Incidental Mutation 'R1529:Nisch'
| ID |
166489 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Nisch
|
| Ensembl Gene |
ENSMUSG00000021910 |
| Gene Name |
nischarin |
| Synonyms |
1200007D05Rik, edsn, 3202002H23Rik |
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1529 (G1)
|
| Quality Score |
170 |
|
Status
|
Not validated
|
| Chromosome |
14 |
| Chromosomal Location |
30892885-30928783 bp(-) (GRCm39) |
| Type of Mutation |
unclassified |
| DNA Base Change (assembly) |
C to T
at 30902895 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000132413
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000022469]
[ENSMUST00000164989]
[ENSMUST00000165981]
[ENSMUST00000169906]
[ENSMUST00000168206]
[ENSMUST00000172142]
|
| AlphaFold |
Q80TM9 |
| Predicted Effect |
unknown
Transcript: ENSMUST00000022469
AA Change: V515I
|
| SMART Domains |
Protein: ENSMUSP00000022469
Gene: ENSMUSG00000021910
AA Change: V515I
| Domain | Start | End | E-Value | Type |
|---|
|
PX
|
15 |
119 |
2.17e-26 |
SMART |
|
PDB:4PQ8|A
|
287 |
420 |
9e-8 |
PDB |
|
SCOP:d1h6ta2
|
291 |
421 |
6e-29 |
SMART |
|
Blast:LRR
|
311 |
332 |
5e-6 |
BLAST |
|
Blast:LRR
|
333 |
355 |
6e-6 |
BLAST |
|
Blast:LRR
|
378 |
403 |
5e-7 |
BLAST |
|
Blast:LRR
|
403 |
429 |
6e-7 |
BLAST |
|
low complexity region
|
489 |
501 |
N/A |
INTRINSIC |
|
low complexity region
|
517 |
534 |
N/A |
INTRINSIC |
|
coiled coil region
|
625 |
650 |
N/A |
INTRINSIC |
|
low complexity region
|
662 |
695 |
N/A |
INTRINSIC |
|
low complexity region
|
1038 |
1069 |
N/A |
INTRINSIC |
|
low complexity region
|
1081 |
1193 |
N/A |
INTRINSIC |
|
low complexity region
|
1491 |
1509 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000163552
|
| SMART Domains |
Protein: ENSMUSP00000131689
Gene: ENSMUSG00000021910
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
96 |
127 |
N/A |
INTRINSIC |
|
low complexity region
|
139 |
242 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000163846
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000164000
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000164956
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000164989
|
| SMART Domains |
Protein: ENSMUSP00000126982
Gene: ENSMUSG00000021910
| Domain | Start | End | E-Value | Type |
|---|
|
PX
|
15 |
119 |
2.17e-26 |
SMART |
|
Pfam:LRR_4
|
289 |
332 |
3.2e-8 |
PFAM |
|
Pfam:LRR_1
|
290 |
311 |
2.9e-3 |
PFAM |
|
Pfam:LRR_1
|
313 |
332 |
4.2e-2 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000165981
|
| SMART Domains |
Protein: ENSMUSP00000130210
Gene: ENSMUSG00000021910
| Domain | Start | End | E-Value | Type |
|---|
|
PX
|
15 |
119 |
2.17e-26 |
SMART |
|
Pfam:LRR_7
|
289 |
305 |
7.4e-2 |
PFAM |
|
Pfam:LRR_6
|
289 |
309 |
3.8e-2 |
PFAM |
|
Pfam:LRR_4
|
289 |
333 |
5.9e-8 |
PFAM |
|
Pfam:LRR_8
|
289 |
346 |
6.8e-10 |
PFAM |
|
Pfam:LRR_1
|
290 |
311 |
4.4e-3 |
PFAM |
|
Pfam:LRR_8
|
312 |
369 |
7.3e-9 |
PFAM |
|
Pfam:LRR_1
|
313 |
333 |
1.8e-2 |
PFAM |
|
Pfam:LRR_4
|
329 |
377 |
2.3e-8 |
PFAM |
|
Pfam:LRR_6
|
333 |
354 |
2e-3 |
PFAM |
|
Pfam:LRR_7
|
334 |
350 |
1.9e-1 |
PFAM |
|
Pfam:LRR_1
|
335 |
354 |
1.2e-2 |
PFAM |
|
Blast:LRR
|
378 |
403 |
1e-6 |
BLAST |
|
Blast:LRR
|
403 |
429 |
1e-7 |
BLAST |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000167223
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000169906
|
| SMART Domains |
Protein: ENSMUSP00000129268
Gene: ENSMUSG00000021910
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
5 |
22 |
N/A |
INTRINSIC |
|
coiled coil region
|
113 |
138 |
N/A |
INTRINSIC |
|
low complexity region
|
150 |
183 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000168206
AA Change: V270I
|
| SMART Domains |
Protein: ENSMUSP00000132842
Gene: ENSMUSG00000021910
AA Change: V270I
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:LRR_8
|
44 |
101 |
3.9e-9 |
PFAM |
|
Pfam:LRR_1
|
45 |
66 |
2.6e-2 |
PFAM |
|
Pfam:LRR_6
|
88 |
109 |
1.1e-2 |
PFAM |
|
Pfam:LRR_4
|
89 |
132 |
6.5e-8 |
PFAM |
|
Pfam:LRR_1
|
90 |
109 |
6.9e-2 |
PFAM |
|
Blast:LRR
|
133 |
158 |
4e-7 |
BLAST |
|
Blast:LRR
|
158 |
184 |
6e-7 |
BLAST |
|
low complexity region
|
244 |
256 |
N/A |
INTRINSIC |
|
low complexity region
|
272 |
289 |
N/A |
INTRINSIC |
|
coiled coil region
|
380 |
405 |
N/A |
INTRINSIC |
|
low complexity region
|
417 |
450 |
N/A |
INTRINSIC |
|
low complexity region
|
793 |
824 |
N/A |
INTRINSIC |
|
low complexity region
|
836 |
948 |
N/A |
INTRINSIC |
|
low complexity region
|
1246 |
1264 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000170253
|
| SMART Domains |
Protein: ENSMUSP00000129547
Gene: ENSMUSG00000021910
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1dcea3
|
2 |
86 |
3e-11 |
SMART |
|
Blast:LRR
|
13 |
34 |
1e-5 |
BLAST |
|
Blast:LRR
|
35 |
60 |
1e-7 |
BLAST |
|
Blast:LRR
|
60 |
86 |
2e-8 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000170436
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000170343
|
| SMART Domains |
Protein: ENSMUSP00000130246
Gene: ENSMUSG00000021910
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:LRR_8
|
74 |
131 |
2.3e-8 |
PFAM |
|
Blast:LRR
|
140 |
165 |
7e-7 |
BLAST |
|
Blast:LRR
|
165 |
191 |
6e-8 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000172142
|
| SMART Domains |
Protein: ENSMUSP00000132413
Gene: ENSMUSG00000021910
| Domain | Start | End | E-Value | Type |
|---|
|
PX
|
15 |
119 |
2.17e-26 |
SMART |
|
Pfam:LRR_7
|
289 |
305 |
8.2e-2 |
PFAM |
|
Pfam:LRR_6
|
289 |
309 |
4.2e-2 |
PFAM |
|
Pfam:LRR_4
|
289 |
333 |
6.6e-8 |
PFAM |
|
Pfam:LRR_8
|
289 |
346 |
7.6e-10 |
PFAM |
|
Pfam:LRR_1
|
290 |
311 |
4.9e-3 |
PFAM |
|
Pfam:LRR_8
|
312 |
369 |
7.7e-9 |
PFAM |
|
Pfam:LRR_1
|
313 |
333 |
2e-2 |
PFAM |
|
Pfam:LRR_4
|
329 |
377 |
2.7e-8 |
PFAM |
|
Pfam:LRR_6
|
333 |
354 |
2.2e-3 |
PFAM |
|
Pfam:LRR_7
|
334 |
350 |
2.1e-1 |
PFAM |
|
Pfam:LRR_1
|
335 |
354 |
1.3e-2 |
PFAM |
|
Blast:LRR
|
378 |
403 |
1e-6 |
BLAST |
|
Blast:LRR
|
403 |
429 |
1e-7 |
BLAST |
|
low complexity region
|
489 |
501 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000168451
|
| SMART Domains |
Protein: ENSMUSP00000132912
Gene: ENSMUSG00000021910
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:PX
|
4 |
53 |
5.5e-8 |
PFAM |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.8%
- 20x: 94.3%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Mice homozygous for either a knock-out or hypomorphic allele exhibit hearing loss associated with increased susceptibility to otitis media. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 82 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aadacl2fm3 |
T |
C |
3: 59,768,533 (GRCm39) |
I21T |
probably benign |
Het |
| Adam11 |
T |
C |
11: 102,665,939 (GRCm39) |
|
probably null |
Het |
| Amd1 |
A |
T |
10: 40,166,501 (GRCm39) |
M194K |
probably benign |
Het |
| Ap1b1 |
T |
G |
11: 4,989,547 (GRCm39) |
F793C |
probably damaging |
Het |
| Arfgef3 |
G |
A |
10: 18,488,970 (GRCm39) |
R1292* |
probably null |
Het |
| Arhgef5 |
C |
A |
6: 43,256,449 (GRCm39) |
H1186N |
probably damaging |
Het |
| Atad1 |
A |
G |
19: 32,684,321 (GRCm39) |
F26L |
probably benign |
Het |
| Atg2b |
C |
T |
12: 105,627,392 (GRCm39) |
V532I |
probably benign |
Het |
| Atp2b4 |
A |
G |
1: 133,645,726 (GRCm39) |
F943L |
probably damaging |
Het |
| Atp7b |
G |
A |
8: 22,518,740 (GRCm39) |
L21F |
possibly damaging |
Het |
| Ccdc9b |
T |
A |
2: 118,592,241 (GRCm39) |
|
probably null |
Het |
| Cenpf |
A |
T |
1: 189,392,235 (GRCm39) |
D532E |
probably benign |
Het |
| Cimip3 |
G |
A |
17: 47,724,815 (GRCm39) |
S102L |
probably benign |
Het |
| Ckmt2 |
A |
T |
13: 92,009,320 (GRCm39) |
D202E |
probably benign |
Het |
| Crim1 |
A |
C |
17: 78,675,383 (GRCm39) |
K864T |
probably benign |
Het |
| Ctnnd2 |
A |
G |
15: 30,887,267 (GRCm39) |
R765G |
possibly damaging |
Het |
| Ddx10 |
T |
A |
9: 53,028,499 (GRCm39) |
R802* |
probably null |
Het |
| Dnah7b |
T |
A |
1: 46,216,441 (GRCm39) |
F1152L |
probably damaging |
Het |
| Dsg1c |
T |
C |
18: 20,415,080 (GRCm39) |
L659P |
probably damaging |
Het |
| Dzank1 |
A |
G |
2: 144,324,108 (GRCm39) |
F577L |
probably benign |
Het |
| Eci3 |
T |
C |
13: 35,140,903 (GRCm39) |
D93G |
probably benign |
Het |
| Ecpas |
T |
C |
4: 58,832,701 (GRCm39) |
|
probably null |
Het |
| Ep400 |
C |
A |
5: 110,887,311 (GRCm39) |
V591L |
probably benign |
Het |
| Fgd3 |
T |
C |
13: 49,420,170 (GRCm39) |
N569S |
probably benign |
Het |
| Ghsr |
T |
A |
3: 27,426,631 (GRCm39) |
V229E |
probably damaging |
Het |
| Gna15 |
T |
A |
10: 81,345,176 (GRCm39) |
I230F |
probably damaging |
Het |
| Gnl2 |
A |
G |
4: 124,940,099 (GRCm39) |
S324G |
probably damaging |
Het |
| Grid1 |
T |
C |
14: 35,031,250 (GRCm39) |
V281A |
probably benign |
Het |
| Hebp2 |
G |
A |
10: 18,421,509 (GRCm39) |
A12V |
possibly damaging |
Het |
| Hfm1 |
T |
C |
5: 107,000,989 (GRCm39) |
D1254G |
probably benign |
Het |
| Hif3a |
A |
C |
7: 16,776,564 (GRCm39) |
S459A |
probably benign |
Het |
| Hnrnpl |
T |
A |
7: 28,513,348 (GRCm39) |
N149K |
possibly damaging |
Het |
| Hoxc10 |
A |
T |
15: 102,875,635 (GRCm39) |
S115C |
probably damaging |
Het |
| Hycc2 |
A |
T |
1: 58,578,766 (GRCm39) |
D261E |
probably benign |
Het |
| Ifnab |
T |
C |
4: 88,609,292 (GRCm39) |
D58G |
possibly damaging |
Het |
| Itfg1 |
T |
C |
8: 86,537,243 (GRCm39) |
T195A |
probably benign |
Het |
| Itpr3 |
T |
A |
17: 27,324,459 (GRCm39) |
|
probably null |
Het |
| Iws1 |
A |
G |
18: 32,213,334 (GRCm39) |
D254G |
probably benign |
Het |
| Kl |
C |
A |
5: 150,912,406 (GRCm39) |
D718E |
probably benign |
Het |
| Lrit2 |
A |
G |
14: 36,790,784 (GRCm39) |
I154M |
probably benign |
Het |
| Lrp2 |
T |
C |
2: 69,353,526 (GRCm39) |
D578G |
probably damaging |
Het |
| Lss |
T |
G |
10: 76,372,123 (GRCm39) |
Y159* |
probably null |
Het |
| Mab21l1 |
C |
A |
3: 55,691,254 (GRCm39) |
Y280* |
probably null |
Het |
| Maf |
A |
T |
8: 116,419,909 (GRCm39) |
S378T |
probably benign |
Het |
| Mast2 |
C |
T |
4: 116,287,716 (GRCm39) |
V59I |
probably benign |
Het |
| Nova2 |
A |
T |
7: 18,691,479 (GRCm39) |
N139Y |
probably damaging |
Het |
| Nup210 |
C |
A |
6: 91,013,358 (GRCm39) |
D434Y |
probably damaging |
Het |
| Nvl |
C |
T |
1: 180,936,724 (GRCm39) |
|
probably null |
Het |
| Or11g27 |
T |
C |
14: 50,771,159 (GRCm39) |
S97P |
possibly damaging |
Het |
| Or51g2 |
A |
G |
7: 102,623,086 (GRCm39) |
Y38H |
probably damaging |
Het |
| Or56b1 |
A |
G |
7: 104,285,696 (GRCm39) |
T272A |
probably benign |
Het |
| Or8k18 |
A |
T |
2: 86,085,585 (GRCm39) |
Y151N |
probably damaging |
Het |
| Or8k3b |
A |
G |
2: 86,520,677 (GRCm39) |
V214A |
possibly damaging |
Het |
| Pbx3 |
T |
C |
2: 34,094,871 (GRCm39) |
Y255C |
probably damaging |
Het |
| Pcyt1a |
G |
A |
16: 32,270,611 (GRCm39) |
E27K |
possibly damaging |
Het |
| Pex6 |
A |
T |
17: 47,024,990 (GRCm39) |
T348S |
probably benign |
Het |
| Phf21b |
A |
G |
15: 84,681,597 (GRCm39) |
I251T |
probably damaging |
Het |
| Pkd2l2 |
T |
C |
18: 34,563,755 (GRCm39) |
I490T |
probably damaging |
Het |
| Pla2g12a |
T |
A |
3: 129,672,534 (GRCm39) |
L56Q |
probably damaging |
Het |
| Plk4 |
A |
G |
3: 40,760,971 (GRCm39) |
T434A |
probably benign |
Het |
| Ptpn13 |
A |
G |
5: 103,711,998 (GRCm39) |
N1632S |
probably benign |
Het |
| Rfpl4 |
C |
T |
7: 5,113,711 (GRCm39) |
V151M |
probably damaging |
Het |
| Rpain |
G |
C |
11: 70,865,741 (GRCm39) |
E169Q |
probably damaging |
Het |
| Samd8 |
T |
A |
14: 21,825,227 (GRCm39) |
V124D |
possibly damaging |
Het |
| Sdk2 |
C |
T |
11: 113,729,472 (GRCm39) |
|
silent |
Het |
| Slc12a1 |
C |
T |
2: 125,032,215 (GRCm39) |
T622I |
probably damaging |
Het |
| Slc17a3 |
T |
A |
13: 24,029,428 (GRCm39) |
V67D |
probably damaging |
Het |
| Slc41a3 |
G |
T |
6: 90,621,198 (GRCm39) |
V387L |
probably damaging |
Het |
| Slitrk1 |
T |
A |
14: 109,150,709 (GRCm39) |
M1L |
probably benign |
Het |
| Stat4 |
T |
C |
1: 52,050,952 (GRCm39) |
W4R |
probably damaging |
Het |
| Tas2r126 |
A |
G |
6: 42,411,502 (GRCm39) |
T12A |
probably benign |
Het |
| Tbc1d24 |
A |
G |
17: 24,404,953 (GRCm39) |
C64R |
probably damaging |
Het |
| Tcaf2 |
T |
C |
6: 42,606,440 (GRCm39) |
S505G |
probably benign |
Het |
| Tiam2 |
T |
C |
17: 3,566,978 (GRCm39) |
V1506A |
probably benign |
Het |
| Tmem9b |
A |
C |
7: 109,336,156 (GRCm39) |
S163A |
probably benign |
Het |
| Tmtc2 |
G |
A |
10: 105,139,519 (GRCm39) |
S669L |
probably damaging |
Het |
| Tnpo3 |
A |
T |
6: 29,560,220 (GRCm39) |
I641K |
possibly damaging |
Het |
| Ttn |
C |
T |
2: 76,565,711 (GRCm39) |
A28214T |
probably damaging |
Het |
| Utp11 |
G |
A |
4: 124,577,032 (GRCm39) |
A113V |
probably benign |
Het |
| Utp20 |
G |
A |
10: 88,588,868 (GRCm39) |
R2434C |
probably damaging |
Het |
| Vmn1r60 |
A |
T |
7: 5,547,902 (GRCm39) |
I66N |
probably benign |
Het |
| Zeb2 |
T |
C |
2: 44,887,206 (GRCm39) |
E572G |
probably damaging |
Het |
|
| Other mutations in Nisch |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01782:Nisch
|
APN |
14 |
30,898,596 (GRCm39) |
unclassified |
probably benign |
|
|
IGL01934:Nisch
|
APN |
14 |
30,898,696 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02201:Nisch
|
APN |
14 |
30,909,051 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02964:Nisch
|
APN |
14 |
30,902,769 (GRCm39) |
unclassified |
probably benign |
|
|
IGL03340:Nisch
|
APN |
14 |
30,895,101 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0092:Nisch
|
UTSW |
14 |
30,913,410 (GRCm39) |
unclassified |
probably benign |
|
|
R0119:Nisch
|
UTSW |
14 |
30,893,881 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0196:Nisch
|
UTSW |
14 |
30,925,351 (GRCm39) |
unclassified |
probably benign |
|
|
R0299:Nisch
|
UTSW |
14 |
30,893,881 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0452:Nisch
|
UTSW |
14 |
30,899,421 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R1643:Nisch
|
UTSW |
14 |
30,895,125 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1656:Nisch
|
UTSW |
14 |
30,899,228 (GRCm39) |
unclassified |
probably benign |
|
|
R1663:Nisch
|
UTSW |
14 |
30,913,478 (GRCm39) |
unclassified |
probably benign |
|
|
R1676:Nisch
|
UTSW |
14 |
30,902,859 (GRCm39) |
unclassified |
probably benign |
|
|
R1750:Nisch
|
UTSW |
14 |
30,896,839 (GRCm39) |
unclassified |
probably benign |
|
|
R1799:Nisch
|
UTSW |
14 |
30,899,228 (GRCm39) |
unclassified |
probably benign |
|
|
R1824:Nisch
|
UTSW |
14 |
30,898,389 (GRCm39) |
unclassified |
probably benign |
|
|
R1876:Nisch
|
UTSW |
14 |
30,895,594 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2107:Nisch
|
UTSW |
14 |
30,894,097 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2117:Nisch
|
UTSW |
14 |
30,899,242 (GRCm39) |
unclassified |
probably benign |
|
|
R2276:Nisch
|
UTSW |
14 |
30,898,803 (GRCm39) |
unclassified |
probably benign |
|
|
R2402:Nisch
|
UTSW |
14 |
30,906,971 (GRCm39) |
intron |
probably benign |
|
|
R3703:Nisch
|
UTSW |
14 |
30,898,702 (GRCm39) |
unclassified |
probably benign |
|
|
R3704:Nisch
|
UTSW |
14 |
30,898,702 (GRCm39) |
unclassified |
probably benign |
|
|
R3705:Nisch
|
UTSW |
14 |
30,898,702 (GRCm39) |
unclassified |
probably benign |
|
|
R3897:Nisch
|
UTSW |
14 |
30,912,957 (GRCm39) |
unclassified |
probably benign |
|
|
R4024:Nisch
|
UTSW |
14 |
30,898,776 (GRCm39) |
unclassified |
probably benign |
|
|
R4412:Nisch
|
UTSW |
14 |
30,908,615 (GRCm39) |
intron |
probably benign |
|
|
R4752:Nisch
|
UTSW |
14 |
30,914,545 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4832:Nisch
|
UTSW |
14 |
30,899,587 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R5009:Nisch
|
UTSW |
14 |
30,909,186 (GRCm39) |
unclassified |
probably benign |
|
|
R5043:Nisch
|
UTSW |
14 |
30,898,422 (GRCm39) |
unclassified |
probably benign |
|
|
R5062:Nisch
|
UTSW |
14 |
30,894,397 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5254:Nisch
|
UTSW |
14 |
30,928,524 (GRCm39) |
splice site |
probably null |
|
|
R5754:Nisch
|
UTSW |
14 |
30,913,373 (GRCm39) |
unclassified |
probably benign |
|
|
R5906:Nisch
|
UTSW |
14 |
30,893,985 (GRCm39) |
splice site |
probably null |
|
|
R5930:Nisch
|
UTSW |
14 |
30,895,102 (GRCm39) |
missense |
probably benign |
0.11 |
|
R6246:Nisch
|
UTSW |
14 |
30,894,516 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6258:Nisch
|
UTSW |
14 |
30,899,085 (GRCm39) |
unclassified |
probably benign |
|
|
R6260:Nisch
|
UTSW |
14 |
30,899,085 (GRCm39) |
unclassified |
probably benign |
|
|
R6327:Nisch
|
UTSW |
14 |
30,893,444 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R6671:Nisch
|
UTSW |
14 |
30,926,420 (GRCm39) |
unclassified |
probably benign |
|
|
R6874:Nisch
|
UTSW |
14 |
30,898,641 (GRCm39) |
unclassified |
probably benign |
|
|
R6887:Nisch
|
UTSW |
14 |
30,907,301 (GRCm39) |
unclassified |
probably benign |
|
|
R7273:Nisch
|
UTSW |
14 |
30,896,364 (GRCm39) |
missense |
unknown |
|
|
R7401:Nisch
|
UTSW |
14 |
30,928,537 (GRCm39) |
missense |
probably benign |
0.18 |
|
R7423:Nisch
|
UTSW |
14 |
30,893,658 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7822:Nisch
|
UTSW |
14 |
30,896,608 (GRCm39) |
unclassified |
probably benign |
|
|
R7870:Nisch
|
UTSW |
14 |
30,894,052 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7887:Nisch
|
UTSW |
14 |
30,898,652 (GRCm39) |
nonsense |
probably null |
|
|
R8215:Nisch
|
UTSW |
14 |
30,908,658 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R8672:Nisch
|
UTSW |
14 |
30,895,093 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9082:Nisch
|
UTSW |
14 |
30,899,331 (GRCm39) |
missense |
unknown |
|
|
R9134:Nisch
|
UTSW |
14 |
30,896,637 (GRCm39) |
unclassified |
probably benign |
|
|
R9153:Nisch
|
UTSW |
14 |
30,896,782 (GRCm39) |
missense |
unknown |
|
|
R9240:Nisch
|
UTSW |
14 |
30,906,988 (GRCm39) |
missense |
unknown |
|
|
R9652:Nisch
|
UTSW |
14 |
30,893,628 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9653:Nisch
|
UTSW |
14 |
30,893,628 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9663:Nisch
|
UTSW |
14 |
30,895,625 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9667:Nisch
|
UTSW |
14 |
30,895,646 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0027:Nisch
|
UTSW |
14 |
30,909,041 (GRCm39) |
unclassified |
probably benign |
|
|
Z1177:Nisch
|
UTSW |
14 |
30,899,395 (GRCm39) |
frame shift |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- AAGAGAAAGTACTGCCTGCTCCCG -3'
(R):5'- TCCAAGGGCAAAGCATCTTACTGAG -3'
Sequencing Primer
(F):5'- CTTGGTCTATGACCCAACTAGAG -3'
(R):5'- CTGAGGAGTTACTCAATTACTGCC -3'
|
| Posted On |
2014-04-13 |
Incidental Mutation