Incidental Mutation 'R0226:Ylpm1'
| ID |
33952 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ylpm1
|
| Ensembl Gene |
ENSMUSG00000021244 |
| Gene Name |
YLP motif containing 1 |
| Synonyms |
A930013E17Rik, Zap3, ZAP |
| MMRRC Submission |
038471-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R0226 (G1)
|
| Quality Score |
204 |
|
Status
|
Validated
|
| Chromosome |
12 |
| Chromosomal Location |
85043095-85117289 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 85096511 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Alanine
at position 1446
(T1446A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000126347
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000021670]
[ENSMUST00000101202]
[ENSMUST00000164558]
[ENSMUST00000168977]
|
| AlphaFold |
Q9R0I7 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000021670
AA Change: T1904A
PolyPhen 2
Score 0.132 (Sensitivity: 0.93; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000021670
Gene: ENSMUSG00000021244
AA Change: T1904A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
26 |
N/A |
INTRINSIC |
|
low complexity region
|
31 |
50 |
N/A |
INTRINSIC |
|
low complexity region
|
57 |
78 |
N/A |
INTRINSIC |
|
low complexity region
|
79 |
91 |
N/A |
INTRINSIC |
|
low complexity region
|
94 |
114 |
N/A |
INTRINSIC |
|
low complexity region
|
139 |
225 |
N/A |
INTRINSIC |
|
low complexity region
|
226 |
253 |
N/A |
INTRINSIC |
|
low complexity region
|
341 |
382 |
N/A |
INTRINSIC |
|
low complexity region
|
389 |
407 |
N/A |
INTRINSIC |
|
low complexity region
|
422 |
435 |
N/A |
INTRINSIC |
|
low complexity region
|
455 |
464 |
N/A |
INTRINSIC |
|
low complexity region
|
538 |
654 |
N/A |
INTRINSIC |
|
low complexity region
|
688 |
696 |
N/A |
INTRINSIC |
|
low complexity region
|
751 |
763 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
771 |
840 |
4.03e-5 |
PROSPERO |
|
low complexity region
|
841 |
854 |
N/A |
INTRINSIC |
|
low complexity region
|
966 |
972 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
1062 |
1124 |
4.03e-5 |
PROSPERO |
|
low complexity region
|
1252 |
1266 |
N/A |
INTRINSIC |
|
low complexity region
|
1275 |
1293 |
N/A |
INTRINSIC |
|
low complexity region
|
1326 |
1338 |
N/A |
INTRINSIC |
|
low complexity region
|
1339 |
1353 |
N/A |
INTRINSIC |
|
low complexity region
|
1408 |
1425 |
N/A |
INTRINSIC |
|
coiled coil region
|
1447 |
1474 |
N/A |
INTRINSIC |
|
low complexity region
|
1494 |
1517 |
N/A |
INTRINSIC |
|
low complexity region
|
1518 |
1532 |
N/A |
INTRINSIC |
|
low complexity region
|
1536 |
1557 |
N/A |
INTRINSIC |
|
low complexity region
|
1598 |
1630 |
N/A |
INTRINSIC |
|
low complexity region
|
1678 |
1694 |
N/A |
INTRINSIC |
|
low complexity region
|
1705 |
1717 |
N/A |
INTRINSIC |
|
low complexity region
|
1720 |
1736 |
N/A |
INTRINSIC |
|
low complexity region
|
1797 |
1808 |
N/A |
INTRINSIC |
|
Pfam:AAA_33
|
1829 |
1990 |
7.8e-11 |
PFAM |
|
coiled coil region
|
1995 |
2032 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000101202
AA Change: T1151A
PolyPhen 2
Score 0.070 (Sensitivity: 0.94; Specificity: 0.84)
|
| SMART Domains |
Protein: ENSMUSP00000098763
Gene: ENSMUSG00000021244
AA Change: T1151A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
26 |
N/A |
INTRINSIC |
|
low complexity region
|
31 |
50 |
N/A |
INTRINSIC |
|
low complexity region
|
57 |
78 |
N/A |
INTRINSIC |
|
low complexity region
|
79 |
91 |
N/A |
INTRINSIC |
|
low complexity region
|
94 |
114 |
N/A |
INTRINSIC |
|
low complexity region
|
139 |
206 |
N/A |
INTRINSIC |
|
low complexity region
|
294 |
335 |
N/A |
INTRINSIC |
|
low complexity region
|
342 |
360 |
N/A |
INTRINSIC |
|
low complexity region
|
375 |
388 |
N/A |
INTRINSIC |
|
low complexity region
|
408 |
417 |
N/A |
INTRINSIC |
|
low complexity region
|
491 |
607 |
N/A |
INTRINSIC |
|
low complexity region
|
641 |
649 |
N/A |
INTRINSIC |
|
low complexity region
|
741 |
764 |
N/A |
INTRINSIC |
|
low complexity region
|
765 |
779 |
N/A |
INTRINSIC |
|
low complexity region
|
783 |
804 |
N/A |
INTRINSIC |
|
low complexity region
|
845 |
877 |
N/A |
INTRINSIC |
|
low complexity region
|
925 |
941 |
N/A |
INTRINSIC |
|
low complexity region
|
952 |
964 |
N/A |
INTRINSIC |
|
low complexity region
|
967 |
983 |
N/A |
INTRINSIC |
|
low complexity region
|
1044 |
1055 |
N/A |
INTRINSIC |
|
Pfam:AAA_33
|
1076 |
1265 |
4.9e-11 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000164558
AA Change: T1446A
PolyPhen 2
Score 0.206 (Sensitivity: 0.92; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000126347
Gene: ENSMUSG00000021244
AA Change: T1446A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
80 |
196 |
N/A |
INTRINSIC |
|
low complexity region
|
230 |
238 |
N/A |
INTRINSIC |
|
low complexity region
|
293 |
305 |
N/A |
INTRINSIC |
|
low complexity region
|
383 |
396 |
N/A |
INTRINSIC |
|
low complexity region
|
508 |
514 |
N/A |
INTRINSIC |
|
low complexity region
|
794 |
808 |
N/A |
INTRINSIC |
|
low complexity region
|
817 |
835 |
N/A |
INTRINSIC |
|
low complexity region
|
868 |
880 |
N/A |
INTRINSIC |
|
low complexity region
|
881 |
895 |
N/A |
INTRINSIC |
|
low complexity region
|
950 |
967 |
N/A |
INTRINSIC |
|
coiled coil region
|
989 |
1016 |
N/A |
INTRINSIC |
|
low complexity region
|
1036 |
1059 |
N/A |
INTRINSIC |
|
low complexity region
|
1060 |
1074 |
N/A |
INTRINSIC |
|
low complexity region
|
1078 |
1099 |
N/A |
INTRINSIC |
|
low complexity region
|
1140 |
1172 |
N/A |
INTRINSIC |
|
low complexity region
|
1220 |
1236 |
N/A |
INTRINSIC |
|
low complexity region
|
1247 |
1259 |
N/A |
INTRINSIC |
|
low complexity region
|
1262 |
1278 |
N/A |
INTRINSIC |
|
low complexity region
|
1339 |
1350 |
N/A |
INTRINSIC |
|
Pfam:AAA_33
|
1371 |
1559 |
5.2e-11 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000165803
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000168977
AA Change: T1198A
PolyPhen 2
Score 0.070 (Sensitivity: 0.94; Specificity: 0.84)
|
| SMART Domains |
Protein: ENSMUSP00000128962
Gene: ENSMUSG00000021244
AA Change: T1198A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
26 |
N/A |
INTRINSIC |
|
low complexity region
|
31 |
50 |
N/A |
INTRINSIC |
|
low complexity region
|
57 |
78 |
N/A |
INTRINSIC |
|
low complexity region
|
79 |
91 |
N/A |
INTRINSIC |
|
low complexity region
|
94 |
114 |
N/A |
INTRINSIC |
|
low complexity region
|
139 |
225 |
N/A |
INTRINSIC |
|
low complexity region
|
226 |
253 |
N/A |
INTRINSIC |
|
low complexity region
|
341 |
382 |
N/A |
INTRINSIC |
|
low complexity region
|
389 |
407 |
N/A |
INTRINSIC |
|
low complexity region
|
422 |
435 |
N/A |
INTRINSIC |
|
low complexity region
|
455 |
464 |
N/A |
INTRINSIC |
|
low complexity region
|
538 |
654 |
N/A |
INTRINSIC |
|
low complexity region
|
688 |
696 |
N/A |
INTRINSIC |
|
low complexity region
|
788 |
811 |
N/A |
INTRINSIC |
|
low complexity region
|
812 |
826 |
N/A |
INTRINSIC |
|
low complexity region
|
830 |
851 |
N/A |
INTRINSIC |
|
low complexity region
|
892 |
924 |
N/A |
INTRINSIC |
|
low complexity region
|
972 |
988 |
N/A |
INTRINSIC |
|
low complexity region
|
999 |
1011 |
N/A |
INTRINSIC |
|
low complexity region
|
1014 |
1030 |
N/A |
INTRINSIC |
|
low complexity region
|
1091 |
1102 |
N/A |
INTRINSIC |
|
Pfam:AAA_33
|
1123 |
1311 |
4.5e-11 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000169150
|
| Meta Mutation Damage Score |
0.0829 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.8%
- 20x: 94.4%
|
| Validation Efficiency |
100% (98/98) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 90 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700129C05Rik |
G |
T |
14: 59,379,569 (GRCm39) |
T54K |
possibly damaging |
Het |
| 2210408I21Rik |
A |
T |
13: 77,451,544 (GRCm39) |
E876V |
possibly damaging |
Het |
| Aasdh |
A |
T |
5: 77,049,849 (GRCm39) |
L49Q |
probably damaging |
Het |
| Abca8b |
T |
C |
11: 109,847,844 (GRCm39) |
|
probably null |
Het |
| Ablim1 |
A |
T |
19: 57,032,302 (GRCm39) |
L556Q |
probably damaging |
Het |
| Afdn |
A |
G |
17: 14,119,408 (GRCm39) |
T1700A |
probably benign |
Het |
| Agl |
G |
A |
3: 116,545,720 (GRCm39) |
R1359C |
probably damaging |
Het |
| Agpat3 |
T |
A |
10: 78,113,863 (GRCm39) |
H275L |
possibly damaging |
Het |
| Ahcyl1 |
A |
T |
3: 107,577,586 (GRCm39) |
C180* |
probably null |
Het |
| Aim2 |
A |
G |
1: 173,289,899 (GRCm39) |
|
probably benign |
Het |
| Angpt1 |
T |
C |
15: 42,331,631 (GRCm39) |
N320S |
probably benign |
Het |
| Ankrd52 |
T |
A |
10: 128,225,727 (GRCm39) |
|
probably null |
Het |
| Ap1g1 |
C |
T |
8: 110,581,694 (GRCm39) |
S654L |
probably benign |
Het |
| Bpifa1 |
T |
A |
2: 153,987,977 (GRCm39) |
S173R |
probably benign |
Het |
| Brd8 |
T |
C |
18: 34,736,947 (GRCm39) |
|
probably benign |
Het |
| Btbd9 |
C |
T |
17: 30,493,916 (GRCm39) |
D492N |
possibly damaging |
Het |
| C1qtnf2 |
A |
G |
11: 43,381,670 (GRCm39) |
T161A |
probably benign |
Het |
| Car6 |
T |
C |
4: 150,271,965 (GRCm39) |
Y228C |
probably damaging |
Het |
| Ccdc149 |
A |
G |
5: 52,557,559 (GRCm39) |
L273P |
probably damaging |
Het |
| Cit |
G |
A |
5: 116,122,899 (GRCm39) |
R1405Q |
probably damaging |
Het |
| Cox17 |
T |
C |
16: 38,169,638 (GRCm39) |
L48P |
probably damaging |
Het |
| Cttn |
A |
G |
7: 143,995,589 (GRCm39) |
|
probably benign |
Het |
| Cyp4f18 |
T |
C |
8: 72,743,619 (GRCm39) |
|
probably benign |
Het |
| Dtnbp1 |
A |
G |
13: 45,076,669 (GRCm39) |
L175P |
probably damaging |
Het |
| Efl1 |
T |
C |
7: 82,342,219 (GRCm39) |
|
probably benign |
Het |
| Fbn1 |
C |
T |
2: 125,162,830 (GRCm39) |
R2152Q |
possibly damaging |
Het |
| Fignl1 |
A |
T |
11: 11,751,061 (GRCm39) |
S665T |
probably benign |
Het |
| Gm9843 |
A |
T |
16: 76,200,449 (GRCm39) |
|
noncoding transcript |
Het |
| Gpr155 |
C |
T |
2: 73,197,936 (GRCm39) |
V395I |
probably benign |
Het |
| Greb1l |
T |
C |
18: 10,522,076 (GRCm39) |
|
probably benign |
Het |
| Hdgfl1 |
A |
T |
13: 26,953,979 (GRCm39) |
H31Q |
probably benign |
Het |
| Heatr1 |
T |
C |
13: 12,425,443 (GRCm39) |
S628P |
probably damaging |
Het |
| Hivep2 |
A |
G |
10: 14,005,456 (GRCm39) |
T685A |
probably benign |
Het |
| Hmgcl |
T |
G |
4: 135,686,039 (GRCm39) |
V168G |
probably damaging |
Het |
| Itch |
T |
C |
2: 155,041,314 (GRCm39) |
I454T |
probably benign |
Het |
| Itih2 |
T |
C |
2: 10,120,110 (GRCm39) |
D309G |
possibly damaging |
Het |
| Kcmf1 |
T |
C |
6: 72,819,935 (GRCm39) |
I304V |
probably benign |
Het |
| Kcnh1 |
G |
A |
1: 191,959,112 (GRCm39) |
W222* |
probably null |
Het |
| Kcnh1 |
G |
T |
1: 191,959,113 (GRCm39) |
W222C |
probably damaging |
Het |
| Kif24 |
T |
A |
4: 41,414,939 (GRCm39) |
K287* |
probably null |
Het |
| Lrig3 |
A |
G |
10: 125,807,986 (GRCm39) |
|
probably benign |
Het |
| Lrp2 |
A |
T |
2: 69,367,907 (GRCm39) |
C202S |
probably null |
Het |
| Lrrc37 |
A |
T |
11: 103,494,067 (GRCm39) |
F663L |
probably benign |
Het |
| Lrrn2 |
A |
G |
1: 132,865,558 (GRCm39) |
N208D |
probably damaging |
Het |
| Mcm5 |
C |
T |
8: 75,852,880 (GRCm39) |
T664I |
possibly damaging |
Het |
| Mfsd10 |
A |
G |
5: 34,791,790 (GRCm39) |
L365S |
probably benign |
Het |
| Mfsd6 |
A |
G |
1: 52,697,849 (GRCm39) |
|
probably benign |
Het |
| Mgat4e |
A |
G |
1: 134,468,841 (GRCm39) |
V401A |
probably benign |
Het |
| Mllt3 |
C |
A |
4: 87,758,969 (GRCm39) |
V360L |
probably benign |
Het |
| Mrm1 |
G |
A |
11: 84,709,996 (GRCm39) |
A68V |
possibly damaging |
Het |
| Myo19 |
A |
G |
11: 84,788,558 (GRCm39) |
|
probably benign |
Het |
| Myo3b |
A |
G |
2: 70,047,510 (GRCm39) |
T311A |
probably benign |
Het |
| Myo5b |
T |
C |
18: 74,875,251 (GRCm39) |
F1552L |
probably benign |
Het |
| Myo7b |
C |
T |
18: 32,105,949 (GRCm39) |
V1353I |
probably benign |
Het |
| Myo9b |
T |
C |
8: 71,806,476 (GRCm39) |
S1512P |
probably damaging |
Het |
| Nanos3 |
C |
T |
8: 84,902,763 (GRCm39) |
R133Q |
probably damaging |
Het |
| Osbpl3 |
A |
G |
6: 50,329,988 (GRCm39) |
W63R |
probably damaging |
Het |
| Pcdh17 |
T |
C |
14: 84,685,641 (GRCm39) |
S703P |
probably damaging |
Het |
| Pclo |
T |
C |
5: 14,815,237 (GRCm39) |
I1231T |
probably damaging |
Het |
| Pex16 |
A |
C |
2: 92,206,032 (GRCm39) |
|
probably benign |
Het |
| Pfkl |
T |
C |
10: 77,828,368 (GRCm39) |
N399S |
probably benign |
Het |
| Pkhd1l1 |
G |
A |
15: 44,390,180 (GRCm39) |
R1432K |
possibly damaging |
Het |
| Prdm1 |
T |
A |
10: 44,332,692 (GRCm39) |
T106S |
probably benign |
Het |
| Prrc1 |
A |
G |
18: 57,496,363 (GRCm39) |
M105V |
probably benign |
Het |
| Psg26 |
A |
G |
7: 18,217,883 (GRCm39) |
C12R |
possibly damaging |
Het |
| Rnf43 |
A |
T |
11: 87,622,263 (GRCm39) |
S455C |
probably damaging |
Het |
| Ryr2 |
T |
C |
13: 11,787,442 (GRCm39) |
K977R |
probably damaging |
Het |
| Sart1 |
C |
T |
19: 5,431,150 (GRCm39) |
|
probably benign |
Het |
| Sec14l5 |
A |
G |
16: 4,998,167 (GRCm39) |
S509G |
probably benign |
Het |
| Sin3b |
A |
T |
8: 73,471,136 (GRCm39) |
E361V |
probably benign |
Het |
| Slc35e3 |
C |
T |
10: 117,576,795 (GRCm39) |
E179K |
possibly damaging |
Het |
| Sntb2 |
T |
C |
8: 107,728,215 (GRCm39) |
S388P |
probably damaging |
Het |
| Srms |
A |
G |
2: 180,854,175 (GRCm39) |
S131P |
probably benign |
Het |
| Sting1 |
A |
T |
18: 35,872,141 (GRCm39) |
F120L |
probably benign |
Het |
| Stxbp5 |
T |
C |
10: 9,742,442 (GRCm39) |
|
probably benign |
Het |
| Taar2 |
T |
C |
10: 23,816,961 (GRCm39) |
V167A |
probably damaging |
Het |
| Taar2 |
G |
A |
10: 23,817,393 (GRCm39) |
R311H |
probably benign |
Het |
| Thsd7a |
A |
G |
6: 12,321,899 (GRCm39) |
Y1516H |
possibly damaging |
Het |
| Tlk1 |
T |
A |
2: 70,544,513 (GRCm39) |
|
probably benign |
Het |
| Tnfaip3 |
T |
C |
10: 18,878,495 (GRCm39) |
K771R |
probably damaging |
Het |
| Treml1 |
C |
T |
17: 48,667,486 (GRCm39) |
L124F |
probably damaging |
Het |
| Ttn |
G |
T |
2: 76,611,141 (GRCm39) |
Q9137K |
possibly damaging |
Het |
| Unkl |
T |
A |
17: 25,449,685 (GRCm39) |
I469N |
probably damaging |
Het |
| Vmn1r173 |
G |
T |
7: 23,402,508 (GRCm39) |
V248L |
possibly damaging |
Het |
| Vps35 |
T |
C |
8: 86,000,204 (GRCm39) |
Q474R |
probably damaging |
Het |
| Wdr17 |
T |
A |
8: 55,116,043 (GRCm39) |
T580S |
probably benign |
Het |
| Xpnpep1 |
T |
C |
19: 52,998,583 (GRCm39) |
K222E |
probably benign |
Het |
| Zfp277 |
A |
G |
12: 40,414,161 (GRCm39) |
L228S |
possibly damaging |
Het |
| Zfp941 |
T |
A |
7: 140,393,188 (GRCm39) |
K57M |
probably damaging |
Het |
| Zmpste24 |
A |
T |
4: 120,938,406 (GRCm39) |
S244R |
probably benign |
Het |
|
| Other mutations in Ylpm1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00539:Ylpm1
|
APN |
12 |
85,075,728 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL00809:Ylpm1
|
APN |
12 |
85,095,968 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01508:Ylpm1
|
APN |
12 |
85,062,229 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
IGL02199:Ylpm1
|
APN |
12 |
85,080,779 (GRCm39) |
nonsense |
probably null |
|
|
IGL02392:Ylpm1
|
APN |
12 |
85,061,731 (GRCm39) |
missense |
unknown |
|
|
IGL02455:Ylpm1
|
APN |
12 |
85,077,037 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02506:Ylpm1
|
APN |
12 |
85,095,965 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03102:Ylpm1
|
APN |
12 |
85,096,032 (GRCm39) |
splice site |
probably benign |
|
|
I1329:Ylpm1
|
UTSW |
12 |
85,087,654 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02799:Ylpm1
|
UTSW |
12 |
85,091,258 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0010:Ylpm1
|
UTSW |
12 |
85,075,800 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0090:Ylpm1
|
UTSW |
12 |
85,075,814 (GRCm39) |
intron |
probably benign |
|
|
R0149:Ylpm1
|
UTSW |
12 |
85,075,612 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0375:Ylpm1
|
UTSW |
12 |
85,061,754 (GRCm39) |
missense |
unknown |
|
|
R0378:Ylpm1
|
UTSW |
12 |
85,043,850 (GRCm39) |
intron |
probably benign |
|
|
R0507:Ylpm1
|
UTSW |
12 |
85,075,886 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0742:Ylpm1
|
UTSW |
12 |
85,075,886 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1350:Ylpm1
|
UTSW |
12 |
85,060,856 (GRCm39) |
unclassified |
probably benign |
|
|
R1452:Ylpm1
|
UTSW |
12 |
85,077,157 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1500:Ylpm1
|
UTSW |
12 |
85,061,770 (GRCm39) |
missense |
unknown |
|
|
R1837:Ylpm1
|
UTSW |
12 |
85,076,107 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1945:Ylpm1
|
UTSW |
12 |
85,062,192 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1971:Ylpm1
|
UTSW |
12 |
85,087,560 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2211:Ylpm1
|
UTSW |
12 |
85,091,152 (GRCm39) |
nonsense |
probably null |
|
|
R2213:Ylpm1
|
UTSW |
12 |
85,116,492 (GRCm39) |
missense |
probably benign |
0.25 |
|
R2269:Ylpm1
|
UTSW |
12 |
85,061,824 (GRCm39) |
missense |
unknown |
|
|
R2300:Ylpm1
|
UTSW |
12 |
85,107,093 (GRCm39) |
splice site |
probably null |
|
|
R2439:Ylpm1
|
UTSW |
12 |
85,060,891 (GRCm39) |
unclassified |
probably benign |
|
|
R2497:Ylpm1
|
UTSW |
12 |
85,043,535 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2890:Ylpm1
|
UTSW |
12 |
85,076,587 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3111:Ylpm1
|
UTSW |
12 |
85,076,145 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3436:Ylpm1
|
UTSW |
12 |
85,096,644 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3437:Ylpm1
|
UTSW |
12 |
85,096,644 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4156:Ylpm1
|
UTSW |
12 |
85,104,177 (GRCm39) |
intron |
probably benign |
|
|
R4157:Ylpm1
|
UTSW |
12 |
85,104,177 (GRCm39) |
intron |
probably benign |
|
|
R4959:Ylpm1
|
UTSW |
12 |
85,096,719 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5014:Ylpm1
|
UTSW |
12 |
85,061,523 (GRCm39) |
missense |
unknown |
|
|
R5039:Ylpm1
|
UTSW |
12 |
85,089,013 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5039:Ylpm1
|
UTSW |
12 |
85,062,267 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5084:Ylpm1
|
UTSW |
12 |
85,076,095 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5325:Ylpm1
|
UTSW |
12 |
85,060,735 (GRCm39) |
unclassified |
probably benign |
|
|
R5378:Ylpm1
|
UTSW |
12 |
85,077,029 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5428:Ylpm1
|
UTSW |
12 |
85,077,003 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5467:Ylpm1
|
UTSW |
12 |
85,043,633 (GRCm39) |
missense |
unknown |
|
|
R5605:Ylpm1
|
UTSW |
12 |
85,075,627 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5614:Ylpm1
|
UTSW |
12 |
85,111,718 (GRCm39) |
intron |
probably benign |
|
|
R5748:Ylpm1
|
UTSW |
12 |
85,107,025 (GRCm39) |
splice site |
probably null |
|
|
R5860:Ylpm1
|
UTSW |
12 |
85,087,660 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5861:Ylpm1
|
UTSW |
12 |
85,087,660 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5881:Ylpm1
|
UTSW |
12 |
85,088,899 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5909:Ylpm1
|
UTSW |
12 |
85,087,660 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5912:Ylpm1
|
UTSW |
12 |
85,087,660 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5915:Ylpm1
|
UTSW |
12 |
85,087,660 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6000:Ylpm1
|
UTSW |
12 |
85,044,030 (GRCm39) |
missense |
unknown |
|
|
R6004:Ylpm1
|
UTSW |
12 |
85,075,858 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R6007:Ylpm1
|
UTSW |
12 |
85,076,064 (GRCm39) |
missense |
probably benign |
0.33 |
|
R6053:Ylpm1
|
UTSW |
12 |
85,043,277 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R6104:Ylpm1
|
UTSW |
12 |
85,076,404 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6197:Ylpm1
|
UTSW |
12 |
85,088,953 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6293:Ylpm1
|
UTSW |
12 |
85,062,051 (GRCm39) |
missense |
unknown |
|
|
R6297:Ylpm1
|
UTSW |
12 |
85,062,051 (GRCm39) |
missense |
unknown |
|
|
R6305:Ylpm1
|
UTSW |
12 |
85,077,319 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6379:Ylpm1
|
UTSW |
12 |
85,077,574 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6465:Ylpm1
|
UTSW |
12 |
85,096,576 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6608:Ylpm1
|
UTSW |
12 |
85,062,051 (GRCm39) |
missense |
unknown |
|
|
R6609:Ylpm1
|
UTSW |
12 |
85,062,051 (GRCm39) |
missense |
unknown |
|
|
R6737:Ylpm1
|
UTSW |
12 |
85,077,620 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6794:Ylpm1
|
UTSW |
12 |
85,043,655 (GRCm39) |
missense |
unknown |
|
|
R7383:Ylpm1
|
UTSW |
12 |
85,091,242 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7514:Ylpm1
|
UTSW |
12 |
85,077,268 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7577:Ylpm1
|
UTSW |
12 |
85,043,994 (GRCm39) |
missense |
unknown |
|
|
R7709:Ylpm1
|
UTSW |
12 |
85,059,799 (GRCm39) |
missense |
unknown |
|
|
R7718:Ylpm1
|
UTSW |
12 |
85,075,896 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7736:Ylpm1
|
UTSW |
12 |
85,059,757 (GRCm39) |
missense |
unknown |
|
|
R7758:Ylpm1
|
UTSW |
12 |
85,061,796 (GRCm39) |
missense |
unknown |
|
|
R7807:Ylpm1
|
UTSW |
12 |
85,060,855 (GRCm39) |
nonsense |
probably null |
|
|
R7838:Ylpm1
|
UTSW |
12 |
85,095,640 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7846:Ylpm1
|
UTSW |
12 |
85,104,042 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8170:Ylpm1
|
UTSW |
12 |
85,080,801 (GRCm39) |
missense |
probably benign |
0.40 |
|
R8776:Ylpm1
|
UTSW |
12 |
85,077,195 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8776-TAIL:Ylpm1
|
UTSW |
12 |
85,077,195 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8812:Ylpm1
|
UTSW |
12 |
85,043,566 (GRCm39) |
missense |
unknown |
|
|
R8847:Ylpm1
|
UTSW |
12 |
85,061,672 (GRCm39) |
missense |
unknown |
|
|
R8874:Ylpm1
|
UTSW |
12 |
85,116,394 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9129:Ylpm1
|
UTSW |
12 |
85,104,052 (GRCm39) |
missense |
|
|
|
R9165:Ylpm1
|
UTSW |
12 |
85,077,342 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9198:Ylpm1
|
UTSW |
12 |
85,080,689 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R9564:Ylpm1
|
UTSW |
12 |
85,091,176 (GRCm39) |
missense |
probably benign |
0.30 |
|
R9629:Ylpm1
|
UTSW |
12 |
85,044,036 (GRCm39) |
missense |
unknown |
|
|
R9797:Ylpm1
|
UTSW |
12 |
85,077,109 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
Z1088:Ylpm1
|
UTSW |
12 |
85,076,929 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
Z1176:Ylpm1
|
UTSW |
12 |
85,077,058 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
Z1177:Ylpm1
|
UTSW |
12 |
85,104,057 (GRCm39) |
missense |
probably damaging |
0.98 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGTCTTCTGGACACAAACTTTGGTGC -3'
(R):5'- TCTTGCCACAAGTCTGGTTATCAGC -3'
Sequencing Primer
(F):5'- CTTAGGTGGGAAGAAGAGGATGC -3'
(R):5'- GGTTATCAGCACTCATTTCAGC -3'
|
| Posted On |
2013-05-09 |
Incidental Mutation