Incidental Mutation 'R4113:Gm5611'
ID314504
Institutional Source Beutler Lab
Gene Symbol Gm5611
Ensembl Gene ENSMUSG00000090602
Gene Namepredicted gene 5611
Synonyms
Accession Numbers
Is this an essential gene? Probably essential (E-score: 0.964) question?
Stock #R4113 (G1)
Quality Score225
Status Not validated
Chromosome9
Chromosomal Location17030045-17030899 bp(+) (GRCm38)
Type of Mutationexon
DNA Base Change (assembly) T to A at 17030693 bp
ZygosityHeterozygous
Amino Acid Change
Gene Model predicted gene model for transcript(s):
Predicted Effect noncoding transcript
Transcript: ENSMUST00000164523
SMART Domains Protein: ENSMUSP00000130546
Gene: ENSMUSG00000090602

DomainStartEndE-ValueType
Pfam:Nucleoplasmin 12 173 7.7e-64 PFAM
low complexity region 207 219 N/A INTRINSIC
Pfam:NPM1-C 223 271 8.1e-38 PFAM
Coding Region Coverage
  • 1x: 99.2%
  • 3x: 98.6%
  • 10x: 97.6%
  • 20x: 96.1%
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 40 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Bace2 A G 16: 97,436,656 T436A probably benign Het
BC024139 A G 15: 76,121,627 M458T probably benign Het
Casp2 G A 6: 42,267,894 A76T probably damaging Het
Catsper3 A G 13: 55,786,370 K35E probably damaging Het
Ccdc88c A G 12: 100,945,073 L34P probably damaging Het
Dcaf13 T A 15: 39,130,220 I236N probably damaging Het
Dip2c G T 13: 9,637,101 G1254C probably damaging Het
Dnah12 T C 14: 26,693,567 L41P probably damaging Het
Dnah17 T C 11: 118,112,594 K514R possibly damaging Het
Dnajb12 T A 10: 59,894,314 S270R possibly damaging Het
Dnajc28 G A 16: 91,616,867 T187M probably damaging Het
Eya4 G T 10: 23,155,951 S235Y probably damaging Het
Fam208a C T 14: 27,459,961 R483* probably null Het
Fat3 G A 9: 15,998,271 S2145F probably damaging Het
Gdf3 A G 6: 122,607,057 I117T probably damaging Het
Gtf3c4 G A 2: 28,827,555 T771I probably damaging Het
Hrh3 C A 2: 180,102,850 R99L possibly damaging Het
Hyls1 T A 9: 35,561,418 Y234F probably damaging Het
Irak1bp1 T C 9: 82,846,675 S220P probably benign Het
Lama1 G A 17: 67,764,703 V862I probably benign Het
Mrc2 G A 11: 105,348,431 probably null Het
Olfr1271 A T 2: 90,266,340 L30H probably damaging Het
Olfr304 G A 7: 86,386,525 T45M possibly damaging Het
Pcdh8 T C 14: 79,767,513 D927G probably damaging Het
Prelid3a T C 18: 67,472,897 Y25H probably damaging Het
Ptprm T C 17: 66,725,813 D1015G probably damaging Het
Rhox3f G T X: 37,582,019 E140* probably null Het
Riox2 C T 16: 59,491,894 L465F probably benign Het
Sec31b G T 19: 44,524,529 T507N possibly damaging Het
Stab1 C T 14: 31,168,479 R5Q probably damaging Het
Stmn3 T C 2: 181,307,296 K135E possibly damaging Het
Synj2 G A 17: 6,007,965 G243S probably benign Het
Tns2 C T 15: 102,108,934 R281C probably damaging Het
Tshz2 C A 2: 169,885,530 P213Q probably benign Het
Tssk4 A G 14: 55,650,373 T9A probably benign Het
Ube4a T A 9: 44,948,949 I272F probably damaging Het
Unc79 T C 12: 103,059,370 C339R probably damaging Het
Vmn2r87 T C 10: 130,479,822 D125G probably benign Het
Yap1 A T 9: 7,938,431 *358K probably null Het
Zfp992 C T 4: 146,467,519 H566Y probably damaging Het
Other mutations in Gm5611
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01615:Gm5611 APN 9 17030351 exon noncoding transcript
IGL01763:Gm5611 APN 9 17030403 exon noncoding transcript
IGL01800:Gm5611 APN 9 17030471 exon noncoding transcript
R1536:Gm5611 UTSW 9 17030607 exon noncoding transcript
R1830:Gm5611 UTSW 9 17030777 exon noncoding transcript
R4111:Gm5611 UTSW 9 17030693 exon noncoding transcript
Predicted Primers PCR Primer
(F):5'- ATGTCTGGGAAGCGATCTGC -3'
(R):5'- ATAGCCTCCTGGTCAGTCATC -3'

Sequencing Primer
(F):5'- ATCTGCTCCTGGAGGTGGTAAC -3'
(R):5'- TGGTCAGTCATCCGGAAAC -3'
Posted On2015-05-14