Incidental Mutation 'R9022:Hivep3'
| ID |
686265 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Hivep3
|
| Ensembl Gene |
ENSMUSG00000028634 |
| Gene Name |
human immunodeficiency virus type I enhancer binding protein 3 |
| Synonyms |
Krc, E030045D18Rik, Schnurri-3, Shn3, 2900056N03Rik |
| MMRRC Submission |
068852-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R9022 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
4 |
| Chromosomal Location |
119590982-119992608 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 119955304 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Proline
at position 1207
(S1207P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000101914
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000106307]
[ENSMUST00000166542]
[ENSMUST00000226560]
|
| AlphaFold |
A2A884 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000106307
AA Change: S1207P
PolyPhen 2
Score 0.093 (Sensitivity: 0.93; Specificity: 0.85)
|
| SMART Domains |
Protein: ENSMUSP00000101914
Gene: ENSMUSG00000028634
AA Change: S1207P
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
185 |
207 |
1.67e-2 |
SMART |
|
ZnF_C2H2
|
213 |
235 |
8.34e-3 |
SMART |
|
low complexity region
|
257 |
285 |
N/A |
INTRINSIC |
|
low complexity region
|
292 |
323 |
N/A |
INTRINSIC |
|
low complexity region
|
425 |
438 |
N/A |
INTRINSIC |
|
low complexity region
|
513 |
527 |
N/A |
INTRINSIC |
|
low complexity region
|
589 |
612 |
N/A |
INTRINSIC |
|
low complexity region
|
622 |
633 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
636 |
656 |
2.06e1 |
SMART |
|
low complexity region
|
736 |
749 |
N/A |
INTRINSIC |
|
low complexity region
|
806 |
817 |
N/A |
INTRINSIC |
|
low complexity region
|
844 |
865 |
N/A |
INTRINSIC |
|
low complexity region
|
878 |
894 |
N/A |
INTRINSIC |
|
low complexity region
|
896 |
931 |
N/A |
INTRINSIC |
|
low complexity region
|
1010 |
1020 |
N/A |
INTRINSIC |
|
low complexity region
|
1050 |
1061 |
N/A |
INTRINSIC |
|
low complexity region
|
1110 |
1136 |
N/A |
INTRINSIC |
|
low complexity region
|
1143 |
1167 |
N/A |
INTRINSIC |
|
low complexity region
|
1170 |
1183 |
N/A |
INTRINSIC |
|
low complexity region
|
1259 |
1284 |
N/A |
INTRINSIC |
|
low complexity region
|
1376 |
1390 |
N/A |
INTRINSIC |
|
low complexity region
|
1529 |
1547 |
N/A |
INTRINSIC |
|
low complexity region
|
1673 |
1684 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1720 |
1742 |
1.82e-3 |
SMART |
|
ZnF_C2H2
|
1748 |
1772 |
1.69e-3 |
SMART |
|
low complexity region
|
1778 |
1791 |
N/A |
INTRINSIC |
|
low complexity region
|
1814 |
1843 |
N/A |
INTRINSIC |
|
low complexity region
|
2203 |
2216 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000166542
AA Change: S1207P
PolyPhen 2
Score 0.093 (Sensitivity: 0.93; Specificity: 0.85)
|
| SMART Domains |
Protein: ENSMUSP00000130249
Gene: ENSMUSG00000028634
AA Change: S1207P
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
185 |
207 |
1.67e-2 |
SMART |
|
ZnF_C2H2
|
213 |
235 |
8.34e-3 |
SMART |
|
low complexity region
|
257 |
285 |
N/A |
INTRINSIC |
|
low complexity region
|
292 |
323 |
N/A |
INTRINSIC |
|
low complexity region
|
425 |
438 |
N/A |
INTRINSIC |
|
low complexity region
|
513 |
527 |
N/A |
INTRINSIC |
|
low complexity region
|
589 |
612 |
N/A |
INTRINSIC |
|
low complexity region
|
622 |
633 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
636 |
656 |
2.06e1 |
SMART |
|
low complexity region
|
736 |
749 |
N/A |
INTRINSIC |
|
low complexity region
|
806 |
817 |
N/A |
INTRINSIC |
|
low complexity region
|
844 |
865 |
N/A |
INTRINSIC |
|
low complexity region
|
878 |
894 |
N/A |
INTRINSIC |
|
low complexity region
|
896 |
931 |
N/A |
INTRINSIC |
|
low complexity region
|
1010 |
1020 |
N/A |
INTRINSIC |
|
low complexity region
|
1050 |
1061 |
N/A |
INTRINSIC |
|
low complexity region
|
1110 |
1136 |
N/A |
INTRINSIC |
|
low complexity region
|
1143 |
1167 |
N/A |
INTRINSIC |
|
low complexity region
|
1170 |
1183 |
N/A |
INTRINSIC |
|
low complexity region
|
1259 |
1284 |
N/A |
INTRINSIC |
|
low complexity region
|
1376 |
1390 |
N/A |
INTRINSIC |
|
low complexity region
|
1529 |
1547 |
N/A |
INTRINSIC |
|
low complexity region
|
1673 |
1684 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1720 |
1742 |
1.82e-3 |
SMART |
|
ZnF_C2H2
|
1748 |
1772 |
1.69e-3 |
SMART |
|
low complexity region
|
1778 |
1791 |
N/A |
INTRINSIC |
|
low complexity region
|
1814 |
1843 |
N/A |
INTRINSIC |
|
low complexity region
|
2203 |
2216 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000226560
|
| Meta Mutation Damage Score |
0.0716 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.5%
|
| Validation Efficiency |
100% (84/84) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the human immunodeficiency virus type 1 enhancer-binding protein family. Members of this protein family contain multiple zinc finger and acid-rich (ZAS) domains and serine-threonine rich regions. This protein acts as a transcription factor and is able to regulate nuclear factor kappaB-mediated transcription by binding the kappaB motif in target genes. This protein also binds the recombination signal sequence that flanks the V, D, and J regions of immunoglobulin and T-cell receptors. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Sep 2011]
PHENOTYPE: Homozygous mutation of this gene results in diminished IL-2 production by stimulated CD4 cells. Mice homozygous for a knock-out allele exhibit increased bone volume. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 84 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Actl6a |
G |
T |
3: 32,769,649 (GRCm39) |
A155S |
probably benign |
Het |
| Adar |
A |
G |
3: 89,643,045 (GRCm39) |
T309A |
probably benign |
Het |
| Adgrv1 |
A |
T |
13: 81,303,312 (GRCm39) |
W6125R |
probably damaging |
Het |
| Adprhl1 |
A |
G |
8: 13,274,352 (GRCm39) |
L802P |
probably benign |
Het |
| Ahcy |
A |
G |
2: 154,910,779 (GRCm39) |
L63P |
probably damaging |
Het |
| Ang5 |
G |
A |
14: 44,200,352 (GRCm39) |
D139N |
probably damaging |
Het |
| Ankrd31 |
A |
G |
13: 96,962,655 (GRCm39) |
D482G |
probably benign |
Het |
| Arhgef7 |
A |
G |
8: 11,850,469 (GRCm39) |
N257D |
probably benign |
Het |
| Art3 |
C |
A |
5: 92,540,393 (GRCm39) |
S45R |
probably benign |
Het |
| Atxn1 |
T |
C |
13: 45,720,891 (GRCm39) |
R335G |
probably damaging |
Het |
| Bag6 |
T |
A |
17: 35,363,641 (GRCm39) |
L775H |
probably damaging |
Het |
| BC004004 |
T |
G |
17: 29,501,130 (GRCm39) |
H26Q |
possibly damaging |
Het |
| Camsap3 |
T |
C |
8: 3,656,575 (GRCm39) |
L986S |
probably benign |
Het |
| Cbx5 |
T |
C |
15: 103,121,586 (GRCm39) |
E17G |
probably damaging |
Het |
| Cc2d1b |
T |
C |
4: 108,484,617 (GRCm39) |
|
probably null |
Het |
| Ccdc59 |
T |
C |
10: 105,683,007 (GRCm39) |
Y231H |
probably damaging |
Het |
| Cemip2 |
T |
C |
19: 21,789,986 (GRCm39) |
|
probably null |
Het |
| Csnk1g1 |
T |
C |
9: 65,917,854 (GRCm39) |
|
probably null |
Het |
| Cybrd1 |
A |
G |
2: 70,967,904 (GRCm39) |
I158M |
possibly damaging |
Het |
| Disp2 |
T |
A |
2: 118,621,179 (GRCm39) |
I637N |
probably benign |
Het |
| Dll4 |
TC |
T |
2: 119,163,054 (GRCm39) |
|
probably null |
Het |
| Dnah7a |
T |
C |
1: 53,512,116 (GRCm39) |
|
probably null |
Het |
| Duox2 |
C |
A |
2: 122,110,919 (GRCm39) |
*1518L |
probably null |
Het |
| Dym |
A |
G |
18: 75,258,507 (GRCm39) |
I422V |
probably benign |
Het |
| Entpd8 |
A |
C |
2: 24,975,144 (GRCm39) |
I492L |
probably benign |
Het |
| Fabp12 |
A |
G |
3: 10,317,333 (GRCm39) |
S13P |
probably damaging |
Het |
| Fam124b |
A |
G |
1: 80,190,705 (GRCm39) |
I226T |
probably damaging |
Het |
| Fer1l6 |
T |
C |
15: 58,455,329 (GRCm39) |
L763P |
probably damaging |
Het |
| Git2 |
A |
G |
5: 114,907,676 (GRCm39) |
|
probably null |
Het |
| Gltpd2 |
A |
T |
11: 70,410,153 (GRCm39) |
Y37F |
probably benign |
Het |
| Gm44511 |
T |
G |
6: 128,797,271 (GRCm39) |
Q72H |
possibly damaging |
Het |
| Grid2ip |
A |
T |
5: 143,366,204 (GRCm39) |
T565S |
probably benign |
Het |
| Grk6 |
T |
C |
13: 55,606,877 (GRCm39) |
S532P |
possibly damaging |
Het |
| Haspin |
A |
T |
11: 73,026,831 (GRCm39) |
F753I |
probably damaging |
Het |
| Herpud1 |
T |
A |
8: 95,116,197 (GRCm39) |
S92T |
possibly damaging |
Het |
| Heyl |
C |
T |
4: 123,139,768 (GRCm39) |
A109V |
probably damaging |
Het |
| Hk1 |
A |
G |
10: 62,105,768 (GRCm39) |
S893P |
probably damaging |
Het |
| Itih1 |
C |
A |
14: 30,652,327 (GRCm39) |
V789L |
probably benign |
Het |
| Kif12 |
T |
C |
4: 63,090,121 (GRCm39) |
D10G |
possibly damaging |
Het |
| Kif16b |
C |
T |
2: 142,554,537 (GRCm39) |
E754K |
possibly damaging |
Het |
| Kif20a |
A |
G |
18: 34,760,898 (GRCm39) |
Q191R |
probably benign |
Het |
| Lap3 |
A |
G |
5: 45,652,548 (GRCm39) |
D48G |
probably benign |
Het |
| Matn3 |
T |
A |
12: 9,002,355 (GRCm39) |
V189E |
probably damaging |
Het |
| Mbp |
G |
A |
18: 82,597,067 (GRCm39) |
E143K |
possibly damaging |
Het |
| Mrgprd |
A |
G |
7: 144,875,555 (GRCm39) |
H142R |
probably benign |
Het |
| Nbea |
A |
T |
3: 55,551,110 (GRCm39) |
C2685S |
possibly damaging |
Het |
| Nhsl1 |
A |
C |
10: 18,403,409 (GRCm39) |
I1381L |
possibly damaging |
Het |
| Npc1 |
A |
G |
18: 12,346,422 (GRCm39) |
M258T |
probably benign |
Het |
| Or2w3 |
T |
C |
11: 58,556,550 (GRCm39) |
L55P |
probably damaging |
Het |
| Or7e178 |
T |
A |
9: 20,225,268 (GRCm39) |
N316I |
probably damaging |
Het |
| Osbpl10 |
C |
T |
9: 114,807,939 (GRCm39) |
A65V |
unknown |
Het |
| Pdia4 |
C |
G |
6: 47,785,149 (GRCm39) |
A73P |
probably benign |
Het |
| Plxnb2 |
T |
C |
15: 89,048,471 (GRCm39) |
Y646C |
possibly damaging |
Het |
| Pmm1 |
C |
T |
15: 81,839,896 (GRCm39) |
R143H |
probably damaging |
Het |
| Pold2 |
T |
C |
11: 5,824,121 (GRCm39) |
D228G |
probably benign |
Het |
| Popdc2 |
T |
G |
16: 38,194,508 (GRCm39) |
C310G |
probably benign |
Het |
| Prdm10 |
A |
G |
9: 31,268,424 (GRCm39) |
Y791C |
probably benign |
Het |
| Psg19 |
C |
T |
7: 18,530,762 (GRCm39) |
V131I |
probably benign |
Het |
| Psg19 |
T |
A |
7: 18,531,044 (GRCm39) |
T37S |
probably benign |
Het |
| Psme1 |
A |
G |
14: 55,817,271 (GRCm39) |
E39G |
probably damaging |
Het |
| Rabep2 |
A |
G |
7: 126,043,719 (GRCm39) |
E472G |
probably damaging |
Het |
| Rap1gap |
T |
C |
4: 137,445,309 (GRCm39) |
F297S |
probably damaging |
Het |
| Reln |
A |
G |
5: 22,181,613 (GRCm39) |
S1757P |
possibly damaging |
Het |
| Rybp |
G |
T |
6: 100,210,074 (GRCm39) |
D95E |
possibly damaging |
Het |
| Slc12a8 |
T |
A |
16: 33,466,934 (GRCm39) |
D480E |
probably benign |
Het |
| Slc25a1 |
A |
G |
16: 17,745,294 (GRCm39) |
V80A |
probably benign |
Het |
| Slc25a24 |
A |
T |
3: 109,070,757 (GRCm39) |
D372V |
probably benign |
Het |
| Slc49a4 |
T |
C |
16: 35,570,912 (GRCm39) |
T131A |
probably benign |
Het |
| Stab1 |
T |
C |
14: 30,882,226 (GRCm39) |
T490A |
probably benign |
Het |
| Stat5b |
A |
T |
11: 100,681,634 (GRCm39) |
I540N |
probably benign |
Het |
| Tasor2 |
A |
G |
13: 3,626,659 (GRCm39) |
V1097A |
probably benign |
Het |
| Thy1 |
T |
A |
9: 43,957,947 (GRCm39) |
L25Q |
probably damaging |
Het |
| Trim30a |
A |
G |
7: 104,084,956 (GRCm39) |
S85P |
probably benign |
Het |
| Use1 |
G |
A |
8: 71,819,942 (GRCm39) |
V36I |
probably benign |
Het |
| Vmn1r228 |
T |
A |
17: 20,996,778 (GRCm39) |
I247F |
probably damaging |
Het |
| Vmn2r13 |
T |
A |
5: 109,304,242 (GRCm39) |
T730S |
possibly damaging |
Het |
| Vmn2r9 |
T |
C |
5: 108,992,923 (GRCm39) |
D529G |
possibly damaging |
Het |
| Washc5 |
A |
G |
15: 59,217,233 (GRCm39) |
I778T |
possibly damaging |
Het |
| Washc5 |
A |
T |
15: 59,233,069 (GRCm39) |
M294K |
probably damaging |
Het |
| Wnt8a |
A |
T |
18: 34,680,298 (GRCm39) |
D221V |
probably damaging |
Het |
| Zfp616 |
A |
G |
11: 73,976,539 (GRCm39) |
K936R |
probably damaging |
Het |
| Zfp618 |
G |
A |
4: 63,012,687 (GRCm39) |
C133Y |
probably damaging |
Het |
| Zfp82 |
A |
G |
7: 29,761,714 (GRCm39) |
S56P |
probably damaging |
Het |
| Zkscan16 |
T |
A |
4: 58,957,021 (GRCm39) |
D434E |
probably benign |
Het |
|
| Other mutations in Hivep3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00953:Hivep3
|
APN |
4 |
119,955,571 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01017:Hivep3
|
APN |
4 |
119,956,443 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01837:Hivep3
|
APN |
4 |
119,951,759 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
IGL01878:Hivep3
|
APN |
4 |
119,952,424 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
IGL02134:Hivep3
|
APN |
4 |
119,990,771 (GRCm39) |
splice site |
probably benign |
|
|
IGL02183:Hivep3
|
APN |
4 |
119,989,221 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02350:Hivep3
|
APN |
4 |
119,980,222 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02451:Hivep3
|
APN |
4 |
119,991,162 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02567:Hivep3
|
APN |
4 |
119,991,153 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02617:Hivep3
|
APN |
4 |
119,952,641 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02725:Hivep3
|
APN |
4 |
119,953,019 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
IGL02828:Hivep3
|
APN |
4 |
119,954,929 (GRCm39) |
nonsense |
probably null |
|
|
IGL02954:Hivep3
|
APN |
4 |
119,990,838 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02966:Hivep3
|
APN |
4 |
119,989,383 (GRCm39) |
missense |
probably benign |
0.04 |
|
Branchial
|
UTSW |
4 |
119,953,772 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
Deceit
|
UTSW |
4 |
119,955,108 (GRCm39) |
frame shift |
probably null |
|
|
Mandible
|
UTSW |
4 |
119,954,318 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Sclerotic
|
UTSW |
4 |
119,952,296 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
Stealth
|
UTSW |
4 |
119,980,073 (GRCm39) |
nonsense |
probably null |
|
|
Yellowjacket
|
UTSW |
4 |
119,989,554 (GRCm39) |
missense |
probably benign |
0.01 |
|
PIT4260001:Hivep3
|
UTSW |
4 |
119,956,379 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0321:Hivep3
|
UTSW |
4 |
119,952,788 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R0336:Hivep3
|
UTSW |
4 |
119,961,044 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0558:Hivep3
|
UTSW |
4 |
119,953,763 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0562:Hivep3
|
UTSW |
4 |
119,953,751 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0637:Hivep3
|
UTSW |
4 |
119,989,738 (GRCm39) |
nonsense |
probably null |
|
|
R0645:Hivep3
|
UTSW |
4 |
119,954,531 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1186:Hivep3
|
UTSW |
4 |
119,671,920 (GRCm39) |
start gained |
probably benign |
|
|
R1254:Hivep3
|
UTSW |
4 |
119,956,490 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1428:Hivep3
|
UTSW |
4 |
119,953,772 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1623:Hivep3
|
UTSW |
4 |
119,952,901 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R1739:Hivep3
|
UTSW |
4 |
119,952,371 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1766:Hivep3
|
UTSW |
4 |
119,953,868 (GRCm39) |
missense |
probably benign |
|
|
R1769:Hivep3
|
UTSW |
4 |
119,954,768 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R1773:Hivep3
|
UTSW |
4 |
119,956,034 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1968:Hivep3
|
UTSW |
4 |
119,953,435 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R2220:Hivep3
|
UTSW |
4 |
119,591,235 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2428:Hivep3
|
UTSW |
4 |
119,955,705 (GRCm39) |
nonsense |
probably null |
|
|
R3789:Hivep3
|
UTSW |
4 |
119,955,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3917:Hivep3
|
UTSW |
4 |
119,956,624 (GRCm39) |
missense |
probably benign |
0.27 |
|
R4366:Hivep3
|
UTSW |
4 |
119,953,286 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R4436:Hivep3
|
UTSW |
4 |
119,953,120 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4504:Hivep3
|
UTSW |
4 |
119,590,990 (GRCm39) |
unclassified |
probably benign |
|
|
R4705:Hivep3
|
UTSW |
4 |
119,729,247 (GRCm39) |
intron |
probably benign |
|
|
R4713:Hivep3
|
UTSW |
4 |
119,989,000 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4756:Hivep3
|
UTSW |
4 |
119,955,020 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4887:Hivep3
|
UTSW |
4 |
119,980,131 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4888:Hivep3
|
UTSW |
4 |
119,980,131 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5008:Hivep3
|
UTSW |
4 |
119,956,114 (GRCm39) |
missense |
probably benign |
0.22 |
|
R5204:Hivep3
|
UTSW |
4 |
119,961,053 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5594:Hivep3
|
UTSW |
4 |
119,980,245 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5697:Hivep3
|
UTSW |
4 |
119,954,152 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R5715:Hivep3
|
UTSW |
4 |
119,953,570 (GRCm39) |
missense |
probably benign |
|
|
R5740:Hivep3
|
UTSW |
4 |
119,953,220 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R5760:Hivep3
|
UTSW |
4 |
119,952,208 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R5923:Hivep3
|
UTSW |
4 |
119,953,490 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5927:Hivep3
|
UTSW |
4 |
119,954,305 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R6042:Hivep3
|
UTSW |
4 |
119,955,061 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R6074:Hivep3
|
UTSW |
4 |
119,954,891 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R6150:Hivep3
|
UTSW |
4 |
119,591,274 (GRCm39) |
nonsense |
probably null |
|
|
R6211:Hivep3
|
UTSW |
4 |
119,955,602 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6251:Hivep3
|
UTSW |
4 |
119,952,137 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6451:Hivep3
|
UTSW |
4 |
119,956,105 (GRCm39) |
missense |
probably benign |
0.22 |
|
R6531:Hivep3
|
UTSW |
4 |
119,980,073 (GRCm39) |
nonsense |
probably null |
|
|
R6651:Hivep3
|
UTSW |
4 |
119,980,146 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6701:Hivep3
|
UTSW |
4 |
119,951,737 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6721:Hivep3
|
UTSW |
4 |
119,952,296 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R6796:Hivep3
|
UTSW |
4 |
119,953,558 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R6864:Hivep3
|
UTSW |
4 |
119,952,085 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R6902:Hivep3
|
UTSW |
4 |
119,953,192 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R7111:Hivep3
|
UTSW |
4 |
119,952,431 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R7113:Hivep3
|
UTSW |
4 |
119,955,566 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7140:Hivep3
|
UTSW |
4 |
119,954,318 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7189:Hivep3
|
UTSW |
4 |
119,989,416 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7218:Hivep3
|
UTSW |
4 |
119,952,649 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7366:Hivep3
|
UTSW |
4 |
119,955,108 (GRCm39) |
frame shift |
probably null |
|
|
R7368:Hivep3
|
UTSW |
4 |
119,955,108 (GRCm39) |
frame shift |
probably null |
|
|
R7491:Hivep3
|
UTSW |
4 |
119,956,027 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7496:Hivep3
|
UTSW |
4 |
119,989,599 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7514:Hivep3
|
UTSW |
4 |
119,954,052 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R7604:Hivep3
|
UTSW |
4 |
119,955,108 (GRCm39) |
frame shift |
probably null |
|
|
R7605:Hivep3
|
UTSW |
4 |
119,955,108 (GRCm39) |
frame shift |
probably null |
|
|
R7607:Hivep3
|
UTSW |
4 |
119,955,108 (GRCm39) |
frame shift |
probably null |
|
|
R7610:Hivep3
|
UTSW |
4 |
119,955,108 (GRCm39) |
frame shift |
probably null |
|
|
R7611:Hivep3
|
UTSW |
4 |
119,955,108 (GRCm39) |
frame shift |
probably null |
|
|
R7613:Hivep3
|
UTSW |
4 |
119,955,108 (GRCm39) |
frame shift |
probably null |
|
|
R7626:Hivep3
|
UTSW |
4 |
119,955,108 (GRCm39) |
frame shift |
probably null |
|
|
R7707:Hivep3
|
UTSW |
4 |
119,591,156 (GRCm39) |
missense |
|
|
|
R7736:Hivep3
|
UTSW |
4 |
119,952,740 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7915:Hivep3
|
UTSW |
4 |
119,954,962 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R7943:Hivep3
|
UTSW |
4 |
119,989,554 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7972:Hivep3
|
UTSW |
4 |
119,954,711 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R8093:Hivep3
|
UTSW |
4 |
119,952,632 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R8111:Hivep3
|
UTSW |
4 |
119,955,583 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8215:Hivep3
|
UTSW |
4 |
119,980,098 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8364:Hivep3
|
UTSW |
4 |
119,956,639 (GRCm39) |
missense |
probably benign |
0.10 |
|
R8467:Hivep3
|
UTSW |
4 |
119,952,238 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8768:Hivep3
|
UTSW |
4 |
119,989,521 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8890:Hivep3
|
UTSW |
4 |
119,953,657 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8902:Hivep3
|
UTSW |
4 |
119,953,937 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9336:Hivep3
|
UTSW |
4 |
119,952,400 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R9606:Hivep3
|
UTSW |
4 |
119,989,786 (GRCm39) |
missense |
probably damaging |
0.98 |
|
RF019:Hivep3
|
UTSW |
4 |
119,955,467 (GRCm39) |
missense |
probably benign |
0.12 |
|
X0062:Hivep3
|
UTSW |
4 |
119,955,895 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0067:Hivep3
|
UTSW |
4 |
119,988,984 (GRCm39) |
missense |
probably damaging |
0.96 |
|
Z1176:Hivep3
|
UTSW |
4 |
119,990,979 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Hivep3
|
UTSW |
4 |
119,988,975 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Hivep3
|
UTSW |
4 |
119,953,143 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
| Predicted Primers |
PCR Primer
(F):5'- GTTCTTCCCCACACAAGCAATG -3'
(R):5'- TGACACCATGGCATCTGGAC -3'
Sequencing Primer
(F):5'- CACAAGCAATGGCCGGC -3'
(R):5'- CATGGCATCTGGACAGGCAG -3'
|
| Posted On |
2021-10-11 |
Incidental Mutation