Mutagenetix > Incidental Mutation

Incidental Mutation 'R7402:Zfp638'

574259

Institutional Source

Beutler Lab

Gene Symbol

Zfp638

Ensembl Gene

ENSMUSG00000030016

Gene Name

zinc finger protein 638

Synonyms

Np220, Zfml

MMRRC Submission

045484-MU

Accession Numbers

Essential gene?

Probably essential (E-score: 0.862) question?

Stock #

R7402 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

83844050-83963855 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 83905670 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Valine to Glutamic Acid at position 41 (V41E)

Ref Sequence

ENSEMBL: ENSMUSP00000145513 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000032088] [ENSMUST00000113835] [ENSMUST00000113836] [ENSMUST00000203273] [ENSMUST00000203324] [ENSMUST00000203455] [ENSMUST00000203891] [ENSMUST00000204415] [ENSMUST00000204202] [ENSMUST00000204751]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000032088

SMART Domains

Protein: ENSMUSP00000032088
Gene: ENSMUSG00000030016

Domain	Start	End	E-Value	Type
low complexity region	16	35	N/A	INTRINSIC
low complexity region	308	324	N/A	INTRINSIC
ZnF_U1	421	455	5.93e0	SMART
ZnF_C2H2	424	448	1.36e1	SMART
low complexity region	482	523	N/A	INTRINSIC
low complexity region	531	555	N/A	INTRINSIC
low complexity region	618	631	N/A	INTRINSIC
RRM	677	747	2.04e-6	SMART
low complexity region	749	763	N/A	INTRINSIC
low complexity region	781	802	N/A	INTRINSIC
RRM	903	972	9.04e-3	SMART
Blast:RRM_2	1007	1075	4e-25	BLAST
low complexity region	1118	1132	N/A	INTRINSIC
low complexity region	1399	1412	N/A	INTRINSIC
low complexity region	1512	1526	N/A	INTRINSIC
low complexity region	1761	1771	N/A	INTRINSIC
ZnF_U1	1873	1907	2.84e-8	SMART
ZnF_C2H2	1876	1900	2.14e0	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000113835

SMART Domains

Protein: ENSMUSP00000109466
Gene: ENSMUSG00000030016

Domain	Start	End	E-Value	Type
low complexity region	16	35	N/A	INTRINSIC
low complexity region	308	324	N/A	INTRINSIC
ZnF_U1	421	455	5.93e0	SMART
ZnF_C2H2	424	448	1.36e1	SMART
low complexity region	482	523	N/A	INTRINSIC
low complexity region	531	555	N/A	INTRINSIC
low complexity region	618	631	N/A	INTRINSIC
RRM	677	747	2.04e-6	SMART
low complexity region	749	763	N/A	INTRINSIC
low complexity region	781	802	N/A	INTRINSIC
RRM	880	949	9.04e-3	SMART
Blast:RRM_2	984	1052	2e-25	BLAST
low complexity region	1095	1109	N/A	INTRINSIC
ZnF_U1	1218	1252	2.84e-8	SMART
ZnF_C2H2	1221	1245	2.14e0	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000113836

SMART Domains

Protein: ENSMUSP00000109467
Gene: ENSMUSG00000030016

Domain	Start	End	E-Value	Type
low complexity region	16	35	N/A	INTRINSIC
low complexity region	308	324	N/A	INTRINSIC
ZnF_U1	421	455	5.93e0	SMART
ZnF_C2H2	424	448	1.36e1	SMART
low complexity region	482	523	N/A	INTRINSIC
low complexity region	531	555	N/A	INTRINSIC
low complexity region	618	631	N/A	INTRINSIC
RRM	677	747	2.04e-6	SMART
low complexity region	749	763	N/A	INTRINSIC
low complexity region	781	802	N/A	INTRINSIC
RRM	903	972	9.04e-3	SMART
Blast:RRM_2	1007	1075	2e-25	BLAST
low complexity region	1118	1132	N/A	INTRINSIC
ZnF_U1	1222	1256	2.84e-8	SMART
ZnF_C2H2	1225	1249	2.14e0	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000203273

Predicted Effect

probably benign
Transcript: ENSMUST00000203324

SMART Domains

Protein: ENSMUSP00000145124
Gene: ENSMUSG00000030016

Domain	Start	End	E-Value	Type
low complexity region	16	35	N/A	INTRINSIC
low complexity region	308	324	N/A	INTRINSIC
ZnF_U1	421	455	3.5e-2	SMART
ZnF_C2H2	424	448	5.9e-2	SMART
low complexity region	482	523	N/A	INTRINSIC
low complexity region	531	555	N/A	INTRINSIC
low complexity region	618	631	N/A	INTRINSIC
RRM	677	747	9.1e-9	SMART
low complexity region	749	763	N/A	INTRINSIC
low complexity region	781	802	N/A	INTRINSIC
RRM	903	972	3.9e-5	SMART
Blast:RRM_2	1007	1075	2e-25	BLAST
low complexity region	1118	1132	N/A	INTRINSIC
ZnF_U1	1220	1254	1.7e-10	SMART
ZnF_C2H2	1223	1247	8.9e-3	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000203455

SMART Domains

Protein: ENSMUSP00000145047
Gene: ENSMUSG00000030016

Domain	Start	End	E-Value	Type
low complexity region	16	35	N/A	INTRINSIC
low complexity region	308	324	N/A	INTRINSIC
ZnF_C2H2	424	448	1.36e1	SMART
low complexity region	482	523	N/A	INTRINSIC
low complexity region	531	555	N/A	INTRINSIC
low complexity region	618	631	N/A	INTRINSIC
RRM	677	747	2.04e-6	SMART
low complexity region	749	763	N/A	INTRINSIC
low complexity region	781	802	N/A	INTRINSIC
internal_repeat_1	819	891	3.29e-10	PROSPERO

Predicted Effect

probably benign
Transcript: ENSMUST00000203891

SMART Domains

Protein: ENSMUSP00000144939
Gene: ENSMUSG00000030016

Domain	Start	End	E-Value	Type
low complexity region	16	35	N/A	INTRINSIC
low complexity region	308	324	N/A	INTRINSIC
ZnF_U1	421	455	3.5e-2	SMART
ZnF_C2H2	424	448	5.9e-2	SMART
low complexity region	482	523	N/A	INTRINSIC
low complexity region	531	555	N/A	INTRINSIC
low complexity region	618	631	N/A	INTRINSIC
RRM	677	747	9.1e-9	SMART
low complexity region	749	763	N/A	INTRINSIC
low complexity region	781	802	N/A	INTRINSIC
RRM	903	972	3.9e-5	SMART
Blast:RRM_2	1007	1075	2e-25	BLAST
low complexity region	1118	1132	N/A	INTRINSIC
ZnF_U1	1186	1220	1.7e-10	SMART
ZnF_C2H2	1189	1213	8.9e-3	SMART

Predicted Effect

possibly damaging
Transcript: ENSMUST00000204415
AA Change: V41E

PolyPhen 2 Score 0.915 (Sensitivity: 0.81; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000145513
Gene: ENSMUSG00000030016
AA Change: V41E

Domain	Start	End	E-Value	Type
low complexity region	2	21	N/A	INTRINSIC
low complexity region	112	131	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000204202

SMART Domains

Protein: ENSMUSP00000145170
Gene: ENSMUSG00000030016

Domain	Start	End	E-Value	Type
low complexity region	16	35	N/A	INTRINSIC
low complexity region	308	324	N/A	INTRINSIC
ZnF_C2H2	424	448	5.9e-2	SMART
low complexity region	482	523	N/A	INTRINSIC
low complexity region	531	555	N/A	INTRINSIC
low complexity region	618	631	N/A	INTRINSIC
RRM	677	747	9.1e-9	SMART
low complexity region	749	763	N/A	INTRINSIC
low complexity region	781	802	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000204751

SMART Domains

Protein: ENSMUSP00000144989
Gene: ENSMUSG00000030016

Domain	Start	End	E-Value	Type
low complexity region	16	35	N/A	INTRINSIC
low complexity region	308	324	N/A	INTRINSIC
ZnF_U1	421	455	5.93e0	SMART
ZnF_C2H2	424	448	1.36e1	SMART
low complexity region	482	523	N/A	INTRINSIC
low complexity region	531	555	N/A	INTRINSIC
low complexity region	618	631	N/A	INTRINSIC
RRM	677	747	2.04e-6	SMART
low complexity region	749	763	N/A	INTRINSIC
low complexity region	781	802	N/A	INTRINSIC
RRM	903	972	9.04e-3	SMART
Blast:RRM_2	1007	1075	4e-25	BLAST
low complexity region	1118	1132	N/A	INTRINSIC
low complexity region	1399	1412	N/A	INTRINSIC
low complexity region	1512	1526	N/A	INTRINSIC
low complexity region	1761	1771	N/A	INTRINSIC
ZnF_U1	1873	1907	2.84e-8	SMART
ZnF_C2H2	1876	1900	2.14e0	SMART

Coding Region Coverage

1x: 100.0%
3x: 100.0%
10x: 99.8%
20x: 99.3%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a nucleoplasmic protein. It binds cytidine-rich sequences in double-stranded DNA. This protein has three types of domains: MH1, MH2 (repeated three times) and MH3. It is associated with packaging, transferring, or processing transcripts. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]

Allele List at MGI

Other mutations in this stock

Total: 98 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcc4	G	T	14: 118,943,487 (GRCm39)	P12Q	probably damaging	Het
Acsf3	A	G	8: 123,507,163 (GRCm39)	Y152C	probably damaging	Het
Adam22	T	A	5: 8,145,049 (GRCm39)	Q803L	possibly damaging	Het
Adamtsl3	G	A	7: 82,227,825 (GRCm39)	V1337I	probably damaging	Het
Adra1b	T	C	11: 43,666,845 (GRCm39)	D464G	possibly damaging	Het
Alpk3	T	A	7: 80,726,660 (GRCm39)	I115K	probably benign	Het
Amdhd2	A	G	17: 24,380,657 (GRCm39)	S96P		Het
Ankib1	T	G	5: 3,819,586 (GRCm39)	D111A	probably benign	Het
Arhgef2	A	G	3: 88,540,873 (GRCm39)	D216G	probably damaging	Het
Astn1	A	T	1: 158,380,425 (GRCm39)		probably benign	Het
Atosa	C	A	9: 74,913,668 (GRCm39)	Y107*	probably null	Het
Atrn	T	A	2: 130,789,520 (GRCm39)	W328R	probably damaging	Het
Atxn7	A	T	14: 14,095,427 (GRCm38)	H375L	probably damaging	Het
Btaf1	A	T	19: 36,980,915 (GRCm39)	N1579Y	probably damaging	Het
Cacna1b	A	T	2: 24,497,671 (GRCm39)	L2079Q	probably benign	Het
Ccdc102a	T	C	8: 95,629,981 (GRCm39)	K520R	probably damaging	Het
Cd2ap	T	C	17: 43,116,054 (GRCm39)	H602R	possibly damaging	Het
Cdkn2aip	A	G	8: 48,164,408 (GRCm39)	V435A	possibly damaging	Het
Cenpf	A	T	1: 189,391,575 (GRCm39)	Y735*	probably null	Het
Cep350	T	A	1: 155,803,961 (GRCm39)	I1041L	probably benign	Het
Ckap4	A	G	10: 84,363,863 (GRCm39)	V400A	probably damaging	Het
Comp	T	A	8: 70,829,854 (GRCm39)	D359E	probably benign	Het
Coq10b	A	C	1: 55,100,500 (GRCm39)	K61N	probably benign	Het
Csmd2	G	A	4: 128,215,889 (GRCm39)	S548N		Het
Csmd2	A	C	4: 128,215,888 (GRCm39)	S548R		Het
Ctif	A	G	18: 75,744,807 (GRCm39)	I99T	probably benign	Het
Ctns	T	G	11: 73,083,903 (GRCm39)	T40P	possibly damaging	Het
Cyp11b1	C	T	15: 74,712,674 (GRCm39)	R129H	probably damaging	Het
Cyp2c68	A	T	19: 39,729,318 (GRCm39)	N56K	probably benign	Het
D6Wsu163e	A	G	6: 126,938,968 (GRCm39)	K401R	probably damaging	Het
Dstn	T	A	2: 143,780,368 (GRCm39)	C23S	probably benign	Het
Fam72a	A	T	1: 131,466,613 (GRCm39)	E132D	probably damaging	Het
Fam72a	G	T	1: 131,466,614 (GRCm39)	E133*	probably null	Het
Gbp8	T	A	5: 105,179,161 (GRCm39)	I113F	probably damaging	Het
Gm3095	A	T	14: 15,170,332 (GRCm39)	R60S	possibly damaging	Het
Gpa33	A	T	1: 165,980,263 (GRCm39)	M109L	probably damaging	Het
Grik2	A	G	10: 49,411,493 (GRCm39)	L215P	probably damaging	Het
Gucy2g	A	C	19: 55,194,725 (GRCm39)	F897L	probably damaging	Het
Hinfp	A	G	9: 44,209,314 (GRCm39)	L295P	probably damaging	Het
Ift122	T	C	6: 115,871,283 (GRCm39)	V526A	probably benign	Het
Ighv5-12	T	C	12: 113,665,853 (GRCm39)	T82A	probably benign	Het
Il18rap	T	A	1: 40,564,111 (GRCm39)	S76R	probably benign	Het
Itga6	A	T	2: 71,683,897 (GRCm39)	N1045I	probably benign	Het
Kctd21	A	T	7: 96,996,970 (GRCm39)	I148F	possibly damaging	Het
Kif28	T	A	1: 179,567,644 (GRCm39)	H42L	probably benign	Het
Kmt2c	A	C	5: 25,600,418 (GRCm39)	C326W	probably damaging	Het
Knl1	T	A	2: 118,925,707 (GRCm39)	L1912*	probably null	Het
Lrfn1	A	T	7: 28,158,947 (GRCm39)	I289F	probably damaging	Het
Lrriq1	T	C	10: 103,057,185 (GRCm39)	K205R	possibly damaging	Het
Mbd5	A	T	2: 49,147,566 (GRCm39)	N592I	probably damaging	Het
Mbl2	A	G	19: 30,216,802 (GRCm39)	N205D	possibly damaging	Het
Mcm4	C	A	16: 15,455,042 (GRCm39)	M1I	probably null	Het
Mgat4a	T	A	1: 37,493,865 (GRCm39)	H327L	probably damaging	Het
Miox	A	G	15: 89,219,206 (GRCm39)	D16G	probably benign	Het
Mvk	C	A	5: 114,594,039 (GRCm39)	P298Q	possibly damaging	Het
Nol6	A	G	4: 41,118,699 (GRCm39)	L726P	probably damaging	Het
Nos1	T	C	5: 118,087,880 (GRCm39)	I1381T	probably benign	Het
Nup98	A	T	7: 101,784,144 (GRCm39)	S1063T	probably benign	Het
Obscn	T	G	11: 58,886,275 (GRCm39)	M7862L	unknown	Het
Obsl1	T	C	1: 75,464,348 (GRCm39)	T1653A	probably benign	Het
Odr4	A	G	1: 150,262,107 (GRCm39)		probably null	Het
Or4c105	G	T	2: 88,647,687 (GRCm39)	M57I	probably damaging	Het
Or8g53	T	A	9: 39,683,260 (GRCm39)	T279S	probably benign	Het
Or8u9	A	G	2: 86,001,546 (GRCm39)	I205T	probably benign	Het
Or9q2	C	T	19: 13,772,358 (GRCm39)	V206I	probably damaging	Het
Pcdhb20	A	G	18: 37,638,005 (GRCm39)	Y177C	probably benign	Het
Pcdhb3	A	C	18: 37,434,657 (GRCm39)	I208L	probably benign	Het
Phlpp1	G	T	1: 106,317,420 (GRCm39)	G1214W	probably damaging	Het
Ppp4r3a	A	T	12: 101,025,053 (GRCm39)	S149T	possibly damaging	Het
Pxdn	T	C	12: 30,052,438 (GRCm39)	C872R	probably damaging	Het
Rarb	A	G	14: 16,548,419 (GRCm38)	C101R	probably damaging	Het
Rcor3	A	C	1: 191,812,283 (GRCm39)	V114G	probably benign	Het
Rnpepl1	A	G	1: 92,847,372 (GRCm39)	Q653R	probably benign	Het
Rpap2	T	A	5: 107,768,324 (GRCm39)	Y387*	probably null	Het
Rttn	C	T	18: 89,004,035 (GRCm39)	T343M	possibly damaging	Het
Samd11	T	C	4: 156,333,230 (GRCm39)	T333A	probably benign	Het
Six5	T	C	7: 18,828,968 (GRCm39)	L136P	probably damaging	Het
Slc12a5	T	A	2: 164,824,852 (GRCm39)	M419K	probably benign	Het
Slc22a21	T	C	11: 53,851,226 (GRCm39)	M179V	probably benign	Het
Slc35a4	A	G	18: 36,813,570 (GRCm39)	D6G	unknown	Het
Spdye4c	A	T	2: 128,434,261 (GRCm39)	M1L	probably benign	Het
Svep1	A	T	4: 58,069,699 (GRCm39)	C2696S	possibly damaging	Het
Tceanc2	T	C	4: 107,004,893 (GRCm39)	N85S	probably benign	Het
Teddm2	G	C	1: 153,726,344 (GRCm39)	L124V	probably benign	Het
Teddm2	A	T	1: 153,726,343 (GRCm39)	L124Q	probably damaging	Het
Tgfbr1	T	A	4: 47,405,623 (GRCm39)	W409R	probably damaging	Het
Tkt	A	G	14: 30,280,755 (GRCm39)	D62G	probably damaging	Het
Tnrc6b	T	A	15: 80,768,501 (GRCm39)	V1054D	probably damaging	Het
Trpm7	C	A	2: 126,641,126 (GRCm39)	L1564F	probably damaging	Het
Vmn1r43	A	T	6: 89,846,803 (GRCm39)	C228S	probably benign	Het
Vmn2r106	T	C	17: 20,487,883 (GRCm39)	R839G	probably damaging	Het
Vmn2r5	G	A	3: 64,403,176 (GRCm39)	T523I	probably benign	Het
Vwa3b	C	T	1: 37,153,678 (GRCm39)	Q507*	probably null	Het
Wrn	C	G	8: 33,738,994 (GRCm39)	W1278S	probably benign	Het
Zfp281	T	G	1: 136,553,190 (GRCm39)	L56R	probably damaging	Het
Zfp407	G	A	18: 84,579,661 (GRCm39)	T484I	probably benign	Het
Zfp451	T	C	1: 33,852,843 (GRCm39)	T24A	probably benign	Het
Zfp607b	T	A	7: 27,392,919 (GRCm39)	F16I	probably damaging	Het

Other mutations in Zfp638

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00335:Zfp638	APN	6	83,956,700 (GRCm39)	missense	probably damaging	1.00
IGL00514:Zfp638	APN	6	83,933,680 (GRCm39)	missense	probably damaging	1.00
IGL00705:Zfp638	APN	6	83,954,112 (GRCm39)	missense	probably damaging	1.00
IGL00785:Zfp638	APN	6	83,906,146 (GRCm39)	missense	probably damaging	1.00
IGL01068:Zfp638	APN	6	83,911,976 (GRCm39)	missense	probably damaging	1.00
IGL01084:Zfp638	APN	6	83,921,780 (GRCm39)	missense	probably benign	0.01
IGL01570:Zfp638	APN	6	83,924,829 (GRCm39)	missense	probably damaging	1.00
IGL01758:Zfp638	APN	6	83,956,508 (GRCm39)	missense	probably damaging	0.96
IGL02345:Zfp638	APN	6	83,961,857 (GRCm39)	missense	probably damaging	1.00
IGL02939:Zfp638	APN	6	83,946,214 (GRCm39)	missense	probably damaging	0.98
IGL03007:Zfp638	APN	6	83,961,866 (GRCm39)	missense	probably damaging	1.00
IGL03118:Zfp638	APN	6	83,912,000 (GRCm39)	splice site	probably benign
IGL03135:Zfp638	APN	6	83,919,857 (GRCm39)	missense	probably damaging	1.00
IGL03264:Zfp638	APN	6	83,923,229 (GRCm39)	missense	probably benign	0.04
R0190:Zfp638	UTSW	6	83,905,946 (GRCm39)	missense	probably damaging	1.00
R0200:Zfp638	UTSW	6	83,944,336 (GRCm39)	missense	probably damaging	1.00
R0766:Zfp638	UTSW	6	83,906,023 (GRCm39)	missense	probably damaging	1.00
R0801:Zfp638	UTSW	6	83,949,220 (GRCm39)	unclassified	probably benign
R0938:Zfp638	UTSW	6	83,961,023 (GRCm39)	missense	probably benign	0.16
R1312:Zfp638	UTSW	6	83,906,023 (GRCm39)	missense	probably damaging	1.00
R1458:Zfp638	UTSW	6	83,921,638 (GRCm39)	missense	probably damaging	1.00
R1584:Zfp638	UTSW	6	83,955,047 (GRCm39)	splice site	probably null
R1634:Zfp638	UTSW	6	83,956,894 (GRCm39)	splice site	probably null
R1651:Zfp638	UTSW	6	83,931,719 (GRCm39)	missense	probably benign	0.00
R2079:Zfp638	UTSW	6	83,930,371 (GRCm39)	critical splice donor site	probably null
R2134:Zfp638	UTSW	6	83,905,964 (GRCm39)	missense	probably damaging	1.00
R2142:Zfp638	UTSW	6	83,963,578 (GRCm39)	missense	probably damaging	1.00
R2201:Zfp638	UTSW	6	83,906,500 (GRCm39)	missense	probably damaging	1.00
R2422:Zfp638	UTSW	6	83,943,421 (GRCm39)	splice site	probably benign
R4353:Zfp638	UTSW	6	83,961,041 (GRCm39)	missense	probably damaging	0.97
R4681:Zfp638	UTSW	6	83,958,719 (GRCm39)	missense	possibly damaging	0.50
R4716:Zfp638	UTSW	6	83,956,544 (GRCm39)	nonsense	probably null
R4807:Zfp638	UTSW	6	83,920,040 (GRCm39)	missense	probably damaging	1.00
R4850:Zfp638	UTSW	6	83,956,457 (GRCm39)	missense	possibly damaging	0.92
R5079:Zfp638	UTSW	6	83,906,438 (GRCm39)	missense	probably benign	0.03
R5236:Zfp638	UTSW	6	83,953,557 (GRCm39)	nonsense	probably null
R5323:Zfp638	UTSW	6	83,939,076 (GRCm39)	missense	probably damaging	0.96
R5426:Zfp638	UTSW	6	83,953,396 (GRCm39)	missense	probably damaging	1.00
R5557:Zfp638	UTSW	6	83,944,345 (GRCm39)	missense	probably damaging	1.00
R5570:Zfp638	UTSW	6	83,956,170 (GRCm39)	missense	probably damaging	1.00
R5614:Zfp638	UTSW	6	83,906,623 (GRCm39)	missense	probably damaging	1.00
R5662:Zfp638	UTSW	6	83,920,111 (GRCm39)	missense	probably damaging	0.97
R5685:Zfp638	UTSW	6	83,906,969 (GRCm39)	missense	probably damaging	1.00
R5689:Zfp638	UTSW	6	83,906,054 (GRCm39)	missense	probably damaging	1.00
R5783:Zfp638	UTSW	6	83,921,829 (GRCm39)	missense	possibly damaging	0.92
R5856:Zfp638	UTSW	6	83,954,047 (GRCm39)	missense	probably damaging	1.00
R6310:Zfp638	UTSW	6	83,844,212 (GRCm39)	missense	possibly damaging	0.90
R6477:Zfp638	UTSW	6	83,942,560 (GRCm39)	missense	probably damaging	1.00
R6557:Zfp638	UTSW	6	83,907,092 (GRCm39)	missense	probably damaging	1.00
R7084:Zfp638	UTSW	6	83,930,108 (GRCm39)	missense	possibly damaging	0.50
R7101:Zfp638	UTSW	6	83,931,708 (GRCm39)	missense	probably benign	0.00
R7141:Zfp638	UTSW	6	83,844,181 (GRCm39)	missense	unknown
R7368:Zfp638	UTSW	6	83,906,437 (GRCm39)	missense	possibly damaging	0.60
R7455:Zfp638	UTSW	6	83,907,127 (GRCm39)	missense	probably damaging	1.00
R7762:Zfp638	UTSW	6	83,953,254 (GRCm39)	missense	probably damaging	1.00
R7773:Zfp638	UTSW	6	83,956,196 (GRCm39)	missense	probably damaging	1.00
R8090:Zfp638	UTSW	6	83,906,801 (GRCm39)	missense	probably damaging	0.99
R8154:Zfp638	UTSW	6	83,954,391 (GRCm39)	missense	probably damaging	1.00
R8161:Zfp638	UTSW	6	83,906,713 (GRCm39)	missense	possibly damaging	0.85
R8327:Zfp638	UTSW	6	83,905,679 (GRCm39)	missense	probably damaging	0.99
R8384:Zfp638	UTSW	6	83,956,747 (GRCm39)	missense	probably benign	0.28
R8703:Zfp638	UTSW	6	83,954,143 (GRCm39)	missense	probably damaging	0.96
R8738:Zfp638	UTSW	6	83,931,745 (GRCm39)	critical splice donor site	probably null
R8865:Zfp638	UTSW	6	83,954,035 (GRCm39)	missense	possibly damaging	0.91
R8874:Zfp638	UTSW	6	83,946,135 (GRCm39)	missense	probably damaging	1.00
R9080:Zfp638	UTSW	6	83,844,155 (GRCm39)	missense	unknown
R9113:Zfp638	UTSW	6	83,953,894 (GRCm39)	missense	probably damaging	0.96
R9574:Zfp638	UTSW	6	83,956,680 (GRCm39)	missense	probably damaging	1.00
R9661:Zfp638	UTSW	6	83,923,320 (GRCm39)	missense	probably damaging	0.99
R9722:Zfp638	UTSW	6	83,923,301 (GRCm39)	missense	probably damaging	1.00
R9745:Zfp638	UTSW	6	83,921,795 (GRCm39)	missense	probably benign	0.27
Z1088:Zfp638	UTSW	6	83,921,793 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- ACAGCTCGGCAATGTACATG -3'
(R):5'- GTCTCGACATGGCTACTTTCAAG -3'

Sequencing Primer
(F):5'- CAGCTCGGCAATGTACATGAACTTG -3'
(R):5'- GGCTACTTTCAAGAATGCCTG -3'

Posted On

2019-09-13