Incidental Mutation 'R9694:Osbpl1a'
| ID |
735990 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Osbpl1a
|
| Ensembl Gene |
ENSMUSG00000044252 |
| Gene Name |
oxysterol binding protein-like 1A |
| Synonyms |
G430090F17Rik, LOC328902 |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.108)
|
| Stock # |
R9694 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
18 |
| Chromosomal Location |
12888371-13074898 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 12952565 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Histidine to Arginine
at position 533
(H533R)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000073957
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000074352]
[ENSMUST00000117361]
[ENSMUST00000118313]
[ENSMUST00000119043]
[ENSMUST00000119512]
[ENSMUST00000121774]
[ENSMUST00000121808]
[ENSMUST00000121888]
[ENSMUST00000124570]
[ENSMUST00000143077]
[ENSMUST00000155650]
|
| AlphaFold |
Q91XL9 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000074352
AA Change: H533R
PolyPhen 2
Score 0.031 (Sensitivity: 0.95; Specificity: 0.82)
|
| SMART Domains |
Protein: ENSMUSP00000073957
Gene: ENSMUSG00000044252
AA Change: H533R
| Domain | Start | End | E-Value | Type |
|---|
|
ANK
|
47 |
76 |
2.05e-6 |
SMART |
|
ANK
|
80 |
109 |
1.29e-3 |
SMART |
|
low complexity region
|
141 |
153 |
N/A |
INTRINSIC |
|
ANK
|
175 |
204 |
1.31e-4 |
SMART |
|
PH
|
236 |
336 |
6.02e-8 |
SMART |
|
low complexity region
|
345 |
354 |
N/A |
INTRINSIC |
|
coiled coil region
|
430 |
463 |
N/A |
INTRINSIC |
|
Pfam:Oxysterol_BP
|
548 |
940 |
6.7e-149 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000117361
AA Change: H20R
PolyPhen 2
Score 0.031 (Sensitivity: 0.95; Specificity: 0.82)
|
| SMART Domains |
Protein: ENSMUSP00000112681
Gene: ENSMUSG00000044252
AA Change: H20R
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Oxysterol_BP
|
35 |
428 |
5.1e-150 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000118313
AA Change: H20R
PolyPhen 2
Score 0.031 (Sensitivity: 0.95; Specificity: 0.82)
|
| SMART Domains |
Protein: ENSMUSP00000113735
Gene: ENSMUSG00000044252
AA Change: H20R
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Oxysterol_BP
|
35 |
428 |
5.1e-150 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000119043
AA Change: H20R
PolyPhen 2
Score 0.031 (Sensitivity: 0.95; Specificity: 0.82)
|
| SMART Domains |
Protein: ENSMUSP00000113357
Gene: ENSMUSG00000044252
AA Change: H20R
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Oxysterol_BP
|
35 |
428 |
5.1e-150 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000119512
AA Change: H141R
PolyPhen 2
Score 0.031 (Sensitivity: 0.95; Specificity: 0.82)
|
| SMART Domains |
Protein: ENSMUSP00000113914
Gene: ENSMUSG00000044252
AA Change: H141R
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
38 |
71 |
N/A |
INTRINSIC |
|
Pfam:Oxysterol_BP
|
156 |
549 |
1.2e-149 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000121774
|
| SMART Domains |
Protein: ENSMUSP00000113268
Gene: ENSMUSG00000044252
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Oxysterol_BP
|
8 |
401 |
4e-150 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000121808
AA Change: H20R
PolyPhen 2
Score 0.031 (Sensitivity: 0.95; Specificity: 0.82)
|
| SMART Domains |
Protein: ENSMUSP00000113841
Gene: ENSMUSG00000044252
AA Change: H20R
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Oxysterol_BP
|
35 |
428 |
5.1e-150 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000121888
AA Change: H20R
PolyPhen 2
Score 0.031 (Sensitivity: 0.95; Specificity: 0.82)
|
| SMART Domains |
Protein: ENSMUSP00000112895
Gene: ENSMUSG00000044252
AA Change: H20R
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Oxysterol_BP
|
35 |
428 |
5.1e-150 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000124570
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000143077
AA Change: H20R
PolyPhen 2
Score 0.031 (Sensitivity: 0.95; Specificity: 0.82)
|
| SMART Domains |
Protein: ENSMUSP00000122967
Gene: ENSMUSG00000044252
AA Change: H20R
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Oxysterol_BP
|
35 |
184 |
3.5e-69 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000155650
AA Change: H116R
PolyPhen 2
Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000120439
Gene: ENSMUSG00000044252
AA Change: H116R
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
13 |
46 |
N/A |
INTRINSIC |
|
Pfam:Oxysterol_BP
|
131 |
187 |
1.3e-23 |
PFAM |
|
| Coding Region Coverage |
- 1x: 99.8%
- 3x: 99.7%
- 10x: 99.3%
- 20x: 98.7%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. Transcript variants derived from alternative promoter usage and/or alternative splicing exist; they encode different isoforms. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 77 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcb1b |
T |
A |
5: 8,899,573 (GRCm39) |
Y948N |
probably damaging |
Het |
| Adamts2 |
A |
G |
11: 50,558,972 (GRCm39) |
D229G |
probably benign |
Het |
| Adamts4 |
T |
C |
1: 171,081,530 (GRCm39) |
S395P |
probably benign |
Het |
| Adcy1 |
T |
C |
11: 7,094,774 (GRCm39) |
Y567H |
probably damaging |
Het |
| Agap3 |
A |
G |
5: 24,682,139 (GRCm39) |
N212D |
probably benign |
Het |
| Atp2a2 |
A |
G |
5: 122,597,708 (GRCm39) |
F775S |
probably damaging |
Het |
| Baz1b |
A |
T |
5: 135,273,094 (GRCm39) |
Q1406L |
probably benign |
Het |
| C030006K11Rik |
A |
T |
15: 76,607,928 (GRCm39) |
V30D |
possibly damaging |
Het |
| Cep170b |
T |
A |
12: 112,701,993 (GRCm39) |
V262E |
probably damaging |
Het |
| Cgnl1 |
C |
T |
9: 71,632,803 (GRCm39) |
G183R |
probably benign |
Het |
| Chd8 |
A |
G |
14: 52,441,341 (GRCm39) |
I2257T |
possibly damaging |
Het |
| Chrna7 |
A |
G |
7: 62,754,809 (GRCm39) |
I266T |
probably damaging |
Het |
| Cyp3a25 |
A |
T |
5: 145,923,685 (GRCm39) |
Y319* |
probably null |
Het |
| Dcdc2a |
A |
T |
13: 25,286,340 (GRCm39) |
I125F |
probably benign |
Het |
| Dcdc2c |
A |
T |
12: 28,585,553 (GRCm39) |
I80N |
|
Het |
| Dmtn |
T |
C |
14: 70,852,732 (GRCm39) |
|
probably null |
Het |
| Dock2 |
T |
C |
11: 34,218,054 (GRCm39) |
N1172S |
probably benign |
Het |
| Dock9 |
A |
G |
14: 121,818,791 (GRCm39) |
S1564P |
probably damaging |
Het |
| Ecel1 |
T |
C |
1: 87,080,853 (GRCm39) |
I350V |
possibly damaging |
Het |
| Eif4enif1 |
C |
T |
11: 3,170,384 (GRCm39) |
L146F |
probably damaging |
Het |
| Ergic1 |
T |
G |
17: 26,843,585 (GRCm39) |
D59E |
probably benign |
Het |
| F2rl2 |
A |
T |
13: 95,838,050 (GRCm39) |
D365V |
possibly damaging |
Het |
| Fbxl16 |
C |
T |
17: 26,036,813 (GRCm39) |
Q265* |
probably null |
Het |
| Fbxw26 |
T |
C |
9: 109,575,135 (GRCm39) |
|
probably benign |
Het |
| Fras1 |
A |
T |
5: 96,929,545 (GRCm39) |
Y3983F |
probably benign |
Het |
| G6pd2 |
T |
A |
5: 61,966,460 (GRCm39) |
D78E |
probably benign |
Het |
| Gas2l2 |
A |
C |
11: 83,314,170 (GRCm39) |
S381A |
possibly damaging |
Het |
| Gm57858 |
A |
G |
3: 36,073,092 (GRCm39) |
S397P |
possibly damaging |
Het |
| Grk2 |
G |
A |
19: 4,338,511 (GRCm39) |
R474C |
probably damaging |
Het |
| Gxylt2 |
T |
A |
6: 100,710,174 (GRCm39) |
V105E |
probably benign |
Het |
| Hexd |
T |
C |
11: 121,107,813 (GRCm39) |
V181A |
probably damaging |
Het |
| Ift70a2 |
T |
C |
2: 75,807,691 (GRCm39) |
T274A |
probably benign |
Het |
| Ik |
T |
A |
18: 36,877,840 (GRCm39) |
D5E |
probably benign |
Het |
| Ilkap |
A |
G |
1: 91,303,973 (GRCm39) |
C163R |
|
Het |
| Itpr3 |
C |
T |
17: 27,334,927 (GRCm39) |
T2147I |
probably damaging |
Het |
| Kif1a |
A |
T |
1: 92,950,173 (GRCm39) |
V1418E |
probably benign |
Het |
| Kif26b |
T |
C |
1: 178,743,815 (GRCm39) |
C1304R |
probably benign |
Het |
| Lmna |
CAGCACGGTGCGTGAGC |
CAGC |
3: 88,389,857 (GRCm39) |
|
probably null |
Het |
| Lvrn |
A |
T |
18: 47,033,609 (GRCm39) |
D940V |
probably damaging |
Het |
| Mill1 |
G |
A |
7: 17,997,027 (GRCm39) |
R206H |
probably benign |
Het |
| Mrgpra1 |
A |
T |
7: 46,985,268 (GRCm39) |
L137Q |
probably damaging |
Het |
| Npc2 |
C |
A |
12: 84,807,638 (GRCm39) |
L73F |
probably benign |
Het |
| Or11g26 |
A |
G |
14: 50,752,669 (GRCm39) |
T3A |
probably benign |
Het |
| Or52i2 |
A |
T |
7: 102,320,011 (GRCm39) |
I295F |
possibly damaging |
Het |
| Or5al1 |
T |
C |
2: 85,990,681 (GRCm39) |
E11G |
probably benign |
Het |
| Or5b97 |
A |
T |
19: 12,879,021 (GRCm39) |
V41E |
probably damaging |
Het |
| Or5j3 |
T |
C |
2: 86,128,718 (GRCm39) |
I186T |
probably benign |
Het |
| Pax7 |
G |
A |
4: 139,556,819 (GRCm39) |
T147M |
probably benign |
Het |
| Pdik1l |
A |
T |
4: 134,006,711 (GRCm39) |
S143T |
unknown |
Het |
| Prkg1 |
T |
G |
19: 30,764,371 (GRCm39) |
T255P |
possibly damaging |
Het |
| Prmt2 |
A |
T |
10: 76,061,213 (GRCm39) |
I91N |
probably damaging |
Het |
| Ptprm |
A |
G |
17: 67,116,484 (GRCm39) |
Y932H |
probably damaging |
Het |
| Ptprz1 |
A |
T |
6: 22,959,694 (GRCm39) |
I64F |
probably damaging |
Het |
| Qrich2 |
T |
C |
11: 116,337,946 (GRCm39) |
K154R |
probably damaging |
Het |
| Rab8b |
T |
C |
9: 66,826,824 (GRCm39) |
D31G |
probably benign |
Het |
| Radil |
A |
G |
5: 142,473,378 (GRCm39) |
S768P |
probably damaging |
Het |
| Rbm5 |
A |
T |
9: 107,622,152 (GRCm39) |
D607E |
probably benign |
Het |
| Reep6 |
T |
A |
10: 80,169,393 (GRCm39) |
V131E |
probably damaging |
Het |
| Rrbp1 |
T |
A |
2: 143,832,099 (GRCm39) |
I23F |
probably damaging |
Het |
| Rubcn |
A |
T |
16: 32,663,481 (GRCm39) |
V385D |
probably benign |
Het |
| Sall2 |
C |
T |
14: 52,552,124 (GRCm39) |
G357D |
possibly damaging |
Het |
| Slc12a6 |
T |
A |
2: 112,174,881 (GRCm39) |
L547H |
probably damaging |
Het |
| Slc16a6 |
T |
C |
11: 109,354,322 (GRCm39) |
T100A |
probably benign |
Het |
| Sptbn2 |
T |
C |
19: 4,800,535 (GRCm39) |
L2250P |
probably damaging |
Het |
| Stab1 |
C |
T |
14: 30,876,901 (GRCm39) |
A808T |
probably benign |
Het |
| Stag1 |
A |
G |
9: 100,810,151 (GRCm39) |
T785A |
probably benign |
Het |
| Stambpl1 |
T |
G |
19: 34,211,535 (GRCm39) |
S199A |
probably benign |
Het |
| Styxl2 |
A |
T |
1: 165,928,654 (GRCm39) |
S319R |
probably damaging |
Het |
| Supt20 |
C |
T |
3: 54,623,015 (GRCm39) |
S496L |
probably benign |
Het |
| Tanc1 |
T |
C |
2: 59,626,196 (GRCm39) |
F518L |
probably damaging |
Het |
| Tdpoz3 |
T |
A |
3: 93,734,156 (GRCm39) |
V277D |
probably benign |
Het |
| Unc45a |
A |
C |
7: 79,975,403 (GRCm39) |
Y934D |
probably damaging |
Het |
| Vmn1r192 |
G |
A |
13: 22,372,119 (GRCm39) |
P34S |
probably benign |
Het |
| Wipf3 |
T |
C |
6: 54,466,004 (GRCm39) |
S421P |
possibly damaging |
Het |
| Zfp296 |
A |
G |
7: 19,314,227 (GRCm39) |
K361E |
possibly damaging |
Het |
| Zfp882 |
T |
A |
8: 72,667,915 (GRCm39) |
N247K |
probably benign |
Het |
| Zfpm2 |
A |
G |
15: 40,965,710 (GRCm39) |
T732A |
possibly damaging |
Het |
|
| Other mutations in Osbpl1a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00585:Osbpl1a
|
APN |
18 |
12,890,683 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
IGL01062:Osbpl1a
|
APN |
18 |
13,038,132 (GRCm39) |
missense |
probably benign |
|
|
IGL01450:Osbpl1a
|
APN |
18 |
13,004,152 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
IGL01531:Osbpl1a
|
APN |
18 |
13,066,638 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01548:Osbpl1a
|
APN |
18 |
12,896,632 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01606:Osbpl1a
|
APN |
18 |
12,889,271 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
IGL01672:Osbpl1a
|
APN |
18 |
12,899,881 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02372:Osbpl1a
|
APN |
18 |
12,974,370 (GRCm39) |
nonsense |
probably null |
|
|
IGL02451:Osbpl1a
|
APN |
18 |
13,047,550 (GRCm39) |
splice site |
probably benign |
|
|
IGL02490:Osbpl1a
|
APN |
18 |
13,015,341 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02884:Osbpl1a
|
APN |
18 |
12,952,635 (GRCm39) |
nonsense |
probably null |
|
|
R0084:Osbpl1a
|
UTSW |
18 |
12,890,669 (GRCm39) |
missense |
probably benign |
0.07 |
|
R0266:Osbpl1a
|
UTSW |
18 |
13,004,220 (GRCm39) |
splice site |
probably null |
|
|
R0565:Osbpl1a
|
UTSW |
18 |
12,892,501 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0605:Osbpl1a
|
UTSW |
18 |
13,015,336 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0899:Osbpl1a
|
UTSW |
18 |
12,890,747 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R1330:Osbpl1a
|
UTSW |
18 |
13,015,251 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1464:Osbpl1a
|
UTSW |
18 |
13,047,615 (GRCm39) |
missense |
probably benign |
|
|
R1464:Osbpl1a
|
UTSW |
18 |
13,047,615 (GRCm39) |
missense |
probably benign |
|
|
R1475:Osbpl1a
|
UTSW |
18 |
12,890,737 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1495:Osbpl1a
|
UTSW |
18 |
12,891,896 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1734:Osbpl1a
|
UTSW |
18 |
12,921,373 (GRCm39) |
splice site |
probably null |
|
|
R1930:Osbpl1a
|
UTSW |
18 |
13,038,251 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1931:Osbpl1a
|
UTSW |
18 |
13,038,251 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2109:Osbpl1a
|
UTSW |
18 |
12,892,457 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2144:Osbpl1a
|
UTSW |
18 |
13,004,230 (GRCm39) |
missense |
probably benign |
0.06 |
|
R2504:Osbpl1a
|
UTSW |
18 |
13,038,088 (GRCm39) |
missense |
probably benign |
0.30 |
|
R2762:Osbpl1a
|
UTSW |
18 |
12,899,956 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R2907:Osbpl1a
|
UTSW |
18 |
13,004,129 (GRCm39) |
unclassified |
probably benign |
|
|
R4306:Osbpl1a
|
UTSW |
18 |
12,952,652 (GRCm39) |
missense |
probably benign |
|
|
R4835:Osbpl1a
|
UTSW |
18 |
12,901,593 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5097:Osbpl1a
|
UTSW |
18 |
12,896,594 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5173:Osbpl1a
|
UTSW |
18 |
12,895,697 (GRCm39) |
missense |
probably benign |
0.12 |
|
R5224:Osbpl1a
|
UTSW |
18 |
13,066,753 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5245:Osbpl1a
|
UTSW |
18 |
12,891,910 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5579:Osbpl1a
|
UTSW |
18 |
13,025,319 (GRCm39) |
missense |
probably benign |
0.22 |
|
R5579:Osbpl1a
|
UTSW |
18 |
12,974,249 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5833:Osbpl1a
|
UTSW |
18 |
12,921,419 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5986:Osbpl1a
|
UTSW |
18 |
13,038,138 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6267:Osbpl1a
|
UTSW |
18 |
12,952,560 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6296:Osbpl1a
|
UTSW |
18 |
12,952,560 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6477:Osbpl1a
|
UTSW |
18 |
12,889,318 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6997:Osbpl1a
|
UTSW |
18 |
12,889,281 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7105:Osbpl1a
|
UTSW |
18 |
12,900,020 (GRCm39) |
missense |
probably benign |
0.17 |
|
R7107:Osbpl1a
|
UTSW |
18 |
12,974,310 (GRCm39) |
nonsense |
probably null |
|
|
R7154:Osbpl1a
|
UTSW |
18 |
12,901,649 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7459:Osbpl1a
|
UTSW |
18 |
13,066,642 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7757:Osbpl1a
|
UTSW |
18 |
13,066,657 (GRCm39) |
missense |
probably benign |
0.44 |
|
R7797:Osbpl1a
|
UTSW |
18 |
13,015,321 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8029:Osbpl1a
|
UTSW |
18 |
13,047,578 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8084:Osbpl1a
|
UTSW |
18 |
13,038,099 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8506:Osbpl1a
|
UTSW |
18 |
12,901,643 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8947:Osbpl1a
|
UTSW |
18 |
12,899,858 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9069:Osbpl1a
|
UTSW |
18 |
13,002,074 (GRCm39) |
intron |
probably benign |
|
|
R9085:Osbpl1a
|
UTSW |
18 |
13,062,093 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9288:Osbpl1a
|
UTSW |
18 |
12,904,402 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9443:Osbpl1a
|
UTSW |
18 |
13,031,244 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9517:Osbpl1a
|
UTSW |
18 |
13,042,965 (GRCm39) |
missense |
probably benign |
|
|
R9600:Osbpl1a
|
UTSW |
18 |
13,015,277 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9658:Osbpl1a
|
UTSW |
18 |
12,889,269 (GRCm39) |
missense |
probably benign |
0.05 |
|
X0027:Osbpl1a
|
UTSW |
18 |
12,892,560 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
Z1177:Osbpl1a
|
UTSW |
18 |
13,039,980 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACACTTCCTGAAAGCCTGG -3'
(R):5'- ACATTCATCATGAGCCCGCTC -3'
Sequencing Primer
(F):5'- TAGCTCTGCCTCTGAACATACAGG -3'
(R):5'- TCTGCCACAGGTTCCGAGTC -3'
|
| Posted On |
2022-11-14 |
Incidental Mutation