Incidental Mutation 'R9036:Zfp106'
| ID |
687362 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Zfp106
|
| Ensembl Gene |
ENSMUSG00000027288 |
| Gene Name |
zinc finger protein 106 |
| Synonyms |
Cd-1, H3a, Sh3bp3, sirm |
| MMRRC Submission |
068865-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R9036 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
120337301-120394324 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 120369906 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Phenylalanine
at position 62
(I62F)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000055602
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000055241]
[ENSMUST00000135625]
[ENSMUST00000171215]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000055241
AA Change: I62F
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000055602
Gene: ENSMUSG00000027288
AA Change: I62F
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
5 |
29 |
1.51e0 |
SMART |
|
ZnF_C2H2
|
43 |
67 |
7.18e1 |
SMART |
|
low complexity region
|
75 |
92 |
N/A |
INTRINSIC |
|
low complexity region
|
141 |
152 |
N/A |
INTRINSIC |
|
low complexity region
|
199 |
212 |
N/A |
INTRINSIC |
|
low complexity region
|
466 |
480 |
N/A |
INTRINSIC |
|
coiled coil region
|
800 |
823 |
N/A |
INTRINSIC |
|
low complexity region
|
842 |
856 |
N/A |
INTRINSIC |
|
low complexity region
|
1049 |
1062 |
N/A |
INTRINSIC |
|
low complexity region
|
1312 |
1321 |
N/A |
INTRINSIC |
|
low complexity region
|
1361 |
1373 |
N/A |
INTRINSIC |
|
low complexity region
|
1389 |
1409 |
N/A |
INTRINSIC |
|
WD40
|
1525 |
1562 |
9.24e-4 |
SMART |
|
WD40
|
1565 |
1607 |
1.83e-7 |
SMART |
|
PQQ
|
1587 |
1618 |
3.42e2 |
SMART |
|
WD40
|
1651 |
1691 |
3.45e-1 |
SMART |
|
PQQ
|
1671 |
1702 |
9.14e1 |
SMART |
|
WD40
|
1694 |
1731 |
2.12e-3 |
SMART |
|
PQQ
|
1711 |
1742 |
6.42e0 |
SMART |
|
WD40
|
1734 |
1771 |
6e-3 |
SMART |
|
PQQ
|
1751 |
1782 |
5.7e2 |
SMART |
|
WD40
|
1774 |
1811 |
3.58e-1 |
SMART |
|
ZnF_C2H2
|
1818 |
1843 |
5.34e-1 |
SMART |
|
ZnF_C2H2
|
1851 |
1879 |
1.31e2 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000135625
|
| SMART Domains |
Protein: ENSMUSP00000126939
Gene: ENSMUSG00000027288
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
5 |
29 |
1.51e0 |
SMART |
|
low complexity region
|
53 |
67 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000167241
|
| SMART Domains |
Protein: ENSMUSP00000127803
Gene: ENSMUSG00000027288
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
4 |
28 |
1.51e0 |
SMART |
|
low complexity region
|
74 |
85 |
N/A |
INTRINSIC |
|
low complexity region
|
132 |
145 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000171215
AA Change: I39F
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000128995
Gene: ENSMUSG00000027288
AA Change: I39F
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
20 |
44 |
7.18e1 |
SMART |
|
low complexity region
|
52 |
69 |
N/A |
INTRINSIC |
|
low complexity region
|
118 |
129 |
N/A |
INTRINSIC |
|
low complexity region
|
176 |
189 |
N/A |
INTRINSIC |
|
low complexity region
|
443 |
457 |
N/A |
INTRINSIC |
|
coiled coil region
|
777 |
800 |
N/A |
INTRINSIC |
|
low complexity region
|
819 |
833 |
N/A |
INTRINSIC |
|
low complexity region
|
1026 |
1039 |
N/A |
INTRINSIC |
|
low complexity region
|
1289 |
1298 |
N/A |
INTRINSIC |
|
low complexity region
|
1338 |
1350 |
N/A |
INTRINSIC |
|
low complexity region
|
1366 |
1386 |
N/A |
INTRINSIC |
|
WD40
|
1502 |
1539 |
9.24e-4 |
SMART |
|
WD40
|
1542 |
1584 |
1.83e-7 |
SMART |
|
PQQ
|
1564 |
1595 |
3.42e2 |
SMART |
|
WD40
|
1628 |
1668 |
3.45e-1 |
SMART |
|
PQQ
|
1648 |
1679 |
9.14e1 |
SMART |
|
WD40
|
1671 |
1708 |
2.12e-3 |
SMART |
|
PQQ
|
1688 |
1719 |
6.42e0 |
SMART |
|
WD40
|
1711 |
1748 |
6e-3 |
SMART |
|
PQQ
|
1728 |
1759 |
5.7e2 |
SMART |
|
WD40
|
1751 |
1788 |
3.58e-1 |
SMART |
|
ZnF_C2H2
|
1795 |
1820 |
5.34e-1 |
SMART |
|
ZnF_C2H2
|
1828 |
1856 |
1.31e2 |
SMART |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 99.9%
- 10x: 99.6%
- 20x: 98.6%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a null allele exhibit an abnormal gait, progressive motor deficits, kyphosis, weight loss, severe adult-onset degenerative sensory-motor axonopathy, mitochondrial dysfunction, and premature death. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 93 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acsl6 |
G |
T |
11: 54,227,840 (GRCm39) |
|
probably null |
Het |
| Anapc5 |
A |
G |
5: 122,957,716 (GRCm39) |
L69P |
possibly damaging |
Het |
| Aoc1l3 |
CCTAAATTTCCTATCCCGATCAGCAAGGGTGGCCCTCGAGTGCCCCAGCCCCATGCTAAATTTCC |
CCTAAATTTCC |
6: 48,965,074 (GRCm39) |
|
probably benign |
Het |
| Arfgef1 |
A |
T |
1: 10,259,055 (GRCm39) |
S681T |
probably benign |
Het |
| Arhgef19 |
A |
G |
4: 140,976,549 (GRCm39) |
D437G |
probably damaging |
Het |
| Arhgef25 |
A |
G |
10: 127,019,089 (GRCm39) |
V576A |
probably benign |
Het |
| Arl5b |
T |
C |
2: 15,073,012 (GRCm39) |
|
probably null |
Het |
| Atg10 |
T |
A |
13: 91,189,071 (GRCm39) |
T80S |
probably benign |
Het |
| BC034090 |
A |
G |
1: 155,117,419 (GRCm39) |
V233A |
possibly damaging |
Het |
| Bicdl2 |
C |
T |
17: 23,887,158 (GRCm39) |
R482C |
probably damaging |
Het |
| Ccdc63 |
G |
A |
5: 122,247,346 (GRCm39) |
P500S |
probably benign |
Het |
| Ccn2 |
A |
T |
10: 24,472,647 (GRCm39) |
T186S |
probably benign |
Het |
| Ccng1 |
A |
T |
11: 40,643,078 (GRCm39) |
I123K |
possibly damaging |
Het |
| Ccp110 |
C |
T |
7: 118,324,680 (GRCm39) |
S734F |
probably damaging |
Het |
| Cds2 |
T |
C |
2: 132,139,614 (GRCm39) |
|
probably null |
Het |
| Cenpw |
G |
A |
10: 30,074,523 (GRCm39) |
T58I |
probably benign |
Het |
| Cfap61 |
T |
A |
2: 145,850,839 (GRCm39) |
L326I |
probably benign |
Het |
| Cgn |
T |
A |
3: 94,674,551 (GRCm39) |
Q862L |
possibly damaging |
Het |
| Cntrl |
T |
A |
2: 35,016,071 (GRCm39) |
D362E |
probably damaging |
Het |
| Col22a1 |
C |
T |
15: 71,762,431 (GRCm39) |
G76E |
probably damaging |
Het |
| Cplane1 |
C |
T |
15: 8,252,622 (GRCm39) |
T1948I |
possibly damaging |
Het |
| Crip2 |
A |
G |
12: 113,108,030 (GRCm39) |
T140A |
probably benign |
Het |
| Csde1 |
T |
C |
3: 102,950,976 (GRCm39) |
V229A |
probably damaging |
Het |
| Cyp2d34 |
A |
G |
15: 82,500,523 (GRCm39) |
F439L |
probably damaging |
Het |
| Dync1h1 |
A |
G |
12: 110,606,186 (GRCm39) |
T2419A |
probably benign |
Het |
| Dync2h1 |
A |
T |
9: 7,051,495 (GRCm39) |
F3147I |
probably damaging |
Het |
| Dynlt1f |
T |
C |
17: 6,916,707 (GRCm39) |
T101A |
probably benign |
Het |
| Efcab3 |
A |
G |
11: 104,927,601 (GRCm39) |
H4790R |
probably benign |
Het |
| Efcab8 |
G |
A |
2: 153,622,888 (GRCm39) |
S19N |
|
Het |
| Eno2 |
A |
T |
6: 124,740,091 (GRCm39) |
I315K |
possibly damaging |
Het |
| Erich3 |
A |
G |
3: 154,468,886 (GRCm39) |
T1113A |
unknown |
Het |
| Fam217a |
A |
T |
13: 35,095,007 (GRCm39) |
Y251N |
possibly damaging |
Het |
| Fcrlb |
A |
T |
1: 170,734,938 (GRCm39) |
H396Q |
probably benign |
Het |
| Fcsk |
A |
G |
8: 111,614,064 (GRCm39) |
V693A |
probably benign |
Het |
| Fgd5 |
A |
T |
6: 92,046,447 (GRCm39) |
K1397* |
probably null |
Het |
| Frem1 |
C |
A |
4: 82,831,785 (GRCm39) |
L2010F |
probably benign |
Het |
| Fzd8 |
A |
G |
18: 9,214,661 (GRCm39) |
Y581C |
probably damaging |
Het |
| Gcc2 |
T |
C |
10: 58,106,411 (GRCm39) |
V549A |
possibly damaging |
Het |
| Gcnt4 |
G |
A |
13: 97,083,042 (GRCm39) |
V113I |
probably benign |
Het |
| Gldn |
A |
G |
9: 54,245,747 (GRCm39) |
I433V |
probably benign |
Het |
| Gm3336 |
A |
G |
8: 71,173,069 (GRCm39) |
D27G |
unknown |
Het |
| Gm6133 |
T |
A |
18: 78,393,146 (GRCm39) |
Y47N |
probably damaging |
Het |
| Gm8257 |
A |
T |
14: 44,893,877 (GRCm39) |
N62K |
probably benign |
Het |
| Gpr18 |
T |
G |
14: 122,149,667 (GRCm39) |
R119S |
probably damaging |
Het |
| Grm5 |
A |
T |
7: 87,685,397 (GRCm39) |
I505F |
possibly damaging |
Het |
| Hdgfl1 |
T |
C |
13: 26,953,428 (GRCm39) |
E215G |
probably benign |
Het |
| Heg1 |
T |
A |
16: 33,527,339 (GRCm39) |
C100S |
probably benign |
Het |
| Isg20l2 |
T |
C |
3: 87,839,302 (GRCm39) |
V171A |
probably benign |
Het |
| Lrrc49 |
A |
T |
9: 60,495,150 (GRCm39) |
C694S |
probably benign |
Het |
| Map7d1 |
A |
T |
4: 126,133,911 (GRCm39) |
I217N |
probably damaging |
Het |
| Mbnl2 |
A |
T |
14: 120,562,712 (GRCm39) |
Q21L |
probably benign |
Het |
| Mfsd10 |
A |
T |
5: 34,792,751 (GRCm39) |
F220Y |
probably benign |
Het |
| Mmp1b |
A |
C |
9: 7,387,909 (GRCm39) |
N28K |
probably null |
Het |
| Muc16 |
A |
T |
9: 18,555,975 (GRCm39) |
N3439K |
unknown |
Het |
| Myef2l |
C |
A |
3: 10,157,341 (GRCm39) |
Q495K |
unknown |
Het |
| Myo9a |
A |
T |
9: 59,687,584 (GRCm39) |
K230* |
probably null |
Het |
| Mysm1 |
T |
C |
4: 94,835,294 (GRCm39) |
T790A |
probably benign |
Het |
| Nell2 |
C |
T |
15: 95,194,117 (GRCm39) |
C532Y |
probably damaging |
Het |
| Nmnat1 |
T |
A |
4: 149,553,482 (GRCm39) |
N210I |
probably damaging |
Het |
| Or14j7 |
T |
G |
17: 38,235,168 (GRCm39) |
V237G |
probably benign |
Het |
| Or2aj6 |
A |
T |
16: 19,443,295 (GRCm39) |
L185* |
probably null |
Het |
| Or4k41 |
T |
C |
2: 111,280,343 (GRCm39) |
I286T |
probably damaging |
Het |
| Or7g16 |
G |
A |
9: 18,727,569 (GRCm39) |
T7I |
probably damaging |
Het |
| Pabpc6 |
T |
C |
17: 9,888,281 (GRCm39) |
D90G |
probably damaging |
Het |
| Pacs2 |
A |
T |
12: 113,026,104 (GRCm39) |
I554F |
possibly damaging |
Het |
| Padi3 |
C |
A |
4: 140,523,004 (GRCm39) |
V323L |
probably benign |
Het |
| Piezo1 |
G |
A |
8: 123,215,090 (GRCm39) |
P1484L |
|
Het |
| Pogk |
A |
G |
1: 166,227,254 (GRCm39) |
I299T |
possibly damaging |
Het |
| Ptprk |
A |
G |
10: 28,461,928 (GRCm39) |
I1164V |
probably benign |
Het |
| Raph1 |
A |
G |
1: 60,542,124 (GRCm39) |
M278T |
unknown |
Het |
| Rasa3 |
T |
A |
8: 13,645,851 (GRCm39) |
Q163L |
probably benign |
Het |
| Rbm6 |
T |
A |
9: 107,660,911 (GRCm39) |
K884I |
probably damaging |
Het |
| Rtl1 |
A |
G |
12: 109,559,691 (GRCm39) |
V716A |
probably benign |
Het |
| Sag |
A |
G |
1: 87,749,054 (GRCm39) |
K151R |
probably damaging |
Het |
| Scara5 |
G |
A |
14: 66,000,197 (GRCm39) |
V456M |
probably benign |
Het |
| Selplg |
GTCTGCCTCCATGGGTGCTGGCTGCGAGGTCTCTGCCTCCATGGGTGCTGGCTGCGAGGTCTCTGCCTCCATGGGTGCTGGCTGCGAGGTCTCTGCCTCCATGGGTGCTGGCTGCGAGGTCTCT |
GTCTGCCTCCATGGGTGCTGGCTGCGAGGTCTCTGCCTCCATGGGTGCTGGCTGCGAGGTCTCTGCCTCCATGGGTGCTGGCTGCGAGGTCTCT |
5: 113,957,756 (GRCm39) |
|
probably benign |
Het |
| Slc4a1 |
A |
T |
11: 102,243,279 (GRCm39) |
V784D |
probably damaging |
Het |
| Sstr1 |
T |
C |
12: 58,259,569 (GRCm39) |
I64T |
possibly damaging |
Het |
| Steap1 |
A |
G |
5: 5,790,708 (GRCm39) |
I80T |
probably benign |
Het |
| Tbc1d24 |
T |
A |
17: 24,427,491 (GRCm39) |
D157V |
probably benign |
Het |
| Thsd7a |
T |
C |
6: 12,418,249 (GRCm39) |
E660G |
|
Het |
| Trappc3l |
A |
G |
10: 33,932,786 (GRCm39) |
|
probably benign |
Het |
| Tsc22d2 |
T |
C |
3: 58,323,497 (GRCm39) |
S130P |
probably benign |
Het |
| Tti2 |
T |
A |
8: 31,645,814 (GRCm39) |
I376N |
probably damaging |
Het |
| Ttll2 |
C |
A |
17: 7,619,054 (GRCm39) |
W291L |
probably benign |
Het |
| Ttll3 |
G |
A |
6: 113,376,657 (GRCm39) |
V345I |
possibly damaging |
Het |
| Ttn |
A |
G |
2: 76,565,046 (GRCm39) |
Y28394H |
probably damaging |
Het |
| Usp45 |
A |
G |
4: 21,832,201 (GRCm39) |
Y684C |
probably damaging |
Het |
| Vdr |
A |
G |
15: 97,765,089 (GRCm39) |
S217P |
probably benign |
Het |
| Xpot |
A |
G |
10: 121,447,580 (GRCm39) |
L105P |
probably damaging |
Het |
| Zan |
A |
G |
5: 137,464,206 (GRCm39) |
I533T |
probably damaging |
Het |
| Zbtb8a |
T |
C |
4: 129,248,059 (GRCm39) |
E404G |
probably benign |
Het |
| Zfp451 |
A |
T |
1: 33,815,562 (GRCm39) |
F796Y |
probably damaging |
Het |
|
| Other mutations in Zfp106 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00330:Zfp106
|
APN |
2 |
120,369,978 (GRCm39) |
missense |
probably benign |
0.45 |
|
IGL00816:Zfp106
|
APN |
2 |
120,357,329 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL00822:Zfp106
|
APN |
2 |
120,344,641 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00848:Zfp106
|
APN |
2 |
120,343,208 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01293:Zfp106
|
APN |
2 |
120,365,516 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL01323:Zfp106
|
APN |
2 |
120,354,945 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
IGL01662:Zfp106
|
APN |
2 |
120,354,034 (GRCm39) |
missense |
probably benign |
0.17 |
|
IGL01683:Zfp106
|
APN |
2 |
120,355,036 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01809:Zfp106
|
APN |
2 |
120,364,152 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01958:Zfp106
|
APN |
2 |
120,365,288 (GRCm39) |
missense |
probably benign |
0.26 |
|
IGL01960:Zfp106
|
APN |
2 |
120,369,803 (GRCm39) |
missense |
probably benign |
0.08 |
|
IGL01960:Zfp106
|
APN |
2 |
120,354,524 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02168:Zfp106
|
APN |
2 |
120,364,712 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL02623:Zfp106
|
APN |
2 |
120,376,395 (GRCm39) |
splice site |
probably null |
|
|
IGL02798:Zfp106
|
APN |
2 |
120,340,991 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02828:Zfp106
|
APN |
2 |
120,362,178 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
IGL03022:Zfp106
|
APN |
2 |
120,359,120 (GRCm39) |
splice site |
probably benign |
|
|
IGL03308:Zfp106
|
APN |
2 |
120,354,505 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03324:Zfp106
|
APN |
2 |
120,365,868 (GRCm39) |
missense |
probably benign |
0.01 |
|
lepton
|
UTSW |
2 |
120,362,585 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Proton
|
UTSW |
2 |
120,341,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
quark
|
UTSW |
2 |
120,365,541 (GRCm39) |
nonsense |
probably null |
|
|
R0040_zfp106_031
|
UTSW |
2 |
120,362,094 (GRCm39) |
missense |
probably damaging |
1.00 |
|
string
|
UTSW |
2 |
120,364,075 (GRCm39) |
missense |
probably damaging |
0.96 |
|
theory
|
UTSW |
2 |
120,364,158 (GRCm39) |
nonsense |
probably null |
|
|
R0040:Zfp106
|
UTSW |
2 |
120,362,094 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0040:Zfp106
|
UTSW |
2 |
120,362,094 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0135:Zfp106
|
UTSW |
2 |
120,350,968 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0180:Zfp106
|
UTSW |
2 |
120,364,356 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0387:Zfp106
|
UTSW |
2 |
120,358,953 (GRCm39) |
splice site |
probably null |
|
|
R0558:Zfp106
|
UTSW |
2 |
120,362,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0680:Zfp106
|
UTSW |
2 |
120,357,497 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0729:Zfp106
|
UTSW |
2 |
120,385,729 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0828:Zfp106
|
UTSW |
2 |
120,366,084 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1124:Zfp106
|
UTSW |
2 |
120,365,195 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1147:Zfp106
|
UTSW |
2 |
120,351,017 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1147:Zfp106
|
UTSW |
2 |
120,351,017 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1226:Zfp106
|
UTSW |
2 |
120,354,560 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1239:Zfp106
|
UTSW |
2 |
120,364,075 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1634:Zfp106
|
UTSW |
2 |
120,364,158 (GRCm39) |
nonsense |
probably null |
|
|
R1754:Zfp106
|
UTSW |
2 |
120,364,245 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1754:Zfp106
|
UTSW |
2 |
120,364,244 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1755:Zfp106
|
UTSW |
2 |
120,365,656 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1763:Zfp106
|
UTSW |
2 |
120,350,909 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1875:Zfp106
|
UTSW |
2 |
120,344,096 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1903:Zfp106
|
UTSW |
2 |
120,357,329 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1932:Zfp106
|
UTSW |
2 |
120,362,162 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R2070:Zfp106
|
UTSW |
2 |
120,354,010 (GRCm39) |
missense |
probably benign |
0.11 |
|
R2301:Zfp106
|
UTSW |
2 |
120,366,131 (GRCm39) |
missense |
probably benign |
0.04 |
|
R3429:Zfp106
|
UTSW |
2 |
120,357,544 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3720:Zfp106
|
UTSW |
2 |
120,365,080 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3875:Zfp106
|
UTSW |
2 |
120,365,094 (GRCm39) |
missense |
probably benign |
0.08 |
|
R3881:Zfp106
|
UTSW |
2 |
120,362,630 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3921:Zfp106
|
UTSW |
2 |
120,364,097 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3923:Zfp106
|
UTSW |
2 |
120,365,337 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4087:Zfp106
|
UTSW |
2 |
120,357,380 (GRCm39) |
splice site |
probably null |
|
|
R4678:Zfp106
|
UTSW |
2 |
120,364,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4965:Zfp106
|
UTSW |
2 |
120,364,400 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5011:Zfp106
|
UTSW |
2 |
120,341,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5013:Zfp106
|
UTSW |
2 |
120,341,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5151:Zfp106
|
UTSW |
2 |
120,365,208 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5227:Zfp106
|
UTSW |
2 |
120,354,449 (GRCm39) |
missense |
probably benign |
0.11 |
|
R5328:Zfp106
|
UTSW |
2 |
120,350,898 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R5403:Zfp106
|
UTSW |
2 |
120,365,262 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5624:Zfp106
|
UTSW |
2 |
120,362,438 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5686:Zfp106
|
UTSW |
2 |
120,363,988 (GRCm39) |
splice site |
probably null |
|
|
R5691:Zfp106
|
UTSW |
2 |
120,354,952 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5852:Zfp106
|
UTSW |
2 |
120,346,487 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6032:Zfp106
|
UTSW |
2 |
120,365,874 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6032:Zfp106
|
UTSW |
2 |
120,365,874 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6298:Zfp106
|
UTSW |
2 |
120,353,185 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6409:Zfp106
|
UTSW |
2 |
120,362,585 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6505:Zfp106
|
UTSW |
2 |
120,364,983 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6598:Zfp106
|
UTSW |
2 |
120,365,541 (GRCm39) |
nonsense |
probably null |
|
|
R6765:Zfp106
|
UTSW |
2 |
120,369,935 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7013:Zfp106
|
UTSW |
2 |
120,362,113 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7453:Zfp106
|
UTSW |
2 |
120,376,400 (GRCm39) |
splice site |
probably null |
|
|
R7453:Zfp106
|
UTSW |
2 |
120,341,008 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7643:Zfp106
|
UTSW |
2 |
120,343,215 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7829:Zfp106
|
UTSW |
2 |
120,354,538 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7897:Zfp106
|
UTSW |
2 |
120,366,096 (GRCm39) |
nonsense |
probably null |
|
|
R7909:Zfp106
|
UTSW |
2 |
120,344,700 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8054:Zfp106
|
UTSW |
2 |
120,355,000 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R8124:Zfp106
|
UTSW |
2 |
120,354,812 (GRCm39) |
missense |
probably benign |
0.44 |
|
R8203:Zfp106
|
UTSW |
2 |
120,349,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8350:Zfp106
|
UTSW |
2 |
120,366,099 (GRCm39) |
missense |
|
|
|
R8450:Zfp106
|
UTSW |
2 |
120,366,099 (GRCm39) |
missense |
|
|
|
R8698:Zfp106
|
UTSW |
2 |
120,354,600 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8985:Zfp106
|
UTSW |
2 |
120,366,077 (GRCm39) |
missense |
|
|
|
R9015:Zfp106
|
UTSW |
2 |
120,364,019 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9142:Zfp106
|
UTSW |
2 |
120,350,935 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9154:Zfp106
|
UTSW |
2 |
120,364,812 (GRCm39) |
nonsense |
probably null |
|
|
R9175:Zfp106
|
UTSW |
2 |
120,353,197 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9529:Zfp106
|
UTSW |
2 |
120,351,007 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9572:Zfp106
|
UTSW |
2 |
120,349,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9581:Zfp106
|
UTSW |
2 |
120,365,807 (GRCm39) |
missense |
|
|
|
RF008:Zfp106
|
UTSW |
2 |
120,355,026 (GRCm39) |
small deletion |
probably benign |
|
|
RF025:Zfp106
|
UTSW |
2 |
120,355,026 (GRCm39) |
small deletion |
probably benign |
|
|
X0025:Zfp106
|
UTSW |
2 |
120,365,297 (GRCm39) |
missense |
probably benign |
|
|
Z1088:Zfp106
|
UTSW |
2 |
120,360,971 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTGCTGCACAAAGCTCTAGAGG -3'
(R):5'- ACTGTGGCCATCTGCATAC -3'
Sequencing Primer
(F):5'- TCCTCAGGACAGAGAAGTTGTCTAC -3'
(R):5'- TGCATACAGAGTCTTTCAGAGGC -3'
|
| Posted On |
2021-11-19 |
Incidental Mutation