Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01139:Dmxl2'

51996

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Dmxl2

Ensembl Gene

ENSMUSG00000041268

Gene Name

Dmx-like 2

Synonyms

E130119P06Rik, 6430411K14Rik

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

IGL01139

Quality Score

Status

Chromosome

Chromosomal Location

54272442-54408910 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

G to A at 54366248 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Proline to Serine at position 274 (P274S)

Ref Sequence

ENSEMBL: ENSMUSP00000113705 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000118163] [ENSMUST00000118600] [ENSMUST00000127880]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000118163
AA Change: P274S

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000113705
Gene: ENSMUSG00000041268
AA Change: P274S

Domain	Start	End	E-Value	Type
WD40	43	84	4.58e1	SMART
WD40	100	136	2.28e2	SMART
WD40	159	198	2.57e-2	SMART
WD40	221	269	1.03e-1	SMART
low complexity region	420	440	N/A	INTRINSIC
WD40	741	793	1.42e2	SMART
low complexity region	861	875	N/A	INTRINSIC
low complexity region	945	961	N/A	INTRINSIC
WD40	985	1029	1.15e1	SMART
WD40	1236	1273	2.84e2	SMART
Pfam:Rav1p_C	1430	1903	1.5e-71	PFAM
low complexity region	1978	1993	N/A	INTRINSIC
coiled coil region	2118	2146	N/A	INTRINSIC
low complexity region	2189	2204	N/A	INTRINSIC
low complexity region	2251	2266	N/A	INTRINSIC
low complexity region	2472	2490	N/A	INTRINSIC
low complexity region	2635	2649	N/A	INTRINSIC
low complexity region	2744	2766	N/A	INTRINSIC
WD40	2774	2809	5.73e0	SMART
WD40	2813	2852	8.88e0	SMART
WD40	2859	2901	2.67e-1	SMART
WD40	2907	2946	2.57e-2	SMART
WD40	2949	2988	3.61e-6	SMART
WD40	3001	3039	8.25e0	SMART

Predicted Effect

possibly damaging
Transcript: ENSMUST00000118600
AA Change: P274S

PolyPhen 2 Score 0.930 (Sensitivity: 0.81; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000113693
Gene: ENSMUSG00000041268
AA Change: P274S

Domain	Start	End	E-Value	Type
WD40	43	84	4.58e1	SMART
WD40	100	136	2.28e2	SMART
WD40	159	198	2.57e-2	SMART
WD40	221	269	1.03e-1	SMART
low complexity region	420	440	N/A	INTRINSIC
WD40	741	793	1.42e2	SMART
low complexity region	861	875	N/A	INTRINSIC
low complexity region	945	961	N/A	INTRINSIC
WD40	985	1029	1.15e1	SMART
WD40	1236	1273	2.84e2	SMART
low complexity region	1426	1436	N/A	INTRINSIC
Pfam:Rav1p_C	1447	1903	4.2e-68	PFAM
low complexity region	1978	1993	N/A	INTRINSIC
coiled coil region	2118	2146	N/A	INTRINSIC
low complexity region	2189	2204	N/A	INTRINSIC
low complexity region	2251	2266	N/A	INTRINSIC
low complexity region	2471	2489	N/A	INTRINSIC
low complexity region	2722	2744	N/A	INTRINSIC
WD40	2752	2787	5.73e0	SMART
WD40	2791	2830	8.88e0	SMART
WD40	2837	2879	2.67e-1	SMART
WD40	2885	2924	2.57e-2	SMART
WD40	2927	2966	3.61e-6	SMART
WD40	2979	3017	8.25e0	SMART

Predicted Effect

possibly damaging
Transcript: ENSMUST00000127880
AA Change: P100S

PolyPhen 2 Score 0.930 (Sensitivity: 0.81; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000122293
Gene: ENSMUSG00000041268
AA Change: P100S

Domain	Start	End	E-Value	Type
Pfam:WD40	1	24	7.9e-4	PFAM
WD40	47	95	1.03e-1	SMART
low complexity region	246	266	N/A	INTRINSIC
WD40	567	619	1.42e2	SMART
low complexity region	687	701	N/A	INTRINSIC
low complexity region	771	787	N/A	INTRINSIC
WD40	811	855	1.15e1	SMART
WD40	1062	1099	2.84e2	SMART
low complexity region	1252	1262	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000144736

Coding Region Coverage

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein with 12 WD domains. Proteins with WD domains are involved in many functions including participation in signal transduction pathways. Participation of the encoded protein in regulation of the Notch signaling pathway has been demonstrated in vitro using several human cell lines (PMID:20810660). A gene encoding a similar protein is located on chromosome 5. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit complete prenatal lethality. [provided by MGI curators]

Allele List at MGI

All alleles(4) : Targeted(2) Gene trapped(2)

Other mutations in this stock

Total: 47 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aadacl4fm5	A	T	4: 144,504,259 (GRCm39)	Y297*	probably null	Het
Actr3	A	T	1: 125,333,622 (GRCm39)	I215N	probably damaging	Het
Ambn	C	T	5: 88,612,376 (GRCm39)		probably benign	Het
Arhgef1	T	A	7: 24,625,376 (GRCm39)		probably benign	Het
Arid1a	A	C	4: 133,421,308 (GRCm39)	S832R	unknown	Het
Clca4a	A	T	3: 144,672,030 (GRCm39)	I304N	probably damaging	Het
Eif4enif1	T	A	11: 3,171,143 (GRCm39)	D211E	probably damaging	Het
Eri2	A	G	7: 119,385,960 (GRCm39)		probably null	Het
Fhod3	C	T	18: 25,199,401 (GRCm39)	P691S	probably benign	Het
Flnb	A	G	14: 7,945,989 (GRCm38)	S2465G	probably damaging	Het
Ftsj1	G	A	X: 8,112,831 (GRCm39)	R171C	probably damaging	Het
Glb1l3	G	A	9: 26,729,523 (GRCm39)	T648I	probably benign	Het
Gm4222	T	A	2: 89,978,889 (GRCm39)		probably benign	Het
Gm5475	G	A	15: 100,322,096 (GRCm39)		probably benign	Het
Jaml	C	A	9: 45,012,317 (GRCm39)	T268N	possibly damaging	Het
Kank3	G	A	17: 34,036,375 (GRCm39)	G81E	probably damaging	Het
Lrba	A	G	3: 86,549,969 (GRCm39)	T217A	possibly damaging	Het
Ltn1	A	G	16: 87,212,897 (GRCm39)	S555P	probably benign	Het
Map3k15	T	A	X: 158,855,875 (GRCm39)	M350K	probably damaging	Het
Mipol1	C	A	12: 57,352,821 (GRCm39)	Y53*	probably null	Het
Mn1	A	G	5: 111,569,315 (GRCm39)	D1095G	probably damaging	Het
Myh14	T	C	7: 44,255,716 (GRCm39)		probably benign	Het
Nrn1	A	G	13: 36,914,190 (GRCm39)	C31R	probably damaging	Het
Nup210	A	T	6: 91,007,079 (GRCm39)	L579H	possibly damaging	Het
Nxf2	T	C	X: 133,851,145 (GRCm39)	I578V	probably benign	Het
Obscn	G	A	11: 58,969,178 (GRCm39)	A172V	probably damaging	Het
Or10h1b	T	A	17: 33,395,756 (GRCm39)	Y123N	probably damaging	Het
Or9g4	T	G	2: 85,504,841 (GRCm39)	Y218S	probably damaging	Het
Phtf1	A	G	3: 103,912,918 (GRCm39)	D748G	probably damaging	Het
Psd3	A	T	8: 68,361,187 (GRCm39)	Y863N	probably damaging	Het
Psmc6	C	T	14: 45,581,167 (GRCm39)	T321I	probably benign	Het
Rassf6	T	C	5: 90,756,825 (GRCm39)	*31W	probably null	Het
Rictor	A	C	15: 6,807,749 (GRCm39)	K791Q	probably damaging	Het
Slc12a9	C	T	5: 137,321,104 (GRCm39)	M470I	probably damaging	Het
Tex28	A	T	X: 73,194,830 (GRCm39)	M367K	possibly damaging	Het
Thnsl2	A	T	6: 71,115,718 (GRCm39)	V163D	probably damaging	Het
Tmco3	G	A	8: 13,369,887 (GRCm39)	R633Q	possibly damaging	Het
Trf	A	T	9: 103,100,803 (GRCm39)	V224D	probably damaging	Het
Ttc8	C	T	12: 98,930,804 (GRCm39)	Q273*	probably null	Het
Usp9x	A	G	X: 12,970,815 (GRCm39)		probably benign	Het
Vmn2r117	A	G	17: 23,696,778 (GRCm39)	W210R	probably damaging	Het
Vmn2r5	A	G	3: 64,398,826 (GRCm39)	S718P	probably benign	Het
Vps13a	T	C	19: 16,617,989 (GRCm39)	D2932G	probably damaging	Het
Whamm	T	C	7: 81,245,662 (GRCm39)	L706P	probably damaging	Het
Yeats2	G	A	16: 20,033,143 (GRCm39)	V45I	probably damaging	Het
Yipf3	G	A	17: 46,561,383 (GRCm39)		probably null	Het
Zeb1	T	C	18: 5,705,061 (GRCm39)	V26A	possibly damaging	Het

Other mutations in Dmxl2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00088:Dmxl2	APN	9	54,308,988 (GRCm39)	missense	probably benign
IGL00226:Dmxl2	APN	9	54,323,277 (GRCm39)	missense	probably damaging	1.00
IGL00419:Dmxl2	APN	9	54,313,951 (GRCm39)	missense	probably damaging	0.96
IGL00551:Dmxl2	APN	9	54,358,122 (GRCm39)	missense	probably damaging	1.00
IGL00765:Dmxl2	APN	9	54,322,706 (GRCm39)	unclassified	probably benign
IGL00852:Dmxl2	APN	9	54,330,597 (GRCm39)	nonsense	probably null
IGL00857:Dmxl2	APN	9	54,283,604 (GRCm39)	missense	probably benign	0.32
IGL00952:Dmxl2	APN	9	54,324,166 (GRCm39)	missense	probably damaging	0.99
IGL01346:Dmxl2	APN	9	54,322,759 (GRCm39)	missense	probably damaging	1.00
IGL01538:Dmxl2	APN	9	54,352,660 (GRCm39)	splice site	probably benign
IGL01645:Dmxl2	APN	9	54,286,017 (GRCm39)	missense	possibly damaging	0.93
IGL02096:Dmxl2	APN	9	54,308,349 (GRCm39)	missense	possibly damaging	0.89
IGL02104:Dmxl2	APN	9	54,311,299 (GRCm39)	nonsense	probably null
IGL02145:Dmxl2	APN	9	54,281,981 (GRCm39)	missense	probably benign	0.29
IGL02210:Dmxl2	APN	9	54,311,333 (GRCm39)	missense	probably damaging	1.00
IGL02238:Dmxl2	APN	9	54,352,717 (GRCm39)	missense	probably damaging	1.00
IGL02255:Dmxl2	APN	9	54,301,052 (GRCm39)	missense	probably benign	0.06
IGL02364:Dmxl2	APN	9	54,301,127 (GRCm39)	missense	probably benign	0.02
IGL02423:Dmxl2	APN	9	54,301,032 (GRCm39)	missense	possibly damaging	0.89
IGL02440:Dmxl2	APN	9	54,313,899 (GRCm39)	missense	probably damaging	0.98
IGL02546:Dmxl2	APN	9	54,273,698 (GRCm39)	utr 3 prime	probably benign
IGL02668:Dmxl2	APN	9	54,324,229 (GRCm39)	missense	probably damaging	1.00
IGL03229:Dmxl2	APN	9	54,311,456 (GRCm39)	missense	probably damaging	1.00
IGL03244:Dmxl2	APN	9	54,323,655 (GRCm39)	missense	probably damaging	1.00
IGL03277:Dmxl2	APN	9	54,311,504 (GRCm39)	missense	probably damaging	1.00
IGL03399:Dmxl2	APN	9	54,353,956 (GRCm39)	missense	probably damaging	1.00
BB003:Dmxl2	UTSW	9	54,335,326 (GRCm39)	missense	probably benign	0.01
BB013:Dmxl2	UTSW	9	54,335,326 (GRCm39)	missense	probably benign	0.01
I2288:Dmxl2	UTSW	9	54,309,077 (GRCm39)	missense	probably damaging	1.00
P0014:Dmxl2	UTSW	9	54,309,048 (GRCm39)	missense	probably damaging	1.00
R0411:Dmxl2	UTSW	9	54,286,223 (GRCm39)	missense	probably damaging	1.00
R0422:Dmxl2	UTSW	9	54,307,224 (GRCm39)	critical splice donor site	probably null
R0432:Dmxl2	UTSW	9	54,324,235 (GRCm39)	missense	probably benign	0.01
R0436:Dmxl2	UTSW	9	54,291,034 (GRCm39)	missense	probably damaging	1.00
R0538:Dmxl2	UTSW	9	54,301,120 (GRCm39)	missense	probably benign	0.06
R0603:Dmxl2	UTSW	9	54,313,190 (GRCm39)	missense	possibly damaging	0.95
R0605:Dmxl2	UTSW	9	54,327,229 (GRCm39)	missense	probably benign	0.01
R0625:Dmxl2	UTSW	9	54,289,986 (GRCm39)	missense	probably benign
R0626:Dmxl2	UTSW	9	54,323,838 (GRCm39)	missense	probably damaging	1.00
R0736:Dmxl2	UTSW	9	54,286,101 (GRCm39)	missense	probably damaging	0.99
R0847:Dmxl2	UTSW	9	54,313,112 (GRCm39)	missense	probably damaging	1.00
R0855:Dmxl2	UTSW	9	54,273,724 (GRCm39)	missense	probably benign	0.03
R0962:Dmxl2	UTSW	9	54,353,696 (GRCm39)	missense	probably damaging	0.99
R1015:Dmxl2	UTSW	9	54,275,049 (GRCm39)	missense	probably benign	0.32
R1084:Dmxl2	UTSW	9	54,323,717 (GRCm39)	missense	probably damaging	1.00
R1328:Dmxl2	UTSW	9	54,303,533 (GRCm39)	missense	probably benign	0.12
R1401:Dmxl2	UTSW	9	54,322,712 (GRCm39)	critical splice donor site	probably null
R1503:Dmxl2	UTSW	9	54,354,272 (GRCm39)	nonsense	probably null
R1609:Dmxl2	UTSW	9	54,316,547 (GRCm39)	missense	possibly damaging	0.90
R1613:Dmxl2	UTSW	9	54,289,311 (GRCm39)	missense	probably benign
R1660:Dmxl2	UTSW	9	54,358,314 (GRCm39)	missense	possibly damaging	0.68
R1712:Dmxl2	UTSW	9	54,308,769 (GRCm39)	missense	probably benign	0.00
R1772:Dmxl2	UTSW	9	54,330,508 (GRCm39)	splice site	probably benign
R1832:Dmxl2	UTSW	9	54,368,233 (GRCm39)	missense	probably damaging	0.97
R1922:Dmxl2	UTSW	9	54,308,807 (GRCm39)	missense	probably benign
R2104:Dmxl2	UTSW	9	54,322,848 (GRCm39)	missense	probably damaging	1.00
R2109:Dmxl2	UTSW	9	54,301,097 (GRCm39)	missense	probably benign	0.06
R2145:Dmxl2	UTSW	9	54,323,194 (GRCm39)	missense	probably damaging	1.00
R2199:Dmxl2	UTSW	9	54,283,527 (GRCm39)	missense	probably benign	0.35
R2352:Dmxl2	UTSW	9	54,301,146 (GRCm39)	missense	probably damaging	1.00
R2516:Dmxl2	UTSW	9	54,307,378 (GRCm39)	missense	probably damaging	1.00
R2981:Dmxl2	UTSW	9	54,300,986 (GRCm39)	missense	probably damaging	1.00
R3430:Dmxl2	UTSW	9	54,384,745 (GRCm39)	missense	possibly damaging	0.94
R3625:Dmxl2	UTSW	9	54,300,927 (GRCm39)	missense	probably benign	0.23
R3725:Dmxl2	UTSW	9	54,301,053 (GRCm39)	missense	probably damaging	1.00
R3787:Dmxl2	UTSW	9	54,277,162 (GRCm39)	missense	probably damaging	1.00
R4002:Dmxl2	UTSW	9	54,381,116 (GRCm39)	splice site	probably benign
R4004:Dmxl2	UTSW	9	54,353,674 (GRCm39)	missense	probably benign	0.04
R4005:Dmxl2	UTSW	9	54,353,674 (GRCm39)	missense	probably benign	0.04
R4012:Dmxl2	UTSW	9	54,286,297 (GRCm39)	splice site	probably null
R4014:Dmxl2	UTSW	9	54,285,993 (GRCm39)	splice site	probably null
R4115:Dmxl2	UTSW	9	54,354,272 (GRCm39)	nonsense	probably null
R4232:Dmxl2	UTSW	9	54,327,193 (GRCm39)	missense	possibly damaging	0.89
R4388:Dmxl2	UTSW	9	54,303,551 (GRCm39)	missense	probably damaging	1.00
R4513:Dmxl2	UTSW	9	54,327,168 (GRCm39)	missense	probably null	0.17
R4552:Dmxl2	UTSW	9	54,359,047 (GRCm39)	missense	probably damaging	1.00
R4609:Dmxl2	UTSW	9	54,353,796 (GRCm39)	missense	probably damaging	1.00
R4625:Dmxl2	UTSW	9	54,311,404 (GRCm39)	missense	possibly damaging	0.55
R4694:Dmxl2	UTSW	9	54,354,189 (GRCm39)	missense	probably benign	0.04
R4711:Dmxl2	UTSW	9	54,358,208 (GRCm39)	missense	probably benign	0.37
R4715:Dmxl2	UTSW	9	54,353,689 (GRCm39)	splice site	probably null
R4746:Dmxl2	UTSW	9	54,359,080 (GRCm39)	missense	probably benign	0.04
R4789:Dmxl2	UTSW	9	54,287,099 (GRCm39)	missense	probably benign	0.30
R4825:Dmxl2	UTSW	9	54,311,325 (GRCm39)	missense	probably benign	0.01
R4911:Dmxl2	UTSW	9	54,318,937 (GRCm39)	missense	probably damaging	1.00
R4995:Dmxl2	UTSW	9	54,408,725 (GRCm39)	utr 5 prime	probably benign
R5026:Dmxl2	UTSW	9	54,323,960 (GRCm39)	missense	probably damaging	1.00
R5118:Dmxl2	UTSW	9	54,368,271 (GRCm39)	missense	probably damaging	1.00
R5174:Dmxl2	UTSW	9	54,352,768 (GRCm39)	splice site	probably null
R5288:Dmxl2	UTSW	9	54,286,041 (GRCm39)	missense	probably benign
R5373:Dmxl2	UTSW	9	54,276,473 (GRCm39)	intron	probably benign
R5374:Dmxl2	UTSW	9	54,276,473 (GRCm39)	intron	probably benign
R5385:Dmxl2	UTSW	9	54,286,041 (GRCm39)	missense	probably benign
R5386:Dmxl2	UTSW	9	54,286,041 (GRCm39)	missense	probably benign
R5418:Dmxl2	UTSW	9	54,281,935 (GRCm39)	critical splice donor site	probably null
R5540:Dmxl2	UTSW	9	54,301,141 (GRCm39)	missense	probably benign	0.21
R5568:Dmxl2	UTSW	9	54,330,643 (GRCm39)	splice site	probably null
R5733:Dmxl2	UTSW	9	54,283,550 (GRCm39)	missense	possibly damaging	0.64
R5758:Dmxl2	UTSW	9	54,380,248 (GRCm39)	missense	probably benign	0.28
R5759:Dmxl2	UTSW	9	54,282,792 (GRCm39)	missense	probably damaging	1.00
R5893:Dmxl2	UTSW	9	54,294,704 (GRCm39)	missense	possibly damaging	0.64
R6030:Dmxl2	UTSW	9	54,300,957 (GRCm39)	missense	probably benign	0.18
R6030:Dmxl2	UTSW	9	54,300,957 (GRCm39)	missense	probably benign	0.18
R6041:Dmxl2	UTSW	9	54,324,037 (GRCm39)	missense	probably damaging	1.00
R6174:Dmxl2	UTSW	9	54,301,011 (GRCm39)	missense	probably damaging	1.00
R6278:Dmxl2	UTSW	9	54,323,046 (GRCm39)	missense	probably damaging	1.00
R6307:Dmxl2	UTSW	9	54,289,990 (GRCm39)	missense	possibly damaging	0.68
R6349:Dmxl2	UTSW	9	54,327,193 (GRCm39)	missense	possibly damaging	0.89
R6404:Dmxl2	UTSW	9	54,282,820 (GRCm39)	missense	probably damaging	1.00
R6516:Dmxl2	UTSW	9	54,323,960 (GRCm39)	missense	probably damaging	1.00
R6712:Dmxl2	UTSW	9	54,318,908 (GRCm39)	missense	probably damaging	1.00
R6747:Dmxl2	UTSW	9	54,323,372 (GRCm39)	missense	probably damaging	1.00
R6769:Dmxl2	UTSW	9	54,323,808 (GRCm39)	missense	probably damaging	1.00
R6771:Dmxl2	UTSW	9	54,323,808 (GRCm39)	missense	probably damaging	1.00
R6800:Dmxl2	UTSW	9	54,316,467 (GRCm39)	missense	probably damaging	1.00
R6891:Dmxl2	UTSW	9	54,387,664 (GRCm39)	missense	probably damaging	0.99
R6920:Dmxl2	UTSW	9	54,379,496 (GRCm39)	missense	probably damaging	1.00
R6979:Dmxl2	UTSW	9	54,358,163 (GRCm39)	missense	possibly damaging	0.49
R7147:Dmxl2	UTSW	9	54,324,013 (GRCm39)	missense	probably benign	0.06
R7327:Dmxl2	UTSW	9	54,308,869 (GRCm39)	missense	probably damaging	1.00
R7462:Dmxl2	UTSW	9	54,273,916 (GRCm39)	splice site	probably null
R7526:Dmxl2	UTSW	9	54,308,241 (GRCm39)	missense	possibly damaging	0.47
R7569:Dmxl2	UTSW	9	54,323,271 (GRCm39)	missense	possibly damaging	0.51
R7622:Dmxl2	UTSW	9	54,379,502 (GRCm39)	missense	probably damaging	0.99
R7638:Dmxl2	UTSW	9	54,365,078 (GRCm39)	missense	unknown
R7703:Dmxl2	UTSW	9	54,368,370 (GRCm39)	missense	probably benign	0.01
R7768:Dmxl2	UTSW	9	54,288,223 (GRCm39)	missense	probably damaging	1.00
R7926:Dmxl2	UTSW	9	54,335,326 (GRCm39)	missense	probably benign	0.01
R7969:Dmxl2	UTSW	9	54,354,165 (GRCm39)	missense	possibly damaging	0.85
R8007:Dmxl2	UTSW	9	54,290,975 (GRCm39)	nonsense	probably null
R8200:Dmxl2	UTSW	9	54,387,630 (GRCm39)	missense	probably benign
R8311:Dmxl2	UTSW	9	54,354,217 (GRCm39)	missense	probably benign	0.00
R8320:Dmxl2	UTSW	9	54,291,043 (GRCm39)	missense	probably benign
R8377:Dmxl2	UTSW	9	54,286,032 (GRCm39)	missense	probably damaging	1.00
R8400:Dmxl2	UTSW	9	54,291,037 (GRCm39)	missense	probably benign	0.03
R8509:Dmxl2	UTSW	9	54,335,341 (GRCm39)	nonsense	probably null
R8698:Dmxl2	UTSW	9	54,281,953 (GRCm39)	missense	probably benign	0.10
R8768:Dmxl2	UTSW	9	54,301,105 (GRCm39)	missense	possibly damaging	0.83
R8770:Dmxl2	UTSW	9	54,311,298 (GRCm39)	missense	probably benign	0.01
R8799:Dmxl2	UTSW	9	54,327,027 (GRCm39)	critical splice donor site	probably null
R8840:Dmxl2	UTSW	9	54,309,139 (GRCm39)	missense	possibly damaging	0.58
R8898:Dmxl2	UTSW	9	54,308,941 (GRCm39)	missense	probably benign	0.01
R8954:Dmxl2	UTSW	9	54,381,156 (GRCm39)	missense	probably benign	0.04
R9083:Dmxl2	UTSW	9	54,316,548 (GRCm39)	missense	probably benign	0.29
R9114:Dmxl2	UTSW	9	54,307,321 (GRCm39)	missense
R9115:Dmxl2	UTSW	9	54,309,011 (GRCm39)	missense	probably benign
R9263:Dmxl2	UTSW	9	54,358,945 (GRCm39)	missense	probably benign	0.01
R9272:Dmxl2	UTSW	9	54,311,404 (GRCm39)	missense	possibly damaging	0.55
R9577:Dmxl2	UTSW	9	54,323,664 (GRCm39)	missense	unknown
R9673:Dmxl2	UTSW	9	54,294,840 (GRCm39)	missense	probably damaging	1.00
R9722:Dmxl2	UTSW	9	54,323,892 (GRCm39)	missense	probably benign	0.00
R9726:Dmxl2	UTSW	9	54,322,996 (GRCm39)	missense	probably benign	0.09
R9797:Dmxl2	UTSW	9	54,358,187 (GRCm39)	missense	probably benign	0.00
X0064:Dmxl2	UTSW	9	54,308,997 (GRCm39)	missense	probably benign
Z1177:Dmxl2	UTSW	9	54,289,318 (GRCm39)	frame shift	probably null

Posted On

2013-06-21