Incidental Mutation 'R4695:Apc2'
| ID |
355640 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Apc2
|
| Ensembl Gene |
ENSMUSG00000020135 |
| Gene Name |
APC regulator of WNT signaling pathway 2 |
| Synonyms |
APCL |
| MMRRC Submission |
042016-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.172)
|
| Stock # |
R4695 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
10 |
| Chromosomal Location |
80131811-80154097 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to A
at 80146877 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Arginine to Serine
at position 615
(R615S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000020349
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000020349]
[ENSMUST00000105359]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000020349
AA Change: R615S
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000020349
Gene: ENSMUSG00000020135
AA Change: R615S
| Domain | Start | End | E-Value | Type |
|---|
|
PDB:1DEB|B
|
4 |
57 |
9e-17 |
PDB |
|
Pfam:Suppressor_APC
|
123 |
205 |
1.3e-28 |
PFAM |
|
coiled coil region
|
214 |
236 |
N/A |
INTRINSIC |
|
low complexity region
|
242 |
261 |
N/A |
INTRINSIC |
|
ARM
|
300 |
355 |
2.95e0 |
SMART |
|
ARM
|
417 |
468 |
2.22e-2 |
SMART |
|
ARM
|
470 |
511 |
3.22e0 |
SMART |
|
ARM
|
513 |
555 |
3.56e-1 |
SMART |
|
ARM
|
557 |
602 |
2.1e1 |
SMART |
|
ARM
|
607 |
647 |
1.82e-7 |
SMART |
|
Blast:ARM
|
649 |
689 |
6e-18 |
BLAST |
|
low complexity region
|
772 |
792 |
N/A |
INTRINSIC |
|
low complexity region
|
817 |
844 |
N/A |
INTRINSIC |
|
low complexity region
|
859 |
870 |
N/A |
INTRINSIC |
|
low complexity region
|
971 |
980 |
N/A |
INTRINSIC |
|
low complexity region
|
1057 |
1069 |
N/A |
INTRINSIC |
|
low complexity region
|
1087 |
1103 |
N/A |
INTRINSIC |
|
Pfam:APC_crr
|
1134 |
1159 |
4.4e-9 |
PFAM |
|
low complexity region
|
1197 |
1208 |
N/A |
INTRINSIC |
|
Pfam:APC_crr
|
1244 |
1269 |
4.1e-8 |
PFAM |
|
Pfam:SAMP
|
1323 |
1343 |
2.1e-10 |
PFAM |
|
Pfam:APC_crr
|
1369 |
1394 |
5.8e-8 |
PFAM |
|
low complexity region
|
1500 |
1516 |
N/A |
INTRINSIC |
|
Pfam:APC_crr
|
1540 |
1565 |
5.7e-8 |
PFAM |
|
Pfam:SAMP
|
1594 |
1613 |
8.8e-11 |
PFAM |
|
low complexity region
|
1673 |
1699 |
N/A |
INTRINSIC |
|
Pfam:APC_basic
|
1757 |
2093 |
1.1e-142 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000105359
AA Change: R644S
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000100996
Gene: ENSMUSG00000020135
AA Change: R644S
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
Pfam:APC_N_CC
|
30 |
81 |
2.7e-34 |
PFAM |
|
Pfam:Suppressor_APC
|
148 |
228 |
1.4e-27 |
PFAM |
|
coiled coil region
|
238 |
260 |
N/A |
INTRINSIC |
|
low complexity region
|
266 |
285 |
N/A |
INTRINSIC |
|
ARM
|
324 |
379 |
2.95e0 |
SMART |
|
ARM
|
446 |
497 |
2.22e-2 |
SMART |
|
ARM
|
499 |
540 |
3.22e0 |
SMART |
|
ARM
|
542 |
584 |
3.56e-1 |
SMART |
|
ARM
|
586 |
631 |
2.1e1 |
SMART |
|
ARM
|
636 |
676 |
1.82e-7 |
SMART |
|
Blast:ARM
|
678 |
718 |
6e-18 |
BLAST |
|
Pfam:Arm_APC_u3
|
719 |
977 |
1.1e-26 |
PFAM |
|
low complexity region
|
1000 |
1009 |
N/A |
INTRINSIC |
|
low complexity region
|
1086 |
1098 |
N/A |
INTRINSIC |
|
low complexity region
|
1116 |
1132 |
N/A |
INTRINSIC |
|
Pfam:APC_crr
|
1164 |
1187 |
9.3e-8 |
PFAM |
|
low complexity region
|
1226 |
1237 |
N/A |
INTRINSIC |
|
Pfam:APC_crr
|
1274 |
1297 |
7.9e-10 |
PFAM |
|
Pfam:APC_crr
|
1399 |
1423 |
1.3e-9 |
PFAM |
|
low complexity region
|
1529 |
1545 |
N/A |
INTRINSIC |
|
low complexity region
|
1585 |
1603 |
N/A |
INTRINSIC |
|
Pfam:SAMP
|
1624 |
1642 |
1.3e-11 |
PFAM |
|
low complexity region
|
1702 |
1728 |
N/A |
INTRINSIC |
|
Pfam:APC_basic
|
1786 |
2122 |
1.3e-122 |
PFAM |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.1%
- 20x: 95.0%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a null allele display gradual postnatal growth retardation, abnormal lamination of the cerebral cortex, hippocampus, olfactory bulb and cerebellum, impaired neuronal migration and impaired coordination. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 68 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adamts10 |
T |
A |
17: 33,750,713 (GRCm39) |
M251K |
possibly damaging |
Het |
| Adcy2 |
A |
T |
13: 68,875,962 (GRCm39) |
H513Q |
possibly damaging |
Het |
| Afg2a |
T |
G |
3: 37,512,474 (GRCm39) |
F713C |
probably damaging |
Het |
| Ahctf1 |
A |
G |
1: 179,580,619 (GRCm39) |
L1861P |
possibly damaging |
Het |
| Arhgap45 |
A |
C |
10: 79,861,364 (GRCm39) |
D509A |
probably damaging |
Het |
| Atp6v1c2 |
T |
C |
12: 17,351,208 (GRCm39) |
T108A |
probably benign |
Het |
| Blm |
T |
A |
7: 80,143,976 (GRCm39) |
D821V |
probably damaging |
Het |
| C3 |
T |
A |
17: 57,528,057 (GRCm39) |
I721L |
probably benign |
Het |
| Ccdc13 |
A |
T |
9: 121,649,826 (GRCm39) |
V207E |
probably damaging |
Het |
| Ccndbp1 |
C |
T |
2: 120,845,208 (GRCm39) |
|
probably benign |
Het |
| Cd180 |
A |
C |
13: 102,842,268 (GRCm39) |
Q438P |
probably benign |
Het |
| Cd248 |
C |
T |
19: 5,118,473 (GRCm39) |
T107M |
probably damaging |
Het |
| Cdan1 |
G |
A |
2: 120,558,864 (GRCm39) |
R445C |
probably damaging |
Het |
| Cic |
C |
A |
7: 24,973,013 (GRCm39) |
H915N |
possibly damaging |
Het |
| Cox8c |
T |
C |
12: 102,865,742 (GRCm39) |
S40P |
possibly damaging |
Het |
| Cyp2d34 |
A |
T |
15: 82,501,092 (GRCm39) |
C347S |
probably benign |
Het |
| Dhx30 |
A |
T |
9: 109,914,356 (GRCm39) |
F974I |
probably damaging |
Het |
| Dlec1 |
A |
T |
9: 118,972,221 (GRCm39) |
T1414S |
probably benign |
Het |
| Dlg2 |
C |
A |
7: 92,087,170 (GRCm39) |
|
probably null |
Het |
| Dynlt5 |
T |
A |
4: 102,861,426 (GRCm39) |
I136K |
probably damaging |
Het |
| Dzip1l |
T |
A |
9: 99,529,258 (GRCm39) |
M329K |
probably benign |
Het |
| Dzip3 |
A |
T |
16: 48,771,924 (GRCm39) |
L582I |
probably damaging |
Het |
| Emilin2 |
T |
C |
17: 71,559,773 (GRCm39) |
Y1068C |
probably damaging |
Het |
| Fam221b |
T |
A |
4: 43,659,622 (GRCm39) |
|
probably null |
Het |
| Fbxw22 |
A |
G |
9: 109,207,939 (GRCm39) |
I444T |
probably damaging |
Het |
| Flnc |
T |
A |
6: 29,440,428 (GRCm39) |
N245K |
probably damaging |
Het |
| Fnip1 |
T |
A |
11: 54,390,245 (GRCm39) |
I380N |
probably damaging |
Het |
| Gbf1 |
C |
T |
19: 46,247,606 (GRCm39) |
R181* |
probably null |
Het |
| Igkv6-17 |
T |
A |
6: 70,348,486 (GRCm39) |
F12I |
probably benign |
Het |
| Itln1 |
C |
A |
1: 171,358,645 (GRCm39) |
G174V |
probably damaging |
Het |
| Lrrc52 |
A |
G |
1: 167,293,660 (GRCm39) |
|
probably null |
Het |
| LTO1 |
T |
C |
7: 144,482,715 (GRCm39) |
|
probably null |
Het |
| Matn2 |
A |
G |
15: 34,403,071 (GRCm39) |
Y432C |
probably damaging |
Het |
| Metap1d |
A |
G |
2: 71,355,305 (GRCm39) |
*336W |
probably null |
Het |
| Mgam2-ps |
T |
A |
6: 40,779,489 (GRCm39) |
|
noncoding transcript |
Het |
| Mrps9 |
T |
A |
1: 42,901,675 (GRCm39) |
V61D |
possibly damaging |
Het |
| Myh7b |
T |
C |
2: 155,456,097 (GRCm39) |
Y161H |
probably damaging |
Het |
| Myh9 |
T |
A |
15: 77,653,053 (GRCm39) |
D1428V |
probably damaging |
Het |
| N4bp3 |
A |
T |
11: 51,535,306 (GRCm39) |
|
probably null |
Het |
| Nat9 |
T |
A |
11: 115,075,416 (GRCm39) |
Q75L |
probably benign |
Het |
| Nop2 |
T |
C |
6: 125,121,519 (GRCm39) |
V767A |
probably benign |
Het |
| Ntrk2 |
A |
G |
13: 59,274,307 (GRCm39) |
K728E |
probably damaging |
Het |
| Or51e1 |
T |
G |
7: 102,358,764 (GRCm39) |
C99W |
probably damaging |
Het |
| Or5p72 |
G |
A |
7: 108,022,196 (GRCm39) |
M139I |
probably benign |
Het |
| Or7g21 |
T |
A |
9: 19,032,306 (GRCm39) |
H15Q |
probably null |
Het |
| Pcdhgb2 |
A |
G |
18: 37,825,375 (GRCm39) |
T789A |
probably benign |
Het |
| Pcyt2 |
T |
C |
11: 120,502,000 (GRCm39) |
D321G |
probably benign |
Het |
| Rad9a |
G |
A |
19: 4,250,560 (GRCm39) |
R85C |
probably damaging |
Het |
| Rbbp8 |
A |
T |
18: 11,854,839 (GRCm39) |
K355* |
probably null |
Het |
| Rhag |
T |
C |
17: 41,147,358 (GRCm39) |
Y407H |
probably damaging |
Het |
| Robo4 |
G |
A |
9: 37,314,495 (GRCm39) |
V161M |
probably damaging |
Het |
| Rpl27-ps3 |
C |
A |
18: 6,332,922 (GRCm39) |
N97K |
probably benign |
Het |
| Slc45a4 |
A |
G |
15: 73,453,924 (GRCm39) |
I691T |
possibly damaging |
Het |
| Slc9a9 |
A |
T |
9: 94,818,502 (GRCm39) |
|
probably benign |
Het |
| Stard13 |
A |
G |
5: 150,984,280 (GRCm39) |
F619L |
probably benign |
Het |
| Stt3b |
A |
T |
9: 115,083,862 (GRCm39) |
V438E |
probably damaging |
Het |
| Tacr3 |
C |
T |
3: 134,535,182 (GRCm39) |
T50I |
probably benign |
Het |
| Tacr3 |
G |
T |
3: 134,635,690 (GRCm39) |
C298F |
probably damaging |
Het |
| Taok3 |
C |
T |
5: 117,366,131 (GRCm39) |
T394M |
probably benign |
Het |
| Tgfb1i1 |
A |
G |
7: 127,848,348 (GRCm39) |
D128G |
probably damaging |
Het |
| Tgfbr3l |
G |
T |
8: 4,300,574 (GRCm39) |
V251L |
probably benign |
Het |
| Tom1l2 |
C |
G |
11: 60,161,259 (GRCm39) |
R84P |
probably damaging |
Het |
| Top3a |
A |
G |
11: 60,633,238 (GRCm39) |
S953P |
probably benign |
Het |
| Trappc10 |
T |
C |
10: 78,033,697 (GRCm39) |
K957E |
probably damaging |
Het |
| Ttn |
T |
A |
2: 76,565,668 (GRCm39) |
E28228V |
probably damaging |
Het |
| Ttn |
T |
A |
2: 76,585,168 (GRCm39) |
I22042F |
probably damaging |
Het |
| Vdr |
A |
T |
15: 97,756,801 (GRCm39) |
|
probably null |
Het |
| Zfp42 |
A |
T |
8: 43,749,168 (GRCm39) |
L111Q |
probably damaging |
Het |
|
| Other mutations in Apc2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01069:Apc2
|
APN |
10 |
80,147,820 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01154:Apc2
|
APN |
10 |
80,148,903 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL01411:Apc2
|
APN |
10 |
80,150,912 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01598:Apc2
|
APN |
10 |
80,148,882 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01621:Apc2
|
APN |
10 |
80,142,035 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01720:Apc2
|
APN |
10 |
80,150,333 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01837:Apc2
|
APN |
10 |
80,150,492 (GRCm39) |
missense |
probably benign |
0.24 |
|
IGL01933:Apc2
|
APN |
10 |
80,147,574 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02243:Apc2
|
APN |
10 |
80,138,175 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02292:Apc2
|
APN |
10 |
80,138,258 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
IGL02956:Apc2
|
APN |
10 |
80,142,209 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03081:Apc2
|
APN |
10 |
80,148,086 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03172:Apc2
|
APN |
10 |
80,149,220 (GRCm39) |
missense |
probably damaging |
0.98 |
|
LCD18:Apc2
|
UTSW |
10 |
80,135,808 (GRCm39) |
intron |
probably benign |
|
|
R0278:Apc2
|
UTSW |
10 |
80,148,647 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0501:Apc2
|
UTSW |
10 |
80,150,958 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0594:Apc2
|
UTSW |
10 |
80,142,090 (GRCm39) |
nonsense |
probably null |
|
|
R0607:Apc2
|
UTSW |
10 |
80,149,935 (GRCm39) |
missense |
probably benign |
|
|
R0624:Apc2
|
UTSW |
10 |
80,150,417 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0633:Apc2
|
UTSW |
10 |
80,143,289 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0638:Apc2
|
UTSW |
10 |
80,140,801 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0647:Apc2
|
UTSW |
10 |
80,140,762 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0830:Apc2
|
UTSW |
10 |
80,151,239 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1071:Apc2
|
UTSW |
10 |
80,147,336 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1221:Apc2
|
UTSW |
10 |
80,142,214 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1432:Apc2
|
UTSW |
10 |
80,148,183 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1579:Apc2
|
UTSW |
10 |
80,147,179 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1654:Apc2
|
UTSW |
10 |
80,137,676 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R1700:Apc2
|
UTSW |
10 |
80,148,603 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1774:Apc2
|
UTSW |
10 |
80,144,964 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1864:Apc2
|
UTSW |
10 |
80,149,482 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1908:Apc2
|
UTSW |
10 |
80,150,678 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1915:Apc2
|
UTSW |
10 |
80,151,701 (GRCm39) |
missense |
probably benign |
|
|
R1999:Apc2
|
UTSW |
10 |
80,144,994 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2050:Apc2
|
UTSW |
10 |
80,143,443 (GRCm39) |
splice site |
probably null |
|
|
R2219:Apc2
|
UTSW |
10 |
80,144,943 (GRCm39) |
missense |
probably benign |
0.41 |
|
R2393:Apc2
|
UTSW |
10 |
80,148,903 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R3862:Apc2
|
UTSW |
10 |
80,143,393 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R3900:Apc2
|
UTSW |
10 |
80,131,806 (GRCm39) |
splice site |
probably null |
|
|
R3901:Apc2
|
UTSW |
10 |
80,150,922 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R3952:Apc2
|
UTSW |
10 |
80,150,318 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4009:Apc2
|
UTSW |
10 |
80,149,426 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4090:Apc2
|
UTSW |
10 |
80,141,378 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4754:Apc2
|
UTSW |
10 |
80,150,192 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4807:Apc2
|
UTSW |
10 |
80,150,196 (GRCm39) |
missense |
probably benign |
0.13 |
|
R4886:Apc2
|
UTSW |
10 |
80,150,047 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4964:Apc2
|
UTSW |
10 |
80,149,841 (GRCm39) |
missense |
probably benign |
0.14 |
|
R5056:Apc2
|
UTSW |
10 |
80,137,148 (GRCm39) |
missense |
probably benign |
|
|
R5057:Apc2
|
UTSW |
10 |
80,144,903 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5165:Apc2
|
UTSW |
10 |
80,151,684 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5241:Apc2
|
UTSW |
10 |
80,148,068 (GRCm39) |
missense |
probably benign |
|
|
R5649:Apc2
|
UTSW |
10 |
80,149,972 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5924:Apc2
|
UTSW |
10 |
80,147,984 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6124:Apc2
|
UTSW |
10 |
80,142,185 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6218:Apc2
|
UTSW |
10 |
80,142,254 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6376:Apc2
|
UTSW |
10 |
80,148,488 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6490:Apc2
|
UTSW |
10 |
80,149,757 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6572:Apc2
|
UTSW |
10 |
80,147,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6620:Apc2
|
UTSW |
10 |
80,149,401 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7171:Apc2
|
UTSW |
10 |
80,151,170 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R7180:Apc2
|
UTSW |
10 |
80,146,990 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7326:Apc2
|
UTSW |
10 |
80,147,574 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7340:Apc2
|
UTSW |
10 |
80,149,316 (GRCm39) |
missense |
probably benign |
0.12 |
|
R7378:Apc2
|
UTSW |
10 |
80,147,228 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7384:Apc2
|
UTSW |
10 |
80,148,458 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7431:Apc2
|
UTSW |
10 |
80,138,017 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R7543:Apc2
|
UTSW |
10 |
80,150,720 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R7743:Apc2
|
UTSW |
10 |
80,140,749 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7759:Apc2
|
UTSW |
10 |
80,147,030 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8244:Apc2
|
UTSW |
10 |
80,151,166 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8327:Apc2
|
UTSW |
10 |
80,137,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8489:Apc2
|
UTSW |
10 |
80,143,298 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8494:Apc2
|
UTSW |
10 |
80,150,313 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8669:Apc2
|
UTSW |
10 |
80,149,491 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8773:Apc2
|
UTSW |
10 |
80,142,046 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8920:Apc2
|
UTSW |
10 |
80,149,934 (GRCm39) |
missense |
probably benign |
|
|
R9178:Apc2
|
UTSW |
10 |
80,150,235 (GRCm39) |
missense |
probably benign |
0.11 |
|
R9224:Apc2
|
UTSW |
10 |
80,150,111 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9357:Apc2
|
UTSW |
10 |
80,146,872 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9394:Apc2
|
UTSW |
10 |
80,145,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9666:Apc2
|
UTSW |
10 |
80,147,183 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R9689:Apc2
|
UTSW |
10 |
80,150,733 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0018:Apc2
|
UTSW |
10 |
80,148,098 (GRCm39) |
missense |
probably benign |
0.02 |
|
Z1177:Apc2
|
UTSW |
10 |
80,147,870 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATGGGTGGGCATGACTGAAC -3'
(R):5'- ACCCATGGCGATCATCTTG -3'
Sequencing Primer
(F):5'- GCTAGAGGAGTGGCTGAGTC -3'
(R):5'- CCCATGGCGATCATCTTGTGTTTG -3'
|
| Posted On |
2015-10-21 |
Incidental Mutation