Incidental Mutation 'R4067:Dync2i2'
| ID |
316146 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dync2i2
|
| Ensembl Gene |
ENSMUSG00000039715 |
| Gene Name |
dynein 2 intermediate chain 2 |
| Synonyms |
3200002I06Rik, Wdr34 |
| MMRRC Submission |
040853-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.544)
|
| Stock # |
R4067 (G1)
|
| Quality Score |
203 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
29921563-29938891 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 29922820 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Proline
at position 309
(L309P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000109340
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000046257]
[ENSMUST00000095083]
[ENSMUST00000100225]
[ENSMUST00000113711]
[ENSMUST00000113717]
[ENSMUST00000113719]
[ENSMUST00000129241]
|
| AlphaFold |
Q5U4F6 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000046257
|
| SMART Domains |
Protein: ENSMUSP00000047792
Gene: ENSMUSG00000057738
| Domain | Start | End | E-Value | Type |
|---|
|
SPEC
|
47 |
146 |
2.1e-30 |
SMART |
|
SPEC
|
152 |
252 |
2.6e-35 |
SMART |
|
SPEC
|
258 |
358 |
4.93e-36 |
SMART |
|
SPEC
|
364 |
464 |
1.08e-27 |
SMART |
|
SPEC
|
470 |
570 |
9.01e-30 |
SMART |
|
SPEC
|
576 |
675 |
3.52e-32 |
SMART |
|
SPEC
|
681 |
781 |
2.15e-36 |
SMART |
|
SPEC
|
787 |
887 |
2.45e-40 |
SMART |
|
SPEC
|
893 |
1068 |
1.18e-24 |
SMART |
|
SH3
|
970 |
1025 |
8.24e-18 |
SMART |
|
SPEC
|
1074 |
1210 |
6.52e-27 |
SMART |
|
SPEC
|
1216 |
1316 |
1.44e-37 |
SMART |
|
SPEC
|
1322 |
1422 |
4.43e-29 |
SMART |
|
SPEC
|
1428 |
1528 |
7.54e-32 |
SMART |
|
SPEC
|
1534 |
1635 |
9.65e-30 |
SMART |
|
SPEC
|
1641 |
1741 |
2.32e-32 |
SMART |
|
SPEC
|
1747 |
1847 |
6.98e-36 |
SMART |
|
SPEC
|
1853 |
1953 |
1.53e-32 |
SMART |
|
SPEC
|
1959 |
2060 |
6.23e-24 |
SMART |
|
SPEC
|
2074 |
2174 |
2.08e-11 |
SMART |
|
SPEC
|
2188 |
2289 |
1.07e-4 |
SMART |
|
EFh
|
2307 |
2335 |
5.78e-7 |
SMART |
|
EFh
|
2350 |
2378 |
3.85e-3 |
SMART |
|
efhand_Ca_insen
|
2382 |
2451 |
6.74e-32 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000095083
|
| SMART Domains |
Protein: ENSMUSP00000092697
Gene: ENSMUSG00000057738
| Domain | Start | End | E-Value | Type |
|---|
|
SPEC
|
47 |
146 |
2.1e-30 |
SMART |
|
SPEC
|
152 |
252 |
2.6e-35 |
SMART |
|
SPEC
|
258 |
358 |
4.93e-36 |
SMART |
|
SPEC
|
364 |
464 |
1.08e-27 |
SMART |
|
SPEC
|
470 |
570 |
9.01e-30 |
SMART |
|
SPEC
|
576 |
675 |
3.52e-32 |
SMART |
|
SPEC
|
681 |
781 |
2.15e-36 |
SMART |
|
SPEC
|
787 |
887 |
2.45e-40 |
SMART |
|
SPEC
|
893 |
1088 |
1.56e-24 |
SMART |
|
SH3
|
970 |
1025 |
8.24e-18 |
SMART |
|
SPEC
|
1094 |
1230 |
6.52e-27 |
SMART |
|
SPEC
|
1236 |
1336 |
1.44e-37 |
SMART |
|
SPEC
|
1342 |
1442 |
4.43e-29 |
SMART |
|
SPEC
|
1448 |
1548 |
7.54e-32 |
SMART |
|
SPEC
|
1554 |
1655 |
9.65e-30 |
SMART |
|
SPEC
|
1661 |
1761 |
2.32e-32 |
SMART |
|
SPEC
|
1767 |
1867 |
6.98e-36 |
SMART |
|
SPEC
|
1873 |
1973 |
1.53e-32 |
SMART |
|
SPEC
|
1979 |
2080 |
6.23e-24 |
SMART |
|
SPEC
|
2094 |
2194 |
2.08e-11 |
SMART |
|
SPEC
|
2208 |
2309 |
1.07e-4 |
SMART |
|
EFh
|
2327 |
2355 |
5.78e-7 |
SMART |
|
EFh
|
2370 |
2398 |
3.85e-3 |
SMART |
|
efhand_Ca_insen
|
2402 |
2471 |
6.74e-32 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000100225
|
| SMART Domains |
Protein: ENSMUSP00000097797
Gene: ENSMUSG00000057738
| Domain | Start | End | E-Value | Type |
|---|
|
SPEC
|
47 |
146 |
2.1e-30 |
SMART |
|
SPEC
|
152 |
252 |
2.6e-35 |
SMART |
|
SPEC
|
258 |
358 |
4.93e-36 |
SMART |
|
SPEC
|
364 |
464 |
1.08e-27 |
SMART |
|
SPEC
|
470 |
570 |
9.01e-30 |
SMART |
|
SPEC
|
576 |
675 |
3.52e-32 |
SMART |
|
SPEC
|
681 |
781 |
2.15e-36 |
SMART |
|
SPEC
|
787 |
887 |
2.45e-40 |
SMART |
|
SPEC
|
893 |
1088 |
1.56e-24 |
SMART |
|
SH3
|
970 |
1025 |
8.24e-18 |
SMART |
|
SPEC
|
1094 |
1230 |
6.52e-27 |
SMART |
|
SPEC
|
1236 |
1336 |
1.44e-37 |
SMART |
|
SPEC
|
1342 |
1442 |
4.43e-29 |
SMART |
|
SPEC
|
1448 |
1548 |
7.54e-32 |
SMART |
|
SPEC
|
1554 |
1660 |
2.06e-24 |
SMART |
|
SPEC
|
1666 |
1766 |
2.32e-32 |
SMART |
|
SPEC
|
1772 |
1872 |
6.98e-36 |
SMART |
|
SPEC
|
1878 |
1978 |
1.53e-32 |
SMART |
|
SPEC
|
1984 |
2085 |
6.23e-24 |
SMART |
|
SPEC
|
2099 |
2199 |
2.08e-11 |
SMART |
|
SPEC
|
2213 |
2314 |
1.07e-4 |
SMART |
|
EFh
|
2332 |
2360 |
5.78e-7 |
SMART |
|
EFh
|
2375 |
2403 |
3.85e-3 |
SMART |
|
efhand_Ca_insen
|
2407 |
2476 |
6.74e-32 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113711
AA Change: L309P
PolyPhen 2
Score 0.028 (Sensitivity: 0.95; Specificity: 0.81)
|
| SMART Domains |
Protein: ENSMUSP00000109340
Gene: ENSMUSG00000039715
AA Change: L309P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
11 |
36 |
N/A |
INTRINSIC |
|
low complexity region
|
90 |
100 |
N/A |
INTRINSIC |
|
Blast:WD40
|
146 |
200 |
3e-28 |
BLAST |
|
WD40
|
207 |
247 |
2e-1 |
SMART |
|
WD40
|
256 |
300 |
3.42e1 |
SMART |
|
Blast:WD40
|
323 |
364 |
8e-10 |
BLAST |
|
WD40
|
382 |
422 |
1.66e-5 |
SMART |
|
WD40
|
425 |
465 |
3.09e-1 |
SMART |
|
WD40
|
470 |
512 |
4.18e-2 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113717
|
| SMART Domains |
Protein: ENSMUSP00000109346
Gene: ENSMUSG00000057738
| Domain | Start | End | E-Value | Type |
|---|
|
SPEC
|
47 |
146 |
2.1e-30 |
SMART |
|
SPEC
|
152 |
252 |
2.6e-35 |
SMART |
|
SPEC
|
258 |
358 |
4.93e-36 |
SMART |
|
SPEC
|
364 |
464 |
1.08e-27 |
SMART |
|
SPEC
|
470 |
570 |
9.01e-30 |
SMART |
|
SPEC
|
576 |
675 |
3.52e-32 |
SMART |
|
SPEC
|
681 |
781 |
2.15e-36 |
SMART |
|
SPEC
|
787 |
887 |
2.45e-40 |
SMART |
|
SPEC
|
893 |
1068 |
1.18e-24 |
SMART |
|
SH3
|
970 |
1025 |
8.24e-18 |
SMART |
|
SPEC
|
1074 |
1210 |
6.52e-27 |
SMART |
|
SPEC
|
1216 |
1316 |
1.44e-37 |
SMART |
|
SPEC
|
1322 |
1422 |
4.43e-29 |
SMART |
|
SPEC
|
1428 |
1528 |
7.54e-32 |
SMART |
|
SPEC
|
1534 |
1640 |
2.06e-24 |
SMART |
|
SPEC
|
1646 |
1746 |
2.32e-32 |
SMART |
|
SPEC
|
1752 |
1852 |
6.98e-36 |
SMART |
|
SPEC
|
1858 |
1958 |
1.53e-32 |
SMART |
|
SPEC
|
1964 |
2065 |
6.23e-24 |
SMART |
|
SPEC
|
2079 |
2179 |
2.08e-11 |
SMART |
|
SPEC
|
2193 |
2294 |
1.07e-4 |
SMART |
|
EFh
|
2312 |
2340 |
5.78e-7 |
SMART |
|
EFh
|
2355 |
2383 |
3.85e-3 |
SMART |
|
efhand_Ca_insen
|
2387 |
2456 |
6.74e-32 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113719
|
| SMART Domains |
Protein: ENSMUSP00000109348
Gene: ENSMUSG00000057738
| Domain | Start | End | E-Value | Type |
|---|
|
SPEC
|
47 |
146 |
2.1e-30 |
SMART |
|
SPEC
|
152 |
252 |
2.6e-35 |
SMART |
|
SPEC
|
258 |
358 |
4.93e-36 |
SMART |
|
SPEC
|
364 |
464 |
1.08e-27 |
SMART |
|
SPEC
|
470 |
570 |
9.01e-30 |
SMART |
|
SPEC
|
576 |
675 |
3.52e-32 |
SMART |
|
SPEC
|
681 |
781 |
2.15e-36 |
SMART |
|
SPEC
|
787 |
887 |
2.45e-40 |
SMART |
|
SPEC
|
893 |
1068 |
1.18e-24 |
SMART |
|
SH3
|
970 |
1025 |
8.24e-18 |
SMART |
|
SPEC
|
1074 |
1210 |
6.52e-27 |
SMART |
|
SPEC
|
1216 |
1316 |
1.44e-37 |
SMART |
|
SPEC
|
1322 |
1422 |
4.43e-29 |
SMART |
|
SPEC
|
1428 |
1528 |
7.54e-32 |
SMART |
|
SPEC
|
1534 |
1640 |
2.06e-24 |
SMART |
|
SPEC
|
1646 |
1746 |
2.32e-32 |
SMART |
|
SPEC
|
1752 |
1852 |
6.98e-36 |
SMART |
|
SPEC
|
1858 |
1958 |
1.53e-32 |
SMART |
|
SPEC
|
1964 |
2065 |
6.23e-24 |
SMART |
|
SPEC
|
2079 |
2179 |
2.08e-11 |
SMART |
|
SPEC
|
2193 |
2315 |
3.27e0 |
SMART |
|
EFh
|
2333 |
2361 |
5.78e-7 |
SMART |
|
EFh
|
2376 |
2404 |
3.85e-3 |
SMART |
|
efhand_Ca_insen
|
2408 |
2477 |
6.74e-32 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000124494
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000139145
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000143892
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000152453
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000201758
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000129241
|
| SMART Domains |
Protein: ENSMUSP00000121116
Gene: ENSMUSG00000057738
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Spectrin
|
1 |
65 |
9.9e-10 |
PFAM |
|
SPEC
|
78 |
178 |
2.08e-11 |
SMART |
|
SPEC
|
192 |
314 |
3.27e0 |
SMART |
|
EFh
|
332 |
360 |
5.78e-7 |
SMART |
|
EFh
|
375 |
403 |
3.85e-3 |
SMART |
|
efhand_Ca_insen
|
407 |
476 |
6.74e-32 |
SMART |
|
| Meta Mutation Damage Score |
0.5475 |
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.7%
- 10x: 97.4%
- 20x: 95.8%
|
| Validation Efficiency |
98% (61/62) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Defects in this gene are a cause of short-rib thoracic dysplasia 11 with or without polydactyly. [provided by RefSeq, Mar 2014]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 58 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700025G04Rik |
T |
A |
1: 151,769,150 (GRCm39) |
T121S |
possibly damaging |
Het |
| 4930503E14Rik |
T |
C |
14: 44,406,641 (GRCm39) |
E136G |
probably damaging |
Het |
| Adgrg4 |
A |
G |
X: 56,005,320 (GRCm39) |
N2527S |
probably damaging |
Het |
| Ak1 |
G |
A |
2: 32,519,593 (GRCm39) |
S7N |
probably benign |
Het |
| Aktip |
A |
C |
8: 91,852,466 (GRCm39) |
I230R |
possibly damaging |
Het |
| Alms1 |
A |
G |
6: 85,598,271 (GRCm39) |
I1032M |
probably damaging |
Het |
| Asb4 |
T |
A |
6: 5,423,651 (GRCm39) |
V266E |
probably damaging |
Het |
| Bace1 |
G |
A |
9: 45,765,962 (GRCm39) |
V130M |
probably damaging |
Het |
| Bglap |
A |
T |
3: 88,291,744 (GRCm39) |
|
probably benign |
Het |
| Brpf3 |
T |
C |
17: 29,040,233 (GRCm39) |
S885P |
probably benign |
Het |
| Chd9 |
A |
T |
8: 91,750,202 (GRCm39) |
I1742F |
possibly damaging |
Het |
| Col9a2 |
T |
A |
4: 120,909,586 (GRCm39) |
I415N |
probably damaging |
Het |
| Cybc1 |
A |
T |
11: 121,115,528 (GRCm39) |
|
probably null |
Het |
| Dnajc7 |
T |
C |
11: 100,492,607 (GRCm39) |
Y38C |
probably benign |
Het |
| Enam |
A |
G |
5: 88,651,236 (GRCm39) |
Y840C |
probably damaging |
Het |
| Etnppl |
T |
A |
3: 130,425,442 (GRCm39) |
C416S |
probably damaging |
Het |
| Fgf20 |
A |
T |
8: 40,732,896 (GRCm39) |
S181T |
probably benign |
Het |
| Fut8 |
T |
A |
12: 77,510,835 (GRCm39) |
Y421N |
probably damaging |
Het |
| Gcn1 |
T |
G |
5: 115,737,147 (GRCm39) |
L1295R |
probably damaging |
Het |
| Gm11437 |
A |
G |
11: 84,055,337 (GRCm39) |
V93A |
probably benign |
Het |
| Gm9989 |
T |
C |
3: 81,829,549 (GRCm39) |
|
noncoding transcript |
Het |
| Gsdmc4 |
A |
T |
15: 63,765,736 (GRCm39) |
|
probably null |
Het |
| Gvin3 |
T |
A |
7: 106,198,772 (GRCm39) |
|
noncoding transcript |
Het |
| Ighv10-1 |
A |
T |
12: 114,442,643 (GRCm39) |
M114K |
probably benign |
Het |
| Il22b |
T |
C |
10: 118,126,115 (GRCm39) |
I161V |
probably damaging |
Het |
| Itfg2 |
T |
A |
6: 128,387,413 (GRCm39) |
|
probably benign |
Het |
| Kirrel1 |
G |
A |
3: 86,995,774 (GRCm39) |
Q387* |
probably null |
Het |
| Klk1 |
C |
T |
7: 43,876,968 (GRCm39) |
R24* |
probably null |
Het |
| Klra7 |
T |
C |
6: 130,208,612 (GRCm39) |
|
probably null |
Het |
| Ltn1 |
T |
C |
16: 87,213,118 (GRCm39) |
Y481C |
possibly damaging |
Het |
| Man1c1 |
G |
C |
4: 134,430,749 (GRCm39) |
P11R |
probably damaging |
Het |
| Mrps2 |
A |
G |
2: 28,359,782 (GRCm39) |
N213S |
probably benign |
Het |
| Muc4 |
A |
T |
16: 32,569,869 (GRCm39) |
I310F |
possibly damaging |
Het |
| Ntrk3 |
T |
A |
7: 78,167,185 (GRCm39) |
Y102F |
probably damaging |
Het |
| Or8k24 |
A |
T |
2: 86,216,431 (GRCm39) |
C110* |
probably null |
Het |
| Otof |
C |
T |
5: 30,556,635 (GRCm39) |
G282D |
probably damaging |
Het |
| Pcdhb2 |
A |
T |
18: 37,430,367 (GRCm39) |
|
probably null |
Het |
| Pign |
A |
T |
1: 105,515,703 (GRCm39) |
|
probably null |
Het |
| Plekha6 |
G |
A |
1: 133,222,416 (GRCm39) |
E1001K |
probably benign |
Het |
| Plxna2 |
C |
T |
1: 194,431,625 (GRCm39) |
S538F |
probably damaging |
Het |
| Ppm1d |
A |
G |
11: 85,236,678 (GRCm39) |
T486A |
probably benign |
Het |
| Pudp |
A |
G |
18: 50,701,329 (GRCm39) |
F135L |
probably benign |
Het |
| Rd3l |
T |
G |
12: 111,945,945 (GRCm39) |
N178T |
probably benign |
Het |
| Rel |
A |
C |
11: 23,703,215 (GRCm39) |
|
probably null |
Het |
| Sf3a1 |
T |
A |
11: 4,117,824 (GRCm39) |
F195L |
probably damaging |
Het |
| Slc30a1 |
G |
C |
1: 191,639,401 (GRCm39) |
A95P |
probably damaging |
Het |
| Slc47a2 |
T |
C |
11: 61,194,773 (GRCm39) |
T469A |
probably benign |
Het |
| Slc4a10 |
A |
T |
2: 61,876,989 (GRCm39) |
M1L |
probably benign |
Het |
| Slc8a1 |
T |
A |
17: 81,955,703 (GRCm39) |
D445V |
probably damaging |
Het |
| Slc9a7 |
C |
T |
X: 20,071,793 (GRCm39) |
G113R |
probably damaging |
Het |
| Spata31e5 |
T |
A |
1: 28,816,712 (GRCm39) |
D440V |
probably damaging |
Het |
| Spic |
T |
C |
10: 88,511,545 (GRCm39) |
H237R |
possibly damaging |
Het |
| Stk26 |
A |
G |
X: 49,977,910 (GRCm39) |
E317G |
probably benign |
Het |
| Tex10 |
A |
T |
4: 48,459,355 (GRCm39) |
Y506* |
probably null |
Het |
| Trhde |
T |
A |
10: 114,280,585 (GRCm39) |
R848* |
probably null |
Het |
| Trpc5 |
T |
A |
X: 143,202,594 (GRCm39) |
R545* |
probably null |
Het |
| Usp24 |
C |
T |
4: 106,216,286 (GRCm39) |
T379M |
possibly damaging |
Het |
| Zfp783 |
A |
T |
6: 47,922,499 (GRCm39) |
|
noncoding transcript |
Het |
|
| Other mutations in Dync2i2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL02007:Dync2i2
|
APN |
2 |
29,928,402 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL02165:Dync2i2
|
APN |
2 |
29,922,172 (GRCm39) |
missense |
probably benign |
|
|
IGL02600:Dync2i2
|
APN |
2 |
29,923,314 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
PIT1430001:Dync2i2
|
UTSW |
2 |
29,922,147 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0542:Dync2i2
|
UTSW |
2 |
29,921,837 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4065:Dync2i2
|
UTSW |
2 |
29,922,820 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4750:Dync2i2
|
UTSW |
2 |
29,923,932 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4907:Dync2i2
|
UTSW |
2 |
29,922,472 (GRCm39) |
splice site |
probably null |
|
|
R5008:Dync2i2
|
UTSW |
2 |
29,922,781 (GRCm39) |
missense |
probably benign |
0.14 |
|
R5253:Dync2i2
|
UTSW |
2 |
29,922,375 (GRCm39) |
unclassified |
probably benign |
|
|
R6014:Dync2i2
|
UTSW |
2 |
29,921,763 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6456:Dync2i2
|
UTSW |
2 |
29,922,779 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6789:Dync2i2
|
UTSW |
2 |
29,923,284 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7024:Dync2i2
|
UTSW |
2 |
29,928,278 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R7319:Dync2i2
|
UTSW |
2 |
29,928,341 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7576:Dync2i2
|
UTSW |
2 |
29,938,790 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7640:Dync2i2
|
UTSW |
2 |
29,921,780 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8025:Dync2i2
|
UTSW |
2 |
29,938,730 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8111:Dync2i2
|
UTSW |
2 |
29,921,859 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8273:Dync2i2
|
UTSW |
2 |
29,921,903 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8277:Dync2i2
|
UTSW |
2 |
29,923,886 (GRCm39) |
missense |
probably benign |
|
|
R8309:Dync2i2
|
UTSW |
2 |
29,922,201 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8724:Dync2i2
|
UTSW |
2 |
29,923,961 (GRCm39) |
missense |
probably benign |
0.11 |
|
R8732:Dync2i2
|
UTSW |
2 |
29,922,220 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8837:Dync2i2
|
UTSW |
2 |
29,928,374 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9149:Dync2i2
|
UTSW |
2 |
29,923,953 (GRCm39) |
missense |
probably benign |
0.26 |
|
R9190:Dync2i2
|
UTSW |
2 |
29,922,211 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9557:Dync2i2
|
UTSW |
2 |
29,922,534 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGGAGAAGGCCACTGATGTC -3'
(R):5'- ATTCTTTACTCTTACAGCTGGGG -3'
Sequencing Primer
(F):5'- ACCTCAGTCTCTCCACGGG -3'
(R):5'- GGGGGTGAGGCTGATACTG -3'
|
| Posted On |
2015-05-15 |
Incidental Mutation