Incidental Mutation 'R4786:Thada'
| ID |
367136 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Thada
|
| Ensembl Gene |
ENSMUSG00000024251 |
| Gene Name |
thyroid adenoma associated |
| Synonyms |
|
| MMRRC Submission |
041995-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4786 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
17 |
| Chromosomal Location |
84497504-84773633 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 84766283 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Histidine to Leucine
at position 41
(H41L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000041701
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000047524]
|
| AlphaFold |
A8C756 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000047524
AA Change: H41L
PolyPhen 2
Score 0.660 (Sensitivity: 0.86; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000041701
Gene: ENSMUSG00000024251
AA Change: H41L
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1gw5a_
|
457 |
926 |
3e-6 |
SMART |
|
Pfam:DUF2428
|
938 |
1239 |
1.6e-93 |
PFAM |
|
SCOP:d1gw5a_
|
1343 |
1802 |
7e-6 |
SMART |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.0%
- 20x: 94.7%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene is the target of 2p21 choromosomal aberrations in benign thyroid adenomas. Single nucleotide polymorphisms (SNPs) in this gene may be associated with type 2 diabetes and polycystic ovary syndrome. The encoded protein is likely involved in the death receptor pathway and apoptosis. [provided by RefSeq, Sep 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 86 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2700097O09Rik |
A |
T |
12: 55,106,321 (GRCm39) |
I134N |
possibly damaging |
Het |
| Acvr1c |
T |
C |
2: 58,170,366 (GRCm39) |
Y414C |
probably damaging |
Het |
| Adam32 |
A |
C |
8: 25,353,509 (GRCm39) |
S693R |
probably damaging |
Het |
| Aldh2 |
A |
T |
5: 121,710,887 (GRCm39) |
F314Y |
probably benign |
Het |
| Anks1 |
A |
G |
17: 28,271,704 (GRCm39) |
D874G |
possibly damaging |
Het |
| Ap4b1 |
T |
A |
3: 103,726,120 (GRCm39) |
V372E |
probably benign |
Het |
| Aqp12 |
G |
A |
1: 92,934,177 (GRCm39) |
C18Y |
probably damaging |
Het |
| Arap1 |
T |
A |
7: 101,034,212 (GRCm39) |
I218N |
possibly damaging |
Het |
| Arhgap42 |
C |
A |
9: 9,238,703 (GRCm39) |
E28* |
probably null |
Het |
| Asb5 |
G |
A |
8: 55,038,874 (GRCm39) |
E247K |
probably benign |
Het |
| Atg9b |
T |
C |
5: 24,591,087 (GRCm39) |
D781G |
possibly damaging |
Het |
| Atxn10 |
A |
G |
15: 85,271,344 (GRCm39) |
H294R |
probably benign |
Het |
| Bod1l |
G |
T |
5: 41,976,781 (GRCm39) |
T1511K |
probably benign |
Het |
| Btnl2 |
A |
T |
17: 34,582,322 (GRCm39) |
N296I |
probably damaging |
Het |
| Camta1 |
A |
T |
4: 151,374,496 (GRCm39) |
L168H |
probably damaging |
Het |
| Cant1 |
A |
T |
11: 118,299,665 (GRCm39) |
V265E |
possibly damaging |
Het |
| Ccdc157 |
T |
C |
11: 4,101,861 (GRCm39) |
D20G |
probably damaging |
Het |
| Cd209c |
T |
G |
8: 3,995,698 (GRCm39) |
T35P |
possibly damaging |
Het |
| Cdc20b |
G |
A |
13: 113,215,268 (GRCm39) |
V279M |
probably damaging |
Het |
| Cdh18 |
T |
A |
15: 23,410,873 (GRCm39) |
W453R |
probably null |
Het |
| Cdh24 |
A |
G |
14: 54,875,007 (GRCm39) |
S333P |
possibly damaging |
Het |
| Ceacam11 |
T |
C |
7: 17,706,239 (GRCm39) |
|
probably null |
Het |
| Ciz1 |
C |
T |
2: 32,267,539 (GRCm39) |
P150L |
probably damaging |
Het |
| Crip3 |
C |
A |
17: 46,741,968 (GRCm39) |
Q152K |
possibly damaging |
Het |
| Dars2 |
G |
A |
1: 160,888,330 (GRCm39) |
R197W |
probably damaging |
Het |
| Dctn4 |
A |
G |
18: 60,688,267 (GRCm39) |
D394G |
probably damaging |
Het |
| Dido1 |
T |
C |
2: 180,312,664 (GRCm39) |
Y1077C |
possibly damaging |
Het |
| Dnhd1 |
A |
G |
7: 105,323,651 (GRCm39) |
T641A |
probably benign |
Het |
| Egln3 |
A |
T |
12: 54,232,367 (GRCm39) |
I146N |
probably damaging |
Het |
| Eif2ak3 |
C |
T |
6: 70,869,602 (GRCm39) |
T763M |
possibly damaging |
Het |
| Etfbkmt |
A |
T |
6: 149,048,744 (GRCm39) |
M1L |
probably benign |
Het |
| Fam171a1 |
A |
T |
2: 3,226,615 (GRCm39) |
I583F |
probably damaging |
Het |
| Fbxo38 |
A |
C |
18: 62,662,745 (GRCm39) |
L249W |
probably damaging |
Het |
| Fxyd5 |
T |
C |
7: 30,740,907 (GRCm39) |
|
probably benign |
Het |
| Gabrr3 |
C |
A |
16: 59,250,463 (GRCm39) |
T154K |
probably benign |
Het |
| Gm7233 |
C |
A |
14: 43,038,347 (GRCm39) |
D90E |
probably benign |
Het |
| Gm8186 |
A |
G |
17: 26,318,014 (GRCm39) |
V61A |
probably benign |
Het |
| Gnao1 |
A |
G |
8: 94,670,931 (GRCm39) |
I137V |
probably benign |
Het |
| Gnptab |
A |
G |
10: 88,272,044 (GRCm39) |
M945V |
probably damaging |
Het |
| Gpsm1 |
G |
A |
2: 26,212,493 (GRCm39) |
A78T |
probably benign |
Het |
| Gtf2b |
T |
C |
3: 142,487,230 (GRCm39) |
L222P |
probably damaging |
Het |
| Hnrnpf |
A |
G |
6: 117,900,857 (GRCm39) |
Y47C |
probably damaging |
Het |
| Itga6 |
A |
G |
2: 71,669,034 (GRCm39) |
N608S |
possibly damaging |
Het |
| Kdm2b |
T |
C |
5: 123,018,917 (GRCm39) |
|
probably null |
Het |
| Krit1 |
T |
A |
5: 3,862,467 (GRCm39) |
H207Q |
possibly damaging |
Het |
| Ky |
A |
G |
9: 102,419,186 (GRCm39) |
N398D |
probably benign |
Het |
| Lama1 |
T |
A |
17: 68,080,854 (GRCm39) |
V1294E |
possibly damaging |
Het |
| Lef1 |
C |
T |
3: 130,905,173 (GRCm39) |
T18I |
probably damaging |
Het |
| Lrp2 |
T |
C |
2: 69,368,300 (GRCm39) |
N178S |
probably damaging |
Het |
| Lrrc36 |
A |
G |
8: 106,181,910 (GRCm39) |
T525A |
probably benign |
Het |
| Map3k8 |
A |
T |
18: 4,340,647 (GRCm39) |
C222* |
probably null |
Het |
| Mapre2 |
G |
C |
18: 24,011,016 (GRCm39) |
S199T |
probably benign |
Het |
| Mcm3ap |
A |
G |
10: 76,324,300 (GRCm39) |
N911S |
probably benign |
Het |
| Mroh4 |
G |
T |
15: 74,482,083 (GRCm39) |
H722Q |
probably benign |
Het |
| Muc21 |
A |
T |
17: 35,930,221 (GRCm39) |
|
probably benign |
Het |
| Myo5b |
A |
C |
18: 74,828,451 (GRCm39) |
Y701S |
probably benign |
Het |
| Myt1l |
G |
T |
12: 29,861,457 (GRCm39) |
V80L |
unknown |
Het |
| Ncoa7 |
C |
A |
10: 30,531,638 (GRCm39) |
V24L |
probably benign |
Het |
| Nlrp10 |
A |
T |
7: 108,524,445 (GRCm39) |
V345D |
probably damaging |
Het |
| Nmral1 |
C |
A |
16: 4,534,288 (GRCm39) |
G51V |
probably damaging |
Het |
| Npc1 |
A |
G |
18: 12,332,554 (GRCm39) |
I797T |
probably benign |
Het |
| Or4x6 |
A |
T |
2: 89,949,351 (GRCm39) |
I197N |
possibly damaging |
Het |
| Or8g22 |
T |
A |
9: 38,958,783 (GRCm39) |
R22* |
probably null |
Het |
| Or8g34 |
A |
T |
9: 39,373,137 (GRCm39) |
I134L |
probably benign |
Het |
| Pclo |
A |
T |
5: 14,773,281 (GRCm39) |
I4419F |
unknown |
Het |
| Phf3 |
C |
A |
1: 30,855,638 (GRCm39) |
E983* |
probably null |
Het |
| Pitpnm2 |
A |
T |
5: 124,259,806 (GRCm39) |
Y1149* |
probably null |
Het |
| Sdc3 |
A |
T |
4: 130,550,079 (GRCm39) |
T430S |
probably damaging |
Het |
| Sema3f |
A |
G |
9: 107,559,881 (GRCm39) |
V671A |
probably benign |
Het |
| Sigirr |
T |
G |
7: 140,671,346 (GRCm39) |
S379R |
probably benign |
Het |
| Slc25a23 |
T |
A |
17: 57,354,326 (GRCm39) |
N360I |
possibly damaging |
Het |
| Slco6c1 |
A |
T |
1: 97,015,720 (GRCm39) |
M357K |
probably benign |
Het |
| Sox14 |
C |
A |
9: 99,757,018 (GRCm39) |
M240I |
probably benign |
Het |
| Stradb |
A |
T |
1: 59,030,367 (GRCm39) |
|
probably benign |
Het |
| Szt2 |
A |
T |
4: 118,256,259 (GRCm39) |
M200K |
probably benign |
Het |
| Tef |
T |
C |
15: 81,699,453 (GRCm39) |
S85P |
probably benign |
Het |
| Tinagl1 |
A |
G |
4: 130,067,724 (GRCm39) |
F90S |
probably benign |
Het |
| Tnfaip1 |
G |
A |
11: 78,421,045 (GRCm39) |
T5I |
possibly damaging |
Het |
| Tnfrsf23 |
A |
T |
7: 143,233,801 (GRCm39) |
V59D |
probably damaging |
Het |
| Tnpo3 |
A |
G |
6: 29,578,541 (GRCm39) |
V311A |
probably benign |
Het |
| Trak1 |
T |
A |
9: 121,301,560 (GRCm39) |
M772K |
probably benign |
Het |
| Ubash3a |
A |
G |
17: 31,436,938 (GRCm39) |
D185G |
probably benign |
Het |
| Vmn2r120 |
T |
C |
17: 57,829,048 (GRCm39) |
T516A |
probably benign |
Het |
| Wdr4 |
A |
C |
17: 31,728,785 (GRCm39) |
L130R |
probably damaging |
Het |
| Zfp12 |
T |
C |
5: 143,231,257 (GRCm39) |
I528T |
probably damaging |
Het |
| Zfp607a |
T |
C |
7: 27,578,838 (GRCm39) |
L636P |
probably damaging |
Het |
|
| Other mutations in Thada |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00672:Thada
|
APN |
17 |
84,751,646 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL00902:Thada
|
APN |
17 |
84,755,404 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01634:Thada
|
APN |
17 |
84,700,786 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01689:Thada
|
APN |
17 |
84,754,116 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
IGL01693:Thada
|
APN |
17 |
84,754,072 (GRCm39) |
missense |
probably benign |
|
|
IGL01937:Thada
|
APN |
17 |
84,530,194 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01945:Thada
|
APN |
17 |
84,530,194 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02231:Thada
|
APN |
17 |
84,736,125 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02951:Thada
|
APN |
17 |
84,751,456 (GRCm39) |
missense |
probably benign |
0.16 |
|
IGL03167:Thada
|
APN |
17 |
84,766,277 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL03279:Thada
|
APN |
17 |
84,742,988 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03347:Thada
|
APN |
17 |
84,705,633 (GRCm39) |
missense |
probably damaging |
1.00 |
|
H8562:Thada
|
UTSW |
17 |
84,753,972 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03098:Thada
|
UTSW |
17 |
84,641,569 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0006:Thada
|
UTSW |
17 |
84,533,468 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0052:Thada
|
UTSW |
17 |
84,762,586 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0052:Thada
|
UTSW |
17 |
84,762,586 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0357:Thada
|
UTSW |
17 |
84,538,364 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0388:Thada
|
UTSW |
17 |
84,538,524 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0543:Thada
|
UTSW |
17 |
84,730,591 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0606:Thada
|
UTSW |
17 |
84,723,731 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0630:Thada
|
UTSW |
17 |
84,536,603 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0664:Thada
|
UTSW |
17 |
84,644,257 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0855:Thada
|
UTSW |
17 |
84,744,083 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0972:Thada
|
UTSW |
17 |
84,736,490 (GRCm39) |
splice site |
probably benign |
|
|
R1297:Thada
|
UTSW |
17 |
84,559,863 (GRCm39) |
splice site |
probably benign |
|
|
R1465:Thada
|
UTSW |
17 |
84,744,104 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1465:Thada
|
UTSW |
17 |
84,744,104 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1490:Thada
|
UTSW |
17 |
84,754,029 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R1789:Thada
|
UTSW |
17 |
84,755,462 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1789:Thada
|
UTSW |
17 |
84,755,461 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1802:Thada
|
UTSW |
17 |
84,771,835 (GRCm39) |
missense |
probably benign |
0.34 |
|
R1831:Thada
|
UTSW |
17 |
84,538,542 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1834:Thada
|
UTSW |
17 |
84,533,432 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R1881:Thada
|
UTSW |
17 |
84,744,130 (GRCm39) |
missense |
probably benign |
0.19 |
|
R1925:Thada
|
UTSW |
17 |
84,751,927 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1969:Thada
|
UTSW |
17 |
84,617,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1970:Thada
|
UTSW |
17 |
84,617,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1971:Thada
|
UTSW |
17 |
84,617,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2149:Thada
|
UTSW |
17 |
84,749,192 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2191:Thada
|
UTSW |
17 |
84,753,949 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2571:Thada
|
UTSW |
17 |
84,762,068 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3405:Thada
|
UTSW |
17 |
84,538,213 (GRCm39) |
splice site |
probably benign |
|
|
R3406:Thada
|
UTSW |
17 |
84,538,213 (GRCm39) |
splice site |
probably benign |
|
|
R3916:Thada
|
UTSW |
17 |
84,749,210 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4044:Thada
|
UTSW |
17 |
84,749,135 (GRCm39) |
missense |
probably benign |
0.41 |
|
R4461:Thada
|
UTSW |
17 |
84,733,665 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4662:Thada
|
UTSW |
17 |
84,743,078 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4696:Thada
|
UTSW |
17 |
84,733,614 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R4803:Thada
|
UTSW |
17 |
84,580,245 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4835:Thada
|
UTSW |
17 |
84,748,532 (GRCm39) |
splice site |
probably null |
|
|
R4872:Thada
|
UTSW |
17 |
84,754,027 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4898:Thada
|
UTSW |
17 |
84,755,470 (GRCm39) |
splice site |
probably null |
|
|
R4903:Thada
|
UTSW |
17 |
84,559,828 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R4929:Thada
|
UTSW |
17 |
84,751,654 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4959:Thada
|
UTSW |
17 |
84,751,611 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5071:Thada
|
UTSW |
17 |
84,693,960 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5092:Thada
|
UTSW |
17 |
84,751,896 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5398:Thada
|
UTSW |
17 |
84,733,614 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5480:Thada
|
UTSW |
17 |
84,739,682 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5552:Thada
|
UTSW |
17 |
84,736,558 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5575:Thada
|
UTSW |
17 |
84,723,827 (GRCm39) |
splice site |
probably null |
|
|
R5623:Thada
|
UTSW |
17 |
84,499,411 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5688:Thada
|
UTSW |
17 |
84,759,155 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5704:Thada
|
UTSW |
17 |
84,538,329 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6008:Thada
|
UTSW |
17 |
84,744,062 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6013:Thada
|
UTSW |
17 |
84,580,228 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6072:Thada
|
UTSW |
17 |
84,499,434 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R6156:Thada
|
UTSW |
17 |
84,700,795 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6243:Thada
|
UTSW |
17 |
84,744,030 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6449:Thada
|
UTSW |
17 |
84,736,601 (GRCm39) |
missense |
probably benign |
|
|
R6453:Thada
|
UTSW |
17 |
84,723,751 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6474:Thada
|
UTSW |
17 |
84,751,339 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R6732:Thada
|
UTSW |
17 |
84,761,842 (GRCm39) |
splice site |
probably null |
|
|
R6907:Thada
|
UTSW |
17 |
84,700,897 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7117:Thada
|
UTSW |
17 |
84,538,214 (GRCm39) |
splice site |
probably null |
|
|
R7167:Thada
|
UTSW |
17 |
84,538,391 (GRCm39) |
missense |
probably benign |
|
|
R7221:Thada
|
UTSW |
17 |
84,771,794 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7470:Thada
|
UTSW |
17 |
84,533,469 (GRCm39) |
missense |
probably benign |
|
|
R7753:Thada
|
UTSW |
17 |
84,559,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7809:Thada
|
UTSW |
17 |
84,759,265 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R7882:Thada
|
UTSW |
17 |
84,736,624 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7971:Thada
|
UTSW |
17 |
84,580,197 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R8004:Thada
|
UTSW |
17 |
84,499,633 (GRCm39) |
missense |
probably benign |
|
|
R8153:Thada
|
UTSW |
17 |
84,700,855 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8254:Thada
|
UTSW |
17 |
84,533,468 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8426:Thada
|
UTSW |
17 |
84,530,131 (GRCm39) |
missense |
probably benign |
0.17 |
|
R8438:Thada
|
UTSW |
17 |
84,743,057 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8670:Thada
|
UTSW |
17 |
84,739,774 (GRCm39) |
missense |
probably benign |
0.16 |
|
R8679:Thada
|
UTSW |
17 |
84,536,637 (GRCm39) |
missense |
probably benign |
0.28 |
|
R8952:Thada
|
UTSW |
17 |
84,736,524 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8983:Thada
|
UTSW |
17 |
84,538,515 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9009:Thada
|
UTSW |
17 |
84,759,203 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R9050:Thada
|
UTSW |
17 |
84,736,629 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9091:Thada
|
UTSW |
17 |
84,538,589 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9225:Thada
|
UTSW |
17 |
84,749,172 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9251:Thada
|
UTSW |
17 |
84,538,564 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9270:Thada
|
UTSW |
17 |
84,538,589 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9299:Thada
|
UTSW |
17 |
84,749,205 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9337:Thada
|
UTSW |
17 |
84,749,205 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9360:Thada
|
UTSW |
17 |
84,499,410 (GRCm39) |
missense |
probably benign |
|
|
R9416:Thada
|
UTSW |
17 |
84,766,292 (GRCm39) |
nonsense |
probably null |
|
|
R9484:Thada
|
UTSW |
17 |
84,736,619 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9584:Thada
|
UTSW |
17 |
84,733,605 (GRCm39) |
missense |
probably benign |
|
|
R9631:Thada
|
UTSW |
17 |
84,538,584 (GRCm39) |
missense |
probably benign |
0.17 |
|
Z1176:Thada
|
UTSW |
17 |
84,751,858 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
| Predicted Primers |
PCR Primer
(F):5'- CTATTGCTGCTCTGAATAAAAGGAC -3'
(R):5'- TTCACAGCAGTGCAGTGCAG -3'
Sequencing Primer
(F):5'- CAACCAAACCTGTCAGTT -3'
(R):5'- ATGTGCTTGCCCTGACACAG -3'
|
| Posted On |
2015-12-29 |
Incidental Mutation