Incidental Mutation 'R8832:Myo1c'
| ID |
673933 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myo1c
|
| Ensembl Gene |
ENSMUSG00000017774 |
| Gene Name |
myosin IC |
| Synonyms |
myr2, mm1beta, C80397, myosin-Ibeta |
| MMRRC Submission |
068660-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.684)
|
| Stock # |
R8832 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
11 |
| Chromosomal Location |
75541330-75564736 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 75561072 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Isoleucine
at position 793
(V793I)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000070388
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000069057]
[ENSMUST00000102504]
[ENSMUST00000102505]
[ENSMUST00000108431]
|
| AlphaFold |
Q9WTI7 |
| PDB Structure |
Crystal Structure of Myosin-1c tail in complex with Calmodulin [X-RAY DIFFRACTION]
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000069057
AA Change: V793I
PolyPhen 2
Score 0.026 (Sensitivity: 0.95; Specificity: 0.81)
|
| SMART Domains |
Protein: ENSMUSP00000070388
Gene: ENSMUSG00000017774
AA Change: V793I
| Domain | Start | End | E-Value | Type |
|---|
|
MYSc
|
5 |
697 |
N/A |
SMART |
|
IQ
|
698 |
720 |
3.85e-3 |
SMART |
|
IQ
|
721 |
743 |
2.09e-4 |
SMART |
|
Blast:MYSc
|
751 |
780 |
5e-9 |
BLAST |
|
low complexity region
|
804 |
815 |
N/A |
INTRINSIC |
|
Pfam:Myosin_TH1
|
838 |
1024 |
1.9e-41 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000102504
AA Change: V793I
PolyPhen 2
Score 0.026 (Sensitivity: 0.95; Specificity: 0.81)
|
| SMART Domains |
Protein: ENSMUSP00000099562
Gene: ENSMUSG00000017774
AA Change: V793I
| Domain | Start | End | E-Value | Type |
|---|
|
MYSc
|
5 |
697 |
N/A |
SMART |
|
IQ
|
698 |
720 |
3.85e-3 |
SMART |
|
IQ
|
721 |
743 |
2.09e-4 |
SMART |
|
Blast:MYSc
|
751 |
780 |
5e-9 |
BLAST |
|
low complexity region
|
804 |
815 |
N/A |
INTRINSIC |
|
Pfam:Myosin_TH1
|
838 |
1024 |
1.9e-41 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000102505
AA Change: V828I
PolyPhen 2
Score 0.026 (Sensitivity: 0.95; Specificity: 0.81)
|
| SMART Domains |
Protein: ENSMUSP00000099563
Gene: ENSMUSG00000017774
AA Change: V828I
| Domain | Start | End | E-Value | Type |
|---|
|
MYSc
|
40 |
732 |
N/A |
SMART |
|
IQ
|
733 |
755 |
3.85e-3 |
SMART |
|
IQ
|
756 |
778 |
2.09e-4 |
SMART |
|
Blast:MYSc
|
786 |
815 |
6e-9 |
BLAST |
|
low complexity region
|
839 |
850 |
N/A |
INTRINSIC |
|
Pfam:Myosin_TH1
|
874 |
1052 |
2.9e-29 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000108431
AA Change: V809I
PolyPhen 2
Score 0.044 (Sensitivity: 0.94; Specificity: 0.83)
|
| SMART Domains |
Protein: ENSMUSP00000104069
Gene: ENSMUSG00000017774
AA Change: V809I
| Domain | Start | End | E-Value | Type |
|---|
|
MYSc
|
21 |
713 |
N/A |
SMART |
|
IQ
|
714 |
736 |
3.85e-3 |
SMART |
|
IQ
|
737 |
759 |
2.09e-4 |
SMART |
|
Blast:MYSc
|
767 |
796 |
5e-9 |
BLAST |
|
low complexity region
|
820 |
831 |
N/A |
INTRINSIC |
|
Pfam:Myosin_TH1
|
854 |
1040 |
3.3e-41 |
PFAM |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.5%
- 20x: 98.5%
|
| Validation Efficiency |
99% (81/82) |
| MGI Phenotype |
FUNCTION: This gene encodes a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The protein functions in intracellular vesicle transport to the plasma membrane. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a knock-in (Y61G) mutation that sensitizes to N6-modified ADP analogs display altered fast adaption in vestibular hair cells. Mice homozygous for a nuclear isoform-specifc knock-out allele exhibit minor changes in bone marrow density and red blood cells. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 83 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 9330159F19Rik |
A |
T |
10: 29,100,341 (GRCm39) |
E238V |
probably damaging |
Het |
| Adh6b |
T |
C |
3: 138,055,463 (GRCm39) |
V71A |
probably benign |
Het |
| Agmat |
G |
A |
4: 141,474,320 (GRCm39) |
R67H |
probably benign |
Het |
| AI182371 |
T |
C |
2: 34,985,909 (GRCm39) |
D49G |
unknown |
Het |
| Ak7 |
A |
G |
12: 105,708,598 (GRCm39) |
N351S |
possibly damaging |
Het |
| Aldh3b1 |
G |
T |
19: 3,964,025 (GRCm39) |
R426S |
probably damaging |
Het |
| Aldh4a1 |
A |
G |
4: 139,371,466 (GRCm39) |
D460G |
probably benign |
Het |
| Aox4 |
A |
T |
1: 58,294,649 (GRCm39) |
M953L |
probably benign |
Het |
| Arhgap32 |
C |
T |
9: 32,172,115 (GRCm39) |
P1632S |
possibly damaging |
Het |
| Armh1 |
A |
G |
4: 117,094,867 (GRCm39) |
F58L |
probably damaging |
Het |
| Baz1b |
C |
T |
5: 135,246,230 (GRCm39) |
R560W |
possibly damaging |
Het |
| Bbs10 |
C |
T |
10: 111,136,266 (GRCm39) |
Q460* |
probably null |
Het |
| BC034090 |
A |
C |
1: 155,102,034 (GRCm39) |
S77A |
probably damaging |
Het |
| Bltp2 |
A |
G |
11: 78,158,064 (GRCm39) |
K409E |
probably benign |
Het |
| Brca2 |
A |
G |
5: 150,465,611 (GRCm39) |
K1792E |
possibly damaging |
Het |
| Cadps2 |
A |
T |
6: 23,587,536 (GRCm39) |
L318Q |
possibly damaging |
Het |
| Catsperg2 |
A |
G |
7: 29,397,269 (GRCm39) |
V1078A |
probably benign |
Het |
| Ccno |
A |
G |
13: 113,126,239 (GRCm39) |
N236S |
probably benign |
Het |
| Chct1 |
A |
G |
11: 85,062,037 (GRCm39) |
D12G |
probably damaging |
Het |
| Cobll1 |
A |
T |
2: 64,929,602 (GRCm39) |
S575T |
probably damaging |
Het |
| Col6a4 |
A |
G |
9: 105,949,353 (GRCm39) |
Y761H |
probably benign |
Het |
| Cyp2j9 |
G |
T |
4: 96,474,121 (GRCm39) |
H106Q |
probably benign |
Het |
| Dennd2c |
T |
A |
3: 103,059,720 (GRCm39) |
|
probably null |
Het |
| Drd5 |
G |
A |
5: 38,477,078 (GRCm39) |
V24M |
probably benign |
Het |
| Dthd1 |
T |
C |
5: 62,971,608 (GRCm39) |
S144P |
probably benign |
Het |
| Fcna |
C |
A |
2: 25,516,145 (GRCm39) |
R124L |
possibly damaging |
Het |
| Fmnl2 |
A |
G |
2: 52,944,584 (GRCm39) |
S188G |
|
Het |
| Ggt1 |
A |
T |
10: 75,410,173 (GRCm39) |
H35L |
possibly damaging |
Het |
| Gphn |
A |
T |
12: 78,459,174 (GRCm39) |
|
silent |
Het |
| Hic1 |
G |
A |
11: 75,057,728 (GRCm39) |
A387V |
possibly damaging |
Het |
| Hycc2 |
A |
T |
1: 58,587,832 (GRCm39) |
I127N |
possibly damaging |
Het |
| Igf1r |
T |
A |
7: 67,875,769 (GRCm39) |
F1244I |
probably damaging |
Het |
| Kcnk7 |
T |
C |
19: 5,754,736 (GRCm39) |
V78A |
probably damaging |
Het |
| Kit |
A |
G |
5: 75,799,791 (GRCm39) |
N508D |
probably benign |
Het |
| Klk1b22 |
A |
T |
7: 43,764,277 (GRCm39) |
E68D |
probably benign |
Het |
| Klra4 |
C |
T |
6: 130,021,019 (GRCm39) |
D259N |
probably benign |
Het |
| Krtap2-4 |
A |
T |
11: 99,505,246 (GRCm39) |
C122S |
unknown |
Het |
| Map3k1 |
T |
G |
13: 111,889,015 (GRCm39) |
H1314P |
possibly damaging |
Het |
| Mast2 |
C |
T |
4: 116,168,875 (GRCm39) |
|
probably null |
Het |
| Mfsd2a |
A |
G |
4: 122,843,102 (GRCm39) |
V393A |
probably benign |
Het |
| Myh7b |
T |
A |
2: 155,475,182 (GRCm39) |
V1858E |
probably benign |
Het |
| Myt1l |
T |
A |
12: 29,970,351 (GRCm39) |
N1145K |
unknown |
Het |
| Nckap1l |
T |
A |
15: 103,387,242 (GRCm39) |
S706T |
probably benign |
Het |
| Nos2 |
A |
G |
11: 78,846,290 (GRCm39) |
|
probably null |
Het |
| Odf2l |
C |
T |
3: 144,833,820 (GRCm39) |
S160L |
probably benign |
Het |
| Or10ag54 |
T |
A |
2: 87,099,743 (GRCm39) |
M206K |
probably benign |
Het |
| Or2av9 |
T |
C |
11: 58,381,063 (GRCm39) |
I173V |
possibly damaging |
Het |
| Or4p18 |
A |
G |
2: 88,233,137 (GRCm39) |
I47T |
probably damaging |
Het |
| Or56b34 |
T |
C |
7: 104,937,435 (GRCm39) |
L45P |
possibly damaging |
Het |
| Or8g53 |
T |
C |
9: 39,683,886 (GRCm39) |
D70G |
probably damaging |
Het |
| Pclo |
T |
C |
5: 14,838,464 (GRCm39) |
W1424R |
|
Het |
| Pde8a |
A |
G |
7: 80,956,498 (GRCm39) |
N299S |
probably benign |
Het |
| Pi4kb |
C |
T |
3: 94,900,344 (GRCm39) |
T326M |
probably damaging |
Het |
| Pip4k2c |
A |
T |
10: 127,037,037 (GRCm39) |
H177Q |
probably damaging |
Het |
| Pld1 |
T |
A |
3: 28,177,846 (GRCm39) |
W686R |
|
Het |
| Ppp1r3b |
A |
T |
8: 35,851,419 (GRCm39) |
D86V |
probably damaging |
Het |
| Ppp1r3g |
C |
T |
13: 36,153,143 (GRCm39) |
R188* |
probably null |
Het |
| Pramel48 |
G |
T |
5: 95,630,939 (GRCm39) |
C272F |
possibly damaging |
Het |
| Ptbp1 |
A |
G |
10: 79,699,023 (GRCm39) |
E527G |
probably damaging |
Het |
| Rasef |
T |
C |
4: 73,698,558 (GRCm39) |
|
probably benign |
Het |
| Rce1 |
A |
T |
19: 4,675,532 (GRCm39) |
C34S |
unknown |
Het |
| Rnf144a |
T |
C |
12: 26,370,948 (GRCm39) |
|
probably benign |
Het |
| Rpl7 |
C |
T |
1: 16,173,485 (GRCm39) |
R88H |
possibly damaging |
Het |
| Rubcnl |
A |
T |
14: 75,269,359 (GRCm39) |
T6S |
|
Het |
| Samd9l |
A |
T |
6: 3,374,990 (GRCm39) |
V757D |
probably damaging |
Het |
| Sec22c |
A |
G |
9: 121,514,638 (GRCm39) |
V221A |
probably benign |
Het |
| Slc16a6 |
A |
G |
11: 109,345,932 (GRCm39) |
Y444H |
probably benign |
Het |
| Slc6a15 |
A |
T |
10: 103,225,179 (GRCm39) |
Y89F |
probably damaging |
Het |
| Smg1 |
A |
G |
7: 117,739,006 (GRCm39) |
V3466A |
probably benign |
Het |
| Sobp |
G |
A |
10: 43,036,824 (GRCm39) |
T38I |
probably damaging |
Het |
| Sppl2b |
TGTCACAGGT |
TGT |
10: 80,701,903 (GRCm39) |
|
probably null |
Het |
| Srsf5 |
T |
A |
12: 80,996,278 (GRCm39) |
F151I |
probably damaging |
Het |
| Taf2 |
A |
C |
15: 54,928,001 (GRCm39) |
L134R |
possibly damaging |
Het |
| Tbc1d1 |
A |
G |
5: 64,442,020 (GRCm39) |
|
probably benign |
Het |
| Thap1 |
C |
T |
8: 26,648,261 (GRCm39) |
|
probably benign |
Het |
| Tmc5 |
A |
T |
7: 118,222,332 (GRCm39) |
M11L |
probably benign |
Het |
| Tnfaip8 |
ACACACTCTCTCTCTC |
AC |
18: 50,179,908 (GRCm39) |
|
probably benign |
Het |
| Tomm7 |
T |
C |
5: 24,049,047 (GRCm39) |
K9E |
possibly damaging |
Het |
| Trem3 |
T |
C |
17: 48,556,865 (GRCm39) |
V112A |
probably benign |
Het |
| Vmn1r178 |
G |
A |
7: 23,593,264 (GRCm39) |
C104Y |
probably damaging |
Het |
| Zdhhc20 |
A |
T |
14: 58,080,721 (GRCm39) |
S263T |
possibly damaging |
Het |
| Zdhhc20 |
A |
G |
14: 58,103,089 (GRCm39) |
S87P |
probably benign |
Het |
| Zfp423 |
C |
A |
8: 88,507,827 (GRCm39) |
C839F |
probably damaging |
Het |
|
| Other mutations in Myo1c |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01346:Myo1c
|
APN |
11 |
75,563,076 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02054:Myo1c
|
APN |
11 |
75,551,962 (GRCm39) |
missense |
probably benign |
0.30 |
|
IGL02115:Myo1c
|
APN |
11 |
75,552,417 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02375:Myo1c
|
APN |
11 |
75,552,400 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02878:Myo1c
|
APN |
11 |
75,559,859 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL03008:Myo1c
|
APN |
11 |
75,549,240 (GRCm39) |
missense |
probably benign |
0.13 |
|
Sweeper
|
UTSW |
11 |
75,560,856 (GRCm39) |
nonsense |
probably null |
|
|
R0070:Myo1c
|
UTSW |
11 |
75,551,076 (GRCm39) |
missense |
probably benign |
0.39 |
|
R0070:Myo1c
|
UTSW |
11 |
75,551,076 (GRCm39) |
missense |
probably benign |
0.39 |
|
R0138:Myo1c
|
UTSW |
11 |
75,551,827 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0200:Myo1c
|
UTSW |
11 |
75,563,008 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0227:Myo1c
|
UTSW |
11 |
75,549,520 (GRCm39) |
missense |
probably benign |
0.34 |
|
R0257:Myo1c
|
UTSW |
11 |
75,556,342 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0513:Myo1c
|
UTSW |
11 |
75,556,657 (GRCm39) |
splice site |
probably null |
|
|
R0587:Myo1c
|
UTSW |
11 |
75,548,616 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0667:Myo1c
|
UTSW |
11 |
75,559,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1469:Myo1c
|
UTSW |
11 |
75,560,787 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1469:Myo1c
|
UTSW |
11 |
75,560,787 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1793:Myo1c
|
UTSW |
11 |
75,548,415 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1922:Myo1c
|
UTSW |
11 |
75,559,055 (GRCm39) |
missense |
probably benign |
|
|
R2000:Myo1c
|
UTSW |
11 |
75,561,405 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3983:Myo1c
|
UTSW |
11 |
75,552,325 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4583:Myo1c
|
UTSW |
11 |
75,562,688 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R4599:Myo1c
|
UTSW |
11 |
75,559,019 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4671:Myo1c
|
UTSW |
11 |
75,560,856 (GRCm39) |
nonsense |
probably null |
|
|
R4682:Myo1c
|
UTSW |
11 |
75,560,856 (GRCm39) |
nonsense |
probably null |
|
|
R4708:Myo1c
|
UTSW |
11 |
75,560,856 (GRCm39) |
nonsense |
probably null |
|
|
R4709:Myo1c
|
UTSW |
11 |
75,560,856 (GRCm39) |
nonsense |
probably null |
|
|
R4742:Myo1c
|
UTSW |
11 |
75,560,856 (GRCm39) |
nonsense |
probably null |
|
|
R4770:Myo1c
|
UTSW |
11 |
75,551,139 (GRCm39) |
nonsense |
probably null |
|
|
R4888:Myo1c
|
UTSW |
11 |
75,560,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4915:Myo1c
|
UTSW |
11 |
75,547,135 (GRCm39) |
start codon destroyed |
probably null |
|
|
R4934:Myo1c
|
UTSW |
11 |
75,562,676 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4971:Myo1c
|
UTSW |
11 |
75,562,414 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5319:Myo1c
|
UTSW |
11 |
75,552,852 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5589:Myo1c
|
UTSW |
11 |
75,548,414 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R5624:Myo1c
|
UTSW |
11 |
75,553,461 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5756:Myo1c
|
UTSW |
11 |
75,549,240 (GRCm39) |
missense |
probably benign |
0.42 |
|
R5959:Myo1c
|
UTSW |
11 |
75,548,345 (GRCm39) |
missense |
probably benign |
0.37 |
|
R6160:Myo1c
|
UTSW |
11 |
75,541,568 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6559:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6568:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6569:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6574:Myo1c
|
UTSW |
11 |
75,547,124 (GRCm39) |
start gained |
probably benign |
|
|
R6579:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6580:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6583:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6640:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6642:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6643:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6679:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6680:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6687:Myo1c
|
UTSW |
11 |
75,563,027 (GRCm39) |
missense |
probably benign |
|
|
R6695:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6696:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6700:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6712:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6713:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6715:Myo1c
|
UTSW |
11 |
75,562,461 (GRCm39) |
missense |
probably benign |
0.42 |
|
R7081:Myo1c
|
UTSW |
11 |
75,551,789 (GRCm39) |
missense |
probably benign |
|
|
R7265:Myo1c
|
UTSW |
11 |
75,560,616 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7397:Myo1c
|
UTSW |
11 |
75,562,068 (GRCm39) |
missense |
probably benign |
0.17 |
|
R7586:Myo1c
|
UTSW |
11 |
75,548,345 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R7714:Myo1c
|
UTSW |
11 |
75,549,519 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8260:Myo1c
|
UTSW |
11 |
75,546,942 (GRCm39) |
unclassified |
probably benign |
|
|
R8341:Myo1c
|
UTSW |
11 |
75,562,253 (GRCm39) |
missense |
probably benign |
0.42 |
|
R8466:Myo1c
|
UTSW |
11 |
75,549,213 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8771:Myo1c
|
UTSW |
11 |
75,556,709 (GRCm39) |
missense |
probably benign |
|
|
R8829:Myo1c
|
UTSW |
11 |
75,561,072 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9243:Myo1c
|
UTSW |
11 |
75,541,437 (GRCm39) |
unclassified |
probably benign |
|
|
R9489:Myo1c
|
UTSW |
11 |
75,559,899 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9605:Myo1c
|
UTSW |
11 |
75,559,899 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9744:Myo1c
|
UTSW |
11 |
75,562,797 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9782:Myo1c
|
UTSW |
11 |
75,549,273 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CCAGTGTGTGGGAACTACAG -3'
(R):5'- GAGTGTTTTCTCTCCAGCAAAC -3'
Sequencing Primer
(F):5'- GATCAAAGTGAGTATGGGGATCTTC -3'
(R):5'- TCTCCAGCAAACTCATTTCCATAAC -3'
|
| Posted On |
2021-07-15 |
Incidental Mutation