Incidental Mutation 'R0606:Thada'
| ID |
54189 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Thada
|
| Ensembl Gene |
ENSMUSG00000024251 |
| Gene Name |
thyroid adenoma associated |
| Synonyms |
|
| MMRRC Submission |
038795-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R0606 (G1)
|
| Quality Score |
193 |
|
Status
|
Validated
|
| Chromosome |
17 |
| Chromosomal Location |
84497504-84773633 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to A
at 84723731 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Leucine
at position 1108
(V1108L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000041701
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000047524]
|
| AlphaFold |
A8C756 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000047524
AA Change: V1108L
PolyPhen 2
Score 0.897 (Sensitivity: 0.82; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000041701
Gene: ENSMUSG00000024251
AA Change: V1108L
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1gw5a_
|
457 |
926 |
3e-6 |
SMART |
|
Pfam:DUF2428
|
938 |
1239 |
1.6e-93 |
PFAM |
|
SCOP:d1gw5a_
|
1343 |
1802 |
7e-6 |
SMART |
|
| Meta Mutation Damage Score |
0.0895 |
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.8%
- 10x: 97.3%
- 20x: 94.2%
|
| Validation Efficiency |
98% (99/101) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene is the target of 2p21 choromosomal aberrations in benign thyroid adenomas. Single nucleotide polymorphisms (SNPs) in this gene may be associated with type 2 diabetes and polycystic ovary syndrome. The encoded protein is likely involved in the death receptor pathway and apoptosis. [provided by RefSeq, Sep 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 95 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Actl9 |
T |
C |
17: 33,652,572 (GRCm39) |
Y211H |
probably damaging |
Het |
| Actn1 |
A |
T |
12: 80,221,421 (GRCm39) |
|
probably benign |
Het |
| Adtrp |
A |
G |
13: 41,920,881 (GRCm39) |
F197L |
probably damaging |
Het |
| Ankrd11 |
G |
A |
8: 123,619,571 (GRCm39) |
T1406I |
probably benign |
Het |
| Arhgap24 |
A |
T |
5: 103,045,086 (GRCm39) |
R620W |
probably damaging |
Het |
| Atg13 |
A |
G |
2: 91,512,418 (GRCm39) |
Y284H |
probably benign |
Het |
| Atrn |
A |
G |
2: 130,748,776 (GRCm39) |
E99G |
possibly damaging |
Het |
| Cage1 |
A |
T |
13: 38,200,470 (GRCm39) |
|
probably benign |
Het |
| Cblif |
A |
T |
19: 11,729,658 (GRCm39) |
I206F |
possibly damaging |
Het |
| Ccr3 |
T |
A |
9: 123,828,839 (GRCm39) |
M58K |
probably benign |
Het |
| Cdk18 |
G |
T |
1: 132,045,355 (GRCm39) |
|
probably benign |
Het |
| Chst5 |
A |
G |
8: 112,617,551 (GRCm39) |
V23A |
probably benign |
Het |
| Col4a3 |
T |
C |
1: 82,650,307 (GRCm39) |
|
probably benign |
Het |
| Col4a6 |
A |
G |
X: 139,975,219 (GRCm39) |
|
probably benign |
Het |
| Csmd3 |
T |
C |
15: 48,321,058 (GRCm39) |
I251V |
probably benign |
Het |
| Csnk1g3 |
G |
A |
18: 54,050,100 (GRCm39) |
V115M |
probably damaging |
Het |
| Cst7 |
A |
T |
2: 150,412,439 (GRCm39) |
M1L |
probably benign |
Het |
| Cyp4f17 |
A |
T |
17: 32,746,817 (GRCm39) |
D373V |
probably damaging |
Het |
| Dclk2 |
G |
A |
3: 86,813,311 (GRCm39) |
R212W |
probably damaging |
Het |
| Dhrs7b |
T |
G |
11: 60,721,572 (GRCm39) |
|
probably benign |
Het |
| Dhx58 |
T |
A |
11: 100,593,077 (GRCm39) |
H210L |
probably benign |
Het |
| Dnah9 |
T |
C |
11: 65,732,159 (GRCm39) |
Y4249C |
probably damaging |
Het |
| Eif5b |
T |
A |
1: 38,087,974 (GRCm39) |
L990H |
probably damaging |
Het |
| Faap24 |
T |
C |
7: 35,094,388 (GRCm39) |
|
probably benign |
Het |
| Fryl |
T |
A |
5: 73,282,077 (GRCm39) |
H174L |
probably benign |
Het |
| Gabrr1 |
T |
C |
4: 33,132,696 (GRCm39) |
W15R |
probably benign |
Het |
| Gm15446 |
T |
C |
5: 110,091,347 (GRCm39) |
V533A |
probably benign |
Het |
| Gm6760 |
T |
A |
X: 63,195,259 (GRCm39) |
K63* |
probably null |
Het |
| Gne |
C |
T |
4: 44,042,244 (GRCm39) |
E444K |
possibly damaging |
Het |
| Gpr173 |
T |
A |
X: 151,130,036 (GRCm39) |
M146L |
possibly damaging |
Het |
| Hira |
C |
T |
16: 18,753,797 (GRCm39) |
S547L |
probably benign |
Het |
| Hnf1b |
A |
G |
11: 83,754,810 (GRCm39) |
H161R |
probably benign |
Het |
| Hnrnpm |
T |
A |
17: 33,877,364 (GRCm39) |
N53I |
probably damaging |
Het |
| Hs3st5 |
A |
T |
10: 36,708,584 (GRCm39) |
I40F |
probably benign |
Het |
| Hydin |
C |
T |
8: 111,276,430 (GRCm39) |
|
probably benign |
Het |
| Ift172 |
A |
G |
5: 31,411,657 (GRCm39) |
I1607T |
probably damaging |
Het |
| Igfn1 |
T |
C |
1: 135,887,639 (GRCm39) |
Q2475R |
probably damaging |
Het |
| Il6st |
T |
C |
13: 112,640,806 (GRCm39) |
S800P |
possibly damaging |
Het |
| Iqub |
G |
A |
6: 24,501,260 (GRCm39) |
|
probably benign |
Het |
| Itgb1 |
A |
T |
8: 129,448,853 (GRCm39) |
|
probably benign |
Het |
| Kctd21 |
G |
A |
7: 96,996,808 (GRCm39) |
E94K |
probably benign |
Het |
| Kir3dl2 |
A |
G |
X: 135,354,260 (GRCm39) |
V233A |
possibly damaging |
Het |
| Klra2 |
A |
T |
6: 131,197,187 (GRCm39) |
C271S |
probably damaging |
Het |
| Lacc1 |
A |
T |
14: 77,267,061 (GRCm39) |
C401S |
probably damaging |
Het |
| Lmna |
T |
C |
3: 88,389,885 (GRCm39) |
E580G |
probably damaging |
Het |
| Matn2 |
A |
G |
15: 34,345,296 (GRCm39) |
Y101C |
probably damaging |
Het |
| Mrps16 |
G |
A |
14: 20,441,457 (GRCm39) |
R116* |
probably null |
Het |
| Ndrg2 |
G |
T |
14: 52,143,674 (GRCm39) |
R333S |
probably damaging |
Het |
| Nf2 |
A |
G |
11: 4,732,194 (GRCm39) |
I507T |
possibly damaging |
Het |
| Nktr |
A |
G |
9: 121,578,356 (GRCm39) |
|
probably benign |
Het |
| Nkx3-1 |
G |
A |
14: 69,428,455 (GRCm39) |
|
probably benign |
Het |
| Npat |
T |
C |
9: 53,467,781 (GRCm39) |
|
probably null |
Het |
| Nrxn1 |
T |
C |
17: 90,872,801 (GRCm39) |
N1047S |
probably damaging |
Het |
| Nup210 |
A |
T |
6: 91,003,911 (GRCm39) |
I1402N |
possibly damaging |
Het |
| Or5d40 |
G |
T |
2: 88,015,624 (GRCm39) |
M134I |
possibly damaging |
Het |
| Parp14 |
G |
A |
16: 35,677,130 (GRCm39) |
A946V |
probably benign |
Het |
| Pdcl2 |
C |
T |
5: 76,460,328 (GRCm39) |
S182N |
probably benign |
Het |
| Pdia3 |
G |
A |
2: 121,262,858 (GRCm39) |
G275S |
probably damaging |
Het |
| Pla2g4a |
A |
G |
1: 149,716,455 (GRCm39) |
F669L |
probably benign |
Het |
| Plekha8 |
A |
G |
6: 54,606,805 (GRCm39) |
K367E |
probably damaging |
Het |
| Pola1 |
A |
G |
X: 92,531,693 (GRCm39) |
|
probably benign |
Het |
| Ppm1d |
C |
T |
11: 85,236,703 (GRCm39) |
T494I |
probably benign |
Het |
| Pramel16 |
T |
A |
4: 143,676,453 (GRCm39) |
Y217F |
probably benign |
Het |
| Prl6a1 |
A |
T |
13: 27,498,177 (GRCm39) |
|
probably benign |
Het |
| Ptprg |
T |
A |
14: 12,154,131 (GRCm38) |
S617R |
probably benign |
Het |
| R3hdm2 |
G |
A |
10: 127,280,313 (GRCm39) |
G45D |
probably damaging |
Het |
| Rev1 |
T |
A |
1: 38,098,204 (GRCm39) |
R780W |
probably null |
Het |
| Rnf139 |
T |
A |
15: 58,771,676 (GRCm39) |
F567Y |
probably damaging |
Het |
| Scarf1 |
T |
C |
11: 75,405,174 (GRCm39) |
V71A |
probably damaging |
Het |
| Shtn1 |
A |
G |
19: 58,988,372 (GRCm39) |
S438P |
probably damaging |
Het |
| Slc30a3 |
T |
A |
5: 31,246,067 (GRCm39) |
H221L |
probably benign |
Het |
| Smo |
A |
C |
6: 29,753,603 (GRCm39) |
I160L |
possibly damaging |
Het |
| Snapc5 |
A |
T |
9: 64,086,582 (GRCm39) |
|
probably benign |
Het |
| Snf8 |
G |
T |
11: 95,925,799 (GRCm39) |
|
probably benign |
Het |
| Spata31d1a |
T |
C |
13: 59,850,245 (GRCm39) |
S628G |
probably benign |
Het |
| Sphkap |
A |
T |
1: 83,258,145 (GRCm39) |
D199E |
probably damaging |
Het |
| Spring1 |
T |
C |
5: 118,397,154 (GRCm39) |
Y128H |
probably damaging |
Het |
| Stxbp5l |
T |
C |
16: 37,024,883 (GRCm39) |
T572A |
possibly damaging |
Het |
| Tln1 |
T |
C |
4: 43,547,756 (GRCm39) |
Q735R |
probably benign |
Het |
| Trim24 |
G |
A |
6: 37,848,169 (GRCm39) |
E42K |
probably benign |
Het |
| Trnt1 |
T |
A |
6: 106,754,869 (GRCm39) |
|
probably benign |
Het |
| Ttbk2 |
A |
T |
2: 120,604,353 (GRCm39) |
M215K |
probably damaging |
Het |
| Ttc8 |
C |
T |
12: 98,909,718 (GRCm39) |
|
probably benign |
Het |
| Ube3c |
A |
G |
5: 29,795,926 (GRCm39) |
Y105C |
probably damaging |
Het |
| Unc13c |
A |
G |
9: 73,438,265 (GRCm39) |
|
probably benign |
Het |
| Usp36 |
A |
G |
11: 118,153,854 (GRCm39) |
|
probably benign |
Het |
| Vcf2 |
C |
T |
X: 149,181,360 (GRCm39) |
A144T |
probably benign |
Het |
| Vmn2r102 |
T |
C |
17: 19,899,106 (GRCm39) |
S483P |
possibly damaging |
Het |
| Wdr95 |
A |
G |
5: 149,511,595 (GRCm39) |
T432A |
probably damaging |
Het |
| Wnk1 |
G |
T |
6: 119,903,644 (GRCm39) |
P2523H |
probably damaging |
Het |
| Xpo4 |
A |
G |
14: 57,875,665 (GRCm39) |
|
probably benign |
Het |
| Zar1 |
G |
T |
5: 72,737,886 (GRCm39) |
P71Q |
probably damaging |
Het |
| Zbtb41 |
T |
C |
1: 139,351,348 (GRCm39) |
Y154H |
probably benign |
Het |
| Zer1 |
G |
T |
2: 29,994,809 (GRCm39) |
|
probably benign |
Het |
| Zfp454 |
A |
G |
11: 50,765,012 (GRCm39) |
F140S |
probably benign |
Het |
|
| Other mutations in Thada |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00672:Thada
|
APN |
17 |
84,751,646 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL00902:Thada
|
APN |
17 |
84,755,404 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01634:Thada
|
APN |
17 |
84,700,786 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01689:Thada
|
APN |
17 |
84,754,116 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
IGL01693:Thada
|
APN |
17 |
84,754,072 (GRCm39) |
missense |
probably benign |
|
|
IGL01937:Thada
|
APN |
17 |
84,530,194 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01945:Thada
|
APN |
17 |
84,530,194 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02231:Thada
|
APN |
17 |
84,736,125 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02951:Thada
|
APN |
17 |
84,751,456 (GRCm39) |
missense |
probably benign |
0.16 |
|
IGL03167:Thada
|
APN |
17 |
84,766,277 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL03279:Thada
|
APN |
17 |
84,742,988 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03347:Thada
|
APN |
17 |
84,705,633 (GRCm39) |
missense |
probably damaging |
1.00 |
|
H8562:Thada
|
UTSW |
17 |
84,753,972 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03098:Thada
|
UTSW |
17 |
84,641,569 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0006:Thada
|
UTSW |
17 |
84,533,468 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0052:Thada
|
UTSW |
17 |
84,762,586 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0052:Thada
|
UTSW |
17 |
84,762,586 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0357:Thada
|
UTSW |
17 |
84,538,364 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0388:Thada
|
UTSW |
17 |
84,538,524 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0543:Thada
|
UTSW |
17 |
84,730,591 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0630:Thada
|
UTSW |
17 |
84,536,603 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0664:Thada
|
UTSW |
17 |
84,644,257 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0855:Thada
|
UTSW |
17 |
84,744,083 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0972:Thada
|
UTSW |
17 |
84,736,490 (GRCm39) |
splice site |
probably benign |
|
|
R1297:Thada
|
UTSW |
17 |
84,559,863 (GRCm39) |
splice site |
probably benign |
|
|
R1465:Thada
|
UTSW |
17 |
84,744,104 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1465:Thada
|
UTSW |
17 |
84,744,104 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1490:Thada
|
UTSW |
17 |
84,754,029 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R1789:Thada
|
UTSW |
17 |
84,755,462 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1789:Thada
|
UTSW |
17 |
84,755,461 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1802:Thada
|
UTSW |
17 |
84,771,835 (GRCm39) |
missense |
probably benign |
0.34 |
|
R1831:Thada
|
UTSW |
17 |
84,538,542 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1834:Thada
|
UTSW |
17 |
84,533,432 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R1881:Thada
|
UTSW |
17 |
84,744,130 (GRCm39) |
missense |
probably benign |
0.19 |
|
R1925:Thada
|
UTSW |
17 |
84,751,927 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1969:Thada
|
UTSW |
17 |
84,617,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1970:Thada
|
UTSW |
17 |
84,617,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1971:Thada
|
UTSW |
17 |
84,617,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2149:Thada
|
UTSW |
17 |
84,749,192 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2191:Thada
|
UTSW |
17 |
84,753,949 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2571:Thada
|
UTSW |
17 |
84,762,068 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3405:Thada
|
UTSW |
17 |
84,538,213 (GRCm39) |
splice site |
probably benign |
|
|
R3406:Thada
|
UTSW |
17 |
84,538,213 (GRCm39) |
splice site |
probably benign |
|
|
R3916:Thada
|
UTSW |
17 |
84,749,210 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4044:Thada
|
UTSW |
17 |
84,749,135 (GRCm39) |
missense |
probably benign |
0.41 |
|
R4461:Thada
|
UTSW |
17 |
84,733,665 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4662:Thada
|
UTSW |
17 |
84,743,078 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4696:Thada
|
UTSW |
17 |
84,733,614 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R4786:Thada
|
UTSW |
17 |
84,766,283 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R4803:Thada
|
UTSW |
17 |
84,580,245 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4835:Thada
|
UTSW |
17 |
84,748,532 (GRCm39) |
splice site |
probably null |
|
|
R4872:Thada
|
UTSW |
17 |
84,754,027 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4898:Thada
|
UTSW |
17 |
84,755,470 (GRCm39) |
splice site |
probably null |
|
|
R4903:Thada
|
UTSW |
17 |
84,559,828 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R4929:Thada
|
UTSW |
17 |
84,751,654 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4959:Thada
|
UTSW |
17 |
84,751,611 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5071:Thada
|
UTSW |
17 |
84,693,960 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5092:Thada
|
UTSW |
17 |
84,751,896 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5398:Thada
|
UTSW |
17 |
84,733,614 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5480:Thada
|
UTSW |
17 |
84,739,682 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5552:Thada
|
UTSW |
17 |
84,736,558 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5575:Thada
|
UTSW |
17 |
84,723,827 (GRCm39) |
splice site |
probably null |
|
|
R5623:Thada
|
UTSW |
17 |
84,499,411 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5688:Thada
|
UTSW |
17 |
84,759,155 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5704:Thada
|
UTSW |
17 |
84,538,329 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6008:Thada
|
UTSW |
17 |
84,744,062 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6013:Thada
|
UTSW |
17 |
84,580,228 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6072:Thada
|
UTSW |
17 |
84,499,434 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R6156:Thada
|
UTSW |
17 |
84,700,795 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6243:Thada
|
UTSW |
17 |
84,744,030 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6449:Thada
|
UTSW |
17 |
84,736,601 (GRCm39) |
missense |
probably benign |
|
|
R6453:Thada
|
UTSW |
17 |
84,723,751 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6474:Thada
|
UTSW |
17 |
84,751,339 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R6732:Thada
|
UTSW |
17 |
84,761,842 (GRCm39) |
splice site |
probably null |
|
|
R6907:Thada
|
UTSW |
17 |
84,700,897 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7117:Thada
|
UTSW |
17 |
84,538,214 (GRCm39) |
splice site |
probably null |
|
|
R7167:Thada
|
UTSW |
17 |
84,538,391 (GRCm39) |
missense |
probably benign |
|
|
R7221:Thada
|
UTSW |
17 |
84,771,794 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7470:Thada
|
UTSW |
17 |
84,533,469 (GRCm39) |
missense |
probably benign |
|
|
R7753:Thada
|
UTSW |
17 |
84,559,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7809:Thada
|
UTSW |
17 |
84,759,265 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R7882:Thada
|
UTSW |
17 |
84,736,624 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R7971:Thada
|
UTSW |
17 |
84,580,197 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R8004:Thada
|
UTSW |
17 |
84,499,633 (GRCm39) |
missense |
probably benign |
|
|
R8153:Thada
|
UTSW |
17 |
84,700,855 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8254:Thada
|
UTSW |
17 |
84,533,468 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8426:Thada
|
UTSW |
17 |
84,530,131 (GRCm39) |
missense |
probably benign |
0.17 |
|
R8438:Thada
|
UTSW |
17 |
84,743,057 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8670:Thada
|
UTSW |
17 |
84,739,774 (GRCm39) |
missense |
probably benign |
0.16 |
|
R8679:Thada
|
UTSW |
17 |
84,536,637 (GRCm39) |
missense |
probably benign |
0.28 |
|
R8952:Thada
|
UTSW |
17 |
84,736,524 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8983:Thada
|
UTSW |
17 |
84,538,515 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9009:Thada
|
UTSW |
17 |
84,759,203 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R9050:Thada
|
UTSW |
17 |
84,736,629 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9091:Thada
|
UTSW |
17 |
84,538,589 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9225:Thada
|
UTSW |
17 |
84,749,172 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9251:Thada
|
UTSW |
17 |
84,538,564 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9270:Thada
|
UTSW |
17 |
84,538,589 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9299:Thada
|
UTSW |
17 |
84,749,205 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9337:Thada
|
UTSW |
17 |
84,749,205 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9360:Thada
|
UTSW |
17 |
84,499,410 (GRCm39) |
missense |
probably benign |
|
|
R9416:Thada
|
UTSW |
17 |
84,766,292 (GRCm39) |
nonsense |
probably null |
|
|
R9484:Thada
|
UTSW |
17 |
84,736,619 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9584:Thada
|
UTSW |
17 |
84,733,605 (GRCm39) |
missense |
probably benign |
|
|
R9631:Thada
|
UTSW |
17 |
84,538,584 (GRCm39) |
missense |
probably benign |
0.17 |
|
Z1176:Thada
|
UTSW |
17 |
84,751,858 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
| Predicted Primers |
PCR Primer
(F):5'- CAAATCAGCCTTGAGTGTGAGAGCA -3'
(R):5'- ATGGAGACCAAAGCATTGGTTCTGAA -3'
Sequencing Primer
(F):5'- AGACTGGAGTCAGCCATCTG -3'
(R):5'- TGTGCACAAATTGAATG -3'
|
| Posted On |
2013-07-11 |
Incidental Mutation