Incidental Mutation 'R4840:Rufy4'
| ID |
371686 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Rufy4
|
| Ensembl Gene |
ENSMUSG00000061815 |
| Gene Name |
RUN and FYVE domain containing 4 |
| Synonyms |
F930048N03Rik |
| MMRRC Submission |
042453-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.202)
|
| Stock # |
R4840 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
74164700-74187382 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to A
at 74168198 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Lysine
at position 82
(T82K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000115873
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000080167]
[ENSMUST00000127134]
[ENSMUST00000169786]
[ENSMUST00000191104]
[ENSMUST00000212888]
|
| AlphaFold |
Q3TYX8 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000080167
|
| SMART Domains |
Protein: ENSMUSP00000079062
Gene: ENSMUSG00000061815
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:RUN
|
2 |
81 |
1.5e-8 |
PFAM |
|
coiled coil region
|
331 |
404 |
N/A |
INTRINSIC |
|
Blast:FYVE
|
415 |
472 |
2e-6 |
BLAST |
|
SCOP:d1vfya_
|
428 |
473 |
4e-7 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000127134
AA Change: T82K
PolyPhen 2
Score 0.817 (Sensitivity: 0.84; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000115873
Gene: ENSMUSG00000061815
AA Change: T82K
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:RUN
|
41 |
165 |
6.2e-10 |
PFAM |
|
coiled coil region
|
415 |
488 |
N/A |
INTRINSIC |
|
Blast:FYVE
|
499 |
556 |
2e-6 |
BLAST |
|
SCOP:d1vfya_
|
512 |
557 |
3e-7 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000169786
|
| SMART Domains |
Protein: ENSMUSP00000127715
Gene: ENSMUSG00000055322
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
33 |
N/A |
INTRINSIC |
|
C1
|
62 |
108 |
1.77e-2 |
SMART |
|
low complexity region
|
154 |
167 |
N/A |
INTRINSIC |
|
SCOP:d1d5ra2
|
176 |
348 |
3e-32 |
SMART |
|
PTEN_C2
|
350 |
477 |
1.12e-51 |
SMART |
|
low complexity region
|
822 |
833 |
N/A |
INTRINSIC |
|
low complexity region
|
905 |
922 |
N/A |
INTRINSIC |
|
low complexity region
|
1227 |
1239 |
N/A |
INTRINSIC |
|
low complexity region
|
1284 |
1300 |
N/A |
INTRINSIC |
|
low complexity region
|
1459 |
1470 |
N/A |
INTRINSIC |
|
low complexity region
|
1518 |
1530 |
N/A |
INTRINSIC |
|
SH2
|
1614 |
1716 |
6.85e-17 |
SMART |
|
PTB
|
1747 |
1888 |
1.69e-29 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000191104
|
| SMART Domains |
Protein: ENSMUSP00000140317
Gene: ENSMUSG00000055322
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
33 |
N/A |
INTRINSIC |
|
C1
|
62 |
108 |
8.6e-5 |
SMART |
|
low complexity region
|
154 |
167 |
N/A |
INTRINSIC |
|
PTPc_DSPc
|
241 |
363 |
9.9e-6 |
SMART |
|
PTEN_C2
|
350 |
477 |
5.6e-56 |
SMART |
|
low complexity region
|
822 |
833 |
N/A |
INTRINSIC |
|
low complexity region
|
905 |
922 |
N/A |
INTRINSIC |
|
low complexity region
|
1206 |
1218 |
N/A |
INTRINSIC |
|
low complexity region
|
1263 |
1279 |
N/A |
INTRINSIC |
|
low complexity region
|
1438 |
1449 |
N/A |
INTRINSIC |
|
low complexity region
|
1497 |
1509 |
N/A |
INTRINSIC |
|
SH2
|
1593 |
1695 |
4.3e-19 |
SMART |
|
PTB
|
1726 |
1867 |
9e-32 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000212888
|
| Meta Mutation Damage Score |
0.1795 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.9%
- 20x: 94.1%
|
| Validation Efficiency |
97% (114/117) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 103 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2810459M11Rik |
C |
A |
1: 85,974,166 (GRCm39) |
T161K |
probably benign |
Het |
| Actn3 |
G |
A |
19: 4,914,539 (GRCm39) |
R530W |
probably damaging |
Het |
| Alg11 |
C |
T |
8: 22,558,026 (GRCm39) |
A404V |
possibly damaging |
Het |
| Alkbh8 |
T |
A |
9: 3,369,751 (GRCm39) |
V340D |
probably damaging |
Het |
| Arhgef12 |
T |
C |
9: 42,886,364 (GRCm39) |
H1166R |
probably benign |
Het |
| Aspm |
T |
A |
1: 139,398,269 (GRCm39) |
D978E |
possibly damaging |
Het |
| Bod1l |
C |
T |
5: 41,975,815 (GRCm39) |
G1833D |
probably damaging |
Het |
| Brd3 |
A |
G |
2: 27,339,251 (GRCm39) |
V676A |
possibly damaging |
Het |
| Brip1 |
G |
A |
11: 86,037,009 (GRCm39) |
T454I |
possibly damaging |
Het |
| C3ar1 |
T |
C |
6: 122,827,723 (GRCm39) |
I165V |
probably benign |
Het |
| Camta1 |
T |
A |
4: 151,228,864 (GRCm39) |
Q656L |
probably benign |
Het |
| Casp14 |
A |
T |
10: 78,549,178 (GRCm39) |
L256* |
probably null |
Het |
| Cdh23 |
G |
T |
10: 60,255,556 (GRCm39) |
H773Q |
possibly damaging |
Het |
| Chd1 |
G |
T |
17: 15,989,016 (GRCm39) |
D1590Y |
probably damaging |
Het |
| Chd1 |
G |
A |
17: 15,989,015 (GRCm39) |
W1589* |
probably null |
Het |
| Cldn19 |
A |
G |
4: 119,112,951 (GRCm39) |
Q61R |
probably damaging |
Het |
| Cyp2a22 |
A |
G |
7: 26,631,949 (GRCm39) |
S436P |
probably benign |
Het |
| Emc10 |
A |
C |
7: 44,142,051 (GRCm39) |
V124G |
probably damaging |
Het |
| Enam |
A |
T |
5: 88,650,885 (GRCm39) |
D723V |
probably benign |
Het |
| Eps8 |
C |
A |
6: 137,504,128 (GRCm39) |
Q158H |
probably damaging |
Het |
| Ercc6 |
G |
A |
14: 32,263,253 (GRCm39) |
D486N |
probably damaging |
Het |
| Fasn |
T |
C |
11: 120,703,885 (GRCm39) |
E1485G |
possibly damaging |
Het |
| Fat2 |
T |
C |
11: 55,169,844 (GRCm39) |
K2972E |
probably benign |
Het |
| Fbxw28 |
T |
C |
9: 109,168,602 (GRCm39) |
K30R |
probably null |
Het |
| Flot2 |
T |
A |
11: 77,948,339 (GRCm39) |
L164Q |
probably damaging |
Het |
| Fsip2 |
A |
T |
2: 82,779,739 (GRCm39) |
I162L |
probably benign |
Het |
| Fsip2 |
A |
T |
2: 82,815,815 (GRCm39) |
L3849F |
probably benign |
Het |
| Gabrb1 |
C |
G |
5: 71,858,154 (GRCm39) |
P60R |
probably damaging |
Het |
| Galnt14 |
T |
C |
17: 73,811,893 (GRCm39) |
R443G |
probably benign |
Het |
| Gas8 |
C |
T |
8: 124,257,753 (GRCm39) |
T400M |
probably benign |
Het |
| Gfap |
T |
C |
11: 102,785,214 (GRCm39) |
Y254C |
probably damaging |
Het |
| Git2 |
A |
G |
5: 114,883,543 (GRCm39) |
S396P |
probably damaging |
Het |
| Glb1l3 |
A |
T |
9: 26,740,349 (GRCm39) |
M327K |
probably benign |
Het |
| Gm10715 |
A |
C |
9: 3,038,062 (GRCm39) |
|
probably benign |
Het |
| Gm10787 |
G |
A |
10: 76,857,841 (GRCm39) |
|
noncoding transcript |
Het |
| Gm1123 |
T |
A |
9: 98,900,622 (GRCm39) |
D78V |
probably damaging |
Het |
| Gm27013 |
T |
C |
6: 130,655,079 (GRCm39) |
T128A |
probably benign |
Het |
| Gpbp1 |
A |
G |
13: 111,577,164 (GRCm39) |
|
probably null |
Het |
| Gphn |
G |
A |
12: 78,569,729 (GRCm39) |
|
probably null |
Het |
| Gpr157 |
A |
G |
4: 150,186,823 (GRCm39) |
E317G |
probably benign |
Het |
| Gsdmc4 |
T |
A |
15: 63,765,596 (GRCm39) |
M318L |
probably benign |
Het |
| Gtf2f2 |
A |
T |
14: 76,248,131 (GRCm39) |
W19R |
probably damaging |
Het |
| Gvin-ps3 |
T |
C |
7: 105,680,627 (GRCm39) |
|
noncoding transcript |
Het |
| Helb |
A |
G |
10: 119,920,763 (GRCm39) |
V1060A |
probably benign |
Het |
| Igfn1 |
C |
T |
1: 135,895,778 (GRCm39) |
G1596D |
probably benign |
Het |
| Il1rl2 |
T |
C |
1: 40,366,547 (GRCm39) |
I27T |
possibly damaging |
Het |
| Inpp5j |
A |
G |
11: 3,449,676 (GRCm39) |
V702A |
probably damaging |
Het |
| Kmt2d |
A |
C |
15: 98,759,775 (GRCm39) |
V1161G |
unknown |
Het |
| Krtap1-3 |
T |
G |
11: 99,481,715 (GRCm39) |
Y144S |
possibly damaging |
Het |
| Layn |
C |
T |
9: 50,968,682 (GRCm39) |
V354M |
probably damaging |
Het |
| Lrba |
G |
A |
3: 86,526,816 (GRCm39) |
|
probably null |
Het |
| Lrp8 |
T |
A |
4: 107,727,234 (GRCm39) |
L893Q |
possibly damaging |
Het |
| Mrps9 |
T |
A |
1: 42,937,575 (GRCm39) |
|
probably benign |
Het |
| Mug1 |
T |
A |
6: 121,862,813 (GRCm39) |
M1387K |
probably damaging |
Het |
| Myo18b |
A |
C |
5: 113,021,895 (GRCm39) |
V499G |
probably benign |
Het |
| Nbea |
T |
C |
3: 55,618,091 (GRCm39) |
E2321G |
probably benign |
Het |
| Nrsn2 |
C |
T |
2: 152,211,552 (GRCm39) |
V160I |
probably benign |
Het |
| Nup210 |
G |
A |
6: 91,008,650 (GRCm39) |
Q510* |
probably null |
Het |
| Ofcc1 |
G |
A |
13: 40,168,864 (GRCm39) |
T841I |
probably damaging |
Het |
| Or2ag12 |
T |
G |
7: 106,277,330 (GRCm39) |
D121A |
probably damaging |
Het |
| P3h3 |
G |
T |
6: 124,827,600 (GRCm39) |
Q479K |
possibly damaging |
Het |
| Paqr9 |
T |
A |
9: 95,442,723 (GRCm39) |
F238I |
probably damaging |
Het |
| Parp3 |
A |
T |
9: 106,350,308 (GRCm39) |
L343H |
probably damaging |
Het |
| Pcdh18 |
A |
C |
3: 49,699,117 (GRCm39) |
M1115R |
probably damaging |
Het |
| Pcdh8 |
A |
G |
14: 80,008,308 (GRCm39) |
V85A |
possibly damaging |
Het |
| Pcdhb4 |
A |
G |
18: 37,441,452 (GRCm39) |
N254S |
possibly damaging |
Het |
| Pld1 |
T |
C |
3: 28,130,700 (GRCm39) |
V500A |
probably benign |
Het |
| Pramel29 |
T |
C |
4: 143,935,144 (GRCm39) |
K199R |
probably damaging |
Het |
| Prkg2 |
A |
T |
5: 99,129,002 (GRCm39) |
D311E |
probably benign |
Het |
| Prss42 |
T |
C |
9: 110,628,369 (GRCm39) |
L171P |
probably damaging |
Het |
| Pth2 |
T |
A |
7: 44,830,767 (GRCm39) |
L17H |
probably damaging |
Het |
| Reln |
A |
T |
5: 22,223,844 (GRCm39) |
|
probably null |
Het |
| Rmi2 |
G |
T |
16: 10,657,701 (GRCm39) |
V104L |
probably damaging |
Het |
| Rpusd4 |
T |
A |
9: 35,179,831 (GRCm39) |
V108D |
probably damaging |
Het |
| Scimp |
G |
A |
11: 70,682,294 (GRCm39) |
Q141* |
probably null |
Het |
| Sel1l2 |
T |
C |
2: 140,105,390 (GRCm39) |
T267A |
probably benign |
Het |
| Sema5a |
T |
A |
15: 32,550,400 (GRCm39) |
S146R |
possibly damaging |
Het |
| Sh2d3c |
T |
C |
2: 32,611,172 (GRCm39) |
M1T |
probably null |
Het |
| Slc30a6 |
T |
C |
17: 74,712,716 (GRCm39) |
L71P |
probably damaging |
Het |
| Srrm3 |
A |
G |
5: 135,883,449 (GRCm39) |
Y224C |
possibly damaging |
Het |
| Tacr3 |
A |
T |
3: 134,560,615 (GRCm39) |
T185S |
possibly damaging |
Het |
| Tas2r140 |
T |
A |
6: 133,032,528 (GRCm39) |
T77S |
probably benign |
Het |
| Thsd7b |
T |
C |
1: 129,523,581 (GRCm39) |
V128A |
probably benign |
Het |
| Tnfrsf10b |
T |
G |
14: 70,013,608 (GRCm39) |
H179Q |
probably damaging |
Het |
| Tonsl |
A |
G |
15: 76,517,409 (GRCm39) |
V770A |
probably benign |
Het |
| Trim42 |
G |
A |
9: 97,244,982 (GRCm39) |
P606L |
probably benign |
Het |
| Trim45 |
A |
T |
3: 100,832,804 (GRCm39) |
T346S |
possibly damaging |
Het |
| Ttc28 |
C |
A |
5: 111,433,947 (GRCm39) |
S2296Y |
probably damaging |
Het |
| Ttc41 |
C |
T |
10: 86,566,989 (GRCm39) |
R552C |
probably benign |
Het |
| Tube1 |
A |
G |
10: 39,020,842 (GRCm39) |
N243D |
probably benign |
Het |
| Tvp23b |
G |
T |
11: 62,770,424 (GRCm39) |
|
probably null |
Het |
| Ubxn11 |
T |
A |
4: 133,836,919 (GRCm39) |
I49N |
probably damaging |
Het |
| Usp17le |
T |
A |
7: 104,418,977 (GRCm39) |
E55V |
probably benign |
Het |
| Vmn2r114 |
A |
T |
17: 23,510,353 (GRCm39) |
V709D |
probably damaging |
Het |
| Vmn2r129 |
G |
C |
4: 156,685,733 (GRCm39) |
|
noncoding transcript |
Het |
| Vmn2r23 |
C |
T |
6: 123,690,033 (GRCm39) |
T303M |
probably damaging |
Het |
| Vmn2r60 |
C |
T |
7: 41,785,285 (GRCm39) |
P166S |
probably damaging |
Het |
| Vmn2r83 |
A |
G |
10: 79,313,682 (GRCm39) |
I97V |
possibly damaging |
Het |
| Wbp2nl |
A |
T |
15: 82,198,537 (GRCm39) |
K358M |
possibly damaging |
Het |
| Xpo1 |
T |
A |
11: 23,228,183 (GRCm39) |
I150N |
probably damaging |
Het |
| Zfp113 |
G |
A |
5: 138,143,687 (GRCm39) |
L188F |
probably damaging |
Het |
| Zfp189 |
T |
G |
4: 49,529,984 (GRCm39) |
S362R |
probably damaging |
Het |
| Zfp593os |
A |
G |
4: 133,972,587 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Rufy4 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01617:Rufy4
|
APN |
1 |
74,168,513 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02075:Rufy4
|
APN |
1 |
74,168,518 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02604:Rufy4
|
APN |
1 |
74,173,348 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02606:Rufy4
|
APN |
1 |
74,172,509 (GRCm39) |
splice site |
probably benign |
|
|
IGL02928:Rufy4
|
APN |
1 |
74,168,241 (GRCm39) |
unclassified |
probably benign |
|
|
R0091:Rufy4
|
UTSW |
1 |
74,168,095 (GRCm39) |
unclassified |
probably benign |
|
|
R0507:Rufy4
|
UTSW |
1 |
74,185,875 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0589:Rufy4
|
UTSW |
1 |
74,172,042 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0595:Rufy4
|
UTSW |
1 |
74,180,089 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0742:Rufy4
|
UTSW |
1 |
74,185,875 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1533:Rufy4
|
UTSW |
1 |
74,169,002 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1666:Rufy4
|
UTSW |
1 |
74,186,837 (GRCm39) |
missense |
probably benign |
0.06 |
|
R1668:Rufy4
|
UTSW |
1 |
74,186,837 (GRCm39) |
missense |
probably benign |
0.06 |
|
R1827:Rufy4
|
UTSW |
1 |
74,173,279 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2018:Rufy4
|
UTSW |
1 |
74,180,106 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R2095:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2306:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2307:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2472:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2475:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3022:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3054:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3055:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3056:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3117:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3118:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3236:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3237:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3545:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3546:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3547:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3548:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3767:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3768:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3770:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3816:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3817:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3818:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3819:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3895:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4050:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4091:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4117:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4124:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4125:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4127:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4231:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4233:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4234:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4236:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4254:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4255:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4319:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4320:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4321:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4321:Rufy4
|
UTSW |
1 |
74,171,943 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4322:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4323:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4324:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4360:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4361:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4406:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4408:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4516:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4517:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4520:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4522:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4524:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4531:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4533:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4617:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4661:Rufy4
|
UTSW |
1 |
74,172,266 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4778:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4779:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4897:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4898:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4899:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4915:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4917:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4918:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4997:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5092:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5097:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5189:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5191:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5195:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5196:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5197:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5226:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5227:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5228:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5230:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5372:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5373:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5374:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5375:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5376:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5377:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5378:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5699:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5748:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5750:Rufy4
|
UTSW |
1 |
74,172,068 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5767:Rufy4
|
UTSW |
1 |
74,186,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5865:Rufy4
|
UTSW |
1 |
74,185,914 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6083:Rufy4
|
UTSW |
1 |
74,168,556 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6149:Rufy4
|
UTSW |
1 |
74,186,892 (GRCm39) |
missense |
probably benign |
0.15 |
|
R6279:Rufy4
|
UTSW |
1 |
74,172,383 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6300:Rufy4
|
UTSW |
1 |
74,172,383 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6629:Rufy4
|
UTSW |
1 |
74,171,526 (GRCm39) |
splice site |
probably null |
|
|
R6809:Rufy4
|
UTSW |
1 |
74,172,206 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7179:Rufy4
|
UTSW |
1 |
74,172,035 (GRCm39) |
missense |
probably benign |
0.12 |
|
R7218:Rufy4
|
UTSW |
1 |
74,172,174 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7453:Rufy4
|
UTSW |
1 |
74,168,493 (GRCm39) |
splice site |
probably null |
|
|
R9377:Rufy4
|
UTSW |
1 |
74,171,879 (GRCm39) |
missense |
probably benign |
0.08 |
|
X0023:Rufy4
|
UTSW |
1 |
74,180,208 (GRCm39) |
missense |
probably benign |
0.04 |
|
X0025:Rufy4
|
UTSW |
1 |
74,172,178 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- AAAGGCCTATATGAGCCCTTTC -3'
(R):5'- AGTGAGGTCTTCAGCTGCAG -3'
Sequencing Primer
(F):5'- AAGGCCTATATGAGCCCTTTCTTCTC -3'
(R):5'- CTTCAGCTGCAGGGTGTG -3'
|
| Posted On |
2016-03-01 |
Incidental Mutation