Incidental Mutation 'R9710:Myocd'
| ID |
730089 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myocd
|
| Ensembl Gene |
ENSMUSG00000020542 |
| Gene Name |
myocardin |
| Synonyms |
Srfcp |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R9710 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
11 |
| Chromosomal Location |
65067387-65160815 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 65087167 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Lysine to Asparagine
at position 253
(K253N)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000104335
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000101042]
[ENSMUST00000102635]
[ENSMUST00000108695]
|
| AlphaFold |
Q8VIM5 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000101042
AA Change: K125N
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000098603
Gene: ENSMUSG00000020542
AA Change: K125N
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
19 |
32 |
N/A |
INTRINSIC |
|
low complexity region
|
119 |
132 |
N/A |
INTRINSIC |
|
SCOP:d1lsha3
|
140 |
221 |
4e-3 |
SMART |
|
SAP
|
252 |
286 |
1.29e-8 |
SMART |
|
low complexity region
|
326 |
343 |
N/A |
INTRINSIC |
|
low complexity region
|
371 |
383 |
N/A |
INTRINSIC |
|
coiled coil region
|
396 |
435 |
N/A |
INTRINSIC |
|
low complexity region
|
557 |
573 |
N/A |
INTRINSIC |
|
low complexity region
|
615 |
629 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000102635
AA Change: K253N
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000099695
Gene: ENSMUSG00000020542
AA Change: K253N
| Domain | Start | End | E-Value | Type |
|---|
|
RPEL
|
18 |
43 |
4e-1 |
SMART |
|
RPEL
|
62 |
87 |
9.26e0 |
SMART |
|
RPEL
|
106 |
131 |
1.15e-6 |
SMART |
|
low complexity region
|
147 |
160 |
N/A |
INTRINSIC |
|
low complexity region
|
247 |
260 |
N/A |
INTRINSIC |
|
SCOP:d1lsha3
|
268 |
349 |
4e-3 |
SMART |
|
SAP
|
380 |
414 |
1.29e-8 |
SMART |
|
low complexity region
|
454 |
471 |
N/A |
INTRINSIC |
|
low complexity region
|
499 |
511 |
N/A |
INTRINSIC |
|
coiled coil region
|
524 |
563 |
N/A |
INTRINSIC |
|
low complexity region
|
695 |
709 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000108695
AA Change: K253N
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000104335
Gene: ENSMUSG00000020542
AA Change: K253N
| Domain | Start | End | E-Value | Type |
|---|
|
RPEL
|
18 |
43 |
4e-1 |
SMART |
|
RPEL
|
62 |
87 |
9.26e0 |
SMART |
|
RPEL
|
106 |
131 |
1.15e-6 |
SMART |
|
low complexity region
|
147 |
160 |
N/A |
INTRINSIC |
|
low complexity region
|
247 |
260 |
N/A |
INTRINSIC |
|
SCOP:d1lsha3
|
268 |
349 |
5e-3 |
SMART |
|
SAP
|
380 |
414 |
1.29e-8 |
SMART |
|
low complexity region
|
454 |
471 |
N/A |
INTRINSIC |
|
low complexity region
|
499 |
511 |
N/A |
INTRINSIC |
|
coiled coil region
|
524 |
563 |
N/A |
INTRINSIC |
|
low complexity region
|
685 |
701 |
N/A |
INTRINSIC |
|
low complexity region
|
743 |
757 |
N/A |
INTRINSIC |
|
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000115572
Gene: ENSMUSG00000020542
AA Change: K127N
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
22 |
35 |
N/A |
INTRINSIC |
|
low complexity region
|
122 |
135 |
N/A |
INTRINSIC |
|
low complexity region
|
160 |
195 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.7%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a nuclear protein, which is expressed in heart, aorta, and in smooth muscle cell-containing tissues. It functions as a transcriptional co-activator of serum response factor (SRF) and modulates expression of cardiac and smooth muscle-specific SRF-target genes, and thus may play a crucial role in cardiogenesis and differentiation of the smooth muscle cell lineage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
PHENOTYPE: Mice homozygous for a null mutation exhibit embryonic lethality and fail to form vascular smooth muscle. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 92 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930407I10Rik |
T |
C |
15: 81,946,852 (GRCm39) |
S250P |
probably benign |
Het |
| Ahcyl1 |
T |
A |
3: 107,578,494 (GRCm39) |
I248F |
possibly damaging |
Het |
| Alpk2 |
T |
A |
18: 65,482,646 (GRCm39) |
E454V |
probably damaging |
Het |
| Ank3 |
A |
T |
10: 69,829,070 (GRCm39) |
T2580S |
|
Het |
| Anks1 |
G |
A |
17: 28,128,571 (GRCm39) |
G46R |
possibly damaging |
Het |
| Arhgap45 |
A |
G |
10: 79,857,635 (GRCm39) |
E322G |
probably damaging |
Het |
| Arhgef2 |
T |
C |
3: 88,528,576 (GRCm39) |
I4T |
probably benign |
Het |
| C1qtnf4 |
T |
C |
2: 90,720,351 (GRCm39) |
I208T |
probably damaging |
Het |
| Cachd1 |
T |
A |
4: 100,832,092 (GRCm39) |
N751K |
probably benign |
Het |
| Cacna1a |
G |
T |
8: 85,320,808 (GRCm39) |
V1589F |
possibly damaging |
Het |
| Cacnb1 |
T |
C |
11: 97,902,197 (GRCm39) |
H205R |
probably benign |
Het |
| Castor1 |
A |
G |
11: 4,169,015 (GRCm39) |
K61E |
probably benign |
Het |
| Ccdc9b |
G |
T |
2: 118,591,077 (GRCm39) |
A152E |
probably benign |
Het |
| Clvs2 |
C |
A |
10: 33,389,307 (GRCm39) |
R311L |
probably benign |
Het |
| Crim1 |
G |
T |
17: 78,610,504 (GRCm39) |
G320* |
probably null |
Het |
| Crtam |
A |
T |
9: 40,895,671 (GRCm39) |
D218E |
probably benign |
Het |
| Cwc27 |
G |
A |
13: 104,943,158 (GRCm39) |
T128I |
probably damaging |
Het |
| Cyp4a14 |
T |
A |
4: 115,349,347 (GRCm39) |
I238F |
probably benign |
Het |
| D930020B18Rik |
A |
C |
10: 121,503,563 (GRCm39) |
E246A |
probably benign |
Het |
| Dsg1c |
T |
A |
18: 20,410,044 (GRCm39) |
V504E |
probably benign |
Het |
| Enpp6 |
T |
A |
8: 47,518,948 (GRCm39) |
S239T |
probably damaging |
Het |
| Eri2 |
A |
T |
7: 119,384,824 (GRCm39) |
I559N |
probably benign |
Het |
| Fbxo34 |
T |
C |
14: 47,768,724 (GRCm39) |
Y746H |
probably damaging |
Het |
| Galr1 |
A |
T |
18: 82,424,103 (GRCm39) |
L58Q |
probably damaging |
Het |
| Ghdc |
A |
G |
11: 100,658,863 (GRCm39) |
V423A |
probably benign |
Het |
| Glt28d2 |
T |
C |
3: 85,779,059 (GRCm39) |
D138G |
probably benign |
Het |
| Gm266 |
A |
T |
12: 111,451,763 (GRCm39) |
C148S |
probably benign |
Het |
| Gnas |
C |
T |
2: 174,141,132 (GRCm39) |
T493M |
unknown |
Het |
| Hivep2 |
T |
C |
10: 14,015,203 (GRCm39) |
I1790T |
probably damaging |
Het |
| Impg1 |
A |
G |
9: 80,287,276 (GRCm39) |
V390A |
probably benign |
Het |
| Isy1 |
A |
G |
6: 87,796,574 (GRCm39) |
F239L |
possibly damaging |
Het |
| Itgb5 |
A |
G |
16: 33,685,917 (GRCm39) |
T86A |
probably benign |
Het |
| Itpr1 |
T |
C |
6: 108,382,481 (GRCm39) |
C1458R |
possibly damaging |
Het |
| Krt28 |
T |
C |
11: 99,255,921 (GRCm39) |
E446G |
probably damaging |
Het |
| Lama1 |
A |
T |
17: 68,129,404 (GRCm39) |
Q3071L |
|
Het |
| Lasp1 |
A |
G |
11: 97,697,593 (GRCm39) |
|
probably benign |
Het |
| Lmf2 |
T |
C |
15: 89,237,419 (GRCm39) |
K348E |
probably benign |
Het |
| Lrch3 |
G |
T |
16: 32,796,108 (GRCm39) |
E331* |
probably null |
Het |
| Lzic |
T |
A |
4: 149,573,141 (GRCm39) |
F98I |
probably damaging |
Het |
| Map7d1 |
C |
A |
4: 126,127,440 (GRCm39) |
|
probably null |
Het |
| Marchf8 |
C |
T |
6: 116,378,405 (GRCm39) |
T113I |
possibly damaging |
Het |
| Mgrn1 |
A |
T |
16: 4,745,740 (GRCm39) |
K423* |
probably null |
Het |
| Muc20 |
G |
A |
16: 32,615,266 (GRCm39) |
T37I |
possibly damaging |
Het |
| Myh15 |
A |
G |
16: 48,959,044 (GRCm39) |
E972G |
probably damaging |
Het |
| Myod1 |
T |
G |
7: 46,026,575 (GRCm39) |
L160R |
probably damaging |
Het |
| Nanog |
T |
C |
6: 122,684,799 (GRCm39) |
S20P |
probably benign |
Het |
| Nat8f2 |
A |
T |
6: 85,844,683 (GRCm39) |
Y226* |
probably null |
Het |
| Nsmf |
A |
G |
2: 24,949,077 (GRCm39) |
K277R |
probably null |
Het |
| Nsrp1 |
C |
T |
11: 76,967,503 (GRCm39) |
G30R |
probably damaging |
Het |
| Nsun6 |
C |
A |
2: 15,003,009 (GRCm39) |
R389L |
probably benign |
Het |
| Obscn |
G |
A |
11: 58,943,397 (GRCm39) |
R4251C |
probably benign |
Het |
| Or10g9 |
A |
T |
9: 39,912,172 (GRCm39) |
M117K |
probably damaging |
Het |
| Or11h4 |
C |
T |
14: 50,974,199 (GRCm39) |
C140Y |
probably benign |
Het |
| Or51h1 |
A |
G |
7: 102,308,441 (GRCm39) |
T138A |
probably damaging |
Het |
| Or5w20 |
G |
A |
2: 87,726,902 (GRCm39) |
D120N |
probably damaging |
Het |
| Pgm1 |
T |
C |
4: 99,843,918 (GRCm39) |
L567P |
probably damaging |
Het |
| Polrmt |
G |
T |
10: 79,576,535 (GRCm39) |
H474N |
probably benign |
Het |
| Ppfia2 |
A |
G |
10: 106,664,885 (GRCm39) |
I374V |
probably benign |
Het |
| Pramel5 |
T |
A |
4: 143,999,545 (GRCm39) |
I181F |
probably benign |
Het |
| Prpf4b |
T |
A |
13: 35,083,870 (GRCm39) |
Y880N |
probably damaging |
Het |
| Ptpn3 |
G |
A |
4: 57,249,957 (GRCm39) |
Q180* |
probably null |
Het |
| Ptprc |
T |
C |
1: 138,008,627 (GRCm39) |
R687G |
probably damaging |
Het |
| Rnaseh2a |
T |
C |
8: 85,684,638 (GRCm39) |
T241A |
probably damaging |
Het |
| Rnf148 |
T |
A |
6: 23,654,802 (GRCm39) |
I65F |
possibly damaging |
Het |
| Rnf213 |
A |
G |
11: 119,331,831 (GRCm39) |
I2348V |
|
Het |
| Rttn |
A |
G |
18: 89,035,334 (GRCm39) |
N736S |
possibly damaging |
Het |
| Ryr3 |
A |
C |
2: 112,633,534 (GRCm39) |
V2093G |
probably damaging |
Het |
| Selenof |
T |
A |
3: 144,283,370 (GRCm39) |
F33L |
probably benign |
Het |
| Sh2d3c |
C |
T |
2: 32,635,889 (GRCm39) |
R238* |
probably null |
Het |
| Slc23a4 |
T |
C |
6: 34,923,235 (GRCm39) |
K543R |
probably benign |
Het |
| Smn1 |
A |
T |
13: 100,272,210 (GRCm39) |
N278I |
possibly damaging |
Het |
| Sox7 |
G |
A |
14: 64,185,509 (GRCm39) |
A182T |
probably benign |
Het |
| Spata31e5 |
T |
A |
1: 28,817,120 (GRCm39) |
Y304F |
probably benign |
Het |
| Sptlc2 |
A |
T |
12: 87,359,533 (GRCm39) |
I501N |
probably benign |
Het |
| Srf |
T |
C |
17: 46,866,271 (GRCm39) |
T162A |
probably benign |
Het |
| Srm |
C |
T |
4: 148,676,039 (GRCm39) |
|
probably benign |
Het |
| Stim1 |
CAGCGCCTGACGGAGC |
CAGC |
7: 102,080,118 (GRCm39) |
|
probably benign |
Het |
| Taar8a |
T |
C |
10: 23,952,714 (GRCm39) |
L106P |
probably damaging |
Het |
| Tcte1 |
A |
G |
17: 45,850,798 (GRCm39) |
H358R |
possibly damaging |
Het |
| Tmem205 |
A |
G |
9: 21,837,587 (GRCm39) |
S20P |
probably damaging |
Het |
| Trav16 |
T |
A |
14: 53,980,910 (GRCm39) |
V33E |
possibly damaging |
Het |
| Trf |
T |
A |
9: 103,103,217 (GRCm39) |
I149F |
probably damaging |
Het |
| Trmt2a |
C |
T |
16: 18,070,041 (GRCm39) |
Q419* |
probably null |
Het |
| Ttc19 |
A |
G |
11: 62,203,997 (GRCm39) |
I319M |
probably benign |
Het |
| Txndc16 |
T |
C |
14: 45,400,467 (GRCm39) |
I345V |
probably benign |
Het |
| Ube3b |
T |
C |
5: 114,553,370 (GRCm39) |
I914T |
probably benign |
Het |
| Ubr3 |
T |
C |
2: 69,727,957 (GRCm39) |
F107L |
possibly damaging |
Het |
| Vmn1r73 |
T |
C |
7: 11,490,407 (GRCm39) |
F75S |
possibly damaging |
Het |
| Vmn2r54 |
A |
T |
7: 12,363,753 (GRCm39) |
M380K |
possibly damaging |
Het |
| Wdr7 |
T |
A |
18: 63,927,317 (GRCm39) |
M989K |
possibly damaging |
Het |
| Zcchc3 |
A |
G |
2: 152,256,385 (GRCm39) |
S105P |
probably benign |
Het |
| Zfp735 |
T |
A |
11: 73,601,806 (GRCm39) |
V250E |
possibly damaging |
Het |
|
| Other mutations in Myocd |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00092:Myocd
|
APN |
11 |
65,071,770 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL00481:Myocd
|
APN |
11 |
65,077,980 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00857:Myocd
|
APN |
11 |
65,069,662 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL01012:Myocd
|
APN |
11 |
65,075,451 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
IGL01570:Myocd
|
APN |
11 |
65,091,633 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01865:Myocd
|
APN |
11 |
65,091,723 (GRCm39) |
missense |
probably benign |
0.30 |
|
IGL01938:Myocd
|
APN |
11 |
65,077,914 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02324:Myocd
|
APN |
11 |
65,069,484 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02598:Myocd
|
APN |
11 |
65,074,296 (GRCm39) |
missense |
probably benign |
0.31 |
|
IGL02886:Myocd
|
APN |
11 |
65,069,569 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03008:Myocd
|
APN |
11 |
65,078,392 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL03034:Myocd
|
APN |
11 |
65,109,511 (GRCm39) |
missense |
probably benign |
0.00 |
|
harvey
|
UTSW |
11 |
65,069,856 (GRCm39) |
splice site |
probably null |
|
|
irma
|
UTSW |
11 |
65,087,220 (GRCm39) |
missense |
probably benign |
0.02 |
|
myra
|
UTSW |
11 |
65,069,685 (GRCm39) |
missense |
probably benign |
0.10 |
|
Nate
|
UTSW |
11 |
65,123,914 (GRCm39) |
splice site |
probably null |
|
|
R0838_Myocd_053
|
UTSW |
11 |
65,069,758 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0078:Myocd
|
UTSW |
11 |
65,078,290 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R0097:Myocd
|
UTSW |
11 |
65,069,840 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R0097:Myocd
|
UTSW |
11 |
65,069,840 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R0234:Myocd
|
UTSW |
11 |
65,078,066 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0234:Myocd
|
UTSW |
11 |
65,078,066 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0453:Myocd
|
UTSW |
11 |
65,087,051 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0523:Myocd
|
UTSW |
11 |
65,071,728 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0838:Myocd
|
UTSW |
11 |
65,069,758 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0899:Myocd
|
UTSW |
11 |
65,086,018 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R1167:Myocd
|
UTSW |
11 |
65,087,203 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R1472:Myocd
|
UTSW |
11 |
65,078,330 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1508:Myocd
|
UTSW |
11 |
65,075,342 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1620:Myocd
|
UTSW |
11 |
65,087,220 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1630:Myocd
|
UTSW |
11 |
65,087,220 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1731:Myocd
|
UTSW |
11 |
65,091,714 (GRCm39) |
missense |
probably benign |
0.30 |
|
R1740:Myocd
|
UTSW |
11 |
65,109,347 (GRCm39) |
splice site |
probably benign |
|
|
R1769:Myocd
|
UTSW |
11 |
65,069,527 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1823:Myocd
|
UTSW |
11 |
65,069,496 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1968:Myocd
|
UTSW |
11 |
65,091,733 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1997:Myocd
|
UTSW |
11 |
65,095,147 (GRCm39) |
nonsense |
probably null |
|
|
R2018:Myocd
|
UTSW |
11 |
65,077,854 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2105:Myocd
|
UTSW |
11 |
65,109,484 (GRCm39) |
nonsense |
probably null |
|
|
R2314:Myocd
|
UTSW |
11 |
65,091,633 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4330:Myocd
|
UTSW |
11 |
65,114,590 (GRCm39) |
missense |
probably benign |
0.12 |
|
R4331:Myocd
|
UTSW |
11 |
65,114,590 (GRCm39) |
missense |
probably benign |
0.12 |
|
R4603:Myocd
|
UTSW |
11 |
65,078,571 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R4619:Myocd
|
UTSW |
11 |
65,069,254 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R4631:Myocd
|
UTSW |
11 |
65,069,685 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4865:Myocd
|
UTSW |
11 |
65,069,856 (GRCm39) |
splice site |
probably null |
|
|
R4974:Myocd
|
UTSW |
11 |
65,074,299 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R4976:Myocd
|
UTSW |
11 |
65,112,876 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5478:Myocd
|
UTSW |
11 |
65,123,914 (GRCm39) |
splice site |
probably null |
|
|
R5499:Myocd
|
UTSW |
11 |
65,069,575 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R6052:Myocd
|
UTSW |
11 |
65,087,082 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6356:Myocd
|
UTSW |
11 |
65,109,396 (GRCm39) |
splice site |
probably null |
|
|
R7144:Myocd
|
UTSW |
11 |
65,109,474 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7261:Myocd
|
UTSW |
11 |
65,078,422 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7354:Myocd
|
UTSW |
11 |
65,078,319 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7461:Myocd
|
UTSW |
11 |
65,109,429 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7613:Myocd
|
UTSW |
11 |
65,109,429 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7718:Myocd
|
UTSW |
11 |
65,109,452 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7956:Myocd
|
UTSW |
11 |
65,160,494 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R8345:Myocd
|
UTSW |
11 |
65,077,958 (GRCm39) |
nonsense |
probably null |
|
|
R8975:Myocd
|
UTSW |
11 |
65,069,287 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9051:Myocd
|
UTSW |
11 |
65,077,795 (GRCm39) |
missense |
probably benign |
|
|
R9400:Myocd
|
UTSW |
11 |
65,086,934 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9469:Myocd
|
UTSW |
11 |
65,087,220 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9565:Myocd
|
UTSW |
11 |
65,078,209 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9567:Myocd
|
UTSW |
11 |
65,078,410 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9585:Myocd
|
UTSW |
11 |
65,095,192 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9768:Myocd
|
UTSW |
11 |
65,078,217 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0057:Myocd
|
UTSW |
11 |
65,074,271 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
Z1186:Myocd
|
UTSW |
11 |
65,075,418 (GRCm39) |
missense |
probably benign |
|
|
Z1187:Myocd
|
UTSW |
11 |
65,075,418 (GRCm39) |
missense |
probably benign |
|
|
Z1188:Myocd
|
UTSW |
11 |
65,075,418 (GRCm39) |
missense |
probably benign |
|
|
Z1189:Myocd
|
UTSW |
11 |
65,075,418 (GRCm39) |
missense |
probably benign |
|
|
Z1190:Myocd
|
UTSW |
11 |
65,075,418 (GRCm39) |
missense |
probably benign |
|
|
Z1191:Myocd
|
UTSW |
11 |
65,075,418 (GRCm39) |
missense |
probably benign |
|
|
Z1192:Myocd
|
UTSW |
11 |
65,075,418 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TTTGGTGCATCCCAGGGTAG -3'
(R):5'- GTGTAAGGTGCCTATGTGCC -3'
Sequencing Primer
(F):5'- TGCATCCCAGGGTAGCTGAAC -3'
(R):5'- AAGGTGCCTATGTGCCGTGAG -3'
|
| Posted On |
2022-10-06 |
Incidental Mutation