Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01621:Dync2h1'

92623

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Dync2h1

Ensembl Gene

ENSMUSG00000047193

Gene Name

dynein cytoplasmic 2 heavy chain 1

Synonyms

4432416O06Rik, DHC2, D030010H02Rik, D330044F14Rik, Dnchc2, DHC1b, b2b414Clo

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

IGL01621

Quality Score

Status

Chromosome

Chromosomal Location

6928503-7184446 bp(-) (GRCm38)

Type of Mutation

critical splice donor site (2 bp from exon)

DNA Base Change (assembly)

A to G at 7140897 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000116679 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000048417] [ENSMUST00000140466] [ENSMUST00000147193]

AlphaFold

no structure available at present

Predicted Effect

probably null
Transcript: ENSMUST00000048417

SMART Domains

Protein: ENSMUSP00000046733
Gene: ENSMUSG00000047193

Domain	Start	End	E-Value	Type
Pfam:DHC_N1	187	676	1.6e-43	PFAM
Pfam:DHC_N2	1117	1523	4.1e-120	PFAM
AAA	1684	1830	3.72e-2	SMART
AAA	1971	2127	2.18e0	SMART
AAA	2283	2431	1.66e0	SMART
low complexity region	2588	2602	N/A	INTRINSIC
Pfam:AAA_8	2618	2881	6.8e-27	PFAM
Pfam:MT	2894	3230	5.4e-28	PFAM
Pfam:AAA_9	3242	3471	1.1e-50	PFAM
Pfam:Dynein_heavy	3605	4304	2.3e-136	PFAM

Predicted Effect

probably null
Transcript: ENSMUST00000140466

SMART Domains

Protein: ENSMUSP00000120007
Gene: ENSMUSG00000047193

Domain	Start	End	E-Value	Type
Pfam:DHC_N1	187	676	1.6e-43	PFAM
Pfam:DHC_N2	1117	1523	4.1e-120	PFAM
AAA	1684	1830	3.72e-2	SMART
AAA	1971	2127	2.18e0	SMART
AAA	2283	2431	1.66e0	SMART
low complexity region	2588	2602	N/A	INTRINSIC
Pfam:AAA_8	2618	2881	6.8e-27	PFAM
Pfam:MT	2894	3230	5.4e-28	PFAM
Pfam:AAA_9	3242	3471	1.1e-50	PFAM
Pfam:Dynein_heavy	3605	4304	2.3e-136	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000147056

Predicted Effect

probably null
Transcript: ENSMUST00000147193

SMART Domains

Protein: ENSMUSP00000116679
Gene: ENSMUSG00000047193

Domain	Start	End	E-Value	Type
Pfam:DHC_N1	188	674	4e-45	PFAM
Pfam:DHC_N2	1118	1521	5.5e-111	PFAM
AAA	1684	1830	3.72e-2	SMART
AAA	1971	2127	2.18e0	SMART
AAA	2283	2431	1.66e0	SMART
low complexity region	2588	2602	N/A	INTRINSIC
Pfam:AAA_8	2618	2880	4.4e-27	PFAM
Pfam:MT	2894	3230	1.3e-27	PFAM
Pfam:AAA_9	3246	3477	1e-79	PFAM
Pfam:Dynein_heavy	3618	4310	8.5e-158	PFAM

Coding Region Coverage

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a large cytoplasmic dynein protein that is involved in retrograde transport in the cilium and has a role in intraflagellar transport, a process required for ciliary/flagellar assembly. Mutations in this gene cause a heterogeneous spectrum of conditions related to altered primary cilium function and often involve polydactyly, abnormal skeletogenesis, and polycystic kidneys. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jan 2010]
PHENOTYPE: Homozygotes for a gene trap allele show complete embryonic lethality with altered heart looping and brain morphology. Chemically induced mutants show randomized heart looping and polydactyly. Holoprosencephaly or exencephaly, micrognathia, and cardiac, renal, airway and eye defects may be observed. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 71 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
0610040J01Rik	C	T	5: 63,898,383	T154I	possibly damaging	Het
4933434E20Rik	T	A	3: 90,064,502	M56K	possibly damaging	Het
5730559C18Rik	C	A	1: 136,219,775	A402S	probably damaging	Het
A730017C20Rik	A	G	18: 59,062,386	M1V	probably null	Het
Abca6	A	G	11: 110,184,708	L1319S	probably damaging	Het
Adh4	C	T	3: 138,429,027		probably benign	Het
Aloxe3	A	G	11: 69,130,013	N188S	probably benign	Het
Ap1s1	G	A	5: 137,041,804	R119*	probably null	Het
Apc2	T	G	10: 80,306,201	L318R	probably damaging	Het
Atg101	A	G	15: 101,287,095	S33G	possibly damaging	Het
Atp8a2	A	T	14: 60,015,868		probably benign	Het
Bpifb9b	C	A	2: 154,316,951		probably null	Het
Braf	A	T	6: 39,646,853		probably benign	Het
Cabp5	A	G	7: 13,401,264	D43G	probably damaging	Het
Cfap46	T	C	7: 139,606,607	N2462S	unknown	Het
Cit	C	T	5: 115,992,603		probably benign	Het
Cpa4	T	C	6: 30,574,416	V68A	probably damaging	Het
Cyp2j5	T	C	4: 96,629,554	I474V	probably benign	Het
Dennd1a	C	A	2: 37,844,809	D49Y	probably damaging	Het
Dlg5	T	C	14: 24,148,221	D1525G	probably damaging	Het
Dnajc18	C	T	18: 35,680,840	R292H	probably benign	Het
E2f6	A	G	12: 16,825,368	D268G	probably benign	Het
Evi2b	T	A	11: 79,516,300	T150S	probably damaging	Het
F13b	A	G	1: 139,503,851	D53G	probably benign	Het
Fbxo38	G	A	18: 62,522,524		probably benign	Het
Flnb	C	T	14: 7,950,470	P2596L	probably damaging	Het
Fyco1	A	G	9: 123,827,182		probably benign	Het
Gm13023	T	C	4: 143,793,932	F85L	probably benign	Het
Gm21759	A	G	5: 8,179,775		probably benign	Het
Gtse1	A	G	15: 85,875,082	N597S	probably benign	Het
Hcn3	G	T	3: 89,147,723	S739Y	probably damaging	Het
Ighv9-4	T	A	12: 114,299,992	N107I	probably damaging	Het
Iqub	T	C	6: 24,446,212	K738E	probably benign	Het
Itga6	A	T	2: 71,825,656	D308V	probably benign	Het
Klf12	T	C	14: 100,023,149	Y48C	probably damaging	Het
Klhdc9	A	G	1: 171,358,816	*351Q	probably null	Het
Krt40	A	T	11: 99,542,868	N97K	probably damaging	Het
Lrit1	A	C	14: 37,060,155	T262P	probably damaging	Het
Mcoln1	T	C	8: 3,510,910	Y411H	probably damaging	Het
Mfsd4a	A	G	1: 132,054,143	S149P	probably benign	Het
Mipep	A	G	14: 60,796,165		probably benign	Het
Mslnl	A	G	17: 25,743,667		probably benign	Het
N4bp2	A	T	5: 65,790,924	H299L	probably damaging	Het
Nbn	C	T	4: 15,965,221	P190S	probably benign	Het
Nos1	T	A	5: 117,945,884	I1253N	probably damaging	Het
Nup210	G	T	6: 91,030,117	F572L	probably damaging	Het
Olfr1381	T	C	11: 49,552,137	L130P	probably damaging	Het
Olfr370	T	C	8: 83,541,618	V158A	probably benign	Het
Olfr390	T	C	11: 73,787,277	F113S	probably damaging	Het
P4htm	T	A	9: 108,583,736	E106V	probably damaging	Het
Pcdhb20	C	T	18: 37,504,807	H129Y	possibly damaging	Het
Pdcd6ip	T	C	9: 113,685,422	E240G	probably benign	Het
Pex5l	T	C	3: 33,014,961		probably null	Het
Plcd1	T	C	9: 119,076,178	N181S	probably damaging	Het
Plekhg6	G	T	6: 125,372,099	L412M	probably damaging	Het
Ppp1r13b	T	A	12: 111,835,092	Q386L	possibly damaging	Het
Prpf40b	A	G	15: 99,310,045		probably benign	Het
Rdh11	C	T	12: 79,186,413		probably null	Het
Ripor3	A	T	2: 167,997,252	S110T	probably damaging	Het
Sec24d	G	A	3: 123,294,158		probably null	Het
Secisbp2l	T	C	2: 125,773,211	S165G	probably benign	Het
Shank1	C	T	7: 44,342,465	A698V	unknown	Het
Shank1	T	C	7: 44,351,599	M914T	unknown	Het
Slc22a3	T	C	17: 12,458,492	Q263R	probably benign	Het
Smc1a	C	A	X: 152,036,129	Q647K	probably damaging	Het
Sohlh1	A	G	2: 25,846,861		probably benign	Het
Tacc2	C	A	7: 130,729,768	T484K	probably damaging	Het
Ubr4	G	T	4: 139,440,783	E2825*	probably null	Het
Wbp2nl	G	A	15: 82,308,605	M163I	probably benign	Het
Zfp69	T	A	4: 120,931,500	K206M	probably damaging	Het
Zswim3	G	A	2: 164,821,520	R640H	probably damaging	Het

Other mutations in Dync2h1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00159:Dync2h1	APN	9	7,158,839 (GRCm38)	missense	probably benign	0.42
IGL00310:Dync2h1	APN	9	7,155,072 (GRCm38)	splice site	probably benign
IGL00499:Dync2h1	APN	9	7,168,700 (GRCm38)	missense	possibly damaging	0.95
IGL00579:Dync2h1	APN	9	7,035,728 (GRCm38)	splice site	probably benign
IGL00660:Dync2h1	APN	9	7,075,797 (GRCm38)	missense	probably damaging	0.98
IGL00964:Dync2h1	APN	9	7,174,881 (GRCm38)	splice site	probably benign
IGL01025:Dync2h1	APN	9	7,162,789 (GRCm38)	missense	probably damaging	1.00
IGL01093:Dync2h1	APN	9	7,145,611 (GRCm38)	missense	probably benign	0.01
IGL01108:Dync2h1	APN	9	7,176,771 (GRCm38)	missense	possibly damaging	0.87
IGL01126:Dync2h1	APN	9	7,116,588 (GRCm38)	missense	probably benign	0.00
IGL01474:Dync2h1	APN	9	7,102,493 (GRCm38)	missense	probably benign	0.01
IGL01531:Dync2h1	APN	9	7,071,111 (GRCm38)	missense	probably benign	0.11
IGL01548:Dync2h1	APN	9	7,071,922 (GRCm38)	missense	probably damaging	1.00
IGL01672:Dync2h1	APN	9	7,118,884 (GRCm38)	nonsense	probably null
IGL01681:Dync2h1	APN	9	7,142,196 (GRCm38)	splice site	probably null
IGL01685:Dync2h1	APN	9	7,142,297 (GRCm38)	missense	probably damaging	1.00
IGL01724:Dync2h1	APN	9	7,081,077 (GRCm38)	missense	probably benign	0.03
IGL01738:Dync2h1	APN	9	7,114,922 (GRCm38)	missense	possibly damaging	0.77
IGL01783:Dync2h1	APN	9	7,118,822 (GRCm38)	unclassified	probably benign
IGL01813:Dync2h1	APN	9	7,122,799 (GRCm38)	missense	probably damaging	1.00
IGL01931:Dync2h1	APN	9	7,114,973 (GRCm38)	missense	probably damaging	1.00
IGL01931:Dync2h1	APN	9	7,011,207 (GRCm38)	missense	probably benign	0.33
IGL02105:Dync2h1	APN	9	7,075,892 (GRCm38)	missense	probably damaging	1.00
IGL02137:Dync2h1	APN	9	7,134,349 (GRCm38)	missense	probably benign
IGL02140:Dync2h1	APN	9	7,147,791 (GRCm38)	missense	probably benign
IGL02175:Dync2h1	APN	9	7,111,548 (GRCm38)	missense	possibly damaging	0.91
IGL02283:Dync2h1	APN	9	7,125,912 (GRCm38)	missense	probably damaging	0.99
IGL02305:Dync2h1	APN	9	7,122,678 (GRCm38)	missense	probably benign
IGL02342:Dync2h1	APN	9	7,142,246 (GRCm38)	missense	probably damaging	1.00
IGL02367:Dync2h1	APN	9	7,158,926 (GRCm38)	missense	probably damaging	0.98
IGL02458:Dync2h1	APN	9	7,117,422 (GRCm38)	missense	probably damaging	1.00
IGL02563:Dync2h1	APN	9	7,035,700 (GRCm38)	missense	possibly damaging	0.95
IGL02825:Dync2h1	APN	9	6,955,901 (GRCm38)	splice site	probably benign
IGL02955:Dync2h1	APN	9	7,142,864 (GRCm38)	missense	probably benign	0.00
IGL02992:Dync2h1	APN	9	7,137,074 (GRCm38)	missense	probably benign	0.01
IGL02996:Dync2h1	APN	9	6,935,279 (GRCm38)	missense	probably damaging	0.99
IGL03224:Dync2h1	APN	9	7,076,235 (GRCm38)	missense	probably benign	0.32
IGL03226:Dync2h1	APN	9	7,125,918 (GRCm38)	missense	probably benign
IGL03233:Dync2h1	APN	9	7,101,525 (GRCm38)	missense	possibly damaging	0.90
deinonychus	UTSW	9	7,159,478 (GRCm38)	splice site	probably null
R0016:Dync2h1	UTSW	9	7,144,346 (GRCm38)	splice site	probably benign
R0016:Dync2h1	UTSW	9	7,144,346 (GRCm38)	splice site	probably benign
R0043:Dync2h1	UTSW	9	7,005,574 (GRCm38)	missense	probably benign	0.05
R0109:Dync2h1	UTSW	9	7,111,487 (GRCm38)	missense	probably damaging	1.00
R0109:Dync2h1	UTSW	9	7,111,487 (GRCm38)	missense	probably damaging	1.00
R0121:Dync2h1	UTSW	9	7,001,327 (GRCm38)	splice site	probably benign
R0277:Dync2h1	UTSW	9	7,129,046 (GRCm38)	missense	probably benign
R0360:Dync2h1	UTSW	9	7,113,182 (GRCm38)	missense	possibly damaging	0.62
R0362:Dync2h1	UTSW	9	7,005,487 (GRCm38)	splice site	probably null
R0389:Dync2h1	UTSW	9	7,167,244 (GRCm38)	splice site	probably null
R0443:Dync2h1	UTSW	9	7,167,244 (GRCm38)	splice site	probably null
R0496:Dync2h1	UTSW	9	7,155,180 (GRCm38)	missense	probably benign	0.42
R0506:Dync2h1	UTSW	9	7,113,153 (GRCm38)	missense	probably benign	0.05
R0511:Dync2h1	UTSW	9	7,122,692 (GRCm38)	missense	probably benign	0.00
R0540:Dync2h1	UTSW	9	7,051,480 (GRCm38)	missense	probably benign	0.00
R0550:Dync2h1	UTSW	9	7,120,954 (GRCm38)	splice site	probably null
R0564:Dync2h1	UTSW	9	7,139,432 (GRCm38)	missense	probably damaging	1.00
R0607:Dync2h1	UTSW	9	7,051,480 (GRCm38)	missense	probably benign	0.00
R0699:Dync2h1	UTSW	9	7,103,680 (GRCm38)	missense	probably benign	0.00
R0725:Dync2h1	UTSW	9	7,015,497 (GRCm38)	missense	possibly damaging	0.93
R0835:Dync2h1	UTSW	9	7,116,642 (GRCm38)	critical splice acceptor site	probably null
R0837:Dync2h1	UTSW	9	7,077,979 (GRCm38)	missense	probably benign	0.07
R0894:Dync2h1	UTSW	9	7,041,734 (GRCm38)	splice site	probably benign
R0938:Dync2h1	UTSW	9	7,002,658 (GRCm38)	missense	probably benign	0.02
R1056:Dync2h1	UTSW	9	7,147,731 (GRCm38)	missense	probably benign	0.15
R1081:Dync2h1	UTSW	9	7,005,488 (GRCm38)	critical splice donor site	probably null
R1178:Dync2h1	UTSW	9	7,101,193 (GRCm38)	splice site	probably benign
R1243:Dync2h1	UTSW	9	7,120,882 (GRCm38)	missense	probably benign
R1295:Dync2h1	UTSW	9	7,075,752 (GRCm38)	splice site	probably benign
R1304:Dync2h1	UTSW	9	7,102,318 (GRCm38)	missense	probably damaging	1.00
R1387:Dync2h1	UTSW	9	7,125,816 (GRCm38)	missense	probably benign
R1513:Dync2h1	UTSW	9	7,103,663 (GRCm38)	missense	possibly damaging	0.74
R1557:Dync2h1	UTSW	9	7,140,911 (GRCm38)	missense	probably damaging	1.00
R1568:Dync2h1	UTSW	9	7,157,553 (GRCm38)	missense	probably null	0.02
R1570:Dync2h1	UTSW	9	7,176,926 (GRCm38)	missense	probably benign	0.12
R1670:Dync2h1	UTSW	9	6,993,942 (GRCm38)	missense	possibly damaging	0.82
R1713:Dync2h1	UTSW	9	7,131,891 (GRCm38)	missense	probably benign
R1766:Dync2h1	UTSW	9	7,015,526 (GRCm38)	critical splice acceptor site	probably null
R1773:Dync2h1	UTSW	9	7,128,256 (GRCm38)	missense	probably damaging	1.00
R1786:Dync2h1	UTSW	9	7,081,084 (GRCm38)	missense	probably damaging	1.00
R1848:Dync2h1	UTSW	9	7,049,166 (GRCm38)	missense	probably benign	0.01
R1850:Dync2h1	UTSW	9	7,001,448 (GRCm38)	missense	probably benign	0.00
R1935:Dync2h1	UTSW	9	7,139,159 (GRCm38)	critical splice donor site	probably null
R1936:Dync2h1	UTSW	9	7,139,159 (GRCm38)	critical splice donor site	probably null
R1937:Dync2h1	UTSW	9	7,139,159 (GRCm38)	critical splice donor site	probably null
R1939:Dync2h1	UTSW	9	7,139,159 (GRCm38)	critical splice donor site	probably null
R1940:Dync2h1	UTSW	9	7,139,159 (GRCm38)	critical splice donor site	probably null
R1944:Dync2h1	UTSW	9	7,001,377 (GRCm38)	missense	probably damaging	1.00
R1976:Dync2h1	UTSW	9	7,129,045 (GRCm38)	missense	probably benign
R2012:Dync2h1	UTSW	9	7,169,589 (GRCm38)	missense	probably benign	0.00
R2020:Dync2h1	UTSW	9	7,162,925 (GRCm38)	missense	probably benign	0.25
R2020:Dync2h1	UTSW	9	7,122,772 (GRCm38)	missense	probably damaging	0.99
R2024:Dync2h1	UTSW	9	7,129,062 (GRCm38)	missense	probably damaging	0.97
R2038:Dync2h1	UTSW	9	6,967,226 (GRCm38)	missense	probably damaging	0.99
R2045:Dync2h1	UTSW	9	7,160,171 (GRCm38)	missense	probably damaging	1.00
R2060:Dync2h1	UTSW	9	7,162,802 (GRCm38)	missense	possibly damaging	0.92
R2094:Dync2h1	UTSW	9	7,148,735 (GRCm38)	missense	probably benign	0.18
R2129:Dync2h1	UTSW	9	7,175,289 (GRCm38)	missense	possibly damaging	0.94
R2130:Dync2h1	UTSW	9	7,011,253 (GRCm38)	missense	probably damaging	1.00
R2136:Dync2h1	UTSW	9	7,122,772 (GRCm38)	missense	probably damaging	0.99
R2164:Dync2h1	UTSW	9	7,124,797 (GRCm38)	missense	probably damaging	1.00
R2242:Dync2h1	UTSW	9	7,037,828 (GRCm38)	splice site	probably null
R2255:Dync2h1	UTSW	9	6,955,905 (GRCm38)	critical splice donor site	probably null
R2357:Dync2h1	UTSW	9	7,081,053 (GRCm38)	missense	probably benign	0.03
R2389:Dync2h1	UTSW	9	7,122,618 (GRCm38)	missense	possibly damaging	0.82
R2412:Dync2h1	UTSW	9	7,144,246 (GRCm38)	missense	probably benign	0.01
R2885:Dync2h1	UTSW	9	7,102,329 (GRCm38)	missense	probably damaging	1.00
R2909:Dync2h1	UTSW	9	7,049,114 (GRCm38)	missense	probably damaging	1.00
R3434:Dync2h1	UTSW	9	7,011,236 (GRCm38)	missense	probably benign
R3719:Dync2h1	UTSW	9	7,006,882 (GRCm38)	splice site	probably benign
R3723:Dync2h1	UTSW	9	7,041,658 (GRCm38)	missense	probably benign	0.17
R3800:Dync2h1	UTSW	9	7,101,525 (GRCm38)	missense	possibly damaging	0.90
R3803:Dync2h1	UTSW	9	6,935,293 (GRCm38)	missense	probably benign	0.00
R3936:Dync2h1	UTSW	9	7,001,482 (GRCm38)	missense	probably damaging	1.00
R3941:Dync2h1	UTSW	9	7,124,825 (GRCm38)	missense	probably benign
R3950:Dync2h1	UTSW	9	7,112,061 (GRCm38)	nonsense	probably null
R4004:Dync2h1	UTSW	9	7,117,404 (GRCm38)	missense	probably damaging	1.00
R4091:Dync2h1	UTSW	9	7,131,881 (GRCm38)	missense	probably benign	0.01
R4233:Dync2h1	UTSW	9	7,134,360 (GRCm38)	missense	probably benign	0.02
R4302:Dync2h1	UTSW	9	7,077,880 (GRCm38)	missense	probably benign	0.02
R4451:Dync2h1	UTSW	9	6,983,477 (GRCm38)	missense	probably benign	0.02
R4512:Dync2h1	UTSW	9	7,085,009 (GRCm38)	nonsense	probably null
R4596:Dync2h1	UTSW	9	6,992,595 (GRCm38)	missense	probably benign
R4604:Dync2h1	UTSW	9	7,140,995 (GRCm38)	missense	probably benign	0.00
R4614:Dync2h1	UTSW	9	7,011,290 (GRCm38)	missense	probably benign	0.03
R4667:Dync2h1	UTSW	9	7,051,411 (GRCm38)	missense	probably benign	0.00
R4671:Dync2h1	UTSW	9	7,169,640 (GRCm38)	missense	possibly damaging	0.82
R4714:Dync2h1	UTSW	9	7,118,932 (GRCm38)	missense	possibly damaging	0.86
R4716:Dync2h1	UTSW	9	7,142,648 (GRCm38)	critical splice donor site	probably null
R4736:Dync2h1	UTSW	9	7,006,862 (GRCm38)	missense	probably benign	0.00
R4807:Dync2h1	UTSW	9	7,139,422 (GRCm38)	missense	probably benign	0.31
R4850:Dync2h1	UTSW	9	7,134,364 (GRCm38)	missense	probably benign	0.14
R4862:Dync2h1	UTSW	9	7,147,717 (GRCm38)	missense	probably benign
R4899:Dync2h1	UTSW	9	7,131,921 (GRCm38)	nonsense	probably null
R4971:Dync2h1	UTSW	9	7,131,949 (GRCm38)	missense	probably benign
R5040:Dync2h1	UTSW	9	6,992,625 (GRCm38)	missense	probably benign	0.09
R5054:Dync2h1	UTSW	9	7,085,007 (GRCm38)	missense	possibly damaging	0.63
R5274:Dync2h1	UTSW	9	7,116,540 (GRCm38)	missense	probably benign	0.00
R5307:Dync2h1	UTSW	9	7,155,099 (GRCm38)	missense	probably damaging	1.00
R5347:Dync2h1	UTSW	9	7,129,727 (GRCm38)	missense	probably damaging	1.00
R5372:Dync2h1	UTSW	9	7,176,962 (GRCm38)	unclassified	probably benign
R5384:Dync2h1	UTSW	9	7,016,791 (GRCm38)	missense	probably damaging	0.99
R5385:Dync2h1	UTSW	9	7,016,791 (GRCm38)	missense	probably damaging	0.99
R5394:Dync2h1	UTSW	9	7,120,899 (GRCm38)	nonsense	probably null
R5402:Dync2h1	UTSW	9	7,114,949 (GRCm38)	missense	probably damaging	1.00
R5446:Dync2h1	UTSW	9	7,144,217 (GRCm38)	missense	probably benign
R5538:Dync2h1	UTSW	9	7,168,630 (GRCm38)	intron	probably benign
R5551:Dync2h1	UTSW	9	7,031,718 (GRCm38)	missense	possibly damaging	0.74
R5619:Dync2h1	UTSW	9	7,118,885 (GRCm38)	missense	probably benign	0.02
R5621:Dync2h1	UTSW	9	7,120,909 (GRCm38)	missense	possibly damaging	0.86
R5652:Dync2h1	UTSW	9	7,116,638 (GRCm38)	missense	probably benign	0.45
R5655:Dync2h1	UTSW	9	7,148,659 (GRCm38)	missense	probably benign	0.01
R5689:Dync2h1	UTSW	9	7,169,689 (GRCm38)	missense	probably damaging	1.00
R5725:Dync2h1	UTSW	9	7,169,528 (GRCm38)	missense	probably benign	0.21
R5742:Dync2h1	UTSW	9	7,165,762 (GRCm38)	missense	possibly damaging	0.64
R5817:Dync2h1	UTSW	9	6,996,905 (GRCm38)	missense	probably damaging	1.00
R5852:Dync2h1	UTSW	9	7,011,290 (GRCm38)	missense	probably benign	0.03
R5898:Dync2h1	UTSW	9	7,148,717 (GRCm38)	missense	probably benign	0.00
R5916:Dync2h1	UTSW	9	7,102,309 (GRCm38)	critical splice donor site	probably null
R5939:Dync2h1	UTSW	9	7,037,801 (GRCm38)	missense	probably damaging	0.99
R5942:Dync2h1	UTSW	9	7,117,466 (GRCm38)	nonsense	probably null
R5982:Dync2h1	UTSW	9	6,955,986 (GRCm38)	missense	probably benign	0.00
R6029:Dync2h1	UTSW	9	7,157,646 (GRCm38)	missense	probably benign
R6125:Dync2h1	UTSW	9	7,168,706 (GRCm38)	missense	probably damaging	1.00
R6209:Dync2h1	UTSW	9	7,165,677 (GRCm38)	missense	probably benign	0.01
R6247:Dync2h1	UTSW	9	7,135,078 (GRCm38)	missense	probably damaging	1.00
R6294:Dync2h1	UTSW	9	7,084,986 (GRCm38)	missense	probably benign	0.01
R6328:Dync2h1	UTSW	9	7,165,717 (GRCm38)	missense	probably benign	0.00
R6376:Dync2h1	UTSW	9	7,165,703 (GRCm38)	missense	probably benign	0.21
R6394:Dync2h1	UTSW	9	7,168,331 (GRCm38)	missense	probably damaging	0.99
R6539:Dync2h1	UTSW	9	7,159,478 (GRCm38)	splice site	probably null
R6554:Dync2h1	UTSW	9	7,037,699 (GRCm38)	missense	probably benign	0.39
R6559:Dync2h1	UTSW	9	7,139,501 (GRCm38)	missense	possibly damaging	0.72
R6563:Dync2h1	UTSW	9	7,120,819 (GRCm38)	missense	probably benign	0.27
R6807:Dync2h1	UTSW	9	7,041,718 (GRCm38)	missense	probably benign	0.10
R6848:Dync2h1	UTSW	9	7,159,632 (GRCm38)	missense	probably benign	0.22
R6901:Dync2h1	UTSW	9	7,131,855 (GRCm38)	missense	probably damaging	1.00
R6921:Dync2h1	UTSW	9	7,102,549 (GRCm38)	missense	probably benign
R6997:Dync2h1	UTSW	9	7,168,743 (GRCm38)	missense	probably null	0.00
R7084:Dync2h1	UTSW	9	7,113,214 (GRCm38)	missense	possibly damaging	0.72
R7113:Dync2h1	UTSW	9	7,075,788 (GRCm38)	missense	probably benign	0.03
R7131:Dync2h1	UTSW	9	7,075,786 (GRCm38)	missense	probably damaging	1.00
R7165:Dync2h1	UTSW	9	7,050,479 (GRCm38)	missense	probably benign
R7196:Dync2h1	UTSW	9	7,147,715 (GRCm38)	nonsense	probably null
R7208:Dync2h1	UTSW	9	7,141,059 (GRCm38)	missense	probably damaging	1.00
R7225:Dync2h1	UTSW	9	7,142,756 (GRCm38)	missense	probably benign
R7237:Dync2h1	UTSW	9	6,993,966 (GRCm38)	missense	probably benign	0.00
R7243:Dync2h1	UTSW	9	7,102,405 (GRCm38)	missense	possibly damaging	0.64
R7291:Dync2h1	UTSW	9	6,929,590 (GRCm38)	missense	possibly damaging	0.69
R7293:Dync2h1	UTSW	9	7,001,454 (GRCm38)	missense	possibly damaging	0.88
R7329:Dync2h1	UTSW	9	7,011,247 (GRCm38)	missense	probably benign
R7351:Dync2h1	UTSW	9	7,167,145 (GRCm38)	missense	probably damaging	1.00
R7358:Dync2h1	UTSW	9	7,159,479 (GRCm38)	critical splice donor site	probably null
R7387:Dync2h1	UTSW	9	7,157,932 (GRCm38)	missense	possibly damaging	0.68
R7446:Dync2h1	UTSW	9	7,041,720 (GRCm38)	missense	probably benign	0.03
R7487:Dync2h1	UTSW	9	7,132,041 (GRCm38)	missense	probably benign	0.26
R7488:Dync2h1	UTSW	9	7,124,855 (GRCm38)	missense	probably benign	0.03
R7496:Dync2h1	UTSW	9	7,135,015 (GRCm38)	splice site	probably null
R7501:Dync2h1	UTSW	9	7,175,336 (GRCm38)	missense	possibly damaging	0.82
R7571:Dync2h1	UTSW	9	7,002,623 (GRCm38)	missense	probably damaging	1.00
R7627:Dync2h1	UTSW	9	7,101,111 (GRCm38)	missense	probably benign	0.00
R7639:Dync2h1	UTSW	9	7,141,254 (GRCm38)	missense	probably damaging	0.97
R7653:Dync2h1	UTSW	9	7,117,570 (GRCm38)	missense	probably benign
R7654:Dync2h1	UTSW	9	7,122,664 (GRCm38)	missense	probably damaging	1.00
R7742:Dync2h1	UTSW	9	7,076,232 (GRCm38)	missense	probably benign	0.00
R7755:Dync2h1	UTSW	9	7,015,490 (GRCm38)	missense	probably benign	0.00
R7762:Dync2h1	UTSW	9	7,129,719 (GRCm38)	missense	probably benign	0.01
R7790:Dync2h1	UTSW	9	7,114,914 (GRCm38)	missense	probably damaging	0.96
R7834:Dync2h1	UTSW	9	7,118,953 (GRCm38)	missense	probably benign	0.04
R7883:Dync2h1	UTSW	9	7,005,566 (GRCm38)	missense	possibly damaging	0.80
R7952:Dync2h1	UTSW	9	7,129,802 (GRCm38)	missense	possibly damaging	0.63
R8111:Dync2h1	UTSW	9	7,148,688 (GRCm38)	missense	probably benign	0.03
R8157:Dync2h1	UTSW	9	7,001,473 (GRCm38)	missense	possibly damaging	0.47
R8166:Dync2h1	UTSW	9	7,129,089 (GRCm38)	nonsense	probably null
R8236:Dync2h1	UTSW	9	7,080,363 (GRCm38)	intron	probably benign
R8326:Dync2h1	UTSW	9	7,147,771 (GRCm38)	missense	probably benign
R8335:Dync2h1	UTSW	9	7,084,941 (GRCm38)	missense	probably benign	0.28
R8347:Dync2h1	UTSW	9	7,116,578 (GRCm38)	missense	possibly damaging	0.81
R8372:Dync2h1	UTSW	9	7,111,514 (GRCm38)	missense	possibly damaging	0.90
R8421:Dync2h1	UTSW	9	7,102,477 (GRCm38)	missense	probably damaging	1.00
R8518:Dync2h1	UTSW	9	7,051,452 (GRCm38)	missense	probably benign	0.04
R8556:Dync2h1	UTSW	9	7,113,198 (GRCm38)	missense	probably benign	0.32
R8690:Dync2h1	UTSW	9	7,075,824 (GRCm38)	missense	probably damaging	1.00
R8713:Dync2h1	UTSW	9	7,141,008 (GRCm38)	nonsense	probably null
R8719:Dync2h1	UTSW	9	7,041,641 (GRCm38)	missense	probably benign	0.05
R8732:Dync2h1	UTSW	9	7,168,326 (GRCm38)	missense	probably damaging	1.00
R8744:Dync2h1	UTSW	9	7,011,220 (GRCm38)	nonsense	probably null
R8749:Dync2h1	UTSW	9	7,035,063 (GRCm38)	missense	probably benign	0.32
R8795:Dync2h1	UTSW	9	7,137,087 (GRCm38)	missense	probably benign	0.00
R8853:Dync2h1	UTSW	9	7,117,645 (GRCm38)	missense	possibly damaging	0.94
R8923:Dync2h1	UTSW	9	7,168,515 (GRCm38)	missense	probably benign
R8969:Dync2h1	UTSW	9	7,130,723 (GRCm38)	missense	probably damaging	1.00
R8988:Dync2h1	UTSW	9	7,037,727 (GRCm38)	missense	probably benign	0.00
R8997:Dync2h1	UTSW	9	7,129,003 (GRCm38)	missense	probably benign
R9025:Dync2h1	UTSW	9	7,139,462 (GRCm38)	nonsense	probably null
R9036:Dync2h1	UTSW	9	7,051,495 (GRCm38)	missense	probably damaging	1.00
R9055:Dync2h1	UTSW	9	6,996,641 (GRCm38)	intron	probably benign
R9165:Dync2h1	UTSW	9	7,114,883 (GRCm38)	missense	probably damaging	0.99
R9172:Dync2h1	UTSW	9	7,031,771 (GRCm38)	missense	probably damaging	1.00
R9286:Dync2h1	UTSW	9	6,941,668 (GRCm38)	missense	probably benign	0.01
R9312:Dync2h1	UTSW	9	7,050,413 (GRCm38)	missense	probably damaging	1.00
R9335:Dync2h1	UTSW	9	7,112,149 (GRCm38)	missense	possibly damaging	0.88
R9344:Dync2h1	UTSW	9	7,148,659 (GRCm38)	missense	probably benign	0.01
R9351:Dync2h1	UTSW	9	7,176,911 (GRCm38)	missense	probably damaging	0.98
R9367:Dync2h1	UTSW	9	7,125,730 (GRCm38)	critical splice donor site	probably null
R9613:Dync2h1	UTSW	9	7,075,769 (GRCm38)	missense	probably damaging	0.99
R9650:Dync2h1	UTSW	9	7,174,849 (GRCm38)	missense	possibly damaging	0.83
R9726:Dync2h1	UTSW	9	7,077,999 (GRCm38)	missense	possibly damaging	0.94
R9731:Dync2h1	UTSW	9	7,141,166 (GRCm38)	missense	probably benign
X0009:Dync2h1	UTSW	9	7,117,576 (GRCm38)	missense	possibly damaging	0.81
Z1176:Dync2h1	UTSW	9	7,168,730 (GRCm38)	frame shift	probably null
Z1176:Dync2h1	UTSW	9	7,142,361 (GRCm38)	missense	probably damaging	0.99
Z1177:Dync2h1	UTSW	9	7,102,427 (GRCm38)	missense	probably damaging	1.00

Posted On

2013-12-09