Incidental Mutation 'R8007:Foxp1'
| ID |
616685 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Foxp1
|
| Ensembl Gene |
ENSMUSG00000030067 |
| Gene Name |
forkhead box P1 |
| Synonyms |
3110052D19Rik, 4932443N09Rik |
| MMRRC Submission |
046047-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R8007 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
6 |
| Chromosomal Location |
98902299-99499682 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 98918595 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Arginine
at position 514
(S514R)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000108952
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000074346]
[ENSMUST00000113322]
[ENSMUST00000113324]
[ENSMUST00000113326]
[ENSMUST00000113328]
[ENSMUST00000113329]
[ENSMUST00000124058]
[ENSMUST00000176565]
[ENSMUST00000176632]
[ENSMUST00000176850]
[ENSMUST00000177229]
[ENSMUST00000177230]
[ENSMUST00000177307]
[ENSMUST00000177437]
|
| AlphaFold |
P58462 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000074346
AA Change: S546R
PolyPhen 2
Score 0.856 (Sensitivity: 0.83; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000073953
Gene: ENSMUSG00000030067
AA Change: S546R
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
62 |
113 |
N/A |
INTRINSIC |
|
low complexity region
|
140 |
191 |
N/A |
INTRINSIC |
|
low complexity region
|
200 |
233 |
N/A |
INTRINSIC |
|
low complexity region
|
236 |
250 |
N/A |
INTRINSIC |
|
low complexity region
|
264 |
275 |
N/A |
INTRINSIC |
|
low complexity region
|
317 |
330 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
334 |
359 |
8.67e-1 |
SMART |
|
low complexity region
|
371 |
383 |
N/A |
INTRINSIC |
|
low complexity region
|
432 |
446 |
N/A |
INTRINSIC |
|
FH
|
491 |
572 |
2.07e-39 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000113322
AA Change: S546R
PolyPhen 2
Score 0.856 (Sensitivity: 0.83; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000108948
Gene: ENSMUSG00000030067
AA Change: S546R
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
62 |
113 |
N/A |
INTRINSIC |
|
low complexity region
|
140 |
191 |
N/A |
INTRINSIC |
|
low complexity region
|
200 |
233 |
N/A |
INTRINSIC |
|
low complexity region
|
236 |
250 |
N/A |
INTRINSIC |
|
low complexity region
|
264 |
275 |
N/A |
INTRINSIC |
|
low complexity region
|
317 |
330 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
334 |
359 |
8.67e-1 |
SMART |
|
low complexity region
|
371 |
383 |
N/A |
INTRINSIC |
|
low complexity region
|
432 |
446 |
N/A |
INTRINSIC |
|
FH
|
491 |
572 |
2.07e-39 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000113324
AA Change: S547R
PolyPhen 2
Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000108950
Gene: ENSMUSG00000030067
AA Change: S547R
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
62 |
113 |
N/A |
INTRINSIC |
|
low complexity region
|
140 |
192 |
N/A |
INTRINSIC |
|
low complexity region
|
201 |
234 |
N/A |
INTRINSIC |
|
low complexity region
|
237 |
251 |
N/A |
INTRINSIC |
|
low complexity region
|
265 |
276 |
N/A |
INTRINSIC |
|
low complexity region
|
318 |
331 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
335 |
360 |
8.67e-1 |
SMART |
|
low complexity region
|
372 |
384 |
N/A |
INTRINSIC |
|
low complexity region
|
433 |
447 |
N/A |
INTRINSIC |
|
FH
|
492 |
573 |
2.07e-39 |
SMART |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000113326
AA Change: S514R
|
| SMART Domains |
Protein: ENSMUSP00000108952
Gene: ENSMUSG00000030067
AA Change: S514R
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
108 |
159 |
N/A |
INTRINSIC |
|
low complexity region
|
168 |
201 |
N/A |
INTRINSIC |
|
low complexity region
|
204 |
218 |
N/A |
INTRINSIC |
|
low complexity region
|
232 |
243 |
N/A |
INTRINSIC |
|
low complexity region
|
285 |
298 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
302 |
327 |
8.67e-1 |
SMART |
|
low complexity region
|
339 |
351 |
N/A |
INTRINSIC |
|
low complexity region
|
400 |
414 |
N/A |
INTRINSIC |
|
FH
|
459 |
540 |
2.07e-39 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000113328
AA Change: S547R
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000108954
Gene: ENSMUSG00000030067
AA Change: S547R
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
62 |
113 |
N/A |
INTRINSIC |
|
low complexity region
|
140 |
191 |
N/A |
INTRINSIC |
|
low complexity region
|
200 |
234 |
N/A |
INTRINSIC |
|
low complexity region
|
237 |
251 |
N/A |
INTRINSIC |
|
low complexity region
|
265 |
276 |
N/A |
INTRINSIC |
|
low complexity region
|
318 |
331 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
335 |
360 |
8.67e-1 |
SMART |
|
low complexity region
|
372 |
384 |
N/A |
INTRINSIC |
|
low complexity region
|
433 |
447 |
N/A |
INTRINSIC |
|
FH
|
492 |
573 |
2.07e-39 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113329
|
| SMART Domains |
Protein: ENSMUSP00000108955
Gene: ENSMUSG00000030067
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
62 |
113 |
N/A |
INTRINSIC |
|
low complexity region
|
140 |
191 |
N/A |
INTRINSIC |
|
low complexity region
|
200 |
233 |
N/A |
INTRINSIC |
|
low complexity region
|
236 |
250 |
N/A |
INTRINSIC |
|
low complexity region
|
264 |
275 |
N/A |
INTRINSIC |
|
low complexity region
|
317 |
330 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
334 |
359 |
8.67e-1 |
SMART |
|
low complexity region
|
371 |
383 |
N/A |
INTRINSIC |
|
low complexity region
|
432 |
446 |
N/A |
INTRINSIC |
|
FH
|
491 |
579 |
1.76e-10 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000124058
|
| SMART Domains |
Protein: ENSMUSP00000120244
Gene: ENSMUSG00000030067
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
10 |
62 |
N/A |
INTRINSIC |
|
low complexity region
|
71 |
104 |
N/A |
INTRINSIC |
|
low complexity region
|
107 |
121 |
N/A |
INTRINSIC |
|
low complexity region
|
135 |
146 |
N/A |
INTRINSIC |
|
low complexity region
|
188 |
201 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
205 |
230 |
8.67e-1 |
SMART |
|
low complexity region
|
242 |
254 |
N/A |
INTRINSIC |
|
low complexity region
|
303 |
317 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000176565
AA Change: S546R
|
| SMART Domains |
Protein: ENSMUSP00000135181
Gene: ENSMUSG00000030067
AA Change: S546R
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
62 |
113 |
N/A |
INTRINSIC |
|
low complexity region
|
140 |
191 |
N/A |
INTRINSIC |
|
low complexity region
|
200 |
234 |
N/A |
INTRINSIC |
|
low complexity region
|
237 |
251 |
N/A |
INTRINSIC |
|
low complexity region
|
265 |
276 |
N/A |
INTRINSIC |
|
low complexity region
|
318 |
331 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
335 |
360 |
8.67e-1 |
SMART |
|
low complexity region
|
372 |
384 |
N/A |
INTRINSIC |
|
low complexity region
|
433 |
447 |
N/A |
INTRINSIC |
|
FH
|
491 |
572 |
2.07e-39 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000176632
AA Change: S515R
PolyPhen 2
Score 0.856 (Sensitivity: 0.83; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000135635
Gene: ENSMUSG00000030067
AA Change: S515R
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
108 |
159 |
N/A |
INTRINSIC |
|
low complexity region
|
168 |
202 |
N/A |
INTRINSIC |
|
low complexity region
|
205 |
219 |
N/A |
INTRINSIC |
|
low complexity region
|
233 |
244 |
N/A |
INTRINSIC |
|
low complexity region
|
286 |
299 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
303 |
328 |
8.67e-1 |
SMART |
|
low complexity region
|
340 |
352 |
N/A |
INTRINSIC |
|
low complexity region
|
401 |
415 |
N/A |
INTRINSIC |
|
FH
|
460 |
541 |
2.07e-39 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000176850
AA Change: S516R
PolyPhen 2
Score 0.987 (Sensitivity: 0.73; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000135041
Gene: ENSMUSG00000030067
AA Change: S516R
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
108 |
160 |
N/A |
INTRINSIC |
|
low complexity region
|
169 |
203 |
N/A |
INTRINSIC |
|
low complexity region
|
206 |
220 |
N/A |
INTRINSIC |
|
low complexity region
|
234 |
245 |
N/A |
INTRINSIC |
|
low complexity region
|
287 |
300 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
304 |
329 |
8.67e-1 |
SMART |
|
low complexity region
|
341 |
353 |
N/A |
INTRINSIC |
|
low complexity region
|
402 |
416 |
N/A |
INTRINSIC |
|
FH
|
461 |
542 |
2.07e-39 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000177229
AA Change: S418R
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000134817
Gene: ENSMUSG00000030067
AA Change: S418R
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
10 |
62 |
N/A |
INTRINSIC |
|
low complexity region
|
71 |
105 |
N/A |
INTRINSIC |
|
low complexity region
|
108 |
122 |
N/A |
INTRINSIC |
|
low complexity region
|
136 |
147 |
N/A |
INTRINSIC |
|
low complexity region
|
189 |
202 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
206 |
231 |
8.67e-1 |
SMART |
|
low complexity region
|
243 |
255 |
N/A |
INTRINSIC |
|
low complexity region
|
304 |
318 |
N/A |
INTRINSIC |
|
FH
|
363 |
444 |
2.07e-39 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000177230
AA Change: S516R
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000135098
Gene: ENSMUSG00000030067
AA Change: S516R
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
108 |
160 |
N/A |
INTRINSIC |
|
low complexity region
|
169 |
203 |
N/A |
INTRINSIC |
|
low complexity region
|
206 |
220 |
N/A |
INTRINSIC |
|
low complexity region
|
234 |
245 |
N/A |
INTRINSIC |
|
low complexity region
|
287 |
300 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
304 |
329 |
8.67e-1 |
SMART |
|
low complexity region
|
341 |
353 |
N/A |
INTRINSIC |
|
low complexity region
|
402 |
416 |
N/A |
INTRINSIC |
|
FH
|
461 |
542 |
2.07e-39 |
SMART |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000177307
AA Change: S547R
|
| SMART Domains |
Protein: ENSMUSP00000135764
Gene: ENSMUSG00000030067
AA Change: S547R
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
62 |
113 |
N/A |
INTRINSIC |
|
low complexity region
|
140 |
192 |
N/A |
INTRINSIC |
|
low complexity region
|
201 |
235 |
N/A |
INTRINSIC |
|
low complexity region
|
238 |
252 |
N/A |
INTRINSIC |
|
low complexity region
|
266 |
277 |
N/A |
INTRINSIC |
|
low complexity region
|
319 |
332 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
336 |
361 |
8.67e-1 |
SMART |
|
low complexity region
|
373 |
385 |
N/A |
INTRINSIC |
|
low complexity region
|
434 |
448 |
N/A |
INTRINSIC |
|
FH
|
492 |
573 |
2.07e-39 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000177437
AA Change: S417R
PolyPhen 2
Score 0.856 (Sensitivity: 0.83; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000135809
Gene: ENSMUSG00000030067
AA Change: S417R
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
10 |
61 |
N/A |
INTRINSIC |
|
low complexity region
|
70 |
104 |
N/A |
INTRINSIC |
|
low complexity region
|
107 |
121 |
N/A |
INTRINSIC |
|
low complexity region
|
135 |
146 |
N/A |
INTRINSIC |
|
low complexity region
|
188 |
201 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
205 |
230 |
8.67e-1 |
SMART |
|
low complexity region
|
242 |
254 |
N/A |
INTRINSIC |
|
low complexity region
|
303 |
317 |
N/A |
INTRINSIC |
|
FH
|
362 |
443 |
2.07e-39 |
SMART |
|
| Meta Mutation Damage Score |
0.9197 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.4%
|
| Validation Efficiency |
100% (62/62) |
| MGI Phenotype |
PHENOTYPE: Homozygous null mice display embryonic lethality with abnormal outflow tract septation, ventricular septal defects, abnormal cardiac valve morphology, decreased and irregular heart rate, thin ventricular compact zone, and edema. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 63 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A2m |
T |
A |
6: 121,647,845 (GRCm39) |
|
probably benign |
Het |
| A430033K04Rik |
T |
C |
5: 138,644,901 (GRCm39) |
I262T |
probably benign |
Het |
| Acacb |
A |
G |
5: 114,356,935 (GRCm39) |
R1289G |
probably damaging |
Het |
| Adgre4 |
A |
T |
17: 56,121,233 (GRCm39) |
H433L |
probably damaging |
Het |
| Adgrv1 |
A |
G |
13: 81,431,585 (GRCm39) |
F5948L |
probably benign |
Het |
| Adtrp |
A |
T |
13: 41,969,707 (GRCm39) |
D97E |
probably damaging |
Het |
| Anapc5 |
T |
C |
5: 122,929,963 (GRCm39) |
T543A |
probably benign |
Het |
| Ank2 |
G |
C |
3: 126,730,096 (GRCm39) |
|
probably benign |
Het |
| Cacna2d4 |
C |
T |
6: 119,289,405 (GRCm39) |
A813V |
probably benign |
Het |
| Cc2d2a |
T |
A |
5: 43,863,442 (GRCm39) |
Y684N |
possibly damaging |
Het |
| Cenpf |
G |
A |
1: 189,379,144 (GRCm39) |
P35L |
|
Het |
| Chtf18 |
A |
G |
17: 25,944,508 (GRCm39) |
F281L |
probably damaging |
Het |
| Clstn1 |
T |
C |
4: 149,716,305 (GRCm39) |
V257A |
probably damaging |
Het |
| Cnmd |
A |
T |
14: 79,875,406 (GRCm39) |
V338E |
probably damaging |
Het |
| Col6a3 |
A |
C |
1: 90,705,179 (GRCm39) |
F2848V |
unknown |
Het |
| Corin |
T |
C |
5: 72,473,446 (GRCm39) |
S888G |
probably damaging |
Het |
| Ctss |
A |
T |
3: 95,457,465 (GRCm39) |
S309C |
probably null |
Het |
| Dmxl2 |
G |
A |
9: 54,290,975 (GRCm39) |
Q2492* |
probably null |
Het |
| Exoc7 |
C |
T |
11: 116,197,465 (GRCm39) |
R12Q |
possibly damaging |
Het |
| F12 |
A |
G |
13: 55,566,265 (GRCm39) |
I509T |
probably damaging |
Het |
| F13b |
A |
G |
1: 139,434,680 (GRCm39) |
K149E |
probably benign |
Het |
| Fasn |
A |
G |
11: 120,700,353 (GRCm39) |
I2159T |
probably benign |
Het |
| Fgfr2 |
A |
T |
7: 129,765,719 (GRCm39) |
Y831* |
probably null |
Het |
| Gm11569 |
A |
G |
11: 99,689,688 (GRCm39) |
S4P |
unknown |
Het |
| Gria4 |
T |
C |
9: 4,503,740 (GRCm39) |
|
probably benign |
Het |
| Hnrnpul2 |
T |
A |
19: 8,798,179 (GRCm39) |
|
probably null |
Het |
| Ibtk |
A |
T |
9: 85,572,770 (GRCm39) |
D1257E |
probably benign |
Het |
| Ip6k2 |
T |
C |
9: 108,682,955 (GRCm39) |
V355A |
probably benign |
Het |
| Kcnd2 |
G |
A |
6: 21,217,073 (GRCm39) |
R259H |
probably damaging |
Het |
| Kcnj2 |
A |
C |
11: 110,963,884 (GRCm39) |
E425D |
probably benign |
Het |
| Ldlrad1 |
G |
A |
4: 107,066,688 (GRCm39) |
A8T |
probably benign |
Het |
| Lgi2 |
C |
A |
5: 52,723,375 (GRCm39) |
A25S |
probably benign |
Het |
| Lrp2 |
T |
C |
2: 69,336,849 (GRCm39) |
T1308A |
probably benign |
Het |
| Ly6g2 |
A |
G |
15: 75,088,552 (GRCm39) |
T7A |
probably benign |
Het |
| Matn2 |
A |
T |
15: 34,426,315 (GRCm39) |
N609I |
probably benign |
Het |
| Mocs2 |
T |
A |
13: 114,957,409 (GRCm39) |
S9T |
possibly damaging |
Het |
| Nebl |
T |
A |
2: 17,375,300 (GRCm39) |
I102F |
|
Het |
| Nudt19 |
A |
G |
7: 35,255,045 (GRCm39) |
V62A |
probably benign |
Het |
| Or10u4 |
T |
A |
10: 129,801,744 (GRCm39) |
D269V |
possibly damaging |
Het |
| Or12k8 |
T |
A |
2: 36,974,855 (GRCm39) |
R302W |
probably damaging |
Het |
| Or4a68 |
C |
T |
2: 89,270,684 (GRCm39) |
|
|
Het |
| Or4k42 |
A |
T |
2: 111,320,068 (GRCm39) |
V145E |
probably damaging |
Het |
| Pacrg |
A |
G |
17: 11,058,919 (GRCm39) |
|
probably benign |
Het |
| Pappa2 |
A |
G |
1: 158,609,874 (GRCm39) |
I1529T |
probably damaging |
Het |
| Pcdhga7 |
A |
T |
18: 37,849,946 (GRCm39) |
H651L |
probably benign |
Het |
| Plch2 |
A |
G |
4: 155,087,288 (GRCm39) |
L321P |
probably damaging |
Het |
| Ppargc1b |
A |
T |
18: 61,443,565 (GRCm39) |
S549T |
possibly damaging |
Het |
| Rtel1 |
T |
A |
2: 180,976,767 (GRCm39) |
N254K |
probably damaging |
Het |
| Rtl1 |
T |
C |
12: 109,558,060 (GRCm39) |
N1260D |
possibly damaging |
Het |
| Samd7 |
T |
A |
3: 30,812,531 (GRCm39) |
W324R |
probably damaging |
Het |
| Serpinb9e |
A |
G |
13: 33,435,605 (GRCm39) |
I13V |
probably benign |
Het |
| Skint10 |
A |
G |
4: 112,568,865 (GRCm39) |
L284S |
possibly damaging |
Het |
| Slc25a38 |
T |
A |
9: 119,951,208 (GRCm39) |
I247K |
possibly damaging |
Het |
| Smarce1 |
G |
C |
11: 99,115,876 (GRCm39) |
N48K |
possibly damaging |
Het |
| Stmn4 |
T |
G |
14: 66,593,032 (GRCm39) |
|
probably benign |
Het |
| Stt3a |
G |
C |
9: 36,653,065 (GRCm39) |
T539R |
probably damaging |
Het |
| Tab1 |
G |
A |
15: 80,042,969 (GRCm39) |
V388I |
possibly damaging |
Het |
| Tcf12 |
G |
C |
9: 71,841,905 (GRCm39) |
|
probably benign |
Het |
| Tcof1 |
G |
C |
18: 60,962,123 (GRCm39) |
A702G |
possibly damaging |
Het |
| Trp53inp1 |
T |
C |
4: 11,164,525 (GRCm39) |
F23S |
probably damaging |
Het |
| Vmn2r14 |
A |
T |
5: 109,368,324 (GRCm39) |
L223M |
probably benign |
Het |
| Yae1d1 |
G |
A |
13: 18,164,329 (GRCm39) |
S96L |
probably damaging |
Het |
| Zfp142 |
T |
C |
1: 74,610,655 (GRCm39) |
I1047V |
probably benign |
Het |
|
| Other mutations in Foxp1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL02191:Foxp1
|
APN |
6 |
98,922,561 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02330:Foxp1
|
APN |
6 |
98,922,373 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02869:Foxp1
|
APN |
6 |
98,907,044 (GRCm39) |
utr 3 prime |
probably benign |
|
|
IGL02968:Foxp1
|
APN |
6 |
99,052,822 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Foxy
|
UTSW |
6 |
98,992,471 (GRCm39) |
nonsense |
probably null |
|
|
Moxie
|
UTSW |
6 |
98,992,475 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
Roxie
|
UTSW |
6 |
98,918,595 (GRCm39) |
missense |
unknown |
|
|
R0037:Foxp1
|
UTSW |
6 |
99,139,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0063:Foxp1
|
UTSW |
6 |
98,921,684 (GRCm39) |
splice site |
probably benign |
|
|
R0063:Foxp1
|
UTSW |
6 |
98,921,684 (GRCm39) |
splice site |
probably benign |
|
|
R0427:Foxp1
|
UTSW |
6 |
98,907,164 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0601:Foxp1
|
UTSW |
6 |
98,907,083 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1356:Foxp1
|
UTSW |
6 |
98,993,637 (GRCm39) |
splice site |
probably benign |
|
|
R1468:Foxp1
|
UTSW |
6 |
98,955,181 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R1468:Foxp1
|
UTSW |
6 |
98,955,181 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R1548:Foxp1
|
UTSW |
6 |
98,922,381 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1696:Foxp1
|
UTSW |
6 |
98,922,663 (GRCm39) |
missense |
probably benign |
0.18 |
|
R1933:Foxp1
|
UTSW |
6 |
99,052,926 (GRCm39) |
small deletion |
probably benign |
|
|
R2152:Foxp1
|
UTSW |
6 |
98,993,502 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2338:Foxp1
|
UTSW |
6 |
98,980,254 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R3896:Foxp1
|
UTSW |
6 |
99,052,897 (GRCm39) |
missense |
probably benign |
0.33 |
|
R5006:Foxp1
|
UTSW |
6 |
99,139,819 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5143:Foxp1
|
UTSW |
6 |
98,922,493 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5428:Foxp1
|
UTSW |
6 |
98,993,592 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5765:Foxp1
|
UTSW |
6 |
98,992,423 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5816:Foxp1
|
UTSW |
6 |
99,052,926 (GRCm39) |
small deletion |
probably benign |
|
|
R6172:Foxp1
|
UTSW |
6 |
98,992,475 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6172:Foxp1
|
UTSW |
6 |
98,992,471 (GRCm39) |
nonsense |
probably null |
|
|
R6173:Foxp1
|
UTSW |
6 |
98,992,475 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6173:Foxp1
|
UTSW |
6 |
98,992,471 (GRCm39) |
nonsense |
probably null |
|
|
R6175:Foxp1
|
UTSW |
6 |
98,943,037 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6776:Foxp1
|
UTSW |
6 |
99,052,926 (GRCm39) |
small deletion |
probably benign |
|
|
R6782:Foxp1
|
UTSW |
6 |
98,907,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7229:Foxp1
|
UTSW |
6 |
98,912,373 (GRCm39) |
missense |
unknown |
|
|
R7559:Foxp1
|
UTSW |
6 |
98,922,521 (GRCm39) |
missense |
unknown |
|
|
R7715:Foxp1
|
UTSW |
6 |
98,922,621 (GRCm39) |
missense |
unknown |
|
|
R8099:Foxp1
|
UTSW |
6 |
98,922,510 (GRCm39) |
missense |
unknown |
|
|
R8317:Foxp1
|
UTSW |
6 |
99,052,866 (GRCm39) |
small deletion |
probably benign |
|
|
R8408:Foxp1
|
UTSW |
6 |
98,922,543 (GRCm39) |
missense |
unknown |
|
|
R8704:Foxp1
|
UTSW |
6 |
98,993,507 (GRCm39) |
missense |
unknown |
|
|
R8705:Foxp1
|
UTSW |
6 |
98,993,507 (GRCm39) |
missense |
unknown |
|
|
R9014:Foxp1
|
UTSW |
6 |
99,052,866 (GRCm39) |
small deletion |
probably benign |
|
|
R9147:Foxp1
|
UTSW |
6 |
99,052,866 (GRCm39) |
small deletion |
probably benign |
|
|
R9399:Foxp1
|
UTSW |
6 |
99,052,866 (GRCm39) |
small deletion |
probably benign |
|
|
R9604:Foxp1
|
UTSW |
6 |
99,052,926 (GRCm39) |
small deletion |
probably benign |
|
|
X0066:Foxp1
|
UTSW |
6 |
99,052,976 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Foxp1
|
UTSW |
6 |
98,955,122 (GRCm39) |
missense |
unknown |
|
|
| Predicted Primers |
PCR Primer
(F):5'- AACGTGAAAACCAGGTCTTTG -3'
(R):5'- GACACTCGGAAGAAGATCCTC -3'
Sequencing Primer
(F):5'- CCAGGTCTTTGGTCTGACAC -3'
(R):5'- ACATGTGGGGCTGAATGT -3'
|
| Posted On |
2020-01-23 |
Incidental Mutation