Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL03062:Vmn2r13'

409479

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn2r13

Ensembl Gene

ENSMUSG00000091635

Gene Name

vomeronasal 2, receptor 13

Synonyms

Gm4867

Accession Numbers

Is this an essential gene?

Probably non essential (E-score: 0.078) question?

Stock #

IGL03062

Quality Score

Status

Chromosome

Chromosomal Location

109156068-109192107 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 109156282 bp

Zygosity

Heterozygous

Amino Acid Change

Phenylalanine to Serine at position 761 (F761S)

Ref Sequence

ENSEMBL: ENSMUSP00000052977 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000053253]

Predicted Effect

probably damaging
Transcript: ENSMUST00000053253
AA Change: F761S

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000052977
Gene: ENSMUSG00000091635
AA Change: F761S

Domain	Start	End	E-Value	Type
signal peptide	1	21	N/A	INTRINSIC
Pfam:ANF_receptor	76	463	2.8e-29	PFAM
Pfam:NCD3G	506	560	1.3e-18	PFAM
Pfam:7tm_3	593	828	1.8e-54	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 52 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4932438A13Rik	T	C	3: 37,038,517		probably benign	Het
Abcb10	C	T	8: 123,954,315	R714Q	possibly damaging	Het
Abcb5	T	A	12: 118,936,087	I282L	probably benign	Het
Aox1	A	T	1: 58,078,465	E835D	probably benign	Het
Arhgap17	C	T	7: 123,321,874		probably null	Het
Calcr	C	T	6: 3,693,718	V359I	probably benign	Het
Chd9	T	A	8: 91,015,267		probably benign	Het
Col28a1	T	C	6: 8,017,029		probably benign	Het
Dnajc11	A	G	4: 151,970,861	E171G	possibly damaging	Het
Efhd1	T	C	1: 87,264,684	F79L	possibly damaging	Het
Fam83a	A	T	15: 57,993,077		probably null	Het
Fam98a	A	G	17: 75,540,105		probably benign	Het
Ficd	A	G	5: 113,738,253	Y163C	probably damaging	Het
Filip1l	T	C	16: 57,506,804	S66P	probably damaging	Het
Fmo5	A	G	3: 97,635,593	Y73C	probably damaging	Het
Galnt12	C	A	4: 47,122,566	R574S	possibly damaging	Het
Klc3	C	A	7: 19,395,062	G461W	probably damaging	Het
Lmo7	A	T	14: 101,912,079	T973S	possibly damaging	Het
Loxl1	C	A	9: 58,311,910	G326V	possibly damaging	Het
Lrrc24	A	G	15: 76,718,304	V127A	probably benign	Het
Lyrm1	T	C	7: 119,916,131		probably benign	Het
Med28	G	A	5: 45,522,469	V65I	probably damaging	Het
Mgat4c	T	C	10: 102,388,461	Y179H	probably damaging	Het
Micall1	A	C	15: 79,114,681	N58T	probably damaging	Het
Ncoa4	T	A	14: 32,173,420	M72K	possibly damaging	Het
Nutm1	T	C	2: 112,248,933	Q879R	probably benign	Het
Olfr1428	C	T	19: 12,109,148	V133I	probably benign	Het
Olfr870	T	A	9: 20,171,167	I135F	probably damaging	Het
Olfr965	T	A	9: 39,720,035	D269E	probably benign	Het
Phf11b	T	C	14: 59,324,924	I177M	probably damaging	Het
Pin1rt1	T	G	2: 104,714,707	I27L	probably benign	Het
Plxna2	T	C	1: 194,762,550	V750A	possibly damaging	Het
Pou5f1	A	T	17: 35,510,039	N126I	possibly damaging	Het
Ptprn	A	T	1: 75,247,873	H946Q	possibly damaging	Het
Rnf43	G	T	11: 87,732,304	G744*	probably null	Het
Rsbn1	C	A	3: 103,953,629		probably benign	Het
Sars2	T	A	7: 28,746,781	I145N	possibly damaging	Het
Sh3tc2	A	T	18: 62,011,880	E1135V	probably damaging	Het
Shroom1	A	G	11: 53,463,379	D42G	probably benign	Het
Sidt2	A	G	9: 45,942,683		probably null	Het
Slc39a8	T	C	3: 135,886,797		probably benign	Het
Slc9c1	T	C	16: 45,599,758	S1059P	probably benign	Het
Socs6	A	T	18: 88,869,846	M315K	probably benign	Het
Soga3	T	A	10: 29,198,949	F911Y	probably damaging	Het
Speer2	T	C	16: 69,857,977	E200G	probably damaging	Het
Sult2a5	T	A	7: 13,624,182		probably null	Het
Tmbim1	A	T	1: 74,291,699	I168N	possibly damaging	Het
Trim38	T	C	13: 23,782,963	V131A	probably damaging	Het
Ube2o	A	G	11: 116,541,642	S833P	probably damaging	Het
Uggt2	T	C	14: 119,075,346	I350M	probably damaging	Het
Unc80	A	G	1: 66,509,489	D640G	probably damaging	Het
Vmn2r54	C	T	7: 12,632,428	C193Y	probably damaging	Het

Other mutations in Vmn2r13

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00965:Vmn2r13	APN	5	109156098	missense	probably damaging	1.00
IGL01373:Vmn2r13	APN	5	109156702	missense	probably damaging	1.00
IGL01946:Vmn2r13	APN	5	109174219	missense	probably benign	0.01
IGL01971:Vmn2r13	APN	5	109174115	missense	probably benign	0.01
IGL02636:Vmn2r13	APN	5	109192017	missense	probably damaging	0.98
IGL03173:Vmn2r13	APN	5	109171779	missense	possibly damaging	0.95
IGL03301:Vmn2r13	APN	5	109158089	missense	probably damaging	0.99
IGL03383:Vmn2r13	APN	5	109156532	missense	probably damaging	0.98
IGL03048:Vmn2r13	UTSW	5	109156285	missense	probably damaging	1.00
R0123:Vmn2r13	UTSW	5	109175049	missense	probably benign	0.00
R0134:Vmn2r13	UTSW	5	109175049	missense	probably benign	0.00
R0220:Vmn2r13	UTSW	5	109156466	missense	probably damaging	1.00
R0225:Vmn2r13	UTSW	5	109175049	missense	probably benign	0.00
R0393:Vmn2r13	UTSW	5	109156529	missense	probably benign	0.01
R0410:Vmn2r13	UTSW	5	109173813	missense	probably benign	0.35
R0787:Vmn2r13	UTSW	5	109156847	missense	probably damaging	0.99
R1200:Vmn2r13	UTSW	5	109174202	missense	probably damaging	1.00
R1448:Vmn2r13	UTSW	5	109174135	missense	probably damaging	1.00
R1782:Vmn2r13	UTSW	5	109158174	missense	probably benign	0.08
R1939:Vmn2r13	UTSW	5	109191986	missense	possibly damaging	0.88
R2029:Vmn2r13	UTSW	5	109192077	missense	probably benign	0.13
R2125:Vmn2r13	UTSW	5	109158192	missense	probably benign	0.00
R2126:Vmn2r13	UTSW	5	109158192	missense	probably benign	0.00
R2379:Vmn2r13	UTSW	5	109171778	missense	probably benign	0.05
R2680:Vmn2r13	UTSW	5	109174312	missense	possibly damaging	0.66
R2888:Vmn2r13	UTSW	5	109191974	missense	possibly damaging	0.88
R2889:Vmn2r13	UTSW	5	109191974	missense	possibly damaging	0.88
R2890:Vmn2r13	UTSW	5	109191974	missense	possibly damaging	0.88
R3014:Vmn2r13	UTSW	5	109171761	missense	possibly damaging	0.81
R3683:Vmn2r13	UTSW	5	109156855	missense	probably damaging	1.00
R4074:Vmn2r13	UTSW	5	109156700	missense	probably damaging	1.00
R4599:Vmn2r13	UTSW	5	109156456	missense	probably damaging	1.00
R4614:Vmn2r13	UTSW	5	109175199	missense	probably benign	0.01
R4805:Vmn2r13	UTSW	5	109156465	missense	probably damaging	1.00
R4822:Vmn2r13	UTSW	5	109174072	missense	probably damaging	0.99
R4943:Vmn2r13	UTSW	5	109175049	missense	probably benign	0.00
R5263:Vmn2r13	UTSW	5	109173975	missense	probably benign	0.00
R5297:Vmn2r13	UTSW	5	109191939	missense	probably benign	0.00
R5502:Vmn2r13	UTSW	5	109173714	missense	probably damaging	1.00
R5554:Vmn2r13	UTSW	5	109191994	missense	possibly damaging	0.49
R5563:Vmn2r13	UTSW	5	109173980	missense	probably benign	0.00
R5819:Vmn2r13	UTSW	5	109174100	missense	possibly damaging	0.79
R6074:Vmn2r13	UTSW	5	109174301	missense	probably benign	0.04
R6416:Vmn2r13	UTSW	5	109174116	missense	probably damaging	0.99
R6419:Vmn2r13	UTSW	5	109175219	missense	possibly damaging	0.87
R6484:Vmn2r13	UTSW	5	109156674	nonsense	probably null
R6486:Vmn2r13	UTSW	5	109156559	missense	probably benign	0.05
R6545:Vmn2r13	UTSW	5	109156940	splice site	probably null
R6700:Vmn2r13	UTSW	5	109175072	missense	probably benign	0.00
R6897:Vmn2r13	UTSW	5	109158149	missense	possibly damaging	0.90
R6957:Vmn2r13	UTSW	5	109156887	nonsense	probably null
R7276:Vmn2r13	UTSW	5	109173779	missense	probably damaging	1.00
R7363:Vmn2r13	UTSW	5	109192043	missense	probably benign	0.03
R7443:Vmn2r13	UTSW	5	109192043	missense	probably benign	0.03
R7555:Vmn2r13	UTSW	5	109171691	splice site	probably null
R7607:Vmn2r13	UTSW	5	109173640	missense	probably damaging	0.98
R7719:Vmn2r13	UTSW	5	109171752	missense	probably benign	0.00
R8116:Vmn2r13	UTSW	5	109175060	missense	probably benign	0.12
R8242:Vmn2r13	UTSW	5	109175006	missense	possibly damaging	0.65
R8294:Vmn2r13	UTSW	5	109175112	missense	probably benign	0.02
R8340:Vmn2r13	UTSW	5	109174140	missense	probably benign	0.00
X0066:Vmn2r13	UTSW	5	109156219	missense	probably benign	0.44

Posted On

2016-08-02