Incidental Mutation 'R4792:Plxnb1'
| ID |
368690 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Plxnb1
|
| Ensembl Gene |
ENSMUSG00000053646 |
| Gene Name |
plexin B1 |
| Synonyms |
2900002G15Rik |
| MMRRC Submission |
042419-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4792 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
9 |
| Chromosomal Location |
108924457-108948985 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 108939716 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Asparagine
at position 1462
(D1462N)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000071966
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000072093]
|
| AlphaFold |
Q8CJH3 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000072093
AA Change: D1462N
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000071966
Gene: ENSMUSG00000053646
AA Change: D1462N
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
Sema
|
35 |
463 |
5.84e-101 |
SMART |
|
PSI
|
481 |
534 |
1.17e-13 |
SMART |
|
PSI
|
628 |
678 |
6.97e-3 |
SMART |
|
low complexity region
|
691 |
706 |
N/A |
INTRINSIC |
|
low complexity region
|
752 |
771 |
N/A |
INTRINSIC |
|
PSI
|
1019 |
1066 |
2.06e-5 |
SMART |
|
IPT
|
1067 |
1158 |
7.48e-18 |
SMART |
|
IPT
|
1159 |
1247 |
3.97e-22 |
SMART |
|
IPT
|
1249 |
1359 |
6.09e-9 |
SMART |
|
low complexity region
|
1483 |
1494 |
N/A |
INTRINSIC |
|
Pfam:Plexin_cytopl
|
1546 |
2086 |
6.5e-230 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000192117
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000192988
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000194734
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000195364
|
| Meta Mutation Damage Score |
0.1853 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.6%
- 20x: 93.3%
|
| Validation Efficiency |
97% (89/92) |
| MGI Phenotype |
PHENOTYPE: Homozygous null mutants are viable and fertile and show no apparent defects in development, adult histology or basic functional parameters. However, a transitory renal phenotype, characterized by increased ureteric branching and enlarged kidneys, is noted over early stages of renal development. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 82 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2310061N02Rik |
A |
G |
16: 88,504,651 (GRCm39) |
S49P |
possibly damaging |
Het |
| Abcb1a |
T |
C |
5: 8,796,657 (GRCm39) |
|
probably null |
Het |
| Adgb |
G |
A |
10: 10,274,647 (GRCm39) |
T770I |
probably damaging |
Het |
| Adgre4 |
A |
T |
17: 56,098,491 (GRCm39) |
T134S |
probably benign |
Het |
| Aldh1a1 |
A |
G |
19: 20,597,349 (GRCm39) |
N110S |
probably damaging |
Het |
| Alox5 |
C |
A |
6: 116,437,964 (GRCm39) |
V8L |
possibly damaging |
Het |
| Ambra1 |
A |
G |
2: 91,603,191 (GRCm39) |
T392A |
possibly damaging |
Het |
| Apob |
A |
G |
12: 8,058,051 (GRCm39) |
I2145V |
probably benign |
Het |
| Arhgap39 |
A |
G |
15: 76,625,717 (GRCm39) |
Y196H |
possibly damaging |
Het |
| Armh2 |
A |
G |
13: 24,930,490 (GRCm39) |
|
probably benign |
Het |
| Carmil1 |
A |
G |
13: 24,251,173 (GRCm39) |
L439S |
probably damaging |
Het |
| Carmil1 |
A |
T |
13: 24,325,659 (GRCm39) |
S224T |
possibly damaging |
Het |
| Cfh |
G |
A |
1: 140,028,561 (GRCm39) |
Q706* |
probably null |
Het |
| Chd2 |
A |
C |
7: 73,118,325 (GRCm39) |
S1098A |
probably benign |
Het |
| Chrna5 |
A |
T |
9: 54,911,985 (GRCm39) |
I158F |
probably damaging |
Het |
| Cilk1 |
A |
G |
9: 78,060,975 (GRCm39) |
D207G |
probably damaging |
Het |
| Col6a5 |
T |
C |
9: 105,807,983 (GRCm39) |
T1022A |
unknown |
Het |
| Cul7 |
T |
A |
17: 46,967,976 (GRCm39) |
Y423* |
probably null |
Het |
| Cyp2e1 |
T |
C |
7: 140,353,588 (GRCm39) |
Y342H |
probably benign |
Het |
| D630045J12Rik |
T |
C |
6: 38,125,275 (GRCm39) |
K1580E |
probably damaging |
Het |
| Dnah6 |
A |
G |
6: 73,066,651 (GRCm39) |
M2573T |
probably damaging |
Het |
| Dnai4 |
T |
C |
4: 102,929,881 (GRCm39) |
K370R |
possibly damaging |
Het |
| Edem1 |
T |
A |
6: 108,805,707 (GRCm39) |
|
probably benign |
Het |
| Erp29 |
C |
T |
5: 121,585,237 (GRCm39) |
E86K |
probably benign |
Het |
| Esrp2 |
C |
A |
8: 106,859,141 (GRCm39) |
R535L |
probably damaging |
Het |
| Gabrb2 |
C |
T |
11: 42,420,330 (GRCm39) |
|
probably benign |
Het |
| Gpat3 |
C |
T |
5: 101,005,039 (GRCm39) |
P58L |
probably benign |
Het |
| Herc1 |
T |
A |
9: 66,403,266 (GRCm39) |
V4395E |
possibly damaging |
Het |
| Hivep2 |
C |
A |
10: 14,004,713 (GRCm39) |
T437K |
probably benign |
Het |
| Hmgb2 |
G |
A |
8: 57,966,344 (GRCm39) |
C106Y |
probably damaging |
Het |
| Hoxa10 |
T |
C |
6: 52,209,481 (GRCm39) |
|
probably benign |
Het |
| Hsd3b1 |
T |
A |
3: 98,760,226 (GRCm39) |
Y255F |
probably benign |
Het |
| Ighd |
T |
C |
12: 113,379,819 (GRCm39) |
K42E |
probably benign |
Het |
| Ighv1-26 |
T |
C |
12: 114,752,191 (GRCm39) |
Y51C |
possibly damaging |
Het |
| Ighv5-2 |
C |
T |
12: 113,542,419 (GRCm39) |
E19K |
possibly damaging |
Het |
| Ipo11 |
T |
C |
13: 106,970,668 (GRCm39) |
|
probably benign |
Het |
| Itk |
C |
T |
11: 46,235,658 (GRCm39) |
|
probably benign |
Het |
| Kat6a |
T |
A |
8: 23,430,592 (GRCm39) |
H1982Q |
unknown |
Het |
| Kdm4d |
C |
T |
9: 14,374,686 (GRCm39) |
V391I |
probably benign |
Het |
| Klk14 |
G |
A |
7: 43,341,501 (GRCm39) |
C51Y |
probably damaging |
Het |
| Lgr6 |
T |
A |
1: 134,949,544 (GRCm39) |
S229C |
probably benign |
Het |
| Lhx9 |
T |
A |
1: 138,766,089 (GRCm39) |
Y233F |
possibly damaging |
Het |
| Lmf1 |
G |
A |
17: 25,873,445 (GRCm39) |
V317M |
probably damaging |
Het |
| Mapk4 |
T |
C |
18: 74,070,321 (GRCm39) |
T191A |
probably damaging |
Het |
| Mrc2 |
G |
A |
11: 105,239,257 (GRCm39) |
|
probably null |
Het |
| Naglu |
C |
T |
11: 100,961,932 (GRCm39) |
T135M |
probably damaging |
Het |
| Nomo1 |
T |
A |
7: 45,693,643 (GRCm39) |
|
probably null |
Het |
| Nop56 |
T |
A |
2: 130,119,784 (GRCm39) |
V75E |
possibly damaging |
Het |
| Nr1i3 |
G |
A |
1: 171,046,164 (GRCm39) |
C283Y |
probably damaging |
Het |
| Or4x6 |
T |
A |
2: 89,949,174 (GRCm39) |
Y256F |
possibly damaging |
Het |
| Or51d1 |
G |
A |
7: 102,347,933 (GRCm39) |
G163R |
probably damaging |
Het |
| Or6c38 |
T |
G |
10: 128,929,489 (GRCm39) |
Y118S |
probably damaging |
Het |
| Pcdhga2 |
A |
G |
18: 37,802,452 (GRCm39) |
S99G |
probably benign |
Het |
| Pcnx1 |
T |
A |
12: 81,965,925 (GRCm39) |
D697E |
probably damaging |
Het |
| Pnn |
G |
T |
12: 59,118,991 (GRCm39) |
V525F |
possibly damaging |
Het |
| Prrc2a |
A |
T |
17: 35,375,463 (GRCm39) |
D1062E |
probably damaging |
Het |
| Prss35 |
T |
A |
9: 86,637,722 (GRCm39) |
V164E |
probably damaging |
Het |
| Psapl1 |
T |
C |
5: 36,362,547 (GRCm39) |
S380P |
probably benign |
Het |
| Rnf222 |
A |
T |
11: 68,783,845 (GRCm39) |
E137D |
probably damaging |
Het |
| Rsph10b |
A |
G |
5: 143,874,135 (GRCm39) |
T79A |
probably damaging |
Het |
| Sbf2 |
T |
C |
7: 109,950,817 (GRCm39) |
Q1164R |
probably damaging |
Het |
| Scn7a |
T |
C |
2: 66,556,592 (GRCm39) |
D331G |
probably damaging |
Het |
| Shtn1 |
G |
C |
19: 59,039,305 (GRCm39) |
R45G |
probably damaging |
Het |
| Sspo |
G |
A |
6: 48,438,519 (GRCm39) |
S1529N |
probably benign |
Het |
| St8sia3 |
T |
A |
18: 64,398,634 (GRCm39) |
V31E |
probably benign |
Het |
| Sult1b1 |
A |
T |
5: 87,662,906 (GRCm39) |
W265R |
probably damaging |
Het |
| Supt5 |
G |
T |
7: 28,015,754 (GRCm39) |
Q863K |
probably benign |
Het |
| Tbc1d31 |
A |
G |
15: 57,804,124 (GRCm39) |
R380G |
probably benign |
Het |
| Tdpoz1 |
T |
A |
3: 93,577,845 (GRCm39) |
D313V |
possibly damaging |
Het |
| Tmem260 |
CAGGGACCGGCATAG |
CAG |
14: 48,749,451 (GRCm39) |
|
probably benign |
Het |
| Tpx2 |
A |
T |
2: 152,727,016 (GRCm39) |
T428S |
probably damaging |
Het |
| Trip11 |
A |
T |
12: 101,851,705 (GRCm39) |
H786Q |
probably benign |
Het |
| Trpc6 |
A |
T |
9: 8,626,615 (GRCm39) |
M322L |
probably benign |
Het |
| Try10 |
T |
C |
6: 41,332,386 (GRCm39) |
V14A |
probably benign |
Het |
| Unc13d |
A |
T |
11: 115,961,108 (GRCm39) |
F416L |
probably damaging |
Het |
| Vmn2r75 |
A |
T |
7: 85,812,378 (GRCm39) |
M547K |
possibly damaging |
Het |
| Zbp1 |
A |
G |
2: 173,051,006 (GRCm39) |
F288S |
probably damaging |
Het |
| Zc3h11a |
T |
A |
1: 133,568,436 (GRCm39) |
Q71L |
probably damaging |
Het |
| Zfp40 |
G |
A |
17: 23,396,008 (GRCm39) |
T193I |
possibly damaging |
Het |
| Zfp607a |
T |
C |
7: 27,578,078 (GRCm39) |
Y383H |
probably benign |
Het |
| Zfp622 |
T |
A |
15: 25,987,128 (GRCm39) |
Y82* |
probably null |
Het |
| Zfp964 |
T |
C |
8: 70,116,665 (GRCm39) |
F422L |
probably benign |
Het |
|
| Other mutations in Plxnb1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00593:Plxnb1
|
APN |
9 |
108,942,936 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL01014:Plxnb1
|
APN |
9 |
108,935,102 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01142:Plxnb1
|
APN |
9 |
108,931,765 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL01454:Plxnb1
|
APN |
9 |
108,942,422 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01469:Plxnb1
|
APN |
9 |
108,934,483 (GRCm39) |
intron |
probably benign |
|
|
IGL01530:Plxnb1
|
APN |
9 |
108,939,473 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01599:Plxnb1
|
APN |
9 |
108,939,672 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01968:Plxnb1
|
APN |
9 |
108,930,052 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02175:Plxnb1
|
APN |
9 |
108,929,914 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
IGL02216:Plxnb1
|
APN |
9 |
108,929,918 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02277:Plxnb1
|
APN |
9 |
108,941,201 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02311:Plxnb1
|
APN |
9 |
108,930,190 (GRCm39) |
missense |
probably benign |
|
|
IGL02645:Plxnb1
|
APN |
9 |
108,943,311 (GRCm39) |
splice site |
probably benign |
|
|
IGL03076:Plxnb1
|
APN |
9 |
108,935,970 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL03107:Plxnb1
|
APN |
9 |
108,934,054 (GRCm39) |
missense |
probably benign |
|
|
IGL03343:Plxnb1
|
APN |
9 |
108,943,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4431001:Plxnb1
|
UTSW |
9 |
108,929,786 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0117:Plxnb1
|
UTSW |
9 |
108,934,286 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0211:Plxnb1
|
UTSW |
9 |
108,932,731 (GRCm39) |
nonsense |
probably null |
|
|
R0211:Plxnb1
|
UTSW |
9 |
108,932,731 (GRCm39) |
nonsense |
probably null |
|
|
R0843:Plxnb1
|
UTSW |
9 |
108,942,769 (GRCm39) |
missense |
probably benign |
0.20 |
|
R0970:Plxnb1
|
UTSW |
9 |
108,932,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0973:Plxnb1
|
UTSW |
9 |
108,931,210 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R1342:Plxnb1
|
UTSW |
9 |
108,929,720 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R1386:Plxnb1
|
UTSW |
9 |
108,930,091 (GRCm39) |
missense |
probably benign |
0.27 |
|
R1419:Plxnb1
|
UTSW |
9 |
108,943,454 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1445:Plxnb1
|
UTSW |
9 |
108,937,989 (GRCm39) |
missense |
probably null |
|
|
R1548:Plxnb1
|
UTSW |
9 |
108,929,968 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1621:Plxnb1
|
UTSW |
9 |
108,935,873 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1658:Plxnb1
|
UTSW |
9 |
108,931,939 (GRCm39) |
nonsense |
probably null |
|
|
R1727:Plxnb1
|
UTSW |
9 |
108,930,125 (GRCm39) |
splice site |
probably null |
|
|
R1750:Plxnb1
|
UTSW |
9 |
108,940,836 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1795:Plxnb1
|
UTSW |
9 |
108,929,813 (GRCm39) |
missense |
probably benign |
|
|
R1929:Plxnb1
|
UTSW |
9 |
108,931,776 (GRCm39) |
splice site |
probably null |
|
|
R1935:Plxnb1
|
UTSW |
9 |
108,924,715 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1936:Plxnb1
|
UTSW |
9 |
108,924,715 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2014:Plxnb1
|
UTSW |
9 |
108,935,687 (GRCm39) |
splice site |
probably benign |
|
|
R2057:Plxnb1
|
UTSW |
9 |
108,938,294 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R2102:Plxnb1
|
UTSW |
9 |
108,944,810 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2271:Plxnb1
|
UTSW |
9 |
108,931,776 (GRCm39) |
splice site |
probably null |
|
|
R2422:Plxnb1
|
UTSW |
9 |
108,937,506 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2881:Plxnb1
|
UTSW |
9 |
108,943,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3409:Plxnb1
|
UTSW |
9 |
108,935,681 (GRCm39) |
splice site |
probably null |
|
|
R3417:Plxnb1
|
UTSW |
9 |
108,929,828 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3756:Plxnb1
|
UTSW |
9 |
108,942,526 (GRCm39) |
unclassified |
probably benign |
|
|
R3788:Plxnb1
|
UTSW |
9 |
108,938,355 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R3789:Plxnb1
|
UTSW |
9 |
108,938,355 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R4042:Plxnb1
|
UTSW |
9 |
108,934,241 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4289:Plxnb1
|
UTSW |
9 |
108,943,420 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4396:Plxnb1
|
UTSW |
9 |
108,929,291 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R4564:Plxnb1
|
UTSW |
9 |
108,942,488 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4676:Plxnb1
|
UTSW |
9 |
108,939,503 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R4706:Plxnb1
|
UTSW |
9 |
108,941,096 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4796:Plxnb1
|
UTSW |
9 |
108,943,663 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4835:Plxnb1
|
UTSW |
9 |
108,934,442 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4901:Plxnb1
|
UTSW |
9 |
108,934,027 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4952:Plxnb1
|
UTSW |
9 |
108,943,904 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5005:Plxnb1
|
UTSW |
9 |
108,935,647 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5015:Plxnb1
|
UTSW |
9 |
108,929,498 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5029:Plxnb1
|
UTSW |
9 |
108,943,723 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5180:Plxnb1
|
UTSW |
9 |
108,940,761 (GRCm39) |
splice site |
probably null |
|
|
R5256:Plxnb1
|
UTSW |
9 |
108,943,661 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5285:Plxnb1
|
UTSW |
9 |
108,937,527 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5431:Plxnb1
|
UTSW |
9 |
108,929,840 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5444:Plxnb1
|
UTSW |
9 |
108,935,521 (GRCm39) |
missense |
probably benign |
0.22 |
|
R5546:Plxnb1
|
UTSW |
9 |
108,929,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5852:Plxnb1
|
UTSW |
9 |
108,935,518 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5892:Plxnb1
|
UTSW |
9 |
108,940,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6020:Plxnb1
|
UTSW |
9 |
108,945,679 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6053:Plxnb1
|
UTSW |
9 |
108,940,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6177:Plxnb1
|
UTSW |
9 |
108,931,993 (GRCm39) |
splice site |
probably null |
|
|
R6193:Plxnb1
|
UTSW |
9 |
108,933,971 (GRCm39) |
missense |
probably benign |
|
|
R6274:Plxnb1
|
UTSW |
9 |
108,941,209 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6310:Plxnb1
|
UTSW |
9 |
108,938,796 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6404:Plxnb1
|
UTSW |
9 |
108,945,705 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6422:Plxnb1
|
UTSW |
9 |
108,937,992 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6479:Plxnb1
|
UTSW |
9 |
108,940,733 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R6555:Plxnb1
|
UTSW |
9 |
108,937,473 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6646:Plxnb1
|
UTSW |
9 |
108,937,895 (GRCm39) |
missense |
probably benign |
|
|
R6648:Plxnb1
|
UTSW |
9 |
108,933,398 (GRCm39) |
missense |
probably benign |
0.14 |
|
R6661:Plxnb1
|
UTSW |
9 |
108,933,367 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6674:Plxnb1
|
UTSW |
9 |
108,937,214 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6734:Plxnb1
|
UTSW |
9 |
108,937,988 (GRCm39) |
nonsense |
probably null |
|
|
R6859:Plxnb1
|
UTSW |
9 |
108,935,838 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6948:Plxnb1
|
UTSW |
9 |
108,945,702 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7030:Plxnb1
|
UTSW |
9 |
108,941,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7038:Plxnb1
|
UTSW |
9 |
108,929,453 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7204:Plxnb1
|
UTSW |
9 |
108,929,243 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7427:Plxnb1
|
UTSW |
9 |
108,937,236 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7428:Plxnb1
|
UTSW |
9 |
108,937,236 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7443:Plxnb1
|
UTSW |
9 |
108,943,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7527:Plxnb1
|
UTSW |
9 |
108,929,929 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7645:Plxnb1
|
UTSW |
9 |
108,943,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7680:Plxnb1
|
UTSW |
9 |
108,929,571 (GRCm39) |
nonsense |
probably null |
|
|
R7866:Plxnb1
|
UTSW |
9 |
108,929,525 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7898:Plxnb1
|
UTSW |
9 |
108,943,408 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7905:Plxnb1
|
UTSW |
9 |
108,938,300 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8092:Plxnb1
|
UTSW |
9 |
108,929,573 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8150:Plxnb1
|
UTSW |
9 |
108,941,146 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8286:Plxnb1
|
UTSW |
9 |
108,935,870 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8290:Plxnb1
|
UTSW |
9 |
108,938,687 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8987:Plxnb1
|
UTSW |
9 |
108,937,178 (GRCm39) |
splice site |
probably benign |
|
|
R9176:Plxnb1
|
UTSW |
9 |
108,941,651 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9231:Plxnb1
|
UTSW |
9 |
108,934,286 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R9698:Plxnb1
|
UTSW |
9 |
108,925,251 (GRCm39) |
start gained |
probably benign |
|
|
Z1177:Plxnb1
|
UTSW |
9 |
108,937,989 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
| Predicted Primers |
PCR Primer
(F):5'- AACCACCTGTACTGTGAGCC -3'
(R):5'- TGCAACCATTTCCAGAGGAC -3'
Sequencing Primer
(F):5'- TGTACTGTGAGCCCCCTGTG -3'
(R):5'- TATGTATGTACACACGCGCG -3'
|
| Posted On |
2016-02-04 |
Incidental Mutation