Mutagenetix > Incidental Mutation

Incidental Mutation 'R1897:Cep250'

212028

Institutional Source

Beutler Lab

Gene Symbol

Cep250

Ensembl Gene

ENSMUSG00000038241

Gene Name

centrosomal protein 250

Synonyms

B230210E21Rik, Cep2, Inmp

MMRRC Submission

039917-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R1897 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

155798378-155840820 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 155818015 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Glutamic Acid to Glycine at position 789 (E789G)

Ref Sequence

ENSEMBL: ENSMUSP00000105248 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000039994] [ENSMUST00000094421] [ENSMUST00000109619] [ENSMUST00000124812] [ENSMUST00000151569]

AlphaFold

Q60952

Predicted Effect

probably damaging
Transcript: ENSMUST00000039994
AA Change: E788G

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000038255
Gene: ENSMUSG00000038241
AA Change: E788G

Domain	Start	End	E-Value	Type
Pfam:Rootletin	38	215	4.2e-56	PFAM
low complexity region	228	241	N/A	INTRINSIC
coiled coil region	248	327	N/A	INTRINSIC
internal_repeat_1	444	460	1.47e-18	PROSPERO
internal_repeat_1	465	481	1.47e-18	PROSPERO
low complexity region	495	506	N/A	INTRINSIC
low complexity region	557	580	N/A	INTRINSIC
low complexity region	583	595	N/A	INTRINSIC
low complexity region	635	650	N/A	INTRINSIC
low complexity region	669	677	N/A	INTRINSIC
low complexity region	688	703	N/A	INTRINSIC
low complexity region	708	719	N/A	INTRINSIC
low complexity region	896	914	N/A	INTRINSIC
low complexity region	990	1007	N/A	INTRINSIC
low complexity region	1043	1053	N/A	INTRINSIC
low complexity region	1138	1143	N/A	INTRINSIC
low complexity region	1182	1195	N/A	INTRINSIC
coiled coil region	1257	1687	N/A	INTRINSIC
low complexity region	1872	1895	N/A	INTRINSIC
low complexity region	1919	1933	N/A	INTRINSIC
low complexity region	1941	1960	N/A	INTRINSIC
internal_repeat_2	2002	2052	3.9e-6	PROSPERO
coiled coil region	2068	2169	N/A	INTRINSIC
coiled coil region	2196	2217	N/A	INTRINSIC
coiled coil region	2251	2310	N/A	INTRINSIC
low complexity region	2325	2338	N/A	INTRINSIC
coiled coil region	2340	2366	N/A	INTRINSIC
low complexity region	2379	2388	N/A	INTRINSIC

Predicted Effect

probably damaging
Transcript: ENSMUST00000094421
AA Change: E768G

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000091988
Gene: ENSMUSG00000038241
AA Change: E768G

Domain	Start	End	E-Value	Type
Pfam:Rootletin	38	215	5.4e-56	PFAM
low complexity region	228	241	N/A	INTRINSIC
coiled coil region	248	357	N/A	INTRINSIC
coiled coil region	400	1165	N/A	INTRINSIC
coiled coil region	1237	1667	N/A	INTRINSIC
low complexity region	1852	1875	N/A	INTRINSIC
low complexity region	1899	1913	N/A	INTRINSIC
low complexity region	1921	1940	N/A	INTRINSIC
internal_repeat_1	1982	2032	3.35e-6	PROSPERO
coiled coil region	2048	2149	N/A	INTRINSIC
coiled coil region	2176	2197	N/A	INTRINSIC
coiled coil region	2231	2290	N/A	INTRINSIC
low complexity region	2305	2318	N/A	INTRINSIC
coiled coil region	2320	2346	N/A	INTRINSIC
low complexity region	2359	2368	N/A	INTRINSIC

Predicted Effect

probably damaging
Transcript: ENSMUST00000109619
AA Change: E789G

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000105248
Gene: ENSMUSG00000038241
AA Change: E789G

Domain	Start	End	E-Value	Type
Pfam:Rootletin	38	214	4.1e-60	PFAM
low complexity region	215	225	N/A	INTRINSIC
low complexity region	228	241	N/A	INTRINSIC
coiled coil region	248	357	N/A	INTRINSIC
internal_repeat_1	445	461	1.51e-18	PROSPERO
internal_repeat_1	466	482	1.51e-18	PROSPERO
low complexity region	496	507	N/A	INTRINSIC
low complexity region	558	581	N/A	INTRINSIC
low complexity region	584	596	N/A	INTRINSIC
low complexity region	636	651	N/A	INTRINSIC
low complexity region	670	678	N/A	INTRINSIC
low complexity region	689	704	N/A	INTRINSIC
low complexity region	709	720	N/A	INTRINSIC
low complexity region	897	915	N/A	INTRINSIC
low complexity region	991	1008	N/A	INTRINSIC
low complexity region	1044	1054	N/A	INTRINSIC
low complexity region	1139	1144	N/A	INTRINSIC
low complexity region	1183	1196	N/A	INTRINSIC
coiled coil region	1258	1688	N/A	INTRINSIC
low complexity region	1873	1896	N/A	INTRINSIC
low complexity region	1920	1934	N/A	INTRINSIC
low complexity region	1942	1961	N/A	INTRINSIC
internal_repeat_2	2003	2053	3.95e-6	PROSPERO
coiled coil region	2069	2170	N/A	INTRINSIC
coiled coil region	2197	2218	N/A	INTRINSIC
coiled coil region	2252	2311	N/A	INTRINSIC
low complexity region	2326	2339	N/A	INTRINSIC
coiled coil region	2341	2367	N/A	INTRINSIC
low complexity region	2380	2389	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000124812

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000148191

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000149905

Predicted Effect

probably benign
Transcript: ENSMUST00000151569

SMART Domains

Protein: ENSMUSP00000114426
Gene: ENSMUSG00000038241

Domain	Start	End	E-Value	Type
Pfam:Rootletin	38	215	1.3e-56	PFAM
low complexity region	228	241	N/A	INTRINSIC
coiled coil region	248	327	N/A	INTRINSIC
internal_repeat_1	444	460	1.16e-14	PROSPERO
internal_repeat_1	465	481	1.16e-14	PROSPERO
low complexity region	495	506	N/A	INTRINSIC
low complexity region	557	580	N/A	INTRINSIC
low complexity region	583	595	N/A	INTRINSIC
low complexity region	635	650	N/A	INTRINSIC
low complexity region	669	677	N/A	INTRINSIC
low complexity region	688	703	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000155160

Meta Mutation Damage Score

0.1089

Coding Region Coverage

1x: 97.4%
3x: 96.8%
10x: 95.3%
20x: 92.8%

Validation Efficiency

99% (72/73)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a core centrosomal protein required for centriole-centriole cohesion during interphase of the cell cycle. The encoded protein dissociates from the centrosomes when parental centrioles separate at the beginning of mitosis. The protein associates with and is phosphorylated by NIMA-related kinase 2, which is also associated with the centrosome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]

Allele List at MGI

Other mutations in this stock

Total: 70 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Acbd6	A	G	1: 155,434,564 (GRCm39)	S61G	probably damaging	Het
Acot12	A	G	13: 91,932,516 (GRCm39)	N504S	probably benign	Het
Adcy3	C	T	12: 4,223,450 (GRCm39)		probably benign	Het
Adcyap1r1	A	T	6: 55,456,179 (GRCm39)	H168L	probably damaging	Het
Adgrd1	A	G	5: 129,206,065 (GRCm39)	E213G	probably benign	Het
Aldh1l2	G	T	10: 83,338,389 (GRCm39)	T510K	probably damaging	Het
Apol7e	A	T	15: 77,602,094 (GRCm39)	M231L	probably benign	Het
Asb1	C	A	1: 91,474,647 (GRCm39)		probably null	Het
Atf7ip2	C	T	16: 10,028,948 (GRCm39)	P160L	probably damaging	Het
Atp8a1	A	G	5: 67,895,772 (GRCm39)	L554P	probably damaging	Het
Ccdc18	A	T	5: 108,343,908 (GRCm39)	M884L	probably benign	Het
Ccdc93	A	G	1: 121,418,941 (GRCm39)	I499V	probably benign	Het
Ccl20	A	G	1: 83,095,616 (GRCm39)	D60G	probably damaging	Het
Cdhr3	T	C	12: 33,095,192 (GRCm39)	T626A	possibly damaging	Het
Cmpk2	T	C	12: 26,524,046 (GRCm39)	L281P	probably damaging	Het
Col6a6	A	T	9: 105,662,943 (GRCm39)	M198K	possibly damaging	Het
Crocc	G	A	4: 140,746,047 (GRCm39)	R1691C	probably damaging	Het
Csf1	C	T	3: 107,655,595 (GRCm39)	V90M	probably damaging	Het
Cul2	T	G	18: 3,414,164 (GRCm39)	M86R	probably benign	Het
Dbndd2	T	C	2: 164,330,584 (GRCm39)	F79S	probably damaging	Het
Dkk1	G	T	19: 30,526,678 (GRCm39)	N34K	possibly damaging	Het
Dnah6	T	A	6: 73,158,745 (GRCm39)	L619F	probably benign	Het
Eif2b5	T	C	16: 20,325,787 (GRCm39)	V588A	probably damaging	Het
Elf3	A	T	1: 135,184,875 (GRCm39)	Y104N	probably damaging	Het
Fahd2a	T	C	2: 127,278,530 (GRCm39)	D272G	probably damaging	Het
Fbxw15	A	T	9: 109,387,271 (GRCm39)	C188*	probably null	Het
Fbxw8	T	C	5: 118,266,941 (GRCm39)	Y174C	probably benign	Het
Gnl1	C	A	17: 36,299,584 (GRCm39)	P585Q	possibly damaging	Het
Greb1l	T	C	18: 10,498,992 (GRCm39)	S292P	probably benign	Het
Gsk3b	G	A	16: 38,037,446 (GRCm39)		probably null	Het
Hcls1	C	T	16: 36,783,005 (GRCm39)	P452L	probably damaging	Het
Hdlbp	A	T	1: 93,350,007 (GRCm39)		probably benign	Het
Hecw1	A	G	13: 14,552,525 (GRCm39)	S25P	probably damaging	Het
Hells	T	C	19: 38,928,928 (GRCm39)	V100A	probably benign	Het
Isl1	C	T	13: 116,439,866 (GRCm39)	E161K	probably benign	Het
Klra9	G	T	6: 130,162,555 (GRCm39)	N160K	possibly damaging	Het
Lama4	T	C	10: 38,936,182 (GRCm39)	V619A	probably damaging	Het
Mpc1	G	A	17: 8,515,710 (GRCm39)	R134Q	possibly damaging	Het
Myo5c	A	T	9: 75,199,523 (GRCm39)	N1377I	probably benign	Het
Myrf	T	C	19: 10,195,596 (GRCm39)	I607V	probably benign	Het
Or2g1	T	G	17: 38,107,075 (GRCm39)	S247A	probably benign	Het
Or8g53	A	T	9: 39,683,361 (GRCm39)	I245K	probably damaging	Het
Pik3c2b	A	G	1: 132,994,654 (GRCm39)	D206G	possibly damaging	Het
Pipox	A	G	11: 77,773,568 (GRCm39)	Y228H	probably damaging	Het
Pitrm1	T	A	13: 6,610,131 (GRCm39)	V401D	possibly damaging	Het
Plod1	C	T	4: 148,010,657 (GRCm39)	E265K	probably damaging	Het
Ptpn21	A	T	12: 98,646,664 (GRCm39)		probably null	Het
Qars1	C	T	9: 108,391,282 (GRCm39)	Q7*	probably null	Het
Rpap2	T	A	5: 107,780,961 (GRCm39)	V479E	possibly damaging	Het
Rsf1	G	A	7: 97,229,117 (GRCm39)		probably benign	Het
Rusc2	A	G	4: 43,421,749 (GRCm39)	Y723C	probably damaging	Het
Ryr2	A	T	13: 11,765,818 (GRCm39)	M1306K	probably benign	Het
Sesn3	A	C	9: 14,219,941 (GRCm39)	Y110S	probably damaging	Het
Sgce	C	T	6: 4,691,511 (GRCm39)	V319I	probably benign	Het
Slc15a5	G	T	6: 138,056,762 (GRCm39)	F51L	possibly damaging	Het
Slit2	T	A	5: 48,395,765 (GRCm39)	C723S	probably damaging	Het
Sncaip	A	G	18: 53,027,862 (GRCm39)		probably null	Het
Snx2	T	A	18: 53,330,950 (GRCm39)	D138E	probably damaging	Het
Spef2	A	T	15: 9,729,740 (GRCm39)	L126*	probably null	Het
Stam	T	C	2: 14,133,837 (GRCm39)	S195P	probably damaging	Het
Strn	T	C	17: 78,990,271 (GRCm39)	I82V	probably benign	Het
Synj2	T	A	17: 6,072,412 (GRCm39)	C202*	probably null	Het
Tecpr2	A	G	12: 110,899,681 (GRCm39)	D683G	probably benign	Het
Tfec	A	G	6: 16,835,307 (GRCm39)	V157A	probably damaging	Het
Tff1	T	G	17: 31,383,912 (GRCm39)	Q28P	probably benign	Het
Vmn2r86	A	G	10: 130,288,314 (GRCm39)	Y396H	probably damaging	Het
Vmn2r87	A	T	10: 130,307,829 (GRCm39)	M803K	probably damaging	Het
Vmn2r90	A	G	17: 17,953,566 (GRCm39)	K577E	probably damaging	Het
Vrk1	T	C	12: 106,002,799 (GRCm39)		probably benign	Het
Wdr20	A	G	12: 110,760,157 (GRCm39)	T348A	probably benign	Het

Other mutations in Cep250

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00484:Cep250	APN	2	155,833,249 (GRCm39)	missense	probably benign	0.00
IGL01077:Cep250	APN	2	155,804,054 (GRCm39)	missense	probably damaging	1.00
IGL01084:Cep250	APN	2	155,840,313 (GRCm39)	missense	probably benign	0.00
IGL01400:Cep250	APN	2	155,840,211 (GRCm39)	missense	possibly damaging	0.78
IGL01570:Cep250	APN	2	155,809,583 (GRCm39)	splice site	probably benign
IGL01583:Cep250	APN	2	155,818,069 (GRCm39)	missense	probably damaging	0.99
IGL01590:Cep250	APN	2	155,834,237 (GRCm39)	missense	possibly damaging	0.80
IGL01647:Cep250	APN	2	155,825,296 (GRCm39)	missense	probably benign	0.02
IGL01959:Cep250	APN	2	155,825,279 (GRCm39)	missense	possibly damaging	0.63
IGL02066:Cep250	APN	2	155,818,441 (GRCm39)	missense	probably damaging	1.00
IGL02219:Cep250	APN	2	155,833,514 (GRCm39)	missense	probably benign	0.26
IGL02322:Cep250	APN	2	155,832,248 (GRCm39)	missense	probably damaging	1.00
IGL02728:Cep250	APN	2	155,825,198 (GRCm39)	unclassified	probably benign
IGL02955:Cep250	APN	2	155,817,676 (GRCm39)	missense	probably benign	0.01
IGL03369:Cep250	APN	2	155,832,191 (GRCm39)	missense	probably benign	0.00
R0366:Cep250	UTSW	2	155,830,321 (GRCm39)	missense	probably benign	0.00
R0403:Cep250	UTSW	2	155,834,269 (GRCm39)	missense	probably damaging	0.99
R0441:Cep250	UTSW	2	155,813,924 (GRCm39)	missense	possibly damaging	0.82
R0482:Cep250	UTSW	2	155,806,894 (GRCm39)	splice site	probably benign
R0507:Cep250	UTSW	2	155,834,452 (GRCm39)	missense	possibly damaging	0.60
R0614:Cep250	UTSW	2	155,812,017 (GRCm39)	nonsense	probably null
R0855:Cep250	UTSW	2	155,806,031 (GRCm39)	missense	probably damaging	1.00
R0973:Cep250	UTSW	2	155,806,209 (GRCm39)	splice site	probably benign
R1137:Cep250	UTSW	2	155,832,760 (GRCm39)	missense	probably benign	0.05
R1270:Cep250	UTSW	2	155,832,601 (GRCm39)	missense	probably benign	0.01
R1313:Cep250	UTSW	2	155,813,999 (GRCm39)	missense	probably damaging	0.98
R1313:Cep250	UTSW	2	155,813,999 (GRCm39)	missense	probably damaging	0.98
R1470:Cep250	UTSW	2	155,832,995 (GRCm39)	missense	probably damaging	0.99
R1470:Cep250	UTSW	2	155,832,995 (GRCm39)	missense	probably damaging	0.99
R1703:Cep250	UTSW	2	155,807,466 (GRCm39)	missense	probably benign	0.23
R1705:Cep250	UTSW	2	155,805,706 (GRCm39)	missense	probably damaging	1.00
R1740:Cep250	UTSW	2	155,815,276 (GRCm39)	missense	probably damaging	0.99
R1796:Cep250	UTSW	2	155,834,107 (GRCm39)	missense	possibly damaging	0.88
R1900:Cep250	UTSW	2	155,827,294 (GRCm39)	critical splice donor site	probably null
R1958:Cep250	UTSW	2	155,818,301 (GRCm39)	splice site	probably null
R1974:Cep250	UTSW	2	155,831,424 (GRCm39)	missense	probably damaging	0.96
R2015:Cep250	UTSW	2	155,823,373 (GRCm39)	missense	probably damaging	0.96
R2033:Cep250	UTSW	2	155,812,812 (GRCm39)	missense	probably damaging	0.99
R2224:Cep250	UTSW	2	155,833,737 (GRCm39)	missense	possibly damaging	0.94
R2266:Cep250	UTSW	2	155,818,090 (GRCm39)	missense	probably benign	0.13
R2278:Cep250	UTSW	2	155,834,552 (GRCm39)	missense	probably damaging	1.00
R2332:Cep250	UTSW	2	155,832,527 (GRCm39)	missense	probably damaging	1.00
R2364:Cep250	UTSW	2	155,834,552 (GRCm39)	missense	probably damaging	1.00
R2366:Cep250	UTSW	2	155,834,552 (GRCm39)	missense	probably damaging	1.00
R2367:Cep250	UTSW	2	155,834,552 (GRCm39)	missense	probably damaging	1.00
R2385:Cep250	UTSW	2	155,816,261 (GRCm39)	missense	probably damaging	1.00
R2830:Cep250	UTSW	2	155,825,236 (GRCm39)	missense	probably benign	0.00
R2895:Cep250	UTSW	2	155,834,042 (GRCm39)	missense	probably benign	0.00
R2965:Cep250	UTSW	2	155,836,798 (GRCm39)	missense	probably benign	0.44
R2966:Cep250	UTSW	2	155,836,798 (GRCm39)	missense	probably benign	0.44
R3016:Cep250	UTSW	2	155,833,208 (GRCm39)	missense	probably damaging	1.00
R3052:Cep250	UTSW	2	155,832,968 (GRCm39)	missense	probably damaging	0.99
R3424:Cep250	UTSW	2	155,823,381 (GRCm39)	missense	probably benign	0.02
R3930:Cep250	UTSW	2	155,834,552 (GRCm39)	missense	probably damaging	1.00
R4085:Cep250	UTSW	2	155,834,552 (GRCm39)	missense	probably damaging	1.00
R4087:Cep250	UTSW	2	155,834,552 (GRCm39)	missense	probably damaging	1.00
R4088:Cep250	UTSW	2	155,834,552 (GRCm39)	missense	probably damaging	1.00
R4090:Cep250	UTSW	2	155,834,552 (GRCm39)	missense	probably damaging	1.00
R4110:Cep250	UTSW	2	155,834,552 (GRCm39)	missense	probably damaging	1.00
R4355:Cep250	UTSW	2	155,833,445 (GRCm39)	missense	probably damaging	1.00
R4601:Cep250	UTSW	2	155,803,973 (GRCm39)	missense	probably benign	0.10
R4721:Cep250	UTSW	2	155,812,119 (GRCm39)	missense	probably damaging	1.00
R4995:Cep250	UTSW	2	155,830,236 (GRCm39)	missense	probably damaging	1.00
R5053:Cep250	UTSW	2	155,804,848 (GRCm39)	missense	possibly damaging	0.77
R5090:Cep250	UTSW	2	155,818,324 (GRCm39)	missense	probably damaging	1.00
R5744:Cep250	UTSW	2	155,823,394 (GRCm39)	missense	possibly damaging	0.60
R5775:Cep250	UTSW	2	155,811,294 (GRCm39)	missense	possibly damaging	0.92
R5986:Cep250	UTSW	2	155,821,197 (GRCm39)	missense	probably damaging	1.00
R6112:Cep250	UTSW	2	155,836,503 (GRCm39)	missense	possibly damaging	0.95
R6152:Cep250	UTSW	2	155,823,358 (GRCm39)	missense	possibly damaging	0.94
R6823:Cep250	UTSW	2	155,823,379 (GRCm39)	missense	probably benign	0.02
R6859:Cep250	UTSW	2	155,834,446 (GRCm39)	missense	probably benign	0.24
R6900:Cep250	UTSW	2	155,838,190 (GRCm39)	critical splice acceptor site	probably null
R7107:Cep250	UTSW	2	155,837,314 (GRCm39)	missense	probably benign	0.00
R7131:Cep250	UTSW	2	155,806,997 (GRCm39)	missense	probably damaging	1.00
R7178:Cep250	UTSW	2	155,815,375 (GRCm39)	nonsense	probably null
R7241:Cep250	UTSW	2	155,833,472 (GRCm39)	missense	probably benign	0.20
R7264:Cep250	UTSW	2	155,821,071 (GRCm39)	missense	probably damaging	0.99
R7290:Cep250	UTSW	2	155,834,682 (GRCm39)	missense	probably benign	0.03
R7367:Cep250	UTSW	2	155,811,227 (GRCm39)	missense	probably benign	0.00
R7397:Cep250	UTSW	2	155,823,331 (GRCm39)	missense	probably damaging	0.99
R7768:Cep250	UTSW	2	155,827,929 (GRCm39)	missense
R7823:Cep250	UTSW	2	155,807,336 (GRCm39)	missense	possibly damaging	0.89
R8152:Cep250	UTSW	2	155,811,227 (GRCm39)	missense	probably benign	0.00
R8331:Cep250	UTSW	2	155,832,173 (GRCm39)	missense	probably damaging	1.00
R8559:Cep250	UTSW	2	155,834,656 (GRCm39)	missense	probably damaging	0.99
R8972:Cep250	UTSW	2	155,812,042 (GRCm39)	missense	unknown
R8973:Cep250	UTSW	2	155,812,042 (GRCm39)	missense	unknown
R8974:Cep250	UTSW	2	155,812,042 (GRCm39)	missense	unknown
R8975:Cep250	UTSW	2	155,812,042 (GRCm39)	missense	unknown
R8976:Cep250	UTSW	2	155,812,042 (GRCm39)	missense	unknown
R9072:Cep250	UTSW	2	155,834,035 (GRCm39)	missense	probably benign	0.01
R9123:Cep250	UTSW	2	155,812,042 (GRCm39)	missense	unknown
R9127:Cep250	UTSW	2	155,812,042 (GRCm39)	missense	unknown
R9128:Cep250	UTSW	2	155,812,042 (GRCm39)	missense	unknown
R9167:Cep250	UTSW	2	155,828,920 (GRCm39)	missense
R9189:Cep250	UTSW	2	155,818,350 (GRCm39)	missense	probably benign	0.00
R9198:Cep250	UTSW	2	155,830,354 (GRCm39)	critical splice donor site	probably null
R9227:Cep250	UTSW	2	155,812,042 (GRCm39)	missense	unknown
R9228:Cep250	UTSW	2	155,812,042 (GRCm39)	missense	unknown
R9292:Cep250	UTSW	2	155,832,688 (GRCm39)	missense	probably damaging	0.99
R9516:Cep250	UTSW	2	155,833,459 (GRCm39)	missense	probably benign	0.00
R9723:Cep250	UTSW	2	155,823,337 (GRCm39)	missense	probably benign	0.00
R9760:Cep250	UTSW	2	155,818,473 (GRCm39)	missense	probably benign	0.02
X0061:Cep250	UTSW	2	155,803,905 (GRCm39)	missense	probably benign	0.05
Z1177:Cep250	UTSW	2	155,818,387 (GRCm39)	missense	probably benign	0.03

Predicted Primers

PCR Primer
(F):5'- TAGCCAAGCTAAGCTCCCTGTC -3'
(R):5'- AGCAACTTCCTCTCAGAGCC -3'

Sequencing Primer
(F):5'- CCTCAGTGTATGCATTCTAAAAGAGC -3'
(R):5'- TCTGGCAGAAGAAAGCTCTCACTG -3'

Posted On

2014-06-30