Incidental Mutation 'R7561:Pik3r4'
| ID |
585140 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Pik3r4
|
| Ensembl Gene |
ENSMUSG00000032571 |
| Gene Name |
phosphoinositide-3-kinase regulatory subunit 4 |
| Synonyms |
p150, Vps15 |
| MMRRC Submission |
045654-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R7561 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
9 |
| Chromosomal Location |
105520177-105564856 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 105564446 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Alanine
at position 1347
(T1347A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000067400
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000065778]
[ENSMUST00000098441]
[ENSMUST00000166431]
[ENSMUST00000191268]
|
| AlphaFold |
Q8VD65 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000065778
AA Change: T1347A
PolyPhen 2
Score 0.939 (Sensitivity: 0.80; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000067400
Gene: ENSMUSG00000032571
AA Change: T1347A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Pkinase_Tyr
|
26 |
310 |
1.7e-5 |
PFAM |
|
Pfam:Pkinase
|
26 |
312 |
1.2e-18 |
PFAM |
|
coiled coil region
|
941 |
963 |
N/A |
INTRINSIC |
|
WD40
|
982 |
1021 |
3.99e-8 |
SMART |
|
WD40
|
1031 |
1070 |
6.16e0 |
SMART |
|
WD40
|
1132 |
1169 |
4.58e1 |
SMART |
|
WD40
|
1171 |
1214 |
1.64e2 |
SMART |
|
WD40
|
1228 |
1269 |
2.76e-2 |
SMART |
|
WD40
|
1317 |
1358 |
2.96e-2 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000098441
|
| SMART Domains |
Protein: ENSMUSP00000096040
Gene: ENSMUSG00000043719
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
17 |
N/A |
INTRINSIC |
|
VWA
|
24 |
197 |
4.26e-26 |
SMART |
|
VWA
|
226 |
407 |
1.06e-30 |
SMART |
|
VWA
|
433 |
610 |
5.19e-39 |
SMART |
|
VWA
|
619 |
795 |
3.58e-42 |
SMART |
|
VWA
|
806 |
982 |
6.64e-37 |
SMART |
|
VWA
|
997 |
1175 |
2.7e-37 |
SMART |
|
VWA
|
1184 |
1370 |
3.45e-1 |
SMART |
|
Pfam:Collagen
|
1389 |
1450 |
3.3e-9 |
PFAM |
|
low complexity region
|
1451 |
1475 |
N/A |
INTRINSIC |
|
low complexity region
|
1490 |
1508 |
N/A |
INTRINSIC |
|
low complexity region
|
1602 |
1623 |
N/A |
INTRINSIC |
|
low complexity region
|
1698 |
1724 |
N/A |
INTRINSIC |
|
VWA
|
1754 |
1937 |
1.73e-17 |
SMART |
|
VWA
|
1962 |
2145 |
4.4e-19 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000166431
|
| SMART Domains |
Protein: ENSMUSP00000125765
Gene: ENSMUSG00000043719
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
17 |
N/A |
INTRINSIC |
|
VWA
|
24 |
197 |
4.26e-26 |
SMART |
|
VWA
|
226 |
407 |
1.06e-30 |
SMART |
|
VWA
|
433 |
610 |
5.19e-39 |
SMART |
|
VWA
|
619 |
795 |
3.58e-42 |
SMART |
|
VWA
|
806 |
982 |
6.64e-37 |
SMART |
|
VWA
|
997 |
1175 |
2.7e-37 |
SMART |
|
VWA
|
1184 |
1370 |
3.45e-1 |
SMART |
|
Pfam:Collagen
|
1389 |
1450 |
9.3e-10 |
PFAM |
|
low complexity region
|
1451 |
1475 |
N/A |
INTRINSIC |
|
low complexity region
|
1490 |
1508 |
N/A |
INTRINSIC |
|
low complexity region
|
1602 |
1623 |
N/A |
INTRINSIC |
|
low complexity region
|
1698 |
1724 |
N/A |
INTRINSIC |
|
VWA
|
1754 |
1937 |
1.73e-17 |
SMART |
|
VWA
|
1962 |
2145 |
4.4e-19 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000191268
AA Change: T1347A
PolyPhen 2
Score 0.939 (Sensitivity: 0.80; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000139427
Gene: ENSMUSG00000032571
AA Change: T1347A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Pkinase_Tyr
|
26 |
310 |
8.9e-7 |
PFAM |
|
Pfam:Pkinase
|
26 |
312 |
3.7e-23 |
PFAM |
|
coiled coil region
|
941 |
963 |
N/A |
INTRINSIC |
|
WD40
|
982 |
1021 |
3.99e-8 |
SMART |
|
WD40
|
1031 |
1070 |
6.16e0 |
SMART |
|
WD40
|
1132 |
1169 |
4.58e1 |
SMART |
|
WD40
|
1171 |
1214 |
1.64e2 |
SMART |
|
WD40
|
1228 |
1269 |
2.76e-2 |
SMART |
|
WD40
|
1317 |
1358 |
2.96e-2 |
SMART |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.7%
- 20x: 99.1%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a knock-out allele exhibit earl embryonic lethality before E7.5. Mice homozygous for a conditional allele activated in muscles exhibit symptoms of autophagic vacuolar myopathies. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 80 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2210408I21Rik |
C |
A |
13: 77,341,314 (GRCm39) |
N314K |
probably benign |
Het |
| A430005L14Rik |
T |
A |
4: 154,045,097 (GRCm39) |
I80N |
probably benign |
Het |
| Abca2 |
A |
G |
2: 25,336,707 (GRCm39) |
H2271R |
probably damaging |
Het |
| Acad8 |
T |
C |
9: 26,890,538 (GRCm39) |
I257V |
probably benign |
Het |
| Acot12 |
A |
T |
13: 91,918,243 (GRCm39) |
T179S |
probably damaging |
Het |
| Adcy10 |
A |
G |
1: 165,386,741 (GRCm39) |
R1155G |
possibly damaging |
Het |
| Adcy9 |
C |
T |
16: 4,236,028 (GRCm39) |
C461Y |
probably damaging |
Het |
| Adgrf1 |
G |
A |
17: 43,622,000 (GRCm39) |
V746I |
possibly damaging |
Het |
| Agbl1 |
C |
A |
7: 76,348,509 (GRCm39) |
Q869K |
unknown |
Het |
| AI837181 |
T |
G |
19: 5,476,491 (GRCm39) |
V218G |
probably damaging |
Het |
| Alg9 |
T |
C |
9: 50,754,074 (GRCm39) |
S585P |
possibly damaging |
Het |
| Arhgef38 |
T |
C |
3: 132,866,489 (GRCm39) |
Q216R |
|
Het |
| Asb4 |
A |
T |
6: 5,430,968 (GRCm39) |
H401L |
possibly damaging |
Het |
| Atg7 |
G |
T |
6: 114,650,002 (GRCm39) |
A60S |
possibly damaging |
Het |
| Atp10a |
T |
A |
7: 58,476,881 (GRCm39) |
C1199S |
probably damaging |
Het |
| Blm |
G |
A |
7: 80,152,276 (GRCm39) |
A557V |
probably damaging |
Het |
| Cbln1 |
A |
T |
8: 88,198,624 (GRCm39) |
M82K |
probably benign |
Het |
| Ccdc183 |
T |
G |
2: 25,501,529 (GRCm39) |
I293L |
probably benign |
Het |
| Col6a3 |
A |
G |
1: 90,703,463 (GRCm39) |
S3035P |
unknown |
Het |
| Cux2 |
A |
T |
5: 122,017,931 (GRCm39) |
S206T |
probably benign |
Het |
| Cyfip2 |
T |
C |
11: 46,161,425 (GRCm39) |
D355G |
probably benign |
Het |
| Dhrs2 |
A |
G |
14: 55,474,698 (GRCm39) |
H111R |
probably benign |
Het |
| Eif3b |
T |
G |
5: 140,428,109 (GRCm39) |
D781E |
probably benign |
Het |
| Enpp5 |
G |
A |
17: 44,396,155 (GRCm39) |
G356S |
probably damaging |
Het |
| Fermt1 |
A |
T |
2: 132,758,008 (GRCm39) |
I469N |
probably benign |
Het |
| Fgf20 |
G |
T |
8: 40,732,975 (GRCm39) |
N154K |
possibly damaging |
Het |
| Fndc10 |
T |
A |
4: 155,779,328 (GRCm39) |
V124E |
probably damaging |
Het |
| Fra10ac1 |
T |
C |
19: 38,210,324 (GRCm39) |
D13G |
probably damaging |
Het |
| Gpatch1 |
A |
G |
7: 35,008,800 (GRCm39) |
S74P |
probably damaging |
Het |
| Gramd1b |
G |
A |
9: 40,312,911 (GRCm39) |
T19I |
unknown |
Het |
| Grm8 |
T |
C |
6: 27,429,524 (GRCm39) |
T457A |
probably benign |
Het |
| Gucy2g |
C |
A |
19: 55,194,772 (GRCm39) |
V882L |
probably benign |
Het |
| Hectd4 |
G |
A |
5: 121,429,288 (GRCm39) |
R811H |
possibly damaging |
Het |
| Hk1 |
C |
T |
10: 62,116,807 (GRCm39) |
|
probably null |
Het |
| Idh2 |
TCCCAGG |
T |
7: 79,748,079 (GRCm39) |
|
probably benign |
Het |
| Il10ra |
T |
A |
9: 45,167,117 (GRCm39) |
D480V |
probably benign |
Het |
| Il18rap |
A |
T |
1: 40,563,537 (GRCm39) |
H22L |
probably benign |
Het |
| Inpp5a |
T |
A |
7: 139,147,338 (GRCm39) |
I321N |
probably damaging |
Het |
| Insyn1 |
A |
G |
9: 58,406,687 (GRCm39) |
D199G |
probably damaging |
Het |
| Kat2b |
T |
G |
17: 53,948,286 (GRCm39) |
L352R |
probably benign |
Het |
| Katnip |
C |
T |
7: 125,441,894 (GRCm39) |
S627L |
probably benign |
Het |
| Kcna1 |
A |
T |
6: 126,619,108 (GRCm39) |
V404E |
probably damaging |
Het |
| Mcm3ap |
T |
A |
10: 76,328,712 (GRCm39) |
V1110E |
possibly damaging |
Het |
| Moxd2 |
C |
T |
6: 40,864,337 (GRCm39) |
R31H |
probably damaging |
Het |
| Mpdz |
A |
T |
4: 81,225,388 (GRCm39) |
N1368K |
probably damaging |
Het |
| Mpzl3 |
G |
T |
9: 44,966,610 (GRCm39) |
V24F |
probably benign |
Het |
| Mybph |
G |
A |
1: 134,121,465 (GRCm39) |
|
probably null |
Het |
| Ncam1 |
G |
T |
9: 49,476,242 (GRCm39) |
D282E |
probably damaging |
Het |
| Ntrk2 |
G |
A |
13: 59,009,202 (GRCm39) |
C331Y |
probably benign |
Het |
| Nwd2 |
T |
A |
5: 63,964,434 (GRCm39) |
C1339* |
probably null |
Het |
| Or3a1d |
T |
C |
11: 74,238,436 (GRCm39) |
|
probably benign |
Het |
| Or5b98 |
T |
C |
19: 12,931,403 (GRCm39) |
V150A |
probably benign |
Het |
| Or8k33 |
T |
C |
2: 86,383,661 (GRCm39) |
D269G |
probably benign |
Het |
| Osbpl6 |
C |
A |
2: 76,416,498 (GRCm39) |
T672N |
probably damaging |
Het |
| Pds5b |
T |
C |
5: 150,662,783 (GRCm39) |
|
probably null |
Het |
| Perm1 |
A |
G |
4: 156,303,217 (GRCm39) |
N587S |
probably benign |
Het |
| Pex7 |
A |
T |
10: 19,770,012 (GRCm39) |
C165* |
probably null |
Het |
| Pitpnm3 |
T |
C |
11: 71,942,008 (GRCm39) |
D933G |
probably benign |
Het |
| Rnf213 |
T |
A |
11: 119,332,545 (GRCm39) |
F2586I |
|
Het |
| Scn10a |
A |
G |
9: 119,523,390 (GRCm39) |
M1T |
probably null |
Het |
| Sdhaf3 |
T |
A |
6: 6,956,079 (GRCm39) |
L18Q |
not run |
Het |
| Septin7 |
A |
G |
9: 25,209,151 (GRCm39) |
E256G |
possibly damaging |
Het |
| Slc35b2 |
A |
G |
17: 45,877,727 (GRCm39) |
T236A |
probably damaging |
Het |
| Slc4a4 |
G |
A |
5: 89,347,556 (GRCm39) |
G766R |
probably damaging |
Het |
| Slco6c1 |
G |
T |
1: 97,000,691 (GRCm39) |
S537Y |
probably damaging |
Het |
| Srp68 |
T |
C |
11: 116,139,593 (GRCm39) |
E452G |
probably damaging |
Het |
| Taf2 |
A |
T |
15: 54,919,229 (GRCm39) |
M382K |
probably benign |
Het |
| Tas2r131 |
A |
G |
6: 132,933,921 (GRCm39) |
L296P |
probably benign |
Het |
| Tlr9 |
A |
G |
9: 106,103,148 (GRCm39) |
E813G |
probably benign |
Het |
| Trmt44 |
T |
C |
5: 35,715,336 (GRCm39) |
E659G |
possibly damaging |
Het |
| Ttc21b |
G |
A |
2: 66,047,548 (GRCm39) |
A849V |
possibly damaging |
Het |
| Unc45a |
G |
T |
7: 79,981,334 (GRCm39) |
S489R |
possibly damaging |
Het |
| Xrn1 |
T |
C |
9: 95,881,511 (GRCm39) |
V795A |
probably benign |
Het |
| Zbtb22 |
A |
T |
17: 34,136,952 (GRCm39) |
T366S |
probably benign |
Het |
| Zcchc10 |
T |
A |
11: 53,215,545 (GRCm39) |
H6Q |
probably benign |
Het |
| Zfp60 |
A |
G |
7: 27,447,955 (GRCm39) |
K208E |
probably damaging |
Het |
| Zfp780b |
A |
T |
7: 27,664,037 (GRCm39) |
C173S |
possibly damaging |
Het |
| Zfp786 |
C |
A |
6: 47,796,667 (GRCm39) |
R757L |
probably benign |
Het |
| Zfp936 |
G |
A |
7: 42,839,339 (GRCm39) |
A269T |
probably damaging |
Het |
| Zfp976 |
T |
C |
7: 42,265,701 (GRCm39) |
Y29C |
probably damaging |
Het |
|
| Other mutations in Pik3r4 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01375:Pik3r4
|
APN |
9 |
105,521,803 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
IGL01617:Pik3r4
|
APN |
9 |
105,532,164 (GRCm39) |
missense |
probably benign |
0.33 |
|
IGL01764:Pik3r4
|
APN |
9 |
105,562,321 (GRCm39) |
splice site |
probably benign |
|
|
IGL01817:Pik3r4
|
APN |
9 |
105,528,021 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01830:Pik3r4
|
APN |
9 |
105,522,154 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01905:Pik3r4
|
APN |
9 |
105,522,077 (GRCm39) |
nonsense |
probably null |
|
|
IGL01947:Pik3r4
|
APN |
9 |
105,563,349 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL01985:Pik3r4
|
APN |
9 |
105,540,244 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02321:Pik3r4
|
APN |
9 |
105,521,677 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02389:Pik3r4
|
APN |
9 |
105,527,530 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
IGL02898:Pik3r4
|
APN |
9 |
105,527,605 (GRCm39) |
missense |
probably benign |
0.21 |
|
IGL03037:Pik3r4
|
APN |
9 |
105,528,012 (GRCm39) |
missense |
probably damaging |
1.00 |
|
boteh
|
UTSW |
9 |
105,545,137 (GRCm39) |
splice site |
probably null |
|
|
truth
|
UTSW |
9 |
105,527,805 (GRCm39) |
missense |
probably damaging |
0.98 |
|
verisimilitude
|
UTSW |
9 |
105,555,352 (GRCm39) |
missense |
probably benign |
0.17 |
|
IGL02835:Pik3r4
|
UTSW |
9 |
105,549,905 (GRCm39) |
missense |
probably benign |
0.07 |
|
R0011:Pik3r4
|
UTSW |
9 |
105,521,836 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0312:Pik3r4
|
UTSW |
9 |
105,563,409 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0321:Pik3r4
|
UTSW |
9 |
105,525,906 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0482:Pik3r4
|
UTSW |
9 |
105,546,244 (GRCm39) |
missense |
probably benign |
0.04 |
|
R0645:Pik3r4
|
UTSW |
9 |
105,546,386 (GRCm39) |
splice site |
probably benign |
|
|
R0690:Pik3r4
|
UTSW |
9 |
105,531,175 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R0789:Pik3r4
|
UTSW |
9 |
105,562,366 (GRCm39) |
missense |
probably benign |
0.14 |
|
R0894:Pik3r4
|
UTSW |
9 |
105,544,970 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R0988:Pik3r4
|
UTSW |
9 |
105,564,404 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1123:Pik3r4
|
UTSW |
9 |
105,540,328 (GRCm39) |
missense |
probably benign |
|
|
R1172:Pik3r4
|
UTSW |
9 |
105,540,373 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1174:Pik3r4
|
UTSW |
9 |
105,540,373 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1342:Pik3r4
|
UTSW |
9 |
105,528,100 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1387:Pik3r4
|
UTSW |
9 |
105,521,490 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1480:Pik3r4
|
UTSW |
9 |
105,564,443 (GRCm39) |
missense |
probably benign |
0.39 |
|
R1638:Pik3r4
|
UTSW |
9 |
105,564,408 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1643:Pik3r4
|
UTSW |
9 |
105,564,351 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R1995:Pik3r4
|
UTSW |
9 |
105,546,364 (GRCm39) |
missense |
probably benign |
0.12 |
|
R2037:Pik3r4
|
UTSW |
9 |
105,527,534 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2165:Pik3r4
|
UTSW |
9 |
105,549,984 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4210:Pik3r4
|
UTSW |
9 |
105,527,957 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R4515:Pik3r4
|
UTSW |
9 |
105,549,924 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4519:Pik3r4
|
UTSW |
9 |
105,549,924 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4630:Pik3r4
|
UTSW |
9 |
105,532,098 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4632:Pik3r4
|
UTSW |
9 |
105,532,098 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4732:Pik3r4
|
UTSW |
9 |
105,555,375 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R4733:Pik3r4
|
UTSW |
9 |
105,555,375 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R4940:Pik3r4
|
UTSW |
9 |
105,546,193 (GRCm39) |
missense |
probably benign |
0.20 |
|
R5120:Pik3r4
|
UTSW |
9 |
105,546,208 (GRCm39) |
missense |
probably benign |
0.30 |
|
R5169:Pik3r4
|
UTSW |
9 |
105,555,360 (GRCm39) |
missense |
probably benign |
0.14 |
|
R5183:Pik3r4
|
UTSW |
9 |
105,559,507 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R5353:Pik3r4
|
UTSW |
9 |
105,545,137 (GRCm39) |
splice site |
probably null |
|
|
R5463:Pik3r4
|
UTSW |
9 |
105,525,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5635:Pik3r4
|
UTSW |
9 |
105,545,024 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5763:Pik3r4
|
UTSW |
9 |
105,546,974 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5830:Pik3r4
|
UTSW |
9 |
105,522,023 (GRCm39) |
nonsense |
probably null |
|
|
R6251:Pik3r4
|
UTSW |
9 |
105,531,247 (GRCm39) |
missense |
probably benign |
|
|
R6468:Pik3r4
|
UTSW |
9 |
105,562,389 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R6611:Pik3r4
|
UTSW |
9 |
105,521,476 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6642:Pik3r4
|
UTSW |
9 |
105,521,845 (GRCm39) |
missense |
probably benign |
0.11 |
|
R6821:Pik3r4
|
UTSW |
9 |
105,527,805 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7039:Pik3r4
|
UTSW |
9 |
105,554,089 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R7144:Pik3r4
|
UTSW |
9 |
105,527,783 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7410:Pik3r4
|
UTSW |
9 |
105,527,790 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7559:Pik3r4
|
UTSW |
9 |
105,555,352 (GRCm39) |
missense |
probably benign |
0.17 |
|
R7658:Pik3r4
|
UTSW |
9 |
105,521,710 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7727:Pik3r4
|
UTSW |
9 |
105,547,081 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7871:Pik3r4
|
UTSW |
9 |
105,540,316 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7957:Pik3r4
|
UTSW |
9 |
105,564,408 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8138:Pik3r4
|
UTSW |
9 |
105,546,234 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R8686:Pik3r4
|
UTSW |
9 |
105,535,728 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R8719:Pik3r4
|
UTSW |
9 |
105,559,394 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9091:Pik3r4
|
UTSW |
9 |
105,547,108 (GRCm39) |
missense |
probably benign |
0.35 |
|
R9189:Pik3r4
|
UTSW |
9 |
105,547,038 (GRCm39) |
missense |
probably benign |
0.22 |
|
R9270:Pik3r4
|
UTSW |
9 |
105,547,108 (GRCm39) |
missense |
probably benign |
0.35 |
|
R9439:Pik3r4
|
UTSW |
9 |
105,528,041 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AATGAGGCGCAGGTTTAACC -3'
(R):5'- TGCACATGAAGAAAGTCACCATG -3'
Sequencing Primer
(F):5'- AACCTCAGGCCTTTGTTTTTGAC -3'
(R):5'- TGAAGAAAGTCACCATGCCTAC -3'
|
| Posted On |
2019-10-17 |
Incidental Mutation