly damaging |
Het |
| Plcl2 |
T |
A |
17: 50,913,826 (GRCm39) |
S278R |
probably benign |
Het |
| Polr3d |
A |
T |
14: 70,676,915 (GRCm39) |
L393* |
probably null |
Het |
| Prmt6 |
T |
C |
3: 110,157,683 (GRCm39) |
Q202R |
probably benign |
Het |
| Rif1 |
GCCACCA |
GCCA |
2: 52,000,336 (GRCm39) |
|
probably benign |
Het |
| Sag |
T |
A |
1: 87,759,662 (GRCm39) |
I300N |
probably damaging |
Het |
| Sap25 |
T |
A |
5: 137,640,180 (GRCm39) |
|
probably null |
Het |
| Scarb2 |
A |
G |
5: 92,608,695 (GRCm39) |
L177P |
probably damaging |
Het |
| Sh3pxd2b |
A |
T |
11: 32,372,203 (GRCm39) |
N457Y |
possibly damaging |
Het |
| Siae |
T |
A |
9: 37,542,902 (GRCm39) |
|
probably null |
Het |
| Slc36a1 |
T |
C |
11: 55,119,150 (GRCm39) |
L375P |
probably damaging |
Het |
| Smg8 |
A |
G |
11: 86,976,594 (GRCm39) |
V329A |
probably damaging |
Het |
| Tas2r113 |
A |
T |
6: 132,870,695 (GRCm39) |
Y241F |
probably damaging |
Het |
| Tm9sf3 |
T |
G |
19: 41,244,668 (GRCm39) |
S70R |
probably benign |
Het |
| Tmem144 |
C |
T |
3: 79,732,594 (GRCm39) |
S228N |
probably damaging |
Het |
| Tmem45a |
C |
A |
16: 56,642,701 (GRCm39) |
V157F |
possibly damaging |
Het |
| Tpbg |
G |
T |
9: 85,726,429 (GRCm39) |
V133L |
probably damaging |
Het |
| Trpv3 |
G |
A |
11: 73,186,209 (GRCm39) |
V667I |
possibly damaging |
Het |
| Ube2c |
T |
C |
2: 164,613,241 (GRCm39) |
F53S |
probably damaging |
Het |
| Vmn1r78 |
T |
A |
7: 11,887,250 (GRCm39) |
V287D |
probably damaging |
Het |
| Vmn2r114 |
T |
A |
17: 23,527,035 (GRCm39) |
D499V |
probably benign |
Het |
| Zpld2 |
C |
G |
4: 133,927,610 (GRCm39) |
C381S |
probably damaging |
Het |
| Zpld2 |
T |
A |
4: 133,929,430 (GRCm39) |
T292S |
possibly damaging |
Het |
|
| Other mutations in Iqgap3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01016:Iqgap3
|
APN |
3 |
88,014,867 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01062:Iqgap3
|
APN |
3 |
88,017,429 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01517:Iqgap3
|
APN |
3 |
88,016,703 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL01530:Iqgap3
|
APN |
3 |
88,019,610 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL01658:Iqgap3
|
APN |
3 |
88,023,278 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL02027:Iqgap3
|
APN |
3 |
87,994,649 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
IGL02352:Iqgap3
|
APN |
3 |
88,009,267 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02359:Iqgap3
|
APN |
3 |
88,009,267 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02522:Iqgap3
|
APN |
3 |
88,015,705 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL02717:Iqgap3
|
APN |
3 |
88,005,666 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02971:Iqgap3
|
APN |
3 |
87,997,611 (GRCm39) |
missense |
probably benign |
0.30 |
|
IGL03079:Iqgap3
|
APN |
3 |
88,020,477 (GRCm39) |
missense |
probably benign |
|
|
IGL03240:Iqgap3
|
APN |
3 |
88,022,281 (GRCm39) |
missense |
probably benign |
0.00 |
|
adjutant
|
UTSW |
3 |
88,008,834 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
Booster
|
UTSW |
3 |
88,020,435 (GRCm39) |
missense |
probably damaging |
0.99 |
|
peso_ligero
|
UTSW |
3 |
88,020,078 (GRCm39) |
frame shift |
probably null |
|
|
R0048:Iqgap3
|
UTSW |
3 |
88,023,256 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0048:Iqgap3
|
UTSW |
3 |
88,023,256 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0285:Iqgap3
|
UTSW |
3 |
88,004,297 (GRCm39) |
missense |
probably benign |
0.11 |
|
R0442:Iqgap3
|
UTSW |
3 |
88,023,266 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0490:Iqgap3
|
UTSW |
3 |
88,021,363 (GRCm39) |
splice site |
probably benign |
|
|
R0569:Iqgap3
|
UTSW |
3 |
87,998,032 (GRCm39) |
splice site |
probably benign |
|
|
R0747:Iqgap3
|
UTSW |
3 |
88,014,810 (GRCm39) |
splice site |
probably benign |
|
|
R0843:Iqgap3
|
UTSW |
3 |
88,015,738 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1260:Iqgap3
|
UTSW |
3 |
88,021,330 (GRCm39) |
missense |
probably benign |
|
|
R1465:Iqgap3
|
UTSW |
3 |
87,994,616 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1465:Iqgap3
|
UTSW |
3 |
87,994,616 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1544:Iqgap3
|
UTSW |
3 |
88,006,200 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1662:Iqgap3
|
UTSW |
3 |
88,005,708 (GRCm39) |
missense |
probably benign |
0.33 |
|
R1686:Iqgap3
|
UTSW |
3 |
88,015,663 (GRCm39) |
splice site |
probably benign |
|
|
R1836:Iqgap3
|
UTSW |
3 |
88,015,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1972:Iqgap3
|
UTSW |
3 |
87,991,235 (GRCm39) |
splice site |
probably null |
|
|
R1973:Iqgap3
|
UTSW |
3 |
87,991,235 (GRCm39) |
splice site |
probably null |
|
|
R2051:Iqgap3
|
UTSW |
3 |
88,027,474 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2314:Iqgap3
|
UTSW |
3 |
88,023,338 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2352:Iqgap3
|
UTSW |
3 |
88,011,815 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R2857:Iqgap3
|
UTSW |
3 |
88,014,903 (GRCm39) |
nonsense |
probably null |
|
|
R2859:Iqgap3
|
UTSW |
3 |
88,014,903 (GRCm39) |
nonsense |
probably null |
|
|
R3435:Iqgap3
|
UTSW |
3 |
88,001,911 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3522:Iqgap3
|
UTSW |
3 |
87,998,089 (GRCm39) |
missense |
probably null |
0.90 |
|
R4281:Iqgap3
|
UTSW |
3 |
88,006,167 (GRCm39) |
missense |
probably benign |
0.19 |
|
R4283:Iqgap3
|
UTSW |
3 |
88,006,167 (GRCm39) |
missense |
probably benign |
0.19 |
|
R4397:Iqgap3
|
UTSW |
3 |
88,011,665 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4414:Iqgap3
|
UTSW |
3 |
88,004,293 (GRCm39) |
missense |
probably benign |
|
|
R4660:Iqgap3
|
UTSW |
3 |
88,027,483 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4872:Iqgap3
|
UTSW |
3 |
88,020,435 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4883:Iqgap3
|
UTSW |
3 |
88,014,842 (GRCm39) |
missense |
probably benign |
|
|
R4915:Iqgap3
|
UTSW |
3 |
88,008,834 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R5050:Iqgap3
|
UTSW |
3 |
87,997,493 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5130:Iqgap3
|
UTSW |
3 |
88,016,161 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5151:Iqgap3
|
UTSW |
3 |
88,025,067 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R5645:Iqgap3
|
UTSW |
3 |
88,025,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5706:Iqgap3
|
UTSW |
3 |
88,023,215 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5748:Iqgap3
|
UTSW |
3 |
88,016,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5880:Iqgap3
|
UTSW |
3 |
88,024,509 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R5982:Iqgap3
|
UTSW |
3 |
87,998,899 (GRCm39) |
nonsense |
probably null |
|
|
R6006:Iqgap3
|
UTSW |
3 |
87,998,854 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6026:Iqgap3
|
UTSW |
3 |
87,997,478 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6188:Iqgap3
|
UTSW |
3 |
88,006,200 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6211:Iqgap3
|
UTSW |
3 |
87,998,822 (GRCm39) |
missense |
probably benign |
|
|
R6291:Iqgap3
|
UTSW |
3 |
87,997,037 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6344:Iqgap3
|
UTSW |
3 |
87,989,401 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6854:Iqgap3
|
UTSW |
3 |
88,004,258 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6875:Iqgap3
|
UTSW |
3 |
88,020,078 (GRCm39) |
frame shift |
probably null |
|
|
R6877:Iqgap3
|
UTSW |
3 |
88,020,078 (GRCm39) |
frame shift |
probably null |
|
|
R6958:Iqgap3
|
UTSW |
3 |
88,020,673 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7008:Iqgap3
|
UTSW |
3 |
88,020,078 (GRCm39) |
frame shift |
probably null |
|
|
R7050:Iqgap3
|
UTSW |
3 |
88,006,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7144:Iqgap3
|
UTSW |
3 |
88,024,217 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7170:Iqgap3
|
UTSW |
3 |
88,009,370 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7288:Iqgap3
|
UTSW |
3 |
88,016,142 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7952:Iqgap3
|
UTSW |
3 |
88,005,677 (GRCm39) |
missense |
probably benign |
|
|
R8008:Iqgap3
|
UTSW |
3 |
88,016,770 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8049:Iqgap3
|
UTSW |
3 |
88,011,609 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8176:Iqgap3
|
UTSW |
3 |
88,001,957 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8190:Iqgap3
|
UTSW |
3 |
87,998,086 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8772:Iqgap3
|
UTSW |
3 |
87,997,144 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8878:Iqgap3
|
UTSW |
3 |
88,020,532 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8893:Iqgap3
|
UTSW |
3 |
87,997,193 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9072:Iqgap3
|
UTSW |
3 |
88,016,773 (GRCm39) |
missense |
|
|
|
R9072:Iqgap3
|
UTSW |
3 |
87,998,883 (GRCm39) |
missense |
probably benign |
|
|
R9073:Iqgap3
|
UTSW |
3 |
88,016,773 (GRCm39) |
missense |
|
|
|
R9337:Iqgap3
|
UTSW |
3 |
88,023,425 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9489:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9492:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9593:Iqgap3
|
UTSW |
3 |
88,011,657 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9655:Iqgap3
|
UTSW |
3 |
88,016,728 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9708:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9709:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9752:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9753:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9765:Iqgap3
|
UTSW |
3 |
88,017,361 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R9771:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9772:Iqgap3
|
UTSW |
3 |
88,016,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Iqgap3
|
UTSW |
3 |
87,996,278 (GRCm39) |
critical splice donor site |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GACTGATGTACACAGACTCACAGCC -3'
(R):5'- GCAACAAGGAAGTATGACAGCCCTC -3'
Sequencing Primer
(F):5'- AGGTGTCTAGCTCTGGAACC -3'
(R):5'- GAAGTATGACAGCCCTCTCTGAG -3'
|
| Posted On |
2014-05-23 |
Incidental Mutation