Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL00978:Vmn2r102'

29355

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn2r102

Ensembl Gene

ENSMUSG00000095961

Gene Name

vomeronasal 2, receptor 102

Synonyms

EG224572

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL00978

Quality Score

Status

Chromosome

Chromosomal Location

19660399-19694748 bp(+) (GRCm38)

Type of Mutation

splice site (5 bp from exon)

DNA Base Change (assembly)

G to T at 19678923 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000126559 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000171741]

AlphaFold

L7N279

Predicted Effect

probably null
Transcript: ENSMUST00000171741

SMART Domains

Protein: ENSMUSP00000126559
Gene: ENSMUSG00000095961

Domain	Start	End	E-Value	Type
signal peptide	1	19	N/A	INTRINSIC
Pfam:ANF_receptor	82	448	5.2e-38	PFAM
Pfam:NCD3G	509	562	1.1e-21	PFAM
Pfam:7tm_3	595	830	1.8e-53	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 35 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
0610009L18Rik	T	C	11: 120,350,947		probably benign	Het
Alpk2	A	T	18: 65,291,534		probably benign	Het
Angptl8	T	C	9: 21,837,053		probably benign	Het
AU040320	T	A	4: 126,828,839	D383E	probably benign	Het
Cep97	C	T	16: 55,924,960		probably benign	Het
Clcn4	A	T	7: 7,287,673	L649H	probably damaging	Het
Col5a2	T	C	1: 45,376,739	N1416S	probably benign	Het
Erbb2	C	T	11: 98,435,630	P1027S	probably damaging	Het
Eya1	A	G	1: 14,270,701		probably benign	Het
Gfm2	T	C	13: 97,162,977	I402T	probably benign	Het
Gmeb2	A	T	2: 181,259,043	V187E	probably benign	Het
Hectd1	T	C	12: 51,791,390	H662R	possibly damaging	Het
Ifne	T	C	4: 88,880,031	Q50R	probably benign	Het
Kidins220	A	G	12: 25,057,474	D1642G	probably damaging	Het
Klhl32	T	A	4: 24,682,245	D146V	probably damaging	Het
Krt36	T	C	11: 100,102,948	I355V	probably damaging	Het
Lrrcc1	T	A	3: 14,536,128	S73R	possibly damaging	Het
Ltbp3	A	T	19: 5,754,019	H853L	probably benign	Het
Map3k5	G	A	10: 20,141,567	R1369Q	probably damaging	Het
Mcm8	A	G	2: 132,821,406	N148S	probably benign	Het
Mylk3	A	T	8: 85,355,526	L211*	probably null	Het
Nras	T	C	3: 103,058,916		probably benign	Het
Olfr135	A	T	17: 38,208,982	I246F	probably damaging	Het
Olfr670	A	T	7: 104,960,716	N5K	probably damaging	Het
Os9	A	T	10: 127,120,509	Y66N	probably damaging	Het
Pitpnm1	A	G	19: 4,101,228	D15G	possibly damaging	Het
Reg3a	A	T	6: 78,382,301	R95*	probably null	Het
Rnf17	C	T	14: 56,512,271	P1425S	probably damaging	Het
Smad2	T	C	18: 76,299,775		probably benign	Het
Ttll5	C	T	12: 85,933,482	Q76*	probably null	Het
Uri1	A	T	7: 37,996,731		probably benign	Het
Vmn2r70	T	G	7: 85,563,799	M467L	probably benign	Het
Zfp318	T	A	17: 46,413,726	D2218E	possibly damaging	Het
Zfp692	T	C	11: 58,314,029	I405T	possibly damaging	Het
Zfp692	A	G	11: 58,309,998	H235R	possibly damaging	Het

Other mutations in Vmn2r102

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00944:Vmn2r102	APN	17	19678892	missense	probably damaging	1.00
IGL00974:Vmn2r102	APN	17	19677509	missense	possibly damaging	0.93
IGL01589:Vmn2r102	APN	17	19678804	missense	probably benign
IGL01738:Vmn2r102	APN	17	19677758	missense	probably damaging	1.00
IGL01994:Vmn2r102	APN	17	19660469	missense	probably benign	0.00
IGL02066:Vmn2r102	APN	17	19693929	missense	probably benign	0.01
IGL02525:Vmn2r102	APN	17	19681185	missense	probably benign
IGL02589:Vmn2r102	APN	17	19681218	missense	probably damaging	1.00
IGL02814:Vmn2r102	APN	17	19677908	missense	probably damaging	1.00
IGL03028:Vmn2r102	APN	17	19694066	missense	possibly damaging	0.92
IGL03162:Vmn2r102	APN	17	19694024	missense	probably damaging	1.00
PIT4431001:Vmn2r102	UTSW	17	19676696	missense	possibly damaging	0.68
R0042:Vmn2r102	UTSW	17	19660589	missense	probably damaging	0.98
R0131:Vmn2r102	UTSW	17	19678763	missense	probably benign	0.42
R0131:Vmn2r102	UTSW	17	19678763	missense	probably benign	0.42
R0132:Vmn2r102	UTSW	17	19678763	missense	probably benign	0.42
R0268:Vmn2r102	UTSW	17	19677850	missense	probably benign	0.00
R0441:Vmn2r102	UTSW	17	19694368	missense	probably damaging	1.00
R0583:Vmn2r102	UTSW	17	19676781	missense	probably benign	0.01
R0600:Vmn2r102	UTSW	17	19678015	missense	probably benign	0.00
R0606:Vmn2r102	UTSW	17	19678844	missense	possibly damaging	0.93
R0674:Vmn2r102	UTSW	17	19677867	missense	probably benign	0.00
R0709:Vmn2r102	UTSW	17	19677619	missense	probably benign	0.01
R0879:Vmn2r102	UTSW	17	19694192	missense	probably damaging	1.00
R1349:Vmn2r102	UTSW	17	19660625	splice site	probably benign
R1473:Vmn2r102	UTSW	17	19694581	missense	probably benign	0.00
R1630:Vmn2r102	UTSW	17	19678770	missense	possibly damaging	0.60
R1727:Vmn2r102	UTSW	17	19677508	missense	probably damaging	0.99
R1759:Vmn2r102	UTSW	17	19694493	missense	probably damaging	1.00
R1809:Vmn2r102	UTSW	17	19677619	missense	probably benign	0.01
R2013:Vmn2r102	UTSW	17	19676744	missense	probably benign	0.03
R2086:Vmn2r102	UTSW	17	19676687	missense	probably damaging	1.00
R2241:Vmn2r102	UTSW	17	19676741	missense	probably benign	0.00
R2378:Vmn2r102	UTSW	17	19694668	missense	probably damaging	1.00
R3814:Vmn2r102	UTSW	17	19678831	missense	probably damaging	0.98
R3827:Vmn2r102	UTSW	17	19694525	missense	probably damaging	1.00
R4159:Vmn2r102	UTSW	17	19677826	missense	probably damaging	1.00
R4505:Vmn2r102	UTSW	17	19660583	missense	probably benign	0.00
R4515:Vmn2r102	UTSW	17	19681213	missense	probably damaging	1.00
R4517:Vmn2r102	UTSW	17	19681213	missense	probably damaging	1.00
R4534:Vmn2r102	UTSW	17	19694713	missense	probably benign
R4535:Vmn2r102	UTSW	17	19694713	missense	probably benign
R4662:Vmn2r102	UTSW	17	19681162	missense	probably damaging	1.00
R4708:Vmn2r102	UTSW	17	19694314	missense	probably benign	0.00
R4734:Vmn2r102	UTSW	17	19677533	missense	probably damaging	1.00
R4834:Vmn2r102	UTSW	17	19677941	missense	probably damaging	0.99
R4927:Vmn2r102	UTSW	17	19660399	start codon destroyed	probably benign	0.00
R5077:Vmn2r102	UTSW	17	19677572	missense	probably benign	0.20
R5181:Vmn2r102	UTSW	17	19676741	missense	probably benign	0.00
R5277:Vmn2r102	UTSW	17	19694131	missense	possibly damaging	0.49
R5418:Vmn2r102	UTSW	17	19694153	missense	probably damaging	1.00
R5810:Vmn2r102	UTSW	17	19677542	missense	probably benign	0.20
R5864:Vmn2r102	UTSW	17	19694681	missense	possibly damaging	0.55
R6168:Vmn2r102	UTSW	17	19694140	missense	possibly damaging	0.83
R6266:Vmn2r102	UTSW	17	19678745	missense	probably benign
R6432:Vmn2r102	UTSW	17	19681221	missense	possibly damaging	0.61
R6487:Vmn2r102	UTSW	17	19677907	missense	probably damaging	1.00
R6597:Vmn2r102	UTSW	17	19694188	missense	probably damaging	0.99
R6797:Vmn2r102	UTSW	17	19660432	nonsense	probably null
R7009:Vmn2r102	UTSW	17	19694194	missense	probably damaging	0.99
R7098:Vmn2r102	UTSW	17	19694408	missense	probably damaging	1.00
R7134:Vmn2r102	UTSW	17	19677487	missense	probably benign	0.01
R7463:Vmn2r102	UTSW	17	19676624	missense	probably damaging	1.00
R7511:Vmn2r102	UTSW	17	19681143	missense	probably damaging	1.00
R7512:Vmn2r102	UTSW	17	19694101	missense	probably damaging	1.00
R7556:Vmn2r102	UTSW	17	19677831	missense	probably benign
R8126:Vmn2r102	UTSW	17	19660450	missense	probably benign	0.02
R8385:Vmn2r102	UTSW	17	19693826	missense	possibly damaging	0.89
R8410:Vmn2r102	UTSW	17	19677934	missense	possibly damaging	0.85
R9045:Vmn2r102	UTSW	17	19660579	missense	probably benign	0.00
R9267:Vmn2r102	UTSW	17	19676666	missense	probably damaging	1.00
R9325:Vmn2r102	UTSW	17	19677296	missense	probably damaging	1.00
R9363:Vmn2r102	UTSW	17	19677352	missense	probably benign	0.04
R9524:Vmn2r102	UTSW	17	19677302	missense	possibly damaging	0.74
R9747:Vmn2r102	UTSW	17	19677867	missense	probably benign	0.00
Z1176:Vmn2r102	UTSW	17	19694043	nonsense	probably null

Posted On

2013-04-17