Mutagenetix > Incidental Mutation

Incidental Mutation 'R5436:Fat3'

428356

Institutional Source

Beutler Lab

Gene Symbol

Fat3

Ensembl Gene

ENSMUSG00000074505

Gene Name

FAT atypical cadherin 3

Synonyms

9430076A06Rik, D430038H04Rik, LOC382129, LOC234973

MMRRC Submission

043001-MU

Accession Numbers

Genbank: NM_001080814; MGI: 2444314

Essential gene?

Possibly non essential (E-score: 0.466) question?

Stock #

R5436 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

15910189-16501285 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to C at 15960514 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Valine to Glycine at position 3527 (V3527G)

Ref Sequence

ENSEMBL: ENSMUSP00000148968 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000082170] [ENSMUST00000217308]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000082170
AA Change: V3527G

PolyPhen 2 Score 0.023 (Sensitivity: 0.95; Specificity: 0.81)

SMART Domains

Protein: ENSMUSP00000080808
Gene: ENSMUSG00000074505
AA Change: V3527G

Domain	Start	End	E-Value	Type
signal peptide	1	27	N/A	INTRINSIC
CA	65	151	3e-7	SMART
CA	175	259	8.9e-22	SMART
CA	280	368	8.9e-4	SMART
CA	389	465	2.6e-11	SMART
CA	489	571	2e-29	SMART
low complexity region	684	697	N/A	INTRINSIC
CA	743	824	1e-24	SMART
low complexity region	830	840	N/A	INTRINSIC
CA	848	929	7.6e-26	SMART
CA	953	1034	1.5e-25	SMART
CA	1060	1141	6.6e-32	SMART
CA	1165	1247	1.5e-30	SMART
CA	1273	1349	1.8e-8	SMART
CA	1375	1453	2.9e-12	SMART
CA	1477	1559	3e-22	SMART
CA	1583	1664	3.1e-16	SMART
CA	1688	1762	4.2e-22	SMART
CA	1793	1876	2.5e-26	SMART
CA	1900	1975	1.5e-8	SMART
low complexity region	1983	1994	N/A	INTRINSIC
CA	1999	2077	1.4e-18	SMART
CA	2101	2179	6.6e-10	SMART
CA	2203	2280	4.9e-19	SMART
CA	2304	2387	4.3e-29	SMART
CA	2411	2489	4.2e-11	SMART
CA	2513	2593	2.8e-22	SMART
CA	2617	2701	4.3e-10	SMART
CA	2719	2807	2.5e-7	SMART
CA	2831	2917	3.3e-27	SMART
CA	2941	3022	9.4e-23	SMART
CA	3046	3124	2.4e-26	SMART
CA	3148	3229	1.3e-32	SMART
CA	3253	3334	1.3e-29	SMART
CA	3358	3439	4.9e-28	SMART
CA	3463	3544	6.4e-12	SMART
EGF	3793	3828	1.3e-1	SMART
LamG	3852	3989	4.3e-25	SMART
EGF	4019	4053	2.7e-6	SMART
EGF	4058	4091	4.5e-6	SMART
EGF_CA	4093	4129	3.9e-11	SMART
transmembrane domain	4151	4170	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000215388

Predicted Effect

probably benign
Transcript: ENSMUST00000217308
AA Change: V3527G

PolyPhen 2 Score 0.023 (Sensitivity: 0.95; Specificity: 0.81)

Meta Mutation Damage Score

0.0648

Coding Region Coverage

1x: 99.3%
3x: 98.6%
10x: 97.3%
20x: 95.4%

Validation Efficiency

99% (106/107)

MGI Phenotype

PHENOTYPE: Mice homozgyous for a knock-out allele exhibit abnormal amacrine cell differentiation and migration that result in the formation of two additional plexiform layers and thickened retinal ganglion layer. [provided by MGI curators]

Allele List at MGI

All alleles(3) : Gene trapped(3)

Other mutations in this stock

Total: 100 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4930402H24Rik	C	A	2: 130,764,499	K415N	probably benign	Het
4930449A18Rik	T	C	3: 59,846,693		noncoding transcript	Het
Abca9	G	A	11: 110,134,236	L994F	probably damaging	Het
Abl2	A	T	1: 156,629,880	S239C	probably damaging	Het
Acsl5	T	A	19: 55,279,565		probably null	Het
Aff1	C	T	5: 103,783,870	T126I	probably damaging	Het
Amtn	T	C	5: 88,381,626	L107P	probably damaging	Het
Ankrd45	A	G	1: 161,159,112		probably benign	Het
Arl6ip5	G	A	6: 97,210,926	V36I	probably damaging	Het
Ascc3	T	A	10: 50,658,983	D657E	probably damaging	Het
Ascl1	T	A	10: 87,492,946	Q48L	unknown	Het
Asic4	T	A	1: 75,451,319	V163E	probably benign	Het
Atm	A	T	9: 53,459,804	M2245K	probably benign	Het
Barx2	T	G	9: 31,912,989	T35P	probably damaging	Het
BC027072	A	T	17: 71,750,842	S613R	probably damaging	Het
Bdh1	C	T	16: 31,456,657	R235C	probably damaging	Het
C8b	T	A	4: 104,800,349	Y404*	probably null	Het
Car5a	A	G	8: 121,917,242		probably benign	Het
Ccdc13	T	C	9: 121,799,043	I169M	probably benign	Het
Cd163	A	T	6: 124,327,964	D1100V	probably benign	Het
Cntfr	T	C	4: 41,663,322	N162D	probably damaging	Het
Cops3	T	G	11: 59,824,345	D289A	probably damaging	Het
Crbn	A	T	6: 106,795,900	S42R	probably damaging	Het
Cth	T	A	3: 157,894,826	H397L	probably benign	Het
Dact2	A	G	17: 14,195,748	L730P	probably damaging	Het
Dhx37	C	T	5: 125,429,803	G210R	probably benign	Het
Dnah1	T	C	14: 31,316,747	I126V	probably benign	Het
Dnttip2	T	C	3: 122,278,769	I566T	probably damaging	Het
Ehbp1l1	G	T	19: 5,716,248	R412S	possibly damaging	Het
Fam110b	A	C	4: 5,799,104	Q174P	probably benign	Het
Fam149a	A	T	8: 45,348,471	S457T	probably benign	Het
Fat4	A	G	3: 38,891,346	M1463V	probably benign	Het
Gak	T	A	5: 108,592,352	I566F	possibly damaging	Het
Gdf10	T	A	14: 33,932,256	I240N	probably damaging	Het
Gprc6a	T	A	10: 51,626,702	H355L	probably benign	Het
Gxylt1	T	C	15: 93,247,899	K338R	probably damaging	Het
Hexim2	A	T	11: 103,138,269	E49V	probably null	Het
Hfm1	T	C	5: 106,892,772	D709G	possibly damaging	Het
Ighv1-49	T	C	12: 115,055,461	K19R	probably damaging	Het
Il17a	T	A	1: 20,733,646	Y88*	probably null	Het
Iqsec1	A	T	6: 90,845,361		probably benign	Het
Itih2	T	C	2: 10,105,196	D582G	probably benign	Het
Klc3	T	C	7: 19,397,959		probably null	Het
Larp4	T	A	15: 99,986,114	N78K	probably damaging	Het
Larp4b	A	G	13: 9,168,900	D526G	possibly damaging	Het
Lexm	A	T	4: 106,610,493	H315Q	probably benign	Het
Limch1	T	C	5: 66,974,566	V133A	possibly damaging	Het
Lmbr1l	G	A	15: 98,904,791	R426C	probably damaging	Het
Lox	T	A	18: 52,529,103	D76V	probably benign	Het
Lrrc8d	T	A	5: 105,812,552	I276N	probably damaging	Het
Ltbr	G	A	6: 125,312,794	R146W	probably damaging	Het
March10	A	T	11: 105,402,165	Y139N	possibly damaging	Het
Mrc1	T	G	2: 14,266,515	I410S	probably damaging	Het
Mrto4	A	T	4: 139,347,965	C176S	probably damaging	Het
Mtch1	G	T	17: 29,347,590	D66E	probably benign	Het
Nbas	T	G	12: 13,374,811	L1017R	probably damaging	Het
Nim1k	A	G	13: 119,727,529		probably benign	Het
Nlrp6	T	A	7: 140,922,717	Y245*	probably null	Het
Olfr1264	T	A	2: 90,021,665	M134L	probably benign	Het
Olfr192	C	T	16: 59,098,819	V58I	unknown	Het
Olfr224	T	A	11: 58,566,937	H136L	probably benign	Het
Olfr635	A	T	7: 103,979,266	I25F	probably benign	Het
Olfr740	T	G	14: 50,453,727	V225G	probably damaging	Het
Olfr906	A	C	9: 38,488,539	D170A	probably benign	Het
Pcnx	G	T	12: 81,860,406	G12V	probably damaging	Het
Pdzd3	A	G	9: 44,248,355	V448A	possibly damaging	Het
Pkp1	T	A	1: 135,918,918	K32M	probably damaging	Het
Poc5	T	C	13: 96,396,813	W150R	probably damaging	Het
Ppp1r16b	T	A	2: 158,757,333		probably benign	Het
Prune2	T	A	19: 17,020,643	M248K	probably damaging	Het
Rb1	A	T	14: 73,213,140		probably null	Het
Rhod	A	G	19: 4,426,587	C169R	probably benign	Het
Rif1	T	C	2: 52,120,971		probably benign	Het
Rnpc3	G	A	3: 113,624,999	A100V	probably damaging	Het
Rsf1	GCGGC	GCGGCGGCGTCGGC	7: 97,579,931		probably benign	Het
Scnn1a	A	T	6: 125,343,022	D528V	possibly damaging	Het
Sdhaf3	C	A	6: 7,038,855	T59K	probably benign	Het
Sec31a	C	A	5: 100,363,839	A330S	probably damaging	Het
Sgk3	A	G	1: 9,881,872	D241G	probably damaging	Het
Skint6	T	G	4: 113,096,591	I459L	probably benign	Het
Slco1a5	A	T	6: 142,254,392	V222E	probably damaging	Het
Slit3	T	A	11: 35,707,911	N1447K	probably benign	Het
Sorbs2	A	G	8: 45,796,001	H628R	probably damaging	Het
St6galnac2	A	G	11: 116,684,527		probably benign	Het
Tbc1d31	T	C	15: 57,952,871	V667A	probably benign	Het
Tbx20	A	T	9: 24,769,720	Y159N	probably damaging	Het
Tmprss11b	T	A	5: 86,662,233	Q296L	probably benign	Het
Ttc6	T	A	12: 57,674,594		probably null	Het
Ttn	T	A	2: 76,870,899		probably benign	Het
Tubgcp4	T	A	2: 121,194,182	F613I	probably benign	Het
Tubgcp4	T	A	2: 121,188,136	L340H	probably damaging	Het
Urb1	T	C	16: 90,792,762	Y377C	probably damaging	Het
Utp15	G	A	13: 98,260,846		probably null	Het
Vstm2b	A	G	7: 40,901,283		probably null	Het
Vwde	A	T	6: 13,190,628	V488D	probably damaging	Het
Wee1	TCCCC	TCCC	7: 110,124,569		probably null	Het
Zfp276	A	T	8: 123,265,282		probably benign	Het
Zfp318	T	A	17: 46,413,049	S1993T	possibly damaging	Het
Zfp959	T	C	17: 55,897,626	L218P	probably benign	Het
Zxdc	A	G	6: 90,370,560	D301G	probably damaging	Het

Other mutations in Fat3

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00662:Fat3	APN	9	15996427	missense	possibly damaging	0.77
IGL00962:Fat3	APN	9	15915519	missense	probably benign	0.14
IGL00966:Fat3	APN	9	15999094	missense	possibly damaging	0.69
IGL01100:Fat3	APN	9	16375228	missense	probably damaging	1.00
IGL01104:Fat3	APN	9	16375728	missense	possibly damaging	0.92
IGL01104:Fat3	APN	9	15998460	missense	probably damaging	1.00
IGL01121:Fat3	APN	9	15998401	missense	probably benign	0.00
IGL01407:Fat3	APN	9	16378023	missense	probably benign	0.01
IGL01444:Fat3	APN	9	15998848	missense	probably damaging	1.00
IGL01634:Fat3	APN	9	15998358	missense	probably damaging	1.00
IGL01649:Fat3	APN	9	16376719	missense	possibly damaging	0.95
IGL01839:Fat3	APN	9	15997872	missense	probably damaging	1.00
IGL01867:Fat3	APN	9	16377901	missense	probably benign	0.03
IGL01894:Fat3	APN	9	16375849	missense	probably benign
IGL01913:Fat3	APN	9	15998790	missense	probably damaging	0.99
IGL02033:Fat3	APN	9	15915352	missense	possibly damaging	0.50
IGL02035:Fat3	APN	9	16377970	missense	probably benign	0.06
IGL02146:Fat3	APN	9	15999582	missense	probably benign
IGL02147:Fat3	APN	9	15995985	missense	probably damaging	1.00
IGL02161:Fat3	APN	9	15997050	missense	probably benign	0.10
IGL02161:Fat3	APN	9	15997051	nonsense	probably null
IGL02164:Fat3	APN	9	16031424	splice site	probably benign
IGL02269:Fat3	APN	9	15915577	missense	possibly damaging	0.84
IGL02314:Fat3	APN	9	15969838	missense	possibly damaging	0.61
IGL02393:Fat3	APN	9	15988412	nonsense	probably null
IGL02410:Fat3	APN	9	15997845	missense	probably damaging	1.00
IGL02504:Fat3	APN	9	15959798	missense	probably damaging	1.00
IGL02572:Fat3	APN	9	15960506	missense	probably benign
IGL02623:Fat3	APN	9	15997137	missense	probably damaging	1.00
IGL02654:Fat3	APN	9	15996975	missense	possibly damaging	0.84
IGL02749:Fat3	APN	9	16006711	missense	possibly damaging	0.93
IGL02810:Fat3	APN	9	16376850	missense	probably damaging	1.00
IGL02839:Fat3	APN	9	15919170	missense	probably damaging	1.00
IGL02890:Fat3	APN	9	15915340	missense	probably benign	0.03
IGL02892:Fat3	APN	9	16377562	missense	probably damaging	1.00
IGL03090:Fat3	APN	9	16377239	nonsense	probably null
IGL03144:Fat3	APN	9	16375245	missense	probably damaging	1.00
IGL03199:Fat3	APN	9	16377048	missense	possibly damaging	0.83
IGL03365:Fat3	APN	9	15996469	missense	probably damaging	1.00
IGL03392:Fat3	APN	9	16003862	missense	probably benign
IGL03408:Fat3	APN	9	15997957	nonsense	probably null
gagged	UTSW	9	15998271	missense	probably damaging	1.00
hushed	UTSW	9	15959869	missense	possibly damaging	0.72
Muffled	UTSW	9	15937991	critical splice donor site	probably null
muted	UTSW	9	15997477	missense	possibly damaging	0.93
Softened	UTSW	9	16378185	missense	probably benign
BB001:Fat3	UTSW	9	15999297	missense	probably damaging	1.00
BB002:Fat3	UTSW	9	16031360	missense	possibly damaging	0.77
BB011:Fat3	UTSW	9	15999297	missense	probably damaging	1.00
BB012:Fat3	UTSW	9	16031360	missense	possibly damaging	0.77
F6893:Fat3	UTSW	9	16006789	missense	probably damaging	0.99
IGL03050:Fat3	UTSW	9	15996600	missense	probably benign	0.04
PIT4142001:Fat3	UTSW	9	15992118	critical splice donor site	probably null
PIT4283001:Fat3	UTSW	9	16006601	missense	possibly damaging	0.77
PIT4378001:Fat3	UTSW	9	16376808	missense	probably benign	0.05
PIT4434001:Fat3	UTSW	9	15996316	missense	probably benign	0.00
PIT4468001:Fat3	UTSW	9	15996351	missense	probably benign	0.06
R0001:Fat3	UTSW	9	16377873	missense	probably damaging	0.99
R0005:Fat3	UTSW	9	15962866	missense	probably damaging	1.00
R0005:Fat3	UTSW	9	15962866	missense	probably damaging	1.00
R0038:Fat3	UTSW	9	15915010	missense	probably damaging	1.00
R0046:Fat3	UTSW	9	15965979	missense	possibly damaging	0.65
R0089:Fat3	UTSW	9	15938205	missense	probably benign
R0135:Fat3	UTSW	9	16006777	missense	probably damaging	1.00
R0255:Fat3	UTSW	9	15969706	splice site	probably benign
R0349:Fat3	UTSW	9	16031180	missense	probably damaging	1.00
R0361:Fat3	UTSW	9	15998403	missense	possibly damaging	0.77
R0382:Fat3	UTSW	9	15959756	missense	probably damaging	1.00
R0418:Fat3	UTSW	9	16246896	missense	probably damaging	1.00
R0419:Fat3	UTSW	9	15992256	missense	probably damaging	1.00
R0437:Fat3	UTSW	9	15996932	missense	probably damaging	1.00
R0441:Fat3	UTSW	9	15945008	splice site	probably benign
R0480:Fat3	UTSW	9	15997729	missense	probably benign	0.00
R0510:Fat3	UTSW	9	15999685	nonsense	probably null
R0665:Fat3	UTSW	9	15997402	missense	probably benign
R0715:Fat3	UTSW	9	16375123	missense	probably benign
R0727:Fat3	UTSW	9	15996699	missense	probably damaging	1.00
R0882:Fat3	UTSW	9	16031368	missense	possibly damaging	0.84
R0946:Fat3	UTSW	9	15997804	missense	possibly damaging	0.95
R1068:Fat3	UTSW	9	15970034	missense	probably benign
R1081:Fat3	UTSW	9	16375284	missense	possibly damaging	0.62
R1082:Fat3	UTSW	9	16006615	missense	probably damaging	1.00
R1148:Fat3	UTSW	9	15996774	missense	probably damaging	1.00
R1148:Fat3	UTSW	9	15996774	missense	probably damaging	1.00
R1233:Fat3	UTSW	9	15922745	missense	probably benign
R1306:Fat3	UTSW	9	16376679	missense	probably damaging	1.00
R1311:Fat3	UTSW	9	16021410	missense	probably damaging	1.00
R1338:Fat3	UTSW	9	15925091	missense	probably benign	0.00
R1395:Fat3	UTSW	9	16246916	missense	probably benign	0.00
R1466:Fat3	UTSW	9	16375482	missense	probably damaging	0.96
R1466:Fat3	UTSW	9	16375482	missense	probably damaging	0.96
R1510:Fat3	UTSW	9	15960055	missense	probably damaging	1.00
R1528:Fat3	UTSW	9	15925091	missense	probably benign	0.00
R1531:Fat3	UTSW	9	15997465	missense	probably damaging	1.00
R1659:Fat3	UTSW	9	15997183	missense	possibly damaging	0.91
R1697:Fat3	UTSW	9	15944880	missense	probably benign	0.05
R1699:Fat3	UTSW	9	15938398	missense	probably damaging	1.00
R1728:Fat3	UTSW	9	15996315	missense	possibly damaging	0.65
R1729:Fat3	UTSW	9	15996315	missense	possibly damaging	0.65
R1731:Fat3	UTSW	9	15995937	missense	probably benign
R1784:Fat3	UTSW	9	15996315	missense	possibly damaging	0.65
R1789:Fat3	UTSW	9	16376985	missense	probably benign	0.00
R1794:Fat3	UTSW	9	15997136	nonsense	probably null
R1794:Fat3	UTSW	9	15997138	missense	probably benign	0.15
R1830:Fat3	UTSW	9	15915340	missense	probably benign	0.03
R1835:Fat3	UTSW	9	15998088	missense	probably damaging	1.00
R1887:Fat3	UTSW	9	15967061	missense	probably damaging	1.00
R1898:Fat3	UTSW	9	15960130	missense	probably damaging	1.00
R1909:Fat3	UTSW	9	15998115	missense	probably benign
R1912:Fat3	UTSW	9	15969988	missense	probably damaging	1.00
R1917:Fat3	UTSW	9	15997057	missense	possibly damaging	0.55
R1967:Fat3	UTSW	9	15968295	missense	probably benign	0.00
R2070:Fat3	UTSW	9	15999370	missense	probably benign	0.21
R2100:Fat3	UTSW	9	16377430	missense	possibly damaging	0.73
R2104:Fat3	UTSW	9	15998517	missense	possibly damaging	0.77
R2113:Fat3	UTSW	9	15999786	missense	probably damaging	1.00
R2132:Fat3	UTSW	9	16246719	critical splice donor site	probably null
R2136:Fat3	UTSW	9	16377051	missense	probably benign	0.01
R2146:Fat3	UTSW	9	15990512	missense	probably benign	0.01
R2233:Fat3	UTSW	9	15998271	missense	probably damaging	1.00
R2234:Fat3	UTSW	9	15998271	missense	probably damaging	1.00
R2273:Fat3	UTSW	9	15915262	missense	probably benign
R2285:Fat3	UTSW	9	16376173	missense	probably damaging	1.00
R2363:Fat3	UTSW	9	15998271	missense	probably damaging	1.00
R2365:Fat3	UTSW	9	15998271	missense	probably damaging	1.00
R2367:Fat3	UTSW	9	15998271	missense	probably damaging	1.00
R2403:Fat3	UTSW	9	15969871	missense	probably damaging	1.00
R2447:Fat3	UTSW	9	15998271	missense	probably damaging	1.00
R2496:Fat3	UTSW	9	15966103	missense	probably benign	0.01
R2509:Fat3	UTSW	9	15925014	missense	possibly damaging	0.82
R2932:Fat3	UTSW	9	16375944	missense	probably damaging	1.00
R2986:Fat3	UTSW	9	15992128	missense	probably damaging	1.00
R3054:Fat3	UTSW	9	15960496	missense	probably benign
R3056:Fat3	UTSW	9	15960496	missense	probably benign
R3729:Fat3	UTSW	9	16247041	splice site	probably benign
R3745:Fat3	UTSW	9	15998271	missense	probably damaging	1.00
R3806:Fat3	UTSW	9	15998271	missense	probably damaging	1.00
R3859:Fat3	UTSW	9	15997228	nonsense	probably null
R3862:Fat3	UTSW	9	15998271	missense	probably damaging	1.00
R3890:Fat3	UTSW	9	15998271	missense	probably damaging	1.00
R3892:Fat3	UTSW	9	15998271	missense	probably damaging	1.00
R3950:Fat3	UTSW	9	15998271	missense	probably damaging	1.00
R3972:Fat3	UTSW	9	15998271	missense	probably damaging	1.00
R4004:Fat3	UTSW	9	15998271	missense	probably damaging	1.00
R4005:Fat3	UTSW	9	15998271	missense	probably damaging	1.00
R4086:Fat3	UTSW	9	15998271	missense	probably damaging	1.00
R4111:Fat3	UTSW	9	15998271	missense	probably damaging	1.00
R4113:Fat3	UTSW	9	15998271	missense	probably damaging	1.00
R4227:Fat3	UTSW	9	16377693	missense	probably damaging	1.00
R4352:Fat3	UTSW	9	16246778	missense	possibly damaging	0.55
R4394:Fat3	UTSW	9	15922792	missense	probably benign	0.11
R4403:Fat3	UTSW	9	15944873	missense	probably damaging	1.00
R4433:Fat3	UTSW	9	16031152	missense	probably damaging	0.99
R4453:Fat3	UTSW	9	15998271	missense	probably damaging	1.00
R4479:Fat3	UTSW	9	15998271	missense	probably damaging	1.00
R4480:Fat3	UTSW	9	15998271	missense	probably damaging	1.00
R4521:Fat3	UTSW	9	15922942	missense	probably null	0.71
R4620:Fat3	UTSW	9	15996894	missense	probably damaging	1.00
R4700:Fat3	UTSW	9	16031173	missense	probably damaging	1.00
R4721:Fat3	UTSW	9	16029966	missense	probably damaging	1.00
R4790:Fat3	UTSW	9	15998484	missense	probably damaging	1.00
R4796:Fat3	UTSW	9	15999732	missense	probably benign	0.17
R4823:Fat3	UTSW	9	15996507	missense	probably benign
R4836:Fat3	UTSW	9	16377723	missense	probably damaging	1.00
R4842:Fat3	UTSW	9	15997587	missense	probably damaging	1.00
R4849:Fat3	UTSW	9	16377948	missense	probably benign	0.03
R4856:Fat3	UTSW	9	16021330	missense	probably benign
R4869:Fat3	UTSW	9	16377477	missense	probably damaging	0.98
R4886:Fat3	UTSW	9	16021330	missense	probably benign
R4899:Fat3	UTSW	9	15969799	missense	probably damaging	1.00
R4941:Fat3	UTSW	9	16375152	missense	probably damaging	1.00
R4986:Fat3	UTSW	9	15998340	missense	probably damaging	1.00
R5058:Fat3	UTSW	9	15996858	missense	probably damaging	1.00
R5079:Fat3	UTSW	9	15999127	missense	probably benign	0.01
R5080:Fat3	UTSW	9	15999338	missense	probably benign	0.35
R5174:Fat3	UTSW	9	15999570	missense	probably damaging	1.00
R5183:Fat3	UTSW	9	15960313	missense	probably damaging	0.99
R5203:Fat3	UTSW	9	16378142	missense	possibly damaging	0.79
R5216:Fat3	UTSW	9	16377537	missense	probably damaging	1.00
R5230:Fat3	UTSW	9	15990560	missense	possibly damaging	0.51
R5318:Fat3	UTSW	9	16376629	missense	probably damaging	1.00
R5377:Fat3	UTSW	9	16376443	missense	probably benign	0.05
R5385:Fat3	UTSW	9	15922675	missense	possibly damaging	0.82
R5437:Fat3	UTSW	9	16085308	missense	probably damaging	1.00
R5453:Fat3	UTSW	9	15996864	missense	probably damaging	1.00
R5460:Fat3	UTSW	9	15919167	missense	probably damaging	1.00
R5516:Fat3	UTSW	9	15998709	missense	probably damaging	1.00
R5568:Fat3	UTSW	9	16376923	nonsense	probably null
R5628:Fat3	UTSW	9	15966096	missense	probably damaging	1.00
R5835:Fat3	UTSW	9	16375833	missense	probably damaging	1.00
R5845:Fat3	UTSW	9	16377210	missense	probably damaging	1.00
R5898:Fat3	UTSW	9	15938461	missense	probably benign	0.15
R5941:Fat3	UTSW	9	15999501	missense	probably benign	0.07
R5974:Fat3	UTSW	9	16006528	critical splice donor site	probably null
R5986:Fat3	UTSW	9	15998317	missense	probably benign	0.22
R6015:Fat3	UTSW	9	16376050	missense	possibly damaging	0.55
R6031:Fat3	UTSW	9	15988492	missense	probably benign	0.02
R6031:Fat3	UTSW	9	15988492	missense	probably benign	0.02
R6042:Fat3	UTSW	9	16377817	missense	probably benign	0.12
R6051:Fat3	UTSW	9	16375455	missense	possibly damaging	0.83
R6052:Fat3	UTSW	9	15922679	missense	probably null
R6119:Fat3	UTSW	9	16376568	missense	possibly damaging	0.82
R6161:Fat3	UTSW	9	16377522	missense	probably damaging	1.00
R6254:Fat3	UTSW	9	15996145	missense	probably benign	0.19
R6318:Fat3	UTSW	9	15916984	intron	probably benign
R6347:Fat3	UTSW	9	15998372	missense	probably damaging	1.00
R6348:Fat3	UTSW	9	15937991	critical splice donor site	probably null
R6351:Fat3	UTSW	9	15938398	missense	probably damaging	1.00
R6450:Fat3	UTSW	9	15999170	missense	possibly damaging	0.51
R6460:Fat3	UTSW	9	15967000	missense	probably damaging	1.00
R6524:Fat3	UTSW	9	15992256	missense	probably damaging	1.00
R6533:Fat3	UTSW	9	15998899	missense	probably benign	0.02
R6565:Fat3	UTSW	9	15915327	missense	probably benign
R6576:Fat3	UTSW	9	16377210	missense	probably damaging	1.00
R6649:Fat3	UTSW	9	16376742	missense	probably damaging	1.00
R6716:Fat3	UTSW	9	15919269	missense	probably benign
R6719:Fat3	UTSW	9	15996144	missense	probably benign
R6753:Fat3	UTSW	9	15915061	missense	possibly damaging	0.82
R6754:Fat3	UTSW	9	15915061	missense	possibly damaging	0.82
R6755:Fat3	UTSW	9	15915061	missense	possibly damaging	0.82
R6792:Fat3	UTSW	9	16375644	missense	probably damaging	1.00
R6802:Fat3	UTSW	9	15915061	missense	possibly damaging	0.82
R6803:Fat3	UTSW	9	15996787	missense	probably damaging	0.99
R6831:Fat3	UTSW	9	15915061	missense	possibly damaging	0.82
R6831:Fat3	UTSW	9	16376551	missense	probably damaging	0.98
R6833:Fat3	UTSW	9	15915061	missense	possibly damaging	0.82
R6877:Fat3	UTSW	9	15999268	missense	probably benign
R6894:Fat3	UTSW	9	15997776	missense	probably damaging	1.00
R6915:Fat3	UTSW	9	16377748	missense	probably benign	0.37
R6931:Fat3	UTSW	9	15959942	missense	possibly damaging	0.89
R6934:Fat3	UTSW	9	16376956	missense	probably damaging	0.98
R6940:Fat3	UTSW	9	15916800	splice site	probably null
R6959:Fat3	UTSW	9	15996885	missense	possibly damaging	0.91
R6969:Fat3	UTSW	9	16029916	missense	probably benign	0.29
R6986:Fat3	UTSW	9	16021335	missense	probably damaging	1.00
R6993:Fat3	UTSW	9	15919221	missense	probably damaging	1.00
R7039:Fat3	UTSW	9	16376265	missense	probably damaging	1.00
R7051:Fat3	UTSW	9	16377827	missense	probably damaging	1.00
R7089:Fat3	UTSW	9	15996918	missense	probably benign	0.01
R7136:Fat3	UTSW	9	16378185	missense	probably benign
R7137:Fat3	UTSW	9	15997148	missense	probably damaging	1.00
R7154:Fat3	UTSW	9	15996864	missense	probably damaging	1.00
R7170:Fat3	UTSW	9	16006574	missense	probably damaging	0.99
R7183:Fat3	UTSW	9	15922837	missense	possibly damaging	0.81
R7237:Fat3	UTSW	9	16377214	missense	probably damaging	1.00
R7288:Fat3	UTSW	9	15998592	missense	probably damaging	1.00
R7293:Fat3	UTSW	9	15915040	missense
R7293:Fat3	UTSW	9	15915296	missense
R7381:Fat3	UTSW	9	16246987	missense	probably damaging	1.00
R7438:Fat3	UTSW	9	15988482	missense	probably benign
R7537:Fat3	UTSW	9	15938319	missense	probably damaging	1.00
R7560:Fat3	UTSW	9	15996842	missense	probably damaging	1.00
R7585:Fat3	UTSW	9	15998262	missense	probably benign	0.03
R7623:Fat3	UTSW	9	15988324	missense	probably damaging	1.00
R7624:Fat3	UTSW	9	15959869	missense	possibly damaging	0.72
R7684:Fat3	UTSW	9	15988268	critical splice donor site	probably null
R7690:Fat3	UTSW	9	15998181	missense	probably damaging	1.00
R7804:Fat3	UTSW	9	15990592	missense	probably benign	0.01
R7809:Fat3	UTSW	9	16006628	missense	probably damaging	1.00
R7924:Fat3	UTSW	9	15999297	missense	probably damaging	1.00
R7925:Fat3	UTSW	9	16031360	missense	possibly damaging	0.77
R7954:Fat3	UTSW	9	15998412	missense	probably damaging	1.00
R8021:Fat3	UTSW	9	15999109	missense	probably damaging	0.99
R8118:Fat3	UTSW	9	15960104	missense	probably benign
R8141:Fat3	UTSW	9	15997066	missense	possibly damaging	0.79
R8163:Fat3	UTSW	9	15959759	missense	probably damaging	1.00
R8170:Fat3	UTSW	9	15947496	missense	probably damaging	0.97
R8201:Fat3	UTSW	9	15997477	missense	possibly damaging	0.93
R8258:Fat3	UTSW	9	15990591	missense	possibly damaging	0.79
R8259:Fat3	UTSW	9	15990591	missense	possibly damaging	0.79
R8274:Fat3	UTSW	9	16377490	nonsense	probably null
R8275:Fat3	UTSW	9	16246750	missense	probably damaging	1.00
R8345:Fat3	UTSW	9	15999274	missense	probably benign	0.08
R8350:Fat3	UTSW	9	15915139	missense
R8405:Fat3	UTSW	9	15995871	missense	probably damaging	1.00
R8421:Fat3	UTSW	9	15998184	missense	probably damaging	1.00
R8450:Fat3	UTSW	9	15915139	missense
R8472:Fat3	UTSW	9	16375267	missense	possibly damaging	0.90
R8482:Fat3	UTSW	9	16246967	missense	probably benign	0.02
R8680:Fat3	UTSW	9	15997407	missense	probably damaging	0.99
R8690:Fat3	UTSW	9	15967101	missense	probably benign	0.45
R8748:Fat3	UTSW	9	15922865	missense	possibly damaging	0.70
R8756:Fat3	UTSW	9	16376589	missense	probably damaging	1.00
R8834:Fat3	UTSW	9	16031197	missense	probably damaging	1.00
R8848:Fat3	UTSW	9	15967102	missense	probably damaging	1.00
R8884:Fat3	UTSW	9	16029984	missense	probably damaging	1.00
R8898:Fat3	UTSW	9	15947526	missense	probably benign	0.04
R8930:Fat3	UTSW	9	15999523	missense	probably benign	0.06
R8932:Fat3	UTSW	9	15999523	missense	probably benign	0.06
R8954:Fat3	UTSW	9	16376568	missense	probably benign	0.00
R8995:Fat3	UTSW	9	16375602	missense	probably damaging	1.00
R9000:Fat3	UTSW	9	15960520	missense	possibly damaging	0.82
R9000:Fat3	UTSW	9	16006799	missense	probably benign	0.12
R9060:Fat3	UTSW	9	15999486	missense	possibly damaging	0.80
R9116:Fat3	UTSW	9	15998125	missense	probably benign	0.34
R9136:Fat3	UTSW	9	15922442	missense
R9193:Fat3	UTSW	9	15998952	missense	probably benign
R9235:Fat3	UTSW	9	15922378	missense	probably null
R9257:Fat3	UTSW	9	15996567	missense	probably benign
R9297:Fat3	UTSW	9	15997700	missense	probably damaging	1.00
R9307:Fat3	UTSW	9	16021423	missense	probably damaging	1.00
R9412:Fat3	UTSW	9	15997407	missense	probably damaging	0.99
R9427:Fat3	UTSW	9	16377395	nonsense	probably null
R9430:Fat3	UTSW	9	16376085	missense	probably damaging	1.00
R9480:Fat3	UTSW	9	16031407	missense	probably damaging	1.00
R9497:Fat3	UTSW	9	15992208	missense	probably damaging	0.99
R9547:Fat3	UTSW	9	15999846	missense	possibly damaging	0.86
R9569:Fat3	UTSW	9	15919199	missense
R9591:Fat3	UTSW	9	16377040	missense	probably benign	0.01
R9615:Fat3	UTSW	9	16378047	missense	probably benign	0.00
R9649:Fat3	UTSW	9	15996758	missense	possibly damaging	0.57
R9671:Fat3	UTSW	9	16375575	missense	possibly damaging	0.93
R9750:Fat3	UTSW	9	16003861	missense	probably benign	0.00
R9777:Fat3	UTSW	9	15915241	missense	probably benign
RF006:Fat3	UTSW	9	15998617	missense	probably benign	0.36
X0021:Fat3	UTSW	9	16029931	missense	probably null	0.66
X0026:Fat3	UTSW	9	15996333	missense	probably benign
X0064:Fat3	UTSW	9	15919277	missense	probably benign
Z1176:Fat3	UTSW	9	15947526	missense	probably damaging	0.98
Z1176:Fat3	UTSW	9	16375429	missense	probably damaging	1.00
Z1176:Fat3	UTSW	9	16375617	missense	probably benign
Z1177:Fat3	UTSW	9	15923026	missense	possibly damaging	0.81
Z1177:Fat3	UTSW	9	15947538	missense	probably damaging	1.00
Z1177:Fat3	UTSW	9	15965991	missense	possibly damaging	0.68
Z1177:Fat3	UTSW	9	15969835	missense	probably damaging	0.99

Predicted Primers

PCR Primer
(F):5'- TCTGATTTCAGGGCGAACGTG -3'
(R):5'- TACAGTACCCAGAGAATGACTGAAG -3'

Sequencing Primer
(F):5'- GTGAGCACGTCATACATGTCCTG -3'
(R):5'- TGACTGAAGGTGATAAACAACTCCTC -3'

Posted On

2016-09-01