Incidental Mutation 'IGL01385:Vmn1r238'
ID79001
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r238
Ensembl Gene ENSMUSG00000091539
Gene Namevomeronasal 1 receptor, 238
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.067) question?
Stock #IGL01385
Quality Score
Status
Chromosome18
Chromosomal Location3122492-3123412 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) G to T at 3122770 bp
ZygosityHeterozygous
Amino Acid Change Glutamine to Lysine at position 215 (Q215K)
Ref Sequence ENSEMBL: ENSMUSP00000129804 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000165255]
Predicted Effect possibly damaging
Transcript: ENSMUST00000165255
AA Change: Q215K

PolyPhen 2 Score 0.828 (Sensitivity: 0.84; Specificity: 0.93)
SMART Domains Protein: ENSMUSP00000129804
Gene: ENSMUSG00000091539
AA Change: Q215K

DomainStartEndE-ValueType
Pfam:TAS2R 7 302 5.3e-8 PFAM
Pfam:7tm_1 27 292 8.8e-7 PFAM
Pfam:V1R 34 298 1.9e-33 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 31 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1700016C15Rik G A 1: 177,741,074 G46R probably benign Het
Ablim1 A T 19: 57,068,914 S292R probably damaging Het
Adamts19 A G 18: 58,972,779 T749A probably damaging Het
Agap2 A T 10: 127,087,996 I747F unknown Het
Arhgap35 T A 7: 16,564,474 N222I probably damaging Het
Atp10b A G 11: 43,234,429 E1074G probably damaging Het
Brd3 T C 2: 27,464,089 T4A possibly damaging Het
Col6a6 A G 9: 105,783,666 S415P probably damaging Het
Dennd2a A G 6: 39,523,136 V165A probably damaging Het
Dnm1l T A 16: 16,341,453 E95V probably damaging Het
Dock9 A G 14: 121,580,583 Y1609H possibly damaging Het
Esm1 A C 13: 113,216,682 E166A possibly damaging Het
F2rl2 A C 13: 95,701,328 I294L probably benign Het
Gstt3 A G 10: 75,774,988 S187P probably benign Het
Katna1 T C 10: 7,752,810 C268R probably damaging Het
Mbd5 T A 2: 49,250,221 C66S possibly damaging Het
Naa35 G A 13: 59,601,066 E167K probably damaging Het
Olfr1330 T C 4: 118,893,551 L156S probably benign Het
Osbpl2 A G 2: 180,137,080 N2S probably benign Het
Parp6 T C 9: 59,630,612 probably benign Het
Pcdhb5 T A 18: 37,322,214 V549E probably benign Het
Pcnx4 T C 12: 72,573,746 L780P probably damaging Het
Plcb3 A T 19: 6,957,908 D851E probably benign Het
Ppfia2 A G 10: 106,913,699 S1149G probably damaging Het
Prkca A G 11: 107,978,352 V469A probably damaging Het
Ryr1 A T 7: 29,056,985 V3468D probably damaging Het
Stxbp4 A G 11: 90,540,248 V412A possibly damaging Het
Wdr11 A G 7: 129,607,913 M482V probably benign Het
Wdr72 T C 9: 74,179,506 probably benign Het
Xirp2 T C 2: 67,509,677 L754P probably damaging Het
Zmym6 G A 4: 127,124,106 G1135S probably benign Het
Other mutations in Vmn1r238
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00427:Vmn1r238 APN 18 3123243 missense probably benign 0.01
IGL02716:Vmn1r238 APN 18 3123124 missense probably damaging 1.00
R1219:Vmn1r238 UTSW 18 3123135 missense possibly damaging 0.81
R1568:Vmn1r238 UTSW 18 3123358 missense probably benign 0.00
R1864:Vmn1r238 UTSW 18 3123040 nonsense probably null
R3024:Vmn1r238 UTSW 18 3123305 missense probably benign 0.13
R4291:Vmn1r238 UTSW 18 3123214 nonsense probably null
R4304:Vmn1r238 UTSW 18 3123040 nonsense probably null
R4586:Vmn1r238 UTSW 18 3123294 missense probably damaging 1.00
R4664:Vmn1r238 UTSW 18 3123300 missense probably damaging 0.99
R5123:Vmn1r238 UTSW 18 3123243 missense probably benign
R5430:Vmn1r238 UTSW 18 3122521 missense possibly damaging 0.63
R5834:Vmn1r238 UTSW 18 3123168 missense probably benign
R7186:Vmn1r238 UTSW 18 3122661 missense probably damaging 0.99
R7206:Vmn1r238 UTSW 18 3122623 missense possibly damaging 0.94
R7308:Vmn1r238 UTSW 18 3122875 missense probably benign 0.09
R7346:Vmn1r238 UTSW 18 3123151 missense probably damaging 1.00
R7467:Vmn1r238 UTSW 18 3123393 missense probably benign 0.10
R7571:Vmn1r238 UTSW 18 3122721 missense probably damaging 1.00
R7808:Vmn1r238 UTSW 18 3123033 missense probably benign 0.03
Z1177:Vmn1r238 UTSW 18 3122505 missense probably benign 0.00
Posted On2013-11-05