Incidental Mutation 'R1439:Obsl1'
| ID |
160819 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Obsl1
|
| Ensembl Gene |
ENSMUSG00000026211 |
| Gene Name |
obscurin-like 1 |
| Synonyms |
|
| MMRRC Submission |
039494-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.269)
|
| Stock # |
R1439 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
75462469-75483134 bp(-) (GRCm39) |
| Type of Mutation |
nonsense |
| DNA Base Change (assembly) |
C to A
at 75463428 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Stop codon
at position 1755
(E1755*)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000109197
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000050899]
[ENSMUST00000113567]
[ENSMUST00000113575]
[ENSMUST00000148980]
[ENSMUST00000187411]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000050899
|
| SMART Domains |
Protein: ENSMUSP00000057865
Gene: ENSMUSG00000051703
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF4203
|
40 |
236 |
7.2e-51 |
PFAM |
|
low complexity region
|
252 |
302 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000113567
AA Change: E1755*
|
| SMART Domains |
Protein: ENSMUSP00000109197
Gene: ENSMUSG00000026211
AA Change: E1755*
| Domain | Start | End | E-Value | Type |
|---|
|
IGc2
|
24 |
91 |
1.23e-12 |
SMART |
|
IGc2
|
140 |
216 |
2.33e-13 |
SMART |
|
IGc2
|
258 |
326 |
1.48e-6 |
SMART |
|
IG
|
347 |
427 |
9.49e-5 |
SMART |
|
IG
|
435 |
511 |
1.04e-1 |
SMART |
|
FN3
|
518 |
601 |
6.6e-2 |
SMART |
|
PDB:2E6Q|A
|
608 |
714 |
8e-57 |
PDB |
|
Blast:IG_like
|
622 |
711 |
3e-50 |
BLAST |
|
IG
|
723 |
804 |
3.79e-4 |
SMART |
|
IG
|
814 |
893 |
2.58e-6 |
SMART |
|
IGc2
|
911 |
977 |
1.12e-6 |
SMART |
|
IG
|
996 |
1075 |
1.27e-5 |
SMART |
|
IGc2
|
1094 |
1160 |
4.07e-4 |
SMART |
|
IGc2
|
1186 |
1252 |
9.49e-5 |
SMART |
|
IG
|
1274 |
1353 |
7.41e-7 |
SMART |
|
IG
|
1363 |
1444 |
1.15e-3 |
SMART |
|
IG
|
1454 |
1533 |
8.33e-1 |
SMART |
|
IGc2
|
1549 |
1615 |
8.72e-4 |
SMART |
|
IG
|
1633 |
1712 |
1e-3 |
SMART |
|
IG
|
1723 |
1802 |
3.82e-9 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113575
|
| SMART Domains |
Protein: ENSMUSP00000109205
Gene: ENSMUSG00000051703
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF4203
|
39 |
237 |
2.2e-59 |
PFAM |
|
low complexity region
|
252 |
302 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000132252
|
| SMART Domains |
Protein: ENSMUSP00000117420
Gene: ENSMUSG00000026211
| Domain | Start | End | E-Value | Type |
|---|
|
IG_like
|
1 |
59 |
2.8e-1 |
SMART |
|
IGc2
|
85 |
151 |
9.49e-5 |
SMART |
|
IG
|
175 |
254 |
2.64e-3 |
SMART |
|
IG
|
265 |
344 |
7.41e-7 |
SMART |
|
Blast:IG
|
354 |
417 |
4e-35 |
BLAST |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000145382
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000148980
|
| SMART Domains |
Protein: ENSMUSP00000116977
Gene: ENSMUSG00000051703
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
8 |
19 |
N/A |
INTRINSIC |
|
Pfam:DUF4203
|
119 |
150 |
6.6e-12 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000150293
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000156499
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000154636
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000156705
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000155084
|
| SMART Domains |
Protein: ENSMUSP00000114553
Gene: ENSMUSG00000026211
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1g1ca_
|
2 |
32 |
1e-3 |
SMART |
|
IGc2
|
64 |
132 |
1.48e-6 |
SMART |
|
IG
|
153 |
233 |
9.49e-5 |
SMART |
|
IG
|
241 |
317 |
1.04e-1 |
SMART |
|
FN3
|
324 |
407 |
6.6e-2 |
SMART |
|
PDB:2E6Q|A
|
414 |
520 |
4e-57 |
PDB |
|
Blast:IG_like
|
428 |
517 |
2e-50 |
BLAST |
|
IG
|
529 |
610 |
3.79e-4 |
SMART |
|
IG
|
620 |
699 |
2.58e-6 |
SMART |
|
IGc2
|
717 |
783 |
1.12e-6 |
SMART |
|
IG
|
802 |
881 |
1.27e-5 |
SMART |
|
IGc2
|
900 |
966 |
4.07e-4 |
SMART |
|
IGc2
|
992 |
1058 |
9.49e-5 |
SMART |
|
IG
|
1080 |
1159 |
7.41e-7 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000187411
|
| SMART Domains |
Protein: ENSMUSP00000140795
Gene: ENSMUSG00000051703
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
38 |
50 |
N/A |
INTRINSIC |
|
Pfam:DUF4203
|
101 |
142 |
6.9e-10 |
PFAM |
|
| Meta Mutation Damage Score |
0.9755 |
| Coding Region Coverage |
- 1x: 98.8%
- 3x: 97.8%
- 10x: 94.4%
- 20x: 86.3%
|
| Validation Efficiency |
100% (72/72) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 70 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Agap1 |
A |
G |
1: 89,770,908 (GRCm39) |
N499S |
probably damaging |
Het |
| AI661453 |
C |
A |
17: 47,777,587 (GRCm39) |
|
probably benign |
Het |
| Akap1 |
C |
A |
11: 88,735,577 (GRCm39) |
G362* |
probably null |
Het |
| Alkbh1 |
A |
G |
12: 87,475,915 (GRCm39) |
V289A |
probably damaging |
Het |
| Bnc2 |
C |
T |
4: 84,194,305 (GRCm39) |
E1035K |
probably benign |
Het |
| C1s2 |
T |
A |
6: 124,607,126 (GRCm39) |
|
probably benign |
Het |
| Cabin1 |
A |
G |
10: 75,492,640 (GRCm39) |
I1885T |
probably damaging |
Het |
| Col22a1 |
A |
G |
15: 71,824,226 (GRCm39) |
|
probably benign |
Het |
| Cpne4 |
A |
T |
9: 104,866,831 (GRCm39) |
T248S |
probably damaging |
Het |
| Cracd |
T |
C |
5: 76,988,757 (GRCm39) |
V36A |
probably damaging |
Het |
| Cubn |
T |
C |
2: 13,292,379 (GRCm39) |
N3268S |
probably damaging |
Het |
| Ddx10 |
T |
A |
9: 53,151,787 (GRCm39) |
K79N |
probably damaging |
Het |
| Dennd1a |
A |
C |
2: 37,933,412 (GRCm39) |
L131R |
probably damaging |
Het |
| Dnah9 |
T |
C |
11: 65,764,958 (GRCm39) |
Y3862C |
probably benign |
Het |
| Eif3e |
A |
G |
15: 43,141,824 (GRCm39) |
|
probably benign |
Het |
| Emsy |
T |
C |
7: 98,250,048 (GRCm39) |
|
probably benign |
Het |
| Ep400 |
A |
T |
5: 110,833,344 (GRCm39) |
D1959E |
unknown |
Het |
| Fpr-rs7 |
A |
G |
17: 20,333,869 (GRCm39) |
I207T |
probably benign |
Het |
| Fubp3 |
C |
A |
2: 31,488,563 (GRCm39) |
L140I |
probably damaging |
Het |
| Gas2l2 |
T |
C |
11: 83,318,298 (GRCm39) |
D137G |
probably damaging |
Het |
| Git1 |
G |
T |
11: 77,397,244 (GRCm39) |
R699L |
possibly damaging |
Het |
| Gnao1 |
T |
A |
8: 94,690,065 (GRCm39) |
F27L |
probably benign |
Het |
| Hlx |
G |
T |
1: 184,464,184 (GRCm39) |
A52D |
probably damaging |
Het |
| Itga6 |
T |
G |
2: 71,664,378 (GRCm39) |
Y505D |
probably damaging |
Het |
| Itgad |
A |
T |
7: 127,782,178 (GRCm39) |
T205S |
probably benign |
Het |
| Jakmip3 |
A |
T |
7: 138,631,375 (GRCm39) |
Y574F |
probably benign |
Het |
| Laptm5 |
G |
T |
4: 130,653,520 (GRCm39) |
|
probably benign |
Het |
| Mlana |
A |
T |
19: 29,684,252 (GRCm39) |
R71S |
probably benign |
Het |
| Mroh2a |
G |
C |
1: 88,185,524 (GRCm39) |
E1510D |
probably damaging |
Het |
| Mus81 |
G |
C |
19: 5,535,145 (GRCm39) |
R295G |
probably benign |
Het |
| Ncapd3 |
T |
A |
9: 26,998,862 (GRCm39) |
|
probably null |
Het |
| Nectin1 |
A |
G |
9: 43,703,396 (GRCm39) |
E218G |
possibly damaging |
Het |
| Nectin3 |
A |
T |
16: 46,268,757 (GRCm39) |
Y548* |
probably null |
Het |
| Nif3l1 |
T |
C |
1: 58,487,102 (GRCm39) |
F96S |
probably damaging |
Het |
| Ntrk1 |
A |
G |
3: 87,696,918 (GRCm39) |
|
probably null |
Het |
| Or4p23 |
T |
C |
2: 88,577,178 (GRCm39) |
E18G |
possibly damaging |
Het |
| Osbpl9 |
T |
C |
4: 108,958,353 (GRCm39) |
D74G |
probably damaging |
Het |
| Osgin1 |
T |
A |
8: 120,169,852 (GRCm39) |
|
probably null |
Het |
| Otogl |
A |
G |
10: 107,615,113 (GRCm39) |
Y1931H |
probably benign |
Het |
| Pmepa1 |
A |
G |
2: 173,069,874 (GRCm39) |
I227T |
probably benign |
Het |
| Pprc1 |
T |
A |
19: 46,052,175 (GRCm39) |
N564K |
possibly damaging |
Het |
| Prkaa1 |
T |
C |
15: 5,194,225 (GRCm39) |
F92S |
probably damaging |
Het |
| Ptprd |
A |
G |
4: 75,984,437 (GRCm39) |
F811L |
probably damaging |
Het |
| Rad54b |
A |
G |
4: 11,606,152 (GRCm39) |
K520R |
possibly damaging |
Het |
| Rbfox1 |
A |
G |
16: 7,148,297 (GRCm39) |
T269A |
possibly damaging |
Het |
| Rfwd3 |
T |
C |
8: 112,004,920 (GRCm39) |
Y554C |
probably damaging |
Het |
| Rfx2 |
A |
T |
17: 57,094,720 (GRCm39) |
V208E |
probably damaging |
Het |
| Rgs22 |
G |
T |
15: 36,025,939 (GRCm39) |
|
probably benign |
Het |
| Rrbp1 |
A |
G |
2: 143,797,032 (GRCm39) |
|
probably null |
Het |
| Ryr2 |
C |
T |
13: 11,729,389 (GRCm39) |
|
probably benign |
Het |
| Sbno1 |
A |
G |
5: 124,522,523 (GRCm39) |
|
probably benign |
Het |
| Secisbp2 |
T |
C |
13: 51,833,759 (GRCm39) |
|
probably benign |
Het |
| Sgsm2 |
C |
A |
11: 74,759,964 (GRCm39) |
R58L |
probably benign |
Het |
| Slc25a36 |
A |
C |
9: 96,975,126 (GRCm39) |
|
probably benign |
Het |
| Spink4 |
A |
G |
4: 40,929,121 (GRCm39) |
T49A |
possibly damaging |
Het |
| Steap3 |
A |
T |
1: 120,155,550 (GRCm39) |
F470I |
probably damaging |
Het |
| Stk10 |
A |
G |
11: 32,567,919 (GRCm39) |
Q907R |
probably damaging |
Het |
| Tdrd5 |
A |
G |
1: 156,105,057 (GRCm39) |
V446A |
probably damaging |
Het |
| Tmem117 |
G |
A |
15: 94,992,478 (GRCm39) |
M379I |
probably benign |
Het |
| Trappc12 |
A |
G |
12: 28,797,160 (GRCm39) |
L124P |
possibly damaging |
Het |
| Trim9 |
G |
A |
12: 70,297,867 (GRCm39) |
H613Y |
probably damaging |
Het |
| Trio |
A |
G |
15: 27,898,000 (GRCm39) |
W371R |
probably damaging |
Het |
| Ulk4 |
G |
C |
9: 121,095,324 (GRCm39) |
H110D |
possibly damaging |
Het |
| Upb1 |
T |
C |
10: 75,275,776 (GRCm39) |
V387A |
probably benign |
Het |
| Utrn |
A |
T |
10: 12,619,793 (GRCm39) |
I284N |
possibly damaging |
Het |
| Vmn2r111 |
C |
A |
17: 22,790,097 (GRCm39) |
W303L |
probably benign |
Het |
| Vmn2r15 |
G |
T |
5: 109,441,953 (GRCm39) |
P160Q |
probably damaging |
Het |
| Wdtc1 |
A |
G |
4: 133,029,118 (GRCm39) |
S323P |
probably benign |
Het |
| Zfp846 |
T |
A |
9: 20,505,393 (GRCm39) |
C418S |
possibly damaging |
Het |
| Zfyve26 |
G |
T |
12: 79,298,937 (GRCm39) |
P441Q |
probably benign |
Het |
|
| Other mutations in Obsl1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00504:Obsl1
|
APN |
1 |
75,467,518 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01111:Obsl1
|
APN |
1 |
75,473,789 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
IGL01140:Obsl1
|
APN |
1 |
75,466,400 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02149:Obsl1
|
APN |
1 |
75,480,464 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02225:Obsl1
|
APN |
1 |
75,480,442 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02269:Obsl1
|
APN |
1 |
75,464,357 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02296:Obsl1
|
APN |
1 |
75,474,793 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL02386:Obsl1
|
APN |
1 |
75,469,161 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02408:Obsl1
|
APN |
1 |
75,481,890 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02601:Obsl1
|
APN |
1 |
75,466,264 (GRCm39) |
missense |
probably benign |
|
|
IGL03053:Obsl1
|
APN |
1 |
75,469,723 (GRCm39) |
missense |
probably benign |
|
|
IGL03181:Obsl1
|
APN |
1 |
75,469,228 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03402:Obsl1
|
APN |
1 |
75,463,443 (GRCm39) |
missense |
probably benign |
0.00 |
|
Jude
|
UTSW |
1 |
75,474,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT1430001:Obsl1
|
UTSW |
1 |
75,482,811 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4382001:Obsl1
|
UTSW |
1 |
75,464,607 (GRCm39) |
missense |
probably benign |
0.06 |
|
R0281:Obsl1
|
UTSW |
1 |
75,469,571 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1343:Obsl1
|
UTSW |
1 |
75,469,223 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1394:Obsl1
|
UTSW |
1 |
75,469,309 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1395:Obsl1
|
UTSW |
1 |
75,469,309 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1456:Obsl1
|
UTSW |
1 |
75,464,300 (GRCm39) |
nonsense |
probably null |
|
|
R1728:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1729:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1730:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1739:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1757:Obsl1
|
UTSW |
1 |
75,470,527 (GRCm39) |
missense |
probably benign |
|
|
R1762:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1783:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1784:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1785:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R1851:Obsl1
|
UTSW |
1 |
75,469,537 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1864:Obsl1
|
UTSW |
1 |
75,469,753 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1873:Obsl1
|
UTSW |
1 |
75,474,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1875:Obsl1
|
UTSW |
1 |
75,474,877 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1980:Obsl1
|
UTSW |
1 |
75,482,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1985:Obsl1
|
UTSW |
1 |
75,482,244 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2049:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R2069:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R2122:Obsl1
|
UTSW |
1 |
75,470,527 (GRCm39) |
missense |
probably benign |
|
|
R2141:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R2142:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
R2184:Obsl1
|
UTSW |
1 |
75,478,861 (GRCm39) |
missense |
probably benign |
0.26 |
|
R2267:Obsl1
|
UTSW |
1 |
75,482,342 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2883:Obsl1
|
UTSW |
1 |
75,473,155 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R3079:Obsl1
|
UTSW |
1 |
75,467,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3749:Obsl1
|
UTSW |
1 |
75,474,890 (GRCm39) |
missense |
probably benign |
|
|
R4002:Obsl1
|
UTSW |
1 |
75,476,743 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R4365:Obsl1
|
UTSW |
1 |
75,464,693 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R4366:Obsl1
|
UTSW |
1 |
75,464,693 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R4414:Obsl1
|
UTSW |
1 |
75,467,546 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4700:Obsl1
|
UTSW |
1 |
75,480,085 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4799:Obsl1
|
UTSW |
1 |
75,466,145 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5081:Obsl1
|
UTSW |
1 |
75,464,607 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R5389:Obsl1
|
UTSW |
1 |
75,479,905 (GRCm39) |
intron |
probably benign |
|
|
R5757:Obsl1
|
UTSW |
1 |
75,469,699 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5890:Obsl1
|
UTSW |
1 |
75,470,503 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5946:Obsl1
|
UTSW |
1 |
75,467,851 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6005:Obsl1
|
UTSW |
1 |
75,468,859 (GRCm39) |
splice site |
probably null |
|
|
R6118:Obsl1
|
UTSW |
1 |
75,468,722 (GRCm39) |
intron |
probably benign |
|
|
R6154:Obsl1
|
UTSW |
1 |
75,476,788 (GRCm39) |
missense |
probably benign |
0.19 |
|
R6317:Obsl1
|
UTSW |
1 |
75,466,273 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R6379:Obsl1
|
UTSW |
1 |
75,479,787 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6387:Obsl1
|
UTSW |
1 |
75,468,006 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7084:Obsl1
|
UTSW |
1 |
75,464,394 (GRCm39) |
missense |
probably benign |
|
|
R7123:Obsl1
|
UTSW |
1 |
75,466,313 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7202:Obsl1
|
UTSW |
1 |
75,466,360 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7291:Obsl1
|
UTSW |
1 |
75,466,161 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7305:Obsl1
|
UTSW |
1 |
75,470,590 (GRCm39) |
nonsense |
probably null |
|
|
R7366:Obsl1
|
UTSW |
1 |
75,479,608 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7402:Obsl1
|
UTSW |
1 |
75,464,348 (GRCm39) |
missense |
probably benign |
|
|
R7474:Obsl1
|
UTSW |
1 |
75,474,828 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7611:Obsl1
|
UTSW |
1 |
75,482,024 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7672:Obsl1
|
UTSW |
1 |
75,469,365 (GRCm39) |
missense |
probably benign |
0.18 |
|
R7715:Obsl1
|
UTSW |
1 |
75,478,680 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7762:Obsl1
|
UTSW |
1 |
75,480,167 (GRCm39) |
missense |
probably benign |
|
|
R8005:Obsl1
|
UTSW |
1 |
75,482,096 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8012:Obsl1
|
UTSW |
1 |
75,469,317 (GRCm39) |
missense |
probably benign |
0.12 |
|
R8379:Obsl1
|
UTSW |
1 |
75,480,501 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8381:Obsl1
|
UTSW |
1 |
75,480,501 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8383:Obsl1
|
UTSW |
1 |
75,480,501 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8396:Obsl1
|
UTSW |
1 |
75,480,350 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8465:Obsl1
|
UTSW |
1 |
75,480,032 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8506:Obsl1
|
UTSW |
1 |
75,482,300 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8710:Obsl1
|
UTSW |
1 |
75,469,326 (GRCm39) |
missense |
probably benign |
|
|
R8877:Obsl1
|
UTSW |
1 |
75,473,167 (GRCm39) |
nonsense |
probably null |
|
|
R8903:Obsl1
|
UTSW |
1 |
75,463,917 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R8913:Obsl1
|
UTSW |
1 |
75,467,892 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8924:Obsl1
|
UTSW |
1 |
75,482,841 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8955:Obsl1
|
UTSW |
1 |
75,480,493 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9008:Obsl1
|
UTSW |
1 |
75,482,027 (GRCm39) |
missense |
probably benign |
|
|
R9121:Obsl1
|
UTSW |
1 |
75,482,636 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R9295:Obsl1
|
UTSW |
1 |
75,476,721 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9362:Obsl1
|
UTSW |
1 |
75,482,391 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9367:Obsl1
|
UTSW |
1 |
75,466,177 (GRCm39) |
missense |
probably benign |
0.18 |
|
R9459:Obsl1
|
UTSW |
1 |
75,474,884 (GRCm39) |
missense |
probably benign |
0.16 |
|
R9496:Obsl1
|
UTSW |
1 |
75,467,484 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9497:Obsl1
|
UTSW |
1 |
75,467,484 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9498:Obsl1
|
UTSW |
1 |
75,467,484 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9502:Obsl1
|
UTSW |
1 |
75,466,267 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9546:Obsl1
|
UTSW |
1 |
75,482,030 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9550:Obsl1
|
UTSW |
1 |
75,474,910 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9561:Obsl1
|
UTSW |
1 |
75,480,157 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R9687:Obsl1
|
UTSW |
1 |
75,479,670 (GRCm39) |
missense |
probably damaging |
1.00 |
|
V8831:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
X0061:Obsl1
|
UTSW |
1 |
75,463,412 (GRCm39) |
missense |
probably benign |
|
|
Z1088:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
Z1176:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
Z1177:Obsl1
|
UTSW |
1 |
75,467,656 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
Z1177:Obsl1
|
UTSW |
1 |
75,486,756 (GRCm38) |
missense |
probably benign |
|
|
Z1177:Obsl1
|
UTSW |
1 |
75,480,436 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CAACCTTGAGTGTGATCTCTCCCG -3'
(R):5'- GTGCGTGTCCTTATTAAGCCCCTG -3'
Sequencing Primer
(F):5'- CATAGGTATAGCTCGGCACTG -3'
(R):5'- ATTAAGCCCCTGTCCCCC -3'
|
| Posted On |
2014-03-14 |
Incidental Mutation