Mutagenetix > Incidental Mutation

Incidental Mutation 'R9564:Ylpm1'

721391

Institutional Source

Beutler Lab

Gene Symbol

Ylpm1

Ensembl Gene

ENSMUSG00000021244

Gene Name

YLP motif containing 1

Synonyms

A930013E17Rik, Zap3, ZAP

MMRRC Submission

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

R9564 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

85043095-85117289 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

C to T at 85091176 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Proline to Serine at position 1787 (P1787S)

Ref Sequence

ENSEMBL: ENSMUSP00000021670 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000021670] [ENSMUST00000101202] [ENSMUST00000164558] [ENSMUST00000168977]

AlphaFold

Q9R0I7

Predicted Effect

probably benign
Transcript: ENSMUST00000021670
AA Change: P1787S

PolyPhen 2 Score 0.301 (Sensitivity: 0.90; Specificity: 0.89)

SMART Domains

Protein: ENSMUSP00000021670
Gene: ENSMUSG00000021244
AA Change: P1787S

Domain	Start	End	E-Value	Type
low complexity region	15	26	N/A	INTRINSIC
low complexity region	31	50	N/A	INTRINSIC
low complexity region	57	78	N/A	INTRINSIC
low complexity region	79	91	N/A	INTRINSIC
low complexity region	94	114	N/A	INTRINSIC
low complexity region	139	225	N/A	INTRINSIC
low complexity region	226	253	N/A	INTRINSIC
low complexity region	341	382	N/A	INTRINSIC
low complexity region	389	407	N/A	INTRINSIC
low complexity region	422	435	N/A	INTRINSIC
low complexity region	455	464	N/A	INTRINSIC
low complexity region	538	654	N/A	INTRINSIC
low complexity region	688	696	N/A	INTRINSIC
low complexity region	751	763	N/A	INTRINSIC
internal_repeat_1	771	840	4.03e-5	PROSPERO
low complexity region	841	854	N/A	INTRINSIC
low complexity region	966	972	N/A	INTRINSIC
internal_repeat_1	1062	1124	4.03e-5	PROSPERO
low complexity region	1252	1266	N/A	INTRINSIC
low complexity region	1275	1293	N/A	INTRINSIC
low complexity region	1326	1338	N/A	INTRINSIC
low complexity region	1339	1353	N/A	INTRINSIC
low complexity region	1408	1425	N/A	INTRINSIC
coiled coil region	1447	1474	N/A	INTRINSIC
low complexity region	1494	1517	N/A	INTRINSIC
low complexity region	1518	1532	N/A	INTRINSIC
low complexity region	1536	1557	N/A	INTRINSIC
low complexity region	1598	1630	N/A	INTRINSIC
low complexity region	1678	1694	N/A	INTRINSIC
low complexity region	1705	1717	N/A	INTRINSIC
low complexity region	1720	1736	N/A	INTRINSIC
low complexity region	1797	1808	N/A	INTRINSIC
Pfam:AAA_33	1829	1990	7.8e-11	PFAM
coiled coil region	1995	2032	N/A	INTRINSIC

Predicted Effect

possibly damaging
Transcript: ENSMUST00000101202
AA Change: P1034S

PolyPhen 2 Score 0.466 (Sensitivity: 0.89; Specificity: 0.90)

SMART Domains

Protein: ENSMUSP00000098763
Gene: ENSMUSG00000021244
AA Change: P1034S

Domain	Start	End	E-Value	Type
low complexity region	15	26	N/A	INTRINSIC
low complexity region	31	50	N/A	INTRINSIC
low complexity region	57	78	N/A	INTRINSIC
low complexity region	79	91	N/A	INTRINSIC
low complexity region	94	114	N/A	INTRINSIC
low complexity region	139	206	N/A	INTRINSIC
low complexity region	294	335	N/A	INTRINSIC
low complexity region	342	360	N/A	INTRINSIC
low complexity region	375	388	N/A	INTRINSIC
low complexity region	408	417	N/A	INTRINSIC
low complexity region	491	607	N/A	INTRINSIC
low complexity region	641	649	N/A	INTRINSIC
low complexity region	741	764	N/A	INTRINSIC
low complexity region	765	779	N/A	INTRINSIC
low complexity region	783	804	N/A	INTRINSIC
low complexity region	845	877	N/A	INTRINSIC
low complexity region	925	941	N/A	INTRINSIC
low complexity region	952	964	N/A	INTRINSIC
low complexity region	967	983	N/A	INTRINSIC
low complexity region	1044	1055	N/A	INTRINSIC
Pfam:AAA_33	1076	1265	4.9e-11	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000164558
AA Change: P1329S

PolyPhen 2 Score 0.028 (Sensitivity: 0.95; Specificity: 0.81)

SMART Domains

Protein: ENSMUSP00000126347
Gene: ENSMUSG00000021244
AA Change: P1329S

Domain	Start	End	E-Value	Type
low complexity region	80	196	N/A	INTRINSIC
low complexity region	230	238	N/A	INTRINSIC
low complexity region	293	305	N/A	INTRINSIC
low complexity region	383	396	N/A	INTRINSIC
low complexity region	508	514	N/A	INTRINSIC
low complexity region	794	808	N/A	INTRINSIC
low complexity region	817	835	N/A	INTRINSIC
low complexity region	868	880	N/A	INTRINSIC
low complexity region	881	895	N/A	INTRINSIC
low complexity region	950	967	N/A	INTRINSIC
coiled coil region	989	1016	N/A	INTRINSIC
low complexity region	1036	1059	N/A	INTRINSIC
low complexity region	1060	1074	N/A	INTRINSIC
low complexity region	1078	1099	N/A	INTRINSIC
low complexity region	1140	1172	N/A	INTRINSIC
low complexity region	1220	1236	N/A	INTRINSIC
low complexity region	1247	1259	N/A	INTRINSIC
low complexity region	1262	1278	N/A	INTRINSIC
low complexity region	1339	1350	N/A	INTRINSIC
Pfam:AAA_33	1371	1559	5.2e-11	PFAM

Predicted Effect

possibly damaging
Transcript: ENSMUST00000168977
AA Change: P1081S

PolyPhen 2 Score 0.466 (Sensitivity: 0.89; Specificity: 0.90)

SMART Domains

Protein: ENSMUSP00000128962
Gene: ENSMUSG00000021244
AA Change: P1081S

Domain	Start	End	E-Value	Type
low complexity region	15	26	N/A	INTRINSIC
low complexity region	31	50	N/A	INTRINSIC
low complexity region	57	78	N/A	INTRINSIC
low complexity region	79	91	N/A	INTRINSIC
low complexity region	94	114	N/A	INTRINSIC
low complexity region	139	225	N/A	INTRINSIC
low complexity region	226	253	N/A	INTRINSIC
low complexity region	341	382	N/A	INTRINSIC
low complexity region	389	407	N/A	INTRINSIC
low complexity region	422	435	N/A	INTRINSIC
low complexity region	455	464	N/A	INTRINSIC
low complexity region	538	654	N/A	INTRINSIC
low complexity region	688	696	N/A	INTRINSIC
low complexity region	788	811	N/A	INTRINSIC
low complexity region	812	826	N/A	INTRINSIC
low complexity region	830	851	N/A	INTRINSIC
low complexity region	892	924	N/A	INTRINSIC
low complexity region	972	988	N/A	INTRINSIC
low complexity region	999	1011	N/A	INTRINSIC
low complexity region	1014	1030	N/A	INTRINSIC
low complexity region	1091	1102	N/A	INTRINSIC
Pfam:AAA_33	1123	1311	4.5e-11	PFAM

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.6%
20x: 98.8%

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 135 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
2700097O09Rik	A	T	12: 55,104,090 (GRCm39)	N176K	possibly damaging	Het
3110009E18Rik	T	A	1: 120,097,006 (GRCm39)	V134E		Het
Abca8a	T	A	11: 109,965,010 (GRCm39)	H429L	probably benign	Het
Acsf2	T	A	11: 94,463,891 (GRCm39)	I98F	possibly damaging	Het
Actr5	A	G	2: 158,470,135 (GRCm39)	D255G	probably damaging	Het
Adam21	C	T	12: 81,605,833 (GRCm39)	C643Y	probably damaging	Het
Adcy7	TGG	TG	8: 89,053,053 (GRCm39)		probably null	Het
AI429214	A	G	8: 37,461,067 (GRCm39)	S72G	possibly damaging	Het
Akap13	T	C	7: 75,259,161 (GRCm39)	V595A	probably benign	Het
Akt3	T	C	1: 176,907,769 (GRCm39)	T209A	possibly damaging	Het
Alpk2	C	T	18: 65,439,014 (GRCm39)	G793D	probably damaging	Het
Amotl1	T	C	9: 14,473,513 (GRCm39)	K562R	possibly damaging	Het
Ankib1	T	A	5: 3,805,733 (GRCm39)	N178I	possibly damaging	Het
Arfgef1	A	T	1: 10,217,758 (GRCm39)	D1560E	probably benign	Het
Arhgap20	AAGAGAG	AAGAG	9: 51,761,413 (GRCm39)		probably null	Het
Arpc5l	A	G	2: 38,905,124 (GRCm39)	T152A	probably benign	Het
Asic3	C	G	5: 24,620,875 (GRCm39)	D252E	possibly damaging	Het
Atf7	T	A	15: 102,442,712 (GRCm39)	M466L	probably benign	Het
Bcl9l	A	G	9: 44,420,554 (GRCm39)	D1320G	probably damaging	Het
Bdkrb1	G	A	12: 105,571,078 (GRCm39)	V215I	probably benign	Het
Brpf3	T	G	17: 29,026,152 (GRCm39)	D408E	probably benign	Het
Btn2a2	C	A	13: 23,662,848 (GRCm39)	K367N	possibly damaging	Het
Btnl10	T	A	11: 58,813,189 (GRCm39)	F273I	probably benign	Het
C1qtnf12	C	T	4: 156,049,473 (GRCm39)	T145I	probably benign	Het
Cacna1s	T	C	1: 136,046,516 (GRCm39)	C1763R	probably benign	Het
Ccdc154	C	A	17: 25,387,381 (GRCm39)	Q372K	possibly damaging	Het
Cd300ld2	CGAACTGTGGATGGCAGAACTGTGGATGTCAGAACTGTGGATGGCAGAACTGTGGATGTCAGAACTGTGGATGGCAGAACTGTGGATGTCAGAACTGTGGATGTCAGAACTGTGGATGGCACAACTGTGCATGGCAGAACTGTGGATGGCACAACTGTGGATGGCAGAACTGTGG	CGAACTGTGGATGGCAGAACTGTGGATGTCAGAACTGTGGATGGCAGAACTGTGGATGTCAGAACTGTGGATGTCAGAACTGTGGATGGCACAACTGTGCATGGCAGAACTGTGGATGGCACAACTGTGGATGGCAGAACTGTGG	11: 114,903,257 (GRCm39)		probably benign	Het
Celsr2	T	C	3: 108,321,834 (GRCm39)	Y326C	probably damaging	Het
Cfap46	A	T	7: 139,231,471 (GRCm39)	V914E		Het
Coil	T	A	11: 88,872,626 (GRCm39)	V329E	possibly damaging	Het
Copb1	A	G	7: 113,836,034 (GRCm39)	I449T	possibly damaging	Het
Copg1	T	G	6: 87,869,683 (GRCm39)	S187R	probably damaging	Het
Cps1	T	A	1: 67,198,048 (GRCm39)	F371Y	probably benign	Het
Cpt1b	A	T	15: 89,303,472 (GRCm39)	F554L	probably damaging	Het
Ctdsp2	A	G	10: 126,832,040 (GRCm39)	D216G	probably damaging	Het
Ctla2b	A	T	13: 61,043,856 (GRCm39)	Y104*	probably null	Het
Cyp2j6	A	G	4: 96,414,245 (GRCm39)	I340T	probably damaging	Het
Ddi1	T	A	9: 6,265,730 (GRCm39)	D213V	probably damaging	Het
Degs1l	G	T	1: 180,882,810 (GRCm39)	V191F	possibly damaging	Het
Dennd2b	G	T	7: 109,125,536 (GRCm39)	D980E	probably damaging	Het
Dlgap1	T	G	17: 70,964,458 (GRCm39)	N400K	probably benign	Het
Dnah5	G	A	15: 28,290,422 (GRCm39)	V1271M	probably benign	Het
Dnah8	T	A	17: 30,932,021 (GRCm39)	V1463E	probably benign	Het
Dstyk	G	A	1: 132,362,023 (GRCm39)	R151H	probably damaging	Het
Ehd3	T	G	17: 74,137,361 (GRCm39)	V510G	probably benign	Het
Enthd1	G	T	15: 80,444,235 (GRCm39)	Q107K	probably damaging	Het
Entpd7	A	G	19: 43,705,889 (GRCm39)	E237G	probably benign	Het
Fadd	A	T	7: 144,136,048 (GRCm39)	C27S	probably damaging	Het
Fan1	A	G	7: 63,999,240 (GRCm39)	L874P	possibly damaging	Het
Fbxw17	T	C	13: 50,579,605 (GRCm39)	W141R	probably damaging	Het
Fig4	A	G	10: 41,161,387 (GRCm39)	V63A	probably benign	Het
Fmo3	T	C	1: 162,786,021 (GRCm39)	D323G	probably damaging	Het
Gas8	T	A	8: 124,263,179 (GRCm39)	V452E	possibly damaging	Het
Gdf9	T	A	11: 53,327,511 (GRCm39)	S156T	probably damaging	Het
Hlcs	T	C	16: 93,935,580 (GRCm39)	S571G	probably benign	Het
Hmox2	A	G	16: 4,582,870 (GRCm39)	Y201C	probably damaging	Het
Ikzf3	T	A	11: 98,358,032 (GRCm39)	D435V	probably damaging	Het
Kank2	T	C	9: 21,705,852 (GRCm39)	T389A	possibly damaging	Het
Kank2	A	G	9: 21,706,631 (GRCm39)	L129P	probably damaging	Het
Kdr	T	A	5: 76,125,565 (GRCm39)	K339N	probably benign	Het
Lmntd2	A	G	7: 140,790,701 (GRCm39)	S516P		Het
Lrrc37	T	C	11: 103,503,822 (GRCm39)	I2715M	unknown	Het
Lrrc40	T	A	3: 157,746,078 (GRCm39)	V51D	probably benign	Het
Lrrtm1	A	G	6: 77,221,536 (GRCm39)	N331S	probably benign	Het
Lvrn	T	G	18: 47,017,506 (GRCm39)	I612S	probably damaging	Het
Map3k3	T	A	11: 106,041,860 (GRCm39)	I413N	probably damaging	Het
Mcm9	C	T	10: 53,506,104 (GRCm39)	A57T	possibly damaging	Het
Met	T	A	6: 17,531,425 (GRCm39)	F568I	probably benign	Het
Mkx	A	G	18: 7,002,457 (GRCm39)	F30L	probably benign	Het
Mrc1	A	G	2: 14,266,117 (GRCm39)	N345S	probably benign	Het
Mstn	T	A	1: 53,103,367 (GRCm39)	N234K	probably benign	Het
Mtmr3	A	T	11: 4,440,992 (GRCm39)	S554T	possibly damaging	Het
Mug1	G	A	6: 121,861,587 (GRCm39)	V1350I	probably benign	Het
Myh8	T	C	11: 67,177,215 (GRCm39)	V427A	probably benign	Het
Nr4a2	A	T	2: 57,000,190 (GRCm39)	I365N	probably damaging	Het
Nrxn2	A	G	19: 6,559,887 (GRCm39)	D1215G	probably damaging	Het
Or2d3c	A	G	7: 106,525,847 (GRCm39)	M273T	probably benign	Het
Or6c33	T	C	10: 129,853,287 (GRCm39)	I19T	probably benign	Het
Or7g18	G	A	9: 18,786,640 (GRCm39)	V3I	probably benign	Het
Osbpl6	T	A	2: 76,426,321 (GRCm39)	W967R	probably damaging	Het
Pcdhb21	T	C	18: 37,646,972 (GRCm39)	S34P	possibly damaging	Het
Pibf1	G	T	14: 99,374,610 (GRCm39)	D350Y	possibly damaging	Het
Pira1	C	T	7: 3,742,646 (GRCm39)	V21M	possibly damaging	Het
Plekhs1	A	T	19: 56,461,628 (GRCm39)	I123F	probably damaging	Het
Pold2	C	T	11: 5,824,163 (GRCm39)	G214D	probably benign	Het
Pomc	A	G	12: 4,009,971 (GRCm39)	T71A	probably benign	Het
Pot1b	A	G	17: 55,969,465 (GRCm39)	S568P	possibly damaging	Het
Prkd2	C	A	7: 16,591,744 (GRCm39)	Q592K	possibly damaging	Het
Prss28	C	T	17: 25,528,911 (GRCm39)	A84V	probably damaging	Het
Prtg	T	A	9: 72,766,153 (GRCm39)	Y649N	probably damaging	Het
Psip1	T	C	4: 83,386,888 (GRCm39)	E161G	possibly damaging	Het
Rab3gap2	A	G	1: 185,014,691 (GRCm39)	D1280G	probably damaging	Het
Rab3ip	A	T	10: 116,751,780 (GRCm39)	I329N	probably damaging	Het
Rarres2	C	T	6: 48,549,164 (GRCm39)	G13D	possibly damaging	Het
Rbp3	A	G	14: 33,677,477 (GRCm39)	D475G	probably damaging	Het
Ric3	A	G	7: 108,638,018 (GRCm39)	V246A	probably damaging	Het
Robo3	A	G	9: 37,340,900 (GRCm39)	F124S	probably damaging	Het
Rpl27a	C	A	7: 109,118,837 (GRCm39)	H17N	probably benign	Het
Rptn	A	G	3: 93,304,536 (GRCm39)	D623G	probably benign	Het
Rtl1	G	T	12: 109,556,713 (GRCm39)	Q1709K	probably benign	Het
Sacs	T	A	14: 61,449,046 (GRCm39)	D3697E	probably damaging	Het
Sec61b	A	G	4: 47,483,049 (GRCm39)	Y93C	probably damaging	Het
Serpina3a	A	T	12: 104,084,886 (GRCm39)	I94L	probably benign	Het
Skic2	C	T	17: 35,063,758 (GRCm39)	A562T	probably benign	Het
Skor2	C	T	18: 76,946,376 (GRCm39)	H33Y	unknown	Het
Slc12a3	G	A	8: 95,082,983 (GRCm39)	V874I	probably benign	Het
Slit1	T	A	19: 41,591,861 (GRCm39)	M1254L	probably benign	Het
Smg1	A	G	7: 117,812,208 (GRCm39)	S52P	unknown	Het
Sorl1	A	G	9: 41,957,893 (GRCm39)	Y584H	probably damaging	Het
Spata32	T	A	11: 103,099,779 (GRCm39)	Q242L	possibly damaging	Het
Sptbn4	T	G	7: 27,117,504 (GRCm39)	E415A	probably damaging	Het
St6galnac5	T	C	3: 152,545,782 (GRCm39)	R259G	probably damaging	Het
Stat3	T	C	11: 100,784,614 (GRCm39)	I589V	probably benign	Het
Tecta	T	A	9: 42,249,123 (GRCm39)	K1913M	probably damaging	Het
Tek	C	A	4: 94,762,172 (GRCm39)	N1103K	probably damaging	Het
Telo2	A	G	17: 25,334,199 (GRCm39)	I16T	probably benign	Het
Tmem207	G	T	16: 26,335,499 (GRCm39)	C79*	probably null	Het
Topaz1	C	T	9: 122,579,219 (GRCm39)	H710Y	probably benign	Het
Trim33	T	A	3: 103,238,965 (GRCm39)	S648T	probably benign	Het
Trpm6	A	G	19: 18,851,240 (GRCm39)	T1734A	possibly damaging	Het
Trpm8	A	G	1: 88,254,158 (GRCm39)	E127G	possibly damaging	Het
Ttc3	T	A	16: 94,248,918 (GRCm39)	C1139S	probably benign	Het
Ttn	T	C	2: 76,580,330 (GRCm39)	E23521G	probably damaging	Het
Ush2a	T	C	1: 188,268,551 (GRCm39)	I1669T	possibly damaging	Het
Vcpip1	C	A	1: 9,817,456 (GRCm39)	S309I	possibly damaging	Het
Vmn1r208	A	G	13: 22,956,789 (GRCm39)	V236A	probably damaging	Het
Vmn1r74	T	C	7: 11,581,534 (GRCm39)	F278S	probably damaging	Het
Vmn2r33	T	C	7: 7,557,081 (GRCm39)	S540G	probably benign	Het
Vmn2r52	T	C	7: 9,905,182 (GRCm39)	D219G	probably benign	Het
Wiz	G	T	17: 32,575,939 (GRCm39)	D812E	probably benign	Het
Zan	T	C	5: 137,404,688 (GRCm39)	E3858G	unknown	Het
Zfp760	T	G	17: 21,942,272 (GRCm39)	H482Q	possibly damaging	Het
Zfp78	A	G	7: 6,381,390 (GRCm39)	T147A	probably benign	Het
Zfp808	T	A	13: 62,320,661 (GRCm39)	I630K	possibly damaging	Het
Zpld1	T	A	16: 55,061,701 (GRCm39)	R227*	probably null	Het

Other mutations in Ylpm1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00539:Ylpm1	APN	12	85,075,728 (GRCm39)	missense	possibly damaging	0.93
IGL00809:Ylpm1	APN	12	85,095,968 (GRCm39)	missense	probably damaging	0.99
IGL01508:Ylpm1	APN	12	85,062,229 (GRCm39)	missense	possibly damaging	0.74
IGL02199:Ylpm1	APN	12	85,080,779 (GRCm39)	nonsense	probably null
IGL02392:Ylpm1	APN	12	85,061,731 (GRCm39)	missense	unknown
IGL02455:Ylpm1	APN	12	85,077,037 (GRCm39)	missense	probably damaging	1.00
IGL02506:Ylpm1	APN	12	85,095,965 (GRCm39)	missense	probably damaging	1.00
IGL03102:Ylpm1	APN	12	85,096,032 (GRCm39)	splice site	probably benign
I1329:Ylpm1	UTSW	12	85,087,654 (GRCm39)	missense	probably damaging	1.00
IGL02799:Ylpm1	UTSW	12	85,091,258 (GRCm39)	missense	probably damaging	1.00
R0010:Ylpm1	UTSW	12	85,075,800 (GRCm39)	missense	probably damaging	0.97
R0090:Ylpm1	UTSW	12	85,075,814 (GRCm39)	intron	probably benign
R0149:Ylpm1	UTSW	12	85,075,612 (GRCm39)	missense	probably damaging	0.99
R0226:Ylpm1	UTSW	12	85,096,511 (GRCm39)	missense	probably benign	0.21
R0375:Ylpm1	UTSW	12	85,061,754 (GRCm39)	missense	unknown
R0378:Ylpm1	UTSW	12	85,043,850 (GRCm39)	intron	probably benign
R0507:Ylpm1	UTSW	12	85,075,886 (GRCm39)	missense	probably benign	0.03
R0742:Ylpm1	UTSW	12	85,075,886 (GRCm39)	missense	probably benign	0.03
R1350:Ylpm1	UTSW	12	85,060,856 (GRCm39)	unclassified	probably benign
R1452:Ylpm1	UTSW	12	85,077,157 (GRCm39)	missense	possibly damaging	0.94
R1500:Ylpm1	UTSW	12	85,061,770 (GRCm39)	missense	unknown
R1837:Ylpm1	UTSW	12	85,076,107 (GRCm39)	missense	possibly damaging	0.92
R1945:Ylpm1	UTSW	12	85,062,192 (GRCm39)	missense	probably damaging	0.98
R1971:Ylpm1	UTSW	12	85,087,560 (GRCm39)	missense	probably damaging	1.00
R2211:Ylpm1	UTSW	12	85,091,152 (GRCm39)	nonsense	probably null
R2213:Ylpm1	UTSW	12	85,116,492 (GRCm39)	missense	probably benign	0.25
R2269:Ylpm1	UTSW	12	85,061,824 (GRCm39)	missense	unknown
R2300:Ylpm1	UTSW	12	85,107,093 (GRCm39)	splice site	probably null
R2439:Ylpm1	UTSW	12	85,060,891 (GRCm39)	unclassified	probably benign
R2497:Ylpm1	UTSW	12	85,043,535 (GRCm39)	missense	probably damaging	0.98
R2890:Ylpm1	UTSW	12	85,076,587 (GRCm39)	missense	probably damaging	0.99
R3111:Ylpm1	UTSW	12	85,076,145 (GRCm39)	missense	probably damaging	0.98
R3436:Ylpm1	UTSW	12	85,096,644 (GRCm39)	critical splice donor site	probably null
R3437:Ylpm1	UTSW	12	85,096,644 (GRCm39)	critical splice donor site	probably null
R4156:Ylpm1	UTSW	12	85,104,177 (GRCm39)	intron	probably benign
R4157:Ylpm1	UTSW	12	85,104,177 (GRCm39)	intron	probably benign
R4959:Ylpm1	UTSW	12	85,096,719 (GRCm39)	missense	probably damaging	1.00
R5014:Ylpm1	UTSW	12	85,061,523 (GRCm39)	missense	unknown
R5039:Ylpm1	UTSW	12	85,089,013 (GRCm39)	missense	probably damaging	1.00
R5039:Ylpm1	UTSW	12	85,062,267 (GRCm39)	missense	probably damaging	0.98
R5084:Ylpm1	UTSW	12	85,076,095 (GRCm39)	missense	probably damaging	0.99
R5325:Ylpm1	UTSW	12	85,060,735 (GRCm39)	unclassified	probably benign
R5378:Ylpm1	UTSW	12	85,077,029 (GRCm39)	missense	probably damaging	0.99
R5428:Ylpm1	UTSW	12	85,077,003 (GRCm39)	missense	probably benign	0.04
R5467:Ylpm1	UTSW	12	85,043,633 (GRCm39)	missense	unknown
R5605:Ylpm1	UTSW	12	85,075,627 (GRCm39)	missense	probably damaging	1.00
R5614:Ylpm1	UTSW	12	85,111,718 (GRCm39)	intron	probably benign
R5748:Ylpm1	UTSW	12	85,107,025 (GRCm39)	splice site	probably null
R5860:Ylpm1	UTSW	12	85,087,660 (GRCm39)	missense	probably damaging	1.00
R5861:Ylpm1	UTSW	12	85,087,660 (GRCm39)	missense	probably damaging	1.00
R5881:Ylpm1	UTSW	12	85,088,899 (GRCm39)	missense	probably damaging	1.00
R5909:Ylpm1	UTSW	12	85,087,660 (GRCm39)	missense	probably damaging	1.00
R5912:Ylpm1	UTSW	12	85,087,660 (GRCm39)	missense	probably damaging	1.00
R5915:Ylpm1	UTSW	12	85,087,660 (GRCm39)	missense	probably damaging	1.00
R6000:Ylpm1	UTSW	12	85,044,030 (GRCm39)	missense	unknown
R6004:Ylpm1	UTSW	12	85,075,858 (GRCm39)	missense	possibly damaging	0.78
R6007:Ylpm1	UTSW	12	85,076,064 (GRCm39)	missense	probably benign	0.33
R6053:Ylpm1	UTSW	12	85,043,277 (GRCm39)	missense	possibly damaging	0.72
R6104:Ylpm1	UTSW	12	85,076,404 (GRCm39)	missense	probably benign	0.00
R6197:Ylpm1	UTSW	12	85,088,953 (GRCm39)	missense	probably damaging	1.00
R6293:Ylpm1	UTSW	12	85,062,051 (GRCm39)	missense	unknown
R6297:Ylpm1	UTSW	12	85,062,051 (GRCm39)	missense	unknown
R6305:Ylpm1	UTSW	12	85,077,319 (GRCm39)	missense	probably damaging	1.00
R6379:Ylpm1	UTSW	12	85,077,574 (GRCm39)	missense	probably damaging	1.00
R6465:Ylpm1	UTSW	12	85,096,576 (GRCm39)	missense	probably damaging	1.00
R6608:Ylpm1	UTSW	12	85,062,051 (GRCm39)	missense	unknown
R6609:Ylpm1	UTSW	12	85,062,051 (GRCm39)	missense	unknown
R6737:Ylpm1	UTSW	12	85,077,620 (GRCm39)	missense	probably damaging	0.98
R6794:Ylpm1	UTSW	12	85,043,655 (GRCm39)	missense	unknown
R7383:Ylpm1	UTSW	12	85,091,242 (GRCm39)	missense	possibly damaging	0.93
R7514:Ylpm1	UTSW	12	85,077,268 (GRCm39)	missense	possibly damaging	0.94
R7577:Ylpm1	UTSW	12	85,043,994 (GRCm39)	missense	unknown
R7709:Ylpm1	UTSW	12	85,059,799 (GRCm39)	missense	unknown
R7718:Ylpm1	UTSW	12	85,075,896 (GRCm39)	missense	probably damaging	0.99
R7736:Ylpm1	UTSW	12	85,059,757 (GRCm39)	missense	unknown
R7758:Ylpm1	UTSW	12	85,061,796 (GRCm39)	missense	unknown
R7807:Ylpm1	UTSW	12	85,060,855 (GRCm39)	nonsense	probably null
R7838:Ylpm1	UTSW	12	85,095,640 (GRCm39)	missense	possibly damaging	0.90
R7846:Ylpm1	UTSW	12	85,104,042 (GRCm39)	missense	probably damaging	0.98
R8170:Ylpm1	UTSW	12	85,080,801 (GRCm39)	missense	probably benign	0.40
R8776:Ylpm1	UTSW	12	85,077,195 (GRCm39)	missense	probably damaging	1.00
R8776-TAIL:Ylpm1	UTSW	12	85,077,195 (GRCm39)	missense	probably damaging	1.00
R8812:Ylpm1	UTSW	12	85,043,566 (GRCm39)	missense	unknown
R8847:Ylpm1	UTSW	12	85,061,672 (GRCm39)	missense	unknown
R8874:Ylpm1	UTSW	12	85,116,394 (GRCm39)	missense	probably damaging	1.00
R9129:Ylpm1	UTSW	12	85,104,052 (GRCm39)	missense
R9165:Ylpm1	UTSW	12	85,077,342 (GRCm39)	missense	probably damaging	1.00
R9198:Ylpm1	UTSW	12	85,080,689 (GRCm39)	critical splice acceptor site	probably null
R9629:Ylpm1	UTSW	12	85,044,036 (GRCm39)	missense	unknown
R9797:Ylpm1	UTSW	12	85,077,109 (GRCm39)	missense	possibly damaging	0.86
Z1088:Ylpm1	UTSW	12	85,076,929 (GRCm39)	missense	possibly damaging	0.95
Z1176:Ylpm1	UTSW	12	85,077,058 (GRCm39)	missense	possibly damaging	0.93
Z1177:Ylpm1	UTSW	12	85,104,057 (GRCm39)	missense	probably damaging	0.98

Predicted Primers

PCR Primer
(F):5'- CAAATGGGCCAGTCTTTTCATTTTC -3'
(R):5'- GGAGCCAGTATTTCTATGTTGC -3'

Sequencing Primer
(F):5'- GCCAGTCTTTTCATTTTCTTGATTAC -3'
(R):5'- GCCAGTATTTCTATGTTGCAGAAAAC -3'

Posted On

2022-08-09