Incidental Mutation 'R9209:Nlgn1'
| ID |
698686 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Nlgn1
|
| Ensembl Gene |
ENSMUSG00000063887 |
| Gene Name |
neuroligin 1 |
| Synonyms |
NL1, Nlg1, 6330415N05Rik |
| MMRRC Submission |
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R9209 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
3 |
| Chromosomal Location |
25480379-26386609 bp(-) (GRCm39) |
| Type of Mutation |
critical splice donor site (2 bp from exon) |
| DNA Base Change (assembly) |
A to G
at 25966804 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000142200
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000075054]
[ENSMUST00000108308]
[ENSMUST00000191835]
[ENSMUST00000193603]
[ENSMUST00000193603]
[ENSMUST00000193603]
|
| AlphaFold |
Q99K10 |
| PDB Structure |
Crystal structure of a synaptic adhesion complex [X-RAY DIFFRACTION]
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000075054
|
| SMART Domains |
Protein: ENSMUSP00000074565
Gene: ENSMUSG00000063887
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:COesterase
|
29 |
626 |
4.8e-199 |
PFAM |
|
Pfam:Abhydrolase_3
|
196 |
302 |
2.2e-8 |
PFAM |
|
transmembrane domain
|
697 |
719 |
N/A |
INTRINSIC |
|
low complexity region
|
720 |
731 |
N/A |
INTRINSIC |
|
low complexity region
|
796 |
809 |
N/A |
INTRINSIC |
|
low complexity region
|
816 |
827 |
N/A |
INTRINSIC |
|
low complexity region
|
829 |
839 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000108308
|
| SMART Domains |
Protein: ENSMUSP00000103944
Gene: ENSMUSG00000063887
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:COesterase
|
29 |
597 |
2.5e-190 |
PFAM |
|
Pfam:Abhydrolase_3
|
176 |
306 |
4.3e-8 |
PFAM |
|
transmembrane domain
|
668 |
690 |
N/A |
INTRINSIC |
|
low complexity region
|
691 |
702 |
N/A |
INTRINSIC |
|
low complexity region
|
767 |
780 |
N/A |
INTRINSIC |
|
low complexity region
|
787 |
798 |
N/A |
INTRINSIC |
|
low complexity region
|
800 |
810 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000191835
|
| SMART Domains |
Protein: ENSMUSP00000142086
Gene: ENSMUSG00000063887
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:COesterase
|
29 |
597 |
2.5e-190 |
PFAM |
|
Pfam:Abhydrolase_3
|
176 |
306 |
4.3e-8 |
PFAM |
|
transmembrane domain
|
668 |
690 |
N/A |
INTRINSIC |
|
low complexity region
|
691 |
702 |
N/A |
INTRINSIC |
|
low complexity region
|
767 |
780 |
N/A |
INTRINSIC |
|
low complexity region
|
787 |
798 |
N/A |
INTRINSIC |
|
low complexity region
|
800 |
810 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000193603
|
| SMART Domains |
Protein: ENSMUSP00000142200
Gene: ENSMUSG00000063887
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:COesterase
|
29 |
626 |
1.2e-186 |
PFAM |
|
Pfam:Abhydrolase_3
|
196 |
309 |
3.7e-8 |
PFAM |
|
transmembrane domain
|
697 |
719 |
N/A |
INTRINSIC |
|
low complexity region
|
720 |
731 |
N/A |
INTRINSIC |
|
low complexity region
|
796 |
809 |
N/A |
INTRINSIC |
|
low complexity region
|
816 |
827 |
N/A |
INTRINSIC |
|
low complexity region
|
829 |
839 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000193603
|
| SMART Domains |
Protein: ENSMUSP00000142200
Gene: ENSMUSG00000063887
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:COesterase
|
29 |
626 |
1.2e-186 |
PFAM |
|
Pfam:Abhydrolase_3
|
196 |
309 |
3.7e-8 |
PFAM |
|
transmembrane domain
|
697 |
719 |
N/A |
INTRINSIC |
|
low complexity region
|
720 |
731 |
N/A |
INTRINSIC |
|
low complexity region
|
796 |
809 |
N/A |
INTRINSIC |
|
low complexity region
|
816 |
827 |
N/A |
INTRINSIC |
|
low complexity region
|
829 |
839 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000193603
|
| SMART Domains |
Protein: ENSMUSP00000142200
Gene: ENSMUSG00000063887
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:COesterase
|
29 |
626 |
1.2e-186 |
PFAM |
|
Pfam:Abhydrolase_3
|
196 |
309 |
3.7e-8 |
PFAM |
|
transmembrane domain
|
697 |
719 |
N/A |
INTRINSIC |
|
low complexity region
|
720 |
731 |
N/A |
INTRINSIC |
|
low complexity region
|
796 |
809 |
N/A |
INTRINSIC |
|
low complexity region
|
816 |
827 |
N/A |
INTRINSIC |
|
low complexity region
|
829 |
839 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.7%
|
| Validation Efficiency |
96% (73/76) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a knock-out allele are viable and fertile but display impaired NMDA receptor-mediated synaptic transmission onto CA1 pyramidal cells. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(4) : Targeted(3) Gene trapped(1)
|
| Other mutations in this stock |
Total: 77 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2610021A01Rik |
T |
A |
7: 41,275,837 (GRCm39) |
N513K |
possibly damaging |
Het |
| Actl6a |
T |
A |
3: 32,779,469 (GRCm39) |
I399N |
probably damaging |
Het |
| Adamts5 |
A |
G |
16: 85,666,971 (GRCm39) |
V507A |
probably damaging |
Het |
| Ap3d1 |
A |
G |
10: 80,554,918 (GRCm39) |
V469A |
probably benign |
Het |
| Arhgef4 |
G |
T |
1: 34,764,241 (GRCm39) |
|
probably null |
Het |
| Arhgef4 |
A |
T |
1: 34,849,576 (GRCm39) |
Q389L |
probably benign |
Het |
| Atad2 |
A |
G |
15: 57,980,194 (GRCm39) |
V106A |
possibly damaging |
Het |
| Azin2 |
T |
C |
4: 128,841,341 (GRCm39) |
E275G |
probably damaging |
Het |
| Bhlhe23 |
A |
G |
2: 180,418,143 (GRCm39) |
S132P |
probably damaging |
Het |
| Capn12 |
A |
G |
7: 28,581,243 (GRCm39) |
Y32C |
probably damaging |
Het |
| Celsr2 |
A |
T |
3: 108,321,349 (GRCm39) |
S488T |
probably benign |
Het |
| Cenpx |
A |
G |
11: 120,602,582 (GRCm39) |
V27A |
possibly damaging |
Het |
| Clca3a2 |
G |
A |
3: 144,778,005 (GRCm39) |
P760L |
probably benign |
Het |
| Clstn3 |
T |
C |
6: 124,408,571 (GRCm39) |
S951G |
probably benign |
Het |
| Clybl |
C |
A |
14: 122,621,670 (GRCm39) |
P286Q |
probably benign |
Het |
| Cmya5 |
T |
A |
13: 93,226,866 (GRCm39) |
M2741L |
probably benign |
Het |
| Cntnap2 |
G |
A |
6: 47,026,183 (GRCm39) |
G944E |
probably damaging |
Het |
| Col8a1 |
A |
C |
16: 57,447,283 (GRCm39) |
Y742* |
probably null |
Het |
| Crb1 |
T |
C |
1: 139,171,051 (GRCm39) |
K780E |
probably damaging |
Het |
| Crygc |
T |
A |
1: 65,112,376 (GRCm39) |
Y66F |
probably benign |
Het |
| Cyp2b9 |
G |
A |
7: 25,873,004 (GRCm39) |
G49E |
possibly damaging |
Het |
| D130043K22Rik |
T |
C |
13: 25,041,090 (GRCm39) |
S171P |
possibly damaging |
Het |
| Dhx36 |
T |
C |
3: 62,378,895 (GRCm39) |
I890V |
probably benign |
Het |
| Dpp9 |
C |
T |
17: 56,512,765 (GRCm39) |
G148S |
probably damaging |
Het |
| Eml6 |
G |
T |
11: 29,781,175 (GRCm39) |
S619Y |
probably damaging |
Het |
| Enpp4 |
A |
T |
17: 44,412,252 (GRCm39) |
L319* |
probably null |
Het |
| Esyt1 |
T |
C |
10: 128,361,356 (GRCm39) |
S113G |
probably benign |
Het |
| Fat1 |
A |
G |
8: 45,404,791 (GRCm39) |
D514G |
possibly damaging |
Het |
| Fbxo16 |
G |
A |
14: 65,524,594 (GRCm39) |
R38Q |
probably damaging |
Het |
| Fchsd1 |
A |
T |
18: 38,092,706 (GRCm39) |
M668K |
unknown |
Het |
| Gpr149 |
C |
T |
3: 62,511,093 (GRCm39) |
S302N |
probably benign |
Het |
| Gsap |
A |
G |
5: 21,433,064 (GRCm39) |
K258E |
probably benign |
Het |
| Helq |
C |
A |
5: 100,939,218 (GRCm39) |
V443F |
probably benign |
Het |
| Helq |
T |
A |
5: 100,939,219 (GRCm39) |
K442N |
probably damaging |
Het |
| Ighv1-37 |
T |
C |
12: 114,860,123 (GRCm39) |
E29G |
possibly damaging |
Het |
| Ighv1-9 |
C |
A |
12: 114,547,620 (GRCm39) |
M1I |
probably null |
Het |
| Itga6 |
T |
G |
2: 71,671,477 (GRCm39) |
F743V |
probably benign |
Het |
| Lpin1 |
C |
A |
12: 16,588,548 (GRCm39) |
D881Y |
|
Het |
| Lypd8 |
T |
A |
11: 58,273,640 (GRCm39) |
C40S |
possibly damaging |
Het |
| Macf1 |
C |
T |
4: 123,326,227 (GRCm39) |
R5092Q |
probably damaging |
Het |
| Mcm7 |
A |
G |
5: 138,166,593 (GRCm39) |
|
probably null |
Het |
| Micall2 |
G |
A |
5: 139,696,170 (GRCm39) |
T831I |
unknown |
Het |
| Myo18b |
A |
T |
5: 113,022,927 (GRCm39) |
M155K |
unknown |
Het |
| Nckap5 |
T |
A |
1: 125,867,928 (GRCm39) |
H201L |
unknown |
Het |
| Ndst2 |
A |
T |
14: 20,779,240 (GRCm39) |
D333E |
possibly damaging |
Het |
| Nup188 |
T |
G |
2: 30,232,397 (GRCm39) |
Y1483D |
probably benign |
Het |
| Or4c109 |
A |
C |
2: 88,818,057 (GRCm39) |
L163* |
probably null |
Het |
| Or52ae9 |
T |
A |
7: 103,390,319 (GRCm39) |
S43C |
probably benign |
Het |
| Or52n4b |
A |
C |
7: 108,144,664 (GRCm39) |
I311L |
probably benign |
Het |
| Or5p66 |
T |
A |
7: 107,885,526 (GRCm39) |
Y269F |
probably benign |
Het |
| Or8g33 |
T |
A |
9: 39,337,635 (GRCm39) |
H244L |
probably damaging |
Het |
| Peg3 |
A |
C |
7: 6,711,226 (GRCm39) |
I1332S |
possibly damaging |
Het |
| Piezo2 |
T |
C |
18: 63,154,372 (GRCm39) |
K2469R |
probably damaging |
Het |
| Pik3cg |
T |
C |
12: 32,247,312 (GRCm39) |
M804V |
probably damaging |
Het |
| Polq |
A |
T |
16: 36,869,011 (GRCm39) |
I794F |
possibly damaging |
Het |
| Rasgef1b |
A |
G |
5: 99,370,191 (GRCm39) |
V437A |
probably benign |
Het |
| Rdm1 |
T |
A |
11: 101,518,857 (GRCm39) |
D21E |
probably benign |
Het |
| Ripk4 |
G |
T |
16: 97,551,311 (GRCm39) |
Q219K |
possibly damaging |
Het |
| Ropn1l |
T |
C |
15: 31,441,471 (GRCm39) |
I217V |
|
Het |
| Sdf2 |
T |
C |
11: 78,136,858 (GRCm39) |
S13P |
unknown |
Het |
| Selenbp1 |
A |
G |
3: 94,847,079 (GRCm39) |
T202A |
probably benign |
Het |
| Slfn5 |
T |
C |
11: 82,850,933 (GRCm39) |
F410S |
possibly damaging |
Het |
| Srrm2 |
A |
G |
17: 24,039,880 (GRCm39) |
T2175A |
probably benign |
Het |
| St6galnac3 |
T |
C |
3: 153,117,360 (GRCm39) |
Y121C |
possibly damaging |
Het |
| Stat1 |
A |
G |
1: 52,184,337 (GRCm39) |
N417S |
probably benign |
Het |
| Tead1 |
T |
C |
7: 112,475,378 (GRCm39) |
F276L |
probably damaging |
Het |
| Teddm3 |
A |
T |
16: 20,971,737 (GRCm39) |
S277R |
probably benign |
Het |
| Tmc2 |
A |
G |
2: 130,103,317 (GRCm39) |
|
probably null |
Het |
| Tmem156 |
G |
A |
5: 65,231,127 (GRCm39) |
L248F |
probably damaging |
Het |
| Tnn |
T |
C |
1: 159,953,986 (GRCm39) |
S590G |
probably benign |
Het |
| Trmt44 |
A |
G |
5: 35,731,422 (GRCm39) |
|
probably null |
Het |
| Upp2 |
T |
A |
2: 58,668,022 (GRCm39) |
Y238* |
probably null |
Het |
| Usp32 |
T |
C |
11: 84,930,838 (GRCm39) |
T531A |
probably damaging |
Het |
| Vmn2r78 |
A |
T |
7: 86,569,431 (GRCm39) |
D108V |
probably benign |
Het |
| Wdfy3 |
G |
T |
5: 102,078,830 (GRCm39) |
A824E |
probably benign |
Het |
| Xylt1 |
T |
C |
7: 117,255,870 (GRCm39) |
V814A |
probably benign |
Het |
| Zfy1 |
C |
T |
Y: 732,990 (GRCm39) |
R281H |
unknown |
Het |
|
| Other mutations in Nlgn1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00510:Nlgn1
|
APN |
3 |
25,490,654 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL00543:Nlgn1
|
APN |
3 |
25,487,945 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00960:Nlgn1
|
APN |
3 |
25,966,861 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01533:Nlgn1
|
APN |
3 |
25,490,527 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
IGL02146:Nlgn1
|
APN |
3 |
25,966,846 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02616:Nlgn1
|
APN |
3 |
25,488,409 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03342:Nlgn1
|
APN |
3 |
26,187,411 (GRCm39) |
missense |
probably damaging |
1.00 |
|
ligation
|
UTSW |
3 |
25,490,199 (GRCm39) |
nonsense |
probably null |
|
|
G1citation:Nlgn1
|
UTSW |
3 |
26,187,796 (GRCm39) |
missense |
probably benign |
0.00 |
|
P0018:Nlgn1
|
UTSW |
3 |
25,490,741 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0010:Nlgn1
|
UTSW |
3 |
25,490,006 (GRCm39) |
splice site |
probably benign |
|
|
R0010:Nlgn1
|
UTSW |
3 |
25,490,006 (GRCm39) |
splice site |
probably benign |
|
|
R0123:Nlgn1
|
UTSW |
3 |
25,490,089 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0134:Nlgn1
|
UTSW |
3 |
25,490,089 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0294:Nlgn1
|
UTSW |
3 |
26,187,625 (GRCm39) |
missense |
probably benign |
0.23 |
|
R0798:Nlgn1
|
UTSW |
3 |
25,488,410 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1051:Nlgn1
|
UTSW |
3 |
25,966,869 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1116:Nlgn1
|
UTSW |
3 |
25,488,038 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1289:Nlgn1
|
UTSW |
3 |
25,488,400 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R1522:Nlgn1
|
UTSW |
3 |
25,490,073 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1550:Nlgn1
|
UTSW |
3 |
25,966,808 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1669:Nlgn1
|
UTSW |
3 |
25,490,298 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1853:Nlgn1
|
UTSW |
3 |
26,187,671 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R1856:Nlgn1
|
UTSW |
3 |
25,494,201 (GRCm39) |
nonsense |
probably null |
|
|
R1935:Nlgn1
|
UTSW |
3 |
26,385,939 (GRCm39) |
utr 5 prime |
probably benign |
|
|
R1936:Nlgn1
|
UTSW |
3 |
26,385,939 (GRCm39) |
utr 5 prime |
probably benign |
|
|
R1952:Nlgn1
|
UTSW |
3 |
25,490,464 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1953:Nlgn1
|
UTSW |
3 |
25,490,464 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2004:Nlgn1
|
UTSW |
3 |
25,488,034 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2114:Nlgn1
|
UTSW |
3 |
26,187,414 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2116:Nlgn1
|
UTSW |
3 |
26,187,414 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2198:Nlgn1
|
UTSW |
3 |
25,487,925 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2994:Nlgn1
|
UTSW |
3 |
25,490,162 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3056:Nlgn1
|
UTSW |
3 |
25,487,860 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R4190:Nlgn1
|
UTSW |
3 |
25,488,062 (GRCm39) |
missense |
probably benign |
|
|
R4196:Nlgn1
|
UTSW |
3 |
25,488,556 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4613:Nlgn1
|
UTSW |
3 |
25,490,186 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4654:Nlgn1
|
UTSW |
3 |
26,187,850 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R4757:Nlgn1
|
UTSW |
3 |
25,490,507 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R4757:Nlgn1
|
UTSW |
3 |
25,490,332 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4815:Nlgn1
|
UTSW |
3 |
25,490,194 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4884:Nlgn1
|
UTSW |
3 |
25,966,838 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4966:Nlgn1
|
UTSW |
3 |
25,974,401 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R5119:Nlgn1
|
UTSW |
3 |
25,487,958 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5842:Nlgn1
|
UTSW |
3 |
26,187,892 (GRCm39) |
splice site |
probably null |
|
|
R6218:Nlgn1
|
UTSW |
3 |
25,490,257 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6397:Nlgn1
|
UTSW |
3 |
25,487,827 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R6500:Nlgn1
|
UTSW |
3 |
25,488,094 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R6822:Nlgn1
|
UTSW |
3 |
26,187,796 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6846:Nlgn1
|
UTSW |
3 |
25,490,506 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7047:Nlgn1
|
UTSW |
3 |
25,490,199 (GRCm39) |
nonsense |
probably null |
|
|
R7147:Nlgn1
|
UTSW |
3 |
26,187,509 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7754:Nlgn1
|
UTSW |
3 |
25,488,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7886:Nlgn1
|
UTSW |
3 |
25,490,071 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8184:Nlgn1
|
UTSW |
3 |
25,490,363 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8261:Nlgn1
|
UTSW |
3 |
25,487,816 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R8304:Nlgn1
|
UTSW |
3 |
26,187,534 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8364:Nlgn1
|
UTSW |
3 |
25,490,140 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8503:Nlgn1
|
UTSW |
3 |
26,187,522 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9035:Nlgn1
|
UTSW |
3 |
25,488,595 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9053:Nlgn1
|
UTSW |
3 |
25,488,607 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9268:Nlgn1
|
UTSW |
3 |
25,490,548 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9368:Nlgn1
|
UTSW |
3 |
25,488,622 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9492:Nlgn1
|
UTSW |
3 |
25,488,480 (GRCm39) |
nonsense |
probably null |
|
|
R9596:Nlgn1
|
UTSW |
3 |
25,488,587 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9647:Nlgn1
|
UTSW |
3 |
25,488,182 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9697:Nlgn1
|
UTSW |
3 |
25,494,035 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
Z1176:Nlgn1
|
UTSW |
3 |
25,490,768 (GRCm39) |
missense |
probably benign |
0.12 |
|
| Predicted Primers |
PCR Primer
(F):5'- CATCAGTGATCAGTGCCTTCATTAC -3'
(R):5'- GTTGGGGATAACTATAATTGCCAACC -3'
Sequencing Primer
(F):5'- AGTGATCAGTGCCTTCATTACCTTTC -3'
(R):5'- CCATTTATTTTGCAGATATTCGGGAC -3'
|
| Posted On |
2022-02-07 |
Incidental Mutation