Mutagenetix > Incidental Mutation

Incidental Mutation 'R4788:Abcc9'

367250

Institutional Source

Beutler Lab

Gene Symbol

Abcc9

Ensembl Gene

ENSMUSG00000030249

Gene Name

ATP-binding cassette, sub-family C member 9

Synonyms

SUR2A, Sur2, SUR2B

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.108) question?

Stock #

R4788 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

142533588-142648041 bp(-) (GRCm39)

Type of Mutation

nonsense

DNA Base Change (assembly)

A to T at 142566456 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Cysteine to Stop codon at position 1135 (C1135*)

Ref Sequence

ENSEMBL: ENSMUSP00000144779 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000073173] [ENSMUST00000087527] [ENSMUST00000100827] [ENSMUST00000111771] [ENSMUST00000205202]

AlphaFold

P70170

Predicted Effect

probably null
Transcript: ENSMUST00000073173
AA Change: C1135*

SMART Domains

Protein: ENSMUSP00000072914
Gene: ENSMUSG00000030249
AA Change: C1135*

Domain	Start	End	E-Value	Type
transmembrane domain	28	50	N/A	INTRINSIC
transmembrane domain	71	93	N/A	INTRINSIC
transmembrane domain	103	125	N/A	INTRINSIC
transmembrane domain	137	159	N/A	INTRINSIC
transmembrane domain	169	188	N/A	INTRINSIC
low complexity region	265	276	N/A	INTRINSIC
Pfam:ABC_membrane	297	583	7.7e-33	PFAM
AAA	659	867	3.11e-13	SMART
coiled coil region	881	935	N/A	INTRINSIC
Pfam:ABC_membrane	956	1228	6.6e-35	PFAM
AAA	1300	1502	9.94e-12	SMART

Predicted Effect

probably null
Transcript: ENSMUST00000087527
AA Change: C1170*

SMART Domains

Protein: ENSMUSP00000084805
Gene: ENSMUSG00000030249
AA Change: C1170*

Domain	Start	End	E-Value	Type
transmembrane domain	28	50	N/A	INTRINSIC
transmembrane domain	71	93	N/A	INTRINSIC
transmembrane domain	103	125	N/A	INTRINSIC
transmembrane domain	137	159	N/A	INTRINSIC
transmembrane domain	169	188	N/A	INTRINSIC
low complexity region	265	276	N/A	INTRINSIC
Pfam:ABC_membrane	297	583	8e-33	PFAM
AAA	694	902	3.11e-13	SMART
coiled coil region	916	970	N/A	INTRINSIC
Pfam:ABC_membrane	991	1263	6.8e-35	PFAM
AAA	1335	1537	9.94e-12	SMART

Predicted Effect

probably null
Transcript: ENSMUST00000100827
AA Change: C1170*

SMART Domains

Protein: ENSMUSP00000098390
Gene: ENSMUSG00000030249
AA Change: C1170*

Domain	Start	End	E-Value	Type
transmembrane domain	28	50	N/A	INTRINSIC
transmembrane domain	71	93	N/A	INTRINSIC
transmembrane domain	103	125	N/A	INTRINSIC
transmembrane domain	137	159	N/A	INTRINSIC
transmembrane domain	169	188	N/A	INTRINSIC
low complexity region	265	276	N/A	INTRINSIC
Pfam:ABC_membrane	297	583	7.1e-35	PFAM
AAA	694	902	3.11e-13	SMART
coiled coil region	916	970	N/A	INTRINSIC
Pfam:ABC_membrane	991	1263	5.2e-38	PFAM
AAA	1335	1520	5.13e-14	SMART

Predicted Effect

probably null
Transcript: ENSMUST00000111771
AA Change: C1157*

SMART Domains

Protein: ENSMUSP00000107401
Gene: ENSMUSG00000030249
AA Change: C1157*

Domain	Start	End	E-Value	Type
transmembrane domain	28	50	N/A	INTRINSIC
transmembrane domain	71	93	N/A	INTRINSIC
transmembrane domain	103	125	N/A	INTRINSIC
transmembrane domain	137	159	N/A	INTRINSIC
transmembrane domain	169	188	N/A	INTRINSIC
low complexity region	265	276	N/A	INTRINSIC
Pfam:ABC_membrane	297	583	1.4e-32	PFAM
AAA	694	889	3.77e-12	SMART
coiled coil region	903	957	N/A	INTRINSIC
Pfam:ABC_membrane	978	1250	1.2e-34	PFAM
AAA	1322	1524	9.94e-12	SMART

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000194811

Predicted Effect

probably null
Transcript: ENSMUST00000205202
AA Change: C1135*

SMART Domains

Protein: ENSMUSP00000144779
Gene: ENSMUSG00000030249
AA Change: C1135*

Domain	Start	End	E-Value	Type
transmembrane domain	28	50	N/A	INTRINSIC
transmembrane domain	71	93	N/A	INTRINSIC
transmembrane domain	103	125	N/A	INTRINSIC
transmembrane domain	137	159	N/A	INTRINSIC
transmembrane domain	169	188	N/A	INTRINSIC
low complexity region	265	276	N/A	INTRINSIC
Pfam:ABC_membrane	297	583	6.9e-35	PFAM
AAA	659	867	3.11e-13	SMART
coiled coil region	881	935	N/A	INTRINSIC
Pfam:ABC_membrane	956	1228	5e-38	PFAM
AAA	1300	1502	9.94e-12	SMART

Coding Region Coverage

1x: 98.8%
3x: 98.4%
10x: 96.9%
20x: 94.4%

Validation Efficiency

MGI Phenotype

FUNCTION: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The human protein is thought to form ATP-sensitive potassium channels in cardiac, skeletal, and vascular and non-vascular smooth muscle. Protein structure suggests a role as the drug-binding channel-modulating subunit of the extrapancreatic ATP-sensitive potassium channels. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2015]
PHENOTYPE: Mice homozygous for a null allele display lower serum glucose, enhanced insulin action, growth retardation, hypertension and spontaneous death due to episodic coronary artery vasospasm. Homozygous exon 5 deletion leads to cardiac mitochondrial defects, cardiomyopathy, and early postnatal death. [provided by MGI curators]

Allele List at MGI

All alleles(4) : Targeted(4)

Other mutations in this stock

Total: 68 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca4	G	A	3: 121,960,361 (GRCm39)	D815N	probably damaging	Het
Ap3b1	G	A	13: 94,702,149 (GRCm39)	M1067I	unknown	Het
Arhgap15	T	C	2: 43,638,902 (GRCm39)	M1T	probably null	Het
Boc	T	C	16: 44,320,796 (GRCm39)	D288G	probably damaging	Het
Brsk1	G	T	7: 4,701,954 (GRCm39)		probably null	Het
Cabp1	T	C	5: 115,313,530 (GRCm39)	N226S	probably benign	Het
Capn13	A	T	17: 73,644,427 (GRCm39)	Y367*	probably null	Het
Ccdc191	A	G	16: 43,777,185 (GRCm39)	E632G	probably damaging	Het
Cit	T	C	5: 116,071,565 (GRCm39)	S591P	probably damaging	Het
Ckmt1	T	C	2: 121,190,427 (GRCm39)	V118A	possibly damaging	Het
Cndp2	T	C	18: 84,693,289 (GRCm39)	N157S	probably damaging	Het
Col6a3	A	G	1: 90,700,672 (GRCm39)		probably null	Het
Coq2	A	T	5: 100,805,775 (GRCm39)	V287E	probably damaging	Het
Cpa6	T	C	1: 10,478,502 (GRCm39)	K278R	possibly damaging	Het
Cracdl	A	T	1: 37,670,556 (GRCm39)	I128K	probably damaging	Het
Cybb	C	G	X: 9,316,989 (GRCm39)	D246H	probably benign	Het
Cyp3a25	A	T	5: 145,921,892 (GRCm39)	Y347*	probably null	Het
Dcun1d4	G	T	5: 73,691,971 (GRCm39)	W160L	probably damaging	Het
Dennd4c	A	G	4: 86,738,200 (GRCm39)	T994A	probably benign	Het
Dhx57	T	C	17: 80,582,760 (GRCm39)	T229A	probably benign	Het
Dnah6	T	A	6: 73,106,513 (GRCm39)	R1741S	probably damaging	Het
Dock1	T	A	7: 134,747,213 (GRCm39)	V1508D	probably damaging	Het
Donson	T	C	16: 91,484,721 (GRCm39)	T117A	possibly damaging	Het
Dtnb	A	G	12: 3,822,699 (GRCm39)	D533G	probably damaging	Het
Fcrl5	A	G	3: 87,364,495 (GRCm39)	N470S	probably damaging	Het
Focad	T	A	4: 88,275,706 (GRCm39)	V1105E	unknown	Het
Fry	T	C	5: 150,323,101 (GRCm39)	V1084A	probably benign	Het
Gabra1	G	T	11: 42,037,980 (GRCm39)	R213S	probably damaging	Het
Gbp2b	A	C	3: 142,317,171 (GRCm39)	K509T	probably benign	Het
Gprc6a	T	C	10: 51,491,104 (GRCm39)	T811A	probably benign	Het
Hmgcs2	A	G	3: 98,198,400 (GRCm39)	D101G	probably damaging	Het
Ifna11	G	A	4: 88,738,245 (GRCm39)	W17*	probably null	Het
Ighv1-62-3	T	A	12: 115,424,672 (GRCm39)	M100L	probably benign	Het
Lgmn	T	A	12: 102,368,936 (GRCm39)	Y181F	probably benign	Het
Map4k4	T	C	1: 40,043,076 (GRCm39)	S644P	probably benign	Het
Med9	T	A	11: 59,839,266 (GRCm39)	N58K	probably benign	Het
Nav1	C	T	1: 135,397,461 (GRCm39)	A903T	probably benign	Het
Nop53	T	C	7: 15,676,240 (GRCm39)	E153G	possibly damaging	Het
Nop56	G	T	2: 130,120,820 (GRCm39)	V190L	probably benign	Het
Nyap2	A	T	1: 81,247,112 (GRCm39)	M687L	probably benign	Het
Or4a81	G	A	2: 89,619,480 (GRCm39)	S72F	probably damaging	Het
Or8g17	T	C	9: 38,930,217 (GRCm39)	T207A	probably benign	Het
Or8g26	A	G	9: 39,095,908 (GRCm39)	T145A	probably benign	Het
Osbp2	T	C	11: 3,813,320 (GRCm39)	K183R	probably benign	Het
Pappa2	A	G	1: 158,611,487 (GRCm39)	V1492A	possibly damaging	Het
Pax1	A	G	2: 147,208,124 (GRCm39)	Q244R	possibly damaging	Het
Pcdh9	C	A	14: 94,124,851 (GRCm39)	V317F	probably damaging	Het
Pkhd1l1	A	T	15: 44,361,417 (GRCm39)	Q489L	probably damaging	Het
Poln	A	T	5: 34,286,675 (GRCm39)	S164R	probably benign	Het
Ptf1a	T	C	2: 19,450,762 (GRCm39)	S31P	probably benign	Het
Rasal3	A	T	17: 32,618,312 (GRCm39)	D164E	probably benign	Het
Rnf170	A	G	8: 26,630,891 (GRCm39)	E168G	probably damaging	Het
Rubcn	A	G	16: 32,656,778 (GRCm39)		probably null	Het
Sec16b	A	T	1: 157,389,094 (GRCm39)	T830S	possibly damaging	Het
Sel1l3	A	G	5: 53,289,175 (GRCm39)	V882A	probably benign	Het
Sfpq	A	G	4: 126,919,791 (GRCm39)	E512G	probably damaging	Het
Sh3pxd2a	A	G	19: 47,302,518 (GRCm39)	L187P	probably damaging	Het
Skint6	C	T	4: 113,095,533 (GRCm39)	G42D	possibly damaging	Het
Slc7a2	A	G	8: 41,367,023 (GRCm39)	I526V	probably benign	Het
Spmip7	T	C	11: 11,438,652 (GRCm39)		probably null	Het
Ssh2	A	T	11: 77,320,624 (GRCm39)	N328Y	probably damaging	Het
Taok2	G	A	7: 126,467,304 (GRCm39)	S167L	possibly damaging	Het
Tom1l2	A	G	11: 60,139,844 (GRCm39)	L275P	probably damaging	Het
Trgv5	A	G	13: 19,376,724 (GRCm39)	K57R	probably benign	Het
Tyrp1	C	T	4: 80,763,180 (GRCm39)	R356*	probably null	Het
Zan	A	G	5: 137,440,375 (GRCm39)	L1953P	unknown	Het
Zfhx3	T	C	8: 109,520,842 (GRCm39)	S655P	probably damaging	Het
Zmym1	T	C	4: 126,948,090 (GRCm39)	T94A	probably benign	Het

Other mutations in Abcc9

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00090:Abcc9	APN	6	142,578,916 (GRCm39)	splice site	probably benign
IGL00670:Abcc9	APN	6	142,633,007 (GRCm39)	missense	probably damaging	1.00
IGL00675:Abcc9	APN	6	142,610,347 (GRCm39)	missense	probably damaging	1.00
IGL00741:Abcc9	APN	6	142,632,956 (GRCm39)	missense	probably benign
IGL01371:Abcc9	APN	6	142,602,340 (GRCm39)	missense	probably benign	0.04
IGL01686:Abcc9	APN	6	142,548,801 (GRCm39)	missense	possibly damaging	0.71
IGL01724:Abcc9	APN	6	142,610,259 (GRCm39)	missense	probably benign	0.00
IGL01807:Abcc9	APN	6	142,551,640 (GRCm39)	missense	probably damaging	1.00
IGL01941:Abcc9	APN	6	142,551,630 (GRCm39)	missense	probably damaging	1.00
IGL01946:Abcc9	APN	6	142,571,763 (GRCm39)	missense	probably benign	0.16
IGL02210:Abcc9	APN	6	142,633,097 (GRCm39)	missense	probably damaging	1.00
IGL02498:Abcc9	APN	6	142,617,265 (GRCm39)	critical splice donor site	probably null
IGL02535:Abcc9	APN	6	142,574,152 (GRCm39)	missense	probably benign	0.00
IGL02552:Abcc9	APN	6	142,551,645 (GRCm39)	missense	possibly damaging	0.94
IGL02812:Abcc9	APN	6	142,643,516 (GRCm39)	missense	possibly damaging	0.77
IGL02954:Abcc9	APN	6	142,592,007 (GRCm39)	missense	probably damaging	0.97
IGL03035:Abcc9	APN	6	142,573,319 (GRCm39)	missense	probably damaging	1.00
IGL03040:Abcc9	APN	6	142,598,323 (GRCm39)	nonsense	probably null
IGL03100:Abcc9	APN	6	142,640,270 (GRCm39)	missense	probably damaging	1.00
IGL03157:Abcc9	APN	6	142,551,649 (GRCm39)	splice site	probably benign
R0054:Abcc9	UTSW	6	142,547,500 (GRCm39)	critical splice donor site	probably null
R0054:Abcc9	UTSW	6	142,547,500 (GRCm39)	critical splice donor site	probably null
R0084:Abcc9	UTSW	6	142,604,277 (GRCm39)	missense	probably damaging	0.97
R0211:Abcc9	UTSW	6	142,634,710 (GRCm39)	missense	probably benign	0.01
R0349:Abcc9	UTSW	6	142,610,351 (GRCm39)	missense	probably benign	0.00
R0387:Abcc9	UTSW	6	142,585,230 (GRCm39)	nonsense	probably null
R0393:Abcc9	UTSW	6	142,591,604 (GRCm39)	splice site	probably benign
R0528:Abcc9	UTSW	6	142,638,606 (GRCm39)	missense	probably damaging	1.00
R0588:Abcc9	UTSW	6	142,548,787 (GRCm39)	nonsense	probably null
R0646:Abcc9	UTSW	6	142,627,830 (GRCm39)	missense	probably benign	0.05
R0691:Abcc9	UTSW	6	142,584,979 (GRCm39)	missense	possibly damaging	0.94
R0881:Abcc9	UTSW	6	142,592,029 (GRCm39)	missense	probably damaging	1.00
R1264:Abcc9	UTSW	6	142,592,103 (GRCm39)	splice site	probably benign
R1340:Abcc9	UTSW	6	142,628,581 (GRCm39)	splice site	probably benign
R1413:Abcc9	UTSW	6	142,573,245 (GRCm39)	missense	possibly damaging	0.65
R1413:Abcc9	UTSW	6	142,536,222 (GRCm39)	missense	probably damaging	1.00
R1535:Abcc9	UTSW	6	142,610,361 (GRCm39)	missense	probably damaging	1.00
R1595:Abcc9	UTSW	6	142,578,821 (GRCm39)	missense	probably benign	0.02
R1670:Abcc9	UTSW	6	142,540,448 (GRCm39)	missense	possibly damaging	0.89
R1769:Abcc9	UTSW	6	142,573,194 (GRCm39)	splice site	probably benign
R1888:Abcc9	UTSW	6	142,625,040 (GRCm39)	missense	probably benign
R1888:Abcc9	UTSW	6	142,625,040 (GRCm39)	missense	probably benign
R1918:Abcc9	UTSW	6	142,643,408 (GRCm39)	missense	probably damaging	1.00
R1925:Abcc9	UTSW	6	142,617,333 (GRCm39)	missense	probably damaging	0.98
R2019:Abcc9	UTSW	6	142,621,160 (GRCm39)	missense	probably damaging	1.00
R2698:Abcc9	UTSW	6	142,578,862 (GRCm39)	missense	possibly damaging	0.93
R2860:Abcc9	UTSW	6	142,571,736 (GRCm39)	missense	probably benign	0.01
R2861:Abcc9	UTSW	6	142,571,736 (GRCm39)	missense	probably benign	0.01
R2980:Abcc9	UTSW	6	142,633,034 (GRCm39)	missense	probably benign	0.00
R3115:Abcc9	UTSW	6	142,634,755 (GRCm39)	missense	probably benign	0.08
R3617:Abcc9	UTSW	6	142,625,015 (GRCm39)	missense	probably damaging	0.97
R3880:Abcc9	UTSW	6	142,584,959 (GRCm39)	missense	probably damaging	1.00
R4063:Abcc9	UTSW	6	142,551,645 (GRCm39)	missense	possibly damaging	0.94
R4065:Abcc9	UTSW	6	142,591,616 (GRCm39)	missense	probably damaging	1.00
R4290:Abcc9	UTSW	6	142,539,738 (GRCm39)	missense	probably benign	0.08
R4538:Abcc9	UTSW	6	142,560,138 (GRCm39)	critical splice donor site	probably null
R4615:Abcc9	UTSW	6	142,634,833 (GRCm39)	missense	possibly damaging	0.93
R4659:Abcc9	UTSW	6	142,618,321 (GRCm39)	splice site	probably null
R4774:Abcc9	UTSW	6	142,585,043 (GRCm39)	missense	probably damaging	1.00
R4832:Abcc9	UTSW	6	142,617,282 (GRCm39)	missense	probably damaging	1.00
R4844:Abcc9	UTSW	6	142,634,824 (GRCm39)	missense	probably benign	0.09
R4903:Abcc9	UTSW	6	142,546,691 (GRCm39)	missense	probably damaging	1.00
R4921:Abcc9	UTSW	6	142,536,162 (GRCm39)	missense	probably benign
R4960:Abcc9	UTSW	6	142,566,509 (GRCm39)	splice site	probably null
R4983:Abcc9	UTSW	6	142,627,867 (GRCm39)	missense	probably benign	0.44
R4986:Abcc9	UTSW	6	142,573,317 (GRCm39)	missense	probably benign	0.00
R5060:Abcc9	UTSW	6	142,571,836 (GRCm39)	intron	probably benign
R5120:Abcc9	UTSW	6	142,602,344 (GRCm39)	missense	probably benign	0.00
R5198:Abcc9	UTSW	6	142,571,726 (GRCm39)	missense	probably benign	0.00
R5301:Abcc9	UTSW	6	142,536,207 (GRCm39)	missense	probably benign	0.41
R5328:Abcc9	UTSW	6	142,627,785 (GRCm39)	missense	probably benign	0.25
R5568:Abcc9	UTSW	6	142,634,742 (GRCm39)	missense	possibly damaging	0.62
R5654:Abcc9	UTSW	6	142,571,371 (GRCm39)	intron	probably benign
R5694:Abcc9	UTSW	6	142,546,673 (GRCm39)	missense	probably damaging	1.00
R5734:Abcc9	UTSW	6	142,571,457 (GRCm39)	intron	probably benign
R5774:Abcc9	UTSW	6	142,574,285 (GRCm39)	missense	probably damaging	0.98
R5802:Abcc9	UTSW	6	142,602,402 (GRCm39)	critical splice acceptor site	probably null
R5890:Abcc9	UTSW	6	142,550,554 (GRCm39)	critical splice donor site	probably null
R5946:Abcc9	UTSW	6	142,571,678 (GRCm39)	missense	probably damaging	1.00
R5971:Abcc9	UTSW	6	142,585,301 (GRCm39)	missense	probably damaging	1.00
R6078:Abcc9	UTSW	6	142,585,301 (GRCm39)	missense	probably damaging	1.00
R6392:Abcc9	UTSW	6	142,627,825 (GRCm39)	missense	probably damaging	1.00
R6400:Abcc9	UTSW	6	142,638,435 (GRCm39)	makesense	probably null
R6478:Abcc9	UTSW	6	142,625,034 (GRCm39)	missense	probably damaging	1.00
R6481:Abcc9	UTSW	6	142,550,621 (GRCm39)	missense	probably damaging	0.99
R6564:Abcc9	UTSW	6	142,548,834 (GRCm39)	missense	probably damaging	1.00
R6700:Abcc9	UTSW	6	142,633,013 (GRCm39)	missense	possibly damaging	0.94
R6902:Abcc9	UTSW	6	142,624,953 (GRCm39)	missense	probably damaging	1.00
R6946:Abcc9	UTSW	6	142,624,953 (GRCm39)	missense	probably damaging	1.00
R6989:Abcc9	UTSW	6	142,634,707 (GRCm39)	missense	probably damaging	0.97
R7052:Abcc9	UTSW	6	142,604,261 (GRCm39)	missense	probably benign	0.00
R7062:Abcc9	UTSW	6	142,544,872 (GRCm39)	missense	probably damaging	1.00
R7121:Abcc9	UTSW	6	142,634,853 (GRCm39)	nonsense	probably null
R7284:Abcc9	UTSW	6	142,628,643 (GRCm39)	missense	probably damaging	1.00
R7296:Abcc9	UTSW	6	142,617,319 (GRCm39)	missense	probably damaging	1.00
R7353:Abcc9	UTSW	6	142,546,731 (GRCm39)	missense	probably damaging	1.00
R7359:Abcc9	UTSW	6	142,617,408 (GRCm39)	missense	probably damaging	1.00
R7815:Abcc9	UTSW	6	142,598,331 (GRCm39)	missense	probably damaging	1.00
R7894:Abcc9	UTSW	6	142,539,733 (GRCm39)	makesense	probably null
R8095:Abcc9	UTSW	6	142,590,048 (GRCm39)	missense	probably benign	0.22
R8099:Abcc9	UTSW	6	142,621,257 (GRCm39)	missense	probably damaging	1.00
R8245:Abcc9	UTSW	6	142,539,870 (GRCm39)	critical splice acceptor site	probably null
R8355:Abcc9	UTSW	6	142,638,478 (GRCm39)	missense	probably benign	0.00
R8356:Abcc9	UTSW	6	142,536,096 (GRCm39)	missense	probably benign	0.06
R8365:Abcc9	UTSW	6	142,544,798 (GRCm39)	missense	probably benign	0.03
R8846:Abcc9	UTSW	6	142,551,610 (GRCm39)	missense	possibly damaging	0.56
R8886:Abcc9	UTSW	6	142,546,420 (GRCm39)	intron	probably benign
R8939:Abcc9	UTSW	6	142,624,977 (GRCm39)	missense	probably damaging	0.99
R9049:Abcc9	UTSW	6	142,628,658 (GRCm39)	missense	probably damaging	0.99
R9113:Abcc9	UTSW	6	142,591,656 (GRCm39)	missense	probably damaging	1.00
R9368:Abcc9	UTSW	6	142,640,251 (GRCm39)	missense	probably damaging	1.00
R9401:Abcc9	UTSW	6	142,543,836 (GRCm39)	missense	possibly damaging	0.90
R9407:Abcc9	UTSW	6	142,574,229 (GRCm39)	missense	possibly damaging	0.88
R9597:Abcc9	UTSW	6	142,578,813 (GRCm39)	missense	possibly damaging	0.81
R9600:Abcc9	UTSW	6	142,536,102 (GRCm39)	missense	possibly damaging	0.54
R9687:Abcc9	UTSW	6	142,578,889 (GRCm39)	missense	probably benign	0.00
R9698:Abcc9	UTSW	6	142,571,757 (GRCm39)	missense	probably benign
R9761:Abcc9	UTSW	6	142,544,854 (GRCm39)	missense	possibly damaging	0.78
U15987:Abcc9	UTSW	6	142,585,301 (GRCm39)	missense	probably damaging	1.00
Z1177:Abcc9	UTSW	6	142,591,664 (GRCm39)	missense	probably null	0.96
Z1177:Abcc9	UTSW	6	142,571,708 (GRCm39)	missense	probably benign	0.07
Z1177:Abcc9	UTSW	6	142,540,484 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- CACTGGGTCAATTCCTTCTGT -3'
(R):5'- GGTTTTAAGAATGAGGACTTATGGGA -3'

Sequencing Primer
(F):5'- CAGATGAACCCTAATCAATGATGTTC -3'
(R):5'- CTTATGGGAAATAAATAAGAGGCGG -3'

Posted On

2015-12-29