Mutagenetix > Incidental Mutation

Incidental Mutation 'R9496:Hmcn1'

717203

Institutional Source

Beutler Lab

Gene Symbol

Hmcn1

Ensembl Gene

ENSMUSG00000066842

Gene Name

hemicentin 1

Synonyms

EG545370, LOC240793

MMRRC Submission

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R9496 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

150438275-150869186 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 150579971 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Glycine at position 1922 (D1922G)

Ref Sequence

ENSEMBL: ENSMUSP00000074340 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000074783] [ENSMUST00000137197]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000074783
AA Change: D1922G

PolyPhen 2 Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)

SMART Domains

Protein: ENSMUSP00000074340
Gene: ENSMUSG00000066842
AA Change: D1922G

Domain	Start	End	E-Value	Type
signal peptide	1	21	N/A	INTRINSIC
VWA	39	213	3e-1	SMART
IG_like	445	506	1.13e0	SMART
IGc2	532	598	2.32e-8	SMART
IGc2	624	688	1.24e-8	SMART
IGc2	714	779	7.52e-8	SMART
IGc2	805	874	2.19e-9	SMART
IGc2	902	967	5.15e-15	SMART
IGc2	993	1058	1.28e-10	SMART
IGc2	1092	1157	1.69e-10	SMART
IGc2	1183	1247	1.09e-13	SMART
IGc2	1278	1344	6.49e-12	SMART
IGc2	1372	1437	5.2e-11	SMART
IGc2	1465	1531	1.34e-13	SMART
IGc2	1559	1624	6.25e-14	SMART
IGc2	1653	1718	4.06e-13	SMART
IGc2	1746	1811	4.12e-14	SMART
IGc2	1838	1904	5.92e-15	SMART
IGc2	1932	1997	7.69e-14	SMART
IGc2	2023	2089	3.3e-13	SMART
IGc2	2115	2180	5e-13	SMART
IGc2	2208	2275	1.32e-12	SMART
IGc2	2304	2369	2.91e-14	SMART
IGc2	2398	2463	4e-12	SMART
IGc2	2491	2556	1.94e-19	SMART
IGc2	2587	2652	2.54e-14	SMART
IGc2	2686	2751	7.57e-13	SMART
IGc2	2789	2854	4.88e-16	SMART
IGc2	2884	2949	2.7e-9	SMART
IGc2	2976	3041	1.47e-10	SMART
IGc2	3071	3136	2.24e-15	SMART
IGc2	3163	3230	8.83e-14	SMART
IGc2	3258	3325	9.76e-16	SMART
IGc2	3354	3419	1.54e-13	SMART
IGc2	3447	3512	4.35e-13	SMART
IGc2	3540	3605	2e-12	SMART
IGc2	3633	3698	7.69e-14	SMART
IGc2	3724	3789	1.92e-14	SMART
IGc2	3815	3882	2.58e-6	SMART
IGc2	3908	3973	6.4e-11	SMART
IGc2	3999	4064	2.78e-11	SMART
IGc2	4090	4154	1.74e-12	SMART
low complexity region	4155	4160	N/A	INTRINSIC
IGc2	4180	4245	3.35e-14	SMART
IGc2	4271	4334	8.12e-13	SMART
IGc2	4361	4425	1.79e-14	SMART
IGc2	4451	4515	1.06e-11	SMART
TSP1	4531	4583	4.72e-15	SMART
TSP1	4588	4640	2.39e-16	SMART
TSP1	4645	4697	1.67e-15	SMART
TSP1	4702	4754	2.2e-15	SMART
TSP1	4759	4811	2.77e-12	SMART
TSP1	4816	4868	2.67e-14	SMART
Pfam:G2F	4869	5051	1.5e-57	PFAM
EGF_CA	5106	5145	4.38e-11	SMART
EGF_CA	5146	5190	4.49e-8	SMART
EGF_CA	5191	5228	2.38e-12	SMART
EGF_CA	5229	5270	6.8e-8	SMART
EGF_CA	5271	5313	3.51e-10	SMART
EGF_CA	5314	5354	4.32e-10	SMART
low complexity region	5384	5400	N/A	INTRINSIC
low complexity region	5401	5412	N/A	INTRINSIC
EGF_CA	5431	5470	2.78e-13	SMART
EGF	5474	5516	1.44e1	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000137197
AA Change: D1922G

PolyPhen 2 Score 0.432 (Sensitivity: 0.89; Specificity: 0.90)

SMART Domains

Protein: ENSMUSP00000121500
Gene: ENSMUSG00000066842
AA Change: D1922G

Domain	Start	End	E-Value	Type
signal peptide	1	21	N/A	INTRINSIC
VWA	39	213	3e-1	SMART
IG_like	445	506	1.13e0	SMART
IGc2	532	598	2.32e-8	SMART
IGc2	624	688	1.24e-8	SMART
IGc2	714	779	7.52e-8	SMART
IGc2	805	874	2.19e-9	SMART
IGc2	902	967	5.15e-15	SMART
IGc2	993	1058	1.28e-10	SMART
IGc2	1092	1157	1.69e-10	SMART
IGc2	1183	1247	1.09e-13	SMART
IGc2	1278	1344	6.49e-12	SMART
IGc2	1372	1437	5.2e-11	SMART
IGc2	1465	1531	1.34e-13	SMART
IGc2	1559	1624	6.25e-14	SMART
IGc2	1653	1718	4.06e-13	SMART
IGc2	1746	1811	4.12e-14	SMART
IGc2	1838	1904	5.92e-15	SMART
IGc2	1932	1997	7.69e-14	SMART
IGc2	2023	2089	3.3e-13	SMART
IGc2	2115	2180	5e-13	SMART
IGc2	2208	2275	1.32e-12	SMART
IGc2	2304	2369	2.91e-14	SMART
IGc2	2398	2463	4e-12	SMART
IGc2	2491	2556	1.94e-19	SMART
IGc2	2587	2652	2.54e-14	SMART
IGc2	2686	2751	7.57e-13	SMART
IGc2	2789	2854	4.88e-16	SMART
IGc2	2884	2949	2.7e-9	SMART
IGc2	2976	3041	1.47e-10	SMART
IGc2	3071	3136	2.24e-15	SMART
IGc2	3163	3230	8.83e-14	SMART
IGc2	3258	3325	9.76e-16	SMART
IGc2	3354	3419	1.54e-13	SMART
IGc2	3447	3512	4.35e-13	SMART
IGc2	3540	3605	2e-12	SMART
IGc2	3633	3698	7.69e-14	SMART
IGc2	3724	3789	1.92e-14	SMART
IGc2	3815	3882	2.58e-6	SMART
IGc2	3908	3973	6.4e-11	SMART
IGc2	3999	4064	2.78e-11	SMART
IGc2	4090	4154	1.74e-12	SMART
low complexity region	4155	4160	N/A	INTRINSIC
IGc2	4180	4245	3.35e-14	SMART
IGc2	4271	4334	8.12e-13	SMART
IGc2	4361	4425	1.79e-14	SMART
IGc2	4451	4515	1.06e-11	SMART
TSP1	4531	4583	4.72e-15	SMART
TSP1	4588	4640	2.39e-16	SMART
TSP1	4645	4697	1.67e-15	SMART
TSP1	4702	4754	2.2e-15	SMART
TSP1	4759	4811	2.77e-12	SMART
TSP1	4816	4868	2.67e-14	SMART
PDB:1GL4\|A	4869	5082	3e-6	PDB
SCOP:d1gl4a1	4869	5082	3e-79	SMART
EGF_CA	5106	5145	4.38e-11	SMART
EGF_CA	5146	5190	4.49e-8	SMART
EGF_CA	5191	5228	2.38e-12	SMART
EGF_CA	5229	5270	6.8e-8	SMART
EGF_CA	5271	5313	3.51e-10	SMART
EGF_CA	5314	5353	2.78e-13	SMART
EGF	5357	5399	1.44e1	SMART

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.7%
20x: 99.1%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a large extracellular member of the immunoglobulin superfamily. A similar protein in C. elegans forms long, fine tracks at specific extracellular sites that are involved in many processes such as stabilization of the germline syncytium, anchorage of mechanosensory neurons to the epidermis, and organization of hemidesmosomes in the epidermis. Mutations in this gene may be associated with age-related macular degeneration. [provided by RefSeq, Jul 2008]

Allele List at MGI

All alleles(4) : Targeted(3) Gene trapped(1)

Other mutations in this stock

Total: 52 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Atg2a	A	T	19: 6,310,022 (GRCm39)	Q1735L	possibly damaging	Het
Brpf3	A	G	17: 29,040,453 (GRCm39)	D958G	probably benign	Het
Cacna1g	A	G	11: 94,356,711 (GRCm39)	F142L	probably benign	Het
Calcoco1	C	T	15: 102,619,876 (GRCm39)	A303T	probably benign	Het
Chat	C	A	14: 32,148,119 (GRCm39)	C306F	probably benign	Het
Ciita	T	G	16: 10,298,009 (GRCm39)	M1R	probably null	Het
Ckap2l	A	C	2: 129,112,595 (GRCm39)	S638A	probably benign	Het
Coro1c	C	T	5: 113,983,337 (GRCm39)	G397D	probably benign	Het
Cyb5r2	A	G	7: 107,353,954 (GRCm39)	V72A	probably damaging	Het
Cyp2t4	G	A	7: 26,854,717 (GRCm39)	V66M	possibly damaging	Het
Dcbld2	A	G	16: 58,271,164 (GRCm39)	T314A	probably benign	Het
Dcun1d4	T	G	5: 73,668,272 (GRCm39)	H37Q	probably damaging	Het
Dgkd	T	A	1: 87,857,464 (GRCm39)	S725R	probably benign	Het
Dhx29	T	C	13: 113,089,460 (GRCm39)	Y744H	probably damaging	Het
Ect2l	T	C	10: 18,004,885 (GRCm39)	N916S	probably damaging	Het
Ep400	T	C	5: 110,855,853 (GRCm39)	K1287E	unknown	Het
Epo	C	T	5: 137,482,401 (GRCm39)	V89I	probably benign	Het
Fbxw15	A	T	9: 109,397,291 (GRCm39)	I3N	probably benign	Het
Fcgr3	A	C	1: 170,879,386 (GRCm39)	Y219D	possibly damaging	Het
Fign	A	T	2: 63,809,253 (GRCm39)	C672*	probably null	Het
Fsip2	A	T	2: 82,793,062 (GRCm39)	R406S	probably benign	Het
Gli2	A	G	1: 118,764,425 (GRCm39)	V1242A	probably benign	Het
Gm10577	C	T	4: 100,877,745 (GRCm39)	C50Y	unknown	Het
Gm11568	GCTGCTGCCAGCCCTGCTGCCAGCCC	GCTGCTGCCAGCCCTGCTGCCAGCCCTGCTGCCAGCCC	11: 99,749,044 (GRCm39)		probably benign	Het
Grid1	T	C	14: 35,291,571 (GRCm39)	L826P	probably damaging	Het
Itga2b	C	T	11: 102,358,629 (GRCm39)	C96Y	probably damaging	Het
Itih2	A	T	2: 10,106,984 (GRCm39)	I670N	probably benign	Het
Lypla1	A	T	1: 4,898,813 (GRCm39)		probably benign	Het
Mettl16	T	C	11: 74,707,696 (GRCm39)	S337P	possibly damaging	Het
Myh11	G	A	16: 14,048,616 (GRCm39)	Q564*	probably null	Het
Myrf	A	G	19: 10,193,840 (GRCm39)	F529L	probably benign	Het
Nell2	T	G	15: 95,194,097 (GRCm39)	I539L	probably benign	Het
Nfxl1	A	T	5: 72,685,502 (GRCm39)	V646E	possibly damaging	Het
Nin	T	C	12: 70,102,762 (GRCm39)	T289A		Het
Obsl1	C	T	1: 75,467,484 (GRCm39)	C1430Y	probably damaging	Het
Otog	T	C	7: 45,890,505 (GRCm39)	L18P	unknown	Het
Pkd1l1	C	A	11: 8,783,773 (GRCm39)		probably null	Het
Pum1	T	C	4: 130,446,664 (GRCm39)		probably null	Het
Rhbdl1	A	T	17: 26,055,371 (GRCm39)		probably null	Het
Rmdn2	T	A	17: 79,975,425 (GRCm39)	L305I	possibly damaging	Het
Scn3a	A	G	2: 65,312,493 (GRCm39)		probably null	Het
Shtn1	G	T	19: 58,963,457 (GRCm39)	S619R	probably damaging	Het
Smpd1	G	A	7: 105,205,202 (GRCm39)		probably null	Het
Tepsin	A	G	11: 119,982,357 (GRCm39)	L571S	probably damaging	Het
Tm7sf3	C	T	6: 146,525,179 (GRCm39)	D89N	possibly damaging	Het
Tssk5	T	C	15: 76,258,856 (GRCm39)	D10G	probably benign	Het
Usp39	A	G	6: 72,302,759 (GRCm39)	Y432H	probably benign	Het
Vmn2r97	T	A	17: 19,149,227 (GRCm39)	V205D	probably damaging	Het
Vwa8	T	C	14: 79,258,122 (GRCm39)	V757A	probably benign	Het
Zc2hc1b	A	T	10: 13,044,540 (GRCm39)	F41Y	probably damaging	Het
Zfp1007	A	G	5: 109,823,924 (GRCm39)	S509P	probably damaging	Het
Zfp114	A	T	7: 23,880,463 (GRCm39)	S271C	possibly damaging	Het

Other mutations in Hmcn1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00417:Hmcn1	APN	1	150,553,029 (GRCm39)	missense	probably benign
IGL00571:Hmcn1	APN	1	150,514,750 (GRCm39)	missense	probably benign	0.05
IGL00726:Hmcn1	APN	1	150,682,117 (GRCm39)	critical splice donor site	probably null
IGL00802:Hmcn1	APN	1	150,540,687 (GRCm39)	missense	probably benign	0.19
IGL00824:Hmcn1	APN	1	150,532,485 (GRCm39)	missense	probably damaging	1.00
IGL00834:Hmcn1	APN	1	150,506,091 (GRCm39)	missense	probably benign	0.00
IGL00843:Hmcn1	APN	1	150,486,464 (GRCm39)	missense	possibly damaging	0.95
IGL00845:Hmcn1	APN	1	150,480,757 (GRCm39)	missense	probably damaging	0.98
IGL00851:Hmcn1	APN	1	150,458,052 (GRCm39)	missense	probably benign	0.02
IGL00909:Hmcn1	APN	1	150,514,620 (GRCm39)	missense	probably benign	0.12
IGL01074:Hmcn1	APN	1	150,502,784 (GRCm39)	missense	possibly damaging	0.82
IGL01112:Hmcn1	APN	1	150,508,303 (GRCm39)	splice site	probably benign
IGL01304:Hmcn1	APN	1	150,498,675 (GRCm39)	missense	probably damaging	0.99
IGL01307:Hmcn1	APN	1	150,620,752 (GRCm39)	missense	possibly damaging	0.84
IGL01318:Hmcn1	APN	1	150,594,991 (GRCm39)	missense	probably damaging	1.00
IGL01403:Hmcn1	APN	1	150,468,848 (GRCm39)	missense	probably damaging	1.00
IGL01417:Hmcn1	APN	1	150,734,990 (GRCm39)	missense	probably damaging	1.00
IGL01503:Hmcn1	APN	1	150,480,823 (GRCm39)	missense	probably benign	0.38
IGL01509:Hmcn1	APN	1	150,485,382 (GRCm39)	missense	probably damaging	1.00
IGL01550:Hmcn1	APN	1	150,474,148 (GRCm39)	missense	probably damaging	1.00
IGL01601:Hmcn1	APN	1	150,503,164 (GRCm39)	missense	probably benign	0.01
IGL01617:Hmcn1	APN	1	150,547,783 (GRCm39)	missense	probably benign	0.05
IGL01636:Hmcn1	APN	1	150,455,984 (GRCm39)	missense	probably damaging	1.00
IGL01662:Hmcn1	APN	1	150,613,050 (GRCm39)	missense	possibly damaging	0.46
IGL01693:Hmcn1	APN	1	150,459,031 (GRCm39)	missense	probably damaging	1.00
IGL01723:Hmcn1	APN	1	150,620,711 (GRCm39)	missense	probably benign	0.01
IGL01776:Hmcn1	APN	1	150,547,789 (GRCm39)	missense	possibly damaging	0.70
IGL01783:Hmcn1	APN	1	150,491,051 (GRCm39)	missense	possibly damaging	0.60
IGL01789:Hmcn1	APN	1	150,566,352 (GRCm39)	missense	probably damaging	1.00
IGL01900:Hmcn1	APN	1	150,618,011 (GRCm39)	splice site	probably benign
IGL01906:Hmcn1	APN	1	150,543,638 (GRCm39)	missense	probably benign	0.01
IGL01947:Hmcn1	APN	1	150,608,643 (GRCm39)	missense	possibly damaging	0.93
IGL01958:Hmcn1	APN	1	150,479,622 (GRCm39)	missense	probably benign	0.01
IGL02002:Hmcn1	APN	1	150,491,049 (GRCm39)	missense	probably damaging	1.00
IGL02058:Hmcn1	APN	1	150,579,932 (GRCm39)	missense	probably benign	0.02
IGL02115:Hmcn1	APN	1	150,506,479 (GRCm39)	missense	probably damaging	1.00
IGL02127:Hmcn1	APN	1	150,598,358 (GRCm39)	missense	probably benign
IGL02155:Hmcn1	APN	1	150,439,349 (GRCm39)	missense	probably damaging	1.00
IGL02222:Hmcn1	APN	1	150,682,152 (GRCm39)	missense	probably benign	0.05
IGL02293:Hmcn1	APN	1	150,540,666 (GRCm39)	missense	probably damaging	0.97
IGL02398:Hmcn1	APN	1	150,678,648 (GRCm39)	missense	possibly damaging	0.78
IGL02420:Hmcn1	APN	1	150,598,175 (GRCm39)	missense	probably damaging	1.00
IGL02553:Hmcn1	APN	1	150,868,774 (GRCm39)	missense	probably benign	0.12
IGL02561:Hmcn1	APN	1	150,685,477 (GRCm39)	missense	probably benign	0.32
IGL02569:Hmcn1	APN	1	150,573,244 (GRCm39)	missense	probably benign	0.01
IGL02607:Hmcn1	APN	1	150,620,746 (GRCm39)	missense	possibly damaging	0.88
IGL02676:Hmcn1	APN	1	150,494,760 (GRCm39)	missense	probably benign	0.01
IGL02725:Hmcn1	APN	1	150,480,654 (GRCm39)	missense	possibly damaging	0.92
IGL02726:Hmcn1	APN	1	150,532,445 (GRCm39)	nonsense	probably null
IGL02735:Hmcn1	APN	1	150,522,583 (GRCm39)	missense	probably benign	0.02
IGL02737:Hmcn1	APN	1	150,439,579 (GRCm39)	missense	probably damaging	1.00
IGL02892:Hmcn1	APN	1	150,551,725 (GRCm39)	critical splice donor site	probably null
IGL02927:Hmcn1	APN	1	150,453,029 (GRCm39)	missense	probably damaging	1.00
IGL02931:Hmcn1	APN	1	150,532,958 (GRCm39)	missense	probably benign	0.37
IGL02936:Hmcn1	APN	1	150,573,273 (GRCm39)	missense	probably damaging	0.98
IGL02985:Hmcn1	APN	1	150,547,668 (GRCm39)	missense	probably damaging	1.00
IGL03027:Hmcn1	APN	1	150,684,290 (GRCm39)	missense	probably benign
IGL03195:Hmcn1	APN	1	150,678,660 (GRCm39)	missense	probably benign	0.06
IGL03217:Hmcn1	APN	1	150,619,418 (GRCm39)	missense	possibly damaging	0.58
IGL03232:Hmcn1	APN	1	150,646,103 (GRCm39)	splice site	probably benign
IGL03268:Hmcn1	APN	1	150,648,261 (GRCm39)	missense	probably damaging	1.00
IGL03271:Hmcn1	APN	1	150,474,175 (GRCm39)	missense	possibly damaging	0.92
IGL03304:Hmcn1	APN	1	150,505,982 (GRCm39)	missense	probably damaging	0.97
IGL03329:Hmcn1	APN	1	150,608,661 (GRCm39)	missense	probably damaging	1.00
IGL03339:Hmcn1	APN	1	150,577,720 (GRCm39)	missense	probably benign	0.04
IGL03368:Hmcn1	APN	1	150,539,623 (GRCm39)	missense	probably damaging	1.00
Backbone	UTSW	1	150,498,745 (GRCm39)	missense	probably benign	0.09
Cambrian	UTSW	1	150,608,597 (GRCm39)	missense	probably damaging	1.00
chordate	UTSW	1	150,462,766 (GRCm39)	missense	probably benign	0.00
Justamere	UTSW	1	150,464,008 (GRCm39)	missense	probably damaging	1.00
Lancelet	UTSW	1	150,551,291 (GRCm39)	missense	probably benign	0.00
notochord	UTSW	1	150,646,044 (GRCm39)	missense	probably benign	0.00
wippoorwill	UTSW	1	150,608,697 (GRCm39)	missense	probably damaging	1.00
BB004:Hmcn1	UTSW	1	150,485,526 (GRCm39)	missense	probably damaging	1.00
BB014:Hmcn1	UTSW	1	150,485,526 (GRCm39)	missense	probably damaging	1.00
IGL02991:Hmcn1	UTSW	1	150,614,409 (GRCm39)	missense	possibly damaging	0.56
P0017:Hmcn1	UTSW	1	150,596,440 (GRCm39)	missense	possibly damaging	0.49
PIT1430001:Hmcn1	UTSW	1	150,684,488 (GRCm39)	missense	probably benign	0.00
PIT4514001:Hmcn1	UTSW	1	150,545,238 (GRCm39)	missense	possibly damaging	0.93
R0006:Hmcn1	UTSW	1	150,684,427 (GRCm39)	missense	probably damaging	0.99
R0018:Hmcn1	UTSW	1	150,528,302 (GRCm39)	missense	probably benign	0.16
R0052:Hmcn1	UTSW	1	150,553,157 (GRCm39)	missense	probably damaging	1.00
R0107:Hmcn1	UTSW	1	150,462,766 (GRCm39)	missense	probably benign	0.00
R0115:Hmcn1	UTSW	1	150,684,398 (GRCm39)	missense	possibly damaging	0.88
R0149:Hmcn1	UTSW	1	150,553,075 (GRCm39)	missense	probably benign	0.00
R0152:Hmcn1	UTSW	1	150,539,630 (GRCm39)	missense	probably benign	0.01
R0381:Hmcn1	UTSW	1	150,479,562 (GRCm39)	missense	probably damaging	1.00
R0398:Hmcn1	UTSW	1	150,674,565 (GRCm39)	missense	possibly damaging	0.83
R0414:Hmcn1	UTSW	1	150,591,573 (GRCm39)	missense	possibly damaging	0.72
R0494:Hmcn1	UTSW	1	150,608,543 (GRCm39)	splice site	probably benign
R0503:Hmcn1	UTSW	1	150,735,003 (GRCm39)	missense	probably damaging	1.00
R0504:Hmcn1	UTSW	1	150,752,170 (GRCm39)	splice site	probably benign
R0506:Hmcn1	UTSW	1	150,618,092 (GRCm39)	missense	possibly damaging	0.69
R0554:Hmcn1	UTSW	1	150,594,868 (GRCm39)	missense	probably benign	0.34
R0576:Hmcn1	UTSW	1	150,525,768 (GRCm39)	nonsense	probably null
R0599:Hmcn1	UTSW	1	150,485,552 (GRCm39)	missense	possibly damaging	0.91
R0605:Hmcn1	UTSW	1	150,533,127 (GRCm39)	critical splice donor site	probably null
R0607:Hmcn1	UTSW	1	150,514,651 (GRCm39)	missense	probably benign	0.01
R0620:Hmcn1	UTSW	1	150,469,767 (GRCm39)	missense	probably benign	0.04
R0626:Hmcn1	UTSW	1	150,674,470 (GRCm39)	splice site	probably null
R0699:Hmcn1	UTSW	1	150,695,161 (GRCm39)	missense	probably damaging	1.00
R0765:Hmcn1	UTSW	1	150,684,538 (GRCm39)	missense	probably damaging	1.00
R0782:Hmcn1	UTSW	1	150,629,416 (GRCm39)	missense	possibly damaging	0.82
R0783:Hmcn1	UTSW	1	150,525,824 (GRCm39)	missense	probably damaging	1.00
R0841:Hmcn1	UTSW	1	150,555,358 (GRCm39)	splice site	probably null
R0975:Hmcn1	UTSW	1	150,453,128 (GRCm39)	missense	probably benign	0.00
R1070:Hmcn1	UTSW	1	150,565,341 (GRCm39)	missense	probably damaging	0.98
R1118:Hmcn1	UTSW	1	150,494,679 (GRCm39)	missense	possibly damaging	0.56
R1119:Hmcn1	UTSW	1	150,494,679 (GRCm39)	missense	possibly damaging	0.56
R1145:Hmcn1	UTSW	1	150,555,358 (GRCm39)	splice site	probably null
R1145:Hmcn1	UTSW	1	150,555,358 (GRCm39)	splice site	probably null
R1233:Hmcn1	UTSW	1	150,624,777 (GRCm39)	missense	probably benign
R1234:Hmcn1	UTSW	1	150,629,405 (GRCm39)	nonsense	probably null
R1291:Hmcn1	UTSW	1	150,623,942 (GRCm39)	missense	probably damaging	1.00
R1334:Hmcn1	UTSW	1	150,462,219 (GRCm39)	missense	possibly damaging	0.73
R1372:Hmcn1	UTSW	1	150,556,466 (GRCm39)	missense	probably benign	0.22
R1424:Hmcn1	UTSW	1	150,522,545 (GRCm39)	missense	probably benign	0.00
R1450:Hmcn1	UTSW	1	150,528,257 (GRCm39)	splice site	probably benign
R1458:Hmcn1	UTSW	1	150,485,451 (GRCm39)	missense	probably damaging	1.00
R1467:Hmcn1	UTSW	1	150,565,341 (GRCm39)	missense	probably damaging	0.98
R1467:Hmcn1	UTSW	1	150,565,341 (GRCm39)	missense	probably damaging	0.98
R1473:Hmcn1	UTSW	1	150,648,303 (GRCm39)	missense	probably benign	0.03
R1517:Hmcn1	UTSW	1	150,545,172 (GRCm39)	missense	probably damaging	1.00
R1527:Hmcn1	UTSW	1	150,649,554 (GRCm39)	missense	probably benign	0.00
R1557:Hmcn1	UTSW	1	150,610,283 (GRCm39)	missense	possibly damaging	0.86
R1576:Hmcn1	UTSW	1	150,532,992 (GRCm39)	missense	possibly damaging	0.77
R1617:Hmcn1	UTSW	1	150,620,778 (GRCm39)	missense	probably damaging	0.98
R1635:Hmcn1	UTSW	1	150,545,309 (GRCm39)	missense	probably benign	0.00
R1655:Hmcn1	UTSW	1	150,506,084 (GRCm39)	missense	probably benign	0.03
R1698:Hmcn1	UTSW	1	150,441,120 (GRCm39)	nonsense	probably null
R1710:Hmcn1	UTSW	1	150,551,735 (GRCm39)	missense	probably damaging	1.00
R1717:Hmcn1	UTSW	1	150,734,937 (GRCm39)	missense	probably damaging	1.00
R1753:Hmcn1	UTSW	1	150,462,219 (GRCm39)	missense	possibly damaging	0.73
R1756:Hmcn1	UTSW	1	150,474,781 (GRCm39)	missense	probably damaging	1.00
R1772:Hmcn1	UTSW	1	150,439,319 (GRCm39)	missense	probably damaging	0.99
R1793:Hmcn1	UTSW	1	150,624,834 (GRCm39)	missense	probably benign	0.01
R1794:Hmcn1	UTSW	1	150,502,903 (GRCm39)	missense	probably damaging	0.98
R1794:Hmcn1	UTSW	1	150,474,036 (GRCm39)	missense	probably benign	0.00
R1856:Hmcn1	UTSW	1	150,597,415 (GRCm39)	missense	probably benign	0.02
R1859:Hmcn1	UTSW	1	150,532,944 (GRCm39)	missense	probably damaging	1.00
R1862:Hmcn1	UTSW	1	150,514,651 (GRCm39)	missense	probably benign	0.01
R1865:Hmcn1	UTSW	1	150,479,563 (GRCm39)	missense	probably damaging	1.00
R1874:Hmcn1	UTSW	1	150,596,446 (GRCm39)	missense	probably damaging	1.00
R1880:Hmcn1	UTSW	1	150,514,651 (GRCm39)	missense	probably benign	0.01
R1881:Hmcn1	UTSW	1	150,514,651 (GRCm39)	missense	probably benign	0.01
R1886:Hmcn1	UTSW	1	150,453,046 (GRCm39)	missense	probably benign	0.02
R1888:Hmcn1	UTSW	1	150,695,251 (GRCm39)	missense	possibly damaging	0.82
R1888:Hmcn1	UTSW	1	150,695,251 (GRCm39)	missense	possibly damaging	0.82
R1899:Hmcn1	UTSW	1	150,533,202 (GRCm39)	missense	probably damaging	1.00
R1905:Hmcn1	UTSW	1	150,868,606 (GRCm39)	missense	probably damaging	1.00
R1912:Hmcn1	UTSW	1	150,480,633 (GRCm39)	missense	probably benign	0.28
R1959:Hmcn1	UTSW	1	150,525,427 (GRCm39)	missense	probably benign	0.00
R1960:Hmcn1	UTSW	1	150,553,127 (GRCm39)	missense	possibly damaging	0.72
R1960:Hmcn1	UTSW	1	150,551,742 (GRCm39)	missense	probably benign	0.00
R2001:Hmcn1	UTSW	1	150,614,364 (GRCm39)	missense	possibly damaging	0.81
R2011:Hmcn1	UTSW	1	150,553,085 (GRCm39)	missense	probably benign	0.01
R2075:Hmcn1	UTSW	1	150,453,074 (GRCm39)	missense	possibly damaging	0.86
R2136:Hmcn1	UTSW	1	150,509,410 (GRCm39)	missense	probably damaging	1.00
R2192:Hmcn1	UTSW	1	150,591,566 (GRCm39)	missense	probably damaging	0.97
R2267:Hmcn1	UTSW	1	150,474,761 (GRCm39)	missense	probably benign	0.00
R2268:Hmcn1	UTSW	1	150,500,349 (GRCm39)	splice site	probably benign
R2303:Hmcn1	UTSW	1	150,579,977 (GRCm39)	missense	probably damaging	1.00
R2330:Hmcn1	UTSW	1	150,528,429 (GRCm39)	splice site	probably benign
R2338:Hmcn1	UTSW	1	150,498,685 (GRCm39)	missense	possibly damaging	0.89
R2380:Hmcn1	UTSW	1	150,441,135 (GRCm39)	missense	probably benign	0.01
R2405:Hmcn1	UTSW	1	150,736,092 (GRCm39)	missense	probably damaging	1.00
R2443:Hmcn1	UTSW	1	150,474,783 (GRCm39)	missense	probably benign	0.01
R2496:Hmcn1	UTSW	1	150,490,972 (GRCm39)	missense	probably benign	0.01
R2504:Hmcn1	UTSW	1	150,562,618 (GRCm39)	nonsense	probably null
R2519:Hmcn1	UTSW	1	150,649,571 (GRCm39)	nonsense	probably null
R2520:Hmcn1	UTSW	1	150,619,398 (GRCm39)	missense	possibly damaging	0.72
R2679:Hmcn1	UTSW	1	150,528,326 (GRCm39)	missense	possibly damaging	0.67
R2831:Hmcn1	UTSW	1	150,506,403 (GRCm39)	critical splice donor site	probably null
R2847:Hmcn1	UTSW	1	150,439,350 (GRCm39)	nonsense	probably null
R2849:Hmcn1	UTSW	1	150,439,350 (GRCm39)	nonsense	probably null
R2869:Hmcn1	UTSW	1	150,614,467 (GRCm39)	missense	possibly damaging	0.95
R2869:Hmcn1	UTSW	1	150,614,467 (GRCm39)	missense	possibly damaging	0.95
R2871:Hmcn1	UTSW	1	150,614,467 (GRCm39)	missense	possibly damaging	0.95
R2871:Hmcn1	UTSW	1	150,614,467 (GRCm39)	missense	possibly damaging	0.95
R2872:Hmcn1	UTSW	1	150,614,467 (GRCm39)	missense	possibly damaging	0.95
R2872:Hmcn1	UTSW	1	150,614,467 (GRCm39)	missense	possibly damaging	0.95
R2873:Hmcn1	UTSW	1	150,614,467 (GRCm39)	missense	possibly damaging	0.95
R2897:Hmcn1	UTSW	1	150,678,624 (GRCm39)	missense	probably damaging	1.00
R2905:Hmcn1	UTSW	1	150,624,786 (GRCm39)	missense	probably damaging	1.00
R3498:Hmcn1	UTSW	1	150,480,853 (GRCm39)	missense	probably damaging	0.98
R3499:Hmcn1	UTSW	1	150,480,853 (GRCm39)	missense	probably damaging	0.98
R3724:Hmcn1	UTSW	1	150,565,269 (GRCm39)	missense	possibly damaging	0.82
R3765:Hmcn1	UTSW	1	150,620,776 (GRCm39)	missense	possibly damaging	0.72
R3778:Hmcn1	UTSW	1	150,678,575 (GRCm39)	missense	possibly damaging	0.95
R3790:Hmcn1	UTSW	1	150,498,745 (GRCm39)	missense	probably benign	0.09
R3796:Hmcn1	UTSW	1	150,462,169 (GRCm39)	missense	probably damaging	1.00
R3811:Hmcn1	UTSW	1	150,525,328 (GRCm39)	critical splice donor site	probably null
R3825:Hmcn1	UTSW	1	150,462,716 (GRCm39)	missense	probably benign	0.28
R3890:Hmcn1	UTSW	1	150,510,946 (GRCm39)	missense	probably damaging	1.00
R3891:Hmcn1	UTSW	1	150,510,946 (GRCm39)	missense	probably damaging	1.00
R3892:Hmcn1	UTSW	1	150,510,946 (GRCm39)	missense	probably damaging	1.00
R3918:Hmcn1	UTSW	1	150,566,361 (GRCm39)	missense	probably benign	0.00
R3964:Hmcn1	UTSW	1	150,449,320 (GRCm39)	missense	probably benign	0.00
R4005:Hmcn1	UTSW	1	150,598,204 (GRCm39)	missense	possibly damaging	0.88
R4026:Hmcn1	UTSW	1	150,598,120 (GRCm39)	missense	probably benign	0.03
R4037:Hmcn1	UTSW	1	150,648,253 (GRCm39)	missense	probably benign	0.00
R4088:Hmcn1	UTSW	1	150,578,967 (GRCm39)	missense	possibly damaging	0.58
R4096:Hmcn1	UTSW	1	150,534,259 (GRCm39)	missense	probably benign	0.20
R4169:Hmcn1	UTSW	1	150,471,750 (GRCm39)	splice site	probably null
R4441:Hmcn1	UTSW	1	150,533,210 (GRCm39)	missense	probably null
R4493:Hmcn1	UTSW	1	150,577,650 (GRCm39)	missense	probably damaging	1.00
R4501:Hmcn1	UTSW	1	150,509,417 (GRCm39)	missense	probably damaging	1.00
R4535:Hmcn1	UTSW	1	150,439,531 (GRCm39)	missense	probably damaging	0.99
R4576:Hmcn1	UTSW	1	150,610,238 (GRCm39)	missense	probably benign
R4601:Hmcn1	UTSW	1	150,614,396 (GRCm39)	missense	probably damaging	0.99
R4627:Hmcn1	UTSW	1	150,471,645 (GRCm39)	missense	probably benign	0.11
R4647:Hmcn1	UTSW	1	150,551,262 (GRCm39)	critical splice donor site	probably null
R4657:Hmcn1	UTSW	1	150,500,301 (GRCm39)	missense	probably damaging	1.00
R4717:Hmcn1	UTSW	1	150,494,816 (GRCm39)	missense	probably benign	0.00
R4721:Hmcn1	UTSW	1	150,648,322 (GRCm39)	splice site	probably null
R4724:Hmcn1	UTSW	1	150,570,584 (GRCm39)	splice site	probably null
R4737:Hmcn1	UTSW	1	150,565,346 (GRCm39)	missense	possibly damaging	0.90
R4744:Hmcn1	UTSW	1	150,453,363 (GRCm39)	missense	probably damaging	1.00
R4795:Hmcn1	UTSW	1	150,629,362 (GRCm39)	missense	probably benign	0.00
R4796:Hmcn1	UTSW	1	150,629,362 (GRCm39)	missense	probably benign	0.00
R4871:Hmcn1	UTSW	1	150,468,836 (GRCm39)	missense	probably benign	0.02
R4895:Hmcn1	UTSW	1	150,553,130 (GRCm39)	missense	probably benign	0.00
R4934:Hmcn1	UTSW	1	150,598,286 (GRCm39)	missense	probably damaging	1.00
R4953:Hmcn1	UTSW	1	150,752,111 (GRCm39)	intron	probably benign
R4968:Hmcn1	UTSW	1	150,533,221 (GRCm39)	missense	possibly damaging	0.67
R4974:Hmcn1	UTSW	1	150,695,200 (GRCm39)	missense	probably benign	0.01
R5024:Hmcn1	UTSW	1	150,556,439 (GRCm39)	missense	possibly damaging	0.65
R5031:Hmcn1	UTSW	1	150,464,008 (GRCm39)	missense	probably damaging	1.00
R5093:Hmcn1	UTSW	1	150,613,007 (GRCm39)	missense	probably benign	0.14
R5096:Hmcn1	UTSW	1	150,486,420 (GRCm39)	missense	probably damaging	1.00
R5185:Hmcn1	UTSW	1	150,532,492 (GRCm39)	missense	probably benign	0.03
R5228:Hmcn1	UTSW	1	150,522,452 (GRCm39)	missense	probably benign	0.00
R5260:Hmcn1	UTSW	1	150,471,612 (GRCm39)	missense	possibly damaging	0.65
R5264:Hmcn1	UTSW	1	150,555,265 (GRCm39)	missense	probably benign	0.01
R5282:Hmcn1	UTSW	1	150,458,047 (GRCm39)	missense	probably damaging	1.00
R5334:Hmcn1	UTSW	1	150,631,123 (GRCm39)	missense	probably damaging	0.99
R5346:Hmcn1	UTSW	1	150,498,995 (GRCm39)	missense	probably damaging	1.00
R5423:Hmcn1	UTSW	1	150,577,723 (GRCm39)	missense	probably damaging	1.00
R5484:Hmcn1	UTSW	1	150,551,291 (GRCm39)	missense	probably benign	0.00
R5491:Hmcn1	UTSW	1	150,485,576 (GRCm39)	splice site	probably null
R5531:Hmcn1	UTSW	1	150,619,539 (GRCm39)	missense	probably damaging	1.00
R5536:Hmcn1	UTSW	1	150,631,042 (GRCm39)	missense	probably benign	0.01
R5547:Hmcn1	UTSW	1	150,613,257 (GRCm39)	missense	possibly damaging	0.64
R5580:Hmcn1	UTSW	1	150,453,290 (GRCm39)	missense	probably benign	0.43
R5626:Hmcn1	UTSW	1	150,532,318 (GRCm39)	missense	probably damaging	1.00
R5657:Hmcn1	UTSW	1	150,534,313 (GRCm39)	missense	probably benign	0.02
R5677:Hmcn1	UTSW	1	150,485,529 (GRCm39)	missense	probably benign	0.00
R5718:Hmcn1	UTSW	1	150,566,351 (GRCm39)	nonsense	probably null
R5718:Hmcn1	UTSW	1	150,485,417 (GRCm39)	missense	probably damaging	1.00
R5723:Hmcn1	UTSW	1	150,570,600 (GRCm39)	missense	possibly damaging	0.95
R5739:Hmcn1	UTSW	1	150,634,225 (GRCm39)	splice site	probably null
R5739:Hmcn1	UTSW	1	150,684,448 (GRCm39)	missense	probably benign	0.45
R5751:Hmcn1	UTSW	1	150,449,305 (GRCm39)	missense	probably damaging	1.00
R5772:Hmcn1	UTSW	1	150,570,629 (GRCm39)	missense	possibly damaging	0.47
R5804:Hmcn1	UTSW	1	150,550,098 (GRCm39)	nonsense	probably null
R5809:Hmcn1	UTSW	1	150,525,358 (GRCm39)	missense	probably damaging	1.00
R5817:Hmcn1	UTSW	1	150,613,275 (GRCm39)	missense	possibly damaging	0.77
R5824:Hmcn1	UTSW	1	150,868,774 (GRCm39)	missense	probably benign	0.12
R5881:Hmcn1	UTSW	1	150,506,078 (GRCm39)	missense	probably damaging	0.99
R5928:Hmcn1	UTSW	1	150,474,648 (GRCm39)	missense	possibly damaging	0.64
R5929:Hmcn1	UTSW	1	150,453,047 (GRCm39)	nonsense	probably null
R5940:Hmcn1	UTSW	1	150,532,973 (GRCm39)	missense	probably benign	0.41
R5973:Hmcn1	UTSW	1	150,439,568 (GRCm39)	missense	probably damaging	1.00
R5997:Hmcn1	UTSW	1	150,579,924 (GRCm39)	missense	possibly damaging	0.74
R6027:Hmcn1	UTSW	1	150,678,646 (GRCm39)	missense	possibly damaging	0.79
R6029:Hmcn1	UTSW	1	150,508,188 (GRCm39)	missense	probably benign	0.13
R6056:Hmcn1	UTSW	1	150,539,660 (GRCm39)	missense	probably damaging	1.00
R6065:Hmcn1	UTSW	1	150,646,081 (GRCm39)	missense	probably benign	0.06
R6083:Hmcn1	UTSW	1	150,631,045 (GRCm39)	missense	probably damaging	1.00
R6083:Hmcn1	UTSW	1	150,631,044 (GRCm39)	missense	probably damaging	1.00
R6108:Hmcn1	UTSW	1	150,506,978 (GRCm39)	missense	possibly damaging	0.95
R6112:Hmcn1	UTSW	1	150,494,687 (GRCm39)	missense	probably damaging	1.00
R6140:Hmcn1	UTSW	1	150,608,597 (GRCm39)	missense	probably damaging	1.00
R6144:Hmcn1	UTSW	1	150,598,175 (GRCm39)	missense	probably damaging	1.00
R6152:Hmcn1	UTSW	1	150,441,176 (GRCm39)	missense	probably damaging	1.00
R6174:Hmcn1	UTSW	1	150,522,535 (GRCm39)	missense	probably benign	0.06
R6185:Hmcn1	UTSW	1	150,491,189 (GRCm39)	splice site	probably null
R6187:Hmcn1	UTSW	1	150,506,479 (GRCm39)	missense	probably damaging	1.00
R6276:Hmcn1	UTSW	1	150,614,432 (GRCm39)	missense	possibly damaging	0.69
R6278:Hmcn1	UTSW	1	150,573,170 (GRCm39)	critical splice donor site	probably null
R6427:Hmcn1	UTSW	1	150,573,227 (GRCm39)	missense	possibly damaging	0.85
R6431:Hmcn1	UTSW	1	150,620,711 (GRCm39)	missense	probably benign	0.01
R6441:Hmcn1	UTSW	1	150,578,967 (GRCm39)	missense	possibly damaging	0.58
R6451:Hmcn1	UTSW	1	150,868,670 (GRCm39)	missense	probably damaging	1.00
R6478:Hmcn1	UTSW	1	150,540,535 (GRCm39)	missense	probably damaging	1.00
R6479:Hmcn1	UTSW	1	150,553,053 (GRCm39)	nonsense	probably null
R6490:Hmcn1	UTSW	1	150,459,029 (GRCm39)	missense	probably benign	0.00
R6525:Hmcn1	UTSW	1	150,573,317 (GRCm39)	missense	probably damaging	1.00
R6571:Hmcn1	UTSW	1	150,491,189 (GRCm39)	splice site	probably null
R6612:Hmcn1	UTSW	1	150,470,869 (GRCm39)	critical splice donor site	probably null
R6616:Hmcn1	UTSW	1	150,599,008 (GRCm39)	critical splice donor site	probably null
R6617:Hmcn1	UTSW	1	150,619,547 (GRCm39)	missense	probably benign	0.01
R6623:Hmcn1	UTSW	1	150,634,057 (GRCm39)	missense	probably benign
R6687:Hmcn1	UTSW	1	150,620,784 (GRCm39)	missense	probably benign	0.30
R6714:Hmcn1	UTSW	1	150,579,926 (GRCm39)	missense	probably damaging	0.97
R6751:Hmcn1	UTSW	1	150,610,269 (GRCm39)	missense	probably damaging	0.98
R6831:Hmcn1	UTSW	1	150,646,044 (GRCm39)	missense	probably benign	0.00
R6971:Hmcn1	UTSW	1	150,868,802 (GRCm39)	start codon destroyed	probably benign	0.00
R7048:Hmcn1	UTSW	1	150,475,404 (GRCm39)	critical splice acceptor site	probably null
R7058:Hmcn1	UTSW	1	150,649,641 (GRCm39)	missense	probably benign	0.43
R7071:Hmcn1	UTSW	1	150,479,853 (GRCm39)	missense	probably damaging	1.00
R7078:Hmcn1	UTSW	1	150,736,118 (GRCm39)	missense	probably damaging	1.00
R7092:Hmcn1	UTSW	1	150,479,997 (GRCm39)	missense	probably damaging	1.00
R7120:Hmcn1	UTSW	1	150,576,292 (GRCm39)	missense	probably damaging	0.98
R7129:Hmcn1	UTSW	1	150,452,961 (GRCm39)	splice site	probably null
R7144:Hmcn1	UTSW	1	150,539,624 (GRCm39)	missense	probably damaging	1.00
R7148:Hmcn1	UTSW	1	150,562,605 (GRCm39)	missense	probably benign	0.00
R7162:Hmcn1	UTSW	1	150,624,744 (GRCm39)	missense	probably benign	0.18
R7172:Hmcn1	UTSW	1	150,629,450 (GRCm39)	missense	possibly damaging	0.92
R7193:Hmcn1	UTSW	1	150,525,331 (GRCm39)	missense	probably null	1.00
R7231:Hmcn1	UTSW	1	150,514,627 (GRCm39)	missense	probably benign	0.00
R7237:Hmcn1	UTSW	1	150,598,394 (GRCm39)	missense	probably damaging	0.98
R7258:Hmcn1	UTSW	1	150,591,574 (GRCm39)	missense	probably benign	0.12
R7286:Hmcn1	UTSW	1	150,458,088 (GRCm39)	missense	probably damaging	0.98
R7289:Hmcn1	UTSW	1	150,559,466 (GRCm39)	missense	possibly damaging	0.52
R7292:Hmcn1	UTSW	1	150,608,880 (GRCm39)	splice site	probably null
R7316:Hmcn1	UTSW	1	150,608,697 (GRCm39)	missense	probably damaging	1.00
R7327:Hmcn1	UTSW	1	150,479,565 (GRCm39)	missense	probably benign	0.01
R7328:Hmcn1	UTSW	1	150,514,617 (GRCm39)	missense	possibly damaging	0.95
R7346:Hmcn1	UTSW	1	150,559,496 (GRCm39)	missense	probably damaging	1.00
R7351:Hmcn1	UTSW	1	150,543,640 (GRCm39)	missense	probably damaging	0.98
R7354:Hmcn1	UTSW	1	150,682,196 (GRCm39)	nonsense	probably null
R7360:Hmcn1	UTSW	1	150,494,597 (GRCm39)	missense	probably damaging	1.00
R7396:Hmcn1	UTSW	1	150,439,382 (GRCm39)	missense	possibly damaging	0.83
R7398:Hmcn1	UTSW	1	150,522,421 (GRCm39)	missense	probably benign	0.00
R7400:Hmcn1	UTSW	1	150,550,181 (GRCm39)	missense	probably damaging	1.00
R7404:Hmcn1	UTSW	1	150,596,510 (GRCm39)	missense	probably benign	0.00
R7424:Hmcn1	UTSW	1	150,506,017 (GRCm39)	nonsense	probably null
R7454:Hmcn1	UTSW	1	150,439,355 (GRCm39)	missense	probably damaging	1.00
R7476:Hmcn1	UTSW	1	150,456,018 (GRCm39)	missense	probably damaging	0.99
R7480:Hmcn1	UTSW	1	150,552,985 (GRCm39)	critical splice donor site	probably null
R7516:Hmcn1	UTSW	1	150,498,718 (GRCm39)	missense	probably benign	0.35
R7526:Hmcn1	UTSW	1	150,532,324 (GRCm39)	missense	probably damaging	1.00
R7531:Hmcn1	UTSW	1	150,562,531 (GRCm39)	missense	probably benign	0.06
R7555:Hmcn1	UTSW	1	150,480,625 (GRCm39)	missense	probably benign	0.40
R7564:Hmcn1	UTSW	1	150,531,586 (GRCm39)	missense	probably benign
R7588:Hmcn1	UTSW	1	150,532,885 (GRCm39)	missense	possibly damaging	0.90
R7719:Hmcn1	UTSW	1	150,441,080 (GRCm39)	missense	possibly damaging	0.95
R7720:Hmcn1	UTSW	1	150,522,460 (GRCm39)	missense	probably benign	0.00
R7722:Hmcn1	UTSW	1	150,543,631 (GRCm39)	missense	probably damaging	0.98
R7761:Hmcn1	UTSW	1	150,598,196 (GRCm39)	missense	possibly damaging	0.70
R7787:Hmcn1	UTSW	1	150,632,343 (GRCm39)	missense	probably damaging	1.00
R7803:Hmcn1	UTSW	1	150,646,030 (GRCm39)	missense	probably benign	0.32
R7862:Hmcn1	UTSW	1	150,682,172 (GRCm39)	missense	probably damaging	0.96
R7876:Hmcn1	UTSW	1	150,620,722 (GRCm39)	missense	probably benign	0.03
R7886:Hmcn1	UTSW	1	150,533,221 (GRCm39)	missense	possibly damaging	0.94
R7891:Hmcn1	UTSW	1	150,468,940 (GRCm39)	missense	probably damaging	1.00
R7892:Hmcn1	UTSW	1	150,540,643 (GRCm39)	missense	probably benign	0.00
R7927:Hmcn1	UTSW	1	150,485,526 (GRCm39)	missense	probably damaging	1.00
R7941:Hmcn1	UTSW	1	150,525,835 (GRCm39)	missense	possibly damaging	0.95
R7960:Hmcn1	UTSW	1	150,531,606 (GRCm39)	missense	probably damaging	1.00
R8001:Hmcn1	UTSW	1	150,540,629 (GRCm39)	nonsense	probably null
R8015:Hmcn1	UTSW	1	150,474,062 (GRCm39)	missense	possibly damaging	0.83
R8070:Hmcn1	UTSW	1	150,525,743 (GRCm39)	nonsense	probably null
R8072:Hmcn1	UTSW	1	150,532,256 (GRCm39)	missense	possibly damaging	0.62
R8113:Hmcn1	UTSW	1	150,624,841 (GRCm39)	missense	possibly damaging	0.50
R8143:Hmcn1	UTSW	1	150,734,957 (GRCm39)	missense	probably benign	0.03
R8145:Hmcn1	UTSW	1	150,629,411 (GRCm39)	missense	probably benign	0.33
R8155:Hmcn1	UTSW	1	150,480,705 (GRCm39)	missense	probably damaging	1.00
R8165:Hmcn1	UTSW	1	150,522,409 (GRCm39)	missense	probably benign	0.09
R8179:Hmcn1	UTSW	1	150,598,265 (GRCm39)	missense	probably benign	0.19
R8193:Hmcn1	UTSW	1	150,453,228 (GRCm39)	nonsense	probably null
R8234:Hmcn1	UTSW	1	150,469,761 (GRCm39)	missense	possibly damaging	0.83
R8249:Hmcn1	UTSW	1	150,695,117 (GRCm39)	missense	probably benign	0.24
R8267:Hmcn1	UTSW	1	150,735,005 (GRCm39)	missense	probably damaging	1.00
R8312:Hmcn1	UTSW	1	150,614,515 (GRCm39)	missense	probably damaging	0.99
R8338:Hmcn1	UTSW	1	150,614,485 (GRCm39)	missense	probably benign	0.35
R8354:Hmcn1	UTSW	1	150,634,142 (GRCm39)	missense	possibly damaging	0.79
R8440:Hmcn1	UTSW	1	150,570,671 (GRCm39)	missense	probably damaging	1.00
R8473:Hmcn1	UTSW	1	150,479,551 (GRCm39)	missense	possibly damaging	0.64
R8497:Hmcn1	UTSW	1	150,455,990 (GRCm39)	missense	probably benign	0.01
R8509:Hmcn1	UTSW	1	150,449,302 (GRCm39)	nonsense	probably null
R8559:Hmcn1	UTSW	1	150,551,789 (GRCm39)	missense	probably benign	0.25
R8701:Hmcn1	UTSW	1	150,631,008 (GRCm39)	missense	probably benign	0.00
R8755:Hmcn1	UTSW	1	150,509,371 (GRCm39)	missense	probably benign	0.19
R8765:Hmcn1	UTSW	1	150,556,413 (GRCm39)	missense	probably damaging	0.98
R8782:Hmcn1	UTSW	1	150,540,636 (GRCm39)	missense	probably benign	0.08
R8794:Hmcn1	UTSW	1	150,591,469 (GRCm39)	missense	probably benign	0.00
R8803:Hmcn1	UTSW	1	150,610,248 (GRCm39)	missense	probably damaging	1.00
R8808:Hmcn1	UTSW	1	150,531,570 (GRCm39)	missense	possibly damaging	0.64
R8853:Hmcn1	UTSW	1	150,547,726 (GRCm39)	missense	probably damaging	1.00
R8877:Hmcn1	UTSW	1	150,514,659 (GRCm39)	missense	probably benign	0.00
R8881:Hmcn1	UTSW	1	150,525,723 (GRCm39)	missense	probably damaging	1.00
R8916:Hmcn1	UTSW	1	150,649,530 (GRCm39)	missense	probably damaging	1.00
R9008:Hmcn1	UTSW	1	150,630,795 (GRCm39)	intron	probably benign
R9030:Hmcn1	UTSW	1	150,692,870 (GRCm39)	missense	probably benign	0.00
R9072:Hmcn1	UTSW	1	150,565,320 (GRCm39)	missense	probably benign	0.04
R9090:Hmcn1	UTSW	1	150,632,309 (GRCm39)	missense	probably damaging	1.00
R9096:Hmcn1	UTSW	1	150,532,869 (GRCm39)	missense	probably benign	0.04
R9102:Hmcn1	UTSW	1	150,573,331 (GRCm39)	missense	probably benign	0.01
R9146:Hmcn1	UTSW	1	150,474,141 (GRCm39)	missense	probably benign	0.02
R9157:Hmcn1	UTSW	1	150,522,343 (GRCm39)	missense	probably benign	0.06
R9169:Hmcn1	UTSW	1	150,506,092 (GRCm39)	missense	probably damaging	0.99
R9182:Hmcn1	UTSW	1	150,488,405 (GRCm39)	missense	probably damaging	1.00
R9182:Hmcn1	UTSW	1	150,500,337 (GRCm39)	nonsense	probably null
R9204:Hmcn1	UTSW	1	150,610,262 (GRCm39)	missense	probably benign	0.40
R9219:Hmcn1	UTSW	1	150,594,844 (GRCm39)	critical splice donor site	probably null
R9267:Hmcn1	UTSW	1	150,473,740 (GRCm39)	missense	probably benign	0.26
R9271:Hmcn1	UTSW	1	150,632,309 (GRCm39)	missense	probably damaging	1.00
R9274:Hmcn1	UTSW	1	150,506,046 (GRCm39)	missense	probably benign	0.01
R9313:Hmcn1	UTSW	1	150,522,343 (GRCm39)	missense	probably benign	0.06
R9414:Hmcn1	UTSW	1	150,545,187 (GRCm39)	missense	probably damaging	1.00
R9456:Hmcn1	UTSW	1	150,506,053 (GRCm39)	nonsense	probably null
R9464:Hmcn1	UTSW	1	150,599,248 (GRCm39)	missense	possibly damaging	0.80
R9474:Hmcn1	UTSW	1	150,506,471 (GRCm39)	missense	probably damaging	1.00
R9476:Hmcn1	UTSW	1	150,462,127 (GRCm39)	missense	probably benign	0.00
R9482:Hmcn1	UTSW	1	150,610,281 (GRCm39)	missense	probably benign	0.06
R9501:Hmcn1	UTSW	1	150,470,990 (GRCm39)	missense	possibly damaging	0.67
R9510:Hmcn1	UTSW	1	150,462,127 (GRCm39)	missense	probably benign	0.00
R9529:Hmcn1	UTSW	1	150,545,175 (GRCm39)	missense	probably damaging	1.00
R9566:Hmcn1	UTSW	1	150,498,660 (GRCm39)	missense	probably benign	0.00
R9608:Hmcn1	UTSW	1	150,475,303 (GRCm39)	missense	probably damaging	1.00
R9609:Hmcn1	UTSW	1	150,555,346 (GRCm39)	missense	probably damaging	0.96
R9616:Hmcn1	UTSW	1	150,684,473 (GRCm39)	missense	probably benign	0.16
R9627:Hmcn1	UTSW	1	150,506,054 (GRCm39)	missense	probably damaging	1.00
R9668:Hmcn1	UTSW	1	150,619,492 (GRCm39)	missense	probably benign	0.02
R9686:Hmcn1	UTSW	1	150,613,356 (GRCm39)	missense	probably damaging	0.99
R9717:Hmcn1	UTSW	1	150,485,378 (GRCm39)	missense	probably damaging	1.00
R9727:Hmcn1	UTSW	1	150,674,566 (GRCm39)	missense	probably benign	0.06
R9744:Hmcn1	UTSW	1	150,623,941 (GRCm39)	missense	probably damaging	1.00
R9749:Hmcn1	UTSW	1	150,632,339 (GRCm39)	missense	possibly damaging	0.94
R9761:Hmcn1	UTSW	1	150,868,625 (GRCm39)	missense	probably damaging	0.98
R9783:Hmcn1	UTSW	1	150,598,380 (GRCm39)	missense	probably benign	0.16
R9788:Hmcn1	UTSW	1	150,528,333 (GRCm39)	missense	probably benign	0.00
R9792:Hmcn1	UTSW	1	150,608,689 (GRCm39)	missense	possibly damaging	0.94
R9793:Hmcn1	UTSW	1	150,608,689 (GRCm39)	missense	possibly damaging	0.94
R9795:Hmcn1	UTSW	1	150,608,689 (GRCm39)	missense	possibly damaging	0.94
R9802:Hmcn1	UTSW	1	150,684,391 (GRCm39)	missense	probably benign	0.07
RF003:Hmcn1	UTSW	1	150,500,312 (GRCm39)	missense	probably damaging	1.00
RF005:Hmcn1	UTSW	1	150,510,897 (GRCm39)	nonsense	probably null
X0022:Hmcn1	UTSW	1	150,576,281 (GRCm39)	missense	probably benign	0.04
X0027:Hmcn1	UTSW	1	150,736,127 (GRCm39)	missense	probably damaging	1.00
X0028:Hmcn1	UTSW	1	150,539,652 (GRCm39)	missense	probably damaging	1.00
Z1088:Hmcn1	UTSW	1	150,524,688 (GRCm39)	missense	probably damaging	1.00
Z1176:Hmcn1	UTSW	1	150,539,668 (GRCm39)	missense	probably benign	0.12
Z1176:Hmcn1	UTSW	1	150,531,672 (GRCm39)	missense	possibly damaging	0.65
Z1176:Hmcn1	UTSW	1	150,462,196 (GRCm39)	missense	probably null	0.92

Predicted Primers

PCR Primer
(F):5'- GGTTCATCCAACACCACTAATATTCTC -3'
(R):5'- TCTCAGGCAAGTAGGTGACC -3'

Sequencing Primer
(F):5'- CTATCACTTGAAATGTACCCTATCAG -3'
(R):5'- ACTCTACCTATGGCAGCA -3'

Posted On

2022-07-18