Incidental Mutation 'R9497:Obsl1'
| ID |
717253 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Obsl1
|
| Ensembl Gene |
ENSMUSG00000026211 |
| Gene Name |
obscurin-like 1 |
| Synonyms |
|
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.269)
|
| Stock # |
R9497 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
1 |
| Chromosomal Location |
75462469-75483134 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 75467484 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Cysteine to Tyrosine
at position 1430
(C1430Y)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000109197
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000113567]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000113567
AA Change: C1430Y
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000109197
Gene: ENSMUSG00000026211
AA Change: C1430Y
| Domain | Start | End | E-Value | Type |
|---|
|
IGc2
|
24 |
91 |
1.23e-12 |
SMART |
|
IGc2
|
140 |
216 |
2.33e-13 |
SMART |
|
IGc2
|
258 |
326 |
1.48e-6 |
SMART |
|
IG
|
347 |
427 |
9.49e-5 |
SMART |
|
IG
|
435 |
511 |
1.04e-1 |
SMART |
|
FN3
|
518 |
601 |
6.6e-2 |
SMART |
|
PDB:2E6Q|A
|
608 |
714 |
8e-57 |
PDB |
|
Blast:IG_like
|
622 |
711 |
3e-50 |
BLAST |
|
IG
|
723 |
804 |
3.79e-4 |
SMART |
|
IG
|
814 |
893 |
2.58e-6 |
SMART |
|
IGc2
|
911 |
977 |
1.12e-6 |
SMART |
|
IG
|
996 |
1075 |
1.27e-5 |
SMART |
|
IGc2
|
1094 |
1160 |
4.07e-4 |
SMART |
|
IGc2
|
1186 |
1252 |
9.49e-5 |
SMART |
|
IG
|
1274 |
1353 |
7.41e-7 |
SMART |
|
IG
|
1363 |
1444 |
1.15e-3 |
SMART |
|
IG
|
1454 |
1533 |
8.33e-1 |
SMART |
|
IGc2
|
1549 |
1615 |
8.72e-4 |
SMART |
|
IG
|
1633 |
1712 |
1e-3 |
SMART |
|
IG
|
1723 |
1802 |
3.82e-9 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000132252
|
| SMART Domains |
Protein: ENSMUSP00000117420
Gene: ENSMUSG00000026211
| Domain | Start | End | E-Value | Type |
|---|
|
IG_like
|
1 |
59 |
2.8e-1 |
SMART |
|
IGc2
|
85 |
151 |
9.49e-5 |
SMART |
|
IG
|
175 |
254 |
2.64e-3 |
SMART |
|
IG
|
265 |
344 |
7.41e-7 |
SMART |
|
Blast:IG
|
354 |
417 |
4e-35 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000155084
|
| SMART Domains |
Protein: ENSMUSP00000114553
Gene: ENSMUSG00000026211
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1g1ca_
|
2 |
32 |
1e-3 |
SMART |
|
IGc2
|
64 |
132 |
1.48e-6 |
SMART |
|
IG
|
153 |
233 |
9.49e-5 |
SMART |
|
IG
|
241 |
317 |
1.04e-1 |
SMART |
|
FN3
|
324 |
407 |
6.6e-2 |
SMART |
|
PDB:2E6Q|A
|
414 |
520 |
4e-57 |
PDB |
|
Blast:IG_like
|
428 |
517 |
2e-50 |
BLAST |
|
IG
|
529 |
610 |
3.79e-4 |
SMART |
|
IG
|
620 |
699 |
2.58e-6 |
SMART |
|
IGc2
|
717 |
783 |
1.12e-6 |
SMART |
|
IG
|
802 |
881 |
1.27e-5 |
SMART |
|
IGc2
|
900 |
966 |
4.07e-4 |
SMART |
|
IGc2
|
992 |
1058 |
9.49e-5 |
SMART |
|
IG
|
1080 |
1159 |
7.41e-7 |
SMART |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.6%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 83 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2810459M11Rik |
A |
C |
1: 85,973,893 (GRCm39) |
E70A |
possibly damaging |
Het |
| Abcb5 |
C |
A |
12: 118,899,850 (GRCm39) |
Q272H |
probably damaging |
Het |
| Acoxl |
T |
C |
2: 127,719,706 (GRCm39) |
Y156H |
probably damaging |
Het |
| Alg9 |
T |
C |
9: 50,711,436 (GRCm39) |
F305L |
probably damaging |
Het |
| Apobec4 |
T |
C |
1: 152,632,947 (GRCm39) |
V325A |
probably benign |
Het |
| Aqp9 |
T |
G |
9: 71,069,651 (GRCm39) |
D46A |
probably benign |
Het |
| Atp13a4 |
T |
A |
16: 29,288,130 (GRCm39) |
|
probably null |
Het |
| BC051019 |
A |
G |
7: 109,315,466 (GRCm39) |
F263S |
probably damaging |
Het |
| Bicc1 |
A |
T |
10: 70,776,828 (GRCm39) |
|
probably null |
Het |
| Birc2 |
G |
A |
9: 7,861,028 (GRCm39) |
Q97* |
probably null |
Het |
| Capn13 |
G |
T |
17: 73,633,362 (GRCm39) |
T533N |
probably benign |
Het |
| Casp6 |
G |
A |
3: 129,699,559 (GRCm39) |
V13M |
probably benign |
Het |
| Cdh10 |
A |
T |
15: 18,964,267 (GRCm39) |
E143V |
probably damaging |
Het |
| Cobl |
T |
A |
11: 12,203,501 (GRCm39) |
Q1067L |
probably benign |
Het |
| Cr2 |
A |
G |
1: 194,850,743 (GRCm39) |
V241A |
probably damaging |
Het |
| Cyp2c23 |
C |
T |
19: 44,010,085 (GRCm39) |
V87M |
probably damaging |
Het |
| Cyp2j9 |
G |
A |
4: 96,460,211 (GRCm39) |
Q431* |
probably null |
Het |
| Cyp2t4 |
G |
A |
7: 26,854,717 (GRCm39) |
V66M |
possibly damaging |
Het |
| Cyp4a12b |
A |
T |
4: 115,271,768 (GRCm39) |
M160L |
probably benign |
Het |
| Ddhd2 |
T |
A |
8: 26,217,731 (GRCm39) |
K715N |
possibly damaging |
Het |
| Ecscr |
T |
C |
18: 35,851,436 (GRCm39) |
Y32C |
probably damaging |
Het |
| Ednra |
A |
T |
8: 78,446,934 (GRCm39) |
L48Q |
probably benign |
Het |
| Eya4 |
C |
T |
10: 22,987,458 (GRCm39) |
|
probably null |
Het |
| F13a1 |
C |
A |
13: 37,082,118 (GRCm39) |
V529L |
probably benign |
Het |
| Fam151b |
A |
T |
13: 92,610,621 (GRCm39) |
I56K |
probably damaging |
Het |
| Fat3 |
A |
G |
9: 15,903,504 (GRCm39) |
I2997T |
probably damaging |
Het |
| Fgfr2 |
A |
T |
7: 129,765,763 (GRCm39) |
F817I |
probably damaging |
Het |
| Fras1 |
G |
T |
5: 96,884,895 (GRCm39) |
C2591F |
probably damaging |
Het |
| Fryl |
T |
C |
5: 73,215,134 (GRCm39) |
D2214G |
|
Het |
| Galntl6 |
A |
T |
8: 58,290,410 (GRCm39) |
D394E |
probably damaging |
Het |
| Ggcx |
C |
A |
6: 72,406,190 (GRCm39) |
N605K |
probably damaging |
Het |
| Gja5 |
A |
G |
3: 96,958,801 (GRCm39) |
N286S |
|
Het |
| Gm4553 |
A |
T |
7: 141,719,298 (GRCm39) |
C43* |
probably null |
Het |
| Gpr158 |
T |
C |
2: 21,831,825 (GRCm39) |
V975A |
probably benign |
Het |
| Greb1l |
T |
A |
18: 10,458,600 (GRCm39) |
D60E |
probably benign |
Het |
| Hao2 |
A |
T |
3: 98,784,462 (GRCm39) |
L301H |
probably damaging |
Het |
| Hic1 |
A |
G |
11: 75,060,131 (GRCm39) |
L72P |
possibly damaging |
Het |
| Hs3st5 |
A |
C |
10: 36,709,370 (GRCm39) |
N302H |
probably benign |
Het |
| Htr1d |
A |
G |
4: 136,169,663 (GRCm39) |
|
probably benign |
Het |
| Inka1 |
A |
G |
9: 107,861,938 (GRCm39) |
V128A |
probably benign |
Het |
| Kdm7a |
T |
C |
6: 39,128,253 (GRCm39) |
D526G |
probably damaging |
Het |
| Kif5a |
T |
C |
10: 127,079,353 (GRCm39) |
S282G |
probably damaging |
Het |
| Klhdc7b |
T |
C |
15: 89,272,463 (GRCm39) |
V457A |
possibly damaging |
Het |
| Lcorl |
A |
G |
5: 45,891,339 (GRCm39) |
V421A |
probably benign |
Het |
| Ltc4s |
A |
G |
11: 50,127,386 (GRCm39) |
S150P |
unknown |
Het |
| Mdfic |
C |
T |
6: 15,720,852 (GRCm39) |
R18W |
unknown |
Het |
| Mdfic |
T |
G |
6: 15,770,508 (GRCm39) |
D171E |
probably benign |
Het |
| Meis2 |
T |
C |
2: 115,694,724 (GRCm39) |
D473G |
possibly damaging |
Het |
| Mettl17 |
A |
T |
14: 52,129,029 (GRCm39) |
Q433L |
unknown |
Het |
| Mettl25 |
T |
C |
10: 105,677,090 (GRCm39) |
R31G |
probably damaging |
Het |
| Mroh2b |
T |
A |
15: 4,950,845 (GRCm39) |
I581N |
probably damaging |
Het |
| Myh7 |
A |
T |
14: 55,217,841 (GRCm39) |
N1091K |
probably benign |
Het |
| Mysm1 |
T |
C |
4: 94,848,635 (GRCm39) |
D466G |
probably benign |
Het |
| Ncoa6 |
T |
C |
2: 155,248,238 (GRCm39) |
T1689A |
probably damaging |
Het |
| Ndfip2 |
A |
G |
14: 105,542,245 (GRCm39) |
T332A |
probably benign |
Het |
| Nfkbil1 |
G |
A |
17: 35,439,605 (GRCm39) |
P303S |
probably damaging |
Het |
| Nfx1 |
T |
G |
4: 40,994,104 (GRCm39) |
N604K |
probably benign |
Het |
| Npb |
T |
C |
11: 120,499,473 (GRCm39) |
F47L |
probably benign |
Het |
| Nr2c2 |
C |
T |
6: 92,133,673 (GRCm39) |
T259I |
possibly damaging |
Het |
| Nt5el |
G |
T |
13: 105,236,987 (GRCm39) |
L79F |
probably damaging |
Het |
| Or10al5 |
T |
A |
17: 38,062,942 (GRCm39) |
Y66N |
probably damaging |
Het |
| Or10b1 |
A |
G |
10: 78,355,738 (GRCm39) |
I99V |
probably benign |
Het |
| Or10g6 |
A |
T |
9: 39,934,616 (GRCm39) |
H309L |
probably benign |
Het |
| Or4d5 |
G |
A |
9: 40,011,935 (GRCm39) |
P284S |
probably damaging |
Het |
| Or4n4b |
C |
T |
14: 50,536,362 (GRCm39) |
V135I |
probably benign |
Het |
| Or6c202 |
C |
A |
10: 128,996,464 (GRCm39) |
V130L |
probably benign |
Het |
| Or6f1 |
G |
A |
7: 85,970,989 (GRCm39) |
T57M |
probably damaging |
Het |
| Pdcd6 |
A |
T |
13: 74,453,695 (GRCm39) |
F148I |
probably damaging |
Het |
| Pih1d1 |
A |
T |
7: 44,803,789 (GRCm39) |
Q16L |
unknown |
Het |
| Ppp1r10 |
T |
C |
17: 36,235,786 (GRCm39) |
S123P |
probably damaging |
Het |
| Ppp1r13b |
A |
T |
12: 111,807,446 (GRCm39) |
M305K |
probably benign |
Het |
| Prg2 |
A |
G |
2: 84,811,685 (GRCm39) |
K2E |
possibly damaging |
Het |
| Prkd1 |
A |
T |
12: 50,438,107 (GRCm39) |
|
probably null |
Het |
| Rfx7 |
T |
A |
9: 72,526,423 (GRCm39) |
H1204Q |
probably benign |
Het |
| Serpina3k |
A |
C |
12: 104,309,430 (GRCm39) |
Q291H |
probably benign |
Het |
| Tafa4 |
T |
A |
6: 96,820,831 (GRCm39) |
I93F |
possibly damaging |
Het |
| Tas2r107 |
G |
T |
6: 131,636,549 (GRCm39) |
Q167K |
probably benign |
Het |
| Tle1 |
A |
C |
4: 72,071,135 (GRCm39) |
|
probably benign |
Het |
| Tm7sf3 |
C |
T |
6: 146,525,179 (GRCm39) |
D89N |
possibly damaging |
Het |
| Trpa1 |
C |
T |
1: 14,989,026 (GRCm39) |
E12K |
probably benign |
Het |
| Vmn2r7 |
T |
C |
3: 64,614,474 (GRCm39) |
T447A |
probably benign |
Het |
| Wdr86 |
T |
C |
5: 24,920,538 (GRCm39) |
Y283C |
probably benign |
Het |
| Zfp329 |
A |
T |
7: 12,544,215 (GRCm39) |
Y436* |
probably null |
Het |
|
| Other mutations in Obsl1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00504:Obsl1
|
APN |
1 |
75,467,518 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01111:Obsl1
|
APN |
1 |
75,473,789 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
IGL01140:Obsl1
|
APN |
1 |
75,466,400 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02149:Obsl1
|
APN |
1 |
75,480,464 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02225:Obsl1
|
APN |
1 |
75,480,442 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02269:Obsl1
|
APN |
1 |
75,464,357 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02296:Obsl1
|
APN |
1 |
75,474,793 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL02386:Obsl1
|
APN |
1 |
75,469,161 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02408:Obsl1
|
APN |
1 |
75,481,890 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02601:Obsl1
|
APN |
1 |
75,466,264 (GRCm39) |
missense |
probably benign |
|
|
IGL03053:Obsl1
|
APN |
1 |
75,469,723 (GRCm39) |
missense |
probably benign |
|
|
IGL03181:Obsl1
|
APN |
1 |
75,469,228 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03402:Obsl1
|
APN |
1 |
75,463,443 (GRCm39) |
missense |
probably benign |
0.00 |
|
Jude
|
UTSW |
1 |
75,474,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT1430001:Obsl1
|
UTSW |
1 |
75,482,811 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4382001:Obsl1
|
UTSW |
1 |
75,464,607 (GRCm39) |
missense |
probably benign |
0.06 |
|
R0281:Obsl1
|
UTSW |
1 |
75,469,571 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1343:Obsl1
|
UTSW |
1 |
75,469,223 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1394:Obsl1
|
UTSW |
1 |
75,469,309 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1395:Obsl1
|
UTSW |
1 |
75,469,309 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1439:Obsl1
|
UTSW |
1 |
75,463,428 (GRCm39) |
nonsense |
probably null |
|
|
R1456:Obsl1
|
UTSW |
1 |
75,464,300 (GRCm39) |
nonsense |
probably null |
|
|
R1728:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1729:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1730:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1739:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1757:Obsl1
|
UTSW |
1 |
75,470,527 (GRCm39) |
missense |
probably benign |
|
|
R1762:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1783:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1784:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1785:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1851:Obsl1
|
UTSW |
1 |
75,469,537 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1864:Obsl1
|
UTSW |
1 |
75,469,753 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1873:Obsl1
|
UTSW |
1 |
75,474,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1875:Obsl1
|
UTSW |
1 |
75,474,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1980:Obsl1
|
UTSW |
1 |
75,482,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1985:Obsl1
|
UTSW |
1 |
75,482,244 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2049:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R2069:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R2122:Obsl1
|
UTSW |
1 |
75,470,527 (GRCm39) |
missense |
probably benign |
|
|
R2141:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R2142:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R2184:Obsl1
|
UTSW |
1 |
75,478,861 (GRCm39) |
missense |
probably benign |
0.26 |
|
R2267:Obsl1
|
UTSW |
1 |
75,482,342 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2883:Obsl1
|
UTSW |
1 |
75,473,155 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R3079:Obsl1
|
UTSW |
1 |
75,467,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3749:Obsl1
|
UTSW |
1 |
75,474,890 (GRCm39) |
missense |
probably benign |
|
|
R4002:Obsl1
|
UTSW |
1 |
75,476,743 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R4365:Obsl1
|
UTSW |
1 |
75,464,693 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R4366:Obsl1
|
UTSW |
1 |
75,464,693 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R4414:Obsl1
|
UTSW |
1 |
75,467,546 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4700:Obsl1
|
UTSW |
1 |
75,480,085 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4799:Obsl1
|
UTSW |
1 |
75,466,145 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5081:Obsl1
|
UTSW |
1 |
75,464,607 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R5389:Obsl1
|
UTSW |
1 |
75,479,905 (GRCm39) |
intron |
probably benign |
|
|
R5757:Obsl1
|
UTSW |
1 |
75,469,699 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5890:Obsl1
|
UTSW |
1 |
75,470,503 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5946:Obsl1
|
UTSW |
1 |
75,467,851 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6005:Obsl1
|
UTSW |
1 |
75,468,859 (GRCm39) |
splice site |
probably null |
|
|
R6118:Obsl1
|
UTSW |
1 |
75,468,722 (GRCm39) |
intron |
probably benign |
|
|
R6154:Obsl1
|
UTSW |
1 |
75,476,788 (GRCm39) |
missense |
probably benign |
0.19 |
|
R6317:Obsl1
|
UTSW |
1 |
75,466,273 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R6379:Obsl1
|
UTSW |
1 |
75,479,787 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6387:Obsl1
|
UTSW |
1 |
75,468,006 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7084:Obsl1
|
UTSW |
1 |
75,464,394 (GRCm39) |
missense |
probably benign |
|
|
R7123:Obsl1
|
UTSW |
1 |
75,466,313 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7202:Obsl1
|
UTSW |
1 |
75,466,360 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7291:Obsl1
|
UTSW |
1 |
75,466,161 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7305:Obsl1
|
UTSW |
1 |
75,470,590 (GRCm39) |
nonsense |
probably null |
|
|
R7366:Obsl1
|
UTSW |
1 |
75,479,608 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7402:Obsl1
|
UTSW |
1 |
75,464,348 (GRCm39) |
missense |
probably benign |
|
|
R7474:Obsl1
|
UTSW |
1 |
75,474,828 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7611:Obsl1
|
UTSW |
1 |
75,482,024 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7672:Obsl1
|
UTSW |
1 |
75,469,365 (GRCm39) |
missense |
probably benign |
0.18 |
|
R7715:Obsl1
|
UTSW |
1 |
75,478,680 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7762:Obsl1
|
UTSW |
1 |
75,480,167 (GRCm39) |
missense |
probably benign |
|
|
R8005:Obsl1
|
UTSW |
1 |
75,482,096 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8012:Obsl1
|
UTSW |
1 |
75,469,317 (GRCm39) |
missense |
probably benign |
0.12 |
|
R8379:Obsl1
|
UTSW |
1 |
75,480,501 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8381:Obsl1
|
UTSW |
1 |
75,480,501 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8383:Obsl1
|
UTSW |
1 |
75,480,501 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8396:Obsl1
|
UTSW |
1 |
75,480,350 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8465:Obsl1
|
UTSW |
1 |
75,480,032 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8506:Obsl1
|
UTSW |
1 |
75,482,300 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8710:Obsl1
|
UTSW |
1 |
75,469,326 (GRCm39) |
missense |
probably benign |
|
|
R8877:Obsl1
|
UTSW |
1 |
75,473,167 (GRCm39) |
nonsense |
probably null |
|
|
R8903:Obsl1
|
UTSW |
1 |
75,463,917 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R8913:Obsl1
|
UTSW |
1 |
75,467,892 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8924:Obsl1
|
UTSW |
1 |
75,482,841 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8955:Obsl1
|
UTSW |
1 |
75,480,493 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9008:Obsl1
|
UTSW |
1 |
75,482,027 (GRCm39) |
missense |
probably benign |
|
|
R9121:Obsl1
|
UTSW |
1 |
75,482,636 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R9295:Obsl1
|
UTSW |
1 |
75,476,721 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9362:Obsl1
|
UTSW |
1 |
75,482,391 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9367:Obsl1
|
UTSW |
1 |
75,466,177 (GRCm39) |
missense |
probably benign |
0.18 |
|
R9459:Obsl1
|
UTSW |
1 |
75,474,884 (GRCm39) |
missense |
probably benign |
0.16 |
|
R9496:Obsl1
|
UTSW |
1 |
75,467,484 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9498:Obsl1
|
UTSW |
1 |
75,467,484 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9502:Obsl1
|
UTSW |
1 |
75,466,267 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9546:Obsl1
|
UTSW |
1 |
75,482,030 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9550:Obsl1
|
UTSW |
1 |
75,474,910 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9561:Obsl1
|
UTSW |
1 |
75,480,157 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R9687:Obsl1
|
UTSW |
1 |
75,479,670 (GRCm39) |
missense |
probably damaging |
1.00 |
|
V8831:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
X0061:Obsl1
|
UTSW |
1 |
75,463,412 (GRCm39) |
missense |
probably benign |
|
|
Z1088:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
Z1176:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
Z1177:Obsl1
|
UTSW |
1 |
75,467,656 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
Z1177:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
Z1177:Obsl1
|
UTSW |
1 |
75,480,436 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTTGAGCAGGAGCCTTCTG -3'
(R):5'- TTCCCTTCCAGAGACAGAGC -3'
Sequencing Primer
(F):5'- TGGCTCTAACCCCAGATTGG -3'
(R):5'- CAGAGCTGCTGTTCTTGCG -3'
|
| Posted On |
2022-07-18 |
Incidental Mutation